2024

The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration
Sachs W, Blume L, Loreth D, Schebsdat L, Hatje F, Koehler S, Wedekind U, Sachs M, Zieliniski S, Brand J, Conze C, Florea B, Heppner F, Krüger E, Rinschen M, Kretz O, Thünauer R, Meyer-Schwesinger C
NAT COMMUN. 2024;15(1):1897.

2023

Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer S, Haas F, Wong M, Dumoulin B, Rischke P, Mühlig A, Sachs W, von Cossel K, Schulz K, Muschol N, Gersting S, Muntau A, Kretz O, Hahn O, Rinschen M, Mauer M, Bork T, Grahammer F, Liang W, Eierhoff T, Römer W, Hansen A, Meyer-Schwesinger C, Iaccarino G, Tøndel C, Marti H, Najafian B, Puelles V, Schell C, Huber T
J CLIN INVEST. 2023;133(11):.

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis
Reichelt J, Sachs W, Frömbling S, Fehlert J, Studencka-Turski M, Betz A, Loreth D, Blume L, Witt S, Pohl S, Brand J, Czesla M, Knop J, Florea B, Zielinski S, Sachs M, Hoxha E, Hermans-Borgmeyer I, Zahner G, Wiech T, Krüger E, Meyer-Schwesinger C
NAT COMMUN. 2023;14(1):2114.

2022

The Calcium-Sensing Receptor Stabilizes Podocyte Function in Proteinuric Humans and Mice
Mühlig A, Steingröver J, Heidelbach H, Wingerath M, Sachs W, Hermans-Borgmeyer I, Meyer-Schwesinger C, Choi H, Lim B, Patry C, Hoffmann G, Endlich N, Bracke K, Weiß M, Guse A, Lassé M, Rinschen M, Braun F, Huber T, Puelles V, Schmitt C, Oh J
KIDNEY INT. 2022;101(6):1186-1199.

2021

Tripartite Separation of Glomerular Cell-Types and Proteomes From Reporter-Free Mice
Hatje F, Wedekind U, Sachs W, Loreth D, Reichelt J, Demir F, Kosub C, Heintz L, Tomas N, Huber T, Skuza S, Sachs M, Zielinski S, Rinschen M, Meyer-Schwesinger C
J AM SOC NEPHROL. 2021;32(9):2175-2193.

ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage
Sachs M, Wetzel S, Reichelt J, Sachs W, Schebsdat L, Zielinski S, Seipold L, Heintz L, Müller S, Kretz O, Lindenmeyer M, Wiech T, Huber T, Lüllmann-Rauch R, Lichtenthaler S, Saftig P, Meyer-Schwesinger C
J AM SOC NEPHROL. 2021;32(6):1389-1408.

2020

Distinct modes of balancing glomerular cell proteostasis in mucolipidosis type II and III prevent proteinuria
Sachs W, Sachs M, Krüger E, Zielinski S, Kretz O, Huber T, Baranowsky A, Westermann L, Voltolini Velho R, Floriano Ludwig N, Yorgan T, Di Lorenzo G, Kollmann K, Braulke T, Schwartz I, Schinke T, Danyukova T, Pohl S, Meyer-Schwesinger C
J AM SOC NEPHROL. 2020;31(8):1796-1814.

2019

Thrombospondin Type 1 Domain-Containing 7A Localizes to the Slit Diaphragm and Stabilizes Membrane Dynamics of Fully Differentiated Podocytes
Herwig J, Skuza S, Sachs W, Sachs M, Failla A, Rune G, Meyer T, Fester L, Meyer-Schwesinger C
J AM SOC NEPHROL. 2019;30(5):824-839.

Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks
Reinicke A, Laban K, Sachs M, Kraus V, Walden M, Damme M, Sachs W, Reichelt J, Schweizer M, Janiesch P, Duncan K, Saftig P, Rinschen M, Morellini F, Meyer-Schwesinger C
P NATL ACAD SCI USA. 2019;116(16):7963-7972.

Letzte Aktualisierung aus dem FIS: 21.12.2024 - 03:56 Uhr