2024

Structural Progression in Patients with Definite and Non-Definite Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Major Adverse Cardiac Events
Aljehani A, Baig S, Kew T, Kalla M, Sommerfeld L, Murukutla V, Fabritz L, Steeds R
BIOMEDICINES. 2024;12(2):.

Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study
Fabritz L, Chua W, Cardoso V, Al-Taie C, Borof K, Suling A, Krause L, Kany S, Magnussen C, Wegscheider K, Breithardt G, Crijns H, Camm A, Gkoutos G, Ellinor P, Goette A, Schotten U, Wienhues-Thelen U, Zeller T, Schnabel R, Zapf A, Kirchhof P
CARDIOVASC RES. 2024;120(8):855-868.

Multimodal characterization of dilated cardiomyopathy: Geno- And Phenotyping of PrImary Cardiomyopathy (GrAPHIC)
Keil L, Berisha F, Ritter S, Skibowski J, Subramanian H, Nikolaev V, Kubisch C, Woitschach R, Fabritz L, Twerenbold R, Blankenberg S, Weidemann S, Zeller T, Kirchhof P, Reichart D, Magnussen C
ESC HEART FAIL. 2024;11(1):541-549.

Overexpression of VEGFα as a biomarker of endothelial dysfunction in aortic tissue of α-GAL-Tg/KO mice and its upregulation in the serum of patients with Fabry’s disease
Lund N, Wieboldt H, Fischer L, Muschol N, Braun F, Huber T, Sorriento D, Iaccarino G, Muellerleile K, Tahir E, Adam G, Kirchhof P, Fabritz L, Patten M
FRONT CARDIOVASC MED. 2024;11(11):1355033.

Publisher Correction: High resolution optical mapping of cardiac electrophysiology in pre-clinical models
O'Shea C, Winter J, Kabir S, O'Reilly M, Wells S, Baines O, Sommerfeld L, Correia J, Lei M, Kirchhof P, Holmes A, Fabritz L, Rajpoot K, Pavlovic D
SCI DATA. 2024;11(1):93.

PITX2 deficiency leads to atrial mitochondrial dysfunction
Reyat J, Sommerfeld L, O'Reilly M, Roth Cardoso V, Thiemann E, Khan A, O'Shea C, Harder S, Müller C, Barlow J, Stapley R, Chua W, Kabir S, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem S, Winters J, Zeemering S, Morgan N, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos G, Lorenz K, Cuello F, Kirchhof P, Fabritz L
CARDIOVASC RES. 2024;120(15):1907-1923.

Safety and efficacy of long-term Sodium Channel Blocker therapy for Early Rhythm Control: The EAST-AFNET 4 trial
Rillig A, Eckardt L, Borof K, Camm A, Crijns H, Goette A, Breithardt G, Lemoine M, Metzner A, Rottner L, Schotten U, Vettorazzi E, Wegscheider K, Zapf A, Heidbuchel H, Willems S, Fabritz L, Schnabel R, Magnussen C, Kirchhof P
EUROPACE. 2024;26(6):.

Popeye-domain-containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5
Rinné S, Kiper A, Jacob R, Ortiz-Bonnin B, Schindler R, Fischer S, Komadowski M, deMartino E, Schäfer M, Cornelius T, Fabritz L, Helker C, Brand T, Decher N
ISCIENCE. 2024;27(5):109696.

2023

Characterisation of patients referred to a tertiary-level inherited cardiac condition clinic with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC).
Aljehani A, Kew T, Baig S, Cox H, Sommerfeld L, Ensam B, Kalla M, Steeds R, Fabritz L
BMC CARDIOVASC DISOR. 2023;23(1):14.

An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions
Chua W, Cardoso V, Guasch E, Sinner M, Al-Taie C, Brady P, Casadei B, Crijns H, Dudink E, Hatem S, Kääb S, Kastner P, Mont L, Nehaj F, Purmah Y, Reyat J, Schotten U, Sommerfeld L, Zeemering S, Ziegler A, Gkoutos G, Kirchhof P, Fabritz L
SCI REP-UK. 2023;13(1):16743.

Early rhythm-control therapy for atrial fibrillation in patients with a history of stroke: a subgroup analysis of the EAST-AFNET 4 trial
Jensen M, Suling A, Metzner A, Schnabel R, Borof K, Goette A, Haeusler K, Zapf A, Wegscheider K, Fabritz L, Diener H, Thomalla G, Kirchhof P
LANCET NEUROL. 2023;22(1):45-54.

Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial
Kany S, Al-Taie C, Roselli C, Pirruccello J, Borof K, Reinbold C, Suling A, Krause L, Reissmann B, Schnabel R, Zeller T, Zapf A, Wegscheider K, Fabritz L, Ellinor P, Kirchhof P
CARDIOVASC RES. 2023;119(9):1799-1810.

Pulmonary Vein Isolation by Pulsed-field Ablation Induces Less Neurocardiac Damage Than Cryoballoon Ablation
Lemoine M, Mencke C, Nies M, Obergassel J, Scherschel K, Wieboldt H, Schleberger R, My I, Rottner L, Moser J, Kany S, Wenzel J, Moser F, Dinshaw L, Münkler P, Reissmann B, Ouyang F, Meyer C, Blankenberg S, Zeller T, Fabritz L, Rillig A, Metzner A, Kirchhof P
CIRC-ARRHYTHMIA ELEC. 2023;16(4):e011598.

Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide
O’Reilly M, Sommerfeld L, O’Shea C, Broadway-Stringer S, Andaleeb S, Reyat J, Kabir S, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin B, Holmes A, Kirchhof P, Fabritz L
EUROPACE. 2023;25(3):1152-1161.

Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
Schnabel R, Marinelli E, Arbelo E, Boriani G, Boveda S, Buckley C, Camm A, Casadei B, Chua W, Dagres N, de Melis M, Desteghe L, Diederichsen S, Duncker D, Eckardt L, Eisert C, Engler D, Fabritz L, Freedman B, Gillet L, Goette A, Guasch E, Svendsen J, Hatem S, Haeusler K, Healey J, Heidbuchel H, Hindricks G, Hobbs F, Hübner T, Kotecha D, Krekler M, Leclercq C, Lewalter T, Lin H, Linz D, Lip G, Løchen M, Lucassen W, Malaczynska-Rajpold K, Massberg S, Merino J, Meyer R, Mont L, Myers M, Neubeck L, Niiranen T, Oeff M, Oldgren J, Potpara T, Psaroudakis G, Pürerfellner H, Ravens U, Rienstra M, Rivard L, Scherr D, Schotten U, Shah D, Sinner M, Smolnik R, Steinbeck G, Steven D, Svennberg E, Thomas D, True Hills M, van Gelder I, Vardar B, Palà E, Wakili R, Wegscheider K, Wieloch M, Willems S, Witt H, Ziegler A, Daniel Zink M, Kirchhof P
EUROPACE. 2023;25(1):6-27.

Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium
Winters J, Isaacs A, Zeemering S, Kawczynski M, Maesen B, Maessen J, Bidar E, Boukens B, Hermans B, van Hunnik A, Casadei B, Fabritz L, Chua W, Sommerfeld L, Guasch E, Mont L, Batlle M, Hatem S, Kirchhof P, Wakili R, Sinner M, Stoll M, Goette A, Verheule S, Schotten U
J AM HEART ASSOC. 2023;12(22):e031220.

2022

Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death
Brady P, Chua W, Nehaj F, Connolly D, Khashaba A, Purmah Y, Ul-Qamar M, Thomas M, Varma C, Schnabel R, Zeller T, Fabritz L, Kirchhof P
J AM HEART ASSOC. 2022;11(4):.

Smartphone and wearable detected atrial arrhythmias in Older Adults: Results of a fully digital European Case finding study
Fabritz L, Connolly D, Czarnecki E, Dudek D, Guasch E, Haase D, Huebner T, Zlahoda-Huzior A, Jolly K, Kirchhof P, Obergassel J, Schotten U, Vettorazzi E, Winkelmann S, Zapf A, Schnabel R
European heart journal. Digital health. 2022;3(4):610-625.

Remote Design of a Smartphone and Wearable Detected Atrial Arrhythmia in Older Adults Case Finding Study: Smart in OAC - AFNET 9
Fabritz L, Connolly D, Czarnecki E, Dudek D, Zlahoda-Huzior A, Guasch E, Haase D, Huebner T, Jolly K, Kirchhof P, Schotten U, Zapf A, Schnabel R
FRONT CARDIOVASC MED. 2022;9:.

Artificial intelligence for early atrial fibrillation detection
Fabritz L, Obergassel J
LANCET. 2022;400(10359):1173-1175.

Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank
Kany S, Cardoso V, Bravo L, Williams J, Schnabel R, Fabritz L, Gkoutos G, Kirchhof P
HEART. 2022;108(23):1873-1880.

LMNA Mutation in a Family with a Strong History of Sudden Cardiac Death
Keil L, Berisha F, Knappe D, Kubisch C, Shoukier M, Kirchhof P, Fabritz L, Hellenbroich Y, Woitschach R, Magnussen C
GENES-BASEL. 2022;13(2):.

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
Kotanidis C, Xie C, Alexander D, Rodrigues J, Burnham K, Mentzer A, O'Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou E, Badi I, Lyasheva M, Shirodaria C, Lumley S, Constantinides B, Sanderson N, Rodger G, Chau K, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson B, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho L, Neubauer S, Newby D, Channon K, Deanfield J, Antoniades C
LANCET DIGIT HEALTH. 2022;4(10):e705-e716.

Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels
O' Brien S, Holmes A, Johnson D, Kabir S, O' Shea C, O' Reilly M, Avezzu A, Reyat J, Hall A, Apicella C, Ellinor P, Niederer S, Tucker N, Fabritz L, Kirchhof P, Pavlovic D
J MOL CELL CARDIOL. 2022;166:23-35.

High resolution optical mapping of cardiac electrophysiology in pre-clinical models
O'Shea C, Winter J, Kabir S, O'Reilly M, Wells S, Baines O, Sommerfeld L, Correia J, Lei M, Kirchhof P, Holmes A, Fabritz L, Rajpoot K, Pavlovic D
SCI DATA. 2022;9(1):.

Trends in the pharmacological management of atrial fibrillation in UK general practice 2008-2018
Phillips K, Subramanian A, Thomas G, Khan N, Chandan J, Brady P, Marshall T, Nirantharakumar K, Fabritz L, Adderley N
HEART. 2022;108(7):517-522.

Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals
Ripplinger C, Glukhov A, Kay M, Boukens B, Chiamvimonvat N, Delisle B, Fabritz L, Hund T, Knollmann B, Li N, Murray K, Poelzing S, Quinn T, Remme C, Rentschler S, Rose R, Posnack N
AM J PHYSIOL-HEART C. 2022;323(6):H1137-H1166.

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
van der Velden J, Asselbergs F, Bakkers J, Batkai S, Bertrand L, Bezzina C, Bot I, Brundel B, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson S, Dendorfer A, Duncker D, Eschenhagen T, Fabritz L, Falcão-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepeköylü C, Gyongyosi M, Guzik T, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra A, Hulot J, Kuster D, van Laake L, Lecour S, Leiner T, Linke W, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme C, Rosenhahn B, Schotten U, Schulz R, Sipido K, Sluijter J, van Steenbeek F, Steffens S, Terracciano C, Tocchetti C, Vlasman P, Yeung K, Zacchigna S, Zwaagman D, Thum T
CARDIOVASC RES. 2022;118(15):3016-3051.

Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction
Zeemering S, Isaacs A, Winters J, Maesen B, Bidar E, Dimopoulou C, Guasch E, Batlle M, Haase D, Hatem S, Kara M, Kääb S, Mont L, Sinner M, Wakili R, Maessen J, Crijns H, Fabritz L, Kirchhof P, Stoll M, Schotten U
HEART RHYTHM. 2022;19(12):2115-2124.

2021

Mobile Apps to Improve Medication Adherence in Cardiovascular Disease: Systematic Review and Meta-analysis
Al-Arkee S, Mason J, Lane D, Fabritz L, Chua W, Haque M, Jalal Z
J MED INTERNET RES. 2021;23(5):.

Resting cardiac sympathetic firing frequencies suppress terminal norepinephrine transporter uptake
Cao L, Marshall J, Fabritz L, Brain K
AUTON NEUROSCI-BASIC. 2021;232:.

Heart failure in patients with atrial fibrillation: why it matters now more than ever
Chua W, Fabritz L
HEART. 2021;107(16):1278-1279.

Quantification of fibroblast growth factor 23 and N-terminal pro-B-type natriuretic peptide to identify patients with atrial fibrillation using a high-throughput platform: A validation study
Chua W, Law J, Cardoso V, Purmah Y, Neculau G, Jawad-Ul-Qamar M, Russell K, Turner A, Tull S, Nehaj F, Brady P, Kastner P, Ziegler A, Gkoutos G, Pavlovic D, Ferro C, Kirchhof P, Fabritz L
PLOS MED. 2021;18(2):.

Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference
Fabritz L, Crijns H, Guasch E, Goette A, Häusler K, Kotecha D, Lewalter T, Meyer C, Potpara T, Rienstra M, Schnabel R, Willems S, Breithardt G, Camm A, Chan A, Chua W, de Melis M, Dimopoulou C, Dobrev D, Easter C, Eckardt L, Haase D, Hatem S, Healey J, Heijman J, Hohnloser S, Huebner T, Ilyas B, Isaacs A, Kutschka I, Leclercq C, Lip G, Marinelli E, Merino J, Mont L, Nabauer M, Oldgren J, Pürerfellner H, Ravens U, Savelieva I, Sinner M, Sitch A, Smolnik R, Steffel J, Stein K, Stoll M, Svennberg E, Thomas D, Van Gelder I, Vardar B, Wakili R, Wieloch M, Zeemering S, Ziegler P, Heidbuchel H, Hindricks G, Schotten U, Kirchhof P
EUROPACE. 2021;23(3):329-344.

Taking the heavy load off arrhythmogenic right ventricular cardiomyopathy
Fabritz L, Patten M, Kirchhof P
HEART RHYTHM. 2021;18(7):1192-1193.

Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone
Holmes A, Saxena P, Kabir S, O'Shea C, Kuhlmann S, Gupta S, Fobian D, Apicella C, O'Reilly M, Syeda F, Reyat J, Smith G, Workman A, Pavlovic D, Fabritz L, Kirchhof P
HEART RHYTHM. 2021;18(7):1212-1220.

Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation
Künzel S, Hoffmann M, Weber S, Künzel K, Kämmerer S, Günscht M, Klapproth E, Rausch J, Sadek M, Kolanowski T, Meyer-Roxlau S, Piorkowski C, Tugtekin S, Rose-John S, Yin X, Mayr M, Kuhlmann J, Wimberger P, Grützmann K, Herzog N, Küpper J, O'Reilly M, Kabir S, Sommerfeld L, Guan K, Wielockx B, Fabritz L, Nattel S, Ravens U, Dobrev D, Wagner M, El-Armouche A
CIRC RES. 2021;129(8):804-820.

Effects of genetic background, sex, and age on murine atrial electrophysiology
Obergassel J, O'Reilly M, Sommerfeld L, Kabir S, O'Shea C, Syeda F, Eckardt L, Kirchhof P, Fabritz L
EUROPACE. 2021;23(6):958-969.

ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research
Odening K, Gomez A, Dobrev D, Fabritz L, Heinzel F, Mangoni M, Molina C, Sacconi L, Smith G, Stengl M, Thomas D, Zaza A, Remme C, Heijman J
EUROPACE. 2021;23(11):1795-1814.

Coronary microvascular dysfunction is associated with degree of anaemia in end-stage renal disease
Radhakrishnan A, Pickup L, Price A, Law J, McGee K, Fabritz L, Senior R, Steeds R, Ferro C, Townend J
BMC CARDIOVASC DISOR. 2021;21(1):.

Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control
Rathjens F, Blenkle A, Iyer L, Renger A, Syeda F, Noack C, Jungmann A, Dewenter M, Toischer K, El-Armouche A, Müller O, Fabritz L, Zimmermann W, Zelarayan L, Zafeiriou M
CARDIOVASC RES. 2021;117(8):1908-1922.

Mobile health for walking on the tightrope of optimal physical activity to reduce the risk of atrial fibrillation
Schnabel R, Fabritz L, Kirchhof P
EUR HEART J. 2021;42(25):2484-2486.

Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release
Simon J, Vrellaku B, Monterisi S, Chu S, Rawlings N, Lomas O, Marchal G, Waithe D, Syeda F, Gajendragadkar P, Jayaram R, Sayeed R, Channon K, Fabritz L, Swietach P, Zaccolo M, Eaton P, Casadei B
CIRCULATION. 2021;143(5):449-465.

