Role of the NO-GC/cGMP signaling pathway in platelet biomechanics
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The History of Extracorporeal Membrane Oxygenation and the Development of Extracorporeal Membrane Oxygenation Anticoagulation
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Proximity labeling of host factor ANXA3 in HCV infection reveals a novel LARP1 function in viral entry
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The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
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Targeting factor XIIa for therapeutic interference with hereditary angioedema
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Integrated proteomics spotlight the proteasome as a therapeutic vulnerability in Embryonal Tumors with Multilayered Rosettes
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Proteomic analysis of the urothelial cancer landscape
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Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease
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Nanosecond infrared laser (NIRL) for cutting roots of human teeth: thermal effects and quality of cutting edges
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Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level
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Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo
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Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
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Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick
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The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation
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Highly sensitive therapeutic drug monitoring of infliximab in serum by targeted mass spectrometry in comparison to ELISA data
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Application of sample displacement batch chromatography for fractionation of proteoforms
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Novel Catechol O-methyltransferases from Lentinula edodes Catalyze the Generation of Taste-Active Flavonoids
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Extreme founder effect associated with hyperglycemia and hyperlipidemia on the island of NIAS/Indonesia
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Different Forms of TFF3 in the Human Endocervix, including a Complex with IgG Fc Binding Protein (FCGBP), and Further Aspects of the Cervico-Vaginal Innate Immune Barrier
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Thromboinflammatorische Mechanismen bei kardiovaskulären Erkrankungen
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STAR PROTOC. 2024;5(1):102793.

Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy
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Personalised blood pressure management during major noncardiac surgery and postoperative neurocognitive disorders: a randomised trial
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The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System
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Glycolytic reprogramming fuels myeloid cell-driven hypercoagulability
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16S rRNA sequencing analysis of the oral and fecal microbiota in colorectal cancer positives versus colorectal cancer negatives in Iranian population
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Correction to: 16 S rRNA sequencing analysis of the oral and fecal microbiota in colorectal cancer positives versus colorectal cancer negatives in Iranian population
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Development of new peptidomimetic NADPH oxidase inhibitors with antithrombotic properties
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Evidence-based cutoffs for total and adjusted calcium: a major factor in detecting severe hypo- and hypercalcemia
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HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
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An Update on Polyphosphate In Vivo Activities
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Anaplastic histology and distinct molecular features in a small series of spinal cord ependymomas
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Antiplatelet drugs do not protect from platelet-leukocyte aggregation in coronary artery disease
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Assay for Characterizing Adsorption-Properties of Surfaces (APS)
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Top-down proteomics and proteoforms - special issue
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PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates
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Sphingosine-1-phosphate receptor 3 regulates the transendothelial transport of high-density lipoproteins and low-density lipoproteins in opposite ways
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Effect of periprocedural furosemide-induced diuresis with matched isotonic intravenous hydration in patients with chronic kidney disease undergoing transcatheter aortic valve implantation
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Leukotriene B4: A potential mediator and biomarker for cardiac allograft vasculopathy
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Extracellular proteins enhance Cupriavidus pauculus nickel tolerance and cell aggregate formation
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Optimizing thiopurine therapy in autoimmune hepatitis: A multi-center study on monitoring metabolite profiles and co-therapy with allopurinol
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The undetected murder?: Evaluation and validation of a practicable and rapid inductively coupled plasma-mass spectrometry method for the detection of arsenic, lead, and thallium intoxications in postmortem blood
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DRUG TEST ANAL. 2024 [Epub ahead of print].

Quantification of midostaurin in plasma and serum by stable isotope dilution liquid chromatography-tandem mass spectrometry: Application to a cohort of patients with acute myeloid leukemia
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EUR J HAEMATOL. 2024;112(6):879-888.

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
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A single-domain antibody targeting factor XII inhibits both thrombosis and inflammation
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IL-22 promotes liver regeneration after portal vein ligation
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Fat tissue quantity, waist circumference or waist-to-hip ratio in patients with chronic kidney disease: A systematic review and meta-analysis
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Detection and Isolation of Circulating Tumor Cells from Breast Cancer Patients Using CUB Domain-Containing Protein 1
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Cardiovascular Functions of Ena/VASP Proteins: Past, Present and Beyond
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Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models
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SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model
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Targeting NETs using dual-active DNase1 variants
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Iron Chelation with Deferasirox Suppresses the Appearance of Labile Plasma Iron During Conditioning Chemotherapy Prior to Allogeneic Stem Cell Transplantation
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Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2
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Glycated albumin modulates the contact system with implications for the kallikrein-kinin and intrinsic coagulation systems
Hardy L, Bohinc D, Bane K, Heal S, Hethershaw E, Ali M, Palmer-Dench T, Foster R, Longstaff C, Renné T, Stavrou E, Philippou H
J THROMB HAEMOST. 2023;21(4):814-827.

Seroprevalence of arthropod-borne bacterial infections in homeless individuals in Hamburg in 2020
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INFECTION. 2023;51(6):1819-1822.

The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3
Höpfner D, Cichy A, Pogenberg V, Krisp C, Mezouar S, Bach N, Grotheer J, Zarza S, Martinez E, Bonazzi M, Feige M, Sieber S, Schlüter H, Itzen A
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In-vivo functions and regulation of polyphosphate in the vascular system
Huang W, Mailer R, Renné T
CURR OPIN HEMATOL. 2023;30(5):159-166.

Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
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NAT COMMUN. 2023;14(1):3280.

Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
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NAT COMMUN. 2023;14(1):7752.

EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma
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SCI REP-UK. 2023;13(1):20827.

Erfahrungsbericht: Sandra Konrath am Royal College of Surgeons in Ireland (RCSI) in Dublin
Konrath S
HAMOSTASEOLOGIE. 2023;43(4):300-300.

Regulation of coagulation activation in newly diagnosed AML by the heme enzyme myeloperoxidase
Langer F, Quick H, Beitzen-Heineke A, Janjetovic S, Mäder J, Lehr C, Bokemeyer C, Kuta P, Renné T, Fiedler W, Beckmann L, Klingler F, Rolling C
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An integrated organoid omics map extends modeling potential of kidney disease
Lassé M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, Kylies D, Hutzfeldt A, Bonin L, Dumoulin B, Menon R, Vega-Warner V, Eichinger F, Alakwaa F, Fermin D, Billing A, Minakawa A, McCown P, Rose M, Godfrey B, Meister E, Wiech T, Noriega M, Chrysopoulou M, Brandts P, Ju W, Reinhard L, Hoxha E, Grahammer F, Lindenmeyer M, Huber T, Schlüter H, Thiel S, Mariani L, Puelles V, Braun F, Kretzler M, Demir F, Harder J, Rinschen M
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Repetitive Antigen Responses of LDL-Reactive CD4+ T Cells Induce Tr1 Cell-Mediated Immune Tolerance
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Cutaneous manifestations in Costello syndrome: HRAS p.Gly12Ser affects RIN1-mediated integrin trafficking in immortalized epidermal keratinocytes
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HUM MOL GENET. 2023;32(2):304-318.

Direct 3D Sampling of the Embryonic Mouse Head: Layer-wise Nanosecond Infrared Laser (NIRL) Ablation from Scalp to Cortex for Spatially Resolved Proteomics
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Polyphosphate-loaded silk fibroin membrane as hemostatic agent in oral surgery: a pilot study
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Pathogenicity of Human anti-PLA2R1 Antibodies in Minipigs: A Pilot Study
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A comprehensive network map of IL-17A signaling pathway
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J CELL COMMUN SIGNAL. 2023;17(1):209-215.

Absence of Malaria-Associated Coagulopathy in Asymptomatic Plasmodium falciparum Infection: Results From a Cross-sectional Study in the Ashanti Region, Ghana
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Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals
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PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2
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Kidney outcome after mild to moderate COVID-19
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Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function
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Multi-omics approaches to study platelet mechanisms
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Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease
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Lipidome Analysis of Oropharyngeal Tumor Tissues Using Nanosecond Infrared Laser (NIRL) Tissue Sampling and Subsequent Mass Spectrometry
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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
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Prognostic utility of a multi-biomarker panel in patients with suspected myocardial infarction
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Immature human engineered heart tissues engraft in a guinea pig chronic injury model
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Association between periodontitis and depression severity - A cross-sectional study of the older population in Hamburg
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Human platelets release amyloid peptides β1-40 and β1-42 in response to haemostatic, immune, and hypoxic stimuli
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RES PRACT THROMB HAE. 2023;7(4):.

The Forms of the Lectin Tff2 Differ in the Murine Stomach and Pancreas: Indications for Different Molecular Functions
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Differential gene expression of BCL-2, ZEB2-AS1 and BALR-2 in prostate cancer and benign prostatic hyperplasia
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Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
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Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy
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Circulating Cellular Communication Network Factor 1 Protein as a Sensitive Liquid Biopsy Marker for Early Detection of Breast Cancer
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Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis
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Evaluation of the AFIAS-1 thyroid-stimulating hormone point of care test and comparison with laboratory-based devices
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CLIN CHEM LAB MED. 2022;60(7):1031-1038.

A Thromboxane A2 Receptor-Driven COX-2-Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis
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Combination of Biochemical and Cytological Findings for Better Diagnosis in Pleural Effusions
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Oral HRAS Mutation in Orofacial Nevus Sebaceous Syndrome (Schimmelpenning-Feuerstein-Mims-Syndrome): A Case Report With a Literature Survey
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Prevalence and risk factors of undiagnosed diabetes mellitus among gastroenterological patients: a HbA1c-based single center experience – Prevalence of undiagnosed diabetes in gastroenterological patients
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Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy
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Correction to An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry
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J PROTEOME RES. 2022;21(10):.

Sealing Behavior of a New Material Combination in Two-Part Dental Implant Systems: An In Vitro Examination
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Lymphatic Mechanoregulation in Development and Disease
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Na,K-ATPase α1 and β-subunits show distinct localizations in the nervous tissue of the large milkweed bug
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CELL TISSUE RES. 2022;388(3):503-519.

Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
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Effect of intraoperative personalized goal-directed hemodynamic management on acute myocardial injury in high-risk patients having major abdominal surgery: a post-hoc secondary analysis of a randomized clinical trial
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J CLIN MONIT COMPUT. 2022;36(6):1775-1783.

Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels
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An Update on Safe Anticoagulation
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HAMOSTASEOLOGIE. 2022;42(1):65-72.

An update on factor XII-driven vascular inflammation
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Commentary on "Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa": Small molecule factor XIa inhibitor asundexian allows for safer anticoagulation
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J THROMB HAEMOST. 2022;20(6):1309-1311.

Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
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Platelet-Derived Procoagulant Microvesicles Are Elevated in Patients with Retinal Vein Occlusion (RVO)
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J CLIN MED. 2022;11(17):.

Disturbed lipid and amino acid metabolisms in COVID-19 patients
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J MOL MED. 2022;100(4):555-568.

Centrosome-dependent microtubule modifications set the conditions for axon formation
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CELL REP. 2022;39(3):110686.

Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
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Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme
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Liver damage promotes pro-inflammatory T-cell responses against apolipoprotein B-100
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Differences in somatostatin receptor subtype expression in patients with acromegaly: new directions for targeted therapy?
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HORM-INT J ENDOCRINO. 2022;21(1):79-89.

Oral Microbiota as Novel Biomarkers for Colorectal Cancer Screening
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Diagnostic potential of extracellular vesicles in meningioma patients
Ricklefs F, Maire C, Wollmann K, Dührsen L, Fita K, Sahm F, Herold-Mende C, von Deimling A, Kolbe K, Holz M, Bergmann L, Fuh M, Schlüter H, Alawi M, Reimer R, Sven P, Glatzel M, Westphal M, Lamszus K
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Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery
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J THROMB HAEMOST. 2022;20(2):353-365.

POLAR – „POLypharmazie, Arzneimittelwechselwirkungen und Risiken“ – wie können Daten aus der stationären Krankenversorgung zur Beurteilung beitragen?
Scherag A, Andrikyan W, Dreischulte T, Dürr P, Fromm M, Gewehr J, Jaehde U, Kesselmeier M, Maas R, Thürmann P, Frank M, Neumann D, Palm J, Peschel T, Räuscher E, Schulze S, Thalheim T, Wendt T, Löffler M
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Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections
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FRONT CELL INFECT MI. 2022;12:.

Thyroid function, thyroid antibodies and early postnatal development in neonates of mothers with thyroid disorders
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The MCP-1 rs1024611 and MTHFR rs1801133 gene variations and expressions in alopecia areata: A pilot study
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IMMUN INFLAMM DIS. 2022;10(2):209-217.

The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner
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REDOX BIOL. 2022;52:102287.

PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
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Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors
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Tissue Sampling and Homogenization with NIRL Enables Spatially Resolved Cell Layer Specific Proteomic Analysis of the Murine Intestine
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HarmonizR enables data harmonization across independent proteomic datasets with appropriate handling of missing values
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A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes
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J THROMB HAEMOST. 2022;20(3):729-741.

Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions
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Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics
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ANAL CHEM. 2022;94(31):10893-10906.

Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi N, Beck S, Jaeckstein M, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G
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Forensic biomarkers of lethal traumatic brain injury
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INT J LEGAL MED. 2022;136(3):871-886.

Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass
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MICROORGANISMS. 2021;9(8):1581.

Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues
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MOL THER-METH CLIN D. 2021;23:418-423.

Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells
Bartkowiak K, Heidrich I, Kwiatkowski M, Gorges T, Andreas A, Geffken M, Verpoort K, Müller V, Schlüter H, Pantel K
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Monocyte activation and acquired autoimmune protein S deficiency promote disseminated intravascular coagulation in a patient with primary antiphospholipid syndrome
Beckmann L, Voigtländer M, Holstein K, Lennartz M, Schneider S, Haddad M, Renné T, Bokemeyer C, Rolling C, Langer F
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Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources
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Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective
Brenna S, Krisp C, Altmeppen H, Magnus T, Puig B
INT J MOL SCI. 2021;22(3):1365.

Effect of five different pneumatic tube carrier inserts on mechanical sample stress: a multicentre evaluation
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CLIN CHEM LAB MED. 2021;59(8):e313-e316.

Tacrolimus impairs Kupffer cell capacity to control bacteremia: why transplant recipients are susceptible to infection
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HEPATOLOGY. 2021;73(5):1967-1984.

Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III
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GENET MED. 2021;23(12):2369-2377.

Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma
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Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation
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Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD
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Complementing the pulp proteome via sampling with a picosecond infrared laser (PIRL)
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CLIN ORAL INVEST. 2021;25(12):6757-6768.

Persistent Endotheliopathy in the Pathogenesis of Long COVID Syndrome
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J THROMB HAEMOST. 2021;19(10):2546-2553.

Mechanoregulation von lymphatischen Endothelzellen
Frye M
Lymphologie in Forschung und Praxis. 2021;2021(2):64-69.

EVL regulates VEGF receptor-2 internalization and signaling in developmental angiogenesis
Frye M, Zink J, Frömel T, Carlantoni C, John D, Schreier D, Weigert A, Laban H, Salinas G, Stingl H, Günther L, Popp R, Hu J, Vanhollebeke B, Schmidt H, Acker-Palmer A, Renné T, Fleming I, Benz P
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Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function
Gaspar R, Ferreira P, Mitchell J, Pula G, Gibbins J
FREE RADICAL BIO MED. 2021;165:395-400.

Protein Disulphide Isomerase and NADPH Oxidase 1 Cooperate to Control Platelet Function and Are Associated with Cardiometabolic Disease Risk Factors
Gaspar R, Sage T, Little G, Kriek N, Pula G, Gibbins J
ANTIOXIDANTS-BASEL. 2021;10(3):.

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Volker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou E, Rangaswamy C, Mailer R, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin T, Renné T
BLOOD. 2021;138(22):2256-2268.

An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry
Guan Y, Zhang M, Gaikwad M, Voss H, Fazel R, Ansari S, Shen H, Wang J, Schlüter H
J PROTEOME RES. 2021;20(7):3654-3663.

Comparative Analysis of Different N-glycan Preparation Approaches and Development of Optimized Solid-Phase Permethylation Using Mass Spectrometry
Guan Y, Zhang M, Wang J, Schlüter H
J PROTEOME RES. 2021;20(5):2914-2922.

Multiplexed complexome profiling using tandem mass tags
Guerrero-Castillo S, Krisp C, Küchler K, Arnold S, Schlüter H, Gersting S
BBA-BIOENERGETICS. 2021;1862(9):.

Crizanlizumab: A CRITICAL Drug During a CRITICAL Time?
Gue Y, Pula G, Lip G
JACC-BASIC TRANSL SC. 2021;6(12):946-947.

Tissue Sampling and Homogenization in the Sub-Microliter Scale with a Nanosecond Infrared Laser (NIRL) for Mass Spectrometric Proteomics
Hahn J, Moritz M, Voß H, Pelczar P, Huber S, Schlüter H
INT J MOL SCI. 2021;22(19):.

Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
Heestermans M, Naudin C, Mailer R, Konrath S, Klaetschke K, Jämsä A, Frye M, Deppermann C, Pula G, Kuta P, Friese M, Gelderblom M, Sickmann A, Preston R, Nofer J, Rose-John S, Butler L, Salomon O, Stavrou E, Renné T
NAT COMMUN. 2021;12(1):5596 - 5613.

Sample Displacement Batch Chromatography of Proteins: 2nd Edition
Heikaus L, Hidayah S, Gaikwad M, Kotasinska M, Richter V, Kwiatkowski M, Schlüter H
Methods Mol Biol. 2021;2178:285-299.

Plasmin-mediated Cleavage of High Molecular Weight Kininogen Contributes to Acetaminophen-Induced Acute Liver Failure
Henderson M, Sparkenbaugh E, Wang S, Ilich A, Noubouossie D, Mailer R, Renné T, Flick M, Luyendyk J, Chen Z, Strickland S, Stravitz R, McCrae K, Key N, Pawlinski R
BLOOD. 2021;138(3):259-272.

Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB
Holliday H, Roden D, Junankar S, Wu S, Baker L, Krisp C, Chan C, McFarland A, Skhinas J, Cox T, Pal B, Huntington N, Ormandy C, Carroll J, Visvader J, Molloy M, Swarbrick A
ISCIENCE. 2021;24(2):.

Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors
Iglesias M, Kruse L, Sanchez-Rivera L, Enge L, Dusart P, Hong M, Uhlén M, Renné T, Schwenk J, Bergstrom G, Odeberg J, Butler L
ARTERIOSCL THROM VAS. 2021;41(12):2990-3004.

Intravital Imaging Allows Organ-Specific Insights Into Immune Functions
Jorch S, Deppermann C
FRONT CELL DEV BIOL. 2021;9:.

Neuroserpin Is Strongly Expressed in the Developing and Adult Mouse Neocortex but Its Absence Does Not Perturb Cortical Lamination and Synaptic Proteome
Kement D, Reumann R, Schostak K, Voß H, Douceau S, Dottermusch M, Schweizer M, Schlüter H, Vivien D, Glatzel M, Galliciotti G
FRONT NEUROANAT. 2021;15:627896.

Mechanism, Functions, and Diagnostic Relevance of FXII Activation by Foreign Surfaces
Konrath S, Mailer R, Renné T
HAMOSTASEOLOGIE. 2021;41(6):489-501.

Investigation of the Proteomes of the Truffles Tuber albidum pico, T. aestivum, T. indicum, T. magnatum, and T. melanosporum
Krösser D, Dreyer B, Siebels B, Voß H, Krisp C, Schlüter H
INT J MOL SCI. 2021;22(23):.

Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration
Law A, Jalal S, Pallett T, Mosis F, Guni A, Brayford S, Yolland L, Marcotti S, Levitt J, Poland S, Rowe-Sampson M, Jandke A, Köchl R, Pula G, Ameer-Beg S, Stramer B, Krause M
NAT COMMUN. 2021;12(1):5687.

Zinc regulates reactive oxygen species generation in platelets
Lopes-Pires M, Ahmed N, Vara D, Gibbins J, Pula G, Pugh N
PLATELETS. 2021;32(3):368-377.

Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage
Mader M, Böger R, Appel D, Schwedhelm E, Haddad M, Mohme M, Lamszus K, Westphal M, Czorlich P, Hannemann J
J CEREBR BLOOD F MET. 2021;41(8):1964-1977.

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate
Mailer R, Allende M, Heestermans M, Schweizer M, Deppermann C, Frye M, Pula G, Odeberg J, Gelderblom M, Rose-John S, Sickmann A, Blankenberg S, Huber T, Kubisch C, Maas C, Gambaryan S, Firsov D, Stavrou E, Butler L, Renné T
BLOOD. 2021;137(10):1392-1405.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Immunothrombosis and thromboinflammation in host defense and disease
Martinod K, Deppermann C
PLATELETS. 2021;32(3):314-324.

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density
Middelkamp M, Ruck L, Krisp C, Sumisławski P, Mohammadi B, Dottermusch M, Meister V, Küster L, Schlüter H, Windhorst S, Neumann J
ACTA NEUROPATHOL COM. 2021;9(1):185.

A Biomarker Model to Distinguish Types of Myocardial Infarction and Injury
Neumann J, Weimann J, Sörensen N, Hartikainen T, Haller P, Lehmacher J, Brocks C, Tenhaeff S, Karakas M, Renné T, Blankenberg S, Zeller T, Westermann D
J AM COLL CARDIOL. 2021;78(8):781-790.

Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR
Olearo F, Nörz D, Heinrich F, Sutter J, Roedl K, Schultze A, Wiesch J, Braun P, Oestereich L, Kreuels B, Wichmann D, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2021;137:.

Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke M, Clausen B, Ludewig P, Vienhues J, Bedke T, Javidi E, Rissiek B, Jank L, Brockmann L, Sandrock I, Degenhardt K, Jander A, Roth V, Schädlich I, Prinz I, Flavell R, Kobayashi Y, Renné T, Gerloff C, Huber S, Magnus T, Gelderblom M
J NEUROINFLAMM. 2021;18(1):.

Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General
Pischke S, Tamanaei S, Mader M, Wiesch J, Petersen-Benz C, Haddad M, Addo M, Schmidt T, Huber T, Krebs C, Steinmetz O, Turner J, Hoxha E, Horvatits T
PATHOGENS. 2021;11(1):.

Polyanions in Coagulation and Thrombosis: Focus on Polyphosphate and NETs
Rangaswamy C, Englert H, Deppermann C, Renné T
THROMB HAEMOSTASIS. 2021;121(8):1021-1030.

The contact system in liver injury
Rangaswamy C, Mailer R, Englert H, Konrath S, Renné T
SEMIN IMMUNOPATHOL. 2021;43(4):507-517.

GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi
Rauch J, Barton J, Kwiatkowski M, Wunderlich M, Steffen P, Moderzynski K, Papp S, Höhn K, Schwanke H, Witt S, Richardt U, Mehlhoop U, Schlüter H, Pianka V, Fleischer B, Tappe D, Osterloh A
PLOS ONE. 2021;16(6):.

MR-proAdrenomedullin as a predictor of renal replacement therapy in a cohort of critically ill patients with COVID-19
Roedl K, Jarczak D, Fischer M, Haddad M, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Karakas M, Kluge S, Nierhaus A
BIOMARKERS. 2021;26(5):417-424.

HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation
Roggenkamp H, Khansahib I, Hernandez C L, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla A, Meier C, Fliegert R, Walseth T, Flügel A, Diercks B, Guse A
SCI SIGNAL. 2021;14(675):.

Lactate metabolism in strictly anaerobic microorganisms with a soluble NAD+ -dependent l-lactate dehydrogenase
Rosenbaum F, Poehlein A, Egelkamp R, Daniel R, Harder S, Schlüter H, Schoelmerich M
ENVIRON MICROBIOL. 2021;23(8):4661-4672.

High estradiol and low testosterone levels are associated with critical illness in male but not in female COVID-19 patients: a retrospective cohort study
Schroeder M, Schaumburg B, Mueller Z, Parplys A, Jarczak D, Roedl K, Nierhaus A, Heer G, Grensemann J, Schneider B, Stoll F, Bai T, Jacobsen H, Zickler M, Stanelle-Bertram S, Klaetschke K, Renné T, Meinhardt A, Aberle J, Hiller J, Peine S, Kreienbrock L, Klingel K, Kluge S, Gabriel G
EMERG MICROBES INFEC. 2021;10(1):1807-1818.

Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice
Schumacher N, Yan K, Gandraß M, Müller M, Krisp C, Häsler R, Carambia A, Nofer J, Bernardes J, Khouja M, Thomsen I, Chalupsky K, Bolik J, Hölscher C, Wunderlich T, Herkel J, Rosenstiel P, Schramm C, Schlüter H, Renné T, Mittrücker H, Rose-John S, Schmidt-Arras D
J HEPATOL. 2021;74(2):407-418.

Identifying Circulating Urotensin II and Urotensin II-Related Peptide-Generating Enzymes in the Human Plasma Fraction Cohn IV-4
Schuster R, Steffen P, Dreyer B, Rohn S, Schlüter H, Riedner M
J PROTEOME RES. 2021;20(12):5368-5378.

Proteomics: A Tool to Study Platelet Function
Shevchuk O, Begonja A, Gambaryan S, Totzeck M, Rassaf T, Huber T, Greinacher A, Renne T, Sickmann A
INT J MOL SCI. 2021;22(9):4776.

Diagnostic Validation of a High-Sensitivity Cardiac Troponin I Assay
Sörensen N, Goßling A, Neumann J, Hartikainen T, Haller P, Scharlemann L, Lehmacher J, Ziegler A, Blankenberg S, Zeller T, Nordholt G, Renné T, Westermann D
CLIN CHEM. 2021;67(9):1230-1239.

Differences in measurement of high-sensitivity troponin in an on-demand and batch-wise setting
Sörensen N, Neumann J, Ojeda F, Renné T, Karakas M, Blankenberg S, Westermann D, Zeller T
EUR HEART J-ACUTE CA. 2021;10(3):302–309.

Vertically transferred maternal immune cells promote neonatal immunity against early life infections
Stelzer I, Urbschat C, Schepanski S, Thiele K, Triviai I, Wieczorek A, Alawi M, Ohnezeit D, Kottlau J, Huang J, Fischer N, Mittrücker H, Solano M, Fehse B, Diemert A, Stahl F, Arck P
NAT COMMUN. 2021;12(1):4706.

Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy
Tallarek A, Urbschat C, Fonseca Brito L, Stanelle-Bertram S, Krasemann S, Frascaroli G, Thiele K, Wieczorek A, Felber N, Lütgehetmann M, Markert U, Hecher K, Brune W, Stahl F, Gabriel G, Diemert A, Arck P
FRONT IMMUNOL. 2021;12:698578.

Diabetes and Thrombosis: A Central Role for Vascular Oxidative Stress
Vaidya A, Wolska N, Vara D, Mailer R, Schröder K, Pula G
ANTIOXIDANTS-BASEL. 2021;10(5):706.

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis
Vara D, Mailer R, Tarafdar A, Wolska N, Heestermans M, Konrath S, Spaeth M, Renné T, Schröder K, Pula G
ARTERIOSCL THROM VAS. 2021;41(2):683-697.

Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein
Velagapudi S, Rohrer L, Poti F, Feuerborn R, Perisa D, Wang D, Panteloglou G, Potapenko A, Yalcinkaya M, Hülsmeier A, Hesse B, Lukasz A, Liu M, Parks J, Christoffersen C, Stoffel M, Simoni M, Nofer J, von Eckardstein A
ARTERIOSCL THROM VAS. 2021;41(10):e468-e479.

Primordial GATA6 macrophages function as extravascular platelets in sterile injury
Zindel J, Peiseler M, Hossain M, Deppermann C, Lee W, Haenni B, Zuber B, Deniset J, Surewaard B, Candinas D, Kubes P
SCIENCE. 2021;371(6533):.

Irisin: Still chasing shadows
Albrecht E, Schering L, Buck F, Vlach K, Schober H, Drevon C, Maak S
MOL METAB. 2020;34:124-135.

Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis
Arnold J, Schattschneider J, Blechner C, Krisp C, Schlüter H, Schweizer M, Nalaskowski M, Oliveira-Ferrer L, Windhorst S
J EXP CLIN CANC RES. 2020;39(1):205.

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer
Baker L, Holliday H, Roden D, Krisp C, Wu S, Junankar S, Serandour A, Mohammed H, Nair R, Sankaranarayanan G, Law A, McFarland A, Simpson P, Lakhani S, Dodson E, Selinger C, Anderson L, Samimi G, Hacker N, Lim E, Ormandy C, Naylor M, Simpson K, Nikolic I, O'Toole S, Kaplan W, Cowley M, Carroll J, Molloy M, Swarbrick A
BREAST CANCER RES. 2020;22(1):63.

Diagnostic strategy for females suspected of Fabry disease
Balendran S, Oliva P, Sansen S, Mechtler T, Streubel B, Cobos P, Lukacs Z, Kasper D
CLIN GENET. 2020;97(4):655-660.

