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Transgenic Core Facility
The mouse is the most important model organism to analyse the development and progression of human diseases and also investigate the influence of disease-triggering genetic factors. In addition, mouse models offer the opportunity to investigate innovative therapeutic approaches in the entire organism.
The Transgenic Core Facility (TCF) has the task of developing tailor-made new mouse models for the scientists at the University Medical Centre Hamburg-Eppendorf (UKE) and their collaborators. We use innovative and state-of-the-art genome engineering technologies, such as the powerful enzymatic technique known as CRISPR-Cas9.
The TCF is located at the Centre for Molecular Neurobiology Hamburg (ZMNH).
ANNE-MARIE MARZESCO
Head - Transgenic Core Facility
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