- Institutsdirektor
Tätigkeitsschwerpunkte
Publikationen
2019
Inositol hexakisphosphate increases the size of platelet aggregates
Brehm M, Klemm U, Rehbach C, Erdmann N, Kolšek K, Lin H, Aponte-Santamaría C, Gräter F, Rauch B, Riley A, Mayr G, Potter B, Windhorst S
BIOCHEM PHARMACOL. 2019;161:14-25.
A novel 6-pyrophosphorylating IP6 kinase (IP6-6K) discovered in the protozoon Trichomonas vaginalis
Wundenberg T, Nalaskowski M, Löser B, Fanick W, Hackl T, Fürnkranz U, Rehbach C, Lin H, Mayr G
MOL BIOCHEM PARASIT. 2019;227:53-63.
2015
The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells
Schröder D, Tödter K, Gonzalez B, Franco-Echevarría E, Rohaly G, Blechner C, Lin H, Mayr G, Windhorst S
BIOCHEM PHARMACOL. 2015;96(2):143-50.
2014
Discovery of InsP6-kinases as InsP6 dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio
Wundenberg T, Grabinski N, Lin H, Mayr G
BIOCHEM J. 2014.
2013
A non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA
Brehm M, Wundenberg T, Williams J, Mayr G, Shears S
J CELL SCI. 2013;126(Pt 2):437-44.
Expression Regulation of the Metastasis-Promoting Protein InsP3-Kinase-A in Tumor Cells.
Chang L, Schwarzenbach H, Meyer-Staeckling S, Brandt B, Mayr G, Weitzel J, Windhorst S
MOL CANCER RES. 2013.
Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
Helmis C, Blechner C, Lin H, Schweizer M, Mayr G, Nielsen P, Windhorst S
BIOSCIENCE REP. 2013;33(5):.
Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation
Windhorst S, Lin H, Blechner C, Fanick W, Brandt L, Brehm M, Mayr G
BIOCHEM J. 2013;450(1):115-25.
2012
A novel Entamoeba histolytica inositol phosphate kinase catalyzes the formation of 5PP-Ins(1,2,3,4,6)P(5)
Löser B, Nalaskowski M, Fanick W, Lin H, Tannich E, Mayr G
MOL BIOCHEM PARASIT. 2012;181(1):49-52.
Nucleocytoplasmic shuttling of human inositol phosphate multikinase is influenced by CK2 phosphorylation.
Meyer R, Nalaskowski M, Ehm P, Schröder C, Naj X, Brehm M, Mayr G
BIOL CHEM. 2012;393(3):149-160.
A toolkit for graded expression of green fluorescent protein fusion proteins in mammalian cells.
Nalaskowski M, Ehm P, Giehler S, Mayr G
ANAL BIOCHEM. 2012;428(1):24-27.
The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nuclei.
Nalaskowski M, Metzner A, Brehm M, Labiadh S, Brauer H, Grabinski N, Mayr G, Jücker M
CELL SIGNAL. 2012;24(3):621-628.
A Plasmodium multi-domain protein possesses multiple inositol phosphate kinase activities.
Stritzke C, Nalaskowski M, Fanick W, Lin H, Mayr G
MOL BIOCHEM PARASIT. 2012;186(2):134-138.
Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients.
Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, Lin H, Mayr G, Kindler S
CELL SIGNAL. 2012;24(3):750-757.
Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis.
Wundenberg T, Mayr G
BIOL CHEM. 2012;393(9):979-998.
2011
Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.
Nalaskowski M, Fliegert R, Ernst O, Brehm M, Fanick W, Windhorst S, Lin H, Giehler S, Hein J, Lin Y, Mayr G
J BIOL CHEM. 2011;286(6):4500-4510.
Human regulatory T cells rapidly suppress T cell receptor-induced Ca(2+), NF-κB, and NFAT signaling in conventional T cells.
Schmidt A, Oberle N, Weiss E, Vobis D, Frischbutter S, Baumgrass R, Falk C, Haag M, Brügger B, Lin H, Mayr G, Reichardt P, Gunzer M, Suri-Payer E, Krammer P
SCI SIGNAL. 2011;4(204):90.
Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells.
Windhorst S, Kalinina T, Schmid K, Blechner C, Kriebitzsch N, Hinsch R, Chang L, Herich L, Schumacher U, Mayr G
INT J CANCER. 2011;129(6):1300-1309.
