A comprehensive comparison of deep learning-based compound-target interaction prediction models to unveil guiding design principles
Abdollahi S, Schaub D, Barroso M, Laubach N, Hutwelker W, Panzer U, Gersting S, Bonn S
J CHEMINFORMATICS. 2024;16(1):118.

Miniproteins may have a big impact: new therapeutics for autoimmune diseases and beyond
Asada N, Krebs C, Panzer U
SIGNAL TRANSDUCT TAR. 2024;9(1):298.

C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner
Dey I, Li Y, Taylor T, Peroumal D, Asada N, Panzer U, Biswas P, Sterneck E, Gaffen S
J IMMUNOL. 2024;213(6):767-778.

Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis
Engesser J, Khatri R, Schaub D, Zhao Y, Paust H, Sultana Z, Asada N, Riedel J, Sivayoganathan V, Peters A, Kaffke A, Jauch-Speer S, Goldbeck-Strieder T, Puelles V, Wenzel U, Steinmetz O, Hoxha E, Turner J, Mittrücker H, Wiech T, Huber T, Bonn S, Krebs C, Panzer U
NAT COMMUN. 2024;15(1):8220.

Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
Enk L, Hellmig M, Riecken K, Kilian C, Datlinger P, Jauch-Speer S, Neben T, Sultana Z, Sivayoganathan V, Borchers A, Paust H, Zhao Y, Asada N, Liu S, Agalioti T, Pelczar P, Wiech T, Bock C, Huber T, Huber S, Bonn S, Gagliani N, Fehse B, Panzer U, Krebs C
SCI IMMUNOL. 2024;9(96):eadd6774.

The RNA binding protein Arid5a drives IL-17-dependent autoantibody-induced glomerulonephritis
Li Y, Vyas S, Mehta I, Asada N, Dey I, Taylor T, Bechara R, Amatya N, Aggor F, Coleman B, Li D, Yamamoto K, Ezenwa O, Sun Y, Sterneck E, McManus C, Panzer U, Biswas P, Savan R, Das J, Gaffen S
J EXP MED. 2024;221(9):.

Targeting monocyte derived CCL17 attenuates murine crescentic glomerulonephritis by affecting renal CCR4+ regulatory T cell recruitment
Song N, Paust H, Asada N, Peters A, Kaffke A, Krebs C, Panzer U, Riedel J
AM J NEPHROL. 2024;55(2):214-224.

γδ T cells in immune-mediated kidney disease
Waterhölter A, Krebs C, Panzer U
EUR J IMMUNOL. 2024;54(12):e2451069.

Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory N, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt M, Bono M, Gagliani N, Sandrock I, Panzer U, Krebs C, Meyer-Schwesinger C, Prinz I, Mittrücker H
P NATL ACAD SCI USA. 2023;120(1):e2210490120.

Tissue-resident memory T cells in renal autoimmune diseases
Ginsberg P, Panzer U, Asada N
FRONT IMMUNOL. 2023;14:1111521.

Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease
Gnirck A, Philipp M, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, Tomczyk P, Al-Bahra M, Menche D, Walkenhorst M, Lantz O, Willing A, Friese M, Huber T, Krebs C, Panzer U, Kurts C, Turner J
NAT COMMUN. 2023;14(1):.

The CCR6/CCL20 Axis Expands RORγt+ Tregs to Protect from Glomerulonephritis
Herrnstadt G, Niehus C, Ramcke T, Hagenstein J, Ehnold L, Nosko A, Warkotsch M, Feindt F, Melderis S, Paust H, Sivayoganathan V, Jauch-Speer S, Wong M, Indenbirken D, Krebs C, Huber T, Panzer U, Puelles V, Kluger M, Steinmetz O
KIDNEY INT. 2023;104(1):74-89.

