A Comprehensive Analysis of Tn and STn Antigen Expression in Esophageal Adenocarcinoma
Mercanoglu B, Karstens K, Giannou A, Meiners J, Lücke J, Seeger P, Brackrock V, Güngör C, Izbicki J, Bockhorn M, Hackert T, Melling N, Wolters-Eisfeld G
CANCERS. 2024;16(2):.

CD301 and LSECtin glycan-binding receptors of innate immune cells serve as prognostic markers and potential predictors of immune response in breast cancer subtypes
Wegscheider A, Wojahn I, Gottheil P, Spohn M, Käs J, Rosin O, Ulm B, Nollau P, Wagener C, Niendorf A, Wolters-Eisfeld G
GLYCOBIOLOGY. 2024;34(3):.

Glycan diversity in ovarian cancer: Unraveling the immune interplay and therapeutic prospects
Wolters-Eisfeld G, Oliveira-Ferrer L
SEMIN IMMUNOPATHOL. 2024;46(6):1-20.

Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Genduso S, Freytag V, Schetler D, Kirchner L, Schiecke A, Maar H, Wicklein D, Gebauer F, Bröker K, Stürken C, Milde-Langosch K, Oliveira-Ferrer L, Ricklefs F, Ewald F, Wolters-Eisfeld G, Riecken K, Unrau L, Krause L, Bohnenberger H, Offermann A, Perner S, Sebens S, Lamszus K, Diehl L, Linder S, Jücker M, Schumacher U, Lange T
J HEMATOL ONCOL. 2023;16(1):.

Unmasking metabolic dependencies in pancreatic cancer aberrant polyamine synthesis as a promising new therapeutic target
Wolters-Eisfeld G, Hackert T, Güngör C
SIGNAL TRANSDUCT TAR. 2023;8(1):.

Truncated O-GalNAc glycans impact on fundamental signaling pathways in pancreatic cancer
Hofmann B, Picksak A, Kwiatkowski M, Grupp K, Jücker M, Bachmann K, Mercanoglu B, Izbicki J, Kahlert C, Bockhorn M, Güngör C, Ewald F, Wolters-Eisfeld G
GLYCOBIOLOGY. 2021;2021:.

SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
von Wenserski L, Schultheiß C, Bolz S, Schliffke S, Simnica D, Willscher E, Gerull H, Wolters-Eisfeld G, Riecken K, Fehse B, Altfeld M, Nollau P, Binder M
LEUKEMIA. 2021;35(4):1073-1086.

The cell adhesion molecule L1 interacts with nuclear proteins via its intracellular domain
Girbes Minguez M, Wolters-Eisfeld G, Lutz D, Buck F, Schachner M, Kleene R
FASEB J. 2020;34(8):9869-9883.

Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power
Karstens K, Bellon E, Polonski A, Wolters-Eisfeld G, Melling N, Reeh M, Izbicki J, Tachezy M
ONCOTARGET. 2020;11(13):1131-1140.

Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer
Konczalla L, Perez D, Wenzel N, Wolters-Eisfeld G, Klemp C, Lüddeke J, Wolski A, Landschulze D, Meier C, Buchholz A, Yao D, Hofmann B, Graß J, Spriestersbach S, Grupp K, Schumacher U, Betzel C, Kapis S, Nuguid T, Steinberg P, Püschel K, Sauter G, Bockhorn M, Uzunoglu F, Izbicki J, Güngör C, El Gammal A
INT J CANCER. 2020;146(6):1618-1630.

Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
Starzonek S, Maar H, Labitzky V, Wicklein D, Rossdam C, Buettner F, Wolters-Eisfeld G, Guengoer C, Wagener C, Schumacher U, Lange T
GLYCOBIOLOGY. 2020;30(9):695-709.

Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC)
Hötzel J, Melling N, Müller J, Polonski A, Wolters-Eisfeld G, Izbicki J, Karstens K, Tachezy M
J CANCER RES CLIN. 2019;145(9):2285-2292.

Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Benten D, Behrang Y, Unrau L, Weissmann V, Wolters-Eisfeld G, Burdak-Rothkamm S, Stahl F, Anlauf M, Grabowski P, Möbs M, Dieckhoff J, Sipos B, Fahl M, Eggers C, Perez D, Bockhorn M, Izbicki J, Lohse A, Schrader J
MOL CANCER RES. 2018;16(3):496-507.

FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas
Grupp K, Uzunoglu F, Melling N, Hofmann B, El Gammal A, Grotelüschen R, Heumann A, Bellon E, Reeh M, Wolters-Eisfeld G, Ghabdan T, Nentwich M, Bachmann K, Bockhorn M, Bogoevski D, Izbicki J, Kutup A
SCI REP-UK. 2018;8(1):17370.

EXPRESSION OF TN ANTIGEN PROMOTES PANCREATIC CARCINOGENESIS IN A TRANSGENIC MOUSE MODEL
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2018.

Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice
Wolters-Eisfeld G, Mercanoglu B, Hofmann B, Wolpers T, Schnabel C, Harder S, Steffen P, Bachmann K, Steglich B, Schrader J, Gagliani N, Schlüter H, Güngör C, Izbicki J, Wagener C, Bockhorn M
EXP MOL MED. 2018;50(10):1-13.

HRG/HER2/HER3 signaling promotes AhR-mediated Memo-1 expression and migration in colorectal cancer
Bogoevska V, Wolters-Eisfeld G, Hofmann B, El Gammal A, Mercanoglu B, Gebauer F, Vashist Y, Bogoevski D, Perez D, Gagliani N, Izbicki J, Bockhorn M, Güngör C
ONCOGENE. 2017;36(17):2394-2404.

TRYPTOPHAN DEGRADATION AS AN ALTERNATIVE ENERGY SOURCE IN PANCREATIC CANCER
Güngör C, Mercanoglu B, Wolters-Eisfeld G, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2017;5: Supplement 1.

Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development
Lutz D, Sharaf A, Drexler D, Kataria H, Wolters-Eisfeld G, Brunne B, Kleene R, Loers G, Frotscher M, Schachner M
SCI REP-UK. 2017;7(1):15268.

Hypoxie induzierte und HIF1A vermittelte differentielle O-Glykosylierung reguliert onkogene Signalwege im duktalen Adenokarzinom des Pankreas
Mercanoglu B, Güngör C, Bockhorn M, Wolters-Eisfeld G
Z GASTROENTEROL. 2017;55(08):KV 222.

HYPOXIA INDUCED HIF1A-MEDIATED DIFFERENTIAL O-GALNAC GLYCOSYLATION DIRECTLY REGULATES SIGNALING PATHWAYS IN PANCREATIC CANCER
Mercanoglu B, Hofmann B, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
UNITED EUR GASTROENT. 2017.

Expression of Tn Antigen Causes Chronic Pancreatitis in a Transgenic Mouse Model
Mercanoglu B, Karstens K, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
EUR SURG RES. 2017.

EXPRESSION OF TN ANTIGEN CAUSES CHRONIC PANCREATITIS IN A TRANSGENIC MOUSE MODEL
Mercanoglu B, Karstens K, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
UNITED EUR GASTROENT. 2017.

Die Expression des Tn Antigens begünstigt die pankreatische Karzinogenese in einem transgenen Mausmodell
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
Z GASTROENTEROL. 2017.

DIFFERENTIALLY O-GLYCOSYLATED CARBOXYL ESTER LIPASE CAUSES A MODY8-LIKE PHENOTYPE IN MICE
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2017.

Synergistische Therapiewirkung der Kombination des Hsp90 Inhibitor AUY922 und des PI3K Inhibitors BYL719 mit Everolimus bei neuroendokrinen Tumoren
Weißmann V, Benten D, Wolters-Eisfeld G, Perez D, Izbicki J, Lohse A, Schrader J
Z GASTROENTEROL. 2017;55(08):KV 402.

Hypoxia induced HIF1a-mediated O-GalNAc glycosylation of cytosolic O-GlcNAcylated proteins to regulate signaling pathways in pancreatic cancer.
Wolters-Eisfeld G, Mercanoglu B, Güngör C, Izbicki J, Bockhorn M
J CLIN ONCOL. 2017;35(15_suppl):e15739-e15739.

Lectin Histochemistry for Metastasizing and Non-metastasizing Cancer Cells
Wolters-Eisfeld G, Schumacher U
Methods Mol Biol. 2017;1560:121-132.

Tenascin-C serum levels and its prognostic power in non-small cell lung cancer
Gebauer F, Gelis S, Zander H, Meyer K, Wolters-Eisfeld G, Izbicki J, Bockhorn M, Tachezy M
ONCOTARGET. 2016;7(15):20945-52.