Graphene quantum dots as cysteine protease nanocarriers against stored grain insect pests
Batool M, Hussain D, Akrem A, Najam-Ul-Haq M, Saeed S, Zaka S, Nawaz M, Buck F, Saeed Q
SCI REP-UK. 2020;10(1):3444.

Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cells
Böckelmann L, Starzonek C, Niehoff A, Karst U, Thomale J, Schlüter H, Bokemeyer C, Aigner A, Schumacher U
HISTOCHEM CELL BIOL. 2020;153(5):367-377.

Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases
Brandt S, Ellinger B, van Nguyen T, Harder S, Schlüter H, Hahnke R, Rühl M, Schäfer W, Gand M
FRONT MICROBIOL. 2020;11:2154.

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
Brenna S, Altmeppen H, Mohammadi B, Rissiek B, Schlink F, Ludewig P, Krisp C, Schlüter H, Failla A, Schneider C, Glatzel M, Puig B, Magnus T
J EXTRACELL VESICLES. 2020;9(1):1809065.

Determinants of Serum- and Plasma Sphingosine-1-Phosphate Concentrations in a Healthy Study Group
Daum G, Winkler M, Moritz E, Müller T, Geffken M, von Lucadou M, Haddad M, Peine S, Böger R, Larena-Avellaneda A, Debus E, Gräler M, Schwedhelm E
TH Open. 2020;4(1):e12-e19.

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets
Deppermann C, Kratofil R, Peiseler M, David B, Zindel J, Castanheira F, van der Wal F, Carestia A, Jenne C, Marth J, Kubes P
J EXP MED. 2020;217(4):.

Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents
Diering S, Stathopoulou K, Goetz M, Rathjens L, Harder S, Piasecki A, Raabe J, Schulz S, Brandt M, Pflaumenbaum J, Fuchs U, Donzelli S, Sadayappan S, Nikolaev V, Flenner F, Ehler E, Cuello F
J BIOL CHEM. 2020;295(45):15342-15365.

Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
Dyshlovoy S, Pelageev D, Hauschild J, Sabutskii Y, Khmelevskaya E, Krisp C, Kaune M, Venz S, Borisova K, Busenbender T, Denisenko V, Schlüter H, Bokemeyer C, Graefen M, Polonik S, Anufriev V, Amsberg G
MAR DRUGS. 2020;18(5):.

Interleukin-6 elevation in healthy neonates
Ebenebe C, Boiger A, Perez A, Mathies F, Hecher K, Singer D
J PERINATOL. 2020;40(2):294-298.

Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study Ex Vivo
Friedrich R, Quade M, Jowett N, Kroetz P, Amling M, Kohlrusch F, Zustin J, Gosau M, SchlÜter H, Miller R
IN VIVO. 2020;34(5):2325-2336.

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, Wiseman J, Eklund L, Martínez-Torrecuadrada J, Vestweber D, Mäkinen T
ELIFE. 2020;9:.

Guiding Opioid Administration by 3 Different Analgesia Nociception Monitoring Indices During General Anesthesia Alters Intraoperative Sufentanil Consumption and Stress Hormone Release: A Randomized Controlled Pilot Study
Funcke S, Pinnschmidt H, Wesseler S, Brinkmann C, Beyer B, Jazbutyte V, Behem C, Trepte C, Nitzschke R
ANESTH ANALG. 2020;130(5):1264-1273.

The cell adhesion molecule L1 interacts with nuclear proteins via its intracellular domain
Girbes Minguez M, Wolters-Eisfeld G, Lutz D, Buck F, Schachner M, Kleene R
FASEB J. 2020;34(8):9869-9883.

Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology
Gnoth K, Piechotta A, Kleinschmidt M, Konrath S, Schenk M, Taudte N, Ramsbeck D, Rieckmann V, Geissler S, Eichentopf R, Barendrecht S, Hartlage-Rübsamen M, Demuth H, Roßner S, Cynis H, Rahfeld J, Schilling S
ALZHEIMERS RES THER. 2020;12(1):149.

The Importance of Mechanical Forces for in vitro Endothelial Cell Biology
Gordon E, Schimmel L, Frye M
FRONT PHYSIOL. 2020;11:684.

Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture
Gulen B, Rosselin M, Fauser J, Albers M, Pett C, Krisp C, Pogenberg V, Schlüter H, Hedberg C, Itzen A
NAT CHEM. 2020;12(8):732-739.

Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
Hassani Nia F, Woike D, Martens V, Klüssendorf M, Hönck H, Harder S, Kreienkamp H
MOL AUTISM. 2020;11(1):85.

Symmetric dimethylarginine in dysfunctional high-density lipoprotein mediates endothelial glycocalyx breakdown in chronic kidney disease
Hesse B, Rovas A, Buscher K, Kusche-Vihrog K, Brand M, Di Marco G, Kielstein J, Pavenstädt H, Linke W, Nofer J, Kümpers P, Lukasz A
KIDNEY INT. 2020;97(3):502-515.

The Tumor Suppressor TFF1 Occurs in Different Forms and Interacts with Multiple Partners in the Human Gastric Mucus Barrier: Indications for Diverse Protective Functions
Heuer J, Heuer F, Stürmer R, Harder S, Schlüter H, Braga Emidio N, Muttenthaler M, Jechorek D, Meyer F, Hoffmann W
INT J MOL SCI. 2020;21(7):.

Hypoxia-Responsive Class III Peroxidases in Maize Roots: Soluble and Membrane-Bound Isoenzymes
Hofmann A, Wienkoop S, Harder S, Bartlog F, Lüthje S
INT J MOL SCI. 2020;21(22):.

LPS-induced expression and release of monocyte tissue factor in patients with haemophilia
Holstein K, Matysiak A, Witt L, Sievers B, Beckmann L, Haddad M, Renné T, Voigtländer M, Langer F
ANN HEMATOL. 2020;99(7):1531-1542.

Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
Horstmann J, Lunelli M, Cazzola H, Heidemann J, Kühne C, Steffen P, Szefs S, Rossi C, Lokareddy R, Wang C, Lemaire L, Hughes K, Uetrecht C, Schlüter H, Grassl G, Stradal T, Rossez Y, Kolbe M, Erhardt M
NAT COMMUN. 2020;11(1):2013.

FLASHDeconv: Ultrafast, High-Quality Feature Deconvolution for Top-Down Proteomics
Jeong K, Kim J, Gaikwad M, Hidayah S, Heikaus L, Schlüter H, Kohlbacher O
CELL SYST. 2020;10(2):213-218.e6.

First Recognized Patient with Genetic Vitamin E Deficiency Stable after 36 Years of Controlled Supplement Therapy
Kohlschütter A, Finckh B, Nickel M, Bley A, Hübner C
NEURODEGENER DIS. 2020;20(1):35-38.

64(th) Annual Congress of the Gesellschaft fur Thrombose- und Hamostaseforschung e.V. in Bremen: Novel Concepts for a Lifetime Challenge
Langer F, Renné T
HAMOSTASEOLOGIE. 2020;40(1):9-11.

64th Annual Congress of the Gesellschaft für Thrombose- und Hämostaseforschung e.V. in Bremen (Part II)
Langer F, Renné T
HAMOSTASEOLOGIE. 2020;40(2):143-144.

Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer
Lange T, Samatov T, Galatenko V, Steffen P, von Kriegstein H, Spethmann T, Wicklein D, Maar H, Kupfernagel K, Labitzky V, Hanika S, Starzonek S, Ahlers A, Riecken K, Simon R, Polonski A, Sauter G, Schlomm T, Huland H, Johnsen S, Schlüter H, Tonevitsky A, Schumacher U
EUR J CANCER. 2020;137:93-107.

At-Risk Testing for Pompe Disease Using Dried Blood Spots: Lessons Learned for Newborn Screening
Lukacs Z, Oliva P, Nieves Cobos P, Scott J, Mechtler T, Kasper D
INT J NEONAT SCREEN. 2020;6(4):.

IPEX as a Consequence of Alternatively Spliced FOXP3
Mailer R
FRONT PEDIATR. 2020;8:594375.

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles
Manuwar A, Dreyer B, Böhmert A, Ullah A, Mughal Z, Akrem A, Ali S, Schluter H, Betzel C
Toxins. 2020;12(11):.

Model prediction of a Kunitz-type trypsin inhibitor protein from seeds of Acacia nilotica L. with strong antimicrobial and insecticidal activity
Mehmood S, Imran M, Ali A, Munawar A, Khaliq B, Anwar F, Saeed Q, Buck F, Hussain S, Saeed A, Yasin Ashraf M, Akrem A
TURK J BIOL. 2020;44(4):188-200.

Reply to Comments on Proteomic Investigations of Two Pakistani Naja Snake Venom Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles. Toxins 2020, 12, 669
Munawar A, Dreyer B, Schlüter H, Betzel C
Toxins. 2020;12(12):.

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways
Noubouossie D, Henderson M, Mooberry M, Ilich A, Ellsworth P, Piegore M, Skinner S, Pawlinski R, Welsby I, Renné T, Hoffman M, Monroe D, Key N
BLOOD. 2020;135(10):755-765.

Investigation of the impact of magnesium versus titanium implants on protein composition in osteoblast by label free quantification
Omidi M, Ahmad Agha N, Müller A, Feyerabend F, Helmholz H, Willumeit-Römer R, Schlüter H, Luthringer-Feyerabend B
METALLOMICS. 2020;12(6):916-934.

In-depth characterization of monocyte subsets during the course of healthy pregnancy
Pflitsch C, Feldmann C, Richert L, Hagen S, Diemert A, Goletzke J, Hecher K, Jazbutyte V, Renné T, Arck P, Altfeld M, Ziegler S
J REPROD IMMUNOL. 2020;141:103151.

Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients
Pflüger L, Bannasch J, Brehm T, Pfefferle S, Hoffmann A, Nörz D, van der Meirschen M, Kluge S, Haddad M, Pischke S, Hiller J, Addo M, Lohse A, Wiesch J, Peine S, Aepfelbacher M, Lütgehetmann M
J CLIN VIROL. 2020;130:104549.

ELF5 modulates the estrogen receptor cistrome in breast cancer
Piggin C, Roden D, Law A, Molloy M, Krisp C, Swarbrick A, Naylor M, Kalyuga M, Kaplan W, Oakes S, Gallego-Ortega D, Clark S, Carroll J, Bartonicek N, Ormandy C
PLOS GENET. 2020;16(1):e1008531.

N-terminal VP1 Truncations Favor T = 1 Norovirus-Like Particles
Pogan R, Weiss V, Bond K, Dülfer J, Krisp C, Lyktey N, Müller-Guhl J, Zoratto S, Allmaier G, Jarrold M, Muñoz-Fontela C, Schlüter H, Uetrecht C
VACCINES-BASEL. 2020;9(1):.

Impact of S1P Mimetics on Mesenteric Ischemia/Reperfusion Injury
Potì F, Giorgio C, Zini I, Nofer J, Vivo V, Palese S, Ballabeni V, Barocelli E, Bertoni S
PHARMACEUTICALS-BASE. 2020;13(10):.

Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication
Puhach O, Ostermann E, Krisp C, Frascaroli G, Schlüter H, Brinkmann M, Brune W
PLOS PATHOG. 2020;16(10):e1008546.

Kinins: https://www.springer.com/gp/book/9783540389163
Renne T, Herwald H
2020. Encyclopedia of Molecular Pharmacology. Springer, 1 - 13.

Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100® in patients undergoing neuroendovascular procedures
Rolling C, Tomada J, Frölich A, Holst B, Holstein K, Voigtländer M, Janjetovic S, Haddad M, Renné T, Fiehler J, Bokemeyer C, Rolling T, Langer F
CLIN CHEM LAB MED. 2020;59(2):383-392.

PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression
Sahni S, Krisp C, Molloy M, Nahm C, Maloney S, Gillson J, Gill A, Samra J, Mittal A
BBA-GEN SUBJECTS. 2020;1864(11):129682.

Identification of Novel Biomarkers in Pancreatic Tumor Tissue to Predict Response to Neoadjuvant Chemotherapy
Sahni S, Nahm C, Krisp C, Molloy M, Mehta S, Maloney S, Itchins M, Pavlakis N, Clarke S, Chan D, Gill A, Howell V, Samra J, Mittal A
FRONT ONCOL. 2020;10:237.

Cell Banking of hiPSCs: A Practical Guide to Cryopreservation and Quality Control in Basic Research
Shibamiya A, Schulze E, Krauß D, Augustin C, Reinsch M, Schulze M, Steuck S, Mearini G, Mannhardt I, Schulze T, Klampe B, Werner T, Saleem U, Knaust A, Laufer S, Neuber C, Lemme M, Behrens C, Loos M, Weinberger F, Fuchs S, Eschenhagen T, Hansen A, Ulmer B
Current protocols in stem cell biology. 2020;55(1):e127.

Heart Failure Results in Inspiratory Muscle Dysfunction Irrespective of Left Ventricular Ejection Fraction
Spiesshoefer J, Henke C, Kabitz H, Bengel P, Schütt K, Nofer J, Spieker M, Orwat S, Diller G, Strecker J, Giannoni A, Dreher M, Randerath W, Boentert M, Tuleta I
RESPIRATION. 2020;100(2):96-108.

Respiratory Muscle and Lung Function in Lung Allograft Recipients: Association with Exercise Intolerance
Spiesshoefer J, Henke C, Kabitz H, Nofer J, Mohr M, Evers G, Strecker J, Brix T, Randerath W, Herkenrath S, Schmidt L, Boentert M
RESPIRATION. 2020;99(5):398-408.

Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
Starzonek S, Maar H, Labitzky V, Wicklein D, Rossdam C, Buettner F, Wolters-Eisfeld G, Guengoer C, Wagener C, Schumacher U, Lange T
GLYCOBIOLOGY. 2020;30(9):695-709.

OmixLitMiner: A Bioinformatics Tool for Prioritizing Biological Leads from 'Omics Data Using Literature Retrieval and Data Mining
Steffen P, Wu J, Hariharan S, Voss H, Raghunath V, Molloy M, Schlüter H
INT J MOL SCI. 2020;21(4):.

Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung
Tuku B, Stanelle-Bertram S, Sellau J, Beck S, Bai T, Kouassi N, Preuß A, Hoenow S, Renné T, Lotter H, Gabriel G
FRONT IMMUNOL. 2020;11:697.

NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects
Vara D, Tarafdar A, Celikag M, Patinha D, Gulacsy C, Hounslea E, Warren Z, Ferreira B, Koeners M, Caggiano L, Pula G
FASEB J. 2020;34(10):13959-13977.

Fibrillar amyloid peptides promote platelet aggregation through the coordinated action of itam- and ros-dependent pathways
Visconte C, Canino J, Vismara M, Francesco Guidetti G, Raimondi S, Pula G, Torti M, Canobbio I
J THROMB HAEMOST. 2020;18(11):3029-3042.

Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice
Vorbach S, Gründer A, Zhou F, Koellerer C, Jutzi J, Simoni M, Riccetti L, Valk P, Sanders M, Müller-Tidow C, Nofer J, Pahl H, Potì F
LEUKEMIA. 2020;34(3):721-734.

Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer
Voß H, Wurlitzer M, Smit D, Ewald F, Alawi M, Spohn M, Indenbirken D, Omidi M, David K, Juhl H, Simon R, Sauter G, Fischer L, Izbicki J, Molloy M, Nashan B, Schlüter H, Jücker M
CLIN EXP METASTAS. 2020;37(6):649-656.

Investigating the suitability of high-resolution mass spectrometry for newborn screening: identification of hemoglobinopathies and β-thalassemias in dried blood spots
Wiesinger T, Mechtler T, Schwarz M, Xie X, Grosse R, Nieves Cobos P, Kasper D, Lukacs Z
CLIN CHEM LAB MED. 2020;58(5):810-816.

Mass Spectrometric Lipid Profiles of Picosecond Infrared Laser-Generated Tissue Aerosols Discriminate Different Brain Tissues
Wurlitzer M, Hessling E, Rinas K, Fuh M, Petersen H, Ricklefs F, Lamszus K, Regelsberger J, Maier S, Kruber S, Hansen N, Miller R, Schlüter H
LASER SURG MED. 2020;52(3):228-234.

Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
Wurlitzer M, Möckelmann N, Kriegs M, Vens M, Omidi M, Hoffer K, Bargen C, Möller-Koop C, Witt M, Droste C, Oetting A, Petersen H, Busch C, Münscher A, Schlüter H, Clauditz T, Rieckmann T
CANCERS. 2020;12(6):.

Interleukin-9 protects from early podocyte injury and progressive glomerulosclerosis in Adriamycin-induced nephropathy
Xiong T, Attar M, Gnirck A, Wunderlich M, Becker M, Rickassel C, Puelles V, Meyer-Schwesinger C, Wiech T, Nies J, Divivier M, Fuchs T, Schulze Zur Wiesch J, Taipaleenmäki H, Hoxha E, Wirtz S, Huber T, Panzer U, Turner J
KIDNEY INT. 2020;98(3):615-629.

Boronic acid-functionalized mesoporous magnetic particles with a hydrophilic surface for the multimodal enrichment of glycopeptides for glycoproteomics
Yang L, Zhang Q, Huang Y, Lin L, Schlüter H, Wang K, Zhang C, Yang P, Yu H
ANALYST. 2020;145(15):5252-5259.

Lipidomic profiling of virus infection identifies mediators that resolve herpes simplex virus-induced corneal inflammatory lesions
Zhang C, Hu Z, Wang K, Yang L, Li Y, Schlüter H, Yang P, Hong J, Yu H
ANALYST. 2020;145(11):3967-3976.

Social work support and unmet social needs in life after stroke: a cross-sectional exploratory study

BMC NEUROL. 2019;19(1):220.

Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting
Ahmed M, Gustafsson B, Aldi S, Dusart P, Egri G, Butler L, Bone D, Dähne L, Hedin U, Caidahl K
CELL MOL BIOENG. 2019;12(1):15-32.

Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging
Amirbeigiarab S, Kiani P, Velazquez Sanchez A, Krisp C, Kazantsev A, Fester L, Schlüter H, Ignatova Z
P NATL ACAD SCI USA. 2019;116(45):22567-22572.

Quantitation of Glycopeptides by ESI/MS - size of the peptide part strongly affects the relative proportions and allows discovery of new glycan compositions of Ceruloplasmin
Baerenfaenger M, Moritz M, Meyer B
GLYCOCONJUGATE J. 2019;36(1):13-26.

In vitro proinflammatory gene expression changes in human whole blood after contact with plasma-treated implant surfaces
Becker M, Quabius S, Kewitz T, Hansen L, Becker G, Kern M, Kersten H, Harder S
J CRANIO MAXILL SURG. 2019;47(8):1255-1261.

Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients
Brinkkoetter P, Grundmann F, Ghassabeh P, Becker I, Johnsen M, Suaréz V, Schulz R, Streichert T, Burst V
SCI REP-UK. 2019;9(1):12526.

Design and characterization of α1-antitrypsin variants for treatment of contact system-driven thromboinflammation
de Maat S, Sanrattana W, Mailer R, Parr N, Hessing M, Koetsier R, Meijers J, Pasterkamp G, Renné T, Maas C
BLOOD. 2019;134(19):1658-1669.

Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis
Deniset J, Belke D, Lee W, Jorch S, Deppermann C, Hassanabad A, Turnbull J, Teng G, Rozich I, Hudspeth K, Kanno Y, Brooks S, Hadjantonakis A, O'Shea J, Weber G, Fedak P, Kubes P
IMMUNITY. 2019;51(1):131-140.e5.

A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes
Dusart P, Hallström B, Renné T, Odeberg J, Uhlén M, Butler L
CELL REP. 2019;29(6):1690-1706.e4.

Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
Dyshlovoy S, Pelageev D, Hauschild J, Borisova K, Kaune M, Krisp C, Venz S, Sabutskii Y, Khmelevskaya E, Busenbender T, Denisenko V, Pokhilo N, Atopkina L, Graefen M, Schlüter H, Stonik V, Bokemeyer C, Anufriev V, von Amsberg G
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Diagnostic accuracy of interleukin-6 for early-onset sepsis in preterm neonates
Ebenebe C, Hesse F, Blohm M, Jung R, Kunzmann S, Singer D
J MATERN-FETAL NEO M. 2019 [Epub ahead of print];1-6.

Antimicrobial peptides derived from the cartilage.-specific C-type Lectin Domain Family 3 Member A (CLEC3A) - potential in the prevention and treatment of septic arthritis
Elezagic D, Mörgelin M, Hermes G, Hamprecht A, Sengle G, Lau D, Höllriegl S, Wagener R, Paulsson M, Streichert T, Klatt A
OSTEOARTHR CARTILAGE. 2019;27(10):1564-1573.

Structural and In Vitro Functional Comparability Analysis of Altebrel™, a Proposed Etanercept Biosimilar: Focus on Primary Sequence and Glycosylation
Fazel R, Guan Y, Vaziri B, Krisp C, Heikaus L, Saadati A, Nurul Hidayah S, Gaikwad M, Schlüter H
PHARMACEUTICALS-BASE. 2019;12(1):.

Metabolic Activity in Central Neural Structures of Patients With Myocardial Injury
Fiechter M, Roggo A, Haider A, Bengs S, Burger I, Marędziak M, Portmann A, Treyer V, Becker A, Messerli M, Mühlematter U, Kudura K, von Felten E, Benz D, Fuchs T, Gräni C, Pazhenkottil A, Buechel R, Kaufmann P, Gebhard C
J AM HEART ASSOC. 2019;8(19):e013070.

Cytomegalovirus (CMV) Pneumonitis: Cell Tropism, Inflammation, and Immunity
Fonseca Brito L, Brune W, Stahl F
INT J MOL SCI. 2019;20(16):3865.

Newborn Screening for Lysosomal Storage Disorders: Methodologies for Measurement of Enzymatic Activities in Dried Blood Spots
Gelb M, Lukacs Z, Ranieri E, Schielen P
INT J NEONAT SCREEN. 2019;5(1):.

Acute Lung Injury: IL-17A-Mediated Inflammatory Pathway and Its Regulation by Curcumin
Gouda M, Bhandary Y
INFLAMMATION. 2019;42(4):1160-1169.

Precision and reliability of liver iodine quantification from spectral detector CT: evidence from phantom and patient data
Große Hokamp N, Abdullayev N, Persigehl T, Schlaak M, Wybranski C, Holz J, Streichert T, Alkadhi H, Maintz D, Haneder S
EUR RADIOL. 2019;29(4):2098-2106.

Mass spectrometry-based intraoperative tumor diagnostics
Hänel L, Kwiatkowski M, Heikaus L, Schlüter H
FUTUR SCI OA. 2019;5(3):FSO373.

Changes in proinflammatory gene expression in human whole blood after contact with UV-conditioned implant surfaces
Harder S, Quabius E, Meinke F, Mehl C, Kern M
CLIN ORAL INVEST. 2019;23(10):3731-3738.

Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils
Heestermans M, Salloum-Asfar S, Streef T, Laghmani E, Salvatori D, Luken B, Zeerleder S, Spronk H, Korporaal S, Kirchhofer D, Wagenaar G, Versteeg H, Reitsma P, Renné T, van Vlijmen B
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Different Forms of TFF3 in the Human Saliva: Heterodimerization with IgG Fc Binding Protein (FCGBP)
Houben T, Harder S, Schlüter H, Kalbacher H, Hoffmann W
INT J MOL SCI. 2019;20(20):.

Peritoneal GATA6+ macrophages function as a portal for Staphylococcus aureus dissemination
Jorch S, Surewaard B, Hossain M, Peiseler M, Deppermann C, Deng J, Bogoslowski A, van der Wal F, Omri A, Hickey M, Kubes P
J CLIN INVEST. 2019;129(11):4643-4656.

Neutrophils engage the kallikrein-kinin system to open up the endothelial barrier in acute inflammation
Kenne E, Rasmuson J, Renné T, Vieira M, Müller-Esterl W, Herwald H, Lindbom L
FASEB J. 2019;33(2):2599-2609.

Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases
Kiran Gotru S, van Geffen J, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns H, Heemskerk J, Braun A
SCI REP-UK. 2019;9(1):8333.

Vitamin D receptor expression and serum 25(OH)D concentration inversely associates with burden of neurofibromas
Kluwe L, Hagel C, Friedrich R, Schnabel C, Schön G, Mautner V
EUR J CANCER PREV. 2019;28(3):220-224.

Obstructive sleep apnea and craniofacial appearance in MPS type I-Hurler children after hematopoietic stem cell transplantation
Koehne T, Müller-Stöver S, Köhn A, Stumpfe K, Lezius S, Schmid C, Lukacs Z, Kahl-Nieke B, Muschol N
SLEEP BREATH. 2019;23(4):1315-1321.

Sampling of Tissues with Laser Ablation for Proteomics: Comparison of Picosecond Infrared Laser and Microsecond Infrared Laser
Krutilin A, Maier S, Schuster R, Kruber S, Kwiatkowski M, Robertson W, Hansen N, Miller R, Schlüter H
J PROTEOME RES. 2019;18(3):1451-1457.

Clotting factor activity in fresh frozen plasma after thawing with a new radio wave thawing device
Kuta P, Melling N, Zimmermann R, Achenbach S, Eckstein R, Strobel J
TRANSFUSION. 2019;59(5):1857-1861.

Probennahme per Laserablation von Krebsgeweben für Proteomics
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BIOspektrum. 2019;25(1):32-34.

Polyphosphate as a Target for Interference With Inflammation and Thrombosis
Mailer R, Hänel L, Allende M, Renné T
FRONT MED-LAUSANNE. 2019;6:76.

Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation
Martínez Sánchez A, Omidi M, Wurlitzer M, Fuh M, Feyerabend F, Schlüter H, Willumeit-Römer R, Luthringer B
BIOACT MATER. 2019;4:168-188.

The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP
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Liquid application method for time-resolved analyses by serial synchrotron crystallography
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Time-resolved crystallography reveals allosteric communication aligned with molecular breathing
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SCIENCE. 2019;365(6458):1167-1170.

International Society on Thrombosis and Haemostasis core curriculum project: core competencies in laboratory thrombosis and hemostasis
Moffat K, Kiencke V, Blanco A, McLintock C, Peyvandi F, de Maat M, Adams M, Angchaisuksiri P, Nair S, Tsuda H, Haddad M, Renné T, Clark R, Ross M
J THROMB HAEMOST. 2019;17(11):1848-1859.

Neutrophil Extracellular Traps Initiate Gallstone Formation
Muñoz L, Boeltz S, Bilyy R, Schauer C, Mahajan A, Widulin N, Grüneboom A, Herrmann I, Boada E, Rauh M, Krenn V, Biermann M, Podolska M, Hahn J, Knopf J, Maueröder C, Paryzhak S, Dumych T, Zhao Y, Neurath M, Hoffmann M, Fuchs T, Leppkes M, Schett G, Herrmann M
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Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs
Naujokat H, Harder S, Schulz L, Wiltfang J, Flörke C, Açil Y
J CRANIO MAXILL SURG. 2019;47(3):484-490.

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction
Neumann J, Twerenbold R, Ojeda F, Sörensen N, Chapman A, Shah A, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering J, Troughton R, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus H, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario M, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner K, Worster A, Body R, Ekelund U, Kavsak P, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen L, Mills N, Mueller C, Zeller T, Westermann D, Blankenberg S
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Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry
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Roles of Factor XII in Innate Immunity
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FRONT IMMUNOL. 2019;10:2011.

High Aldehyde Dehydrogenase Levels Are Detectable in the Serum of Patients with Lung Cancer and May Be Exploited as Screening Biomarkers
Rossi A, Voigtländer M, Klose H, Schlüter H, Schön G, Loges S, Paolini M, Bokemeyer C, Reck M, Tarro G, Binder M
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TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone
Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jähn K, Long C, Schlüter H, Kwiatkowski M, Saini V, Pajevic P, Bellido T, van Wijnen A, Mohammad K, Guise T, Taipaleenmäki H, Hesse E
NAT COMMUN. 2019;10(1):1354.

Off-label application of intravenous immunoglobulin (IVIG) for treatment of Cogan's syndrome during pregnancy
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BMJ CASE REP. 2019;12(10):.

Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis
Schluter M, Fuh M, Maier S, Otte C, Kiani P, Hansen N, Dwayne Miller R, Schluter H, Schlaefer A
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Nomenclature of factor XI and the contact system
Schmaier A, Emsley J, Feener E, Gailani D, Govers-Riemslag J, Kaplan A, Maas C, Morrissey J, Renné T, Sidelmann J, Meijers J
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A five-level classification system for proteoform identifications
Smith L, Thomas P, Shortreed M, Schaffer L, Fellers R, LeDuc R, Tucholski T, Ge Y, Agar J, Anderson L, Chamot-Rooke J, Gault J, Loo J, Paša-Tolić L, Robinson C, Schlüter H, Tsybin Y, Vilaseca M, Vizcaíno J, Danis P, Kelleher N
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Reciprocal Multifaceted Interaction Between HDL (High-Density Lipoprotein) and Myocardial Infarction
Sposito A, de Lima-Junior J, Moura F, Barreto J, Bonilha I, Santana M, Virginio V, Sun L, Carvalho L, Soares A, Nadruz W, Feinstein S, Nofer J, Zanotti I, Kontush A, Remaley A
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Native mass spectrometry provides sufficient ion flux for XFEL single-particle imaging
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J SYNCHROTRON RADIAT. 2019;26(Pt 3):653-659.

A novel combinatorial technique for simultaneous quantification of oxygen radicals and aggregation reveals unexpected redox patterns in the activation of platelets by different physiopathological stimuli
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Recommendations for clinical monitoring of patients with acid sphingomyelinase deficiency (ASMD)
Wasserstein M, Dionisi-Vici C, Giugliani R, Hwu W, Lidove O, Lukacs Z, Mengel E, Mistry P, Schuchman E, McGovern M
MOL GENET METAB. 2019;126(2):98-105.

Proteome profiling of Pseudomonas aeruginosa PAO1 identifies novel responders to copper stress
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BMC MICROBIOL. 2019;19(1):69.

Proteomics of the corpus callosum to identify novel factors involved in hypomyelinated Niemann-Pick Type C disease mice
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Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level
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Specificity of late-night salivary cortisol measured by automated electrochemiluminescence immunoassay for Cushing's disease in an obese population
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How many human proteoforms are there?
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Understanding Protein Networks using Vester's Sensitivity Model
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Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Benten D, Behrang Y, Unrau L, Weissmann V, Wolters-Eisfeld G, Burdak-Rothkamm S, Stahl F, Anlauf M, Grabowski P, Möbs M, Dieckhoff J, Sipos B, Fahl M, Eggers C, Perez D, Bockhorn M, Izbicki J, Lohse A, Schrader J
MOL CANCER RES. 2018;16(3):496-507.

Discordant prostate specific antigen test results despite WHO assay standardization
Boegemann M, Arsov C, Hadaschik B, Herkommer K, Imkamp F, Nofer J, Gerß J, Albers P, Semjonow A
INT J BIOL MARKER. 2018;33(3):275-282.

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, Dobert J, Pavlenko E, Schumacher N, Renné T, Taylor P, Linder S, Rose-John S, Zunke F
J IMMUNOL. 2018;201(10):3106-3118.

Platelets and vascular integrity
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Start a fire, kill the bug: The role of platelets in inflammation and infection
Deppermann C, Kubes P
INNATE IMMUN-LONDON. 2018;24(6):335-348.

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein
Dusart P, Fagerberg L, Perisic L, Civelek M, Struck E, Hedin U, Uhlén M, Trégouët D, Renné T, Odeberg J, Butler L
SCI REP-UK. 2018;8(1):14668.

Elevating Endogenous Sphingosine-1-Phosphate (S1P) Levels Improves Endothelial Function and Ameliorates Atherosclerosis in Low Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice
Feuerborn R, Besser M, Potì F, Burkhardt R, Weißen-Plenz G, Ceglarek U, Simoni M, Proia R, Freise H, Nofer J
THROMB HAEMOSTASIS. 2018;118(8):1470-1480.

Neutrophil Extracellular Traps
Fuchs T, Hakkim A, Urban C
2018. Inflammation: Fundamental Mechanisms. Ley K (Hrsg.). 1. Aufl. World Scientific Publishing Co. Pte Ltd, 205-276.

Endothelial barrier function is differentially regulated by CEACAM1-mediated signaling
Ghavampour S, Kleefeldt F, Bömmel H, Volland J, Paus A, Horst A, Pfeiffer V, Hübner S, Wagner N, Rueckschloss U, Ergün S
FASEB J. 2018;32(10):5612-5625.

LDL-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice.
Gisterå A, Maria L K, Polyzos K, Mailer R, Duhlin A, Karlsson M, Ketelhuth D, Hansson G
CIRCULATION. 2018;138(22):2513-2526.

Human cytomegalovirus replication induces endothelial cell interleukin-11
Gustafsson K, Renné T, Söderberg-Naucler C, Butler L
CYTOKINE. 2018;111:563-566.

Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases
Hänel L, Gosau T, Maar H, Valentiner U, Schumacher U, Riecken K, Windhorst S, Hansen N, Heikaus L, Wurlitzer M, Nolte I, Schlüter H, Lange T
SCI REP-UK. 2018;8(1):13986.

Impact of systemic inhibition on ocular levels of angiotensin-converting enzyme (ACE)
Hoerster R, Cursiefen C, Streichert T, Heindl L
GRAEF ARCH CLIN EXP. 2018;256(12):2487-2488.

CEACAM1 in Liver Injury, Metabolic and Immune Regulation
Horst A, Najjar S, Wagener C, Tiegs G
INT J MOL SCI. 2018;19(10):3110.

Correction: Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue
Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt M, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A
PLOS ONE. 2018;13(11):e0208342.

Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism
Jiménez-Alcázar M, Limacher A, Panda R, Méan M, Bitterling J, Peine S, Renné T, Beer J, Aujesky D, Lämmle B, Fuchs T
PLOS ONE. 2018;13(2):e0191150.

Indirect methods for reference interval determination - review and recommendations
Jones G, Haeckel R, Loh T, Sikaris K, Streichert T, Katayev A, Barth J, Ozarda Y
CLIN CHEM LAB MED. 2018;57(1):20-29.

The Simultaneous measurement of serum testosterone and 5α-dihydrotestosterone by gas chromatography-mass spectrometry (GC-MS)
Kannenberg F, Fobker M, Schulte E, Pierściński G, Kelsch R, Zitzmann M, Nofer J, Schüring A
CLIN CHIM ACTA. 2018;476:15-24.

Proteomic phenotyping of metastatic melanoma reveals putative signatures of MEK inhibitor response and prognosis
Krisp C, Parker R, Pascovici D, Hayward N, Wilmott J, Thompson J, Mann G, Long G, Scolyer R, Molloy M
BRIT J CANCER. 2018;119(6):713-723.

Application of Displacement Chromatography to Online Two-Dimensional Liquid Chromatography Coupled to Tandem Mass Spectrometry Improves Peptide Separation Efficiency and Detectability for the Analysis of Complex Proteomes
Kwiatkowski M, Krösser D, Wurlitzer M, Steffen P, Barcaru A, Krisp C, Horvatovich P, Bischoff R, Schlüter H
ANAL CHEM. 2018;90(16):9951-9958.

A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate
Labberton L, Long A, Gendler S, Snozek C, Stavrou E, Nickel K, Maas C, Blankenberg S, Hernandez J, Renné T
CYTOM PART B-CLIN CY. 2018;94(2):369-373.

Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss
Lautenbach A, Wernecke M, Riedel N, Veigel J, Yamamura J, Keller S, Jung R, Busch P, Mann O, Knop F, Holst J, Meier J, Aberle J
DIABETES-METAB RES. 2018;34(7):e3025.

BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells
Lessel D, Gehbauer C, Bramswig N, Schluth-Bolard C, Venkataramanappa S, van Gassen K, Hempel M, Haack T, Baresic A, Genetti C, Funari M, Lessel I, Kuhlmann L, Simon R, Liu P, Denecke J, Kuechler A, de Kruijff I, Shoukier M, Lek M, Mullen T, Lüdecke H, Lerario A, Kobbe R, Krieger T, Demeer B, Lebrun M, Keren B, Nava C, Buratti J, Afenjar A, Shinawi M, Guillen Sacoto M, Gauthier J, Hamdan F, Laberge A, Campeau P, Louie R, Cathey S, Prinz I, Jorge A, Terhal P, Lenhard B, Wieczorek D, Strom T, Agrawal P, Britsch S, Tolosa E, Kubisch C
BRAIN. 2018;141(8):2299-2311.

Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells
Lueder Y, Heller K, Ritter C, Keyser K, Wagner K, Liu X, Messerle M, Stahl F, Halle S, Förster R
PLOS PATHOG. 2018;14(8):e1007252.

Coagulation factor XII in thrombosis and inflammation
Maas C, Renné T
BLOOD. 2018;131(17):1903-1909.

Alternative Splicing of FOXP3-Virtue and Vice
Mailer R
FRONT IMMUNOL. 2018;9:530.

What a drag - necrotic platelets induce remote neutrophil thrombi following ischemic gut injury
Martinod K, Fuchs T
J THROMB HAEMOST. 2018;16(5):819-821.

Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum
Müller C, Fietz C, Koehler P, Sibley G, Nforbugwe A, Streichert T, Wiesen M
ANTIMICROB AGENTS CH. 2018;62(11):.

Distinguishing reference intervals and clinical decision limits - A review by the IFCC Committee on Reference Intervals and Decision Limits
Ozarda Y, Sikaris K, Streichert T, Macri J
CRIT REV CL LAB SCI. 2018;55(6):420-431.

Picosecond Infrared Laser (PIRL) Application in Stapes Surgery-First Experience in Human Temporal Bones
Petersen H, Gliese A, Stober Y, Maier S, Hansen N, Kruber S, Eggert D, Tóth M, Gosau T, Schlüter H, Püschel K, Schumacher U, Miller R, Münscher A, Dalchow C
OTOL NEUROTOL. 2018;39(4):e224-e230.

Computational modeling and functional characterization of a GgChi: A class III chitinase from corms of Gladiolus grandiflorus
Rafiq M, Hussain A, Shah K, Saeed Q, Sial M, Ali Z, Buck F, Goodman R, Khaliq B, Ishaq U, Baig M, Munawar A, Mahmood S, Akrem A
KAOHSIUNG J MED SCI. 2018;34(12):673-683.

Isolation and initial structural characterization of a 27 kDa protein from Zingiber officinale.
Rasheed S, Ahmad M, Falke S, Arslan A, Fazel R, Schlüter H, Betzel C, Choudhary
J MOL STRUCT. 2018;1156:330-335.

Low Prevalence Estimates of Late-Onset Glycogen Storage Disease Type II in French-Speaking Belgium are not Due to Missed Diagnoses
Remiche G, Lukacs Z, Kasper D, Abramowicz M, Pandolfo M
J NEUROMUSCULAR DIS. 2018;5(4):471-480.

New frontiers in drug development utilizing desorption by impulsive vibrational excitation for sample preparation, tissue imaging and beyond
Robertson W, Schlüter H, Miller R, Ji Q
BIOANALYSIS. 2018;10(20):1625-1629.

Value of early postoperative random growth hormone levels and nadir growth hormone levels after oral glucose tolerance testing in acromegaly
Rotermund R, Burkhardt T, Rohani Z, Jung R, Aberle J, Flitsch J
GROWTH HORM IGF RES. 2018;41:64-70.

Identification of antibodies against extracellular matrix proteins in human osteoarthritis
Ruthard J, Hermes G, Hartmann U, Sengle G, Pongratz G, Ostendorf B, Schneider M, Höllriegl S, Zaucke F, Wagener R, Streichert T, Klatt A
BIOCHEM BIOPH RES CO. 2018;503(3):1273-1277.

Detection of annexin A8 antibodies in serum of patients with antiphospholipid syndrome
Scholz P, Auler M, Ruthard J, Brachvogel B, Klatt A, Streichert T
BIOCHEM MEDICA. 2018;28(3):030703.

The hit-and-return system enables efficient time-resolved serial synchrotron crystallography
Schulz E, Mehrabi P, Müller-Werkmeister H, Tellkamp F, Jha A, Stuart W, Persch E, De Gasparo R, Diederich F, Pai E, Miller R
NAT METHODS. 2018;15(11):901-904.

Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis
Spronk H, Padro T, Siland J, Prochaska J, Winters J, van der Wal A, Posthuma J, Lowe G, d'Alessandro E, Wenzel P, Coenen D, Reitsma P, Ruf W, van Gorp R, Koenen R, Vajen T, Alshaikh N, Wolberg A, Macrae F, Asquith N, Heemskerk J, Heinzmann A, Moorlag M, Mackman N, van der Meijden P, Meijers J, Heestermans M, Renné T, Dólleman S, Chayouâ W, Ariëns R, Baaten C, Nagy M, Kuliopulos A, Posma J, Harrison P, Vries M, Crijns H, Dudink E, Buller H, Henskens Y, Själander A, Zwaveling S, Erküner O, Eikelboom J, Gulpen A, Peeters F, Douxfils J, Olie R, Baglin T, Leader A, Schotten U, Scaf B, van Beusekom H, Mosnier L, van der Vorm L, Declerck P, Visser M, Dippel D, Strijbis V, Pertiwi K, Ten Cate-Hoek A, Ten Cate H
THROMB HAEMOSTASIS. 2018;118(2):229-250.

Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis
Stahl F, Jung R, Jazbutyte V, Ostermann E, Tödter S, Brixel R, Kemmer A, Halle S, Rose-John S, Messerle M, Arck P, Brune W, Renné T
SCI REP-UK. 2018;8(1):14823.

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood
Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante I, Dreier C, Kouassi N, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V, Gerhauser I, Pfankuche V, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese M, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter S, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G
NAT MICROBIOL. 2018;3(10):1161-1174.

Factor XII and uPAR upregulate neutrophil functions to influence wound healing
Stavrou E, Fang C, Bane K, Long A, Naudin C, Kucukal E, Gandhi A, Brett-Morris A, Mumaw M, Izadmehr S, Merkulova A, Reynolds C, Alhalabi O, Nayak L, Yu W, Qu C, Meyerson H, Dubyak G, Gurkan U, Nieman M, Sen Gupta A, Renné T, Schmaier A
J CLIN INVEST. 2018;128(3):944-959.

Commercial Porcine Gastric Mucin Preparations, also Used as Artificial Saliva, are a Rich Source for the Lectin TFF2: In Vitro Binding Studies
Stürmer R, Harder S, Schlüter H, Hoffmann W
CHEMBIOCHEM. 2018;19(24):2598-2608.

α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis
Surewaard B, Thanabalasuriar A, Zeng Z, Tkaczyk C, Cohen T, Bardoel B, Jorch S, Deppermann C, Bubeck Wardenburg J, Davis R, Jenne C, Stover K, Sellman B, Kubes P
CELL HOST MICROBE. 2018;24(2):271-284.e3.

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders
Tarafdar A, Pula G
INT J MOL SCI. 2018;19(12):.

Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis
Vara D, Watt J, Fortunato T, Mellor H, Burgess M, Wicks K, Mace K, Reeksting S, Lubben A, Wheeler-Jones C, Pula G
ANTIOXID REDOX SIGN. 2018;28(2):110-130.

Amyloid precursor protein is required for in vitro platelet adhesion to amyloid peptides and potentiation of thrombus formation
Visconte C, Canino J, Guidetti G, Zarà M, Seppi C, Abubaker A, Pula G, Torti M, Canobbio I
CELL SIGNAL. 2018;52:95-102.

CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells
Wicklein D, Otto B, Suling A, Elies E, Lüers G, Lange T, Feldhaus S, Maar H, Schröder-Schwarz J, Brunner G, Wagener C, Schumacher U
SCI REP-UK. 2018;8:11893.

Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice
Wolters-Eisfeld G, Mercanoglu B, Hofmann B, Wolpers T, Schnabel C, Harder S, Steffen P, Bachmann K, Steglich B, Schrader J, Gagliani N, Schlüter H, Güngör C, Izbicki J, Wagener C, Bockhorn M
EXP MOL MED. 2018;50(10):1-13.

Innate immune responses to toll-like receptor stimulation are altered during the course of pregnancy
Ziegler S, Feldmann C, Hagen S, Richert L, Barkhausen T, Goletzke J, Jazbutyte V, Martrus G, Salzberger W, Renné T, Hecher K, Diemert A, Arck P, Altfeld M
J REPROD IMMUNOL. 2018;128(SI):30-37.

Prognostic value of early S100B protein and Neuron-specific Enolase in patients with poor grade aneurysmal subarachnoid hemorrhage, a pilot study
Abboud T, Mende K, Jung R, Czorlich P, Vettorazzi E, Priefler M, Kluge S, Westphal M, Regelsberger J
WORLD NEUROSURG. 2017;108:669-675.

Factor XII-Driven Inflammatory Reactions with Implications for Anaphylaxis
Bender L, Weidmann H, Rose-John S, Renné T, Long A
FRONT IMMUNOL. 2017;8:1115.

Semiconductor technology in protein kinase research and drug discovery: sensing a revolution
Bhalla N, Di Lorenzo M, Estrela P, Pula G
DRUG DISCOV TODAY. 2017;22(2):204-209.

Novel targets for anticoagulants lacking bleeding risk
Bickmann J, Baglin T, Meijers J, Renné T
CURR OPIN HEMATOL. 2017;24(5):419-426.

Cross-talk between inflammation and coagulation
Bickmann J, Kiencke V, Long A, Renne T
2017. Hematology Education, 2017. 188 - 190.

Neutrophil Extracellular Traps Open the Pandora's Box in Severe Malaria
Boeltz S, Muñoz L, Fuchs T, Herrmann M
FRONT IMMUNOL. 2017;8:874.

Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats
Boettcher M, Eschenburg G, Mietzsch S, Jiménez-Alcázar M, Klinke M, Vincent D, Tiemann B, Bergholz R, Reinshagen K, Fuchs T
SCI REP-UK. 2017;7(1):15377.

Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage after Testicular Torsion in Rats
Boettcher M, Meier D, Jiménez-Alcázar M, Eschenburg G, Mietzsch S, Vincent D, Klinke M, Trochimiuk M, Appl B, Tiemann B, Bergholz R, Reinshagen K, Fuchs T
UROLOGY. 2017;109:223.e1-223.e7.

Criteria for assigning laboratory measurands to models for analytical performance specifications defined in the 1st EFLM Strategic Conference
Ceriotti F, Fernandez-Calle P, Klee G, Nordin G, Sandberg S, Streichert T, Vives-Corrons J, Panteghini M
CLIN CHEM LAB MED. 2017;55(2):189-194.

"Molecular Activity Painting": Switch-like, Light-Controlled Perturbations inside Living Cells
Chen X, Venkatachalapathy M, Kamps D, Weigel S, Kumar R, Orlich M, Garrecht R, Hirtz M, Niemeyer C, Wu Y, Dehmelt L
ANGEW CHEM INT EDIT. 2017;56(21):5916-5920.

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Dahlke C, Kasonta R, Lunemann S, Krähling V, Zinser M, Biedenkopf N, Fehling S, Ly M, Rechtien A, Stubbe H, Olearo F, Borregaard S, Jambrecina A, Stahl F, Strecker T, Eickmann M, Lütgehetmann M, Spohn M, Schmiedel S, Lohse A, Becker S, Addo M
EBIOMEDICINE. 2017;19:107-118.

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice
Deppermann C, Kraft P, Volz J, Schuhmann M, Beck S, Wolf K, Stegner D, Stoll G, Nieswandt B
BLOOD. 2017;129(12):1702-1706.

Maternal progesterone levels are modulated by maternal BMI and predict birth weight sex-specifically in human pregnancies
Diemert A, Goletzke J, Barkmann C, Jung R, Hecher K, Arck P
J REPROD IMMUNOL. 2017;121:49-55.

The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis
Drube S, Grimlowski R, Deppermann C, Fröbel J, Kraft F, Andreas N, Stegner D, Dudeck J, Weber F, Rödiger M, Göpfert C, Drube J, Reich D, Nieswandt B, Dudeck A, Kamradt T
J IMMUNOL. 2017;199(8):2948-2957.

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions
Eken S, Jin H, Chernogubova E, Li Y, Simon N, Sun C, Korzunowicz G, Busch A, Bäcklund A, Österholm C, Razuvaev A, Renné T, Eckstein H, Pelisek J, Eriksson P, Gonzalez Diez M, Matic Perisic L, Schellinger I, Raaz U, Leeper N, Hansson G, Paulsson-Berne G, Hedin U, Maegdefessel L
CIRC RES. 2017;120(4):633-644.

High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression
Feuerborn R, Becker S, Potì F, Nagel P, Brodde M, Schmidt H, Christoffersen C, Ceglarek U, Burkhardt R, Nofer J
ATHEROSCLEROSIS. 2017;257:29-37.

First trimester TTR-RBP4-ROH complex and angiogenic factors in the prediction of small for gestational age infant's outcome
Fruscalzo A, Frommer J, Londero A, Henze A, Schweigert F, Nofer J, Steinhard J, Klockenbusch W, Schmitz R, Raila J
ARCH GYNECOL OBSTET. 2017;295(5):1157-1165.

MALDI mass spectrometry in medical research and diagnostic routine laboratories
Fuh M, Heikaus L, Schlüter H
INT J MASS SPECTROM. 2017;416(Special Issue ):96-109.

Protein Profile Analysis of Two Australian Snake Venoms by One- Dimensional Gel Electrophoresis and MS/MS Experiments
Georgieva D, Hildebrand D, Simas R, Coronado M, Kwiatkowski M, Schlüter H, Arni R, Spencer P, Betzel C
CURR MED CHEM. 2017;24(17):1892-1908.

Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins
Gleißner L, Kwiatkowski M, Myllynen L, Steffen P, Petersen C, Rothkamm K, Schlüter H, Kriegs M
ONCOTARGET. 2017;8(67):110983-110993.

Critical comments to a recent EFLM recommendation for the review of reference intervals
Haeckel R, Wosniok W, Arzideh F, Zierk J, Gurr E, Streichert T
CLIN CHEM LAB MED. 2017;55(3):341-347.

MALDI imaging mass spectrometry reveals multiple clinically relevant masses in colorectal cancer using large-scale tissue microarrays
Hinsch A, Buchholz M, Odinga S, Borkowski C, Koop C, Izbicki J, Wurlitzer M, Krech T, Wilczak W, Steurer S, Jacobsen F, Burandt E, Stahl P, Simon R, Sauter G, Schlüter H
J MASS SPECTROM. 2017;52(3):165-173.

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema
Hofman Z, de Maat S, Suffritti C, Zanichelli A, van Doorn C, Sebastian S, Veszeli N, Csuka D, Renné T, Pasterkamp G, Cicardi M, Farkas H, Hack C, Maas C
J ALLERGY CLIN IMMUN. 2017;140(6):1700-1703.e8.

Klüver-Bucy syndrome associated with a recessive variant in HGSNAT in two siblings with Mucopolysaccharidosis type IIIC (Sanfilippo C)
Hu H, Hübner C, Lukacs Z, Musante L, Gill E, Wienker T, Ropers H, Knierim E, Schuelke M
EUR J HUM GENET. 2017;25(2):253-256.

Reverse phase protein arrays enable glioblastoma molecular subtyping
Hutter G, Sailer M, Azad T, von Bueren A, Nollau P, Frank S, Tostado C, Sarvepalli D, Ghosh A, Ritz M, Boulay J, Mariani L
J NEURO-ONCOL. 2017;131(3):437-448.

Circulating Extracellular DNA: Cause or Consequence of Thrombosis?
Jiménez-Alcázar M, Kim N, Fuchs T
SEMIN THROMB HEMOST. 2017;43(6):553-561.

Host DNases prevent vascular occlusion by neutrophil extracellular traps
Jiménez-Alcázar M, Rangaswamy C, Panda R, Bitterling J, Simsek Y, Long A, Bilyy R, Krenn V, Renné C, Renné T, Kluge S, Panzer U, Mizuta R, Mannherz H, Kitamura D, Herrmann M, Napirei M, Fuchs T
SCIENCE. 2017;358(6367):1202-1206.

A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran
Keyfi F, Lukacs Z, Varasteh A
REP BIOCHEM MOL BIOL. 2017;6(1):40-50.

Identification of novel parasitophorous vacuole proteins in P. falciparum parasites using BioID
Khosh-Naucke M, Becker J, Mesén-Ramírez P, Kiani P, Birnbaum J, Fröhlke U, Jonscher E, Schlüter H, Spielmann T
INT J MED MICROBIOL. 2017 [Epub ahead of print];308:13-24.

A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury
Kleinschmidt D, Giannou A, McGee H, Kempski J, Steglich B, Huber F, Ernst T, Shiri A, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse A, Axelrod J, Galun E, Flavell R, Gagliani N, Huber S
J IMMUNOL. 2017;199(12):4078-4090.

Host Cell Proteins in Biologics Manufacturing: The Good, the Bad, and the Ugly
Kornecki M, Mestmäcker F, Zobel-Roos S, Heikaus L, Schlüter H, Strube J
ANTIBODIES. 2017;6(3):13.

Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach S, Walter U, Ruggeri Z, Renné T, Ruf W, Münzel T, Wenzel P
SCI TRANSL MED. 2017;9(375):.

Consensus recommendation for a diagnostic guideline for acid sphingomyelinase deficiency
McGovern M, Dionisi-Vici C, Giugliani R, Hwu P, Lidove O, Lukacs Z, Eugen Mengel K, Mistry P, Schuchman E, Wasserstein M
GENET MED. 2017;19(9):967-974.

Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats
Miller K, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D
TRANSPL INT. 2017;30(11):1181-1189.

Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum
Müller C, Gehlen D, Blaich C, Prozeller D, Liss B, Streichert T, Wiesen M
THER DRUG MONIT. 2017;39(5):505-513.

Missing in action-The meaning of cell death in tissue damage and inflammation
Muñoz L, Leppkes M, Fuchs T, Hoffmann M, Herrmann M
IMMUNOL REV. 2017;280(1):26-40.

Factor XII Contact Activation
Naudin C, Burillo E, Blankenberg S, Butler L, Renné T
SEMIN THROMB HEMOST. 2017;43(8):814-826.

Early diagnosis of acute myocardial infarction using high-sensitivity troponin I
Neumann J, Sörensen N, Ojeda F, Renné T, Schnabel R, Zeller T, Karakas M, Blankenberg S, Westermann D
PLOS ONE. 2017;12(3):e0174288.

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I
Neumann J, Sörensen N, Ojeda F, Schwemer T, Lehmacher J, Gönner S, Jarsetz N, Keller T, Schaefer S, Renné T, Landmesser U, Clemmensen P, Makarova N, Schnabel R, Zeller T, Karakas M, Pickering J, Than M, Parsonage W, Greenslade J, Cullen L, Westermann D, Blankenberg S
CLIN CHEM. 2017;63(1):394-402.

Discrimination of patients with type 2 myocardial infarction
Neumann J, Sörensen N, Rübsamen N, Ojeda F, Renné T, Qaderi V, Teltrop E, Kramer S, Quantius L, Zeller T, Karakas M, Blankenberg S, Westermann D
EUR HEART J. 2017;38(47):3514-3520.

Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases
Nickel K, Long A, Fuchs T, Butler L, Renné T
ARTERIOSCL THROM VAS. 2017;37(1):13-20.

A qualitative comparison of ten tissue clearing techniques
Orlich M
HISTOL HISTOPATHOL. 2017;2018(33):181-199.

Low-dose fixed-target serial synchrotron crystallography
Owen R, Axford D, Sherrell D, Kuo A, Ernst O, Schulz E, Miller R, Mueller-Werkmeister H
ACTA CRYSTALLOGR D. 2017;73(Pt 4):373-378.

Neutrophil Extracellular Traps Contain Selected Antigens of Anti-Neutrophil Cytoplasmic Antibodies
Panda R, Krieger T, Hopf L, Renné T, Haag F, Röber N, Conrad K, Csernok E, Fuchs T
FRONT IMMUNOL. 2017;8:439.

Occurrence of Spirocerca lupi Infection in Hungarian Dogs Referred for Gastroscopy
Psáder R, Balogh M, Pápa K, Sterczer Á, Lukács Z, Harnos A
PARASITOL RES. 2017;116(Suppl 1):99-108.

Abstracts of papers presented at the 1st Italian-UK Platelet Meeting University of Bath, 7-8 September 2017
Pula G, Canobbio I, Torti M
PLATELETS. 2017 [Epub ahead of print];1-27.

Neues vom Faktor XII
Renne T
Trillium Diagnostik. 2017;15(4):252-255.

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
Rösch K, Kwiatkowski M, Schlüter H, Herker E
JOVE-J VIS EXP. 2017;(122):.

CD4+ T cells from patients with primary sclerosing cholangitis exhibit reduced apoptosis and down-regulation of proapoptotic Bim in peripheral blood
Schoknecht T, Schwinge D, Stein S, Weiler-Normann C, Sebode M, Mucha S, Otto B, Ellinghaus E, Stahl F, Franke A, Lohse A, Herkel J, Schramm C
J LEUKOCYTE BIOL. 2017;101(2):589-597.

Challenging the 99th percentile: A lower troponin cutoff leads to low mortality of chest pain patients
Sörensen N, Neumann J, Ojeda F, Schwemer T, Renné T, Schnabel R, Zeller T, Karakas M, Blankenberg S, Westermann D
INT J CARDIOL. 2017;232:289-293.

