Welcome to the Institute of Clinical Chemistry and Laboratory Medicine

Routine diagnostic procedures

In the Institute of Clinical Chemistry and Laboratory Medicine at the University Medical Center Hamburg-Eppendorf lab tests are carried out for every institute and department of the UKE. Many diagnostic parameters are determined by the analysis of body fluids such as blood or urine. Our lab guide provides detailed information on the test materials, the pre-analytical phase and the diagnostic approach. As an academic institution the focus is not solely on biomedical research and clinical studies. Teaching students of medicine, dentistry and the natural sciences is also an important responsibility.

Research

The study of the relationship between inflammation and blood coagulation is one of the major research areas addressed by the institute. Research is focused on molecular mechanisms, diagnostics and therapeutic concepts for Factor XII attributable disorders in the contact phase of blood coagulation and neutrophil extracellular networks (NETs). The analytical core of the research is the development of systems biological proteomic analysis. Other activities include collaboration and the support of projects with veterinary medical analysis and mass spectrometry and in special research areas, or CRC projects (Collaborative Research Centres) such as CRC 841, CRC 1192, KlFo 306, CRC 877 and others supported by the European Research Council (ERC).

Curriculum & professional development

The Institute of Clinical Chemistry plays a teaching role in the training and academic education of medical students. Details of the current lecture program, training, work experience opportunities and courses can be found on the german pages.

Diagnostics

The Institute of Clinical Chemistry and Laboratory Medicine conducts laboratory medicinal analyses for all UKE-based medicinal departments as well as for external clients. We determine multiple diagnostic parameters from different matrices such as blood, urine or liquor. By this around 3500 samples are analysed on daily basis, generating an average of 18.000 single parameter readings. The doctors interpret the results supported by a powerfull laboratory IT-system.

Research

The Institute hosts six independent research groups which cover topics from the fields of inflammation and hemostasiology. The research is focused on the factor XII-contactphase system with polyphosphates and neutrophil extracellular traps (NETs). By investigating the molecular mechanisms underlying these processes new therapeutic treatments as well as advanced diagnostic procedures are developed. We support cooperative projects through veterinary medical analytics and mass spectrometry-based proteomics. Our work is founded by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) within the colaborative research centers SFB 841, SFB 1192, KlFo 306 and SFB 877 as well as by the European Union through two Marie Skłodowska-Curie Grants and one European Research Council (ERC) Grant.