Fluid and burns in children: What we know and what we do not know-a retrospective analysis of the German Burn Registry from 2015 to 2022

EUR J PEDIATR. 2024;183(12):5479-5488.

Time is Gut. Approaching Intestinal Leiomyositis: Case Presentation and Literature Review
Aftzoglou M, Heinrich C, Clauditz T, Menter T, Dorth D, Reinshagen K, Königs I
PEDIATR GASTROENTERO. 2024;27(4):197-205.

Bilateral Diaphragmatic Agenesis in Cornelia de Lange Syndrome
Fritsch L, Reinshagen K, Apostolidou S, Singer D, Peters U, de Sousa M, Herrmann J, Deindl P
Z GEBURTSH NEONATOL. 2024;228(4):394-395.

The Dual Role of Neutrophil Extracellular Traps (NETs) in Sepsis and Ischemia-Reperfusion Injury: Comparative Analysis across Murine Models
Kiwit A, Lu Y, Lenz M, Knopf J, Mohr C, Ledermann Y, Klinke-Petrowsky M, Pagerols Raluy L, Reinshagen K, Herrmann M, Boettcher M, Elrod J
INT J MOL SCI. 2024;25(7):.

NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children
Najem S, Fattouh M, Wintges K, Schoof B, Koerner M, Reinshagen K, Koenigs I
EUR J TRAUMA EMERG S. 2024;50(4):1807-1815.

Non-fracture acute compartment syndrome in the upper extremity of a 14-year-old boy: A case report and review of the literature
Niklaus M, Reinshagen K, Wintges K
INT J SURG CASE REP. 2024;121:109983.

Revisiting Neuroblastoma: Nrf2, NF-κB and Phox2B as a Promising Network in Neuroblastoma
Peggion S, Najem S, Kolman J, Reinshagen K, Pagerols Raluy L
CURR ISSUES MOL BIOL. 2024;46(4):3193-3208.

Exploring cell death mechanisms in spheroid cultures using a novel application of the RIP3-caspase3-assay
Philippi C, Hagens J, Heuer K, Schmidt H, Schuppert P, Pagerols Raluy L, Trochimiuk M, Li Z, Bunders M, Reinshagen K, Tomuschat C
SCI REP-UK. 2024;14(1):16032.

The paediatric polytrauma CT-indication (PePCI)-score-Development of a prognostic model to reduce unnecessary CT scans in paediatric trauma patients
Strahl A, Willemsen J, Schoof B, Reinshagen K, Frosch K, Wintges K
INJURY. 2024;55(5):111494.

Factors Influencing Performance in Laparoscopic Suturing and Knot Tying: A Cohort Study
Armbrust L, Lenz M, Elrod J, Kiwit A, Reinshagen K, Boettcher J, Boettcher M
EUR J PEDIATR SURG. 2023;33(2):144-151.

Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors
Behrendt P, Boettcher M, Zierke K, Najem S, Zapf H, Reinshagen K, Wößmann W, Boettcher J
CHILDREN-BASEL. 2023;10(10):.

Clinical outcome, quality of life, and mental health in long-gap esophageal atresia: comparison of gastric sleeve pull-up and delayed primary anastomosis
Boettcher M, Hauck M, Fuerboeter M, Elrod J, Vincent D, Boettcher J, Reinshagen K
PEDIATR SURG INT. 2023;39(1):166.

Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions
Elrod J, Heuer A, Knopf J, Schoen J, Schönfeld L, Trochimiuk M, Stiel C, Appl B, Raluy L, Saygi C, Zlatar L, Hosari S, Royzman D, Winkler T, Lochnit G, Leppkes M, Grützmann R, Schett G, Tomuschat C, Reinshagen K, Herrmann M, Fuchs T, Boettcher M
ISCIENCE. 2023;26(12):.

Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox
Elrod J, Kiwit A, Lenz M, Rohde H, Börnigen D, Alawi M, Mohr C, Pagerols Raluy L, Trochimiuk M, Knopf J, Reinshagen K, Herrmann M, Boettcher M
CELLS-BASEL. 2023;12(3):.

Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
Elrod J, Lenz M, Kiwit A, Armbrust L, Schönfeld L, Reinshagen K, Pagerols Raluy L, Mohr C, Saygi C, Alawi M, Rohde H, Herrmann M, Boettcher M
FRONT IMMUNOL. 2023;14:1113948.

Surgical Experience Affects the Outcome of Central Venous Access Catheter Implantation in Children: A Retrospective Cohort Study
Fritsch L, Le M, Elrod J, Wössmann W, Vincent D, Reinshagen K, Boettcher M
J PEDIAT HEMATOL ONC. 2023;45(2):57-62.

Appendicitis and Peritonitis in Children with a Ventriculo-Peritoneal Shunt
Fröschle G, Hagens J, Mannweiler P, Groth F, Kammler G, Reinshagen K, Tomuschat C
CHILDREN-BASEL. 2023;10(3):.

CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Jordan-Paiz A, Martrus G, Steinert F, Kaufmann M, Sagebiel A, Schreurs R, Rechtien A, Baumdick M, Jung J, Möller K, Wegner L, Grüttner C, Richert L, Thünauer R, Schroeder-Schwarz J, van Goudoever J, Geijtenbeek T, Altfeld M, Pals S, Perez D, Klarenbeek P, Tomuschat C, Sauter G, Königs I, Schumacher U, Friese M, Melling N, Reinshagen K, Bunders M
CELL MOL IMMUNOL. 2023;20(2):201-213.