Targeting transcription factor lysine acetylation in inflammatory airway diseases
van den Bosch T, Kwiatkowski M, Bischoff R, Dekker F
EPIGENOMICS-UK. 2017;9(7):1013-1028.

Polyphosphate nanoparticles on the platelet surface trigger contact system activation
Verhoef J, Barendrecht A, Nickel K, Dijkxhoorn K, Kenne E, Labberton L, McCarty O, Schiffelers R, Heijnen H, Hendrickx A, Schellekens H, Fens M, de Maat S, Renné T, Maas C
BLOOD. 2017;129(12):1707-1717.

The plasma contact system, a protease cascade at the nexus of inflammation, coagulation and immunity
Weidmann H, Heikaus L, Long A, Naudin C, Schlüter H, Renné T
BBA-MOL CELL RES. 2017;1864(11 Pt B):2118-2127.

Paramagnetic micro-particles as a tool for rapid quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma by UHPLC-MS/MS
Wiesen M, Blaich C, Streichert T, Michels G, Müller C
CLIN CHEM LAB MED. 2017;55(9):1349-1359.

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Agnandji S, Huttner A, Zinser M, Njuguna P, Dahlke C, Fernandes J, Yerly S, Dayer J, Kraehling V, Kasonta R, Adegnika A, Altfeld M, Auderset F, Bache E, Biedenkopf N, Borregaard S, Brosnahan J, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling S, Finckh A, Goncalves A, Grobusch M, Hooper J, Jambrecina A, Kabwende A, Kaya G, Kimani D, Lell B, Lemaître B, Lohse A, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl F, Staines H, Strecker T, Stubbe H, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny M, Bejon P, Kremsner P, Addo M, Siegrist C
NEW ENGL J MED. 2016;374(17):1647-60.

Motor Performance Is not Enhanced by Daytime Naps in Older Adults
Backhaus W, Braass H, Renné T, Gerloff C, Hummel F
FRONT AGING NEUROSCI. 2016;8:125.

Daytime sleep has no effect on the time course of motor sequence and visuomotor adaptation learning
Backhaus W, Braaß H, Renné T, Krüger C, Gerloff C, Hummel F
NEUROBIOL LEARN MEM. 2016;131:147-54.

Catalytic Subunit 1 of Protein Phosphatase 2A Is a Subunit of the STRIPAK Complex and Governs Fungal Sexual Development
Beier A, Teichert I, Krisp C, Wolters D, Kück U
MBIO. 2016;7(3):.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney A, Nolte F, Buck F, Perbandt M, Betzel C, Svergun D, Hentschke M, Aepfelbacher M
PLOS PATHOG. 2016;12(6):e1005660.

Modulation of Thrombosis Significantly Reduces Testicular Damage after Testicular Torsion in Rats: Anti-Thrombotic Treatment and Testicular Torsion
Boettcher M, Fuchs T, Schäfer H, Appl B, Trochimiuk M, Jiménez-Alcázar M, Tiemann B, Jung R, Bergholz R, Reinshagen K, Eschenburg G
UROLOGY. 2016;88(227):e1-7.

A standardised FACS assay based on native, receptor transfected cells for the clinical diagnosis and monitoring of β1-adrenergic receptor autoantibodies in human heart disease
Bornholz B, Benninghaus T, Reinke Y, Felix S, Roggenbuck D, Jahns-Boivin V, Jahns R, Boege F
CLIN CHEM LAB MED. 2016;54(4):683-91.

PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study
Bruzelius M, Iglesias M, Hong M, Sanchez-Rivera L, Gyorgy B, Souto J, Frånberg M, Fredolini C, Strawbridge R, Holmström M, Hamsten A, Uhlén M, Silveira A, Soria J, Smadja D, Butler L, Schwenk J, Morange P, Trégouët D, Odeberg J
BLOOD. 2016;128(23):e59-e66.

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome
Butler L, Hallström B, Fagerberg L, Pontén F, Uhlén M, Renné T, Odeberg J
CELL SYST. 2016;3(3):287-301.e3.

Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations
de Maat S, Björkqvist J, Suffritti C, Wiesenekker C, Nagtegaal W, Koekman A, van Dooremalen S, Pasterkamp G, de Groot P, Cicardi M, Renné T, Maas C
J ALLERGY CLIN IMMUN. 2016;138(5):1414-1423.e9.

Platelets and infection
Deppermann C, Kubes P
SEMIN IMMUNOL. 2016;28(6):536-545.

The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation
Deuse T, Hua X, Stubbendorff M, Spin J, Neofytou E, Taylor V, Chen Y, Park G, Fink J, Renne T, Kiefmann M, Kiefmann R, Reichenspurner H, Robbins R, Schrepfer S
TRANSPLANTATION. 2016;100(5):1022-1031.

Diagnosis of neuronal ceroid lipofuscinosis type 2 (CLN2 disease): Expert recommendations for early detection and laboratory diagnosis
Fietz M, AlSayed M, Burke D, Cohen-Pfeffer J, Cooper J, Dvořáková L, Giugliani R, Izzo E, Jahnová H, Lukacs Z, Mole S, Noher de Halac I, Pearce D, Poupetova H, Schulz A, Specchio N, Xin W, Miller N
MOL GENET METAB. 2016;119(1-2):160-7.

Tools for the analysis and characterization of therapeutic protein species
Fuh M, Steffen P, Schlüter H
Biosimilars. 2016;6:17-24.

The Prevalence of Sickle Cell Disease and Its Implication for Newborn Screening in Germany (Hamburg Metropolitan Area)
Grosse R, Lukacs Z, Cobos P, Oyen F, Ehmen C, Muntau B, Timmann C, Noack B
PEDIATR BLOOD CANCER. 2016;63(1):168-70.

Improvement of neuronal cell survival by astrocyte-derived exosomes under hypoxic and ischemic conditions depends on prion protein
Guitart K, Loers G, Buck F, Bork U, Schachner M, Kleene R
GLIA. 2016;64(6):896-910.

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity
Halle S, Keyser K, Stahl F, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovskii A, Kempf H, Meyer-Hermann M, Arens R, Kremer M, Sutter G, Messerle M, Förster R
IMMUNITY. 2016;44(2):233-45.

Parathyroid hormone induces expression and proteolytic processing of Rankl in primary murine osteoblasts
Heckt T, Keller J, Peters S, Streichert T, Chalaris A, Rose-John S, Mell B, Joe B, Amling M, Schinke T
BONE. 2016;92:85-93.

Congenital Adrenal Hyperplasia with Non-functional Mutations in Both Alleles in a Clinically Unaffected Infant
Hoehn T, Lukacs Z, Huckenbeck W, Torresani T, Blankenstein O, Bounnack S
J TROP PEDIATRICS. 2016;62(2):158-60.

Internal standardization of LA-ICP-MS immuno imaging via printing of universal metal spiked inks onto tissue sections
Hoesl S, Neumann B, Techritz S, Sauter G, Simon R, Schlüter H, Linscheid M, Theuring F, Jakubowski N, Mueller L
J ANAL ATOM SPECTROM. 2016;31(3):801-808.

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue
Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt M, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A
PLOS ONE. 2016;11(2):e0145937.

Intramedullary Mg2Ag nails augment callus formation during fracture healing in mice
Jähn K, Saito H, Taipaleenmäki H, Gasser A, Hort N, Feyerabend F, Schlüter H, Rueger J, Lehmann W, Willumeit-Römer R, Hesse E
ACTA BIOMATER. 2016;36:350-60.

Towards deciphering proteomes via the proteoform, protein speciation, moonlighting and protein code concepts
Jungblut P, Thiede B, Schlüter H
J PROTEOMICS. 2016;134:1-4.

A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation
Kokoye Y, Ivanov I, Cheng Q, Matafonov A, Dickeson S, Mason S, Sexton D, Renné T, McCrae K, Feener E, Gailani D
THROMB RES. 2016;140:118-124.

Homogenization of tissues via picosecond-infrared laser (PIRL) ablation: Giving a closer view on the in-vivo composition of protein species as compared to mechanical homogenization
Kwiatkowski M, Wurlitzer M, Krutilin A, Kiani P, Nimer R, Omidi M, Mannaa A, Bussmann T, Bartkowiak K, Kruber S, Uschold S, Steffen P, Lübberstedt J, Küpker N, Petersen H, Knecht R, Hansen N, Zarrine-Afsar A, Robertson W, Miller R, Schlüter H
J PROTEOMICS. 2016;134:193-202.

Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection
Labberton L, Kenne E, Long A, Nickel K, Di Gennaro A, Rigg R, Hernandez J, Butler L, Maas C, Stavrou E, Renné T
NAT COMMUN. 2016;7:12616.

Contact system revisited: an interface between inflammation, coagulation, and innate immunity
Long A, Kenne E, Jung R, Fuchs T, Renné T
J THROMB HAEMOST. 2016;14(3):427-37.

Prevalence of Pompe disease in 3,076 patients with hyperCKemia and limb-girdle muscular weakness
Lukacs Z, Nieves Cobos P, Wenninger S, Willis T, Guglieri M, Roberts M, Quinlivan R, Hilton-Jones D, Evangelista T, Zierz S, Schlotter-Weigel B, Walter M, Reilich P, Klopstock T, Deschauer M, Straub V, Müller-Felber W, Schoser B
NEUROLOGY. 2016;87(3):295-8.

Erratum to: Vegfr3-CreERmouse, a new genetic tool for targeting the lymphatic system
Martinez-Corral I, Stanczuk L, Frye M, Ulvmar M, Diéguez-Hurtado R, Olmeda D, Makinen T, Ortega S
ANGIOGENESIS. 2016;19(3):447.

Vegfr3-CreER (T2) mouse, a new genetic tool for targeting the lymphatic system
Martinez-Corral I, Stanczuk L, Frye M, Ulvmar M, Diéguez-Hurtado R, Olmeda D, Makinen T, Ortega S
ANGIOGENESIS. 2016;19(3):433-45.

Urticaria as a Presenting Prodromal Manifestation of Attacks of Hereditary Angioedema
Martin L, Renné T, Drouet C
ACTA DERM-VENEREOL. 2016;96(4):574-5.

Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour Algorithm
Neumann J, Sörensen N, Schwemer T, Ojeda F, Bourry R, Sciacca V, Schaefer S, Waldeyer C, Sinning C, Renné T, Than M, Parsonage W, Wildi K, Makarova N, Schnabel R, Landmesser U, Mueller C, Cullen L, Greenslade J, Zeller T, Blankenberg S, Karakas M, Westermann D
JAMA CARDIOL. 2016;1(4):397-404.

The polyphosphate/factor XII pathway in cancer-associated thrombosis: novel perspectives for safe anticoagulation in patients with malignancies
Nickel K, Labberton L, Long A, Langer F, Fuchs T, Stavrou E, Butler L, Renné T
THROMB RES. 2016;141 Suppl 2:S4-7.

Comparative study of wound healing in rat skin following incision with a novel picosecond infrared laser (PIRL) and different surgical modalities
Petersen H, Tavakoli F, Kruber S, Münscher A, Gliese A, Hansen N, Uschold S, Eggert D, Robertson W, Gosau T, Sehner S, Kwiatkowski M, Schlüter H, Schumacher U, Knecht R, Miller R
LASER SURG MED. 2016;48(4):385-91.

Quantitative Lipid Droplet Proteome Analysis Identifies Annexin A3 as a Cofactor for HCV Particle Production
Rösch K, Kwiatkowski M, Hofmann S, Schöbel A, Grüttner C, Wurlitzer M, Schlüter H, Herker E
CELL REP. 2016;16(12):3219-31.

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure
Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker P, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F
FASEB J. 2016;30(5):1849-64.

Protein species as diagnostic markers
Steffen P, Kwiatkowski M, Robertson W, Zarrine-Afsar A, Deterra D, Richter V, Schlüter H
J PROTEOMICS. 2016;134:5-18.

Structure and target interaction of a G-quadruplex RNA-aptamer
Szameit K, Berg K, Kruspe S, Valentini E, Magbanua E, Kwiatkowski M, Chauvot de Beauchêne I, Krichel B, Schamoni K, Uetrecht C, Svergun D, Schlüter H, Zacharias M, Hahn U
DEV BIOL. 2016;13(10):973-987.

Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects
Tillner J, Lehmann A, Paehler T, Lukacs Z, Ruf S, Sadowski T, Pinquier J, Ruetten H
CLIN PHARM DRUG DEV. 2016;5(1):57-68.

Björn J. Öbrink (1943-2015)
Wagener C, Singer B
EXP CELL RES. 2016;341(1):75-6.

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, Logsdon M, Brandner J, Tiegs G, Beauchemin N, Wagener C, Deppert W, Horst A
ONCOTARGET. 2016;7(39):63730-63746.

Immediate effects of retinoic acid on gene expression in primary murine osteoblasts
Yorgan T, Heckt T, Rendenbach C, Helmis C, Seitz S, Streichert T, Amling M, Schinke T
J BONE MINER METAB. 2016;34(2):161-70.

The Alzheimer's disease peptide Aβ promotes thrombin generation through activation of coagulation factor XII
Zamolodchikov D, Renné T, Strickland S
J THROMB HAEMOST. 2016;14(5):995-1007.

Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity
Abramowski P, Kraus O, Rohn S, Riecken K, Fehse B, Schlüter H
CANCER GENOM PROTEOM. 2015;12(4):179-187.

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression
Anderson H, Patch T, Reddy P, Hagedorn E, Kim P, Soltis K, Chen M, Tamplin O, Frye M, MacLean G, Hübner K, Bauer D, Kanki J, Vogin G, Huston N, Nguyen M, Fujiwara Y, Paw B, Vestweber D, Zon L, Orkin S, Daley G, Shah D
BLOOD. 2015;126(26):2811-20.

Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak K, Kwiatkowski M, Buck F, Gorges T, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K
CANCER RES. 2015;75(24):5367-77.

Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
Björkqvist J, de Maat S, Lewandrowski U, Di Gennaro A, Oschatz C, Schönig K, Nöthen M, Drouet C, Braley H, Nolte M, Sickmann A, Panousis C, Maas C, Renné T
J CLIN INVEST. 2015;125(8):3132-46.

Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria
Brandt S, Krauel K, Jaax M, Renné T, Helm C, Hammerschmidt S, Delcea M, Greinacher A
THROMB HAEMOSTASIS. 2015;114(6):1189-98.

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN
Brix S, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira S, Tacke F, Wolf G, Busch M, Jabs W, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl R
J AM SOC NEPHROL. 2015;26(9):2105-2117.

Tissue factor-dependent and -independent pathways of systemic coagulation activation in acute myeloid leukemia: a single-center cohort study
Dicke C, Amirkhosravi A, Spath B, Jiménez-Alcázar M, Fuchs T, Davila M, Francis J, Bokemeyer C, Langer F
EXP HEMATOL ONCOL. 2015;4:22.

Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic Syndrome: a case-control study
Doulgere J, Otto B, Nassour M, Wolters-Eisfeld G, Rohde H, Magnus T, Wagener C, Streichert T
BMJ OPEN. 2015;5(3):e005659.

Isolation, identification and functional profile of excretory-secretory peptides from Onchocerca ochengi
Eberle R, Brattig N, Trusch M, Schlüter H, Achukwi M, Eisenbarth A, Renz A, Liebau E, Perbandt M, Betzel C
ACTA TROP. 2015;142:156-66.

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin
Frye M, Dierkes M, Küppers V, Vockel M, Tomm J, Zeuschner D, Rossaint J, Zarbock A, Koh G, Peters K, Nottebaum A, Vestweber D
J EXP MED. 2015;212(13):2267-87.

Direct infection of primary endothelial cells with human cytomegalovirus prevents angiogenesis and migration
Gustafsson R, Jeffery H, Yaiw K, Wilhelmi V, Kostopoulou O, Davoudi B, Rahbar A, Benard M, Renné T, Söderberg-Nauclér C, Butler L
J GEN VIROL. 2015;96(12):3598-3612.

Dried Blood Spot for Screening for Late-Onset Pompe Disease: A Spanish Cohort
Gutiérrez-Rivas E, Bautista J, Vílchez J, Muelas N, Díaz-Manera J, Illa I, Martínez-Arroyo A, Olivé M, Sanz I, Arpa J, Fernández-Torrón R, López de Munáin A, Jiménez L, Solera J, Lukacs Z
J NEUROMUSCULAR DIS. 2015;2(s1):S42.

Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: A Spanish cohort
Gutiérrez-Rivas E, Bautista J, Vílchez J, Muelas N, Díaz-Manera J, Illa I, Martínez-Arroyo A, Olivé M, Sanz I, Arpa J, Fernández-Torrón R, López de Munáin A, Jiménez L, Solera J, Lukacs Z
NEUROMUSCULAR DISORD. 2015;25(7):548-53.

Identification and analysis of ADP-ribosylated proteins
Haag F, Buck F
CURR TOP MICROBIOL. 2015;384:33-50.

COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer
Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak A, Harder S, El Gammal A, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki J, Jücker M, Bockhorn M, Wolters-Eisfeld G
MOL CANCER. 2015;14(1):109.

Activation of Cell Surface Bound 20S Proteasome Inhibits Vascular Cell Growth and Arteriogenesis
Ito W, Lund N, Zhang Z, Buck F, Lellek H, Horst A, Machens H, Schunkert H, Schaper W, Meinertz T
BIOMED RES INT . 2015;2015:719316.

Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells
Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
J IMMUNOL. 2015;195(8):3675-84.

Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies
Jiménez-Alcázar M, Napirei M, Panda R, Köhler E, Kremer Hovinga J, Mannherz H, Peine S, Renné T, Lämmle B, Fuchs T
J THROMB HAEMOST. 2015;13(5):732-42.

Factor XII: a novel target for safe prevention of thrombosis and inflammation
Kenne E, Nickel K, Long A, Fuchs T, Stavrou E, Stahl F, Renné T
J INTERN MED. 2015;278(6):571-85.

Calcium gluconate supplementation is effective to balance calcium homeostasis in patients with gastrectomy
Krause M, Keller J, Beil B, van Driel I, Zustin J, Barvencik F, Schinke T, Amling M
OSTEOPOROSIS INT. 2015;26(3):987-95.

Online Peptide fractionation using a multiphasic microfluidic liquid chromatography chip improves reproducibility and detection limits for quantitation in discovery and targeted proteomics
Krisp C, Yang H, van Soest R, Molloy M
MOL CELL PROTEOMICS. 2015;14(6):1708-19.

Ultrafast extraction of proteins from tissues using desorption by impulsive vibrational excitation
Kwiatkowski M, Wurlitzer M, Omidi M, Ren L, Kruber S, Nimer R, Robertson W, Horst A, Miller R, Schlüter H
ANGEW CHEM INT EDIT. 2015;54(1):285-8.

New agents for thromboprotection. A role for factor XII and XIIa inhibition
Labberton L, Kenne E, Renné T
HAMOSTASEOLOGIE. 2015;35(4):338-50.

Thrombin generation test in children and adolescents with chronic liver disease
Magnusson M, Berndtsson M, Fischler B, Petrini P, Schulman S, Renne T, Granath A, Sten-Linder M, Németh A
THROMB RES. 2015;135(2):382-7.

Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration
Meka P, Müller-Rischart A, Nidadavolu P, Mohammadi B, Motori E, Ponna S, Aboutalebi H, Bassal M, Annamneedi A, Finckh B, Miesbauer M, Rotermund N, Lohr C, Tatzelt J, Winklhofer K, Kramer E
J CLIN INVEST. 2015;125(5):1873-85.

Homozygosity for the common GAA gene splice site mutation c.-32-13T>G in Pompe disease is associated with the classical adult phenotypical spectrum
Musumeci O, Thieme A, Claeys K, Wenninger S, Kley R, Kuhn M, Lukacs Z, Deschauer M, Gaeta M, Toscano A, Gläser D, Schoser B
NEUROMUSCULAR DISORD. 2015;25(9):719-24.

Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1
Myllynen L, Kwiatkowski M, Gleißner L, Riepen B, Hoffer K, Wurlitzer M, Petersen C, Dikomey E, Rothkamm K, Schlüter H, Kriegs M
RADIOTHER ONCOL. 2015;116(3):423-30.

The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis
Nickel K, Ronquist G, Langer F, Labberton L, Fuchs T, Bokemeyer C, Sauter G, Graefen M, Mackman N, Stavrou E, Ronquist G, Renné T
BLOOD. 2015;126(11):1379-89.

The vascular side of plasma kallikrein
Renné T
BLOOD. 2015;125(4):589-90.

Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions
Sala-Cunill A, Björkqvist J, Senter R, Guilarte M, Cardona V, Labrador M, Nickel K, Butler L, Luengo O, Kumar P, Labberton L, Long A, Di Gennaro A, Kenne E, Jämsä A, Krieger T, Schlüter H, Fuchs T, Flohr S, Hassiepen U, Cumin F, McCrae K, Maas C, Stavrou E, Renné T
J ALLERGY CLIN IMMUN. 2015;135(4):1031-1043.e6.

Thrombin generation in a patient with an acquired high-titre factor V inhibitor
Schmidt D, Steinhagen F, Schnabel C, Spath B, Holstein K, Fiedler W, Bokemeyer C, Renné T, Langer F
BLOOD COAGUL FIBRIN. 2015;26(1):81-87.

The Plasmodium falciparum exportome contains non-canonical PEXEL/HT proteins
Schulze J, Kwiatkowski M, Borner J, Schlüter H, Bruchhaus I, Burmester T, Spielmann T, Pick C
MOL MICROBIOL. 2015;97(2):301-314.

First report of a FXII gene mutation in a Brazilian family with hereditary angioedema with normal C1 inhibitor
Stieber C, Grumach A, Cordeiro E, Constantino-Silva R, Barth S, Hoffmann P, Renné T, Nöthen M, Cichon S
BRIT J DERMATOL. 2015;173(4):1102-1104.

Tuning IL-2 signaling by ADP-ribosylation of CD25
Teege S, Hann A, Miksiewicz M, MacMillan C, Rissiek B, Buck F, Menzel S, Nissen M, Bannas P, Haag F, Boyer O, Seman M, Adriouch S, Nolte F
SCI REP-UK. 2015;10(5):8959.

Prenatal Acetaminophen Affects Maternal Immune and Endocrine Adaptation to Pregnancy, Induces Placental Damage, and Impairs Fetal Development in Mice
Thiele K, Solano M, Huber S, Flavell R, Kessler T, Barikbin R, Jung R, Karimi K, Tiegs G, Arck P
AM J PATHOL. 2015;185(10):2805-2818.

The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation
Thottakara T, Friedrich F, Reischmann S, Braumann S, Schlossarek S, Krämer E, Juhr D, Schlüter H, van der Velden J, Münch J, Patten M, Eschenhagen T, Moog-Lutz C, Carrier L
J MOL CELL CARDIOL. 2015;87:214-224.

Evaluating the Hypoxia Response of Ruffe and Flounder Gills by a Combined Proteome and Transcriptome Approach
Tiedke J, Borner J, Beeck H, Kwiatkowski M, Schmidt H, Thiel R, Fabrizius A, Burmester T
PLOS ONE. 2015;10(8):e0135911.

Proteomic analysis of the rare Uracoan rattlesnake Crotalus vegrandis venom: Evidence of a broad arsenal of toxins
Viala V, Hildebrand D, Fucase T, Sciani J, Prezotto-Neto J, Riedner M, Sanches L, Nishimura P, Oguiura N, Pimenta D, Schlüter H, Betzel C, Arni R, Spencer P
TOXICON. 2015;107(Pt B):234-51.

Venomics of the Australian eastern brown snake (Pseudonaja textilis): Detection of new venom proteins and splicing variants
Viala V, Hildebrand D, Trusch M, Fucase T, Sciani J, Pimenta D, Arni R, Schlüter H, Betzel C, Mirtschin P, Dunstan N, Spencer P
TOXICON. 2015;107(Pt B):252-65.

Hospital population screening reveals overrepresentation of CD5(-) monoclonal B-cell lymphocytosis and monoclonal gammopathy of undetermined significance of IgM type
Voigtländer M, Vogler B, Trepel M, Panse J, Jung R, Bokemeyer C, Bacher U, Binder M
ANN HEMATOL. 2015;94(9):1559-65.

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret A, Kemming D, Wood A, Edgren H, Neubauer H, Streichert T, Riethdorf S, Bedi U, Baccelli I, Jücker M, Eils R, Fehm T, Trumpp A, Johnsen S, Klefstrom J, Wilmanns M, Müller V, Pantel K, Wikman-Kocher H
CANCER DISCOV. 2015;5(5):506-19.

The factor XIIa blocking antibody 3F7: a safe anticoagulant with anti-inflammatory activities
Worm M, Köhler E, Panda R, Long A, Butler L, Stavrou E, Nickel K, Fuchs T, Renné T
J TRANSL MED. 2015;3(17):247.

Integrin β1 controls VE-cadherin localization and blood vessel stability
Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams R
NAT COMMUN. 2015;6:6429.

Activation of the factor XII-driven contact system in Alzheimer's disease patient and mouse model plasma
Zamolodchikov D, Chen Z, Conti B, Renné T, Strickland S
P NATL ACAD SCI USA. 2015;112(13):4068-73.

The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response
Abramowski P, Otto B, Martin R
PLOS ONE. 2014;9(3):e91970.

Preliminary crystallographic analysis of a cruciferin protein from seeds of Moringa oleifera
Akrem A, Yousef N, Begum A, Negm A, Meyer A, Perbandt M, Buck F, Betzel C
PROTEIN J. 2014;33(3):253-7.

PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium
Anton K, Sinclair J, Ohoka A, Kajita M, Ishikawa S, Benz P, Renne T, Balda M, Jorgensen C, Matter K, Fujita Y
J CELL SCI. 2014;127(16):3425-33.

Subcellular sorting of the G-protein coupled mouse somatostatin receptor 5 by a network of PDZ-domain containing proteins
Bauch C, Koliwer J, Buck F, Hönck H, Kreienkamp H
PLOS ONE. 2014;9(2):e88529.

Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways
Beck F, Geiger J, Gambaryan S, Veit J, Vaudel M, Nollau P, Kohlbacher O, Martens L, Walter U, Sickmann A, Zahedi R
BLOOD. 2014;123(5):e1-e10.

Alterations in the Ubiquitin Proteasome System in Persistent but Not Reversible Proteinuric Diseases
Beeken M, Lindenmeyer M, Blattner S, Radón V, Oh J, Meyer T, Hildebrand D, Schlüter H, Reinicke-Vogt A, Knop J, Vivekanandan-Giri A, Münster S, Sachs M, Wiech T, Pennathur S, Cohen C, Kretzler M, Stahl R, Meyer-Schwesinger C
J AM SOC NEPHROL. 2014;25(11):2511-25.

In vivo activation and functions of the protease factor XII
Björkqvist J, Nickel K, Stavrou E, Renne T
THROMB HAEMOSTASIS. 2014;112(5):868-875.

Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity
Brandt S, Krauel K, Gottschalk K, Renné T, Helm C, Greinacher A, Block S
THROMB HAEMOSTASIS. 2014;112(1):.

Ambient-und Biomonitoring nach Quecksilberintoxikation
Budnik L, Hermann K, Preisser A, Nordholt G, Harth V, Mühlhausen C
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Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli
Christner M, Trusch M, Rohde H, Kwiatkowski M, Schlüter H, Wolters M, Aepfelbacher M, Hentschke M
PLOS ONE. 2014;9(7):e101924.

Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group
Cicardi M, Aberer W, Banerji A, Bas M, Bernstein J, Bork K, Caballero T, Farkas H, Grumach A, Kaplan A, Riedl M, Triggiani M, Zanichelli A, Zuraw B
ALLERGY. 2014;69(5):602-16.

Dried Blood Spots Allow Targeted Screening to Diagnose Mucopolysaccharidosis and Mucolipidosis
Cobos P, Steglich C, Santer R, Lukacs Z, Gal A
JIMD reports. 2014.

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease
Dohler F, Sepulveda-Falla D, Krasemann S, Altmeppen H, Schlüter H, Hildebrand D, Zerr I, Matschke J, Glatzel M
BRAIN. 2014;137(Pt 3):873-86.

A non-canonical initiation site is required for efficient translation of the dendritically localized Shank1 mRNA
Falley K, Ölschläger-Schütt J, Buck F, Richter D, Sala C, Bockmann J, Kindler S, Kreienkamp H
PLOS ONE. 2014;9(2):e88518.

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia
Frietsch J, Kastner C, Grunewald T, Schweigel H, Nollau P, Ziermann J, Clement J, La Rosée P, Hochhaus A, Butt E
ONCOTARGET. 2014;5(14):5257-71.

Alpha-1-antitrypsin: A Novel Human High Temperature Requirement Protease A1 (HTRA1) Substrate in Human Placental Tissue
Frochaux V, Hildebrand D, Talke A, Linscheid M, Schlüter H
PLOS ONE. 2014;9(10):e109483.

Carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1, 5 and 6 as biomarkers in pancreatic cancer
Gebauer F, Wicklein D, Horst J, Sundermann P, Maar H, Streichert T, Tachezy M, Izbicki J, Bockhorn M, Schumacher U
PLOS ONE. 2014;9(11):e113023.

Multicenter method evaluation of the ARK™ Methotrexate Immunoassay
Godefroid M, von Meyer A, Parsch H, Streichert T, Verstraete A, Stove V
CLIN CHEM LAB MED. 2014;52(2):e13-6.

High-frequency stimulation of the subthalamic nucleus counteracts cortical expression of major histocompatibility complex genes in a rat model of Parkinson's disease
Grieb B, Engler G, Sharott A, von Nicolai C, Streichert T, Papageorgiou I, Schulte A, Westphal M, Lamszus K, Engel A, Moll C, Hamel W
PLOS ONE. 2014;9(3):e91663.

Increased Osteoclastogenesis in Mice Lacking the Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
Heckt T, Bickert T, Jeschke A, Seitz S, Schulze J, Ito W, Zimmermann W, Amling M, Schinke T, Horst A, Keller J
PLOS ONE. 2014;9(12):e114360.

ABO blood group IgM isoagglutinins interact with tumor-associated O-glycan structures in pancreatic cancer
Hofmann B, Stehr A, Dohrmann T, Güngör C, Herich L, Hiller J, Harder S, Ewald F, Gebauer F, Tachezy M, Precht C, Izbicki J, Bockhorn M, Wagener C, Wolters-Eisfeld G
CLIN CANCER RES. 2014;20(23):6117-26.

Proteome analysis of the effects of all-trans retinoic acid on human germ cell tumor cell lines
Honecker F, Rohlfing T, Harder S, Braig M, Gillis A, Gläsener S, Barett C, Bokemeyer C, Buck F, Brümmendorf T, Looijenga L, Balabanov S
J PROTEOMICS. 2014;96:300-13.

CEA a thrombus CAM: CEACAM2, a twin of CEACAM1?
Horst A
BLOOD. 2014;124(15):2323-4.

Interaction of the Cell Adhesion Molecule CHL1 with Vitronectin, Integrins, and the Plasminogen Activator Inhibitor-2 Promotes CHL1-Induced Neurite Outgrowth and Neuronal Migration
Katic J, Loers G, Kleene R, Karl N, Schmidt C, Buck F, Zmijewski J, Jakovcevski I, Preissner K, Schachner M
J NEUROSCI. 2014;34(44):14606-23.

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
Keller J, Catala-Lehnen P, Hübner A, Jeschke A, Heckt T, Lueth A, Krause M, Koehne T, Albers J, Schulze J, Schilling S, Haberland M, Denninger H, Neven M, Hermans-Borgmeyer I, Streichert T, Breer S, Barvencik F, Levkau B, Rathkolb B, Wolf E, Calzada-Wack J, Neff F, Gailus-Durner V, Fuchs H, de Angelis M, Klutmann S, Tsourdi E, Hofbauer L, Kleuser B, Chun J, Schinke T, Amling M
NAT COMMUN. 2014;5:5215.

Factor XII - a drug target for safe interference with thrombosis and inflammation
Kenne E, Renné T
DRUG DISCOV TODAY. 2014;19(9):1459-64.

Sample displacement batch chromatography of proteins
Kotasinska M, Richter V, Kwiatkowski M, Schlüter H
Methods Mol Biol. 2014;1129:325-38.

A case of severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse A, Addo M, Schmiedel S
NEW ENGL J MED. 2014;371(25):2394-401.

Factor XII Regulates the Pathological Process of Thrombus Formation on Ruptured Plaques
Kuijpers M, van der Meijden P, Feijge M, Mattheij N, May F, Govers-Riemslag J, Meijers J, Heemskerk J, Renné T, Cosemans J
ARTERIOSCL THROM VAS. 2014;34(8):1674-80.

A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk
Larsson M, Rayzman V, Nolte M, Nickel K, Björkqvist J, Jämsä A, Hardy M, Fries M, Schmidbauer S, Hedenqvist P, Broomé M, Pragst I, Dickneite G, Wilson M, Nash A, Panousis C, Renné T
SCI TRANSL MED. 2014;6(222):222ra17.

Myeloperoxidase upregulates endothelin receptor type B expression
Lau D, Szöcs K, Klinke A, Rudolph T, Rudolph V, Streichert T, Blankenberg S, Baldus S
J MOL CELL CARDIOL. 2014;69:76-82.

CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity
Ludewig P, Flachsbarth K, Wegscheid C, Tiegs G, Richard G, Wagener C, Bartsch U, Horst A
INVEST OPHTH VIS SCI. 2014;55(12):7950-7960.

Bradykinin in health and disease: proceedings of the Bradykinin Symposium 2012, Berlin 23-24 August 2012
Magerl M, Bader M, Gompel A, Joseph K, Kaplan A, Kojda G, Renné T, Wirth M, Maurer M, Church M
INFLAMM RES. 2014;63(3):173-8.

Factor XII inhibition reduces thrombus formation in a primate thrombosis model
Matafonov A, Leung P, Gailani A, Grach S, Puy C, Cheng Q, Sun M, McCarty O, Tucker E, Kataoka H, Renné T, Morrissey J, Gruber A, Gailani D
BLOOD. 2014;123(11):1739-46.

Combined D2-/L2-hydroxyglutaric aciduria (SLC25A1 deficiency): clinical course and effects of citrate treatment
Mühlhausen C, Salomons G, Lukacs Z, Struys E, van der Knaap M, Ullrich K, Santer R
J INHERIT METAB DIS. 2014;37(5):775-781.

Elapid snake venom analyses show the specificity of the peptide composition at the level of genera Naja and Notechis
Munawar A, Trusch M, Georgieva D, Hildebrand D, Kwiatkowski M, Behnken H, Harder S, Arni R, Spencer P, Schlüter H, Betzel C
Toxins. 2014;6(3):850-68.

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis
Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber A, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2014;192(3):1209-19.

Molecular changes in pre-metastatic lymph nodes of esophageal cancer patients
Otto B, Koenig A, Tolstonog G, Jeschke A, Klätschke K, Vashist Y, Wicklein D, Wagener C, Izbicki J, Streichert T
PLOS ONE. 2014;9(7):e102552.

Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis
Pan Y, Carbe C, Kupich S, Pickhinke U, Ohlig S, Frye M, Seelige R, Pallerla S, Moon A, Lawrence R, Esko J, Zhang X, Grobe K
MATRIX BIOL. 2014;35:253-65.

Effects of extracellular phosphate on gene expression in murine osteoblasts
Rendenbach C, Yorgan T, Heckt T, Otto B, Baldauf C, Jeschke A, Streichert T, David J, Amling M, Schinke T
CALCIFIED TISSUE INT. 2014;94(5):474-83.

Interaction of glutaric aciduria type 1-related glutaryl-CoA dehydrogenase with mitochondrial matrix proteins
Schmiesing J, Schlüter H, Ullrich K, Braulke T, Mühlhausen C
PLOS ONE. 2014;9(2):e87715.

Differences of 25-hydroxyvitamin D3 concentrations in children and adults with neurofibromatosis type 1
Schnabel C, Dahm S, Streichert T, Thierfelder W, Kluwe L, Mautner V
CLIN BIOCHEM. 2014;47(7-8):560-3.

Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature
Shen J, Frye M, Lee B, Reinardy J, McClung J, Ding K, Kojima M, Xia H, Seidel C, Lima e Silva R, Dong A, Hackett S, Wang J, Howard B, Vestweber D, Kontos C, Peters K, Campochiaro P
J CLIN INVEST. 2014;124(10):4564-76.

MALDI imaging on tissue microarrays identifies molecular features associated with renal cell cancer phenotype
Steurer S, Seddiqi A, Singer J, Bahar A, Eichelberg C, Rink M, Dahlem R, Huland H, Sauter G, Simon R, Minner S, Burandt E, Stahl P, Schlomm T, Wurlitzer M, Schlüter H
ANTICANCER RES. 2014;34(5):2255-61.

MALDI imaging-based identification of prognostically relevant signals in bladder cancer using large-scale tissue microarrays
Steurer S, Singer J, Rink M, Chun F, Dahlem R, Simon R, Burandt E, Stahl P, Terracciano L, Schlomm T, Wagner W, Höppner W, Omidi M, Kraus O, Kwiatkowski M, Doh O, Fisch M, Soave A, Sauter G, Wurlitzer M, Schlüter H, Minner S
UROL ONCOL-SEMIN ORI. 2014;32(8):1225-33.

Pseudechis guttatus venom proteome: Insights into evolution and toxin clustering
Viala V, Hildebrand D, Trusch M, Arni R, Pimenta D, Schlüter H, Betzel C, Spencer P
J PROTEOMICS. 2014;110:32-44.

Overexpression of Gremlin-1 in Patients with Loeys-Dietz Syndrome: Implications on Pathophysiology and Early Disease Detection
Wellbrock J, Sheikhzadeh S, Oliveira Ferrer L, Stamm H, Hillebrand M, Keyser B, Klokow M, Vohwinkel G, Bonk V, Otto B, Streichert T, Balabanov S, Hagel C, Rybczynski M, Bentzien F, Bokemeyer C, Kodolitsch Y, Fiedler W
PLOS ONE. 2014;9(8):e104742.

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin
Wessel F, Winderlich M, Holm M, Frye M, Rivera-Galdos R, Vockel M, Linnepe R, Ipe U, Stadtmann A, Zarbock A, Nottebaum A, Vestweber D
NAT IMMUNOL. 2014;15(3):223-30.

Dendritic cell motility and T cell activation requires regulation of Rho-cofilin signaling by the Rho-GTPase activating protein myosin IXb
Xu Y, Pektor S, Balkow S, Hemkemeyer S, Liu Z, Grobe K, Hanley P, Shen L, Bros M, Schmidt T, Bähler M, Grabbe S
J IMMUNOL. 2014;192(8):3559-68.

A method comprising the alteration of FoxP3 isoforms in Treg cells
Andersson J, Mailer R
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Toxicogenetics--cytochrome P450 microarray analysis in forensic cases focusing on morphine/codeine and diazepam.
Andresen H, Augustin C, Streichert T
INT J LEGAL MED. 2013;127(2):395-404.

Impact of fluorination on proteolytic stability of peptides in human blood plasma.
Asante V, Mortier J, Schlüter H, Koksch B
BIOORGAN MED CHEM. 2013;21(12):3542-3546.

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy
Benz P, Merkel C, Offner K, Abeßer M, Ullrich M, Fischer T, Bayer B, Wagner H, Gambaryan S, Ursitti J, Adham I, Linke W, Feller S, Fleming I, Renné T, Frantz S, Unger A, Schuh K
CELL COMMUN SIGNAL. 2013;11:56.

Plasma kallikrein the bradykinin-producing enzyme
Björkqvist J, Jämsä A, Renné T
THROMB HAEMOSTASIS. 2013;110(3):399-407.

Zinc-dependent contact system activation induces vascular leakage and hypotension in rodents
Björkqvist J, Lecher B, Maas C, Renné T
BIOL CHEM. 2013;394(9):1195-204.

Hereditary angioedema: a bradykinin-mediated swelling disorder
Björkqvist J, Sala-Cunill A, Renné T
THROMB HAEMOSTASIS. 2013;109(3):368-74.

Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Choe C, Atzler D, Wild P, Carter A, Böger R, Ojeda Echevarria F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, De Deyn P, Benndorf R, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant P, Magnus T, Zeller T, Isbrandt D, Schwedhelm E
CIRCULATION. 2013;128(13):1451-61.

Fetuin-B, a liver-derived plasma protein is essential for fertilization
Dietzel E, Wessling J, Floehr J, Schäfer C, Ensslen S, Denecke B, Rösing B, Neulen J, Veitinger T, Spehr M, Tropartz T, Tolba R, Renné T, Egert A, Schorle H, Gottenbusch Y, Hildebrand A, Yiallouros I, Stöcker W, Weiskirchen R, Jahnen-Dechent W
DEV CELL. 2013;25(1):106-12.

High phosphate directly affects endothelial function by downregulating annexin II
Di Marco G, König M, Stock C, Wiesinger A, Hillebrand U, Reiermann S, Reuter S, Amler S, Köhler G, Buck F, Fobker M, Kümpers P, Oberleithner H, Hausberg M, Lang D, Pavenstädt H, Brand M
KIDNEY INT. 2013;83(2):213-22.

Human cytomegalovirus particles directly suppress CD4 T-lymphocyte activation and proliferation
Fornara O, Odeberg J, Khan Z, Stragliotto G, Peredo I, Butler L, Söderberg-Nauclér C
IMMUNOBIOLOGY. 2013;218(8):1034-40.

Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp--/rag2-- mice
Gebauer F, Wicklein D, Stübke K, Nehmann N, Schmidt A, Salamon J, Peldschus K, Nentwich M, Adam G, Tolstonog G, Bockhorn M, Izbicki J, Wagener C, Schumacher U
GUT. 2013;62(5):741-50.

Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia
Harder L, Eschenburg G, Zech A, Kriebitzsch N, Otto B, Streichert T, Behlich A, Dierck K, Klingler B, Hansen A, Stanulla M, Zimmermann M, Kremmer E, Stocking C, Horstmann M
J EXP MED. 2013;210(11):2289-304.

Proteolytic processing of angiotensin-I in human blood plasma.
Hildebrand D, Merkel P, Eggers L, Schlüter H
PLOS ONE. 2013;8(5):64027.

Relevant bleeding diathesis due to acquired factor XIII deficiency
Janning M, Holstein K, Spath B, Schnabel C, Bannas P, Bokemeyer C, Langer F
HAMOSTASEOLOGIE. 2013;33 Suppl 1:S50-4.

Infection and transmission dynamics of rKSHV.219 in primary endothelial cells
Jeffery H, Wheat R, Blackbourn D, Nash G, Butler L
J VIROL METHODS. 2013;193(1):251-9.

Functional interaction of SCAI with the SWI/SNF complex for transcription and tumor cell invasion
Kreßner C, Nollau P, Grosse R, Brandt D
PLOS ONE. 2013;8(8):e69947.

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke
Ludewig P, Sedlacik J, Gelderblom M, Bernreuther C, Korkusuz Y, Wagener C, Gerloff C, Fiehler J, Magnus T, Horst A
CIRC RES. 2013;113(8):1013-22.

Molecular characterization and evolution of haemocyanin from the two freshwater shrimps Caridina multidentata (Stimpson, 1860) and Atyopsis moluccensis (De Haan, 1849)
Marxen J, Pick C, Kwiatkowski M, Burmester T
J COMP PHYSIOL B. 2013;183(5):613-24.

Plasma membrane-associated malate dehydrogenase of maize (Zea mays L.) roots: Native versus recombinant protein
Menckhoff L, Mielke-Ehret N, Buck F, Vuletić M, Lüthje S
J PROTEOMICS. 2013;80C:66-77.

Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation
Nickel K, Spronk H, Mutch N, Renné T
BLOOD. 2013;122(23):3847-9.

Protein domain histochemistry (PDH): binding of the carbohydrate recognition domain (CRD) of recombinant human glycoreceptor CLEC10A (CD301) to formalin-fixed, paraffin-embedded breast cancer tissues.
Nollau P, Wolters-Eisfeld G, Seyed Mortezai N, Kurze A, Klampe B, Debus A, Bockhorn M, Niendorf A, Wagener C
J HISTOCHEM CYTOCHEM. 2013;61(3):199-205.

Increased expression of heparanase in symptomatic carotid atherosclerosis.
Osterholm C, Folkersen L, Lengquist M, Pontén F, Renné T, Li J, Hedin U
ATHEROSCLEROSIS. 2013;226(1):67-73.

Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.
Otto B, Gruner K, Heinlein C, Wegwitz F, Nollau P, Ylstra B, Pantel K, Schumacher U, Baumbusch L, Martin-Subero J, Siebert R, Wagener C, Streichert T, Deppert W, Tolstonog G
INT J CANCER. 2013;132(6):1300-1310.

Transcription factors link mouse WAP-T mammary tumors with human breast cancer
Otto B, Streichert T, Wegwitz F, Gevensleben H, Klätschke K, Wagener C, Deppert W, Tolstonog G
INT J CANCER. 2013;132(6):1311-1322.

Late-onset Pompe disease is prevalent in unclassified limb-girdle muscular dystrophies
Preisler N, Lukacs Z, Vinge L, Madsen K, Husu E, Hansen R, Duno M, Andersen H, Laub M, Vissing J
MOL GENET METAB. 2013;110(3):287-9.

MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer
Quaas A, Bahar A, Loga K, Seddiqi A, Singer J, Omidi M, Kraus O, Kwiatkowski M, Trusch M, Minner S, Burandt E, Stahl P, Wilczak W, Wurlitzer M, Simon R, Sauter G, Marx A, Schlüter H
HISTOPATHOLOGY. 2013;63(4):455-62.

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.
Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Hübner A, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T
J NEUROENDOCRINOL. 2013;25(1):14-22.

Mass spectrometric analysis of protein species of biologics
Richter V, Kwiatkowski M, Omidi M, Omidi A, Robertson W, Schlüter H
Pharmaceut Bioproc. 2013; 1(4):381-404.

Magnetic resonance T1 relaxation time of venous thrombus is determined by iron processing and predicts susceptibility to lysis
Saha P, Andia M, Modarai B, Blume U, Humphries J, Patel A, Phinikaridou A, Evans C, Mattock K, Grover S, Ahmad A, Lyons O, Attia R, Renné T, Premaratne S, Wiethoff A, Botnar R, Schaeffter T, Waltham M, Smith A
CIRCULATION. 2013;128(7):729-36.

The kallikreins: old proteases with new clinical potentials
Schmitt M, Renné T, Scorilas A
THROMB HAEMOSTASIS. 2013;110(3):396-8.

Effect of vitamin D3 treatment on bone density in neurofibromatosis 1 patients: a retrospective clinical study.
Schnabel C, Jett K, Friedman J, Frieling I, Kruse H, Mautner V
JOINT BONE SPINE. 2013;80(3):315-319.

Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients
Schröder C, Milde-Langosch K, Gebauer F, Schmid K, Müller V, Wirtz R, Meyer-Schwesinger C, Schluter H, Sauter G, Schumacher U
J CANCER RES CLIN. 2013;139:1745-1755.

Deciphering of ADP-induced, phosphotyrosine-dependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling
Schweigel H, Geiger J, Beck F, Buhs S, Gerull H, Walter U, Sickmann A, Nollau P
PROTEOMICS. 2013;13(6):1016-27.

Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo
Seelige R, Natsch C, März S, Jing D, Frye M, Butz S, Vestweber D
J IMMUNOL. 2013;190(3):892-6.

Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.
Seitz S, Rendenbach C, Barvencik F, Streichert T, Jeschke A, Schulze J, Amling M, Schinke T
BONE. 2013;53(1):231-238.

Tumor-associated Neu5Ac-Tn and Neu5Gc-Tn antigens bind to C-type lectin CLEC10A (CD301, MGL)
Seyed Mortezai N, Behnken H, Kurze A, Ludewig P, Buck F, Meyer B, Wagener C
GLYCOBIOLOGY. 2013;23(7):844-52.

Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin
Stemmer N, Strekalova E, Djogo N, Plöger F, Loers G, Lutz D, Buck F, Michalak M, Schachner M, Kleene R
PLOS ONE. 2013;8(4):e61299.

MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays.
Steurer S, Borkowski C, Odinga S, Buchholz M, Koop C, Huland H, Becker M, Witt M, Trede D, Omidi M, Kraus O, Bahar A, Seddiqi A, Singer J, Kwiatkowski M, Trusch M, Simon R, Wurlitzer M, Minner S, Schlomm T, Sauter G, Schlüter H
INT J CANCER. 2013;133(4):920-928.

Screening of high-risk Gaucher disease patients using dried blood spots techniques
Vairo F, Netto C, Tirelli K, Siebert M, Burin M, Saraiva-Pereira M, Balreira A, Sá Miranda M, Lukacs Z, Schwartz I
GENE. 2013;523(1):114-5.

Diagnosis of Pompe disease: muscle biopsy vs blood-based assays
Vissing J, Lukacs Z, Straub V
JAMA NEUROL. 2013;70(7):923-7.

Diagnosing mucopolysaccharidosis IVA
Wood T, Harvey K, Beck M, Burin M, Chien Y, Church H, D'Almeida V, van Diggelen O, Fietz M, Giugliani R, Harmatz P, Hawley S, Hwu W, Ketteridge D, Lukacs Z, Miller N, Pasquali M, Schenone A, Thompson J, Tylee K, Yu C, Hendriksz C
J INHERIT METAB DIS. 2013;36(2):293-307.

MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40
Xu N, Meisgen F, Butler L, Han G, Wang X, Söderberg-Nauclér C, Ståhle M, Pivarcsi A, Sonkoly E
J IMMUNOL. 2013;190(2):678-88.

High prevalence of human cytomegalovirus in carotid atherosclerotic plaques obtained from Russian patients undergoing carotid endarterectomy
Yaiw K, Ovchinnikova O, Taher C, Mohammad A, Davoudi B, Shlyakhto E, Rotar O, Konradi A, Wilhelmi V, Rahbar A, Butler L, Assinger A, Söderberg-Nauclér C
Herpesviridae. 2013;4(1):3.

The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons
Zivraj K, Rehbein M, Ölschläger-Schütt J, Schob C, Falley K, Buck F, Schweizer M, Schepis A, Kremmer E, Richter D, Kreienkamp H, Kindler S
J NEUROCHEM. 2013;124(5):670-84.

Comparison of displacement versus gradient mode for separation of a complex protein mixture by anion-exchange chromatography
Ahrends R, Lichtner B, Buck F, Hildebrand D, Kotasinska M, Kohlbacher O, Kwiatkowski M, Wagner M, Trusch M, Schlüter H
J CHROMATOGR B. 2012;901:34-40.

Inferring proteolytic processes from mass spectrometry time series data using degradation graphs.
Aiche S, Reinert K, Schütte C, Hildebrand D, Schlüter H, Conrad T
PLOS ONE. 2012;7(7):40656.

Acceleration of collateral development by carcinoembryonic antigen-related cell adhesion molecule 1 expression on CD11b/⁺Gr-1⁺ myeloid cells--brief report
Bickert T, Marshall R, Zhang Z, Ludewig P, Binder M, Klinke A, Rottbauer W, Amling M, Wagener C, Ito W, Horst A
ARTERIOSCL THROM VAS. 2012;32(11):2566-8.

Amino acids: chemistry, functionality and selected non-enzymatic post-translational modifications.
Bischoff R, Schlüter H
J PROTEOMICS. 2012;75(8):2275-2296.

Emerging functions of the plasma contact system for hereditary angioedema.
Björkqvist J, Müller F, Renné T
journal of angioedema. 2012;(J. Angioedema ):56-63.

Neutrophil extracellular traps promote deep vein thrombosis in mice
Brill A, Fuchs T, Savchenko A, Thomas G, Martinod K, De Meyer S, Bhandari A, Wagner D
J THROMB HAEMOST. 2012;10(1):136-44.

Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice
Brill A, Yesilaltay A, De Meyer S, Kisucka J, Fuchs T, Kocher O, Krieger M, Wagner D
ARTERIOSCL THROM VAS. 2012;32(8):1841-7.

sarA negatively regulates Staphylococcus epidermidis biofilm formation by modulating expression of 1 MDa extracellular matrix binding protein and autolysis-dependent release of eDNA.
Christner M, Heinze C, Busch M, Franke G, Hentschke M, Sara B, Büttner H, Kotasinska M, Wischnewski V, Kroll G, Buck F, Molin S, Otto M, Rohde H
MOL MICROBIOL. 2012;86(2):394-410.

Purification, crystallization and preliminary X-ray diffraction analysis of crotamine, a myotoxic polypeptide from the Brazilian snake Crotalus durissus terrificus
Coronado M, Georgieva D, Buck F, Gabdoulkhakov A, Ullah A, Spencer P, Arni R, Betzel C
ACTA CRYSTALLOGR F. 2012;68(Pt 9):1052-4.

Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation.
Darbousset R, Thomas G, Mezouar S, Frère C, Bonier R, Mackman N, Renné T, Dignat-George F, Dubois C, Panicot-Dubois L
BLOOD. 2012;120(10):2133-2143.

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis
Demers M, Krause D, Schatzberg D, Martinod K, Voorhees J, Fuchs T, Scadden D, Wagner D
P NATL ACAD SCI USA. 2012;109(32):13076-81.

Extracellular chromatin is an important mediator of ischemic stroke in mice
De Meyer S, Suidan G, Fuchs T, Monestier M, Wagner D
ARTERIOSCL THROM VAS. 2012;32(8):1884-91.

Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.
Deuse T, Hua X, Taylor V, Stubendorff M, Baluom M, Chen Y, Park G, Velden J, Streichert T, Reichenspurner H, Robbins R, Schrepfer S
TRANSPLANTATION. 2012;94(7):695-702.

AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease.
Fraune C, Lange S, Krebs C, Hölzel A, Baucke J, Divac N, Schwedhelm E, Streichert T, Velden J, Garrelds I, Danser A, Frenay A, van Goor H, Jankowski V, Stahl R, Nguyen G, Wenzel U
AM J PHYSIOL-RENAL. 2012;303(7):1037-1048.

Neutrophil extracellular trap (NET) impact on deep vein thrombosis
Fuchs T, Brill A, Wagner D
ARTERIOSCL THROM VAS. 2012;32(8):1777-83.

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies
Fuchs T, Kremer Hovinga J, Schatzberg D, Wagner D, Lämmle B
BLOOD. 2012;120(6):1157-64.

Crystal structure of a dimeric Ser49- PLA₂-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity
Georgieva D, Coronado M, Oberthür D, Buck F, Duhalov D, Arni R, Betzel C
MOL BIOSYST. 2012;8(5):1405-11.

Hyaluronan in intra-operative edema of NF1-associated neurofibromas.
Hagel C, Behrens T, Prehm P, Schnabel C, Glatzel M, Friedrich R
NEUROPATHOLOGY. 2012;32(4):406-414.

Recombinant p53 displays heterogeneity during isoelectric focusing
Heukeshoven J, März A, Warnecke G, Deppert W, Tolstonog G
ELECTROPHORESIS. 2012;33(18):2818-2827.

The influence of serotonin on fear learning.
Hindi Attar C, Finckh B, Büchel C
PLOS ONE. 2012;7(8):42397.

Successful eradication of a FVIII inhibitor in a 60-year-old patient with mild haemophilia A using single-agent prednisolone.
Holstein K, Marx G, Lentz B, Bokemeyer C, Langer F
HAMOSTASEOLOGIE. 2012;32 Suppl 1:48-51.

Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis.
Keller J, Catalá-Lehnen P, Wintges K, Schulze J, Bickert T, Ito W, Horst A, Amling M, Schinke T
BIOCHEM BIOPH RES CO. 2012;417(1):217-222.

A child with night blindness: preventing serious symptoms of Refsum disease.
Kohlschütter A, Santer R, Lukacs Z, Altenburg C, Kemper M, Rüther K
J CHILD NEUROL. 2012;27(5):654-656.

Cation exchange displacement batch chromatography of proteins guided by screening of protein purification parameters.
Kotasinska M, Richter V, Thiemann J, Schlüter H
J SEP SCI. 2012;35(22):3170-3176.

Regulatory mechanisms of the plasma contact system.
Maas C, Renné T
THROMB RES. 2012;129 Suppl 2:73-76.

Deciphering Phosphotyrosine-Dependent Signaling Networks in Cancer by SH2 Profiling.
Machida K, Khenkhar M, Nollau P
Genes Cancer. 2012;3(5-6):353-361.

Mannose 6 dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5.
Makrypidi G, Damme M, Müller-Loennies S, Trusch M, Schmidt B, Schlüter H, Heeren J, Lübke T, Saftig P, Braulke T
MOL CELL BIOL. 2012;32(4):774-782.

Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.
Meganathan K, Jagtap S, Wagh V, Winkler J, Gaspar J, Hildebrand D, Trusch M, Lehmann K, Hescheler J, Sachinidis A, Schlüter H
PLOS ONE. 2012;7(8):44228.

Combining lectin affinity chromatography and immunodepletion - A novel method for the enrichment of disease-specific glycoproteins in human plasma.
Mortezai N, Wagener C, Buck F
METHODS. 2012;56(2):254-259.

Crosstalk of the plasma contact system with bacteria.
Nickel K, Renné T
THROMB RES. 2012;130 Suppl 1:78-83.

L1CAM increases MAP2 expression via the MAPK pathway to promote neurite outgrowth.
Poplawski G, Tranziska A, Leshchyns´ka I, Meier I, Streichert T, Sytnyk V, Schachner M
MOL CELL NEUROSCI. 2012;50(2):169-178.

