KEY PUBLICATIONS
Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
U. Haferkamp, C. Hartmann, C. L. Abid, A. Brachner, A. Höchner, A. Gerhartl, B. Harwardt, S. Leckzik, J. Leu, M. Metzger, M. Nastainczyk-Wulf, W. Neuhaus, S. Oerter, O. Pless, D. Rujescu, M. Jung, A. Appelt-Menzel. Fluids and Barriers of the CNS 20(1):78 (2023)
Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity.
L. Binkle-Ladisch, A. Pironet, A. Zaliani, C. Alcouffe, D. Mensching, U. Haferkamp, A. Willing, M. S. Woo, A. Erdmann, T. Jessen, S. D. Hess, P. Gribbon, O. Pless, R. Vennekens, & M. A. Friese. iScience, 27(12), 111425 (2024)
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2.
K. Krasemann, U.* Haferkamp, S.* Pfefferle, M. S. Woo, F. Heinrich, M. Schweizer, A. Appelt-Menzel, A. Cubukova, J. Barenberg, J. Leu, K. Hartmann, E. Thies, J. L. Littau, D. Sepulveda-Falla, L. Zhang, K. Ton, Y. Liang, J. Matschke, F. Ricklefs, T. Sauvigny, J. Sperhake, A. Fitzek, A. Gerhartl, A. Brachner, N. Geiger, E. M. König, J. Bodem, S. Franzenburg, A. Franke, S Moese, F. J. Müller, G. Geisslinger, C. Claussen, A. Kannt, A. Zaliani, P. Gribbon, B. Ondruschka, W. Neuhaus, M. A. Friese, M. Glatzel, O. Pless (* equal contribution). Stem Cell Reports 17(2):307-320 (2022)
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