2023
Testicular germ cell tumour arising 15 years after radiotherapy with 18 Gy for germ cell neoplasia in situ. Dieckmann KP, Tribius S, Angerer M, Salzbrunn A, von Kopylow K, Mollenhauer M, Wülfing C., 03.2023, in: STRAHLENTHER ONKOL. 199, 3, S. 322-326 5 S, DOI: 10.1007/s00066-022-02025-x
Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue. Aden NL, Bleeke M, Kordes U, Brunne B, Holstermann B, Biemann R, Ceglarek U, Soave A, Salzbrunn A, Schneider S, von Kopylow K, 26.01.2023, in: CELLS-BASEL. 12, 3, 415, DOI: 10.3390/cells12030415
2022
Vergleich dreier kommerzieller Kryomedien bezüglich des Einflusses auf die diagnostischen Spermienparameter. Kruschel EL, Laubis K, Hahn G, Steinert S, Salzbrunn A, Schneider S, von Kopylow K, 08.09.2022, in: J Reprodmed Endokrinol. 2022, 19 (Supplementum 3), S. 7
2021
Vergleich von 3 Organkulturbedingungen für adultes Hodengewebe hinsichtlich der Testosteronproduktion, Zellerhalt und IL-6-Sekretion.
Aden NL, Salzbrunn A, Schneider SW, von Kopylow K, J Reprodmed Endokrinol. 2021;18(5):249
2020
Ex vivo testis explant culture of human intrapubertal testicular tissue.
Aden N, Soave A, Kordes U, Bleeke M, Salzbrunn A, von Kopylow K, J Reprodmed Endokrinol. 2020;14(1):39 - 40
2019
The DNA methylation profile of human spermatogonia at single-cell- and single-allele-resolution refutes its role in spermatogonial stem cell function and germ cell differentiation.
Fend-Guella D, von Kopylow K, Spiess A, Schulze W, Salzbrunn A, Diederich S, El Hajj N, Haaf T, Zechner U, Linke M, MOL HUM REPROD. 2019;25(6):283-294
Expression of miRNA-371a-3p in seminal plasma and ejaculate is associated with sperm concentration.
Radtke A, Dieckmann K, Grobelny F, Salzbrunn A, Oing C, Schulze W, Belge G, ANDROLOGY-US. 2019;7(4):469-474
2018
Dynamics, ultrastructure and gene expression of human in-vitro organized testis cells from testicular sperm extraction biopsies.
von Kopylow K, Schulze W, Salzbrunn A, Schaks M, Schäfer E, Roth B, Schlatt S, Spiess A
MOL HUM REPROD. 2018;24(3):123-134
Methylation profiling of human Spermatogonial Stem Cells (HSSCs) at single allele resolution.
Fend D, von Kopylow K, Schulze W, Salzbrunn A, Spiess AN, El Hajj N, Haaf T, Zechner U, Linke M, MED GENET-BERLIN. 2018;30(1):135
Das DNA-Methylierungsprofil humaner, aus TESE-Biopsien isolierter Spermatogonien auf Einzelzell- bzw. Einzel-Allel-Ebene.
von Kopylow K, Fend D, Spiess A, Schulze W, Salzbrunn A, Diederich S, El Hajj N, Haaf T, Zechner U, Linke M, J Reprodmed Endokrinol. 2018;15(Supplementum 1):2-3
In-vitro-Reorganisation adulter humaner Hodenzellen in TESE-Biopsien im dreischichtigen 3D-Gradientensystem.
von Kopylow K, Schulze W, Salzbrunn A, Alves-Lopes J, Stukenborg J, Spiess A, J Reprodmed Endokrinol. 2018;15(Supplementum 1):3
2017
Human spermatogonial markers.
von Kopylow K, Spiess A, STEM CELL RES. 2017;25:300-309, DOI: 10.1016/j.scr.2017.11.011
Zelluläre Komposition, Ultrastruktur, Genexpression und Dynamik humaner in vitro-reorganisierter adulter Hodenzellen.
von Kopylow K, Schulze W, Salzbrunn A, Schaks M, Schäfer E, Schlatt S, Roth B, Spiess A,
J Reprodmed Endokrinol. 2017;14(5):233 - 234
2016
Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries.
Damsgaard J, Joensen U, Carlsen E, Erenpreiss J, Blomberg Jensen M, Matulevicius V, Zilaitiene B, Olesen I, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen H, Juul A, Skakkebæk N, Jørgensen N, EUR UROL. 2016;70(6):1019-1029
Compensated reduction in Leydig cell function is associated with lower semen quality variables: a study of 8182 European young men.
Jørgensen N, Joensen U, Toppari J, Punab M, Erenpreiss J, Zilaitiene B, Paasch U, Salzbrunn A, Fernandez M, Virtanen H, Matulevicius V, Olea N, Jensen T, Petersen J, Skakkebæk N, Andersson A, HUM REPROD. 2016;31(5):947-57
Comment on "Absence of sperm RNA elements correlates with idiopathic male infertility".
Cappallo-Obermann H, Spiess A, SCI TRANSL MED. 2016;8(353):353tc1
Reorganisation testikulärer Strukturen bei In-vitro-kultivierten Zellen aus dem humanen adulten normogonadotropen Hoden mit vollständiger Spermatogenese.
von Kopylow K, Schlatt S, Schulze W, Salzbrunn A, Spiess A, J Reprodmed Endokrinol. 2016;13(4):151
Isolation and gene expression analysis of single potential human spermatogonial stem cells.
von Kopylow K, Schulze W, Salzbrunn A, Spiess A, MOL HUM REPROD. 2016;22(4):229-39
2014
Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA.
