Publikationen der Arbeitsgruppe
2024
High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio
Bacmeister L, Goßling A, Buellesbach A, Birukov A, Myers J, Thomas S, Lee S, Andersen M, Jorgensen J, Diemert A, Blois S, Arck P, Hecher K, Herse F, Blankenberg S, Dechend R, Westermann D, Zeller T
CIRCULATION. 2024;149(2):95-106.
Placental glycosylation senses the anti-angiogenic milieu induced by human sFLT1 during pregnancy
Kirkgöz K, Vogtmann R, Xie Y, Zhao F, Riedel A, Adam L, Freitag N, Harms C, Garcia M, Plösch T, Gellhaus A, Blois S
J REPROD IMMUNOL. 2024;164:.
Dissecting humoral immune responses to an MVA-vectored MERS-CoV vaccine in humans using a systems serology approach
Weskamm L, Tarnow P, Harms C, Huchon M, Raadsen M, Friedrich M, Rübenacker L, Grüttner C, Garcia M, Koch T, Becker S, Sutter G, Lhomme E, Haagmans B, Fathi A, Blois S, Dahlke C, Richert L, Addo M
ISCIENCE. 2024;27(8):110470.
Fetal growth restriction induced by maternal gal-3 deficiency is associated with altered gut-placenta axis
Xie Y, Zhao F, Wang Y, Borowski S, Freitag N, Tirado-Gonzalez I, Hofsink N, Matschl U, Plösch T, Garcia M, Blois S
CELL DEATH DIS. 2024;15(8):.
2023
Maternal-derived galectin-1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia
Xie Y, Zhao F, Freitag N, Borowski S, Wang Y, Harms C, Pang P, Desforges J, Wen T, Schwedhelm E, Singh M, Dechend R, Dell A, Haslam S, Dveksler G, Garcia M, Blois S
PNAS nexus. 2023;2(8):.
A unique maternal and placental galectin signature upon SARS-CoV-2 infection suggests galectin-1 as a key alarmin at the maternal-fetal interface
Zhao F, Tallarek A, Wang Y, Xie Y, Diemert A, Lu-Culligan A, Vijayakumar P, Kittmann E, Urbschat C, Bayo J, Arck P, Farhadian S, Dveksler G, Garcia M, Blois S
FRONT IMMUNOL. 2023;14:1196395.
2022
Editorial: The placenta, fetomaternal tolerance and beyond: A tribute to Sir Peter Medawar on the 60th anniversary of his Nobel Prize
Barrientos G, Solano M, Blois S, Sharma S
FRONT IMMUNOL. 2022;13:.
Examination of the Contributions of Maternal/Placental-Derived Galectin-1 to Pregnancy Outcome
Borowski S, Freitag N, Urban I, Michel G, Barrientos G, Blois S
2022. Galectins. Stowell S, Arthur C, Cummings R (Hrsg.). 1. Aufl. New York, NY: Humana Press, 603-619.
Soluble CD146 is increased in preeclampsia and interacts with galectin-1 to regulate trophoblast migration through VEGFR2 receptor
Bouvier S, Traboulsi W, Blois S, Demattei C, Joshkon A, Mousty E, Nollet M, Paulmyer-Lacroix O, Foucault-Bertaud A, Fortier M, Leroyer A, Bachelier R, Letouzey V, Alfaidy N, Dignat-George F, Blot-Chabaud M, Gris J, Bardin N
F&S science. 2022;3(1):84-94.
2021
Acceleration of TAA-Induced Liver Fibrosis by Stress Exposure Is Associated with Upregulation of Nerve Growth Factor and Glycopattern Deviations
Atorrasagasti C, Piccioni F, Borowski S, Tirado-González I, Freitag N, Cantero M, Bayo J, Mazzolini G, Alaniz L, Blois S, Garcia M
INT J MOL SCI. 2021;22(10):.
Placental Glycoredox Dysregulation Associated with Disease Progression in an Animal Model of Superimposed Preeclampsia
Blois S, Prince P, Borowski S, Galleano M, Barrientos G
CELLS-BASEL. 2021;10(4):.
Phenotyping placental oxygenation in Lgals1 deficient mice using 19F MRI
Boehm-Sturm P, Mueller S, Freitag N, Borowski S, Foddis M, Koch S, Temme S, Flögel U, Blois S
SCI REP-UK. 2021;11(1):2126.
Galectin-Levels Are Elevated in Infants Born Preterm Due to Amniotic Infection and Rapidly Decline in the Neonatal Period
Faust K, Freitag N, Barrientos G, Hartel C, Blois S
FRONT IMMUNOL. 2021;11:.
Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models
Freitag N, Xie Y, Adam L, Borowski S, Blois S, Barrientos G
AM J REPROD IMMUNOL. 2021;86(6):e13491.
Targeted disruption of galectin 3 in mice delays the first wave of spermatogenesis and increases germ cell apoptosis
Lei T, Blois S, Freitag N, Bergmann M, Bhushan S, Wahle E, Huang A, Chen H, Hartmann M, Wudy S, Liu F, Meinhardt A, Fijak M
CELL MOL LIFE SCI. 2021;78(7):3621-3635.
