Illuminating the impact of γδ T cells in man and mice in spondylarthritides
Meyer A
EUR J IMMUNOL. 2024;54(10):e2451071.

Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes
You Y, Dunst J, Ye K, Sandoz P, Reinhardt A, Sandrock I, Comet N, Sarkar R, Yang E, Duprez E, Agudo J, Brown B, Utz P, Kastenmüller W, Gerlach C, Prinz I, Önfelt B, Kreslavsky T
NAT IMMUNOL. 2024;25(8):1367-1382.

Expansion of memory Vδ2 T cells following SARS-CoV-2 vaccination revealed by temporal single-cell transcriptomics
Terzoli S, Marzano P, Cazzetta V, Piazza R, Sandrock I, Ravens S, Tan L, Prinz I, Balin S, Calvi M, Carletti A, Cancellara A, Coianiz N, Franzese S, Frigo A, Voza A, Calcaterra F, Di Vito C, Della Bella S, Mikulak J, Mavilio D
NPJ VACCINES. 2024;9(1):63.

Guidelines for mouse and human DC functional assays
Clausen B, Amon L, Backer R, Berod L, Bopp T, Brand A, Burgdorf S, Chen L, Da M, Distler U, Dress R, Dudziak D, Dutertre C, Eich C, Gabele A, Geiger M, Ginhoux F, Giusiano L, Godoy G, Hamouda A, Hatscher L, Heger L, Heidkamp G, Hernandez L, Jacobi L, Kaszubowski T, Kong W, Lehmann C, Lopez Lopez T, Mahnke K, Nitsche D, Renkawitz J, Reza R, Saez P, Schlautmann L, Schmitt M, Seicher A, Sielaff M, Sparwasser T, Stoitzer P, Tchitashvili G, Tenzer S, Tochoedo N, Vurnek D, Zink F, Hieronymus T
EUR J IMMUNOL. 2023;53(12):e2249925.

Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression
Song Z, Henze L, Casar C, Schwinge D, Schramm C, Fuss J, Tan L, Prinz I
J LEUKOCYTE BIOL. 2023;114(6):630-638.

Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort
Grünhagel B, Borggrewe M, Hagen S, Ziegler S, Henseling F, Glau L, Thiele R, Pujantell M, Sivayoganathan V, Padoan B, Claussen J, Düsedau A, Hennesen J, Bunders M, Bonn S, Tolosa E, Krebs C, Dorn C, Altfeld M
ISCIENCE. 2023;26(11):108209.

RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery
Yang T, Barros-Martins J, Wang Z, Wencker M, Zhang J, Smout J, Gambhir P, Janssen A, Schimrock A, Georgiev H, León-Lara X, Weiss S, Huehn J, Prinz I, Krueger A, Foerster R, Walzer T, Ravens S
CELL REP. 2023;42(10):113230.

IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts
Picard F, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle P, Savai R, Prinz I, Waisman A, Moos S, Chang H, Heinrich S, Bartsch D, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung H, Mayer P, Gress T, Lauth M, Gaida M, Huber M
GUT. 2023;72(8):1510-1522.

IL-17 signaling in keratinocytes orchestrates the defense against Staphylococcus aureus skin infection
Moos S, Regen T, Wanke F, Tian Y, Arendholz L, Hauptmann J, Heinen A, Bleul L, Bier K, El Malki K, Reinhardt C, Prinz I, Diefenbach A, Wolz C, Schittek B, Waisman A, Kurschus F
J INVEST DERMATOL. 2023;143(7):1257-1267.e10.

Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller A, Zhao Y, Cicek H, Paust H, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber T, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs C, Neumann K
J AM SOC NEPHROL. 2023;34(6):1003-1018.

Antigen-specific γδ T cells contribute to cytomegalovirus control after stem cell transplantation
Prinz I, Koenecke C
CURR OPIN IMMUNOL. 2023;82:102303.