Expanded ILC2s in human infant intestines promote tissue growth
Möller K, Wegner L, Malsy J, Baumdick M, Borggrewe M, Jordan-Paiz A, Jung J, Martrus G, Kretschmer P, Sagebiel A, Schreurs R, Hagen S, Burmester G, Clauditz T, Pals S, Boettcher M, Melling N, Sauter G, Tomuschat C, Königs I, Schumacher U, Altfeld M, Bernink J, Perez D, Reinshagen K, Bunders M
MUCOSAL IMMUNOL. 2023;16(4):408-421.

Biliatresone induces cholangiopathy in C57BL/6J neonates
Schmidt H, Hagens J, Schuppert P, Appl B, Raluy L, Trochimiuk M, Philippi C, Li Z, Reinshagen K, Tomuschat C
SCI REP-UK. 2023;13(1):.

Immunofluorescence Imaging of Neutrophil Extracellular Traps in Human and Mouse Tissues
Schoenfeld L, Appl B, Pagerols-Raluy L, Heuer A, Reinshagen K, Boettcher M
JOVE-J VIS EXP. 2023;(198):.

Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate
Schubert J, Wößmann W, Königs I, Clauditz T, Kordes U, Reinshagen K
Z GEBURTSH NEONATOL. 2023;227(3):231-235.

Abdominal Wall Movements Predict Intra-Abdominal Pressure Changes in Rats: A Novel Non-Invasive Intra-Abdominal Pressure Detection Method
Vincent D, Mietzsch S, Braun W, Trochimiuk M, Reinshagen K, Boettcher M
CHILDREN-BASEL. 2023;10(8):.

DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis
Willemsen J, Wenskus J, Lenz M, Rhode H, Trochimiuk M, Appl B, Pagarol-Raluy L, Börnigen D, Bang C, Reinshagen K, Herrmann M, Elrod J, Boettcher M
FRONT IMMUNOL. 2023;14:1254838.

Kigelia africana inhibits proliferation and induces cell death in stage 4 Neuroblastoma cell lines
Ahrens S, Appl B, Trochimiuk M, Dücker C, Feixas Serra G, Oliver Grau A, Reinshagen K, Pagerols Raluy L
BIOMED PHARMACOTHER. 2022;154:.

Pediatric Surgery and Self-Reported Anxiety in Children and their Parents: A Psychometric Analysis of the State-Trait Operation Anxiety (STOA) Questionnaire
Barkmann C, Härter V, Trah J, Reinshagen K
FRONT PEDIATR. 2022;10:987658.

Mental Health of Siblings of Children with Rare Congenital Surgical Diseases during the COVID-19 Pandemic
Boettcher J, Nazarian R, Fuerboeter M, Liedtke A, Wiegand-Grefe S, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2022;32(5):422-428.

Markers of neutrophil activation and extracellular trap formation predict appendicitis
Boettcher M, Schacker A, Esser M, Schönfeld L, Ebenebe C, Rohde H, Mokhaberi N, Trochimiuk M, Appl B, Raluy L, Reinshagen K, Klohs S, Königs I
SURGERY. 2022;171(2):312-319.

Telementoring of Open and Laparoscopic Knot Tying and Suturing Is Possible: A Randomized Controlled Study
Elrod J, Boettcher J, Vincent D, Schwarz D, Trautmann T, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2022;32(5):443-451.

Auswirkungen der Corona Pandemie auf die Notfallversorgung im Kindesalter und die zeitliche Entwicklung im Verlauf der Pandemie
Elrod J, Mahaleh S, Mohr C, Boettcher M, Dietze N, Hübner U, Koch B, Steinbrink A, Harandipour N, Gräfin von Waldersee E, Shahsavari S, Reinshagen K, Königs I
KLIN PADIATR. 2022;234(1):33-41.

Are We Hitting the Target?: The Effectiveness of Distinct Antibiotic Regimens in Pediatric Appendectomies
Elrod J, Yarmal F, Mohr C, Dennebaum M, Boettcher M, Vincent D, Reinshagen K, Koenigs I
PEDIATR INFECT DIS J. 2022;41(6):460-465.

First genome-wide association study of esophageal atresia identifies three genetic risk loci at CTNNA3, FOXF1/FOXC2/FOXL1, and HNF1B
Gehlen J, Giel A, Köllges R, Haas S, Zhang R, Trcka J, Sungur A, Renziehausen F, Bornholdt D, Jung D, Hoyer P, Nordenskjöld A, Tibboel D, Vlot J, Spaander M, Smigiel R, Patkowski D, Roeleveld N, van Rooij I, de Blaauw I, Hölscher A, Pauly M, Leutner A, Fuchs J, Niethammer J, Melissari M, Jenetzky E, Zwink N, Thiele H, Hilger A, Hess T, Trautmann J, Marks M, Baumgarten M, Bläss G, Landén M, Fundin B, Bulik C, Pennimpede T, Ludwig M, Ludwig K, Mangold E, Heilmann-Heimbach S, Moebus S, Herrmann B, Alsabeah K, Burgos C, Lilja H, Azodi S, Stenström P, Arnbjörnsson E, Frybova B, Lebensztejn D, Debek W, Kolodziejczyk E, Kozera K, Kierkus J, Kaliciński P, Stefanowicz M, Socha-Banasiak A, Kolejwa M, Piaseczna-Piotrowska A, Czkwianianc E, Nöthen M, Grote P, Rygl M, Reinshagen K, Spychalski N, Ludwikowski B, Hubertus J, Heydweiller A, Ure B, Muensterer O, Aubert O, Gosemann J, Lacher M, Degenhardt P, Boemers T, Mokrowiecka A, Małecka-Panas E, Wöhr M, Knapp M, Seitz G, de Klein A, Oracz G, Brosens E, Reutter H, Schumacher J
HUM GENET GENOM ADV. 2022;3(2):.