2010
Synthesis and nonradioactive micro-analysis of diphosphoinositol phosphates by HPLC with postcolumn complexometry.
Lin H, Lindner K, Mayr G
Methods Mol Biol. 2010;645:103-122.
Inositol-1,4,5-trisphosphate-3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumour cells by two functional activities.
Windhorst S, Fliegert R, Blechner C, Möllmann K, Hosseini Z, Guenther T, Eiben M, Chang L, Lin H, Fanick W, Schumacher U, Brandt B, Mayr G
J BIOL CHEM. 2010;285(8):5541-5554.
2009
Structural analysis and detection of biological inositol pyrophosphates reveals that the VIP/PPIP5K family are 1/3-kinases.
Lin H, Fridy P, Ribeiro A, Choi J, Barma D, Vogel G, Falck J, Shears S, York J, Mayr G
J BIOL CHEM. 2009;284(3):1863-1872.
Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
Metzner A, Precht C, Fehse B, Fiedler W, Stocking C, Günther A, Mayr G, Jücker M
GENE THER. 2009;16(4):570-573.
Phosphoinositide and inositol phosphate analysis in lymphocyte activation.
Sauer K, Huang Y, Lin H, Sandberg M, Mayr G
Curr Protoc Immunol. 2009;11:1.
2008
Chronic lithium salt treatment reduces CRE/CREB-directed gene transcription and reverses its upregulation by chronic psychosocial stress in transgenic reporter gene mice.
Böer U, Cierny I, Krause D, Heinrich A, Lin H, Mayr G, Hiemke C, Knepel W
NEUROPSYCHOPHARMACOL. 2008;33(10):2407-2415.
Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.
Hoxha E, Fehse B, Ortmeyer G, Stocking C, Mayr G, Jücker M
LEUKEMIA LYMPHOMA. 2008;49(6):1206-1208.
Ins(1,4,5)P3 3-kinase-A overexpression induces cytoskeletal reorganization via a kinase-independent mechanism.
Windhorst S, Blechner C, Lin H, Elling C, Nalaskowski M, Kirchberger T, Guse A, Mayr G
BIOCHEM J. 2008;414(3):407-417.
2007
Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase.
Brehm M, Schenk T, Zhou X, Fanick W, Lin H, Windhorst S, Nalaskowski M, Kobras M, Shears S, Mayr G
BIOCHEM J. 2007;408(3):335-345.
Radiosensitization of tumour cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis.
Kasten-Pisula U, Windhorst S, Dahm-Daphi J, Mayr G, Dikomey E
RADIOTHER ONCOL. 2007;83(3):296-303.
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner A, Horstmann M, Fehse B, Ortmeyer G, Niemeyer C, Stocking C, Mayr G, Jücker M
GENE THER. 2007;14(8):699-703.
2006
Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations.
Ehmann F, Horn S, Garcia-Palma L, Wegner W, Fiedler W, Giehl K, Mayr G, Jücker M
LEUKEMIA LYMPHOMA. 2006;47(7):1387-1391.
Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains.
Nalaskowski M, Windhorst S, Stockebrand M, Mayr G
BIOL CHEM. 2006;387(5):583-593.
2005
Up-regulation of the T cell quiescence factor KLF2 in a leukaemic T-cell line after expression of the inositol 5'-phosphatase SHIP-1.
García-Palma L, Horn S, Haag F, Diessenbacher P, Streichert T, Mayr G, Jücker M
BRIT J HAEMATOL. 2005;131(5):628-631.
Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase.
Mayr G, Windhorst S, Hillemeier K
J BIOL CHEM. 2005;280(14):13229-13240.
2004
Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)
Brehm M, Schreiber I, Bertsch U, Wegner A, Mayr G
BIOCHEM J. 2004;382(1):353-362.
Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.
Horn S, Endl E, Fehse B, Weck M, Mayr G, Jücker M
LEUKEMIA. 2004;18(11):1839-1849.
An optimized fixation and extraction technique for high resolution of inositol phosphate signals in rodent brain.
Lorke D, Gustke H, Mayr G
NEUROCHEM RES. 2004;29(10):1887-1896.
The families of kinases removing the Ca2+ releasing second messenger Ins(1,4,5)P3.
