- Fachärztin für Innere Medizin
Fachgebiete
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Infektiologie
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Tropenmedizin
Tätigkeitsschwerpunkte
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Infektiologie
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Emerging Infections
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Impfstoffentwicklung
Lebenslauf
Auszeichnungen
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2022: Ehren-Alster-Schleusenwärterin
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2022: Heinz-Ansmann-Preis für AIDS-Forschung
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2021: Hammonia des Landesfrauenrats Hamburg
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2021: Bürgerpreis der Hamburgischen Bürgervereine
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2020: German Medical Award - Medizinerin des Jahres 2020
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2019: Pettenkofer-Preis 2019 (Pettenkofer-Stiftung, München)
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2018: DZIF Prize for Translational Infection Research (www.dzif.de)
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2013: Honorary Professor, University of KwaZulu-Natal, Durban, South Africa
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2008: Edward H. Kass Award for Clinical Excellency, Massachussets ID Society
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1999: Ralph A. Neal Memorial Prize, London School of Hygiene and Tropical Medicine
Mitgliedschaften
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Deutsche Gesellschaft für Infektiologie (DGI)
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Deutsche Gesellschaft für Immunologie (DGfI)
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Deutsche AIDS-Gesellschaft (DAIG)
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Deutsche Gesellschaft für Tropenmedizin und internationale Gesundheit (DTG)
Publikationen
S2k-Leitlinie Gastrointestinale Infektionen der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
Z GASTROENTEROL. 2024;62(7):1090-1149.
Invasive Pilzinfektionen: Herausforderungen und aktuelle Entwicklungen
Addo M
DEUT MED WOCHENSCHR. 2024;149(10):541.
RSV vaccination strategies for high-risk patients 2023: a collaborative position paper by leading German medical societies and organizations
Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M
INFECTION. 2024;52(1):285-288.
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON)
Appel K, Nürnberger C, Bahmer T, Förster C, Polidori M, Kohls M, Kraus T, Hettich-Damm N, Petersen J, Blaschke S, Bröhl I, Butzmann J, Dashti H, Deckert J, Dreher M, Fiedler K, Finke C, Geisler R, Hanses F, Hopff S, Jensen B, Konik M, Lehnert K, de Miranda S, Mitrov L, Miljukov O, Reese J, Rohde G, Scherer M, Tausche K, Tebbe J, Vehreschild J, Voit F, Wagner P, Weigl M, Lemhöfer C
INFECTION. 2024 [Epub ahead of print].
Prevalence of infectious diseases, immunity to vaccine-preventable diseases and chronic medical conditions among Ukrainian refugees in Germany - A cross sectional study from the German Network University Medicine (NUM)
Brinkmann F, Friedrichs A, Behrens G, Behrens P, Berner R, Caliebe A, Denkinger C, Giesbrecht K, Gussew A, Hoffmann A, Hojenski L, Hovardovska O, Dopfer-Jablonka A, Kaasch A, Kobbe R, Kraus M, Lindner A, Maier C, Mitrov L, Nauck M, de Miranda S, Scherer M, Schmiedel Y, Stahl D, Timmesfeld N, Toepfner N, Vehreschild J, Wohlgemuth W, Petersmann A, Vehreschild M
J INFECT PUBLIC HEAL. 2024;17(4):642-649.
SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition
Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, Bosurgi L, Dutzmann J, Sedding D, Frese T, Girndt M, Hoell J, Gekle M, Addo M, Schulze Zur Wiesch J, Mikolajczyk R, Binder M, Schultheiß C
NPJ VACCINES. 2024;9(1):23.
Identification of a spike-specific CD8+ T cell epitope following vaccination against the Middle East respiratory syndrome coronavirus in humans
Harrer C, Mayer L, Fathi A, Lassen S, Ly M, Zinser M, Wolf T, Becker S, Sutter G, Dahlke C, Addo M
J INFECT DIS. 2024;230(2):e327-e332.
Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV-2 variants delta and omicron-results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP)
Hopff S, Appel K, Miljukov O, Schneider J, Addo M, Bals R, Bercker S, Blaschke S, Bröhl I, Büchner N, Dashti H, Erber J, Friedrichs A, Geisler R, Göpel S, Hagen M, Hanses F, Jensen B, Keul M, Krawczyk A, Lorenz-Depiereux B, Meybohm P, Milovanovic M, Mitrov L, Nürnberger C, Obst W, Römmele C, Schäfer C, Scheer C, Scherer M, Schmidt J, Seibel K, Sikdar S, Tebbe J, Tepasse P, Thelen P, Vehreschild M, Weismantel C, Vehreschild J
INFECTION. 2024 [Epub ahead of print].
Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies Detected 1 Year After BNT162b2 Vaccination in Children
Kobbe R, Rau C, Schulze-Sturm U, Stahl F, Fonseca-Brito L, Diemert A, Lütgehetmann M, Addo M, Arck P, Weskamm L
PEDIATR INFECT DIS J. 2024 [Epub ahead of print].
Challenges in Diagnosing and Treating Acutely Febrile Children with Suspected Malaria at Health Care Facilities in the Lake Mwanza Region of Tanzania
Koliopoulos P, Kayange N, Jensen C, Gröndahl B, Eichmann J, Daniel T, Huth F, Eckert T, Klamm N, Follmann M, Medina-Montaño G, Hokororo A, Pretsch L, Klüber J, Schmidt C, Züchner A, Addo M, Okamo B, Mshana S, Gehring S
AM J TROP MED HYG. 2024;110(2):202-208.
Editorial zur Aktualisierung der S2k-Leitlinie Gastrointestinale Infektionen v2.0
Manthey C, Addo M, Stallmach A, Lohse A
Z GASTROENTEROL. 2024;62(7):1088-1089.
MVA-based vaccine candidates encoding the native or prefusion-stabilized SARS-CoV-2 spike reveal differential immunogenicity in humans
Mayer L, Weskamm L, Fathi A, Kono M, Heidepriem J, Krähling V, Mellinghoff S, Ly M, Friedrich M, Hardtke S, Borregaard S, Hesterkamp T, Loeffler F, Volz A, Sutter G, Becker S, Dahlke C, Addo M
NPJ VACCINES. 2024;9(1):20.
Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia
Mellinghoff S, Robrecht S, Sprute R, Mayer L, Weskamm L, Dahlke C, Gruell H, Teipel F, Schlößer H, Siepmann K, Thelen M, Fink A, Fischer K, Klein F, Addo M, Kolovou A, Cornely O, Eichhorst B, Hallek M, Langerbeins P
EUR J HAEMATOL. 2024;112(5):788-793.
Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccine
Odak I, Riemann L, Sandrock I, Cossmann A, Ramos G, Hammerschmidt S, Ritter C, Friedrichsen M, Hassan A, Dopfer-Jablonka A, Stankov M, Weskamm L, Addo M, Ravens I, Willenzon S, Schimrock A, Ristenpart J, Janssen A, Barros-Martins J, Hansen G, Falk C, Behrens G, Förster R
EBIOMEDICINE. 2024;99:.
Lack of evidence of acute HEV infections as a sexually transmitted disease: Data from a German cohort of PrEP users
Schäfer G, Lübke R, Degen O, Mader M, Scheiter R, Wolski A, Addo M, Schulze Zur Wiesch J, Pischke S
BRAZ J INFECT DIS. 2024;28(1):103720.
High vaccination coverage and infection rate result in a robust SARS-CoV-2-specific immunity in the majority of liver cirrhosis and transplant patients: A single-center cross-sectional study
von der Schulenburg P, Herting A, Harberts A, Lütgehetmann M, Jahnke-Triankowski J, Pischke S, Piecha F, Drolz A, Jörg V, Hübener P, Wehmeyer M, Addo M, Fischer L, Lohse A, Schulze Zur Wiesch J, Sterneck M
UNITED EUR GASTROENT. 2024;12(3):339-351.
Dissecting humoral immune responses to an MVA-vectored MERS-CoV vaccine in humans using a systems serology approach
Weskamm L, Tarnow P, Harms C, Huchon M, Raadsen M, Friedrich M, Rübenacker L, Grüttner C, Garcia M, Koch T, Becker S, Sutter G, Lhomme E, Haagmans B, Fathi A, Blois S, Dahlke C, Richert L, Addo M
ISCIENCE. 2024;27(8):110470.
Think Tbc!: An Tuberkulose denken, rechtzeitig diagnostizieren und sachgerecht behandeln
Addo M
DEUT MED WOCHENSCHR. 2023;148(19):1213-1214.
Positionspapier zur RSV-Schutzimpfung bei besonders gefährdeten Patientinnen und Patienten der Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V.
Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M
2023.
Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans
Beisel C, Jordan-Paiz A, Köllmann S, Ahrenstorf A, Padoan B, Barkhausen T, Addo M, Altfeld M
BIOL SEX DIFFER. 2023;14(1):11.
Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.
Mini-laparoscopy as a diagnostic tool for abdominal tuberculosis: a retrospective series of 29 cases
Brehm T, Ndzedzeka-Völz N, Wehmeyer M, Christner M, Clauditz T, Hübener P, Addo M, Lohse A, Schmiedel S
SURG ENDOSC. 2023;37(3):1830-1837.
Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
Cords L, Woost R, Kummer S, Brehm T, Kluge S, Schmiedel S, Jordan S, Lohse A, Altfeld M, Addo M, Schulze Zur Wiesch J, Beisel C
CYTOKINE. 2023;162:.
Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
Davi S, Okwu D, Luetgehetmann M, Abba F, Aepfelbacher M, Endamne L, Alabi A, Zoleko-Manego R, Mombo-Ngoma G, Mahmoudou S, Addo M, Ramharter M, Mischlinger J
INFECT DIS POVERTY. 2023;12(1):.
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial
Denkinger C, Janssen M, Schäkel U, Gall J, Leo A, Stelmach P, Weber S, Krisam J, Baumann L, Stermann J, Merle U, Weigand M, Nusshag C, Bullinger L, Schrezenmeier J, Bornhäuser M, Alakel N, Witzke O, Wolf T, Vehreschild M, Schmiedel S, Addo M, Herth F, Kreuter M, Tepasse P, Hertenstein B, Hänel M, Morgner A, Kiehl M, Hopfer O, Wattad M, Schimanski C, Celik C, Pohle T, Ruhe M, Kern W, Schmitt A, Lorenz H, Souto-Carneiro M, Gaeddert M, Halama N, Meuer S, Kräusslich H, Müller B, Schnitzler P, Parthé S, Bartenschlager R, Gronkowski M, Klemmer J, Schmitt M, Dreger P, Kriegsmann K, Schlenk R, Müller-Tidow C
NAT CANCER. 2023;4(1):96-107.
Predictors of somatic symptom burden in healthcare professionals during the COVID-19 pandemic: an 8-week follow-up study
Engelmann P, Toussaint A, Addo M, Brehm T, Lohse A, Weigel A, Thompson M, Löwe B
J MENT HEALTH. 2023;32(6):1111-1121.
High burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022
Ettemeyer M, Florey M, Tanida K, Jochum J, Schulze-Sturm U, Lütgehetmann M, Baehr M, Addo M, Schmiedel S, Rohde H, Koch T
INFECTION. 2023;51(5):1569-1575.
Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase-producing Enterobacterales in sub-Saharan Africa
Heinemann M, Kleinjohann L, Rolling T, Winter D, Hackbarth N, Ramharter M, Addo M, Eibach D, Phillips R, Owusu-Ofori A, Vinnemeier C
CLIN MICROBIOL INFEC. 2023;29(3):340-345.
Tecovirimat for the treatment of severe Mpox in Germany
Hermanussen L, Brehm T, Wolf T, Boesecke C, Schlabe S, Borgans F, Monin M, Jensen B, Windhaber S, Scholten S, Jordan S, Lütgehetmann M, Wiesch J, Addo M, Mikolajewska A, Niebank M, Schmiedel S
INFECTION. 2023;51(5):1563-1568.
Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern-A first case-series experience
Hermanussen L, Grewe I, Tang H, Nörz D, Bal L, Pfefferle S, Unger S, Hoffmann C, Berzow D, Kohsar M, Aepfelbacher M, Lohse A, Addo M, Lütgehetmann M, Schulze zur Wiesch J, Schmiedel S
J MED VIROL. 2023;95(1):e28181.