Individual Epitope-Specific CD8+ T Cell Immune Responses Are Shaped Differently during Chronic Viral Infection
Klein S, Mischke J, Beruldsen F, Prinz I, Antunes D, Cornberg M, Kraft A
PATHOGENS. 2023;12(5):.

Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
Deng L, Ly C, Abdollahi S, Zhao Y, Prinz I, Bonn S
FRONT IMMUNOL. 2023;14:1128326.

A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
Hahn A, Vogg L, Brey S, Schneider A, Schäfer S, Palmisano R, Pavlova A, Sandrock I, Tan L, Fichtner A, Prinz I, Ravens S, Winkler T
CELL REP. 2023;42(3):112253.

Characterization of Developmental Trajectories of Dendritic Cell Hematopoiesis Through Single-Cell RNA Sequencing Methods
Dress R, Ginhoux F
2023. Dendritic Cells. Sisirak V (eds.). 1. ed. New York, NY: Humana Press, 375-385.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory N, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt M, Bono M, Gagliani N, Sandrock I, Panzer U, Krebs C, Meyer-Schwesinger C, Prinz I, Mittrücker H
P NATL ACAD SCI USA. 2023;120(1):e2210490120.

Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination
Marzano P, Balin S, Terzoli S, Della Bella S, Cazzetta V, Piazza R, Sandrock I, Ravens S, Tan L, Prinz I, Calcaterra F, Di Vito C, Cancellara A, Calvi M, Carletti A, Franzese S, Frigo A, Darwish A, Voza A, Mikulak J, Mavilio D
FRONT IMMUNOL. 2023;14:1208662.

Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice
Gil-Pulido J, Amézaga N, Jorgacevic I, Manthey H, Rösch M, Brand T, Cidlinsky P, Schäfer S, Beilhack A, Saliba A, Lorenz K, Boon L, Prinz I, Waisman A, Korn T, Cochain C, Zernecke A
CARDIOVASC RES. 2022;118(14):2932-2945.

Cross-Reactive T Cell Response Exists in Chronic Lymphocytic Choriomeningitis Virus Infection upon Pichinde Virus Challenge
Mischke J, Klein S, Seamann A, Prinz I, Selin L, Ghersi D, Cornberg M, Kraft A
VIRUSES-BASEL. 2022;14(10):.

Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Ataide M, Knöpper K, Cruz de Casas P, Ugur M, Eickhoff S, Zou M, Shaikh H, Trivedi A, Grafen A, Yang T, Prinz I, Ohlsen K, Gomez de Agüero M, Beilhack A, Huehn J, Gaya M, Saliba A, Gasteiger G, Kastenmüller W
IMMUNITY. 2022;55(10):1813-1828.e9.

Corrigendum: Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng L, Harms A, Ravens S, Prinz I, Tan L
FRONT IMMUNOL. 2022;13:1055103.

OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells
Barros-Martins J, Bruni E, Fichtner A, Cornberg M, Prinz I
CYTOM PART A. 2022;101(10):856-861.

Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng L, Harms A, Ravens S, Prinz I, Tan L
FRONT IMMUNOL. 2022;13:.

Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Schneider J, Kuhlmann L, Xiao Y, Raha S, Bernhardt G, Stadler M, Thol F, Heuser M, Eder M, Ganser A, Ravens S, Förster R, Prinz I, Koenecke C, Schultze-Florey C
INT J MOL SCI. 2022;23(18):.

High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
Ritter K, Behrends J, Rückerl D, Hölscher A, Volz J, Prinz I, Hölscher C
CELLS-BASEL. 2022;11(18):.

A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR
Deseke M, Rampoldi F, Sandrock I, Borst E, Böning H, Ssebyatika G, Jürgens C, Plückebaum N, Beck M, Hassan A, Tan L, Demera A, Janssen A, Steinberger P, Koenecke C, Viejo-Borbolla A, Messerle M, Krey T, Prinz I
J EXP MED. 2022;219(9):.

Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8+ T Cells and Antitumor Immunity
Chen Y, Yan S, Pu Z, Feng J, Tan L, Li Y, Hu H, Huang W, Lin Y, Peng Z, He X, Huang F, Zhang H, Zhang Y
CANCER RES. 2022;82(17):3130-3142.

Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression
Bruni E, Cimino M, Donadon M, Carriero R, Terzoli S, Piazza R, Ravens S, Prinz I, Cazzetta V, Marzano P, Kunderfranco P, Peano C, Soldani C, Franceschini B, Colombo F, Garlanda C, Mantovani A, Torzilli G, Mikulak J, Mavilio D
J IMMUNOTHER CANCER. 2022;10(7):.

New insights on murine γδ T cells from single-cell multi-omics
Tan L, Inácio D, Prinz I, Silva-Santos B
SCI BULL. 2022;67(11):1102-1104.

γδ T cells license immature B cells to produce a broad range of polyreactive antibodies
Rampoldi F, Donato E, Ullrich L, Deseke M, Janssen A, Demera A, Sandrock I, Bubke A, Juergens A, Swallow M, Sparwasser T, Falk C, Tan L, Trumpp A, Prinz I
CELL REP. 2022;39(8):.

IL-17A-producing γδT cells promote muscle regeneration in a microbiota-dependent manner
Mann A, Hanna B, Muñoz-Rojas A, Sandrock I, Prinz I, Benoist C, Mathis D
J EXP MED. 2022;219(5):.

γδ T Cells Differentially Regulate Bone Loss in Periodontitis Models
Barel O, Aizenbud Y, Tabib Y, Jaber Y, Leibovich A, Horev Y, Zubeidat K, Saba Y, Eli-Berchoer L, Heyman O, Wilensky A, Prinz I, Hovav A
J DENT RES. 2022;101(4):428-436.

Three Layers of Intestinal γδ T Cells Talk Different Languages With the Microbiota
Rampoldi F, Prinz I
FRONT IMMUNOL. 2022;13:.

Interleukin-17 is disease promoting in early stages and protective in late stages of experimental periodontitis
Wilharm A, Binz C, Sandrock I, Rampoldi F, Lienenklaus S, Blank E, Winkel A, Demera A, Hovav A, Stiesch M, Prinz I
PLOS ONE. 2022;17(3):.

γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release
Hu M, Golovchenko N, Burns G, Nair P, Kelly T, Agos J, Irani M, Soh W, Zeglinski M, Lemenze A, Bonder E, Sandrock I, Prinz I, Granville D, Keely S, Watson A, Edelblum K
GASTROENTEROLOGY. 2022;162(3):877-889.e7.