Nalaskowski M, Mayr G
CURR MOL MED. 2004;4(3):277-290.
2003
Analysis of subcellular calcium signals in T-lymphocytes.
Kunerth S, Mayr G, Koch-Nolte F, Guse A
CELL SIGNAL. 2003;15(8):783-792.
Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm.
Nalaskowski M, Bertsch U, Fanick W, Stockebrand M, Schmale H, Mayr G
J BIOL CHEM. 2003;278(22):19765-19776.
2002
Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity.
Guse A, Cakir-Kiefer C, Fukuoka M, Shuto S, Weber K, Bailey V, Matsuda A, Mayr G, Oppenheimer N, Schuber F, Potter B
BIOCHEMISTRY-US. 2002;41(21):6744-6751.
The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization.
Nalaskowski M, Deschermeier C, Fanick W, Mayr G
BIOCHEM J. 2002;366(2):549-556.
Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complex.
Schwarzmann N, Kunerth S, Weber K, Mayr G, Guse A
J BIOL CHEM. 2002;277(52):50636-50642.
2001
Transient tyrosine phosphorylation of human ryanodine receptor upon T cell stimulation.
Guse A, Tsygankov A, Weber K, Mayr G
J BIOL CHEM. 2001;276(37):34722-34727.
Mechanisms involved in alpha6beta1-integrin-mediated Ca(2+) signalling.
Schöttelndreier H, Potter B, Mayr G, Guse A
CELL SIGNAL. 2001;13(12):895-899.
Assay for ADP-ribosyl cyclase by reverse-phase high-performance liquid chromatography.
Schweitzer K, Mayr G, Guse A
ANAL BIOCHEM. 2001;299(2):218-226.
Inositol hexakisphosphate increases L-type Ca2+ channel activity by stimulation of adenylyl cyclase.
Yang S, Yu J, Mayr G, Hofmann F, Larsson O, Berggren P
FASEB J. 2001;15(10):1753-1763.
2000
Nicotinic acid adenine dinucleotide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signaling.
Berg I, Potter B, Mayr G, Guse A
J CELL BIOL. 2000;150(3):581-588.
The second messenger binding site of inositol 1,4,5-trisphosphate 3-kinase is centered in the catalytic domain and related to the inositol trisphosphate receptor site.
Bertsch U, Deschermeier C, Fanick W, Girkontaite I, Hillemeier K, Johnen H, Weglöhner W, Emmrich F, Mayr G
J BIOL CHEM. 2000;275(3):1557-1564.
Diphospho-myo-inositol phosphates during the life cycle of Dictyostelium and Polysphondylium.
Laussmann T, Pikzack C, Thiel U, Mayr G, Vogel G
EUR J BIOCHEM. 2000;267(8):2447-2451.
Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase.
Oude Weernink P, Schulte P, Guo Y, Wetzel J, Amano M, Kaibuchi K, Haverland S, Voss M, Schmidt M, Mayr G, Jakobs K
J BIOL CHEM. 2000;275(14):10168-10174.
1999
A novel A-isoform-like inositol 1,4,5-trisphosphate 3-kinase from chicken erythrocytes exhibits alternative splicing and conservation of intron positions between vertebrates and invertebrates.
Bertsch U, Haefs M, Möller M, Deschermeier C, Fanick W, Kitzerow A, Ozaki S, Meyer H, Mayr G
GENE. 1999;228(1-2):61-71.
Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230.
Gehrmann T, Gülkan H, Suer S, Herberg F, Balla A, Vereb G, Mayr G, Heilmeyer L
BBA-BIOMEMBRANES. 1999;1437(3):341-356.
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose.
Guse A, Da Silva C, Berg I, Skapenko A, Weber K, Heyer P, Hohenegger M, Ashamu G, Schulze-Koops H, Potter B, Mayr G
NATURE. 1999;398(6722):70-73.
Pharmacological activation of the ryanodine receptor in Jurkat T-lymphocytes.
Hohenegger M, Berg I, Weigl L, Mayr G, Potter B, Guse A
BRIT J PHARMACOL. 1999;128(6):1235-1240.
Beta1-integrins mediate Ca2+-signalling and T cell spreading via divergent pathways.
Schöttelndreier H, Mayr G, Guse A
CELL SIGNAL. 1999;11(8):611-619.