Tailor-made quantum dot and iron oxide based contrast agents for in vitro and in vivo tumor imaging.
Pöselt E, Schmidtke C, Fischer S, Peldschus K, Salamon J, Kloust H, Tran H, Pietsch A, Heine M, Adam G, Schumacher U, Wagener C, Förster S, Weller H
ACS NANO. 2012;6(4):3346-3355.

Fat and carbohydrate metabolism during exercise in late-onset Pompe disease.
Preisler N, Laforet P, Madsen K, Hansen R, Lukacs Z, Ørngreen M, Lacour A, Vissing J
MOL GENET METAB. 2012;107(3):462-468.

Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.
Quante T, Otto B, Brázdová M, Kejnovská I, Deppert W, Tolstonog G
CELL CYCLE. 2012;11(17):3290-3303.

Antigen-specificity of oligoclonal abnormal protein bands in multiple myeloma after allogeneic stem cell transplantation.
Rahlff J, Trusch M, Haag F, Bacher U, Horst A, Schlüter H, Binder M
CANCER IMMUNOL IMMUN. 2012;61(10):1639-1651.

The procoagulant and proinflammatory plasma contact system.
Renné T
SEMIN IMMUNOPATHOL. 2012;34(1):31-41.

The plasma contact system
Renné T, Colman R, Mader V, Clowes A, George J, Goldhaber S
2012. Thrombosis and Hemostasis. LIPPINCOTT WILLIAMS & WILKINS, .

Plasma kallikrein: novel functions for an old protease.
Renné T, Gruber A
THROMB HAEMOSTASIS. 2012;107(6):1012-1013.

In vivo roles of factor XII.
Renné T, Schmaier A, Nickel K, Blombäck M, Maas C
BLOOD. 2012;120(22):4296-4303.

p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze J, Riecken K, Baranowsky A, Streichert T, Lange T, Spiro A, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T
CANCER LETT. 2012;317(1):106-113.

Microbiological analysis of a prospective, randomized, double-blind trial comparing moxifloxacin and clindamycin in the treatment of odontogenic infiltrates and abscesses.
Sobottka I, Wegscheider K, Balzer O, Böger R, Hallier O, Giersdorf I, Streichert T, Haddad M, Platzer U, Cachovan G
ANTIMICROB AGENTS CH. 2012;56(5):2565-2569.

XMRV induces cell migration, cytokine expression and tumor angiogenesis: are 22Rv1 cells a suitable prostate cancer model?
Stieler K, Schumacher U, Horst A, Fischer N
PLOS ONE. 2012;7(7):42321.

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice
Thomas G, Carbo C, Curtis B, Martinod K, Mazo I, Schatzberg D, Cifuni S, Fuchs T, von Andrian U, Hartwig J, Aster R, Wagner D
BLOOD. 2012;119(26):6335-43.

T granules in human platelets function in TLR9 organization and signaling
Thon J, Peters C, Machlus K, Aslam R, Rowley J, Macleod H, Devine M, Fuchs T, Weyrich A, Semple J, Flaumenhaft R, Italiano J
J CELL BIOL. 2012;198(4):561-74.

Displacement chromatography as first separating step in online two-dimensional liquid chromatography coupled to mass spectrometry analysis of a complex protein sample--the proteome of neutrophils
Trusch M, Tillack K, Kwiatkowski M, Bertsch A, Ahrends R, Kohlbacher O, Martin R, Sospedra M, Schlüter H
J CHROMATOGR A. 2012;1232:288-294.

Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa.
Van Der Meijden P, Van Schilfgaarde M, Van Oerle R, Renné T, Ten Cate H, Spronk H
J THROMB HAEMOST. 2012;10(7):1355-1362.

Nilotinib and imatinib are comparably effective in reducing growth of human eosinophil leukemia cells in a newly established xenograft model.
Wicklein D, Ramos Leal N, Salamon J, Thamer M, Herrmann H, Valent P, Schumacher U, Ullrich S
PLOS ONE. 2012;7(2):30567.

Expert recommendations for the laboratory diagnosis of MPS VI.
Wood T, Bodamer O, Burin M, D'Almeida V, Fietz M, Giugliani R, Hawley S, Hendriksz C, Hwu W, Ketteridge D, Lukacs Z, Mendelsohn N, Miller N, Pasquali M, Schenone A, Schoonderwoerd K, Winchester B, Harmatz P
MOL GENET METAB. 2012;106(1):73-82.

Up-regulation of the cardiac lipid metabolism at the onset of heart failure.
Abdalla S, Fu X, Elzahwy S, Klaetschke K, Streichert T, Quitterer U
Cardiovascular & hematological agents in medicinal chemistry. 2011;9(3):190-206.

Isolation, purification, crystallization and preliminary crystallographic studies of a chitinase from Crocus vernus.
Akrem A, Iqbal S, Buck F, Meyer A, Perbandt M, Voelter W, Betzel C
ACTA CRYSTALLOGR F. 2011;67(Pt 3):340-343.

Control of bone formation by the serpentine receptor Frizzled-9.
Albers J, Schulze J, Beil F, Gebauer M, Baranowsky A, Keller J, Marshall R, Wintges K, Friedrich F, Priemel M, Schilling A, Rueger J, Cornils K, Fehse B, Streichert T, Sauter G, Jakob F, Insogna K, Pober B, Knobeloch K, Francke U, Amling M, Schinke T
J CELL BIOL. 2011;192(6):1057-1072.

Effects of increased bone formation on fracture healing in mice.
Beil F, Barvencik F, Gebauer M, Beil B, Pogoda P, Rueger J, Ignatius A, Schinke T, Amling M
J TRAUMA. 2011;70(4):857-862.

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models
Brill A, Fuchs T, Chauhan A, Yang J, De Meyer S, Köllnberger M, Wakefield T, Lämmle B, Massberg S, Wagner D
BLOOD. 2011;117(4):1400-7.

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo
Broermann A, Winderlich M, Block H, Frye M, Rossaint J, Zarbock A, Cagna G, Linnepe R, Schulte D, Nottebaum A, Vestweber D
J EXP MED. 2011;208(12):2393-401.

Comparative efficacy and safety of moxifloxacin and clindamycin in the treatment of odontogenic abscesses and inflammatory infiltrates: a phase II, double-blind, randomized trial.
Cachovan G, Böger R, Giersdorf I, Hallier O, Streichert T, Haddad M, Platzer U, Schön G, Wegscheider K, Sobottka I
ANTIMICROB AGENTS CH. 2011;55(3):1142-1147.

CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.
Choe C, Lardong K, Gelderblom M, Ludewig P, Leypoldt F, Koch Nolte F, Gerloff C, Magnus T
PLOS ONE. 2011;6(5):19046.

Post-translational modifications of the gamma-subunit affect intracellular trafficking and complex assembly of GlcNAc-1-phosphotransferase.
Encarnação M, Kollmann K, Trusch M, Braulke T, Pohl S
J BIOL CHEM. 2011;286(7):5311-5318.

Histones induce rapid and profound thrombocytopenia in mice
Fuchs T, Bhandari A, Wagner D
BLOOD. 2011;118(13):3708-14.

Factor XI and the Plasma Contact System
Gailani D, Renné T
2011. Metabolic & Molecular Bases of Inherited Disease. 9. Aufl. .

CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.
Gerstel D, Wegwitz F, Jannasch K, Ludewig P, Scheike K, Alves F, Beauchemin N, Deppert W, Wagener C, Horst A
ONCOGENE. 2011;30(41):4275-4288.

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation
Hakkim A, Fuchs T, Martinez N, Hess S, Prinz H, Zychlinsky A, Waldmann H
NAT CHEM BIOL. 2011;7(2):75-7.

A novel and divergent role of granzyme A and B in resistance to helminth infection.
Hartmann W, Marsland B, Otto B, Urny J, Fleischer B, Korten S
J IMMUNOL. 2011;186(4):2472-2481.

Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.
Heine M, Nollau P, Maßlo C, Nielsen P, Freund B, Bruns O, Reimer R, Hohenberg H, Peldschus K, Ittrich H, Schumacher U
PLOS ONE. 2011;6(12):28030.

Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein S, Müller V, Köhler N, Wikman H, Krenkel S, Streichert T, Schweizer M, Riethdorf S, Assmann V, Henningsen M, Beck K, Issa R, Jänicke F, Pantel K, Milde-Langosch K
BREAST CANCER RES TR. 2011;129(2):347-360.

Decreased active von Willebrand factor level owing to shear stress in aortic stenosis patients.
Hollestelle M, Loots C, Squizzato A, Renné T, Bouma B, de Groot P, Lenting P, Meijers J, Gerdes V
J THROMB HAEMOST. 2011;9(5):953-958.

Monoclonal antibodies for the identification and purification of vNAR domains and IgNAR immunoglobulins from the horn shark Heterodontus francisci.
Juarez K, Dubberke G, Lugo P, Koch Nolte F, Buck F, Haag F, Licea A
HYBRIDOMA. 2011;30(4):323-329.

Towards the analysis of protein species: an overview about strategies and methods.
Jungblut P, Schlüter H
AMINO ACIDS. 2011;41(2):219-222.

Brachyury expression predicts poor prognosis at early stages of colorectal cancer.
Kilic N, Feldhaus S, Kilic E, Tennstedt P, Wicklein D, Wasielewski R, Viebahn C, Kreipe H, Schumacher U
EUR J CANCER. 2011;47(7):1080-1085.

Factor XII activation is essential to sustain the procoagulant effects of particulate matter.
Kilinç E, Van Oerle R, Borissoff J, Oschatz C, Gerlofs-Nijland M, Janssen N, Cassee F, Sandström T, Renné T, Ten Cate H, Spronk H
J THROMB HAEMOST. 2011;9(7):1359-1367.

Impaired melanoma growth in VASP deficient mice.
Kim Y, Renné C, Seifert S, Schuh K, Renné T
FEBS LETT. 2011;585(15):2533-2536.

Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress.
Kröller-Schön S, Schulz E, Wenzel P, Kleschyov A, Hortmann M, Torzewski M, Oelze M, Renné T, Daiber A, Münzel T
BASIC RES CARDIOL. 2011;106(6):1147-1158.

Strategies for the identification of arginine ADP-ribosylation sites.
Laing S, Koch Nolte F, Haag F, Buck F
J PROTEOMICS. 2011;75(1):169-176.

Analysis of Potential Biomarkers and Modifier Genes Affecting the Clinical Course of CLN3 Disease.
Lebrun A, Moll-Khasrawi P, Pohl S, Makrypidi G, Storch S, Kilian D, Streichert T, Otto B, Mole S, Ullrich K, Cotman S, Kohlschütter A, Braulke T, Schulz A
MOL MED. 2011;17(11-12):1253-1261.

Dried blood spots in the diagnosis of lysosomal storage disorders--possibilities for newborn screening and high-risk population screening.
Lukacs Z, Nieves Cobos P, Keil A, Hartung R, Mengel E, Beck M, Deschauer M, Hanisch F, Santer R
CLIN BIOCHEM. 2011;44(7):476.

The plasma contact system 2.0.
Maas C, Oschatz C, Renné T
SEMIN THROMB HEMOST. 2011;37(4):375-381.

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity
Metzler K, Fuchs T, Nauseef W, Reumaux D, Roesler J, Schulze I, Wahn V, Papayannopoulos V, Zychlinsky A
BLOOD. 2011;117(3):953-9.

ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
Minner S, Enodien M, Sirma H, Lübke A, Krohn A, Mayer P, Simon R, Tennstedt P, Müller J, Scholz L, Brase J, Liu A, Schlüter H, Pantel K, Schumacher U, Bokemeyer C, Steuber T, Graefen M, Sauter G, Schlomm T
CLIN CANCER RES. 2011;17(18):5878-5888.

Factor XI and XII as antithrombotic targets.
Müller F, Gailani D, Renné T
CURR OPIN HEMATOL. 2011;18(5):349-355.

Targeting FXI and FXII for anticoagulation
Müller F, Gailani D, Renné T
CURR OPIN HEMATOL. 2011;(18):349-355.

Platelet polyphosphates: the nexus of primary and secondary hemostasis.
Müller F, Renné T
SCAND J CLIN LAB INV. 2011;71(2):82-86.

Venom peptide analysis of Vipera ammodytes meridionalis (Viperinae) and Bothrops jararacussu (Crotalinae) demonstrates subfamily-specificity of the peptidome in the family Viperidae
Munawar A, Trusch M, Georgieva D, Spencer P, Frochaux V, Harder S, Arni R, Duhalov D, Genov N, Schlüter H, Betzel C
MOL BIOSYST. 2011;7(12):3298-3307.

Generating high-quality protein binders: a large screening effort pays off.
Nollau P
NAT METHODS. 2011;8(7):545-546.

Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.
Oschatz C, Maas C, Lecher B, Jansen T, Björkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin W, Nilsson G, Renné T
IMMUNITY. 2011;34(2):258-268.

Lack of evidence for pleiotropic effects of clopidogrel on endothelial function and inflammation in patients with stable coronary artery disease: results of the double-blind, randomized CASSANDRA study.
Ostad M, Nick E, Paixao-Gatinho V, Schnorbus B, Schiewe R, Tschentscher P, Munzel T, Warnholtz A
CLIN RES CARDIOL. 2011;100(1):29-36.

Protection from glycine at low doses in ischemia-reperfusion injury of the rat small intestine.
Petrat F, Drowatzky J, Boengler K, Finckh B, Schmitz K, Schulz R, de Groot H
EUR SURG RES. 2011;46(4):180-187.

The Kallikrein-kinin system and thrombosis
Renné T
2011. Kinins. Bader M (Hrsg.). 1. Aufl. Walter De Gruyter GmbH & Co. KG, Berlin/Boston, 203-210.

Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation.
Richter U, Schröder C, Wicklein D, Lange T, Geleff S, Dippel V, Schumacher U, Klutmann S
HISTOCHEM CELL BIOL. 2011;135(5):499-512.

Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction.
Rudolph V, Goldmann B, Boes C, Rudolph T, Klinke A, Friedrichs K, Lau D, Wegscheider K, Haddad M, Meinertz T, Baldus S
INT J CARDIOL. 2011;153(3):267-271.

Special issue on protein species.
Schlüter H, Jungblut P
AMINO ACIDS. 2011;41(2):217-218.

Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.
Schulze J, Bickert T, Beil F, Zaiss M, Albers J, Wintges K, Streichert T, Klätschke K, Keller J, Hissnauer T, Spiro A, Gessner A, Schett G, Amling M, McKenzie A, Horst A, Schinke T
J BONE MINER RES. 2011;26(4):704-717.

Vergleichende psychologische Aspekte von Juckreiz und Schmerz
Schwender-Groen L, Worm M, Klinger R
SCHMERZ. 2011;25(2):207-18; quiz 219-20.

MicroRNA profiling using fluorescence-labeled beads: data acquisition and processing.
Streichert T, Otto B, Lehmann U
Methods Mol Biol. 2011;676:253-268.

Determination of hemolysis thresholds by the use of data loggers in pneumatic tube systems
Streichert T, Otto B, Schnabel C, Nordholt G, Haddad M, Maric M, Petersmann A, Jung R, Wagener C
CLIN CHEM. 2011;57(10):1390-1397.

Identification of SPRED2 (sprouty-related protein with EVH1 domain 2) as a negative regulator of the hypothalamic-pituitary-adrenal axis.
Ullrich M, Bundschu K, Benz P, Abesser M, Freudinger R, Fischer T, Ullrich J, Renné T, Walter U, Schuh K
J BIOL CHEM. 2011;286(11):9477-9488.

Synapsin I is an oligomannose-carrying glycoprotein, acts as an oligomannose-binding lectin, and promotes neurite outgrowth and neuronal survival when released via glia-derived exosomes.
Wang S, Cesca F, Loers G, Schweizer M, Buck F, Benfenati F, Schachner M, Kleene R
J NEUROSCI. 2011;31(20):7275-7290.

Application of displacement chromatography for the proteome analysis of a human plasma protein fraction
Ahrends R, Lichtner B, Bertsch A, Kohlbacher O, Hildebrand D, Trusch M, Schlüter H
J CHROMATOGR A. 2010;1217(19):3321-9.

Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Bartkowiak K, Harms-Effenberger K, Harder S, Andreas A, Buck F, Peter-Katalinic J, Pantel K, Brandt B
J PROTEOME RES. 2010;9(6):3158-3168.

Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells
Binder M, Léchenne B, Ummanni R, Scharf C, Balabanov S, Trusch M, Schlüter H, Braren I, Spillner E, Trepel M
PLOS ONE. 2010;5(12):e15992.

Osteopontin (OPN) expression in thyroid carcinoma.
Briese J, Cheng S, Ezzat S, Liu W, Winer D, Wagener C, Bamberger A, Asa S
ANTICANCER RES. 2010;30(5):1681-1688.

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Cheng Q, Tucker E, Pine M, Sisler I, Matafonov A, Sun M, White-Adams T, Smith S, Hanson S, McCarty O, Renné T, Gruber A, Gailani D
BLOOD. 2010;116(19):3981-3989.

The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin.
Christner M, Franke G, Schommer N, Wendt U, Wegert K, Pehle P, Kroll G, Schulze C, Buck F, Mack D, Aepfelbacher M, Rohde H
MOL MICROBIOL. 2010;75(1):187-207.

Newborn screening for Fabry disease by measuring GLA activity using tandem mass spectrometry.
Dajnoki A, Fekete G, Keutzer J, Orsini J, Jesus D, Victor R, Chien Y, Lukacs Z, Lukacs Z, Mühl A, Zhang X, Bodamer O
CLIN CHIM ACTA. 2010;411(19-20):1428-1431.

VASP phosphorylation at serine239 regulates the effects of NO on smooth muscle cell invasion and contraction of collagen.
Defawe O, Kim S, Chen L, Huang D, Kenagy R, Renné T, Walter U, Daum G, Clowes A
J CELL PHYSIOL. 2010;222(1):230-237.

Extracellular DNA traps promote thrombosis
Fuchs T, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers D, Wrobleski S, Wakefield T, Hartwig J, Wagner D
P NATL ACAD SCI USA. 2010;107(36):15880-5.

A kit for the investigation of live Escherichia coli cell adhesion to glycosylated surfaces.
Hartmann M, Horst A, Klemm P, Lindhorst T
CHEM COMMUN. 2010;46(2):330-332.

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Hentschke M, Berneking L, Campos C, Buck F, Ruckdeschel K, Aepfelbacher M
PLOS ONE. 2010;5(10):.

Identification of molecular markers for articular cartilage.
Hissnauer T, Baranowsky A, Pestka J, Streichert T, Wiegandt K, Goepfert C, Beil F, Albers J, Schulze J, Ueblacker P, Petersen J, Schinke T, Meenen N, Pörtner R, Amling M
OSTEOARTHR CARTILAGE. 2010;18(12):1630-1638.

Herpes simplex virus type 1 entry into epithelial MDCKII cells: role of VASP activities.
Jaeger V, Hoppe S, Petermann P, Liebig T, Jansen M, Renné T, Knebel-Mörsdorf D
J GEN VIROL. 2010;91(Pt 9):2152-2157.

Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung.
Kalinina T, Güngör C, Thieltges S, Möller-Krull M, Murga-Penas E, Wicklein D, Streichert T, Schumacher U, Kalinin V, Simon R, Otto B, Dierlamm J, Schwarzenbach H, Harms-Effenberger K, Bockhorn M, Izbicki J, Yekebas E
BMC CANCER. 2010;10:295.

Identification of differentially expressed microRNAs in human male breast cancer.
Lehmann U, Streichert T, Otto B, Albat C, Hasemeier B, Christgen H, Schipper E, Hille U, Kreipe H, Länger F
BMC CANCER. 2010;10:109.

Tandem affinity depletion: a combination of affinity fractionation and immunoaffinity depletion allows the detection of low-abundance components in the complex proteomes of body fluids.
Mortezai N, Harder S, Schnabel C, Moors E, Gauly M, Schlüter H, Wagener C, Buck F
J PROTEOME RES. 2010;9(12):6126-6134.

Comparison of two techniques for the screening of human tumor cells in mouse blood: Quantitative real-time polymerase chain reaction (qRT-PCR) versus laser scanning cytometry (LSC).
Nehmann N, Wicklein D, Schumacher U, Müller R
ACTA HISTOCHEM. 2010;112(5):489-96.

Phosphopeptide screening using nanocrystalline titanium dioxide films as affinity matrix-assisted laser desorption ionization targets in mass spectrometry
Niklew M, Hochkirch U, Melikyan A, Moritz T, Kurzawski S, Schlüter H, Ebner I, Linscheid M
ANAL CHEM. 2010;82(3):1047-1053.

Quantitative MR imaging of targeted SPIO particles on the cell surface and comparison to flow cytometry.
Peldschus K, Schultze A, Nollau P, Kaul M, Schumacher U, Wagener C, Adam G, Ittrich H
MAGN RESON IMAGING. 2010;28(4):599-606.

Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI.
Pham M, Kleinschnitz C, Helluy X, Bartsch A, Austinat M, Behr V, Renné T, Nieswandt B, Stoll G, Bendszus M
NEUROIMAGE. 2010;49(4):2907-2914.

Binding of alphaII spectrin to 14-3-3beta is involved in NCAM-dependent neurite outgrowth.
Ramser E, Buck F, Schachner M, Tilling T
MOL CELL NEUROSCI. 2010;45(1):66-74.

Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation.
Raslan F, Schwarz T, Meuth S, Austinat M, Bader M, Renné T, Roosen K, Stoll G, Sirén A, Kleinschnitz C
J CEREBR BLOOD F MET. 2010;30(8):1477-1486.

Safe(r) anticoagulation.
Renné T
BLOOD. 2010;116(22):4390-4391.

Neuroligin 1 is dynamically exchanged at postsynaptic sites.
Schapitz I, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel S, Wallace K, Stempel A, Buck F, Grant S, Schweizer M, Schmitz D, Schwarz J, Holzbaur E, Kneussel M
J NEUROSCI. 2010;30(38):12733-12744.

Prospective, randomized study comparing two different minimized versus conventional cardiopulmonary bypass system.
Schönebeck J, Haddad M, Wegscheider K, Joubert-Huebner E, Reichenspurner H, Detter C
INNOVATIONS. 2010;5(4):270-277.

Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.
Schulze J, Seitz S, Saito H, Schneebauer M, Marshall R, Baranowsky A, Busse B, Schilling A, Friedrich F, Albers J, Spiro A, Zustin J, Streichert T, Ellwanger K, Niehrs C, Amling M, Baron R, Schinke T
PLOS ONE. 2010;5(4):10309.

Preproenkephalin (Penk) is expressed in differentiated osteoblasts, and its deletion in Hyp mice partially rescues their bone mineralization defect.
Seitz S, Barvencik F, Gebauer M, Albers J, Schulze J, Streichert T, Amling M, Schinke T
CALCIFIED TISSUE INT. 2010;86(4):282-293.

High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1.
Seitz S, Schnabel C, Busse B, Schmidt H, Beil F, Friedrich R, Schinke T, Mautner V, Amling M
OSTEOPOROSIS INT. 2010;21(1):119-127.

Metabolic sensing by p53: keeping the balance between life and death
Tolstonog G, Deppert W
P NATL ACAD SCI USA. 2010;107(30):13193-4.

Application of displacement chromatography for the analysis of a lipid raft proteome
Trusch M, Böhlick A, Hildebrand D, Lichtner B, Bertsch A, Kohlbacher O, Bachmann S, Schlüter H
J CHROMATOGR B. 2010;878(3-4):309-14.

Improved particle-packed HPLC/MS microchips for proteomic analysis
Trusch M, Ehlert S, Bertsch A, Kohlbacher O, Hildebrand D, Schlüter H, Tallarek U
J SEP SCI. 2010;33(21):3283-91.

Tumorigenic WAP-T mouse mammary carcinoma cells: a model for a self-reproducing homeostatic cancer cell system.
Wegwitz F, Kluth M, Mänz C, Otto B, Gruner K, Heinlein C, Kühl M, Warnecke G, Schumacher U, Deppert W, Tolstonog G
PLOS ONE. 2010;5(8):12103.

Severe glycerol intoxication after Menière's disease diagnostic--case report and overview of kinetic data.
Andresen H, Bingel U, Streichert T, Schmoldt A, Zoerner A, Tsikas D, Just I
CLIN TOXICOL. 2009;47(4):312-316.

Approaching clinical proteomics: current state and future fields of application in fluid proteomics.
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes H, Meyer H, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang H, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tarnok A, Taussig M, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Verhuven W, Wagener C, Wagner O, Schmitz G
CLIN CHEM LAB MED. 2009;47(6):724-744.

Approaching clinical proteomics: current state and future fields of application in cellular proteomics.
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes H, Meyer H, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang H, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tárnok A, Taussig M, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Wagener C, Wagner O, Schmitz G
CYTOM PART A. 2009;75(10):816-832.

Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema
Austinat M, Braeuninger S, Pesquero J, Brede M, Bader M, Stoll G, Renné T, Kleinschnitz C
STROKE. 2009;40(1):285-93.

Two-dimensional differential gel electrophoresis of a cell line derived from a breast cancer micrometastasis revealed a stem/ progenitor cell protein profile.
Bartkowiak K, Wieczorek M, Buck F, Harder S, Moldenhauer J, Harms-Effenberger K, Pantel K, Peter-Katalinic J, Brandt B
J PROTEOME RES. 2009;8(4):2004-2014.

Substrate specificity of rat DESC4, a type II transmembrane serine protease.
Behrens M, Buck F, Meyerhof W
PROTEIN PEPTIDE LETT. 2009;16(1):1-6.

Differential VASP phosphorylation controls remodeling of the actin cytoskeleton
Benz P, Blume C, Seifert S, Wilhelm S, Waschke J, Schuh K, Gertler F, Münzel T, Renné T
J CELL SCI. 2009;122(Pt 21):3954-65.

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
Brandt D, Baarlink C, Kitzing T, Kremmer E, Ivaska J, Nollau P, Grosse R
NAT CELL BIOL. 2009;11(5):557-568.

Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences
Brázdová M, Quante T, Tögel L, Walter K, Loscher C, Tichý V, Cincárová L, Deppert W, Tolstonog G
NUCLEIC ACIDS RES. 2009;37(5):1486-500.

Magnetic resonance imaging of melanoma metastases in a clinical relevant human melanoma xenograft scid mouse model.
Dahl A, Peldschus K, Ittrich H, Adam G, Altevogt P, Wagener C, Schumacher U
CANCER LETT. 2009;274(2):194-200.

Profiling the tyrosine phosphorylation state using SH2 domains.
Dierck K, Machida K, Mayer B, Nollau P
Methods Mol Biol. 2009;527:131-155.

The ADMA/DDAH pathway regulates VEGF-mediated angiogenesis
Fiedler L, Bachetti T, Leiper J, Zachary I, Chen L, Renné T, Wojciak-Stothard B
ARTERIOSCL THROM VAS. 2009;29(12):2117-24.

Tissue factor procoagulant activity of plasma microparticles is increased in patients with early-stage prostate cancer.
Haubold K, Rink M, Spath B, Friedrich M, Chun F, Marx G, Amirkhosravi A, Francis J, Bokemeyer C, Eifrig B, Langer F
THROMB HAEMOSTASIS. 2009;101(6):1147-1155.

TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer.
Helms M, Kemming D, Contag C, Pospisil H, Bartkowiak K, Wang A, Chang S, Buerger H, Brandt B
CANCER RES. 2009;69(12):5049-5056.

CEACAM1+ myeloid cells control angiogenesis in inflammation.
Horst A, Bickert T, Brewig N, Ludewig P, van Rooijen N, Schumacher U, Beauchemin N, Ito W, Fleischer B, Wagener C, Ritter U
BLOOD. 2009;113(26):6726-6736.

Bitter sweetness of complexity
Horst A, Wagener C
TOPICS CURR CHEM. 2009;288:1-15.

Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization.
Joshua A, Reeck K, Langer A, Streichert T, Quitterer U
BIOCHEM BIOPH RES CO. 2009;387(1):186-190.

ASTD: The Alternative Splicing and Transcript Diversity database.
Koscielny G, Vincent L, Gopalakrishnan C, Kumanduri V, Riethoven J, Nardone F, Stanley E, Fallsehr C, Hofmann O, Kull M, Harrington E, Boué S, Eyras E, Plass M, Lopez F, Ritchie W, Moucadel V, Ara T, Pospisil H, Herrmann A, Jens G, Guigó R, Bork P, Doeberitz M, Vilo J, Hide W, Apweiler R, Thanaraj T, Gautheret D
GENOMICS. 2009;93(3):213-220.

Dementia and leukoencephalopathy due to lymphomatosis cerebri
Lewerenz J, Ding X, Matschke J, Schnabel C, Emami P, von Borczyskowski D, Buchert R, Krieger T, de Wit M, Münchau A
BMJ CASE REP. 2009;2009:.