Study design and rationale of the pAtients pResenTing with cOngenital heaRt dIseAse Register (ARTORIA-R)
Sinning C, Zengin E, Diller G, Onorati F, Castel M, Petit T, Chen Y, Lo Rito M, Chiarello C, Guillemain R, Coniat K, Magnussen C, Knappe D, Becher P, Schrage B, Smits J, Metzner A, Knosalla C, Schoenrath F, Miera O, Cho M, Weimann J, Goßling A, Terzi A, Amodeo A, Alfieri S, Angeli E, Ragni L, Napoleone C, Gerosa G, Pradegan N, Rodrigus I, Dumfarth J, de Pauw M, François K, Van Caenegem O, Ancion A, Van Cleemput J, Miličić D, Moza A, Schenker P, Thul J, Steinmetz M, Warnecke G, Ius F, Freyt S, Avsar M, Sandhaus T, Haneya A, Eifert S, Saeed D, Borger M, Welp H, Ablonczy L, Schmack B, Ruhparwar A, Naito S, Hua X, Fluschnik N, Nies M, Keil L, Senftinger J, Ismaili D, Kany S, Csengeri D, Cardillo M, Oliveti A, Faggian G, Dorent R, Jasseron C, Blanco A, Márquez J, López-Vilella R, García-Álvarez A, López M, Rocafort A, Fernández Ó, Prieto-Arevalo R, Zatarain-Nicolás E, Blanchart K, Boignard A, Battistella P, Guendouz S, Houyel L, Para M, Flecher E, Gay A, Épailly É, Dambrin C, Lam K, Ka-Lai C, Cho Y, Choi J, Kim J, Coats L, Crossland D, Mumford L, Hakmi S, Sivathasan C, Fabritz L, Schubert S, Gummert J, Hübler M, Jacksch P, Zuckermann A, Laufer G, Baumgartner H, Giamberti A, Reichenspurner H, Kirchhof P
ESC HEART FAIL. 2021;8(6):5542-5550.

Medical Therapy in Arrhythmogenic Right Ventricular Cardiomyopathy
Sommerfeld L, Aljehani A, Kalla M, Fabritz L
2021. Current Concepts in Arrhythmogenic Cardiomyopathy, Second Edition. Brunckhorst C, Duru F, Saguner A (eds.). 2. ed. Minneapolis, United States: Cardiotext Publishing, 127-134.

2020

Detection of unknown atrial fibrillation by prolonged ECG monitoring in an all-comer patient cohort and association with clinical and Holter variables
Jawad-Ul-Qamar M, Chua W, Purmah Y, Nawaz M, Varma C, Davis R, Maher A, Fabritz L, Kirchhof P
OPEN HEART. 2020;7(1):.

Sex differences in catheter ablation of atrial fibrillation: results from AXAFA-AFNET 5
Kloosterman M, Chua W, Fabritz L, Al-Khalidi H, Schotten U, Nielsen J, Piccini J, Di Biase L, Häusler K, Todd D, Mont L, Van Gelder I, Kirchhof P
EUROPACE. 2020;22(7):1026-1035.

Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity
O'Shea C, Winter J, Holmes A, Johnson D, Correia J, Kirchhof P, Fabritz L, Rajpoot K, Pavlovic D
PROG BIOPHYS MOL BIO. 2020;157:84-93.

Biomarkers Associated With Aortic Valve Calcification: Should We Focus on Sex Specific Processes?
Peeters F, Dudink E, Weijs B, Fabritz L, Chua W, Kietselaer B, Wildberger J, Meex S, Kirchhof P, Crijns H, Schurgers L
FRONT CELL DEV BIOL. 2020;8:.

Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation
Reyat J, Chua W, Cardoso V, Witten A, Kastner P, Kabir S, Sinner M, Wesselink R, Holmes A, Pavlovic D, Stoll M, Kääb S, Gkoutos G, de Groot J, Kirchhof P, Fabritz L
JCI INSIGHT. 2020;5(16):.

Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation
van Ouwerkerk A, Hall A, Kadow Z, Lazarevic S, Reyat J, Tucker N, Nadadur R, Bosada F, Bianchi V, Ellinor P, Fabritz L, Martin J, de Laat W, Kirchhof P, Moskowitz I, Christoffels V
CIRC RES. 2020;127(1):34-50.

JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling
Winters J, von Braunmuhl M, Zeemering S, Gilbers M, Brink T, Scaf B, Guasch E, Mont L, Batlle M, Sinner M, Hatem S, Mansour M, Fabritz L, Sommerfeld L, Kirchhof P, Isaacs A, Stoll M, Schotten U, Verheule S
SCI REP-UK. 2020;10(1):.

Letzte Aktualisierung aus dem FIS: 21.12.2024 - 03:45 Uhr