Medawar's PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation
Menkhorst E, Than N, Jeschke U, Barrientos G, Szereday L, Dveksler G, Blois S
FRONT IMMUNOL. 2021;12:.
Immunobiology of Gestational Diabetes Mellitus in Post-Medawar Era
Sharma S, Banerjee S, Krueger P, Blois S
FRONT IMMUNOL. 2021;12:.
2020
Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)
Blois S, Verlohren S, Wu G, Clark G, Dell A, Haslam S, Barrientos G
SEMIN IMMUNOPATHOL. 2020;42(4):469-486.
Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics
Borowski S, Tirado-Gonzalez I, Freitag N, Garcia M, Barrientos G, Blois S
FRONT IMMUNOL. 2020;11:1316.
The chimera-type galectin-3 is a positive modulator of trophoblast functions with dysregulated expression in gestational diabetes mellitus
Freitag N, Tirado-González I, Barrientos G, Cohen M, Daher S, Goldman-Wohl D, Mincheva-Nilsson L, John C, Jeschke U, Blois S
AM J REPROD IMMUNOL. 2020;84(6):e13311.
Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency
Freitag N, Tirado-Gonzalez I, Barrientos G, Powell K, Boehm-Sturm P, Koch S, Hecher K, Staff A, Arck P, Diemert A, Blois S
CELL DEATH DIS. 2020;11(7):560.
Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand
Mendoza M, Lu D, Ballesteros A, Blois S, Abernathy K, Feng C, Dimitroff C, Zmuda J, Panico M, Dell A, Vasta G, Haslam S, Dveksler G
GLYCOBIOLOGY. 2020;30(11):895-909.
2019
Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins
Blois S, Dveksler G, Vasta G, Freitag N, Blanchard V, Barrientos G
FRONT IMMUNOL. 2019;10:1166.
Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions
Rattila S, Dunk C, Im M, Grichenko O, Zhou Y, Yanez-Mo M, Blois S, Yamada K, Erez O, Gomez-Lopez N, Lye S, Hinz B, Romero R, Cohen M, Dveksler G
CELLS-BASEL. 2019;8(11):.
2007
A pivotal role for galectin-1 in fetomaternal tolerance
Blois S, Ilarregui J, Tometten M, Garcia M, Orsal A, Cordo-Russo R, Toscano M, Bianco G, Kobelt P, Handjiski B, Tirado I, Markert U, Klapp B, Poirier F, Szekeres-Bartho J, Rabinovich G, Arck P
NAT MED. 2007;13(12):1450-7.
An impaired breeding phenotype in mice with a genetic deletion of beta-2 microglobulin and diminished MHC class I expression: role in reproductive fitness
Cooper J, Dealtry G, Ahmed M, Arck P, Klapp B, Blois S, Fernández N
BIOL REPROD. 2007;77(2):274-9.
High expression of survivin and down-regulation of Stat-3 characterize the feto-maternal interface in failing murine pregnancies during the implantation period
Garcia M, Tirado-Gonzalez I, Handjiski B, Tometten M, Orsal A, Hajos S, Fernández N, Arck P, Blois S
PLACENTA. 2007;28(7):650-7.
Neuroendocrine-immune disequilibrium and endometriosis: an interdisciplinary approach
Tariverdian N, Theoharides T, Siedentopf F, Gutiérrez G, Jeschke U, Rabinovich G, Blois S, Arck P
SEMIN IMMUNOPATHOL. 2007;29(2):193-210.
2006
The progesterone derivative dydrogesterone down-regulates neurokinin 1 receptor expression on lymphocytes, induces a Th2 skew and exerts hypoalgesic effects in mice
Orsal A, Blois S, Labuz D, Peters E, Schaefer M, Arck P
J MOL MED. 2006;84(2):159-67.
Prenatal stress enhances susceptibility of murine adult offspring toward airway inflammation
Pincus-Knackstedt M, Joachim R, Blois S, Douglas A, Orsal A, Klapp B, Wahn U, Hamelmann E, Arck P
J IMMUNOL. 2006;177(12):8484-92.
Nerve growth factor translates stress response and subsequent murine abortion via adhesion molecule-dependent pathways
Tometten M, Blois S, Kuhlmei A, Stretz A, Klapp B, Arck P
BIOL REPROD. 2006;74(4):674-83.
2005
Intercellular adhesion molecule-1/LFA-1 cross talk is a proximate mediator capable of disrupting immune integration and tolerance mechanism at the feto-maternal interface in murine pregnancies
Blois S, Tometten M, Kandil J, Hagen E, Klapp B, Margni R, Arck P
J IMMUNOL. 2005;174(4):1820-9.
2004
Lineage, maturity, and phenotype of uterine murine dendritic cells throughout gestation indicate a protective role in maintaining pregnancy
Blois S, Alba Soto C, Tometten M, Klapp B, Margni R, Arck P
BIOL REPROD. 2004;70(4):1018-23.
Depletion of CD8+ cells abolishes the pregnancy protective effect of progesterone substitution with dydrogesterone in mice by altering the Th1/Th2 cytokine profile
Blois S, Joachim R, Kandil J, Margni R, Tometten M, Klapp B, Arck P
J IMMUNOL. 2004;172(10):5893-9.
Letzte Aktualisierung aus dem FIS: 20.11.2024 - 23:32 Uhr