Clinical Outcomes of SARS-CoV-2 Breakthrough Infections in Liver Transplant Recipients during the Omicron Wave
Herting A, Jahnke-Triankowski J, Harberts A, Schaub G, Lütgehetmann M, Ruether D, Fischer L, Addo M, Lohse A, Schulze Zur Wiesch J, Sterneck M
VIRUSES-BASEL. 2023;15(2):.
Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease
Hufnagel K, Fathi A, Stroh N, Klein M, Skwirblies F, Girgis R, Dahlke C, Hoheisel J, Lowy C, Schmidt R, Griesbeck A, Merle U, Addo M, Schröder C
COMMUN MED-LONDON. 2023;3(1):51.
Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability
Huttner A, Agnandji S, Engler O, Hooper J, Kwilas S, Ricks K, Clements T, Jonsdottir H, Nakka S, Rothenberger S, Kremsner P, Züst R, Medaglini D, Ottenhoff T, Harandi A, Siegrist C
CLIN MICROBIOL INFEC. 2023;29(12):1587-1594.
History of cerebrovascular disease but not dementia increases the risk for secondary vascular events during SARS-CoV-2 infection with presumed Omicron variant: a retrospective observational study
Mayer C, Woo M, Brehm T, Heyer A, Fischer M, Fischbach F, Bal L, Addo M, Kluge S, Thomalla G, Schweingruber N, Wiesch J
EUR J NEUROL. 2023;30(8):2297-2304.
β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: In vitro validation with focus on saliva from COVID-19 patients for scent dog training
Pilchová V, Prajeeth C, Jendrny P, Twele F, Meller S, Pink I, Fathi A, Addo M, Volk H, Osterhaus A, von Köckritz-Blickwede M, Schulz C
J VIROL METHODS. 2023;317:.
Monkeypox Virus Cross-Neutralizing Antibodies in Clinical Trial Participants Vaccinated With Modified Vaccinia Virus Ankara Encoding Middle East Respiratory Syndrome–Coronavirus Spike Protein
Raadsen M, Dahlke C, Fathi A, Lamers M, van den Doel P, Zaeck L, van Royen M, de Bruin E, Sikkema R, Koopmans M, van Gorp E, Sutter G, de Vries R, Addo M, Haagmans B
J INFECT DIS. 2023;228(5):586-590.
Symptoms of illness during travel and risk factors for non-adherence to malaria prophylaxis-a cross-sectional study in travellers from Germany
Reinsberg F, Moehlmann M, Krumkamp R, Landsmann L, Heitkamp C, Jochum J, Addo M, Ramharter M, Radt C, Rothe C, Vinnemeier C, Kreuels B
J TRAVEL MED. 2023;30(3):taad055.
Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort
Shi Y, Strobl R, Apfelbacher C, Bahmer T, Geisler R, Heuschmann P, Horn A, Hoven H, Keil T, Krawczak M, Krist L, Lemhöfer C, Lieb W, Lorenz-Depiereux B, Mikolajczyk R, Montellano F, Reese J, Schreiber S, Skoetz N, Störk S, Vehreschild J, Witzenrath M, Grill E
INFECTION. 2023;51(6):1679-1694.
Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses
Westphal T, Mader M, Karsten H, Cords L, Knapp M, Schulte S, Hermanussen L, Peine S, Ditt V, Grifoni A, Addo M, Huber S, Sette A, Lütgehetmann M, Pischke S, Kwok W, Sidney J, Schulze Zur Wiesch J
FRONT IMMUNOL. 2023;14:.
Higher Risk of HEV Transmission and Exposure among Blood Donors in Europe and Asia in Comparison to North America: A Meta-Analysis
Wolski A, Pischke S, Ozga A, Addo M, Horvatits T
PATHOGENS. 2023;12(3):425.
Sotrovimab in Hospitalized Patients with SARS-CoV-2 Omicron Variant Infection: a Propensity Score-Matched Retrospective Cohort Study
Woo M, Brehm T, Fischer M, Heyer A, Wichmann D, Jordan S, Nörz D, Lütgehetmann M, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
MICROBIOL SPECTR. 2023;11(1):.
Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.
Vagus nerve inflammation contributes to dysautonomia in COVID-19
Woo M, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, Mayer C, Bal L, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm T, Lütgehetmann M, Schädler J, Addo M, Schulze Zur Wiesch J, Ondruschka B, Friese M, Glatzel M
ACTA NEUROPATHOL. 2023;146(3):387-394.
Notfallimpfstoffe: Wie sieht die Zukunft aus?
Addo M
2022. Infektionen und Gesellschaft. Lohse A, Mettenleiter T (Hrsg.). 1. Aufl. Berlin, Heidelberg: Springer Spektrum, Berlin, Heidelberg, 68-71.
Reisemedizin nimmt wieder an Fahrt auf!
Addo M
DEUT MED WOCHENSCHR. 2022;147(12):729-730.
T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function in mice
Brandi J, Lehmann C, Kaminski L, Schulze Zur Wiesch J, Addo M, Ramharter M, Mackroth M, Jacobs T, Riehn M
EUR J IMMUNOL. 2022;52(2):312-327.
Attitudes, practices, and obstacles towards influenza vaccination for international travelers among travel health advisors in Germany: A questionnaire-based survey
Brehm T, Jordan S, Addo M, Ramharter M, Kreuels B
TRAVEL MED INFECT DI. 2022;45:.
Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants
Brehm T, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, Nörz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo M, Schmiedel S, Lütgehetmann M
J MED VIROL. 2022;94(10):5038-5043.
Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.
High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19
Cords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson A, Kwok W, Günther T, Fischer N, Wittner M, Addo M, Huber S, Schulze Zur Wiesch J
VIRUSES-BASEL. 2022;14(6):.
SARS-CoV-2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
Duengelhoef P, Hartl J, Rüther D, Steinmann S, Brehm T, Weltzsch J, Glaser F, Schaub G, Sterneck M, Sebode M, Weiler-Normann C, Addo M, Lütgehetmann M, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
UNITED EUR GASTROENT. 2022;10(3):319-329.