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy
Kiryluk K, Sanchez-Rodriguez E, Zhou X, Zanoni F, Liu L, Mladkova N, Khan A, Marasa M, Zhang J, Balderes O, Sanna-Cherchi S, Bomback A, Canetta P, Appel G, Radhakrishnan J, Trimarchi H, Sprangers B, Cattran D, Reich H, Pei Y, Ravani P, Galesic K, Maixnerova D, Tesar V, Stengel B, Metzger M, Canaud G, Maillard N, Berthoux F, Berthelot L, Pillebout E, Monteiro R, Nelson R, Wyatt R, Smoyer W, Mahan J, Samhar A, Hidalgo G, Quiroga A, Weng P, Sreedharan R, Selewski D, Davis K, Kallash M, Vasylyeva T, Rheault M, Chishti A, Ranch D, Wenderfer S, Samsonov D, Claes D, Akchurin O, Goumenos D, Stangou M, Nagy J, Kovacs T, Fiaccadori E, Amoroso A, Barlassina C, Cusi D, Del Vecchio L, Battaglia G, Bodria M, Boer E, Bono L, Boscutti G, Caridi G, Lugani F, Ghiggeri G, Coppo R, Peruzzi L, Esposito V, Esposito C, Feriozzi S, Polci R, Frasca G, Galliani M, Garozzo M, Mitrotti A, Gesualdo L, Granata S, Zaza G, Londrino F, Magistroni R, Pisani I, Magnano A, Marcantoni C, Messa P, Mignani R, Pani A, Ponticelli C, Roccatello D, Salvadori M, Salvi E, Santoro D, Gembillo G, Savoldi S, Spotti D, Zamboli P, Izzi C, Alberici F, Delbarba E, Florczak M, Krata N, Mucha K, Pączek L, Niemczyk S, Moszczuk B, Pańczyk-Tomaszewska M, Mizerska-Wasiak M, Perkowska-Ptasińska A, Bączkowska T, Durlik M, Pawlaczyk K, Sikora P, Zaniew M, Kaminska D, Krajewska M, Kuzmiuk-Glembin I, Heleniak Z, Bullo-Piontecka B, Liberek T, Dębska-Slizien A, Hryszko T, Materna-Kiryluk A, Miklaszewska M, Szczepańska M, Dyga K, Machura E, Siniewicz-Luzeńczyk K, Pawlak-Bratkowska M, Tkaczyk M, Runowski D, Kwella N, Drożdż D, Habura I, Kronenberg F, Prikhodina L, van Heel D, Fontaine B, Cotsapas C, Wijmenga C, Franke A, Annese V, Gregersen P, Parameswaran S, Weirauch M, Kottyan L, Harley J, Suzuki H, Narita I, Goto S, Lee H, Kim D, Kim Y, Park J, Cho B, Choi M, Van Wijk A, Huerta A, Ars E, Ballarin J, Lundberg S, Vogt B, Mani L, Caliskan Y, Barratt J, Abeygunaratne T, Kalra P, Gale D, Panzer U, Rauen T, Floege J, Schlosser P, Ekici A, Eckardt K, Chen N, Xie J, Lifton R, Loos R, Kenny E, Ionita-Laza I, Köttgen A, Julian B, Novak J, Scolari F, Zhang H, Gharavi A
NAT GENET. 2023;55(7):1091-1105.

Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller A, Zhao Y, Cicek H, Paust H, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber T, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs C, Neumann K
J AM SOC NEPHROL. 2023;34(6):1003-1018.

CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12
Paust H, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel J, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel U, Steinmetz O, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer M, Hoxha E, Stahl R, Huber T, Bonn S, Meyer-Schwesinger C, Wiech T, Turner J, Becher B, Krebs C, Panzer U
SCI TRANSL MED. 2023;15(687):.

Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury
Riedel J, Robben L, Paust H, Zhao Y, Asada N, Song N, Peters A, Kaffke A, Borchers A, Tiegs G, Seifert L, Tomas N, Hoxha E, Wenzel U, Huber T, Wiech T, Turner J, Krebs C, Panzer U
JCI INSIGHT. 2023;8(1):.

The classical pathway triggers pathogenic complement activation in membranous nephropathy
Seifert L, Zahner G, Meyer-Schwesinger C, Hickstein N, Dehde S, Wulf S, Köllner S, Lucas R, Kylies D, Froembling S, Zielinski S, Kretz O, Borodovsky A, Biniaminov S, Wang Y, Cheng H, Koch-Nolte F, Zipfel P, Hopfer H, Puelles V, Panzer U, Huber T, Wiech T, Tomas N
NAT COMMUN. 2023;14(1):473.

Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites
Shaikh N, Waterhölter A, Gnirck A, Becker M, Adamiak V, Henneken L, Wunderlich M, Hartmann W, Linnemann L, Huber T, Krebs C, Panzer U, Locksley R, Wilhelm C, Breloer M, Turner J
J EXP MED. 2023;220(12):.