The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis
Dywicki J, Buitrago-Molina L, Noyan F, Davalos-Misslitz A, Hupa-Breier K, Lieber M, Hapke M, Schlue J, Falk C, Raha S, Prinz I, Koenecke C, Manns M, Wedemeyer H, Hardtke-Wolenski M, Jaeckel E
HEPATOL COMMUN. 2022;6(2):320-333.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J, Baumjohann D, Beccaria C, Bernardo D, Boardman D, Borger J, Böttcher C, Brockmann L, Burns M, Busch D, Cameron G, Cammarata I, Cassotta A, Chang Y, Chirdo F, Christakou E, Čičin-Šain L, Cook L, Corbett A, Cornelis R, Cosmi L, Davey M, De Biasi S, De Simone G, Del Zotto G, Delacher M, Di Rosa F, Santo J, Diefenbach A, Dong J, Dörner T, Dress R, Dutertre C, Eckle S, Eede P, Evrard M, Falk C, Feuerer M, Fillatreau S, Fiz-Lopez A, Follo M, Foulds G, Fröbel J, Gagliani N, Galletti G, Gangaev A, Garbi N, Garrote J, Geginat J, Gherardin N, Gibellini L, Ginhoux F, Godfrey D, Gruarin P, Haftmann C, Hansmann L, Harpur C, Hayday A, Heine G, Hernández D, Herrmann M, Hoelsken O, Huang Q, Huber S, Huber J, Huehn J, Hundemer M, Hwang W, Iannacone M, Ivison S, Jäck H, Jani P, Keller B, Kessler N, Ketelaars S, Knop L, Knopf J, Koay H, Kobow K, Kriegsmann K, Kristyanto H, Krueger A, Kuehne J, Kunze-Schumacher H, Kvistborg P, Kwok I, Latorre D, Lenz D, Levings M, Lino A, Liotta F, Long H, Lugli E, MacDonald K, Maggi L, Maini M, Mair F, Manta C, Manz R, Mashreghi M, Mazzoni A, McCluskey J, Mei H, Melchers F, Melzer S, Mielenz D, Monin L, Moretta L, Multhoff G, Muñoz L, Muñoz-Ruiz M, Muscate F, Natalini A, Neumann K, Ng L, Niedobitek A, Niemz J, Almeida L, Notarbartolo S, Ostendorf L, Pallett L, Patel A, Percin G, Peruzzi G, Pinti M, Pockley A, Pracht K, Prinz I, Pujol-Autonell I, Pulvirenti N, Quatrini L, Quinn K, Radbruch H, Rhys H, Rodrigo M, Romagnani C, Saggau C, Sakaguchi S, Sallusto F, Sanderink L, Sandrock I, Schauer C, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schober K, Schoen J, Schuh W, Schüler T, Schulz A, Schulz S, Schulze J, Simonetti S, Singh J, Sitnik K, Stark R, Starossom S, Stehle C, Szelinski F, Tan L, Tarnok A, Tornack J, Tree T, van Beek J, van de Veen W, van Gisbergen K, Vasco C, Verheyden N, von Borstel A, Ward-Hartstonge K, Warnatz K, Waskow C, Wiedemann A, Wilharm A, Wing J, Wirz O, Wittner J, Yang J, Yang J
EUR J IMMUNOL. 2021;51(12):2708-3145.

Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke M, Clausen B, Ludewig P, Vienhues J, Bedke T, Javidi E, Rissiek B, Jank L, Brockmann L, Sandrock I, Degenhardt K, Jander A, Roth V, Schädlich I, Prinz I, Flavell R, Kobayashi Y, Renné T, Gerloff C, Huber S, Magnus T, Gelderblom M
J NEUROINFLAMM. 2021;18(1):.

Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
Schultze-Florey C, Kuhlmann L, Raha S, Barros-Martins J, Odak I, Tan L, Xiao Y, Ravens S, Hambach L, Venturini L, Stadler M, Eder M, Thol F, Heuser M, Forster R, Ganser A, Prinz I, Koenecke C
BLOOD ADV. 2021;5(21):4485-4499.

αβ T cells replacing dermal and epidermal γδ T cells in Tcrd-/- mice express an MHC-independent TCR repertoire
Binz C, Bubke A, Sandrock I, Prinz I
EUR J IMMUNOL. 2021;51(11):2618-2632.

Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A
Ritter K, Behrends J, Erdmann H, Rousseau J, Hölscher A, Volz J, Prinz I, Lindenstrøm T, Hölscher C
J MOL MED. 2021;99(11):1585-1602.

Lack of gamma delta T cells ameliorates inflammatory response after acute intestinal ischemia reperfusion in mice
Funken D, Yu Y, Feng X, Imvised T, Gueler F, Prinz I, Madadi-Sanjani O, Ure B, Kuebler J, Klemann C
SCI REP-UK. 2021;11(1):18628.

Monocytes and macrophages in severe COVID-19 - friend, foe or both?
Dress R, Ginhoux F
IMMUNOL CELL BIOL. 2021;99(6):561-564.

A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan L, Fichtner A, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs C, Ravens S, Prinz I
SCI IMMUNOL. 2021;6(58):.

IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer's Patches of Mice
Ullrich L, Lueder Y, Juergens A, Wilharm A, Barros-Martins J, Bubke A, Demera A, Ikuta K, Patzer G, Janssen A, Sandrock I, Prinz I, Rampoldi F
FRONT IMMUNOL. 2021;12:.

Letzte Aktualisierung aus dem FIS: 18.12.2024 - 03:14 Uhr