Risk factors for worsening of somatic symptom burden in a prospective cohort during the COVID-19 pandemic
Engelmann P, Löwe B, Brehm T, Weigel A, Ullrich F, Addo M, Schulze zur Wiesch J, Lohse A, Toussaint A
FRONT PSYCHOL. 2022;13:1022203.
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
Fathi A, Dahlke C, Krähling V, Kupke A, Okba N, Raadsen M, Heidepriem J, Müller M, Paris G, Lassen-Haartje S, Klüver M, Volz A, Koch T, Ly M, Friedrich M, Fux R, Tscherne A, Kalodimou G, Schmiedel S, Corman V, Hesterkamp T, Drosten C, Loeffler F, Haagmans B, Sutter G, Becker S, Addo M
NAT COMMUN. 2022;13(1):4182.
Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients
Hagemann K, Riecken K, Jung J, Hildebrandt H, Menzel S, Bunders M, Fehse B, Koch-Nolte F, Heinrich F, Peine S, Schulze Zur Wiesch J, Brehm T, Addo M, Lütgehetmann M, Altfeld M
EUR J IMMUNOL. 2022;52(8):1297-1307.
Humoral and Cellular Immune Response After Third and Fourth SARS-CoV-2 mRNA Vaccination in Liver Transplant Recipients
Harberts A, Schaub G, Ruether D, Duengelhoef P, Brehm T, Karsten H, Fathi A, Jahnke-Triankowski J, Fischer L, Addo M, Haag F, Lütgehetmann M, Lohse A, Schulze zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(11):2558-2566.e5.
Respiratory muscle dysfunction in long-COVID patients
Hennigs J, Huwe M, Hennigs A, Oqueka T, Simon M, Harbaum L, Körbelin J, Schmiedel S, Schulze Zur Wiesch J, Addo M, Kluge S, Klose H
INFECTION. 2022;50(5):1391-1397.
Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection
Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo M, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A
CELL REP MED. 2022;3(9):.
Die COVID-19-Pandemie – ein epochales Ereignis
Janssens U, Addo M, von Bergwelt-Baildon M
DEUT MED WOCHENSCHR. 2022;147(20):1297-1298.
Erratum: Die COVID-19-Pandemie – ein epochales Ereignis
Janssens U, Addo M, von Bergwelt-Baildon M
DEUT MED WOCHENSCHR. 2022;147(20):e114.
High-resolution analysis of individual spike peptide-specific CD4+ T-cell responses in vaccine recipients and COVID-19 patients
Karsten H, Cords L, Westphal T, Knapp M, Brehm T, Hermanussen L, Omansen T, Schmiedel S, Woost R, Ditt V, Peine S, Lütgehetmann M, Huber S, Ackermann C, Wittner M, Addo M, Sette A, Sidney J, Schulze Zur Wiesch J
CLIN TRANSL IMMUNOL. 2022;11(8):.
Eine Erhebung zum Impfstatus von COVID-19-Patienten auf Normal- und Intensivstationen in Hamburg
Kluge S, Jarczak D, Eberhardt R, Herrlinger K, Janneck M, Borlich O, Weber C, Schley J, Emami P, Bergmann M, Addo M, Kerner T
DEUT MED WOCHENSCHR. 2022;147(8):492-494.
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Koll C, Hopff S, Meurers T, Lee C, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, Mitrov L, Frank S, Miljukov O, Erber J, Hellmuth J, Reese J, Steinbeis F, Bahmer T, Hagen M, Meybohm P, Hansch S, Vadász I, Krist L, Jiru-Hillmann S, Prasser F, Vehreschild J
SCI DATA. 2022;9(1):.
SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia
Mellinghoff S, Mayer L, Robrecht S, Weskamm L, Dahlke C, Gruell H, Schlotz M, Vanshylla K, Schloser H, Thelen M, Fink A, Fischer K, Klein F, Addo M, Eichhorst B, Hallek M, Langerbeins P
HAEMATOLOGICA. 2022;107(10):2480-2484.
SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia
Mellinghoff S, Robrecht S, Mayer L, Weskamm L, Dahlke C, Gruell H, Vanshylla K, Schlösser H, Thelen M, Fink A, Fischer K, Klein F, Addo M, Eichhorst B, Hallek M, Langerbeins P
LEUKEMIA. 2022;36(2):562-565.
Debunking Misinformation and Communicating Critical Events in Vaccine Trials: Experimental Evidence on Vaccination Intentions in SARS-CoV-2 Pandemic
Memenga P, Eitze S, Shamsrizi P, Addo M, Betsch C
European Journal of Health Communication. 2022;3(2):64-96.
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
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EMERG INFECT DIS. 2022;28(9):1765-1769.
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DTSCH ARZTEBL INT. 2022;119(35-36):607-608.
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The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics
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Erratum zu: Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik : Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze Zur Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2022;65(3):398.
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NAT METAB. 2022;4(3):310-319.
Flow cytometric protocol to characterize human memory B cells directed against SARS-CoV-2 spike protein antigens
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MOL THER-METH CLIN D. 2021;23:418-423.
Patient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020
Brehm T, Heyer A, Roedl K, Jarczak D, Nierhaus A, Nentwich M, van der Meirschen M, Schultze A, Christner M, Fiedler W, Kröger N, Huber T, Klose H, Sterneck M, Jordan S, Kreuels B, Schmiedel S, Addo M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
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SCI REP-UK. 2021;11(1):.
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Weniger ist mehr … in der Infektiologie
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INTERNIST. 2021;62(4):373-378.
A call to caution when hydroxychloroquine is given to elderly patients with COVID-19
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FRONT NEUROL. 2021;12:632535.
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A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein
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IMMUN INFLAMM DIS. 2021;9(3):905-917.
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J TROP PEDIATRICS. 2021;67(1):fmaa135.
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ADV EXP MED BIOL. 2021;1318:549-573.
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Infektionen und Gesellschaft
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Case Report - Clinical Management of a Patient With Metastatic Non-Small Cell Lung Cancer Newly Receiving Immune Checkpoint Inhibition During Symptomatic COVID-19
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TIPS and splenorenal shunt for complications of portal hypertension in chronic hepatosplenic schistosomiasis-A case series and review of the literature
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Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General
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Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs
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Less than you'd think-a prospective study on MRSA-colonization in healthy travellers
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Update 2021: COVID-19 aus Sicht der internistischen Schwerpunkte
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B cell analysis in SARS‐CoV‐2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID‐19
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J LEUKOCYTE BIOL. 2021;109(1):77-90.
Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
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Risk factors for different intestinal pathogens among patients with traveler's diarrhea: A retrospective analysis at a German travel clinic (2009-2017)
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Distinct early IgA profile may determine severity of COVID-19 symptoms: an immunological case series
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Usp18 Expression in CD169+ Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV
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Heidepriem J, Krähling V, Dahlke C, Wolf T, Klein F, Addo M, Becker S, Loeffler F
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Relapsing cutaneous leishmaniasis in a patient requiring TNF-α-inhibitor Infliximab for Takayasu-arteritis: Case report and review of the literature
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Significance of Anti-Nuclear Antibodies and Cryoglobulins in Patients with Acute and Chronic HEV Infection
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PATHOGENS. 2020;9(9):.
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Scent dog identification of samples from COVID-19 patients - a pilot study
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BMC INFECT DIS. 2020;20(1):536.
Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101)
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Ebola Virus Disease Survivors Show More Efficient Antibody Immunity than Vaccinees Despite Similar Levels of Circulating Immunoglobulins
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Von den Toten lernen - neue Erkenntnisse zu Covid-19
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Integration of microarray data and literature mining identifies a sex bias in DPP4+CD4+ T cells in HIV-1 infection
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Ehrhardt S, Zehner M, Krähling V, Cohen-Dvashi H, Kreer C, Elad N, Gruell H, Ercanoglu M, Schommers P, Gieselmann L, Eggeling R, Dahlke C, Wolf T, Pfeifer N, Addo M, Diskin R, Becker S, Klein F
NAT MED. 2019;25(10):1589-1600.
Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens
Fathi A, Dahlke C, Addo M
HUM VACC IMMUNOTHER. 2019;15(10):2269-2285.
Brain magnetic resonance imaging in imported malaria
Frölich A, Tober-Lau P, Schönfeld M, Brehm T, Kurth F, Vinnemeier C, Addo M, Fiehler J, Rolling T
MALARIA J. 2019;18(1):74.
Rezidivierendes Erbrechen und Kopfschmerzen bei einem 26-jährigen Patienten
Heinemann M, Galaski J, Mager A, Ittrich H, Addo M, Jordan S
INTERNIST. 2019;60(7):756-760.
Transjugular Intrahepatic Portosystemic Shunt (TIPS) for primary and secondary prophylaxis of variceal bleeding in hepatic schistosomiasis
Kraef C, Arand J, Galaski J, Jordan S, Kluwe J, Lohse A, Addo M, Ramharter M, Schmiedel S
TRAVEL MED INFECT DI. 2019;30:130-132.
Management der saisonalen Influenza 2017/2018: Erfahrungen an einem deutschen Universitätsklinikum
Kraef C, van der Meirschen M, Wichmann D, Kutza M, Restemeyer C, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
BUNDESGESUNDHEITSBLA. 2019;62(7):870-880.
Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans
Poetsch J, Dahlke C, Zinser M, Kasonta R, Lunemann S, Rechtien A, Ly M, Stubbe H, Krähling V, Biedenkopf N, Eickmann M, Fehling S, Olearo F, Strecker T, Sharma P, Lang K, Lohse A, Schmiedel S, Becker S, Addo M
J INFECT DIS. 2019;219(4):556-561.
Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)
Schäfer G, Hoffmann C, Arasteh K, Schürmann D, Stephan C, Jensen B, Stoll M, Bogner J, Faetkenheuer G, Rockstroh J, Klinker H, Härter G, Stöhr A, Degen O, Bibiza-Freiwald E, Hüfner A, Jordan S, Schulze Zur Wiesch J, Addo M, Lohse A, van Lunzen J, Schmiedel S
AIDS RES THER. 2019;16(1):34.
Determinants of post-malarial anemia in African children treated with parenteral artesunate
Scheu K, Adegnika A, Addo M, Ansong D, Cramer J, Fürst S, Kremsner P, Kurth F, Jacobs T, May J, Ramharter M, Sylverken J, Vinnemeier C, Agbenyega T, Rolling T
SCI REP-UK. 2019;9(1):18134.
Author Correction: Differential expression pattern of co-inhibitory molecules on CD4 T cells in uncomplicated versus complicated malaria.
Abel A, Steeg C, Aminkiah F, Addai-Mensah O, Addo M, Gagliani N, Casar C, Yar D, Owusu-Dabo E, Jacobs T, Mackroth M
SCI REP-UK. 2018;8(1):17587.
Differential expression pattern of co-inhibitory molecules on CD4(+) T cells in uncomplicated versus complicated malaria
Abel A, Steeg C, Aminkiah F, Addai-Mensah O, Addo M, Gagliani N, Casar C, Yar D, Owusu-Dabo E, Jacobs T, Mackroth M
SCI REP-UK. 2018;8(1):4789.
Ist die Welt ausreichend gerüstet für das nächste unbekannte Virus?
Addo M
Frankfurter Allgemeine Zeitung. 2018.
Tuberculous Tenosynovitis
Brehm T, Schmiedel S, Addo M
DTSCH ARZTEBL INT. 2018;115(42):714.
Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center.
Brehm T, Schulze zur Wiesch J, Lütgehetmann M, Tappe D, Eisermann P, Lohse A, Addo M, Schmiedel S
INFECTION. 2018;46(6):847-853.
Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV
Fischer T, Spohn M, Olearo F, Zinser M, Kasonta R, Stubbe H, Rechtien A, Ly M, Schmiedel S, Lohse A, Grundhoff A, Addo M, Dahlke C
VACCINE. 2018;36(46):7083-7094.
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study
Huttner A, Agnandji S, Combescure C, Fernandes J, Bache E, Kabwende L, Ndungu F, Brosnahan J, Monath T, Lemaître B, Grillet S, Botto M, Engler O, Portmann J, Siegrist D, Bejon P, Silvera P, Kremsner P, Siegrist C
LANCET INFECT DIS. 2018;18(7):738-748.
HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients
Westhölter D, Hiller J, Denzer U, Polywka S, Ayuk F, Rybczynski M, Horvatits T, Gundlach S, Blöcker J, Schulze Zur Wiesch J, Fischer N, Addo M, Peine S, Göke B, Lohse A, Lütgehetmann M, Pischke S
J HEPATOL. 2018;69(1):36-42.
Ebola-Impfstoff-Entwicklung: Im Krisenfall schnell, aber mit hohem Sicherheitsanspruch
Zinser M, Borregaard S, Dahlke C, Addo M
DTSCH ARZTEBL INT. 2018;115(Supplement: Perspektiven der Infektiologie):27-28.
Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells
Angin M, Fathi A, King M, Ledoux M, Piechocka-Trocha A, Altfeld M, Addo M
AIDS. 2017;31(5):635-641.
Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Dahlke C, Kasonta R, Lunemann S, Krähling V, Zinser M, Biedenkopf N, Fehling S, Ly M, Rechtien A, Stubbe H, Olearo F, Borregaard S, Jambrecina A, Stahl F, Strecker T, Eickmann M, Lütgehetmann M, Spohn M, Schmiedel S, Lohse A, Becker S, Addo M
EBIOMEDICINE. 2017;19:107-118.
Comprehensive characterization of cellular immune responses following Ebola virus infection
Dahlke C, Lunemann S, Kasonta R, Kreuels B, Schmiedel S, Ly M, Fehling S, Strecker T, Becker S, Altfeld M, Sow A, Lohse A, Muñoz-Fontela C, Addo M
J INFECT DIS. 2017;215(2):287-292.
Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV
Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, Kasonta R, Zinser M, Stubbe H, Matschl U, Lohse A, Krähling V, Eickmann M, Becker S, Thiébaut R, Altfeld M, Addo M
CELL REP. 2017;20(9):2251-2261.
Pre-travel advice at a crossroad: Medical preparedness of travellers to South and Southeast-Asia - The Hamburg Airport Survey
Rolling T, Mühlenpfordt M, Addo M, Cramer J, Vinnemeier C
TRAVEL MED INFECT DI. 2017;18:41-45.
Helminthic infections in returning travelers and migrants with eosinophilia: Diagnostic value of medical history, eosinophil count and IgE
Salzer H, Rolling T, Vinnemeier C, Tannich E, Schmiedel S, Addo M, Cramer J
TRAVEL MED INFECT DI. 2017;20:49-55.
Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study
Vinnemeier C, Rothe C, Kreuels B, Addo M, Vygen-Bonnet S, Cramer J, Rolling T
MALARIA J. 2017;16(1):44.
Viren überlisten: Globale Virusinfektionen werden beherrschbar - aber neue Gefahren drohen
Addo M, Lohse A
2016. Erkenntnis, Wissenschaft und Gesellschaft. Buchmüller W, Jakobeit C (Hrsg.). 1. Aufl. Springer-Verlag GmbH and Co. KG, 101-118.
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Agnandji S, Huttner A, Zinser M, Njuguna P, Dahlke C, Fernandes J, Yerly S, Dayer J, Kraehling V, Kasonta R, Adegnika A, Altfeld M, Auderset F, Bache E, Biedenkopf N, Borregaard S, Brosnahan J, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling S, Finckh A, Goncalves A, Grobusch M, Hooper J, Jambrecina A, Kabwende A, Kaya G, Kimani D, Lell B, Lemaître B, Lohse A, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl F, Staines H, Strecker T, Stubbe H, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny M, Bejon P, Kremsner P, Addo M, Siegrist C
NEW ENGL J MED. 2016;374(17):1647-60.
Molecular Diagnosis of Human Taenia martis Eye Infection
Koch T, Schoen C, Muntau B, Addo M, Ostertag H, Wiechens B, Tappe D
AM J TROP MED HYG. 2016;94(5):1055-7.
Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study
Lehmann M, Brünahl C, Addo M, Becker S, Schmiedel S, Lohse A, Schramm C, Löwe B
J PSYCHOSOM RES. 2016;83:69-74.
Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi
Mackroth M, Tappe D, Tannich E, Addo M, Rothe C
OPEN FORUM INFECT DI. 2016;3(1):ofw039.
Sharp increase of imported Plasmodium vivax malaria seen in migrants from Eritrea in Hamburg, Germany
Roggelin L, Tappe D, Noack B, Addo M, Tannich E, Rothe C
MALARIA J. 2016;2016(15):325.
Unique human immune signature of Ebola virus disease in Guinea
Ruibal P, Oestereich L, Lüdtke A, Becker-Ziaja B, Wozniak D, Kerber R, Korva M, Cabeza-Cabrerizo M, Bore J, Koundouno F, Duraffour S, Weller R, Thorenz A, Cimini E, Viola D, Agrati C, Repits J, Afrough B, Cowley L, Ngabo D, Hinzmann J, Mertens M, Vitoriano I, Logue C, Boettcher J, Pallasch E, Sachse A, Bah A, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng E, García-Dorival I, Wölfel R, Stoecker K, Fleischmann E, Strecker T, Di Caro A, Avšič-Županc T, Kurth A, Meschi S, Mély S, Newman E, Bocquin A, Kis Z, Kelterbaum A, Molkenthin P, Carletti F, Portmann J, Wolff S, Castilletti C, Schudt G, Fizet A, Ottowell L, Herker E, Jacobs T, Kretschmer B, Severi E, Ouedraogo N, Lago M, Negredo A, Franco L, Anda P, Schmiedel S, Kreuels B, Wichmann D, Addo M, Lohse A, De Clerck H, Nanclares C, Jonckheere S, Van Herp M, Sprecher A, Xiaojiang G, Carrington M, Miranda O, Castro C, Gabriel M, Drury P, Formenty P, Diallo B, Koivogui L, Magassouba N, Carroll M, Günther S, Muñoz-Fontela C
NATURE. 2016;533(7601):100-4.
Medizinische Versorgung von Flüchtlingen: Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Addo M, Lohse A, Schmiedel S
DEUT MED WOCHENSCHR. 2016;141(1):34-37.