Prevalence of Hirschsprung-associated enterocolitis in patients with Hirschsprung disease
Hagens J, Reinshagen K, Tomuschat C
PEDIATR SURG INT. 2022;38(1):3-24.

The Epidemiology behind Pectus Excavatum: Clinical Study and Review of the Literature
Kloth K, Klohs S, Bhullar J, Boettcher M, Hempel M, Trah J, Reinshagen K
EUR J PEDIATR SURG. 2022;32(4):316-320.

NET Release of Long-Term Surviving Neutrophils
Kolman J, Pagerols Raluy L, Müller I, Nikolaev V, Trochimiuk M, Appl B, Wadehn H, Dücker C, Stoll F, Boettcher M, Reinshagen K, Trah J
FRONT IMMUNOL. 2022;13:815412.

Operative Volume of Newborn Surgery in German University Hospitals: High Volume Versus Low Volume Centers
Lacher M, Barthlen W, Eckoldt F, Fitze G, Fuchs J, Hosie S, Kaiser M, Meyer T, Muensterer O, Reinshagen K, Rothe K, Seitz G, Stuhldreier G, Troebs R, Ure B, von Schweinitz D, Wessel L, Wünsch L, Rolle U
EUR J PEDIATR SURG. 2022;32(5):391-398.

The Spaced Learning Concept in Combination With Halsted and Peyton - A Randomized Controlled Study
Le M, Boettcher J, Vincent D, Elrod J, Mietzsch S, Romero P, Perez A, Reinshagen K, Boettcher M
J SURG EDUC. 2022;79(5):1228-1236.

Laparoscopic Subtotal Splenectomy in Children and Adolescents With Spherocytosis
Le M, Grosse R, Elrod J, Klinke M, Reinshagen K, Boettcher M
DTSCH ARZTEBL INT. 2022;119(49):848-849.

Systematic review: The quality of life of patients with biliary atresia
Le M, Reinshagen K, Tomuschat C
J PEDIATR SURG. 2022;57(12):934-946.

CfDNA and DNases: New Biomarkers of Sepsis in Preterm Neonates—A Pilot Study
Lenz M, Maiberger T, Armbrust L, Kiwit A, Von der Wense A, Reinshagen K, Elrod J, Boettcher M
CELLS-BASEL. 2022;11(2):.

Should the processus vaginalis sac be opened or closed in pediatric herniotomy? A two-center cohort study
Michler V, Elrod J, Wingtes K, Trah J, Reinshagen K, Boettcher M
PEDIATR SURG INT. 2022;38(8):1165-1169.

High prevalence of multidrug-resistant Gram-negative bacteria carriage in children screened prospectively for multidrug resistant organisms at admission to a paediatric hospital, Hamburg, Germany, September 2018 to May 2019
Najem S, Eick D, Boettcher J, Aigner A, Aboutara M, Fenner I, Reinshagen K, Koenigs I
EUROSURVEILLANCE. 2022;27(15):.

In Reply
Reinshagen K
DTSCH ARZTEBL INT. 2022;119(12):218.

Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis
Reinshagen K, Burmester G, Hagens J, Krebs T, Tomuschat C
CHILDREN-BASEL. 2022;9(1):.

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
Schmidt H, Hagens J, Schuppert P, Philippi C, Reinshagen K, Tomuschat C
JOVE-J VIS EXP. 2022;186:.

Limits in Laparoscopic Partial Splenectomy in Children
Tomuschat C, Aftzoglou M, Hagens J, Boettcher M, Reinshagen K
CHILDREN-BASEL. 2022;9(5):.

The Length of the Transition Zone in Patients with Rectosigmoid Hirschsprung Disease
Tomuschat C, Mietzsch S, Dwertmann-Rico S, Clauditz T, Schaefer H, Reinshagen K
CHILDREN-BASEL. 2022;9(2):.

Aplasia Cutis Congenita mit Fetus Papyraceus (ACC Typ 5) – eine Blickdiagnose
Aboutara M, von der Wense A, Fattouh M, Reinshagen K, Koenigs I
KLIN PADIATR. 2021;233(2):69-71.

Fatal COVID-19 in a Child with Persistence of SARS-CoV-2 Despite Extensive Multidisciplinary Treatment: A Case Report
Apostolidou S, Harbauer T, Lasch P, Biermann D, Hempel M, Lütgehetmann M, Pfefferle S, Herrmann J, Rüffer A, Reinshagen K, Kozlik-Feldmann R, Gieras A, Kniep I, Oh J, Singer D, Ebenebe C, Kobbe R
CHILDREN-BASEL. 2021;8(7):.

Stereological Lung Parameters After Fetoscopic Abdominal Decompression of Congenital Diaphragmatic Hernia in an Ovine Model: A Pilot Study
Bergholz R, Fromm F, Meinzer A, Muehlfeld C, Boettcher M, Wenke K, Tiemann B, Reinshagen K, Krebs T
J LAPAROENDOSC ADV S. 2021;31(6):712-718.

Fetoscopic techniques for prenatal covering of gastroschisis in an ovine model are technically demanding and do not lead to permanent anchoring on the fetus until the end of gestation
Bergholz R, Krebs T, Cremieux B, Georgi C, Fromm F, Boettcher M, Andreas T, Tiemann B, Wenke K, Reinshagen K, Hecher K
SURG ENDOSC. 2021;35(2):745-753.

Perceived mental health in parents of children with rare congenital surgical diseases: a double ABCX model considering gender
Boettcher J, Zapf H, Fuerboeter M, Nazarian R, Reinshagen K, Wiegand-Grefe S, Boettcher M
ORPHANET J RARE DIS. 2021;16(1):384.