Wound-induced apoplastic peroxidase activities: their roles in the production and detoxification of reactive oxygen species.
Minibayeva F, Kolesnikov O, Chasov A, Beckett R, Lüthje S, Vylegzhanina N, Buck F, Böttger M
PLANT CELL ENVIRON. 2009;32(5):497-508.

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo
Müller F, Mutch N, Schenk W, Smith S, Esterl L, Spronk H, Schmidbauer S, Gahl W, Morrissey J, Renné T
CELL. 2009;139(6):1143-56.

Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study.
Ostad M, Eggeling S, Tschentscher P, Schwedhelm E, Böger R, Wenzel P, Meinertz T, Munzel T, Warnholtz A
ATHEROSCLEROSIS. 2009;205(1):227-232.

Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients.
Priemel M, von Domarus C, Klatte T, Kessler S, Schlie J, Meier S, Proksch N, Pastor F, Netter C, Streichert T, Püschel K, Amling M
J BONE MINER RES. 2009.

Factor XI deficiency in animal models
Renné T, Oschatz C, Seifert S, Müller F, Antovic J, Karlman M, Benz P
J THROMB HAEMOST. 2009;7 Suppl 1:79-83.

DC-SIGN and SRCL bind glycans of carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1): recombinant human glycan-binding receptors as analytical tools.
Samsen A, Bogoevska V, Klampe B, Bamberger A, Lucka L, Horst A, Nollau P, Wagener C
EUR J CELL BIOL. 2009.

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.
Schinke T, Schilling A, Baranowsky A, Seitz S, Marshall R, Linn T, Bläker M, Huebner A, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil F, Andrea D, Frattini A, Streichert T, Püschel K, Villa A, Debatin K, Rueger J, Teti A, Zustin J, Sauter G, Amling M
NAT MED. 2009;15(6):674-681.

Finding one's way in proteomics: a protein species nomenclature.
Schlüter H, Apweiler R, Holzhütter H, Jungblut P
CHEM CENT J. 2009;3:11.

TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.
Schultze A, Decker S, Wellbrock J, Horst A, Vohwinkel G, Schuch G, Bokemeyer C, Loges S, Fiedler W
INVEST NEW DRUG. 2009.

Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism.
Schulze J, Albers J, Baranowsky A, Keller J, Spiro A, Streichert T, Zustin J, Amling M, Schinke T
BONE. 2009.

Statistical quality assessment and outlier detection for liquid chromatography-mass spectrometry experiments.
Schulz-Trieglaff O, Machtejevas E, Reinert K, Schlüter H, Thiemann J, Unger K
BIODATA MIN. 2009;2(1):4.

CEACAM1 expression in pancreatic endocrine tumors.
Serra S, Asa S, Bamberger A, Wagener C, Chetty R
APPL IMMUNOHISTO M M. 2009;17(4):286-293.

Expression of CEACAM-1 in pulmonary adenocarcinomas and their metastases.
Thoem I, Schult-Kronefeld O, Burkholder I, Schuch G, Andritzky B, Kastendieck H, Edler L, Wagener C, Bokemeyer C, Schumacher U, Laack H
ANTICANCER RES. 2009;29(1):249-254.

Bone health and fracture rate in individuals with neurofibromatosis 1 (NF1).
Tucker T, Schnabel C, Hartmann M, Friedrich R, Frieling I, Kruse H, Mautner V, Friedman J
J MED GENET. 2009;46(4):259-265.

Dual role of collagen in factor XII-dependent thrombus formation
van der Meijden P, Munnix I, Auger J, Govers-Riemslag J, Cosemans J, Kuijpers M, Spronk H, Watson S, Renné T, Heemskerk J
BLOOD. 2009;114(4):881-90.

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.
Vockel M, Liew C, Glassmeier G, Brandner J, Fernandez-Ballester G, Schwarz J, Schulz S, Buck F, Serrano L, Richter D, Kreienkamp H
FEBS LETT. 2009;583(1):49-54.

Prostate specific antigen: one out of five disulfide bridges determines inactivation by reduction.
Weber W, Buck F, Meyer A, Hilz H
BIOCHEM BIOPH RES CO. 2009;379(4):1101-1106.

Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function
Wojciak-Stothard B, Torondel B, Zhao L, Renné T, Leiper J
MOL BIOL CELL. 2009;20(1):33-42.

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage M, Ruosaari S, Eijk P, Kaifi J, Hollmén J, Yekebas E, Izbicki J, Brakenhoff R, Streichert T, Riethdorf S, Glatzel M, Ylstra B, Pantel K, Wikman H
CLIN CANCER RES. 2009;15(5):1566-1574.

Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.
Xu E, Dubois M, Leung N, Charbonneau A, Claire T, Avramoglu R, DeMarte L, Elchebly M, Streichert T, Lévy E, Beauchemin N, Marette A
ENDOCRINOLOGY. 2009;150(8):3503-3512.

Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes
Benz P, Blume C, Moebius J, Oschatz C, Schuh K, Sickmann A, Walter U, Feller S, Renné T
J CELL BIOL. 2008;180(1):205-19.

Prostaglandin-induced VASP phosphorylation controls alpha II-spectrin breakdown in apoptotic cells
Benz P, Feller S, Sickmann A, Walter U, Renné T
INT IMMUNOPHARMACOL. 2008;8(2):319-24.

Diadenosine polyphosphates Ap3A and Ap4A, but not Ap5A or Ap6A, induce proliferation of vascular smooth muscle cells.
Bobbert P, Schlüter H, Schultheiss H, Reusch H
BIOCHEM PHARMACOL. 2008;75(10):1966-1973.

B56beta, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching.
Brandt N, Franke K, Johannes S, Buck F, Harder S, Hassel B, Nitsch R, Schumacher S
FASEB J. 2008;22(7):2521-2533.

SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA.
Duning K, Buck F, Barnekow A, Kremerskothen J
J NEUROCHEM. 2008;105(2):351-359.

The whereabouts of transmembrane proteins from rat brain synaptosomes during two-dimensional gel electrophoresis
Eravci M, Fuxius S, Broedel O, Weist S, Krause E, Stephanowitz H, Schlüter H, Eravci S, Baumgartner A
PROTEOMICS. 2008;8(9):1762-1770.

Isolation, crystallization and preliminary X-ray diffraction analysis of L-amino-acid oxidase from Vipera ammodytes ammodytes venom.
Georgieva D, Kardas A, Buck F, Perbandt M, Betzel C
ACTA CRYSTALLOGR F. 2008;64(10):918-921.

Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis.
Georgieva D, Risch M, Kardas A, Buck F, von Bergen M, Betzel C
J PROTEOME RES. 2008;7(3):866-886.

Comparative proteome, transcriptome, and genome analysis of a gonadal and an extragonadal germ cell tumor cell line.
Glaesener S, Honecker F, Veltman I, Gillis A, Rohlfing T, Streichert T, Otto B, Brümmendorf T, Looijenga L, Bokemeyer C, Balabanov S
J PROTEOME RES. 2008;7(9):3890-3899.

Transmission of oxLDL-derived lipid peroxide radicals into membranes of vascular cells is the main inducer of oxLDL-mediated oxidative stress
Hansen-Hagge T, Baumeister E, Bauer T, Schmiedeke D, Renné T, Wanner C, Galle J
ATHEROSCLEROSIS. 2008;197(2):602-11.

The role of calcitonin and alpha-calcitonin gene-related peptide in bone formation.
Hübner A, Keller J, Catalá-Lehnen P, Perkovic S, Streichert T, Emeson R, Amling M, Schinke T
ARCH BIOCHEM BIOPHYS. 2008;473(2):210-217.

The speciation of the proteome.
Jungblut P, Holzhütter H, Apweiler R, Schlüter H
CHEM CENT J. 2008;2:16.

Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke
Kleinschnitz C, Austinat M, Bader M, Renné T, Stoll G
HYPERTENSION. 2008;51(5):e41; author reply e42-3.

Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis
Kleinschnitz C, Braeuninger S, Pham M, Austinat M, Nölte I, Renné T, Nieswandt B, Bendszus M, Stoll G
STROKE. 2008;39(4):1262-8.

Differential phosphoproteome profiling reveals a functional role for VASP in Helicobacter pylori-induced cytoskeleton turnover in gastric epithelial cells
Knauer O, Binai N, Carra G, Beckhaus T, Hanschmann K, Renné T, Backert S, Karas M, Wessler S
CELL MICROBIOL. 2008;10(11):2285-96.

Tissue factor procoagulant activity of plasma microparticles in patients with cancer-associated disseminated intravascular coagulation.
Langer F, Spath B, Haubold K, Holstein K, Marx G, Wierecky J, Brümmendorf T, Dierlamm J, Bokemeyer C, Eifrig B
ANN HEMATOL. 2008;87(6):451-457.

Membrane-bound class III peroxidases: identification, biochemical properties and sequence analysis of isoenzymes purified from maize (Zea mays L.) roots.
Mika A, Buck F, Lüthje S
J PROTEOMICS. 2008;71(4):412-424.

Role of Fra-2 in breast cancer: influence on tumor cell invasion and motility.
Milde-Langosch K, Janke S, Wagner I, Schröder C, Streichert T, Bamberger A, Jänicke F, Löning T
BREAST CANCER RES TR. 2008;107(3):337-347.

Novel roles for factor XII-driven plasma contact activation system
Müller F, Renné T
CURR OPIN HEMATOL. 2008;15(5):516-21.

Insulin inhibition of platelet-endothelial interaction is mediated by insulin effects on endothelial cells without direct effects on platelets
Rauchfuss S, Geiger J, Walter U, Renne T, Gambaryan S
J THROMB HAEMOST. 2008;6(5):856-64.

Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function
Rentsendorj O, Mirzapoiazova T, Adyshev D, Servinsky L, Renné T, Verin A, Pearse D
AM J PHYSIOL-LUNG C. 2008;294(4):L686-97.

Improvement of vascular function by acute and chronic treatment with the PDE-5 inhibitor sildenafil in experimental diabetes mellitus
Schäfer A, Fraccarollo D, Pförtsch S, Flierl U, Vogt C, Pfrang J, Kobsar A, Renné T, Eigenthaler M, Ertl G, Bauersachs J
BRIT J PHARMACOL. 2008;153(5):886-93.

The protein tyrosine phosphatase Rptpzeta is expressed in differentiated osteoblasts and affects bone formation in mice.
Schinke T, Gebauer M, Schilling A, Lamprianou S, Priemel M, Mueldner C, Erdmann C, Streichert T, Ignatius A, Harroch S, Amling M
BONE. 2008;42(3):524-534.

Mass spectrometry for monitoring protease reactions
Schlüter H, Hildebrand D, Gallin C, Schulz A, Thiemann J, Trusch M
ANAL BIOANAL CHEM. 2008;392(5):783-792.

Acceptance of telemonitoring to enhance medication compliance in patients with chronic heart failure
Schmidt S, Sheikzadeh S, Beil B, Patten M, Stettin J
TELEMED E-HEALTH. 2008;14(5):426-33.

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
Varga-Szabo D, Braun A, Kleinschnitz C, Bender M, Pleines I, Pham M, Renné T, Stoll G, Nieswandt B
J EXP MED. 2008;205(7):1583-91.

Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent
Welker P, Böhlick A, Mutig K, Salanova M, Kahl T, Schlüter H, Blottner D, Ponce-Coria J, Gamba G, Bachmann S
AM J PHYSIOL-RENAL. 2008;295(3):789-802.

Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.
Zafrakas M, Tarlatzis B, Streichert T, Pournaropoulos F, Wölfle U, Smeets S, Wittek B, Grimbizis G, Brakenhoff R, Pantel K, Bontis J, Günes C
INT J MOL MED. 2008;21(3):335-344.

Integrated analysis of the cerebrospinal fluid peptidome and proteome.
Zougman A, Pilch B, Podtelejnikov A, Kiehntopf M, Schnabel C, Kumar C, Mann M
J PROTEOME RES. 2008;7(1):386-399.

AMP-activated protein kinase impairs endothelial actin cytoskeleton assembly by phosphorylating vasodilator-stimulated phosphoprotein
Blume C, Benz P, Walter U, Ha J, Kemp B, Renné T
J BIOL CHEM. 2007;282(7):4601-12.

DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues.
Bogoevska V, Nollau P, Lucka L, Grunow D, Klampe B, Uotila L, Samsen A, Gahmberg C, Wagener C
GLYCOBIOLOGY. 2007;17(3):324-333.

Tandem exploitation of Helix pomatia glycosyltransferases: facile syntheses of H-antigen-bearing oligosaccharides.
Bretting H, Buck F, Jacobs G, Meinke S, Scheppokat A, Thiem J
CHEM-EUR J. 2007;13(25):7144-7152.

Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility
Burkard N, Rokita A, Kaufmann S, Hallhuber M, Wu R, Hu K, Hofmann U, Bonz A, Frantz S, Cartwright E, Neyses L, Maier L, Maier S, Renné T, Schuh K, Ritter O
CIRC RES. 2007;100(3):e32-44.

Interaction of brain somatostatin receptors with the PDZ domains of PSD-95.
Christenn M, Kindler S, Schulz S, Buck F, Richter D, Kreienkamp H
FEBS LETT. 2007;581(27):5173-5177.

Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases.
Dahl A, Berlin A, Brunner G, Schulze H, Moll I, Pfüller U, Wagener C, Schachner M, Altevogt P, Schumacher U
CANCER LETT. 2007;248(1):68-80.

Improved comparative proteome analysis based on two-dimensional gel electrophoresis
Eravci M, Fuxius S, Broedel O, Weist S, Eravci S, Mansmann U, Schluter H, Tiemann J, Baumgartner A
PROTEOMICS. 2007;7(4):513-523.

Ena/VASP proteins mediate repulsion from ephrin ligands
Evans I, Renne T, Gertler F, Nobes C
J CELL SCI. 2007;120(Pt 2):289-98.

Novel cell death program leads to neutrophil extracellular traps
Fuchs T, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, Weinrauch Y, Brinkmann V, Zychlinsky A
J CELL BIOL. 2007;176(2):231-41.

Intrinsic pathway of coagulation and arterial thrombosis
Gailani D, Renné T
ARTERIOSCL THROM VAS. 2007;27(12):2507-13.

The intrinsic pathway of coagulation a target for treating thromboembolic disease?
Gailani D, Renné T
J THROMB HAEMOST. 2007;5(6):1106-12.

Mass-spectrometric identification of a novel angiotensin peptide in human plasma
Jankowski V, Vanholder R, van der Giet M, Tölle M, Karadogan S, Gobom J, Furkert J, Oksche A, Krause E, Tran T, Tepel M, Schuchardt M, Schlüter H, Wiedon A, Beyermann M, Bader M, Todiras M, Zidek W, Jankowski J
ARTERIOSCL THROM VAS. 2007;27(2):297-302.

Limitations in molecular detection of lymph node micrometastasis from colorectal cancer.
Klebig F, Fischer C, Petri S, Gerull H, Wagener C, Tschentscher P
DIAGN MOL PATHOL. 2007;16(2):91-95.

Prion protein regulates glutamate-dependent lactate transport of astrocytes.
Kleene R, Loers G, Langer J, Frobert Y, Buck F, Schachner M
J NEUROSCI. 2007;27(45):12331-12340.

Aprotinin-associated hemolytic thrombotic microangiopathy in a patient with acute myelogenous leukemia (AML) and systemic coagulopathy.
Langer F, Steinmetz O, Marx G, Amirkhosravi A, Eifrig B, Bokemeyer C, Brümmendorf T
AM J HEMATOL. 2007;82(12):1122-1124.

Dementia and leukoencephalopathy due to lymphomatosis cerebri.
Lewerenz J, Ding X, Matschke J, Schnabel C, Emami P, von Borczyskowski D, Buchert R, Krieger T, De Wit M, Münchau A
J NEUROL NEUROSUR PS. 2007;78(7):777-778.

Modulation of lamellipodial structure and dynamics by NO-dependent phosphorylation of VASP Ser239
Lindsay S, Ramsey S, Aitchison M, Renné T, Evans T
J CELL SCI. 2007;120(Pt 17):3011-21.

CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases.
Liu W, Wei W, Winer D, Bamberger A, Bamberger C, Wagener C, Ezzat S, Asa S
ONCOGENE. 2007;26(19):2747-2758.

Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery.
Maas R, Dentz L, Schwedhelm E, Thoms W, Kuß O, Hiltmeyer N, Haddad M, Klöss T, Standl T, Böger R
CRIT CARE MED. 2007;35(8):1876-1881.

High-throughput phosphotyrosine profiling using SH2 domains.
Machida K, Thompson C, Dierck K, Jablonowski K, Kärkkäinen S, Liu B, Zhang H, Nash P, Newman D, Nollau P, Pawson T, Renkema G, Saksela K, Schiller M, Shin D, Mayer B
MOL CELL. 2007;26(6):899-915.

Chronic granulomatous disease (CGD) and complete myeloperoxidase deficiency both yield strongly reduced dihydrorhodamine 123 test signals but can be easily discerned in routine testing for CGD
Mauch L, Lun A, O'Gorman M, Harris J, Schulze I, Zychlinsky A, Fuchs T, Oelschlägel U, Brenner S, Kutter D, Rösen-Wolff A, Roesler J
CLIN CHEM. 2007;53(5):890-6.

CEACAM1/VEGF cross-talk during neuroblastic tumour differentiation.
Poliani P, Mitola S, Ravanini M, Ferrari-Toninelli G, D'Ippolito C, Notarangelo L, Bercich L, Wagener C, Memo M, Presta M, Facchetti F
J PATHOL. 2007;211(5):541-549.

Role of Factor XII in hemostasis and thrombosis: clinical implications
Renné T, Gailani D
EXPERT REV CARDIOVAS. 2007;5(4):733-41.

Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function.
Rudolph V, Rudolph T, Hennings J, Blankenberg S, Schnabel R, Steven D, Haddad M, Knittel K, Wende S, Wenzel J, Münzel T, Heitzer T, Meinertz T, Hübner C, Baldus S
FREE RADICAL BIO MED. 2007;43(8):1189-1196.

Mass spectrometry-assisted protease substrate screening
Schlüter H, Rykl J, Thiemann J, Kurzawski S, Gobom J, Tepel M, Zidek W, Linscheid M
ANAL CHEM. 2007;79(3):1251-5.

FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.
Schrepfer S, Deuse T, Koch Nolte F, Krieger T, Haddad M, Schäfer H, Pelletier M, Robbins R, Reichenspurner H
J HEART LUNG TRANSPL. 2007;26(1):70-77.

Effect of inhaled tacrolimus on cellular and humoral rejection to prevent posttransplant obliterative airway disease.
Schrepfer S, Deuse T, Reichenspurner H, Hoffmann J, Haddad M, Fink J, Fischbein M, Robbins R, Pelletier M
AM J TRANSPLANT. 2007;7(7):1733-1742.

Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
Schrepfer S, Deuse T, Sultan K, Haddad M, Böger R, Münzel T, Schäfer H, Pelletier M, Robbins R, Reichenspurner H
CARDIOLOGY. 2007;108(2):128-137.

Antihypertensive therapy induces compartment-specific chemokine expression and a Th1 immune response in the clipped kidney of Goldblatt hypertensive rats.
Steinmetz O, Sadaghiani S, Panzer U, Krebs C, Meyer-Schwesinger C, Streichert T, Fehr S, Hamming I, van Goor H, Stahl R, Wenzel U
AM J PHYSIOL-RENAL. 2007;292(2):876-887.

3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.
Stellmer F, Keyser B, Burckhardt B, Koepsell H, Streichert T, Glatzel M, Jabs S, Thiem J, Herdering W, Koeller D, Goodman S, Lukacs Z, Ullrich K, Burckhardt G, Braulke T, Mühlhausen C
J MOL MED. 2007;85(7):763-770.

AT1-receptor blockade with irbesartan improves peripheral but not coronary endothelial dysfunction in patients with stable coronary artery disease.
Warnholtz A, Ostad M, Heitzer T, Thuneke F, Fröhlich M, Tschentscher P, Schwedhelm E, Böger R, Meinertz T, Munzel T
ATHEROSCLEROSIS. 2007;194(2):439-445.

Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation.
Wong Y, Schulze C, Streichert T, Gronostajski R, Schachner M, Tilling T
GENOME BIOL. 2007;8(5):72.

N-Terminal pro-brain natriuretic peptide: normal ranges in the pediatric population including method comparison and interlaboratory variability.
Albers S, Mir T, Haddad M, Läer S
CLIN CHEM LAB MED. 2006;44(1):80-85.

Patients with solid tumors treated with high-temperature whole body hyperthermia show a redistribution of naive/memory T-cell subtypes.
Atanackovic D, Pollok K, Faltz C, Boeters I, Jung R, Nierhaus A, Braumann K, Hossfeld D, Hegewisch-Becker S
AM J PHYSIOL-REG I. 2006;290(3):585-594.

Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Baldus S, Rudolph V, Roiss M, Ito W, Rudolph T, Eiserich J, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner H, Meinertz T, Heitzer T
CIRCULATION. 2006;113(15):1871-1878.

Stimulation of CEACAM1 expression by 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophore A23187 in endometrial carcinoma cells.
Bamberger A, Briese J, Götze J, Erdmann I, Schulte H, Wagener C, Nollau P
CARCINOGENESIS. 2006;27(3):483-490.

Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulation.
Bamberger A, Minas V, Kalantaridou S, Jessica R, Sadeghian H, Löning T, Charalampopoulos I, Brümmer J, Wagener C, Bamberger C, Schulte H, Chrousos G, Makrigiannakis A
AM J PATHOL. 2006;168(1):141-150.

CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via Lewis x residues.
Bogoevska V, Horst A, Klampe B, Lucka L, Wagener C, Nollau P
GLYCOBIOLOGY. 2006;16(3):197-209.

Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Bosnar M, Bago R, Gall-Troselj K, Streichert T, Paveli J
MOL CARCINOGEN. 2006;45(8):627-633.

Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III
Cichon S, Martin L, Hennies H, Müller F, Van Driessche K, Karpushova A, Stevens W, Colombo R, Renné T, Drouet C, Bork K, Nöthen M
AM J HUM GENET. 2006;79(6):1098-104.

Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.
Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schäfer H, Detter C, Reichenspurner H
TRANSPL INT. 2006;19(4):310-318.

Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.
Dierck K, Machida K, Voigt A, Thimm J, Horstmann M, Fiedler W, Mayer B, Nollau P
NAT METHODS. 2006;3(9):737-744.

Genes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity.
Graefe S, Streichert T, Budde B, Nürnberg P, Steeg C, Müller-Myhsok B, Fleischer B
PLOS ONE. 2006;1:57.

Characterization and expression of CT45 in Hodgkin's lymphoma.
Heidebrecht H, Claviez A, Kruse M, Pollmann M, Buck F, Harder S, Tiemann M, Dörffel W, Parwaresch R
CLIN CANCER RES. 2006;12(16):4804-4811.

Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.
Heitzer T, Rudolph V, Schwedhelm E, Karstens M, Sydow K, Ortak M, Tschentscher P, Meinertz T, Böger R, Baldus S
ARTERIOSCL THROM VAS. 2006;26(7):1648-1652.

Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo.
Horst A, Ito W, Dabelstein J, Schumacher U, Sander H, Claire T, Brümmer J, Meinertz T, Beauchemin N, Wagener C
J CLIN INVEST. 2006;116(6):1596-1605.

Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma
Johne J, Blume C, Benz P, Pozgajová M, Ullrich M, Schuh K, Nieswandt B, Walter U, Renné T
BIOL CHEM. 2006;387(2):173-8.

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer H, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T
J EXP MED. 2006;203(3):513-8.

Complications of non-compaction of the left ventricular myocardium in a paediatric population: a prospective study.
Lilje C, Rázek V, Joyce J, Rau T, Finckh B, Weiss F, Habermann C, Rice J, Weil J
EUR HEART J. 2006;27(15):1855-1860.

Endogenous coenzyme A glutathione disulfide in human myocardial tissue
Luo J, Jankowski V, Henning L, Schlüter H, Zidek W, Jankowski J
J ENDOCRINOL INVEST. 2006;29(8):688-93.

Human EML4, a novel member of the EMAP family, is essential for microtubule formation.
Pollmann M, Parwaresch R, Adam-Klages S, Kruse M, Buck F, Heidebrecht H
EXP CELL RES. 2006;312(17):3241-3251.

The intrinsic pathway of coagulation is essential for thrombus stability in mice
Renné T, Nieswandt B, Gailani D
BLOOD CELL MOL DIS. 2006;36(2):148-51.

Renal cathepsin G and angiotensin II generation
Rykl J, Thiemann J, Kurzawski S, Pohl T, Gobom J, Zidek W, Schlüter H
J HYPERTENS. 2006;24(9):1797-807.

Asymmetric dimethylarginine is an independent risk factor for coronary heart disease: results from the multicenter Coronary Artery Risk Determination investigating the Influence of ADMA Concentration (CARDIAC) study.
Schulze F, Lenzen H, Hanefeld C, Bartling A, Osterziel K, Goudeva L, Schmidt-Lucke C, Kusus M, Maas R, Schwedhelm E, Strödter D, Simon B, Mügge A, Daniel W, Tillmanns H, Maisch B, Streichert T, Böger R
AM HEART J. 2006;152(3):1-8.

Lymphoblastoid cell lines differing in p53 status show clear differences in basal gene expression with minor changes after irradiation.
Zschenker O, Borgmann K, Streichert T, Meier I, Wrona A, Dikomey E
RADIOTHER ONCOL. 2006;80(2):236-249.

Gene disruption of Spred-2 causes dwarfism
Bundschu K, Knobeloch K, Ullrich M, Schinke T, Amling M, Engelhardt C, Renné T, Walter U, Schuh K
J BIOL CHEM. 2005;280(31):28572-80.

Up-regulation of the T cell quiescence factor KLF2 in a leukaemic T-cell line after expression of the inositol 5'-phosphatase SHIP-1.
García-Palma L, Horn S, Haag F, Diessenbacher P, Streichert T, Mayr G, Jücker M
BRIT J HAEMATOL. 2005;131(5):628-631.

Vasodilator-stimulated phosphoprotein-deficient mice demonstrate increased platelet activation but improved renal endothelial preservation and regeneration in passive nephrotoxic nephritis
Hohenstein B, Kasperek L, Kobelt D, Daniel C, Gambaryan S, Renné T, Walter U, Amann K, Hugo C
J AM SOC NEPHROL. 2005;16(4):986-96.

Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor
Jankowski V, Tölle M, Vanholder R, Schönfelder G, van der Giet M, Henning L, Schlüter H, Paul M, Zidek W, Jankowski J
NAT MED. 2005;11(2):223-7.

Isolation and quantification of dinucleoside polyphosphates by using monolithic reversed phase chromatography columns
Jankowski V, Vanholder R, Henning L, Karadogan S, Zidek W, Schlüter H, Jankowski J
J CHROMATOGR B. 2005;819(1):131-9.

Detection of angiotensin II in supernatants of stimulated mononuclear leukocytes by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass analysis
Jankowski V, Vanholder R, van der Giet M, Henning L, Tölle M, Schönfelder G, Krakow A, Karadogan S, Gustavsson N, Gobom J, Webb J, Lehrach H, Giebing G, Schlüter H, Hilgers K, Zidek W, Jankowski J
HYPERTENSION. 2005;46(3):591-7.

Plasma concentrations of N-terminal brain natriuretic peptide in healthy children, adolescents, and young adults: effect of age and gender.
Mir T, Flato M, Falkenberg J, Haddad M, Budden R, Weil J, Albers S, Laer S
PEDIATR CARDIOL. 2005;27(1):73-77.

Serial monitoring of interleukin-1beta, soluble interleukin-2 receptor and lipopolysaccharide binding protein levels after death A comparative evaluation of potential postmortem markers of sepsis.
Reichelt U, Jung R, Nierhaus A, Tsokos M
INT J LEGAL MED. 2005;119(2):80-87.

Defective thrombus formation in mice lacking coagulation factor XII
Renné T, Pozgajová M, Grüner S, Schuh K, Pauer H, Burfeind P, Gailani D, Nieswandt B
J EXP MED. 2005;202(2):271-81.

Local bradykinin formation is controlled by glycosaminoglycans
Renné T, Schuh K, Müller-Esterl W
J IMMUNOL. 2005;175(5):3377-85.

Increased bone formation in mice lacking apolipoprotein E.
Schilling A, Schinke T, Münch C, Gebauer M, Niemeier A, Priemel M, Streichert T, Rueger J, Amling M
J BONE MINER RES. 2005;20(2):274-282.

Salivary cortisol measurement--a reliable method for the diagnosis of Cushing's syndrome.
Trilck M, Flitsch J, Lüdecke D, Jung R, Petersenn S
EXP CLIN ENDOCR DIAB. 2005;113(4):225-230.