Medizinische Versorgung von Flüchtlingen – Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Roggelin L, Kreuels B, Rothe C, Addo M, Lohse A, Schulze zur Wiesch J, Schmiedel S
FLUGMEDIZIN TROPENME. 2016;23(1):45-49.
Tropheryma whipplei in children with diarrhoea in rural Ghana
Vinnemeier C, Klupp E, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo M, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer J, May J, Tannich E
CLIN MICROBIOL INFEC. 2016;22(1):65.e1 - 65.e3.
Geschlechtsunterschiede bei Infektionserkrankungen
Beisel C, Lunzen J, Lohse A, Addo M, Altfeld M
DEUT MED WOCHENSCHR. 2015;140(18):1385-90.
Comparison of autochthonous and imported cases of hepatitis A or hepatitis E
Hartl J, Kreuels B, Polywka S, Addo M, Lütgehetmann M, Dandri-Petersen M, Dammermann W, Sterneck M, Lohse A, Pischke S
Z GASTROENTEROL. 2015;53(7):639-643.
Severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Addo M, Schmiedel S
NEW ENGL J MED. 2015;372(14):1377.
Ebola and psychological stress of health care professionals
Lehmann M, Brünahl C, Löwe B, Addo M, Schmiedel S, Lohse A, Schramm C
EMERG INFECT DIS. 2015;21(5):913-914.
Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients
Sada-Ovalle I, Ocaña-Guzman R, Pérez-Patrigeón S, Chávez-Galán L, Sierra-Madero J, Torre-Bouscoulet L, Addo M, Addo M
J INT AIDS SOC. 2015;18(1):20078.
Ex vivo cytosolic delivery of functional macromolecules to immune cells
Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos G, Eyerman A, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan O, Addo M, von Andrian U, Anderson D, Langer R, Lieberman J, Jensen K
PLOS ONE. 2015;10(4):e0118803.
Sex-based differences in HIV type 1 pathogenesis
Addo M, Altfeld M
J INFECT DIS. 2014;209 Suppl 3(Suppl 3):S86-92.
Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity
Angin M, Klarenbeek P, King M, Sharma S, Moodley E, Rezai A, Piechocka-Trocha A, Toth I, Chan A, Goulder P, Ndung'u T, Kwon D, Addo M
PLOS ONE. 2014;9(2):e86920.
HIV-1 infection impairs regulatory T-cell suppressive capacity on a per-cell basis
Angin M, Sharma S, King M, Murooka T, Ghebremichael M, Mempel T, Walker B, Bhasin M, Addo M
J INFECT DIS. 2014;210(6):899-903.
A dead-end host: is there a way out? A position piece on the ebola virus outbreak by the international union of immunology societies
Gray C, Addo M, Schmidt R
FRONT IMMUNOL. 2014;5:562.
A case of severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse A, Addo M, Schmiedel S
NEW ENGL J MED. 2014;371(25):2394-401.
New tools to expand regulatory T cells from HIV-1-infected individuals
Angin M, King M, Addo M
JOVE-J VIS EXP. 2013;(75):e50244.
Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection
Jost S, Moreno-Nieves U, Garcia-Beltran W, Rands K, Reardon J, Toth I, Piechocka-Trocha A, Altfeld M, Addo M
RETROVIROLOGY. 2013;10:74.
Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection
Vaidya S, Streeck H, Beckwith N, Ghebremichael M, Pereyra F, Kwon D, Addo M, Rychert J, Routy J, Jessen H, Kelleher A, Hecht F, Sekaly R, Carrington M, Walker B, Allen T, Rosenberg E, Altfeld M
RETROVIROLOGY. 2013;10:139.
Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers.
Angin M, King M, Altfeld M, Walker B, Wucherpfennig K, Addo M
AIDS. 2012;26(16):2112-2115.
Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.
Angin M, Kwon D, Streeck H, Wen F, King M, Rezai A, Law K, Hongo T, Pyo A, Piechocka-Trocha A, Toth I, Pereyra F, Ghebremichael M, Rodig S, Milner D, Richter J, Altfeld M, Kaufmann D, Walker B, Addo M
J INFECT DIS. 2012;205(10):1495-1500.
Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses.
Angin M, Streeck H, Wen F, King M, Pereyra F, Altfeld M, Walker B, Addo M
AIDS RES HUM RETROV. 2012;28(8):749-751.
Primary HIV-1 infection is associated with increased plasma levels of heme-oxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells.
Fathi A, Angin M, King M, Piechocka-Trocha A, Altfeld M, Walker B, Addo M
2012. 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, USA. .
CD4+ CD25+ regulatory T cells impair HIV-1-specific CD4 T cell responses by upregulating interleukin-10 production in monocytes.
Kwon D, Angin M, Hongo T, Law K, Johnson J, Porichis F, Hart M, Pavlik D, Tighe D, Kavanagh D, Streeck H, Addo M, Kaufmann D
J VIROL. 2012;86(12):6586-6594.
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.
Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield E, Sobel R, Okada H, McKinnon P, Mak T, Addo M, Anderson A, Kuchroo V
NAT MED. 2012;18(9):1394-1400.
Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals.
Addo M, Altfeld M, Brainard D, Rathod A, Piechocka-Trocha A, Fideli U, Mulenga J, Shutes E, Alvino D, Hunter E, Allen S, Walker B
J INFECT DIS. 2011;203(2):258-262.
Increased plasma levels of hemoxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells in acute HIV-1 infection
Angin M, Fathi A, King M, Addo M
2011. AIDS Vaccine Conference 2011, Bangkok, Thailand. .
Impact of heme oxygenase-1 specific CD8+ regulatory T cells on HIV-1 immunity
Fathi A, Angin M, King M, Addo M
2011. Scientific Advisory Committee 2011 Poster Session, Massachusetts General Hospital, Boston, MA, USA. .
Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.
Julg B, Pereyra F, Buzón M, Piechocka-Trocha A, Clark M, Baker B, Lian J, Miura T, Martinez-Picado J, Addo M, Walker B
CLIN INFECT DIS. 2010;51(2):233-238.
