Genome editing platform

Based on the CRISPR/Cas9 bases genome editing technology different applications can be used. Service is provided during project planning, strategy design, genotyping/ colony maintenance and injection. The service is available by scientific cooperation. For details feel free to contact:

Prof. Dr. Boris Fehse

Department of Stem Cell Transplantation

+49 (0) 40 7410 - 55518

fehse@uke.de

Isotope lab & irradiation core facility

For researchers an isotope lab and an irradiation facility are available on UKE campus. Both are run by the Vice Deanery for Research. For further details and guidelines please follow the links.

Isotope lab facility

Irradiation facility

Radiobiology platform

In vitro X-irradiations and assays for clonogenic cell survival, chromosomal aberrations as well as DNA damage & repair, signalling and cell cycle/replication dynamics are available through scientific collaboration at the Laboratory of Radiobiology & Experimental Radiation Oncology .

Contact:

Strahlenbiologie@uke.de

Small animal x-irradiation platform

The recently established Precision X-Ray “SmART+” facility enables the precise locally ablative irradiation of tumors in small animal models. Cross sectional imaging with two different µCT imaging modalities (50µm and 20µm spatial resolution), several collimators for beam shaping, Monte-Carlo-based treatment planning and a high precision treatment table allow us to mimic the clinical image-guided radiotherapy setting. Furthermore, bioluminescence imaging in therapy position is possible, which allows functional tumor imaging.

Contact:

PD Dr. Dr. Thorsten Frenzel

Department of Radiotherapy

+49 (0) 40 7410 - 54031

frenzel@uke.de

Transgenic core facility

This core facility is located at the Center for Molecular Neurobiology Hamburg (ZMNH).

For further details please contact:

ZMNH Core facility for transgenic mice

+49 (0) 40 7410 - 56663

Webiste of this core unit