IKK1 aggravates ischemia-reperfusion kidney injury by promoting the differentiation of effector T cells
Song N, Xu Y, Paust H, Panzer U, Noriega M, Guo L, Renne T, Huang J, Meng X, Zhao M, Thaiss F
CELL MOL LIFE SCI. 2023;80(5):125.

Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis
Soukou-Wargalla S, Kilian C, Velasquez L, Machicote A, Letz P, Tran H, Domanig S, Bertram F, Stumme F, Bedke T, Giannou A, Kempski J, Sabihi M, Song N, Paust H, Borchers A, Garcia Perez L, Pelczar P, Liu B, Ergen C, Steglich B, Muscate F, Huber T, Panzer U, Gagliani N, Krebs C, Huber S
J IMMUNOL. 2023;211(11):1669-1679.

Fate mapping reveals compartment-specific clonal expansion of mononuclear phagocytes during kidney disease
Yin J, Mei Q, Prinz M, Abdullah Z, Panzer U, Li J, von Vietinghoff S, Kurts C
KIDNEY INT. 2023;104(3):605-610.

Tissue-resident memory T cells in the kidney
Asada N, Ginsberg P, Gagliani N, Mittrücker H, Panzer U
SEMIN IMMUNOPATHOL. 2022;44(6):801-811.

Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection
Bartsch P, Kilian C, Hellmig M, Paust H, Borchers A, Sivayoganathan A, Enk L, Zhao Y, Shaikh N, Büttner H, Wong M, Puelles V, Wiech T, Flavell R, Huber T, Turner J, Bonn S, Huber S, Gagliani N, Mittrücker H, Rohde H, Panzer U, Krebs C
PLOS PATHOG. 2022;18(4):e1010430.

Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis
Rickassel C, Gnirck A, Shaikh N, Adamiak V, Waterhölter A, Tanriver Y, Neumann K, Huber T, Gasteiger G, Panzer U, Turner J
J IMMUNOL. 2022;208(7):1585-1594.

Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis
Brede K, Schmid J, Steinmetz O, Panzer U, Klinge S, Mittrücker H
IMMUNOL LETT. 2021;236:51-60.

Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells
Koyro T, Kraus E, Lunemann S, Hölzemer A, Wulf S, Jung J, Fittje P, Henseling F, Körner C, Huber T, Grundhoff A, Wiech T, Panzer U, Fischer N, Altfeld M
KIDNEY INT. 2021;99(5):1140-1148.

Tissue-specific therapy in immune-mediated kidney diseases: new ARGuments for targeting the IL-23/IL-17 axis
Krebs C, Turner J, Riedel J, Panzer U
J CLIN INVEST. 2021;131(12):.

Immune-mediated glomerular diseases: new basic concepts and clinical implications
Panzer U, Huber T
CELL TISSUE RES. 2021;385(2):277-279.

T helper cell trafficking in autoimmune kidney diseases
Riedel J, Turner J, Panzer U
CELL TISSUE RES. 2021;385(2):281-292.

Kreatininanstieg, Fieber und Hämoptysen: „Double trouble“: „Double trouble“
Riedel J, Wiech T, Krebs C, Panzer U
NEPHROLOGE. 2021;16(6):386-390.

IL-17 receptor c signaling controls CD4⁺T_H17 immune responses and tissue injury in immune-mediated kidney diseases
Schmidt T, Luebbe J, Kilian C, Riedel J, Hiekmann S, Asada N, Ginsberg P, Robben L, Song N, Kaffke A, Peters A, Borchers A, Flavell R, Gagliani N, Pelzcar P, Huber S, Huber T, Turner J, Paust H, Krebs C, Panzer U
J AM SOC NEPHROL. 2021;32(12):3081-3098.

A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan L, Fichtner A, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs C, Ravens S, Prinz I
SCI IMMUNOL. 2021;6(58):.

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.

Single-cell biology to decode the immune cellular composition of kidney inflammation.
Zhao Y, Panzer U, Bonn S, Krebs C
CELL TISSUE RES. 2021;385(2):435-443.

Deep learning-based molecular morphometrics for kidney biopsies
Zimmermann M, Klaus M, Wong M, Thebille A, Gernhold L, Kuppe C, Halder M, Kranz J, Wanner N, Braun F, Wulf S, Wiech T, Panzer U, Krebs C, Hoxha E, Kramann R, Huber T, Bonn S, Puelles V
JCI INSIGHT. 2021;6(7):e144779.

Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease
Krebs C, Reimers D, Zhao Y, Paust H, Bartsch P, Nuñez S, Rosemblatt M, Hellmig M, Kilian C, Borchers A, Enk L, Zinke M, Becker M, Schmid J, Klinge S, Wong M, Puelles V, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer M, Cohen C, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner J, Riedel J, Huber S, Gagliani N, Huber T, Wiech T, Rohde H, Bono M, Bonn S, Panzer U, Mittrücker H
SCI IMMUNOL. 2020;5(50):.

Kidney dendritic cells: fundamental biology and functional roles in health and disease
Kurts C, Ginhoux F, Panzer U
NAT REV NEPHROL. 2020;16(7):391-407.

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells
Melderis S, Hagenstein J, Warkotsch M, Dang J, Herrnstadt G, Niehus C, Neumann K, Panzer U, Berasain C, Avila M, Tharaux P, Tiegs G, Steinmetz O
J AM SOC NEPHROL. 2020;31(9):1996-2012.

IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology
Nies J, Panzer U
FRONT IMMUNOL. 2020;11:341.

After ten years of follow-up, no difference between supportive care plus immunosuppression and supportive care alone in IgA nephropathy
Rauen T, Wied S, Fitzner C, Eitner F, Sommerer C, Zeier M, Otte B, Panzer U, Budde K, Benck U, Mertens P, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann J, Hilgers R, Floege J
KIDNEY INT. 2020;98(4):1044-1052.

Neutrophil Gelatinase-Associated Lipocalin Protects from ANCA-Induced GN by Inhibiting TH17 Immunity
Schreiber A, Rousselle A, Klocke J, Bachmann S, Popovic S, Bontscho J, Schmidt-Ott K, Siffrin V, Jerke U, Ashraf M, Panzer U, Kettritz R
J AM SOC NEPHROL. 2020;31(7):1569-1584.

Interleukin-9 protects from early podocyte injury and progressive glomerulosclerosis in Adriamycin-induced nephropathy
Xiong T, Attar M, Gnirck A, Wunderlich M, Becker M, Rickassel C, Puelles V, Meyer-Schwesinger C, Wiech T, Nies J, Divivier M, Fuchs T, Schulze Zur Wiesch J, Taipaleenmäki H, Hoxha E, Wirtz S, Huber T, Panzer U, Turner J
KIDNEY INT. 2020;98(3):615-629.

Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T cell responses
Breda P, Wiech T, Meyer-Schwesinger C, Grahammer F, Huber T, Panzer U, Tiegs G, Neumann K
AM J PHYSIOL-RENAL. 2019;317(1):F77-F89.

Endogenous IL-22 is dispensable for experimental glomerulonephritis
Gnirck A, Wunderlich M, Becker M, Xiong T, Weinert E, Meyer-Schwesinger C, Dumoutier L, Renauld J, Huber S, Panzer U, Turner J
AM J PHYSIOL-RENAL. 2019;316(4):F712-F722.

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury
Grigorieva I, Oszwald A, Grigorieva E, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer M, Cohen C, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker R, Rees A, Kain R
J AM SOC NEPHROL. 2019;30(9):1641-1658.

Role of regulatory T cells in experimental autoimmune glomerulonephritis
Klinge S, Yan K, Reimers D, Brede K, Schmid J, Paust H, Krebs C, Panzer U, Hopfer H, Mittrücker H
AM J PHYSIOL-RENAL. 2019;316(3):F572-F581.

The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis
Neumann K, Ostmann A, Breda P, Ochel A, Tacke F, Paust H, Panzer U, Tiegs G
SCI REP-UK. 2019;9:2038.

Infektiöse Glomerulonephritis
Panzer U
2019. Referenz Nephrologie. Alscher M (Hrsg.). 1. Aufl. Thieme Deutschlnad, 282-287.

Organisation of lymphocytic infiltrates in ANCA-associated glomerulonephritis
Brix S, Noriega M, Herden E, Goldmann B, Langbehn U, Busch M, Jabs W, Steinmetz O, Panzer U, Huber T, Stahl R, Wiech T
HISTOPATHOLOGY. 2018;72(7):1093-1101.