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Study I, Pereyra F, Jia X, McLaren P, Telenti A, Bakker d, Paul I, Walker B, Ripke S, Brumme C, Pulit S, Carrington M, Kadie C, Carlson J, Heckerman D, Graham R, Plenge R, Deeks S, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore J, Beattie N, Gupta S, Crenshaw A, Burtt N, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss K, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino D, Addo M, Addo M, Allen T, Altfeld M, Henn M, Sylvie L, Streeck H, Haas D, Kuritzkes D, Robbins G, Shafer R, Gulick R, Shikuma C, Haubrich R, Riddler S, Sax P, Daar E, Ribaudo H, Agan B, Agarwal S, Ahern R, Allen B, Altidor S, Altschuler E, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos N, Benson A, Berger J, Bernard N, Bernard A, Birch C, Bodner S, Bolan R, Boudreaux E, Bradley M, Braun J, Brndjar J, Brown S, Brown K, Brown S, Burack J, Bush L, Cafaro V, Campbell O, Campbell J, Carlson R, Carmichael J, Casey K, Cavacuiti C, Celestin G, Chambers S, Chez N, Chirch L, Cimoch P, Cohen D, Cohn L, Conway B, Cooper D, Cornelson B, Cox D, Cristofano M, Cuchural G, Czartoski J, Dahman J, Daly J, Davis B, Davis K, Davod S, DeJesus E, Dietz C, Dunham E, Dunn M, Ellerin T, Eron J, Fangman J, Farel C, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg K, French N, Fuchs J, Fuller J, Gaberman J, Gallant J, Gandhi R, Garcia E, Garmon D, Gathe J, Gaultier C, Gebre W, Gilman F, Gilson I, Goepfert P, Gottlieb M, Goulston C, Groger R, Gurley T, Haber S, Hardwicke R, Hardy W, Harrigan P, Hawkins T, Heath S, Hecht F, Henry W, Hladek M, Hoffman R, Horton J, Hsu R, Huhn G, Hunt P, Hupert M, Illeman M, Jaeger H, Jellinger R, John M, Johnson J, Johnson K, Johnson H, Johnson K, Joly J, Jordan W, Kauffman C, Khanlou H, Killian R, Kim A, Kim D, Kinder C, Kirchner J, Kogelman L, Kojic E, Korthuis P, Kurisu W, Kwon D, LaMar M, Lampiris H, Lanzafame M, Lederman M, Lee D, Lee J, Lee M, Lee E, Lemoine J, Levy J, Llibre J, Liguori M, Little S, Liu A, Lopez A, Loutfy M, Loy D, Mohammed D, Man A, Mansour M, Marconi V, Markowitz M, Marques R, Martin J, Martin H, Mayer K, McElrath M, McGhee T, McGovern B, McGowan K, McIntyre D, Mcleod G, Menezes P, Mesa G, Metroka C, Meyer-Olson D, Miller A, Montgomery K, Mounzer K, Nagami E, Nagin I, Nahass R, Nelson M, Nielsen C, Norene D, O'Connor D, Ojikutu B, Okulicz J, Oladehin O, Oldfield E, Olender S, Ostrowski M, Owen W, Pae E, Parsonnet J, Pavlatos A, Perlmutter A, Pierce M, Pincus J, Pisani L, Price L, Proia L, Prokesch [
SCIENCE. 2010;330(6010):1551-1557.
The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1
Kim A, Lauer G, Ouchi K, Addo M, Lucas M, Schulze Zur Wiesch J, Timm J, Boczanowski M, Duncan J, Wurcel A, Casson D, Chung R, Draenert R, Klenerman P, Walker B
BLOOD. 2005;105(3):1170-8.
Vpr is preferentially targeted by CTL during HIV-1 infection
J IMMUNOL. 2001;167(5):2743-52.
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals
Addo M, Altfeld M, Rosenberg E, Eldridge R, Philips M, Habeeb K, Khatri A, Brander C, Robbins G, Mazzara G, Goulder P, Walker B
P NATL ACAD SCI USA. 2001;98(4):1781-6.
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif
Altfeld M, Livingston B, Reshamwala N, Nguyen P, Addo M, Shea A, Newman M, Fikes J, Sidney J, Wentworth P, Chesnut R, Eldridge R, Rosenberg E, Robbins G, Brander C, Sax P, Boswell S, Flynn T, Buchbinder S, Goulder P, Walker B, Sette A, Kalams S
J VIROL. 2001;75(3):1301-11.
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
Altfeld M, Rosenberg E, Shankarappa R, Mukherjee J, Hecht F, Eldridge R, Addo M, Poon S, Phillips M, Robbins G, Sax P, Boswell S, Kahn J, Brander C, Goulder P, Levy J, Mullins J, Walker B
J EXP MED. 2001;193(2):169-80.
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays
Goulder P, Addo M, Altfeld M, Rosenberg E, Tang Y, Govender U, Mngqundaniso N, Annamalai K, Vogel T, Hammond M, Bunce M, Coovadia H, Walker B
J VIROL. 2001;75(3):1339-47.
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
Goulder P, Altfeld M, Rosenberg E, Nguyen T, Tang Y, Eldridge R, Addo M, He S, Mukherjee J, Phillips M, Bunce M, Kalams S, Sekaly R, Walker B, Brander C
J EXP MED. 2001;193(2):181-94.
Evolution and transmission of stable CTL escape mutations in HIV infection
Goulder P, Brander C, Tang Y, Tremblay C, Colbert R, Addo M, Rosenberg E, Nguyen T, Allen R, Trocha A, Altfeld M, He S, Bunce M, Funkhouser R, Pelton S, Burchett S, McIntosh K, Korber B, Walker B
NATURE. 2001;412(6844):334-8.
T(H)1 to T(H)2 shift of cytokines in peripheral blood of HIV-infected patients is detectable by reverse transcriptase polymerase chain reaction but not by enzyme-linked immunosorbent assay under nonstimulated conditions
Altfeld M, Addo M, Kreuzer K, Rockstroh J, Dumoulin F, Schliefer K, Leifeld L, Sauerbruch T, Spengler U
JAIDS-J ACQ IMM DEF. 2000;23(4):287-94.
Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay
Altfeld M, Trocha A, Eldridge R, Rosenberg E, Phillips M, Addo M, Sekaly R, Kalams S, Burchett S, McIntosh K, Walker B, Goulder P
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