Combination of Side-Swing Flap With Negative-Pressure Wound Therapy Is Superior to Open Excision or Flap Alone in Children With Pilonidal Sinus-But at What Cost?
Dorth D, Königs I, Elrod J, Ghadban T, Reinshagen K, Boettcher M
FRONT PEDIATR. 2021;9:595684.

Analyse der Versorgungsstruktur angeborener Fehlbildungen in Deutschland
Elrod J, Boettcher M, Mohr C, Reinshagen K
DTSCH ARZTEBL INT. 2021;2021(35-36):601-602.

Portal venous gas in a girl with chronic intestinal pseudoobstruction
Elrod J, Reinshagen K, Boettcher M
SURGERY. 2021;170(4):e17-e19.

Quality of life and mental health of children with rare congenital surgical diseases and their parents during the COVID-19 pandemic
Fuerboeter M, Boettcher J, Barkmann C, Zapf H, Nazarian R, Wiegand-Grefe S, Reinshagen K, Boettcher M
ORPHANET J RARE DIS. 2021;16(1):498.

Effects of Educational Video on Pre-operative Anxiety in Children - A Randomized Controlled Trial
Härter V, Barkmann C, Wiessner C, Rupprecht M, Reinshagen K, Trah J
FRONT PEDIATR. 2021;9:640236.

Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice
Heuer A, Stiel C, Elrod J, Königs I, Vincent D, Schlegel P, Trochimiuk M, Appl B, Reinshagen K, Raluy L, Boettcher M
FRONT IMMUNOL. 2021;12:.

Erworbener Chylothorax im Säuglingsalter
Hickmann D, Maiberger T, von der Wense A, Reinshagen K
MONATSSCHR KINDERH. 2021.

KIR3DS1 directs NK cell-mediated protection against human adenovirus infections
Jung J, Ching W, Baumdick M, Hofmann-Sieber H, Bosse J, Koyro T, Möller K, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen S, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans C, Altfeld M, Belderbos M, Dobner T, Bunders M
SCI IMMUNOL. 2021;6(63):.

Cardiac and Inflammatory Necrotizing Enterocolitis in Newborns Are Not the Same Entity
Klinke M, Wiskemann H, Bay B, Schäfer H, Pagerols Raluy L, Reinshagen K, Vincent D, Boettcher M
FRONT PEDIATR. 2021;8:.

Traumatic Gallbladder Perforation in Children - Case Report and Review
Le M, Herrmann J, Groth M, Reinshagen K, Boettcher M
ROFO-FORTSCHR RONTG. 2021;193(8):889-897.

Case Report: True Thymic Hyperplasia in a 30-Day-Old Boy
Mokhaberi N, Woessmann W, Schäfer H, Blohm M, Groth M, Reinshagen K
KLIN PADIATR. 2021;233(6):299-302.

Intestinal CD8+ T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities
Schreurs R, Sagebiel A, Steinert F, Highton A, Klarenbeek P, Drewniak A, Bakx R, The S, Ribeiro C, Perez D, Reinshagen K, Geijtenbeek T, van Goudoever J, Bunders M
MUCOSAL IMMUNOL. 2021;14(3):605-614.

Time- and dose-dependent inhibition of neutrophil extracellular trap formation by blocking of the interleukin-1 receptor
Wadehn H, Pagerols Raluy L, Kolman J, Dücker C, Trochimiuk M, Appl B, Boettcher M, Reinshagen K, Trah J
CENT EUR J IMMUNOL. 2021;46(4):419-426.

Hirschsprung Disease - Clinical Relevance of RET Mutations
Wenskus J, Vincent D, Hempel M, Reinshagen K
Z GEBURTSH NEONATOL. 2021;225(1):80-82.

The ABSI is dead, long live the ABSI - reliable prediction of survival in burns with a modified Abbreviated Burn Severity Index
Bartels P, Thamm O, Elrod J, Fuchs P, Reinshagen K, German Burn Registry , Koenigs I
BURNS. 2020;46(6):1272-1279.

Evaluation of a new robotic-assisted laparoscopic surgical system for procedures in small cavities
Bergholz R, Botden S, Verweij J, Tytgat S, Van Gemert W, Boettcher M, Ehlert H, Reinshagen K, Gidaro S
J ROBOT SURG. 2020;14(1):191-197.

Spaced Education Improves the Retention of Laparoscopic Suturing Skills: A Randomized Controlled Study
Boettcher J, Klippgen L, Mietzsch S, Grube F, Krebs T, Bergholz R, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2020;30(2):193-200.

The Spaced Learning Concept Significantly Improves Acquisition of Laparoscopic Suturing Skills in Students and Residents: A Randomized Control Trial
Boettcher J, Mietzsch S, Wenkus J, Mokhaberi N, Klinke M, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2020;2020(30):541-547.

Markers of neutrophil activation and extracellular traps formation are predictive of appendicitis in mice and humans: a pilot study
Boettcher M, Esser M, Trah J, Klohs S, Mokhaberi N, Wenskus J, Trochimiuk M, Appl B, Reinshagen K, Raluy L, Klinke M
SCI REP-UK. 2020;10(1):18240.

Digestive enzyme expression in the large intestine of children with short bowel syndrome in a late stage of adaptation
de Laffolie J, Sheridan D, Reinshagen K, Wessel L, Zimmermann C, Stricker S, Lerch M, Weigel M, Hain T, Domann E, Rudloff S, Nichols B, Naim H, Zimmer K
FASEB J. 2020;34(3):3983-3995.