Jensen T, Swan S, Jørgensen N, Toppari J, Redmon B, Punab M, Drobnis E, Haugen T, Zilaitiene B, Sparks A, Irvine D, Wang C, Jouannet P, Brazil C, Paasch U, Salzbrunn A, Skakkebæk N, Andersson A, HUM REPROD. 2014;29(8):1801-9
Einzelzellmarkierung und -isolierung potenzieller humaner spermatogonialer Stammzellen.
von Kopylow K, Spiess A, Schulze W, J Reprodmed Endokrinol. 2014;11(4):189
Visual selection of human potential spermatogonial stem cells by bead-tagging.
von Kopylow K, Spiess A, Schulze W, 2014. 18th ETW European Testis Workshop. IV-41
2013
Fold-change correction values for testicular somatic transcripts in gene expression studies of human spermatogenesis.
Cappallo-Obermann H, Feig C, Schulze W, Spiess A, HUM REPROD. 2013;28(3):590-598, DOI: 10.1093/humrep/des433
The sperm protamine mRNA ratio as a clinical parameter to estimate the fertilizing potential of men taking part in an ART programme.
Rogenhofer N, Dansranjavin T, Schorsch M, Spiess A, Wang H, von Schönfeldt V, Cappallo-Obermann H, Baukloh V, Yang H, Paradowska A, Chen B, Thaler C, Weidner W, Schuppe H, Steger K, HUM REPROD. 2013;28(4):969-78
New Approaches to Diagnosing Male Infertility: Part I: Microarray Analysis of Testicular Biopsy Specimens from Men with Intact and Impaired Spermatogenesis.
Spiess A, Schulze W, 2013. Atlas on the Human Testis. Jezek D (Hrsg.). 1. Aufl. Springer, 253-261
Kolokalisation von FGF9 und FGFR3 in adulten humanen Spermatogonien.
von Kopylow K, Spiess A, Schulze W, Kirchhoff C, J Reprodmed Endokrinol. 2013;10(5-6):330
2012
Fibroblast growth factor receptor 3 is highly expressed in rarely dividing human type A spermatogonia.
von Kopylow K, Staege H, Schulze W, Will H, Kirchhoff C, Histochem Cell Biol. 2012;138(5):759-772, DOI: 10.1007/s00418-012-0991-7
Differential marker protein expression specifies rarefaction zone-containing human A (dark) spermatogonia.
von Kopylow K, Staege H, Spiess A, Schulze W, Will H, Primig M, Kirchhoff C, REPRODUCTION. 2012;143(1):45-57, DOI: 10.1530/REP-11-0290
FGFR3 as a potential marker for human spermatogonial stem cells.
von Kopylow K, Spiess A, Schulze W, Staege H, Will H, Kirchhoff C, J Reprodmed Endokrinol. 2012;9(5):365
2011
Highly purified spermatozoal RNA obtained by a novel method indicates an unusual 28S/18S rRNA ratio and suggests impaired ribosome assembly.
Capallo-Obermann H, Schulze W, Jastrow H, Baukloh V, Spiess A, MOL HUM REPROD. 2011;17(11):669-678
A one-step real-time multiplex PCR for screening Y-chromosomal microdeletions without downstream amplicon size analysis.
Kozina V, Capallo-Obermann H, Gromoll J, Spiess A, PLOS ONE. 2011;6(8):23174
2010
A biopsy sample reduction approach to identify significant alterations of the testicular transcriptome in the presence of Y-chromosomal microdeletions that are independent of germ cell composition.
Cappallo-Obermann H, von Kopylow K, Schulze W, Spiess A, HUM MOL GENET. 2010;128(4):421-31
Screening for biomarkers of spermatogonia within the human testis: a whole genome approach.
von Kopylow K, Kirchhoff C, Jezek D, Schulze W, Feig C, Primig M, Steinkraus V, Spiess A
HUM REPROD. 2010;25(5):1104-1112, DOI: 10.1093/humrep/deq053
2009
Expression of SNURF-SNRPN upstream transcripts and epigenetic regulatory genes during human spermatogenesis.
Wawrzik M, Spiess A, Herrmann R, Buiting K, Horsthemke B, EUR J HUM GENET. 2009
Molekulare Charakterisierung humaner Spermatogonien
von Kopylow K, Kirchhoff C, Schulze W, Spiess A, J Reprodmed Endokrinol. 2009;6(5):225
2008
Semen quality in sub-fertile range for a significant proportion of young men from the general German Population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig.
Paasch U, Salzbrunn A, Glander H, Plambeck K, Salzbrunn H, Grunewald S, Stucke J, Vierula M, Skakkebaek N, Jørgensen N, INT J ANDROL. 2008;31(2):93-102
1996
Pregnancy after intracytoplasmic sperm injection of spermatozoa extracted from frozen-thawed testicular biopsy.
Fischer R, Baukloh V, Naether O, Schulze W, Salzbrunn A, Benson D, HUM REPROD. 1996;11(10):2197-9
A new concept for the extraction of testicular spermatozoa as a tool for assisted fertilization (ICSI).
Salzbrunn A, Benson D, Holstein A, Schulze W, HUM REPROD. 1996;11(4):752-5