Aberrant O-GalNAc glycosylation to enhance AKT/mTOR signaling in pancreatic cancer.
Hofmann B, Kwiatkowski M, Izbicki J, Bockhorn M, Güngör C, Ewald F, Wolters-Eisfeld G
J CLIN ONCOL. 2016;34(15_suppl):e15673-e15673.

Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic Syndrome: a case-control study
Doulgere J, Otto B, Nassour M, Wolters-Eisfeld G, Rohde H, Magnus T, Wagener C, Streichert T
BMJ OPEN. 2015;5(3):e005659.

COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer
Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak A, Harder S, El Gammal A, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki J, Jücker M, Bockhorn M, Wolters-Eisfeld G
MOL CANCER. 2015;14(1):109.

Cellular Uptake Behavior of Glycoconjugated and Micellar-Encapsulated Quantum Dots on HeLa Cervical Cancer Cells
Merkl J, Schmidtke C, Safi M, Muroski M, Alpers D, Tran H, Ostermann J, Gärtner S, Strouse G, Wolters-Eisfeld G, Mattoussi H, Weller H
2015. Biotech, Biomaterials and Biomedical: TechConnect Briefs 2015. CRC Press, 78-81.

The role of RANK-signaling in tumor cell proliferation and migration in pancreatic adenocarcinoma.
El Gammal A, Sander N, Aljonna F, Friedenberger H, Leonie K, Güngör C, Wolters-Eisfeld G, Hofmann B, Bockhorn M, Izbicki J, Perez D
2014. J Clin Oncol. suppl; abstr e15193.

Pancreatic cancer
Güngör C, Hofmann B, Wolters-Eisfeld G, Bockhorn M
BRIT J PHARMACOL. 2014;171(4):849-858.

ABO blood group IgM isoagglutinins interact with tumor-associated O-glycan structures in pancreatic cancer
Hofmann B, Stehr A, Dohrmann T, Güngör C, Herich L, Hiller J, Harder S, Ewald F, Gebauer F, Tachezy M, Precht C, Izbicki J, Bockhorn M, Wagener C, Wolters-Eisfeld G
CLIN CANCER RES. 2014;20(23):6117-26.

Cathepsin E generates a sumoylated intracellular fragment of the cell adhesion molecule L1 to promote neuronal and Schwann cell migration as well as myelination
Lutz D, Wolters-Eisfeld G, Schachner M, Kleene R
J NEUROCHEM. 2014;128(5):713-24.

The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer
Rawnaq T, Dietrich L, Wolters-Eisfeld G, Uzunoglu F, Vashist Y, Bachmann K, Simon R, Izbicki J, Bockhorn M, Güngör C
MOL CANCER RES. 2014;12(5):670-80.

Activated Leukocyte Cell Adhesion Molecule (CD166): An "Inert" Cancer Stem Cell Marker for Non-Small Cell Lung Cancer?
Tachezy M, Zander H, Wolters-Eisfeld G, Müller J, Wicklein D, Gebauer F, Izbicki J, Bockhorn M
STEM CELLS. 2014;32(6):1429-1436.

Protein domain histochemistry (PDH): binding of the carbohydrate recognition domain (CRD) of recombinant human glycoreceptor CLEC10A (CD301) to formalin-fixed, paraffin-embedded breast cancer tissues.
Nollau P, Wolters-Eisfeld G, Seyed Mortezai N, Kurze A, Klampe B, Debus A, Bockhorn M, Niendorf A, Wagener C
J HISTOCHEM CYTOCHEM. 2013;61(3):199-205.

Generation and nuclear translocation of sumoylated transmembrane fragment of cell adhesion molecule L1.
Lutz D, Wolters G, Joshi G, Djogo N, Jakovcevski I, Schachner M, Kleene R
J BIOL CHEM. 2012;287(21):17161-17175.

Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients.
Zander H, Rawnaq T, von Wedemeyer M, Tachezy M, Kunkel M, Wolters G, Bockhorn M, Schachner M, Izbicki J, Kaifi J
BMC CANCER. 2011;11:1-7.

The 14-3-3 protein binds to the cell adhesion molecule L1, promotes L1 phosphorylation by CKII and influences L1-dependent neurite outgrowth.
Ramser E, Wolters G, Dityateva G, Dityatev A, Schachner M, Tilling T
PLOS ONE. 2010;5(10):13462.

Letzte Aktualisierung aus dem FIS: 21.11.2024 - 03:52 Uhr