Low gestational age is associated with less anastomotic complications after open primary repair of esophageal atresia with tracheoesophageal fistula
Dingemann C, Brendel J, Wenskus J, Pirr S, Schukfeh N, Ure B, Reinshagen K
BMC PEDIATR. 2020;20(1):267.

Using Artificial Intelligence to Obtain More Evidence? Prediction of Length of Hospitalization in Pediatric Burn Patients
Elrod J, Mohr C, Wolff R, Boettcher M, Reinshagen K, Bartels P, Koenigs I
FRONT PEDIATR. 2020;8:613736.

Infantile Hepatic Hemangioma: Avoiding Unnecessary Invasive Procedures
Ernst L, Grabhorn E, Brinkert F, Reinshagen K, Königs I, Trah J
PEDIATR GASTROENTERO. 2020;23(1):72-78.

Ultrasound-guided ilioinguinal-iliohypogastric block (ILIHB) or perifocal wound infiltration (PWI) in children: a prospective randomized comparison of analgesia quality, a pilot study
Grosse B, Eberbach S, Pinnschmidt H, Vincent D, Schmidt-Niemann M, Reinshagen K
BMC ANESTHESIOL. 2020;20(1):256.

Life-Threatening Mediastinal Shift due to a Giant Bronchogenic Cyst
Hüners I, Boettcher M, Holst T, Groth M, Stark V, Köhne M, Lennartz M, Sachweh J, Reinshagen K, Biermann D
KLIN PADIATR. 2020;232(5):269-271.

The BAL-Score Almost Perfectly Predicts Testicular Torsion in Children: A Two-Center Cohort Study
Klinke M, Elrod J, Stiel C, Ghadban T, Wenskus J, Herrmann J, Junge C, Reinshagen K, Boettcher M
FRONT PEDIATR. 2020;8:601892.

Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis
Klinke M, Vincent D, Trochimiuk M, Appl B, Tiemann B, Reinshagen K, Raluy L, Boettcher M
SCI REP-UK. 2020;10(1):8049.

Lidocaine-Epinephrine-Tetracaine Gel Is More Efficient than Eutectic Mixture of Local Anesthetics and Mepivacaine Injection for Pain Control during Skin Repair in Children: A Prospective, Propensity Score Matched Two-Center Study
Königs I, Wenskus J, Boettcher J, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2020;30(6):512-516.

Classical but Not Rap Music Significantly Improves Transferability and Long-Term Acquisition of Laparoscopic Suturing Skills: A Randomized Controlled Trial
Mietzsch S, Bergholz R, Boettcher J, Klippgen L, Wenskus J, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2020;30(6):541-547.

Kindeswohlgefährdung – Ausweitung des Hellfeldes durch Neukonzeption der klinischen Kinderschutzarbeit
Schmidt C, Klein S, Stock P, Reinshagen K, Königs I
BUNDESGESUNDHEITSBLA. 2020;63(10):1241-1249.

The Inhibitory Effect of Curosurf® and Alveofact® on the Formation of Neutrophil Extracellular Traps
Schulz A, Pagerols Raluy L, Kolman J, Königs I, Trochimiuk M, Appl B, Reinshagen K, Boettcher M, Trah J
FRONT IMMUNOL. 2020;11:582895.

Markers of NETosis Do Not Predict Neonatal Early Onset Sepsis: A Pilot Study
Stiel C, Ebenebe C, Trochimiuk M, Pagarols Raluy L, Vincent D, Singer D, Reinshagen K, Boettcher M
FRONT PEDIATR. 2020;7:.

The Modified Heidelberg and the AI Appendicitis Score Are Superior to Current Scores in Predicting Appendicitis in Children: A Two-Center Cohort Study
Stiel C, Elrod J, Klinke M, Herrmann J, Junge C, Ghadban T, Reinshagen K, Boettcher M
FRONT PEDIATR. 2020;8:592892.

Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option
Trah J, Arand J, Oh J, Pagerols-Raluy L, Trochimiuk M, Appl B, Heidelbach H, Vincent D, Saleem M, Reinshagen K, Mühlig A, Boettcher M
SCI REP-UK. 2020;10(1):20349.

The Impact of Oral Sodium Chloride Supplementation on Thrive and the Intestinal Microbiome in Neonates With Small Bowel Ostomies: A Prospective Cohort Study
Trautmann T, Bang C, Franke A, Vincent D, Reinshagen K, Boettcher M
FRONT IMMUNOL. 2020;11:1421.

Ileumpouch bei Patienten mit Zuelzer-Wilson-Syndrom – Bedeutung für die Patienten?
Wenskus J, Burmester G, Staude C, Krebs T, Reinshagen K
MONATSSCHR KINDERH. 2020;168(11):1032-1039.

Degradation of Extracellular DNA Significantly Ameliorates Necrotizing Enterocolitis Severity in Mice
Klinke M, Vincent D, Trochimiuk M, Appl B, Tiemann B, Bergholz R, Reinshagen K, Boettcher M
J SURG RES. 2019;235:513-520.

Rescue Nuss procedure for inferior vena cava compression syndrome following posterior scoliosis surgery in Marfan syndrome
Löhnhardt M, Hättich A, Andresen A, Stangenberg M, Mir T, Reinshagen K, Dreimann M
EUR SPINE J. 2019;28(Suppl 2):31-36.

angeborene Zwerchfellhernie
Reinshagen K, Lüers S
2019. OP Handbuch. Liehn M, Lengersdorf B, Steinmüller L, Döhler R (Hrsg.). 7. Aufl. Berlin: Springer, 616-619.

Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
Sagebiel A, Steinert F, Lunemann S, Körner C, Schreurs R, Altfeld M, Perez D, Reinshagen K, Bunders M
NAT COMMUN. 2019;10(1):975.