Development and validation of a renal risk score in ANCA-associated glomerulonephritis
Brix S, Noriega M, Tennstedt P, Vettorazzi E, Busch M, Nitschke M, Jabs W, Özcan F, Wendt R, Hausberg M, Sellin L, Panzer U, Huber T, Waldherr R, Hopfer H, Stahl R, Wiech T
KIDNEY INT. 2018;94(6):1177-1188.

T cell-derived IFN-γ downregulates protective group 2 innate lymphoid cells in murine lupus erythematosus
Düster M, Becker M, Gnirck A, Wunderlich M, Panzer U, Turner J
EUR J IMMUNOL. 2018;48(8):1364-1375.

Plasticity and heterogeneity of Th17 in immune-mediated kidney diseases
Krebs C, Panzer U
J AUTOIMMUN. 2018;87:61-68.

IL-17C/IL-17 Receptor E Signaling in CD4 T Cells Promotes T17 Cell-Driven Glomerular Inflammation
Krohn S, Nies J, Kapffer S, Schmidt T, Riedel J, Kaffke A, Peters A, Steinmetz O, Krebs C, Turner J, Brix S, Paust H, Stahl R, Panzer U
J AM SOC NEPHROL. 2018;29(4):1210-1222.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3 Regulatory T Cells
Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber F, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell R, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S
J IMMUNOL. 2018;201(12):3558-3568.

Effects of Two Immunosuppressive Treatment Protocols for IgA Nephropathy
Rauen T, Fitzner C, Eitner F, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens P, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann J, Hilgers R, Floege J
J AM SOC NEPHROL. 2018;29(1):317-325.

Mechanisms and functions of IL-17 signaling in renal autoimmune diseases
Schmidt T, Paust H, Panzer U
MOL IMMUNOL. 2018;104:90-99.

Tissue-Resident Lymphocytes in the Kidney
Turner J, Becker M, Mittrücker H, Panzer U
J AM SOC NEPHROL. 2018;29(2):389-399.

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Ergen C, Heymann F, Al Rawashdeh W, Gremse F, Bartneck M, Panzer U, Pola R, Pechar M, Storm G, Mohr N, Barz M, Zentel R, Kiessling F, Trautwein C, Lammers T, Tacke F
BIOMATERIALS. 2017;114:106-120.

A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease
Haase R, Potthoff S, Meyer-Schwesinger C, Frosch C, Wiech T, Panzer U, Königshausen E, Stegbauer J, Sellin L, Rump L, Quack I, Woznowski M
PLOS ONE. 2017;12(6):e0179217.

An Indirect Immunofluorescence Method Facilitates Detection of Thrombospondin Type 1 Domain-Containing 7A-Specific Antibodies in Membranous Nephropathy
Hoxha E, Beck L, Wiech T, Tomas N, Probst C, Mindorf S, Meyer-Schwesinger C, Zahner G, Stahl P, Schöpper R, Panzer U, Harendza S, Helmchen U, Salant D, Stahl R
J AM SOC NEPHROL. 2017;28(2):520-531.

Host DNases prevent vascular occlusion by neutrophil extracellular traps
Jiménez-Alcázar M, Rangaswamy C, Panda R, Bitterling J, Simsek Y, Long A, Bilyy R, Krenn V, Renné C, Renné T, Kluge S, Panzer U, Mizuta R, Mannherz H, Kitamura D, Herrmann M, Napirei M, Fuchs T
SCIENCE. 2017;358(6367):1202-1206.

T helper type 17 cells in immune-mediated glomerular disease
Krebs C, Schmidt T, Riedel J, Panzer U
NAT REV NEPHROL. 2017;13(10):647-659.

T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN
Nosko A, Kluger M, Diefenhardt P, Melderis S, Wegscheid C, Tiegs G, Stahl R, Panzer U, Steinmetz O
J AM SOC NEPHROL. 2017;28(1):185-196.

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis
Riedel J, Becker M, Kopp K, Düster M, Brix S, Meyer-Schwesinger C, Kluth L, Gnirck A, Attar M, Krohn S, Fehse B, Stahl R, Panzer U, Turner J
J AM SOC NEPHROL. 2017;28(7):2068-2080.

ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap
Anders H, Rovin B, Jayne D, Brunetta P, Coppo R, Davidson A, Devarapu S, de Zeeuw D, Duffield J, Eulberg D, Fierro A, Floege J, Frese S, Guillevin L, Holdsworth S, Hughes J, Kettritz R, Kluger M, Krebs C, Lapteva L, Levin A, Li J, Lightstone L, Mack M, Mansouri L, McAdoo S, McKinney E, Panzer U, Parikh S, Pusey C, Putterman C, Rabelink T, Radbruch A, Rees A, Reilly M, Reinders M, Remuzzi G, Ruggenenti P, Sacks S, Schall T, Meyer-Schwesinger C, Sharma K, Suzuki Y, Tomas N, Zhao M
KIDNEY INT REP. 2016;1(4):327-339.

CD103+ Kidney Dendritic Cells Protect against Crescentic GN by Maintaining IL-10-Producing Regulatory T Cells
Evers B, Engel D, Böhner A, Tittel A, Krause T, Heuser C, Garbi N, Kastenmüller W, Mack M, Tiegs G, Panzer U, Boor P, Ludwig-Portugall I, Kurts C
J AM SOC NEPHROL. 2016;27(11):3368-3382.

Inhibitor of NFκB Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN
Gotot J, Piotrowski E, Otte M, Tittel A, Linlin G, Yao C, Ziegelbauer K, Panzer U, Garbi N, Kurts C, Thaiss F
J AM SOC NEPHROL. 2016;27(7):1917-24.

A Mechanism for Cancer-Associated Membranous Nephropathy
Hoxha E, Wiech T, Stahl P, Zahner G, Tomas N, Meyer-Schwesinger C, Wenzel U, Janneck M, Steinmetz O, Panzer U, Harendza S, Stahl R
NEW ENGL J MED. 2016;374(20):1995-6.

Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus
Kluger M, Melderis S, Nosko A, Goerke B, Luig M, Meyer M, Turner J, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Stahl R, Panzer U, Steinmetz O
KIDNEY INT. 2016;89(1):158-166.

RORγt+Foxp3+ Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GN
Kluger M, Meyer M, Nosko A, Goerke B, Luig M, Wegscheid C, Tiegs G, Stahl R, Panzer U, Steinmetz O
J AM SOC NEPHROL. 2016;27(2):454-465.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
Krebs C, Paust H, Krohn S, Koyro T, Brix S, Riedel J, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch C, Mittrücker H, Steinhoff U, Stockinger B, Perez L, Wenzel U, Janneck M, Steinmetz O, Gagliani N, Stahl R, Huber S, Turner J, Panzer U
IMMUNITY. 2016;45(5):1078-1092.

Plasticity of Th17 Cells in Autoimmune Kidney Diseases
Krebs C, Turner J, Paust H, Kapffer S, Koyro T, Krohn S, Ufer F, Friese M, Flavell R, Stockinger B, Steinmetz O, Stahl R, Huber S, Panzer U
J IMMUNOL. 2016;197(2):449-57.

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN
Paust H, Riedel J, Krebs C, Turner J, Brix S, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein S, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker H, Steinmetz O, Stahl R, Panzer U
J AM SOC NEPHROL. 2016;27(7):1933-42.

IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases
Riedel J, Paust H, Krohn S, Turner J, Kluger M, Steinmetz O, Krebs C, Stahl R, Panzer U
J AM SOC NEPHROL. 2016;27(12):3666-3677.

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN
Brix S, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira S, Tacke F, Wolf G, Busch M, Jabs W, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl R
J AM SOC NEPHROL. 2015;26(9):2105-2117.

CXCL5 drives neutrophil recruitment in TH17-mediated GN
Disteldorf E, Krebs C, Paust H, Turner J, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz O, Peters A, Bennstein S, Kaffke A, Llanto C, Lira S, Mittrücker H, Stahl R, Kurts C, Kaufmann S, Panzer U
J AM SOC NEPHROL. 2015;26(1):55-66.

Glomerulopathy Induced by Immunization with a Peptide Derived from the Goodpasture Antigen α3IV-NC1
Hopfer H, Hünemörder S, Treder J, Turner J, Paust H, Meyer-Schwesinger C, Hopfer U, Sachs M, Peters A, Bucher-Kocaoglu B, Ahrens S, Panzer U, Mittrücker H
J IMMUNOL. 2015;194(8):3646-55.

Spontaneous remission of proteinuria is a frequent event in phospholipase A2 receptor antibody-negative patients with membranous nephropathy
Hoxha E, Harendza S, Pinnschmidt H, Tomas N, Helmchen U, Panzer U, Stahl R
NEPHROL DIAL TRANSPL. 2015;30(11):1862-1869.

TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis
Hünemörder S, Treder J, Ahrens S, Schumacher V, Paust H, Menter T, Matthys P, Kamradt T, Meyer-Schwesinger C, Panzer U, Hopfer H, Mittrücker H
J PATHOL. 2015;237(1):62-71.

MicroRNA-193a Regulates the Transdifferentiation of Human Parietal Epithelial Cells toward a Podocyte Phenotype
Kietzmann L, Guhr S, Meyer T, Ni L, Sachs M, Panzer U, Stahl R, Saleem M, Kerjaschki D, Gebeshuber C, Meyer-Schwesinger C
J AM SOC NEPHROL. 2015;26(6):1389-1401.

Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN
Luig M, Kluger M, Goerke B, Meyer M, Nosko A, Yan I, Scheller J, Mittrücker H, Rose-John S, Stahl R, Panzer U, Steinmetz O
J AM SOC NEPHROL. 2015;26(7):1597-1607.

Intensive Supportive Care plus Immunosuppression in IgA Nephropathy
Rauen T, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens P, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann J, Hilgers R, Floege J
NEW ENGL J MED. 2015;373(23):2225-36.

Function of the Th17/interleukin-17A immune response in murine lupus nephritis
Schmidt T, Paust H, Krebs C, Turner J, Kaffke A, Bennstein S, Koyro T, Peters A, Velden J, Hünemörder S, Haag F, Steinmetz O, Mittrücker H, Stahl R, Panzer U
ARTHRITIS RHEUMATOL. 2015;67(2):475-87.

The Function of the Chemokine Receptor CXCR6 in the T Cell Response of Mice against Listeria monocytogenes
Heesch K, Raczkowski F, Schumacher V, Hünemörder S, Panzer U, Mittrücker H
PLOS ONE. 2014;9(5):e97701.

M-type phospholipase A2 receptor autoantibodies and renal function in patients with primary membranous nephropathy
Hoxha E, Harendza S, Pinnschmidt H, Panzer U, Stahl R
CLIN J AM SOC NEPHRO. 2014;9(11):1883-1890.

PLA2R Antibody Levels and Clinical Outcome in Patients with Membranous Nephropathy and Non-Nephrotic Range Proteinuria under Treatment with Inhibitors of the Renin-Angiotensin System
Hoxha E, Harendza S, Pinnschmidt H, Panzer U, Stahl R
PLOS ONE. 2014;9(10):e110681.

Phospholipase A2 receptor autoantibodies and clinical outcome in patients with primary membranous nephropathy
Hoxha E, Thiele I, Zahner G, Panzer U, Harendza S, Stahl R
J AM SOC NEPHROL. 2014;25(6):1357-1366.

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
Kiryluk K, Li Y, Scolari F, Sanna-Cherchi S, Choi M, Verbitsky M, Fasel D, Lata S, Prakash S, Shapiro S, Fischman C, Snyder H, Appel G, Izzi C, Viola B, Dallera N, Del Vecchio L, Barlassina C, Salvi E, Bertinetto F, Amoroso A, Savoldi S, Rocchietti M, Amore A, Peruzzi L, Coppo R, Salvadori M, Ravani P, Magistroni R, Ghiggeri G, Caridi G, Bodria M, Lugani F, Allegri L, Delsante M, Maiorana M, Magnano A, Frasca G, Boer E, Boscutti G, Ponticelli C, Mignani R, Marcantoni C, Di Landro D, Santoro D, Pani A, Polci R, Feriozzi S, Chicca S, Galliani M, Gigante M, Gesualdo L, Zamboli P, Battaglia G, Garozzo M, Maixnerová D, Tesar V, Eitner F, Rauen T, Floege J, Kovacs T, Nagy J, Mucha K, Pączek L, Zaniew M, Mizerska-Wasiak M, Roszkowska-Blaim M, Pawlaczyk K, Gale D, Barratt J, Thibaudin L, Berthoux F, Canaud G, Boland A, Metzger M, Panzer U, Suzuki H, Goto S, Narita I, Caliskan Y, Xie J, Hou P, Chen N, Zhang H, Wyatt R, Novak J, Julian B, Feehally J, Stengel B, Cusi D, Lifton R, Gharavi A
NAT GENET. 2014;46(11):1187-96.