A homocysteine metabolism-related dietary pattern and the risk of coronary heart disease in two independent German study populations
Weikert C, Hoffmann K, Dierkes J, Zyriax B, Klipstein-Grobusch K, Schulze M, Jung R, Windler E, Boeing H
J NUTR. 2005;135(8):1981-8.

CEACAM1 enhances invasion and migration of melanocytic and melanoma cells.
Ebrahimnejad A, Streichert T, Nollau P, Horst A, Wagener C, Bamberger A, Brümmer J
AM J PATHOL. 2004;165(5):1781-1787.

Expression and subcellular localization of Spred proteins in mouse and human tissues
Engelhardt C, Bundschu K, Messerschmitt M, Renné T, Walter U, Reinhard M, Schuh K
HISTOCHEM CELL BIOL. 2004;122(6):527-38.

CEA-Related CAMs
Horst A, Wagener C
Handb Exp Pharmacol. 2004;(165):283-341.

Analysis of the releasable nucleotides of platelets
Jankowski J, Henning L, Schlüter H
Methods Mol Biol. 2004;272:97-108.

Endogenous diadenosine tetraphosphate, diadenosine pentaphosphate, and diadenosine hexaphosphate in human myocardial tissue
Luo J, Jankowski V, Güngär N, Neumann J, Schmitz W, Zidek W, Schlüter H, Jankowski J
HYPERTENSION. 2004;43(5):1055-9.

Identification of antigenic proteins of a Theileria species pathogenic for small ruminants in China recognized by antisera of infected animals.
Miranda J, Stumme B, Beyer D, Cruz H, Oliva A, Bakheit M, Wicklein D, Yin H, Lou J, Ahmed J, Seitzer U
ANN NY ACAD SCI. 2004;1026:161-164.

Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo
Pauer H, Renné T, Hemmerlein B, Legler T, Fritzlar S, Adham I, Müller-Esterl W, Emons G, Sancken U, Engel W, Burfeind P
THROMB HAEMOSTASIS. 2004;92(3):503-8.

Nucleic acids from intact epithelial cells as a target for stool-based molecular diagnosis of colorectal cancer.
Spethmann S, Fischer C, Wagener C, Streichert T, Tschentscher P
INT J MOL MED. 2004;13(3):451-454.

Principle and applications of the protein-purification-parameter screening system
Thiemann J, Jankowski J, Rykl J, Kurzawski S, Pohl T, Wittmann-Liebold B, Schlüter H
J CHROMATOGR A. 2004;1043(1):73-80.

Carbohydrate moieties can induce mediator release: a detailed characterization of two major timothy grass pollen allergens.
Wicklein D, Lindner B, Moll H, Kolarich D, Altmann F, Becker W, Petersen A
BIOL CHEM. 2004;385(5):397-407.

Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus
Yoon M, Jankowski V, Montag S, Zidek W, Henning L, Schlüter H, Tepel M, Jankowski J
BIOCHEM BIOPH RES CO. 2004;323(2):377-81.

Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles
Heiss A, DuChesne A, Denecke B, Grötzinger J, Yamamoto K, Renné T, Jahnen-Dechent W
J BIOL CHEM. 2003;278(15):13333-41.

Identification of dinucleoside polyphosphates by matrix-assisted laser desorption/ionisation post-source decay mass spectrometry
Jankowski J, Grosse-Hüttmann P, Zidek W, Schlüter H
RAPID COMMUN MASS SP. 2003;17(11):1189-94.

Identification and quantification of diadenosine polyphosphate concentrations in human plasma
Jankowski J, Jankowski V, Laufer U, van der Giet M, Henning L, Tepel M, Zidek W, Schlüter H
ARTERIOSCL THROM VAS. 2003;23(7):1231-8.

Identification of dinucleoside polyphosphates in adrenal glands
Jankowski J, Jankowski V, Seibt B, Henning L, Zidek W, Schlüter H
BIOCHEM BIOPH RES CO. 2003;304(2):365-70.

The AN69 hemofiltration membrane has a decreasing effect on the intracellular diadenosine pentaphosphate concentration of platelets
Jankowski J, Schlüter H, Henning L, van der Giet M, Jankowski V, Zidek W, Tepel M
KIDNEY BLOOD PRESS R. 2003;26(1):50-4.

Increased plasma phenylacetic acid in patients with end-stage renal failure inhibits iNOS expression
Jankowski J, van der Giet M, Jankowski V, Schmidt S, Hemeier M, Mahn B, Giebing G, Tolle M, Luftmann H, Schluter H, Zidek W, Tepel M
J CLIN INVEST. 2003;112(2):256-64.

Severe phenotype despite high residual glutaryl-CoA dehydrogenase activity: a novel mutation in a Turkish patient with glutaric aciduria type I.
Mühlhausen C, Christensen E, Schwartz M, Muschol N, Ullrich K, Lukacs Z
J INHERIT METAB DIS. 2003;26(7):713-714.

Reversal of immunoparalysis by recombinant human granulocyte-macrophage colony-stimulating factor in patients with severe sepsis.
Nierhaus A, Montag B, Timmler N, Frings D, Gutensohn K, Jung R, Schneider C, Pothmann W, Brassel A, Jochen S
INTENS CARE MED. 2003;29(4):646-651.

Detection of protease activities with the mass-spectrometry-assisted enzyme-screening (MES) system
Schlüter H, Jankowski J, Rykl J, Thiemann J, Belgardt S, Zidek W, Wittmann B, Pohl T
ANAL BIOANAL CHEM. 2003;377(7-8):1102-7.

Identification and characterization of adenosine 5'-tetraphosphate in human myocardial tissue
Westhoff T, Jankowski J, Schmidt S, Luo J, Giebing G, Schlüter H, Tepel M, Zidek W, van der Giet M
J BIOL CHEM. 2003;278(20):17735-40.

Recurrent deep-vein thrombosis based on homozygous factor V Leiden mutation acquired after liver transplantation.
Willems M, Sterneck M, Langer F, Jung R, Haddad M, Hagel C, Kuetemeier R, Eifrig B, Broering D, Fischer L, Rogiers X
LIVER TRANSPLANT. 2003;9(8):870-873.

["Multimedia symposium wares". An enrichment of medical and graduate education?]
Gawad K, Mehrabi A, Streichert T, Jahnke C, Schwarzer H, Izbicki J, Kallinowski F
CHIRURG. 2002;73(5):508-513.

Cytotoxic T lymphocyte mediated recognition of human pancreatic cancer cells.
Peiper M, Sato T, Streichert T, Eisenberger C, Knoefel W, Izbicki J
INT J CANCER. 2002;99(1):88-92.

Diagnosis of growth hormone deficiency in adults by testing with GHRP-6 alone or in combination with GHRH: comparison with the insulin tolerance test.
Petersenn S, Jung R, Beil F
EUR J ENDOCRINOL. 2002;146(5):667-672.

Characterization of the H-kininogen-binding site on factor XI: a comparison of factor XI and plasma prekallikrein
Renné T, Gailani D, Meijers J, Müller-Esterl W
J BIOL CHEM. 2002;277(7):4892-9.

Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2
Renné T, Sugiyama A, Gailani D, Jahnen-Dechent W, Walter U, Müller-Esterl W
INT IMMUNOPHARMACOL. 2002;2(13-14):1867-73.

Effects of dinucleoside polyphosphates on regulation of coronary vascular tone
van der Giet M, Schmidt S, Tölle M, Jankowski J, Schlüter H, Zidek W, Tepel M
EUR J PHARMACOL. 2002;448(2-3):207-13.

Selective agonism of group I P2X receptors by dinucleotides dependent on a single adenine moiety
Cinkilic O, King B, van der Giet M, Schlüter H, Zidek W, Burnstock G
J PHARMACOL EXP THER. 2001;299(1):131-6.

Binding inhibition of type 1 fimbriae to human granulocytes: a flow cytometric inhibition assay using trivalent cluster mannosides.
Horst A, Kötter S, Lindhorst T, Ludwig A, Brandt E, Wagener C
MED MICROBIOL IMMUN. 2001;190(3):145-149.

Dinucleotides as growth-promoting extracellular mediators. Presence of dinucleoside diphosphates Ap2A, Ap2G, and Gp2G in releasable granules of platelets
Jankowski J, Hagemann J, Tepel M, van Der Giet M, Stephan N, Henning L, Gouni-Berthold I, Sachinidis A, Zidek W, Schluter H, Gouni-Berthold H
J BIOL CHEM. 2001;276(12):8904-9.

Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates
Jankowski J, Hagemann J, Yoon M, van der Giet M, Stephan N, Zidek W, Schlüter H, Tepel M
KIDNEY INT. 2001;59(3):1134-41.

Mass-spectrometry-linked screening of protein fractions for enzymatic activities--a tool for functional genomics
Jankowski J, Stephan N, Knobloch M, Fischer S, Schmaltz D, Zidek W, Schlüter H
ANAL BIOCHEM. 2001;290(2):324-9.

Characterization of p-hydroxy-hippuric acid as an inhibitor of Ca2+-ATPase in end-stage renal failure
Jankowski J, Tepel M, Stephan N, van der Giet M, Breden V, Zidek W, Schlüter H
Kidney international. Supplement. 2001;78:S84-8.

Vasoactive diadenosine polyphosphates in human placenta: possible candidates in the pathophysiology of pre-eclampsia?
Jankowski J, Yoon M, Stephan N, Zidek W, Schlüter H
J HYPERTENS. 2001;19(3 Pt 2):567-73.

Detection of micrometastasis through tissue-specific gene expression: its promise and problems.
Jung R, Soondrum K, Krüger W, Neumaier M
Recent Results Cancer Res. 2001;158:32-39.

Donor lymphocyte infusion enhances remission status in patients with persistent disease after allografting for multiple myeloma.
Kröger N, Krüger W, Renges H, Zabelina T, Stute N, Jung R, Wittkowsky G, Kuse R, Zander A
BRIT J HAEMATOL. 2001;112(2):421-423.

Interference of cytokeratin-20 and mammaglobin-reverse-transcriptase polymerase chain assays designed for the detection of disseminated cancer cells.
Krüger W, Jung R, Detlefsen B, Mumme S, Badbaran A, Brandner J, Renges H, Kröger N, Zander A
MED ONCOL. 2001;18(1):33-38.

Disseminated breast cancer cells prior to and after high-dose therapy.
Krüger W, Kröger N, Tögel F, Renges H, Badbaran A, Hornung R, Jung R, Gutensohn K, Gieseking F, Jänicke F, Zander A
J HEMATOTH STEM CELL. 2001;10(5):681-689.

Structure-activity relationships of diadenosine polyphosphates (Ap(n)As), adenosine polyphospho guanosines (Ap(n)Gs) and guanosine polyphospho guanosines (Gp(n)Gs) at P2 receptors in the rat mesenteric arterial bed
Ralevic V, Jankowski J, Schlüter H
BRIT J PHARMACOL. 2001;134(5):1073-83.

Cell surface-associated chondroitin sulfate proteoglycans bind contact phase factor H-kininogen
Renné T, Müller-Esterl W
FEBS LETT. 2001;500(1-2):36-40.

The microbial receptor CEACAM3 is linked to the calprotectin complex in granulocytes.
Streichert T, Ebrahimnejad A, Ganzer S, Flayeh R, Wagener C, Brümmer J
BIOCHEM BIOPH RES CO. 2001;289(1):191-197.

Interleukin-6 and C-reactive protein serum levels in sepsis-related fatalities during the early postmortem period.
Tsokos M, Reichelt U, Jung R, Nierhaus A, Püschel K
FORENSIC SCI INT. 2001;119(1):47-56.

CoenzymeA glutathione disulfide is a potent modulator of angiotensin II-induced vasoconstriction
van der Giet M, Schmid A, Jankowski J, Schlüter H, Zidek W, Tepel M
AM J HYPERTENS. 2001;14(2):164-8.

The critical role of adenosine and guanosine in the affinity of dinucleoside polyphosphates to P(2X)-receptors in the isolated perfused rat kidney
van der Giet M, Westhoff T, Cinkilic O, Jankowski J, Schlüter H, Zidek W, Tepel M
BRIT J PHARMACOL. 2001;132(2):467-74.

Expression of leukemia inhibitory factor (LIF) and LIF receptor (LIF-R) in the human adrenal cortex: implications for steroidogenesis.
Bamberger A, Schulte H, Wullbrand A, Jung R, Beil F, Bamberger C
MOL CELL ENDOCRINOL. 2000;162(1-2):145-149.

CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor.
Ergün S, Kilik N, Ziegeler G, Hansen A, Nollau P, Götze J, Wurmbach J, Horst A, Weil J, Fernando M, Wagener C
MOL CELL. 2000;5(2):311-320.

Isolation and characterization of coenzyme A glutathione disulfide as a parathyroid-derived vasoconstrictive factor
Jankowski J, Schröter A, Tepel M, van der Giet M, Stephan N, Luo J, Zidek W, Schlüter H
CIRCULATION. 2000;102(20):2548-52.

Quantitative PCR.
Jung R, Soondrum K, Neumaier M
CLIN CHEM LAB MED. 2000;38(9):833-836.

Expression of human milk fat globulin proteins in cells of haemopoietic origin.
Krüger W, Lohner R, Jung R, Kröger N, Zander A
BRIT J CANCER. 2000;83(7):874-879.

Effects of diadenosine polyphosphates (Ap(n)As) and adenosine polyphospho guanosines (Ap(n)Gs) on rat mesenteric artery P2X receptor ion channels
Lewis C, Gitterman D, Schlüter H, Evans R
BRIT J PHARMACOL. 2000;129(1):124-30.

High molecular weight kininogen utilizes heparan sulfate proteoglycans for accumulation on endothelial cells
Renné T, Dedio J, David G, Müller-Esterl W
J BIOL CHEM. 2000;275(43):33688-96.

Subcellular targeting of multiligand-binding protein gC1qR
Dedio J, Renné T, Weisser M, Müller-Esterl W
IMMUNOPHARMACOLOGY. 1999;45(1-3):1-5.

High-performance liquid chromatographic assay of the diadenosine polyphosphates in human platelets
Jankowski J, Potthoff W, van der Giet M, Tepel M, Zidek W, Schlüter H
ANAL BIOCHEM. 1999;269(1):72-8.

Identification and characterization of P(1), P(7)-Di(adenosine-5')-heptaphosphate from human platelets
Jankowski J, Tepel M, van der Giet M, Tente I, Henning L, Junker R, Zidek W, Schlüter H
J BIOL CHEM. 1999;274(34):23926-31.

Age effects on interleukin-6 and interleukin-1beta responses to endurance exercise in patients with neuromuscular diseases.
Joerg Stuerenburg H, Jung R, Schoser B
ARCH GERONTOL GERIAT. 1999;29(1):21-27.

Detection of micrometastasis by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes.
Jung R, Petersen K, Krüger W, Wolf M, Wagener C, Zander A, Neumaier M
BRIT J CANCER. 1999;81(5):870-873.

Inositol-1,4,5-trisphosphate increase by diadenosine tetraphosphate in preparations from failing human myocardium
Knapp J, Bokník P, Linck B, Läer S, Müller F, Neumann J, Vahlensieck U, Schlüter H, Zidek W, Schmitz W
N-S ARCH PHARMACOL. 1999;360(3):354-7.

Identification and characterization of diadenosine 5',5"'-P1,P2 -diphosphate and diadenosine 5',5"'-P1,P3-triphosphate in human myocardial tissue
Luo J, Jankowski J, Knobloch M, Van der Giet M, Gardanis K, Russ T, Vahlensieck U, Neumann J, Schmitz W, Tepel M, Deng M, Zidek W, Schlüter H
FASEB J. 1999;13(6):695-705.

Identification of diadenosine hexaphosphate in human erythrocytes
Luo J, Jankowski J, Tepel M, von Der Giet M, Zidek W, Schlüter H
HYPERTENSION. 1999;34(4 Pt 2):872-5.

Inotropic effects of diadenosine tetraphosphate in isolated canine cardiac preparations
Neumann J, Meissner A, Bokník P, Gombosová I, Knapp J, Lüss H, Müller F, Schlüter H, Zidek W, Rolf N, Van Aken H, Vahlensieck U, Schmitz W
J CARDIOVASC PHARM. 1999;33(1):151-6.

Mapping of the discontinuous H-kininogen binding site of plasma prekallikrein. Evidence for a critical role of apple domain-2
Renné T, Dedio J, Meijers J, Chung D, Müller-Esterl W
J BIOL CHEM. 1999;274(36):25777-84.

Age effects on growth hormone and testosterone responses to endurance exercise in patients with neuromuscular diseases.
Stuerenburg H, Jung R, Kunze K
ARCH GERONTOL GERIAT. 1999;28(1):45-51.

Effect of dexamethasone on the lymphocytic Na+/H+ antiporter activity
Tepel M, Pytlik M, van der Giet M, Schlüter H, Jankowski J, Zidek W
J HYPERTENS. 1999;17(11):1553-6.

Inotropic effects of diadenosine tetraphosphate (AP4A) in human and animal cardiac preparations
Vahlensieck U, Bokník P, Gombosová I, Huke S, Knapp J, Linck B, Lüss H, Müller F, Neumann J, Deng M, Scheld H, Jankowski H, Schlüter H, Zidek W, Zimmermann N, Schmitz W
J PHARMACOL EXP THER. 1999;288(2):805-13.

Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney
van der Giet M, Cinkilic O, Jankowski J, Tepel M, Zidek W, Schlüter H
BRIT J PHARMACOL. 1999;127(6):1463-9.

Diadenosine polyphosphates in cultured vascular smooth-muscle cells and endothelium cells--their interaction with specific receptors and their degradation
Verspohl E, Johannwille B, Kaiserling-Buddemeier I, Schlüter H, Hagemann J
J PHARM PHARMACOL. 1999;51(10):1175-81.

Non-receptor-mediated activation of IK(ATP) and inhibition of IK(ACh) by diadenosine polyphosphates in guinea-pig atrial myocytes
Brandts B, Brandts A, Wellner-Kienitz M, Zidek W, Schluter H, Pott L
J PHYSIOL-LONDON. 1998;512 ( Pt 2):407-20.

Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ ATPase in end-stage renal failure
Jankowski J, Luftmann H, Tepel M, Leibfritz D, Zidek W, Schlüter H
J AM SOC NEPHROL. 1998;9(7):1249-57.

Identification of oxidized low-density lipoprotein in human serum by NMR spectroscopy
Jankowski J, Nofer J, Tepel M, Griewel B, Schlüter H, Assmann G, Zidek W
CLIN SCI. 1998;95(4):489-95.

Purification of chemically synthesised dinucleoside(5',5') polyphosphates by displacement chromatography
Jankowski J, Potthoff W, Zidek W, Schlüter H
Journal of chromatography. B, Biomedical sciences and applications. 1998;719(1-2):63-70.

Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro.
Jung R, Krüger W, Hosch S, Holweg M, Kröger N, Gutensohn K, Wagener C, Neumaier M, Zander A
BRIT J CANCER. 1998;78(9):1194-1198.

Molecular co-operation between protein PAM and streptokinase for plasmin acquisition by Streptococcus pyogenes
Ringdahl U, Svensson M, Wistedt A, Renné T, Kellner R, Müller-Esterl W, Sjöbring U
J BIOL CHEM. 1998;273(11):6424-30.

Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets
Schlüter H, Grobeta I, Bachmann J, Kaufmann R, van der Giet M, Tepel M, Nofer J, Assmann G, Karas M, Jankowski J, Zidek W
J CLIN INVEST. 1998;101(3):682-8.

Mediation of the vasoactive properties of diadenosine tetraphosphate via various purinoceptors
van der Giet M, Jankowski J, Schlüter H, Zidek W, Tepel M
J HYPERTENS. 1998;16(12 Pt 2):1939-43.

Absorption of kininogen from human plasma by Streptococcus pyogenes is followed by the release of bradykinin
Ben Nasr A, Herwald H, Sjöbring U, Renné T, Müller-Esterl W, Björck L
BIOCHEM J. 1997;326 ( Pt 3):657-60.

Infusion of hydrophilic bile salts protects the liver from reperfusion injury in the rat.
Hertl M, Clausnitzer N, Rogiers X, Jung R, Broelsch C
TRANSPL P. 1997;29(1-2):386-387.

Donor pretreatment with hydrophilic bile salts protects the liver from preservation and reperfusion injury in the rat.
Hertl M, Engelhard O, Vollmers B, Rogiers X, Jung R, Broelsch C
TRANSPL P. 1997;29(1-2):388-389.

Effect of diadenosine polyphosphates on Ca2+ ATPase activity
Jankowski J, Schlüter H, Tepel M, Spieker C, Zidek W
J MOL MED. 1997;75(9):674-7.

Quality management and influential factors for the detection of single metastatic cancer cells by reverse transcriptase polymerase chain reaction.
Jung R, Ahmad-Nejad P, Wimmer M, Gerhard M, Wagener C, Neumaier M
Eur J Clin Chem Clin Biochem. 1997;35(1):3-10.

Reversal of RT-PCR inhibition observed in heparinized clinical specimens.
Jung R, Lübcke C, Wagener C, Neumaier M
BIOTECHNIQUES. 1997;23(1):24, 26, 28.

Identification of endogenous Des-Arg9-[Hyp3]-bradykinin in human plasma with post-source-decay matrix-assisted laser desorption/ionization mass spectrometry
Schlüter H, Mentrup D, Gross I, Meyer H, Spengler B, Kaufmann R, Zidek W
ANAL BIOCHEM. 1997;246(1):15-9.

Diadenosine polyphosphates' action on calcium and vessel contraction
Tepel M, Jankowski J, Schlüter H, Bachmann J, van der Giet M, Ruess C, Terliesner J, Zidek W
AM J HYPERTENS. 1997;10(12 Pt 1):1404-10.

Differential effects of diadenosine phosphates on purinoceptors in the rat isolated perfused kidney
van der Giet M, Khattab M, Börgel J, Schlüter H, Zidek W
BRIT J PHARMACOL. 1997;120(8):1453-60.

Demonstration of p53 protein and TP53 gene mutations in oligodendrogliomas
Hagel C, Laking G, Laas R, Scheil S, Jung R, Milde-Langosch K, Stavrou D
EUR J CANCER. 1996;32A(13):2242-2248.

Mapping of the discontinuous kininogen binding site of prekallikrein. A distal binding segment is located in the heavy chain domain A4
Herwald H, Renné T, Meijers J, Chung D, Page J, Colman R, Müller-Esterl W
J BIOL CHEM. 1996;271(22):13061-7.

Effects of diadenosine polyphosphates on renal function and blood pressure in anesthetized Wistar rats
Hohage H, Reinhardt C, Borucki U, Enck G, Schlüter H, Schlatter E, Zidek W
J AM SOC NEPHROL. 1996;7(8):1216-22.

Reverse transcriptase/polymerase chain reaction detection of cytokeratin-19 mRNA in bone marrow and blood of breast cancer patients.
Krüger W, Krzizanowski C, Holweg M, Stockschläder M, Kröger N, Jung R, Mross K, Jonat W, Zander A
J CANCER RES CLIN. 1996;122(11):679-686.

Vascular actions of diadenosine phosphates
Schlüter H, Tepel M, Zidek W
J Auton Pharmacol. 1996;16(6):357-62.

Diadenosine polyphosphates increase cytosolic calcium and attenuate angiotensin-II-induced changes of calcium in vascular smooth muscle cells
Tepel M, Bachmann J, Schlüter H, Zidek W
J VASC RES. 1996;33(2):132-8.

Diadenosine polyphosphates induce transplasma membrane calcium influx in cultured glomerular mesangial cells
Tepel M, Heidenreich S, Schlüter H, Beinlich A, Nofer J, Walter M, Assmann G, Zidek W
EUR J CLIN INVEST. 1996;26(12):1077-84.

Increased lymphocytic Na+/H+ exchange activity after hemodialysis: evidence for an endogenous inhibitor of Na+/H+ exchange in patients with end-stage renal failure
Tepel M, Klaus T, Laukemper S, Schlüter H, Zidek W
LIFE SCI. 1996;59(18):1545-52.

Diadenosine polyphosphates regulate cytosolic calcium in human fibroblast cells by interaction with P2x purinoceptors coupled to phospholipase C
Tepel M, Löwe S, Nofer J, Assmann G, Schlüter H, Zidek W
Biochim Biophys Acta. 1996;1312(2):145-50.

Negative chronotropic and inotropic effects exerted by diadenosine hexaphosphate (AP6A) via A1-adenosine receptors
Vahlensieck U, Bokník P, Knapp J, Linck B, Müller F, Neumann J, Herzig S, Schlüter H, Zidek W, Deng M, Scheld H, Schmitz W
BRIT J PHARMACOL. 1996;119(5):835-44.

Regulation of rat mesangial cell growth by diadenosine phosphates
Heidenreich S, Tepel M, Schlüter H, Harrach B, Zidek W, Heidenreich S
J CLIN INVEST. 1995;95(6):2862-7.

Effects of diadenosine polyphosphates, ATP and angiotensin II on membrane voltage and membrane conductances of rat mesangial cells
Kleta R, Hirsch J, Heidenreich S, Schlüter H, Zidek W, Schlatter E
PFLUG ARCH EUR J PHY. 1995;430(5):713-20.

Tumour diagnosis by PCR-based detection of tumour cells.
Nollau P, Jung R, Neumaier M, Wagener C
Scand J Clin Lab Invest Suppl. 1995;221:116-121.

Coenzyme A glutathione disulfide. A potent vasoconstrictor derived from the adrenal gland
Schlüter H, Meissner M, van der Giet M, Tepel M, Bachmann J, Gross I, Nordhoff E, Karas M, Spieker C, Witzel H
CIRC RES. 1995;76(4):675-80.

Diadenosine polyphosphate-induced increase in cytosolic free calcium in vascular smooth muscle cells
Tepel M, Bachmann J, Schluter H, Zidek W
J HYPERTENS. 1995;13(12 Pt 2):1686-8.

Diadenosine phosphates and the physiological control of blood pressure
Schlüter H, Offers E, Brüggemann G, van der Giet M, Tepel M, Nordhoff E, Karas M, Spieker C, Witzel H, Zidek W
NATURE. 1994;367(6459):186-8.

Cellular Ca2+ ATPase activity in diabetes mellitus
Spieker C, Fischer S, Zierden E, Schlüter H, Tepel M, Zidek W
HORM METAB RES. 1994;26(11):544-7.

Partial purification and characterization of a circulating hypertensive factor in spontaneously hypertensive rats
Schlüter H, Kluth B, Börjesson-Stoll R, Nordhoff E, Zidek W
EUR J BIOCHEM. 1993;218(1):67-73.

Rapid screening for Tp53 mutations by temperature gradient gel electrophoresis: a comparison with SSCP analysis.
Scholz R, Milde-Langosch K, Jung R, Schlechte H, Kabisch H, Wagener C, Löning T
HUM MOL GENET. 1993;2(12):2155-2158.

Ca2+ ATPase activity in essential and renal hypertension
Spieker C, Pan N, Schlüter H, Zidek W
CLIN EXP HYPERTENS. 1993;15(1):143-52.

A novel platelet-derived renal vasoconstrictor agent in normotensives and essential hypertensives
Agha A, Schlüter H, König S, Biel K, Tepel M, Zidek W
J VASC RES. 1992;29(3):281-9.

Generation of angiotensin II from human plasma by tissue kallikrein
Krivoy N, Schlüter H, Karas M, Zidek W
CLIN SCI. 1992;83(4):477-82.

Application of cross-flow filtration to the purification of biologically active peptides in human plasma after incubation with a protease-rich extract
Schlüter H, Krivoy N, Hürster A, Ingendoh A, Karas M, Zidek W
J CHROMATOGR A. 1992;625(1):3-11.

A vasopressor factor partially purified from human parathyroid glands
Schlüter H, Quante C, Buchholz B, Dietl K, Spieker C, Karas M, Zidek W
BIOCHEM BIOPH RES CO. 1992;188(1):323-9.

Effect of plasma from patients with essential hypertension on vascular resistance in the isolated perfused rat kidney
Bachmann J, Schlüter H, Storkebaum W, Witzel H, Wessels F, Zidek W
CLIN SCI. 1991;80(1):17-23.

Effect of plasma from essential hypertensives on vascular tone of aortic strips, isolated perfused mesentery and isolated perfused kidney
Bachmann J, Schlüter H, Storkebaum W, Witzel H, Zidek W
LIFE SCI. 1990;47(15):1365-74.

Effect of plasma from essential hypertensives on tension of aortic strips
Zidek W, Bachmann J, Schlüter H, Witzel H, Storkebaum W, Sachinidis A
Clinical and experimental hypertension. Part A, Theory and practice. 1990;12(3):365-81.

Letzte Aktualisierung aus dem FIS: 19.11.2024 - 23:32 Uhr