Human Fetal TNF-α-Cytokine-Producing CD4 Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life
Schreurs R, Baumdick M, Sagebiel A, Kaufmann M, Mokry M, Klarenbeek P, Schaltenberg N, Steinert F, van Rijn J, Drewniak A, The S, Bakx R, Derikx J, de Vries N, Corpeleijn W, Pals S, Gagliani N, Friese M, Middendorp S, Nieuwenhuis E, Reinshagen K, Geijtenbeek T, van Goudoever J, Bunders M
IMMUNITY. 2019;50(2):462-476.e8.

The spaced learning concept significantly improves training for laparoscopic suturing: a pilot randomized controlled study
Boettcher M, Boettcher J, Mietzsch S, Krebs T, Bergholz R, Reinshagen K
SURG ENDOSC. 2018;32(1):154-159.

Haarabschnürung im Bereich des weiblichen Genitale bei Kindern
Dorth D, Reinshagen K, Königs I
KLIN PADIATR. 2018;230(6):328-329.

Vincristine resistance in relapsed neuroblastoma can be efficiently overcome by Smac mimetic LCL161 treatment
Frommann K, Appl B, Hundsdoerfer P, Reinshagen K, Eschenburg G
J PEDIATR SURG. 2018;53(10):2059-2064.

Dunkelziffer nicht-akzidenteller thermischer Verletzungen im Kindesalter – Kinderschutzstrategien zur Reduktion
Klinke M, Schmidt C, Tegtmeyer L, Reinshagen K, Boettcher M, Koenigs I
KLIN PADIATR. 2018;230(2):61-67.

Retrospective analysis on thermal injuries in children-Demographic, etiological and clinical data of German and Austrian pediatric hospitals 2006-2015-Approaching the new German burn registry
Tegtmeyer L, Herrnstadt G, Maier S, Thamm O, Klinke M, Reinshagen K, Koenigs I
BURNS. 2018;44(1):150-157.

Integra®-Dermal Regeneration Template and Split-Thickness Skin Grafting: A Therapy Approach to Correct Aplasia Cutis Congenita and Epidermolysis Bullosa in Carmi Syndrome
Trah J, Has C, Hausser I, Kutzner H, Reinshagen K, Königs I
DERMATOLOGY THER. 2018;8(2):313-321.

NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans
Vincent D, Klinke M, Eschenburg G, Trochimiuk M, Appl B, Tiemann B, Bergholz R, Reinshagen K, Boettcher M
SCI REP-UK. 2018;8(1):12612.

Ätiologie der Gastroschisis und Ansätze für eine pränatale Chirurgie
Bergholz R, Reinshagen K
Gynäkologische Praxis. 2017;42(2):289-298.

Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats
Boettcher M, Eschenburg G, Mietzsch S, Jiménez-Alcázar M, Klinke M, Vincent D, Tiemann B, Bergholz R, Reinshagen K, Fuchs T
SCI REP-UK. 2017;7(1):15377.

Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage after Testicular Torsion in Rats
Boettcher M, Meier D, Jiménez-Alcázar M, Eschenburg G, Mietzsch S, Vincent D, Klinke M, Trochimiuk M, Appl B, Tiemann B, Bergholz R, Reinshagen K, Fuchs T
UROLOGY. 2017;109:223.e1-223.e7.

Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α
Langemann D, Trochimiuk M, Appl B, Hundsdoerfer P, Reinshagen K, Eschenburg G
ONCOTARGET. 2017;8(50):87763-87772.

Kinder und Jugendliche
Reinshagen K
2017. Perioperative Medizin. Schwenk W, Freys S, Kalff J (Hrsg.). 1. Aufl. Stuttgart: Georg Thieme Verlag KG, 448-453.

Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a Triterpene Extract
Ueck C, Volksdorf T, Houdek P, Vidal-Y-Sy S, Sehner S, Ellinger B, Lobmann R, Larena-Avellaneda A, Reinshagen K, Ridderbusch I, Kohrmeyer K, Moll I, Daniels R, Werner P, Merfort I, Brandner J
PLOS ONE. 2017;12(1):e0169028.

Urinöser Aszites bei Sinus-urogenitalis-Fehlbildung.
Wolf M, Bergholz R, Diehl T, Thayssen M, Diemert A, Reinshagen K, Singer D
Z GEBURTSH NEONATOL. 2017;221(04):198-200.

Epidemiologic analysis of families with isolated anorectal malformations suggests high prevalence of autosomal dominant inheritance
Zwink N, Dworschak G, Schmiedeke E, Mortazawi K, Märzheuser S, Reinshagen K, Leonhardt J, Gómez B, Volk P, Rißmann A, Jenetzky E, Reutter H
ORPHANET J RARE DIS. 2017;12(1):180.

Carbonic anhydrase IX correlates with survival and is a potential therapeutic target for neuroblastoma
Ameis H, Drenckhan A, Freytag M, Izbicki J, Supuran C, Reinshagen K, Holland-Cunz S, Gros S
J ENZYM INHIB MED CH. 2016;31(3):404-9.

Influence of hypoxia-dependent factors on the progression of neuroblastoma
Ameis H, Drenckhan A, Freytag M, Izbicki J, Supuran C, Reinshagen K, Holland-Cunz S, Gros S
PEDIATR SURG INT. 2016;32(2):187-92.

Modulation of Thrombosis Significantly Reduces Testicular Damage after Testicular Torsion in Rats: Anti-Thrombotic Treatment and Testicular Torsion
Boettcher M, Fuchs T, Schäfer H, Appl B, Trochimiuk M, Jiménez-Alcázar M, Tiemann B, Jung R, Bergholz R, Reinshagen K, Eschenburg G
UROLOGY. 2016;88(227):e1-7.