1998
Quantification of intracellular levels of cyclic ADP-ribose by high-performance liquid chromatography.
Da Silva C, Potter B, Mayr G, Guse A
J CHROMATOGR B. 1998;707(1-2):43-50.
Ectocellular CD38-catalyzed synthesis and intracellular Ca2+-signalling activity of cyclic ADP-ribose in T-lymphocytes are not functionally related.
Da Silva C, Schweitzer K, Heyer P, Malavasi F, Mayr G, Guse A
FEBS LETT. 1998;439(3):291-296.
Enhanced hippocampal CA1 LTP but normal spatial learning in inositol 1,4,5-trisphosphate 3-kinase(A)-deficient mice.
Jun K, Choi G, Yang S, Choi K, Kim H, Chan G, Storm D, Albert C, Mayr G, Lee C, Shin H
LEARN MEMORY. 1998;5(4-5):317-330.
1997
Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells.
Albert C, Safrany S, Bembenek M, Reddy K, Reddy K, Falck J, Bröcker M, Shears S, Mayr G
BIOCHEM J. 1997;327(2):553-560.
Vicinal thiols are involved in inositol 1,2,3,5,6-pentakisphosphate 5-phosphatase activity from fetal calf thymus.
Bandyopadhyay U, Kaiser T, Rudolf M, Schultz C, Guse A, Mayr G
BIOCHEM BIOPH RES CO. 1997;240(1):146-149.
Suppression of thyrotropin receptor-G protein-phospholipase C coupling by activation of protein kinase C in thyroid carcinoma cells.
Broecker M, Mayr G, Derwahl M
ENDOCRINOLOGY. 1997;138(9):3787-3796.
Ca2+ entry induced by cyclic ADP-ribose in intact T-lymphocytes.
Guse A, Berg I, Da Silva C, Potter B, Mayr G
J BIOL CHEM. 1997;272(13):8546-8550.
Ca(2+)-signalling in human T-lymphocytes. Potential roles for cyclic ADP-ribose and 2'-phospho-cyclic ADP-ribose.
Guse A, Da Silva C, Potter B, Mayr G
ADV EXP MED BIOL. 1997;419:431-436.
1-(5-phospho-beta-D-ribosyl)2'-phosphoadenosine 5'-phosphate cyclic anhydride induced Ca2+ release in human T-cell lines.
Guse A, Da Silva C, Weber K, Armah C, Ashamu G, Schulze C, Potter B, Mayr G, Hilz H
EUR J BIOCHEM. 1997;245(2):411-417.
Unique properties of the capacitative Ca(2+)-entry antagonist LU 52396: its inhibitory activity depends on the activation state of the cells.
Guse A, de Wit C, Klokow T, Schweitzer K, Mayr G
CELL CALCIUM. 1997;22(2):91-97.
Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate.
Larsson O, Barker C, Sjöholm A, Carlqvist H, Michell R, Bertorello A, Nilsson T, Honkanen R, Mayr G, Zwiller J, Berggren P
SCIENCE. 1997;278(5337):471-474.
Formation of multinucleated giant cells in vitro is dependent on the stage of monocyte to macrophage maturation.
Möst J, Spötl L, Mayr G, Gasser A, Sarti A, Dierich M
BLOOD. 1997;89(2):662-671.
Integrin-mediated intracellular Ca2+ signaling in Jurkat T lymphocytes.
Weismann M, Guse A, Sorokin L, Bröker B, Frieser M, Hallmann R, Mayr G
J IMMUNOL. 1997;158(4):1618-1627.
1996
Regulation of cADP-ribose-induced Ca2+ release by Mg2+ and inorganic phosphate.
Guse A, Silva C, Weber K, Ashamu G, Potter B, Mayr G
J BIOL CHEM. 1996;271(39):23946-23953.
1995
Inositol phosphate structural requisites for Ca2+ influx.
DeLisle S, Mayr G, Welsh M
AM J PHYSIOL-HEART C. 1995;268(6 Pt 1):1485-1491.
Characterization of cyclic adenosine diphosphate-ribose-induced Ca2+ release in T lymphocyte cell lines.
Guse A, Da Silva C, Emmrich F, Ashamu G, Potter B, Mayr G
J IMMUNOL. 1995;155(7):3353-3359.