Sternumaplasie (Sternal Cleft).
Gerling J, Boettcher M, Mietzsch S, Pawlik M, Klaassen I, Hempel M, Reinshagen K, Singer D
Z GEBURTSH NEONATOL. 2016;220:269-270.

Training Significantly Improves Fetoscopy Performance: A Pilot Randomized Controlled Trial
Mietzsch S, Boettcher J, Yang S, Chantereau P, Romero P, Bergholz R, Reinshagen K, Boettcher M
EUR J PEDIATR SURG. 2016;26(5):436-442.

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L
Najem S, Langemann D, Appl B, Trochimiuk M, Hundsdoerfer P, Reinshagen K, Eschenburg G
ONCOTARGET. 2016;7(45):72634-72653.

Major cell biological parameters of keratinocytes are predetermined by culture medium and donor source
Zorn-Kruppa M, Volksdorf T, Ueck C, Zöller E, Reinshagen K, Ridderbusch I, Bruning G, Houdek P, Moll I, Brandner J
EXP DERMATOL. 2016;25(3):242-4.

Midterm Outcome of Transumbilically Laparoscopic-Assisted Versus Laparoscopic and Open Appendectomy in Children-A Matched Prospective Study
Bergholz R, Klein I, Wenke K, Boettcher M, Reinshagen K, Krebs T
EUR J PEDIATR SURG. 2015;25(2):216-219.

Spezifische Symptomkombination der chronischen Quecksilberintoxikation: Arterielle Hypertension, Entwicklungsregression und Automutilation
Hermann K, Varwig-Janßen D, Budnik L, Nordholt G, Reinshagen K, Oh J, Santer R, Mühlhausen C
MONATSSCHR KINDERH. 2015;163(6):570-574.

A Chicken Embryo Model for the Study of Umbilical and Supraumbilical Body Wall Malformations
Ridderbusch I, Bergholz R, Fattouh M, Eschenburg G, Roth B, Appl B, Maenner J, Reinshagen K, Kluth D
EUR J PEDIATR SURG. 2015;25(3):257-261.

Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis
Bergholz R, Boettcher M, Reinshagen K, Wenke K
J PEDIATR SURG. 2014;49(10):1527-32.

Transumbilical Laparoscopic-assisted Versus 3-Port Laparoscopic and Open Appendectomy: A Case-Control Study in Children
Bergholz R, Krebs T, Klein I, Wenke K, Reinshagen K
SURG LAPARO ENDO PER. 2014;24(3):244-7.

Prenatal latex sensitization in patients with spina bifida: a pilot study
Boettcher M, Göttler S, Eschenburg G, Kracht T, Kunkel P, Von der Wense A, Reinshagen K
J NEUROSURG-PEDIATR. 2014;13(3):291-4.

Akutes Skrotum bei Kindern
Boettcher M, Reinshagen K
Päd Praxis. 2014;85(2):100-107.

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells
Eschenburg G, Luckert C, Reinshagen K, Bergholz R
Genes Cancer. 2014;5(11-12):460-9.

Gut inflammation and expression of ICC in a fetal lamb model of fetoscopic intervention for gastroschisis
Krebs T, Boettcher M, Schäfer H, Eschenburg G, Wenke K, Appl B, Roth B, Andreas T, Schmitz C, Fahje R, Jacobsen B, Tiemann B, Reinshagen K, Hecher K, Bergholz R
SURG ENDOSC. 2014;28(8):2437-2442.

Taurolidine specifically inhibits growth of neuroblastoma cell lines in vitro
Luckert C, Eschenburg G, Roth B, Appl B, Reinshagen K, Bergholz R
J PEDIAT HEMATOL ONC. 2014;36(4):e219-23.

Therapie traumatischer Pankreasverletzungen im Kindesalter
Maier S, Reinshagen K, Kähler G, Wessel L
ZBL CHIR. 2014;139(3):266-70.

Sensitivierung für Zytostatika-vermittelte Apoptose-Induktion durch Smac mimetic LCL161 beim Neuroblastom
Najem S, Hundsdoerfer P, Reinshagen K, Eschenburg G
2014. 109. Jahrestagung der Deutschen Gesellschaft für Kinder- und Jugendmedizin e.V. (DGKJ); . .

Anastomosis instead of resection: An unusual approach for the treatment of a cervical esophagela duplication cyst
Reinshagen K, Wenke K
J PEDIAT SURG CASE R. 2014;2(3):93-96.

Neonatale Erstversorgung - "Atypische Intubation" bei Trachealagenesie
Wolf M, Klaassen I, Reinshagen K, Herrmann J, Singer D
Z GEBURTSH NEONATOL. 2014;218(2):87-8.

PGK1 as predictor of CXCR4 expression, bone marrow metastases and survival in neuroblastoma
Ameis H, Drenckhan A, Loga K, Escherich G, Wenke K, Izbicki J, Reinshagen K, Gros S
PLOS ONE. 2013;8(12):e83701.

Abdominal wall incision with or without exteriorization of bowel: results from a fetal lamb model for the embryogenesis of gastroschisis
Bergholz R, Krebs T, Wenke K, Boettcher M, Andreas T, Tiemann B, Jacobsen B, Fahje R, Schmitz C, Roth B, Appl B, Reinshagen K, Hecher K
FETAL DIAGN THER. 2013;33(1):55-60.

Mucosal loss with increased expression of IL-6, IL-8, and COX-2 in a formula-feeding only neonatal rat model of necrotizing enterocolitis
Bergholz R, Zschiegner M, Eschenburg G, Wenke K, Tiemann B, Roth B, Appl B, Reinshagen K, Sommerfeldt D, Ridderbusch I
J PEDIATR SURG. 2013;48(11):2301-7.