Non-radioactive, isomer-specific inositol phosphate mass determinations: high-performance liquid chromatography-micro-metal-dye detection strongly improves speed and sensitivity of analyses from cells and micro-enzyme assays.
Guse A, Goldwich A, Weber K, Mayr G
J Chromatogr B Biomed Appl. 1995;672(2):189-198.
Serine phosphorylation in the NH2 terminus of p53 facilitates transactivation.
Mayr G, Reed M, Wang P, Wang Y, Schweds J, Tegtmeyer P
CANCER RES. 1995;55(11):2410-2417.
Highly cooperative Ca2+ elevations in response to Ins(1,4,5)P3 microperfusion through a patch-clamp pipette.
Schrenzel J, Demaurex N, Foti M, Van Delden C, Jacquet J, Mayr G, Lew D, Krause K
BIOPHYS J. 1995;69(6):2378-2391.
1994
Second messenger specificity of the inositol trisphosphate receptor: reappraisal based on novel inositol phosphates.
DeLisle S, Radenberg T, Wintermantel M, Tietz C, Parys J, Pittet D, Welsh M, Mayr G
AM J PHYSIOL-HEART C. 1994;266(2 Pt 1):429-436.
Role of phospholipase C in Dictyostelium: formation of inositol 1,4,5-trisphosphate and normal development in cells lacking phospholipase C activity.
Drayer [, Kaay V, Mayr G, Haastert V
EMBO J. 1994;13(7):1601-1609.
p53 oligomerization and DNA looping are linked with transcriptional activation.
Stenger J, Tegtmeyer P, Mayr G, Reed M, Wang Y, Wang P, Hough P, Mastrangelo I
EMBO J. 1994;13(24):6011-6020.
1993
Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells.
Schlegel W, Mollard P, Demaurex N, Theler J, Chiavaroli C, Guérineau N, Vacher P, Mayr G, Krause K, Wollheim C
Adv Second Messenger Phosphoprotein Res. 1993;28:143-152.
The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s).
Stephens L, Radenberg T, Thiel U, Vogel G, Khoo K, Dell A, Jackson T, Hawkins P, Mayr G
J BIOL CHEM. 1993;268(6):4009-4015.
1992
Regulation of Ca2+ influx in myeloid cells. Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores.
Demaurex N, Schlegel W, Varnai P, Mayr G, Lew D, Krause K
J CLIN INVEST. 1992;90(3):830-839.
Metabolism of inositol phosphates in the protozoan Paramecium. Characterization of a novel inositol-hexakisphosphate-dephosphorylating enzyme.
Freund W, Mayr G, Tietz C, Schultz J
EUR J BIOCHEM. 1992;207(1):359-367.
Inositol tetrakisphosphate isomers and elevation of cytosolic Ca2+ in vasopressin-stimulated insulin-secreting RINm5F cells.
Li G, Pralong W, Pittet D, Mayr G, Schlegel W, Wollheim C
J BIOL CHEM. 1992;267(7):4349-4356.
1991
Binding of sugar phosphates, inositol phosphates and phosphorylated amino acids to actin.
Gaertner A, Mayr G, Wegner A
EUR J BIOCHEM. 1991;198(1):67-71.
Masses of inositol phosphates in resting and tetanically stimulated vertebrate skeletal muscles.
Mayr G, Thieleczek R
BIOCHEM J. 1991;280(3):631-640.
1990
Relation of phosphatidylinositol metabolism to glycolytic pathway in skeletal muscle membranes.
Heilmeyer L, Han J, Thieleczek R, Varsanyi M, Mayr G
MOL CELL BIOCHEM. 1990;99(2):111-116.
Synthesis and application of photoaffinity analogues of inositol 1,4,5-trisphosphate selectively substituted at the 1-phosphate group.
Schäfer R, Nehls-Sahabandu M, Grabowsky B, Dehlinger-Kremer M, Schulz I, Mayr G
BIOCHEM J. 1990;272(3):817-825.
1989
Inositol 1,4-bisphosphate is an allosteric activator of muscle-type 6-phosphofructo-1-kinase.
Mayr G
BIOCHEM J. 1989;259(2):463-470.
Chemoattractant receptor promotion of Ca2+ influx across the plasma membrane of HL-60 cells. A role for cytosolic free calcium elevations and inositol 1,3,4,5-tetrakisphosphate production.
Pittet D, Lew D, Mayr G, Monod A, Schlegel W
J BIOL CHEM. 1989;264(13):7251-7261.
Mass changes in inositol tetrakis- and pentakisphosphate isomers induced by chemotactic peptide stimulation in HL-60 cells.
Pittet D, Schlegel W, Lew D, Monod A, Mayr G
J BIOL CHEM. 1989;264(31):18489-18493.
The quantitative spectrum of inositol phosphate metabolites in avian erythrocytes, analysed by proton n.m.r. and h.p.l.c. with direct isomer detection.
Radenberg T, Scholz P, Bergmann G, Mayr G
BIOCHEM J. 1989;264(2):323-333.
Inositol polyphosphate-mediated repartitioning of aldolase in skeletal muscle triads and myofibrils.
Thieleczek R, Mayr G, Brandt N
J BIOL CHEM. 1989;264(13):7349-7356.
1988
Semisynthetic derivatives of inositol 1,4,5-trisphosphate substituted at the 1-phosphate group. Effects on calcium release from permeabilized guinea-pig parotid acinar cells and comparison with binding to aldolase A.
Henne V, Mayr G, Grabowski B, Koppitz B, Söling H
EUR J BIOCHEM. 1988;174(1):95-101.
A novel metal-dye detection system permits picomolar-range h.p.l.c. analysis of inositol polyphosphates from non-radioactively labelled cell or tissue specimens.
Mayr G
BIOCHEM J. 1988;254(2):585-591.
1987
Characterization of the calmodulin-binding sites of muscle phosphofructokinase and comparison with known calmodulin-binding domains.
Buschmeier B, Meyer H, Mayr G
J BIOL CHEM. 1987;262(20):9454-9462.
Interaction of calmodulin with phosphofructokinase: binding studies and evaluation of enzymatic and physicochemical changes.
Mayr G
METHOD ENZYMOL. 1987;139:745-763.
The only inositol tetrakisphosphate detectable in avian erythrocytes is the isomer lacking phosphate at position 3: a NMR study.
Mayr G, Dietrich W
FEBS LETT. 1987;213(2):278-282.
N pi-methylhistidine in myosin-light-chain kinase.
Meyer H, Mayr G
Biol Chem Hoppe Seyler. 1987;368(12):1607-1611.
5S-rRNA-containing ribonucleoproteins from rabbit muscle and liver. Complex and partial primary structures.
Nendza R, Digweed M, Meyer H, Erdmann V, Mayr G
EUR J BIOCHEM. 1987;169(1):85-95.
1986
Mammalian aldolases are isomer-selective high-affinity inositol polyphosphate binders.
Koppitz B, Vogel F, Mayr G
EUR J BIOCHEM. 1986;161(2):421-433.
1985
Steady-state kinetics of skeletal muscle myosin light chain kinase indicate a strong down regulation by products.
Geuss U, Mayr G, Heilmeyer L
EUR J BIOCHEM. 1985;153(2):327-334.
1984
Interaction of calmodulin with muscle phosphofructokinase. Changes of the aggregation state, conformation and catalytic activity of the enzyme.
Mayr G
EUR J BIOCHEM. 1984;143(3):513-520.
Interaction of calmodulin with muscle phosphofructokinase. Interplay with metabolic effectors of the enzyme under physiological conditions.
Mayr G
EUR J BIOCHEM. 1984;143(3):521-529.
1983
Phosphofructokinase is a calmodulin binding protein.
Mayr G, Heilmeyer L
FEBS LETT. 1983;159(1-2):51-57.
Shape and substructure of skeletal muscle myosin light chain kinase.
Mayr G, Heilmeyer L
BIOCHEMISTRY-US. 1983;22(18):4316-4326.
Skeletal muscle myosin light chain kinase. A refined structural model.
Mayr G, Heilmeyer L
FEBS LETT. 1983;157(2):225-231.
1978
[Steroid-cardiomyopathy: experimental generation, demonstration and quantification of its hemodynamic and contractile effects]
Strauer B, Beer K, Bürger S, Hübner G, Löhrs U, Mayr G, Meinardus A, Scherpe A
Verh Dtsch Ges Inn Med. 1978;84:679-682.
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