Differentiation of epididymitis and appendix testis torsion by clinical and ultrasound signs in children
Boettcher M, Bergholz R, Krebs T, Wenke K, Treszl A, Aronson D, Reinshagen K
UROLOGY. 2013;82(4):899-904.

Concomitant bilateral adnexal entanglement in a 7-year-old girl with precocious puberty
Boettcher M, Kanellos-Becker I, Akkurt I, Reinshagen K
INT J GYNECOL OBSTET. 2013;123(3):248-9.

Clinical and sonographic features predict testicular torsion in children: a prospective study
Boettcher M, Krebs T, Bergholz R, Wenke K, Aronson D, Reinshagen K
J UROLOGY. 2013;112(8):1201-6.

[Therapy of Paediatric Pancreatic Trauma.]
Maier S, Reinshagen K, Kähler G, Wessel L
ZBL CHIR. 2013.

Ultra late onset group B streptococcal sepsis with acute renal failure in a child with urethral obstruction: a case report.
Freudenstein D, Reinshagen K, Petzold A, Debus A, Schroten H, Tenenbaum T
J MED CASE REP. 2012;6:68.

Right- versus left-sided congenital diaphragmatic hernia: postnatal outcome at a specialized tertiary care center.
Schaible T, Kohl T, Reinshagen K, Brade J, Neff K, Stressig R, Büsing K
PEDIATR CRIT CARE ME. 2012;13(1):66-71.

Candidiasis caused by Candida kefyr in a neonate: case report.
Weichert S, Reinshagen K, Zahn K, Geginat G, Dietz A, Kilian A, Schroten H, Tenenbaum T
BMC INFECT DIS. 2012;12:61.

Preventive antireflux surgery in neonates with congenital diaphragmatic hernia: a single-blinded prospective study.
Maier S, Zahn K, Wessel L, Schaible T, Brade J, Reinshagen K
J PEDIATR SURG. 2011;46(8):1510-1515.

A 20-year experience on neonatal extracorporeal membrane oxygenation in a referral center
Schaible T, Hermle D, Loersch F, Demirakca S, Reinshagen K, Varnholt V
INTENS CARE MED. 2010;36(7):1229-34.

Transanal pull-through procedure for Hirschsprung's disease: a 5-year experience
Jester I, Holland-Cunz S, Loff S, Hosie S, Reinshagen K, Wirth H, Ali M, Waag K
EUR J PEDIATR SURG. 2009;19(2):68-71.

The chronic liver disease in patients with short bowel syndrome: etiology and treatment
Reinshagen K, Adams R, Trunk M, Wessel L
MINERVA PEDIATR. 2009;61(3):273-81.

Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring
Reinshagen K, Kabs C, Wirth H, Hable N, Brade J, Zahn K, Hagl C, Jester I, Waag K
J PEDIATR GASTR NUTR. 2008;47(5):573-8.

Evaluation von Stents zur Behandlung der benignen Osophagusstenose im Kindesalter
Reinshagen K, Kähler G, Manegold B, Waag K
KLIN PADIATR. 2008;221(1):25-30.

Mosaic pattern of sucrase isomaltase deficiency in two brothers
Reinshagen K, Keller K, Haase B, Leeb T, Naim H, Zimmer K
PEDIATR RES. 2008;63(1):79-83.

The impact of longitudinal intestinal lengthening and tailoring on liver function in short bowel syndrome
Reinshagen K, Zahn K, Buch C, Zoeller M, Hagl C, Ali M, Waag K
EUR J PEDIATR SURG. 2008;18(4):249-53.

Behandlung von Lymphangiomen mit Picibanil im ersten Lebensjahr
Subotic U, Hosie S, Waag K, Reinshagen K
KLIN PADIATR. 2008;220(4):248-52.

Efficacy of ERCP in infancy and childhood
Reinshagen K, Müldner A, Manegold B, Kähler G
KLIN PADIATR. 2007;219(5):271-6.

Gastrobronchial fistula after toothbrush ingestion
Karcher J, von Buch C, Waag K, Reinshagen K
J PEDIATR SURG. 2006;41(10):1768-70.

Pathophysiology in Microvillus inclusion disease
Reinshagen K, Naim H, Heusipp G, Zimmer K
Z GASTROENTEROL. 2006;44(8):667-71.

Modified self-expanding plastic stent for the treatment of refractory benign esophageal strictures
Müldner A, Reinshagen K, Wüstner M, Kähler G
ENDOSCOPY. 2005;37(9):925.

Endoscopically controlled strictureplasty for stenotic colorectal anastomosis
Reinshagen K, Müldner A, Reinshagen S, Kähler G
ENDOSCOPY. 2005;37(9):873-5.

A case of severe Pierre Robin sequence with failure to thrive and tachycardia resolved after redo-fundoplication and hiatoplasty
Reinshagen K, Schellscheidt J, Zimmer K
EUR J PEDIATR. 2005;164(9):573-6.

Autophagocytosis of the apical membrane in microvillus inclusion disease
Reinshagen K, Naim H, Zimmer K
GUT. 2002;51(4):514-21.

Congenital epulis: a rare diagnosis in paediatric surgery
Reinshagen K, Wessel L, Roth H, Waag K
EUR J PEDIATR SURG. 2002;12(2):124-6.

Ein einfaches Hilfsmittel der Gastroenterologie. Auch die Magensonde hat ihre Risiken
Reinshagen K, Imdahl A
MMW Fortschr Med. 2000;142(14):35-6.

Letzte Aktualisierung aus dem FIS: 20.12.2024 - 23:36 Uhr