Stat3 Programs Th17-Specific Regulatory T Cells to Control GN
Kluger M, Luig M, Wegscheid C, Goerke B, Paust H, Brix S, Yan I, Mittrücker H, Hagl B, Renner E, Tiegs G, Wiech T, Stahl R, Panzer U, Steinmetz O
J AM SOC NEPHROL. 2014;25(6):1291-302.

B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis
Kluger M, Ostmann A, Luig M, Meyer M, Goerke B, Paust H, Meyer-Schwesinger C, Stahl R, Panzer U, Tiegs G, Steinmetz O
EUR J IMMUNOL. 2014;44(3):683-693.

Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension
Krebs C, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl R, Benndorf R, Velden J, Paust H, Panzer U, Ehmke H, Wenzel U
HYPERTENSION. 2014;63(3):565-71.

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium
Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl J, Maurice N, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse M, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne H, Garbi N, Kastenmüller W, Knolle P, Kurts C, Engel D
CELL. 2014;156(3):456-468.

Neuropsychological outcome after complicated Shiga toxin-producing Escherichia coli infection
Simova O, Weineck G, Schütze T, Wegscheider K, Panzer U, Stahl R, Gerloff C, Magnus T
PLOS ONE. 2014;9(7):e103029.

Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome
Braune S, Wichmann D, Heinz M, Nierhaus A, Becker H, Meyer T, Meyer G, Müller-Schulz M, Fricke J, de Weerth A, Höpker W, Fiehler J, Magnus T, Gerloff C, Panzer U, Stahl R, Wegscheider K, Kluge S
CRIT CARE MED. 2013;41(7):1702-10.

Is there a role for proximal tubular cells in regulating dendritic cell maturation and function in renal disease?
Disteldorf E, Panzer U
NEPHROL DIAL TRANSPL. 2013;28(2):239-41.

Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression
Hochheiser K, Heuser C, Krause T, Teteris S, Ilias A, Weisheit C, Hoss F, Tittel A, Knolle P, Panzer U, Engel D, Tharaux P, Kurts C
J CLIN INVEST. 2013;123(10):4242-54.

Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis
Kluger M, Zahner G, Paust H, Schaper M, Magnus T, Panzer U, Stahl R
KIDNEY INT. 2013;83(5):865-77.

MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN
Krebs C, Kapffer S, Paust H, Schmidt T, Bennstein S, Peters A, Stege G, Brix S, Meyer-Schwesinger C, Müller R, Turner J, Steinmetz O, Wolf G, Stahl R, Panzer U
J AM SOC NEPHROL. 2013;24(12):1955-65.

The immune system and kidney disease: basic concepts and clinical implications
Kurts C, Panzer U, Anders H, Rees A
NAT REV IMMUNOL. 2013;13(10):738-53.

Regulatory T Cell-Derived IL-10 Ameliorates Crescentic GN.
Ostmann A, Paust H, Panzer U, Wegscheid C, Kapffer S, Huber S, Flavell R, Erhardt A, Tiegs G
J AM SOC NEPHROL. 2013;24(6):930-942.

IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation
Turner J, Morrison P, Wilhelm C, Wilson M, Ahlfors H, Renauld J, Panzer U, Helmby H, Stockinger B
J EXP MED. 2013;210(13):2951-65.

Characterization of the renal CD4(+) T-cell response in experimental autoimmune glomerulonephritis.
Hopfer H, Holzer J, Hünemörder S, Paust H, Sachs M, Meyer-Schwesinger C, Turner J, Panzer U, Mittrücker H
KIDNEY INT. 2012;82(1):60-71.

Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy.
Hoxha E, Kneißler U, Stege G, Zahner G, Thiele I, Panzer U, Harendza S, Helmchen U, Stahl R
KIDNEY INT. 2012;82(7):797-804.

CCR5 deficiency does not reduce hypertensive end-organ damage in mice
Krebs C, Fraune C, Schmidt-Haupt R, Turner J, Panzer U, Quang M, Tannapfel A, Velden J, Stahl R, Wenzel U
AM J HYPERTENS. 2012;25(4):479-486.

Glomerulonephritiden – Genetische Aspekte
Krebs C, Panzer U
Dialyse aktuell. 2012;16(9):523-527.

The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak.
Magnus T, Röther J, Simova O, Meier-Cillien M, Repenthin J, Möller F, Gbadamosi J, Panzer U, Wengenroth M, Hagel C, Kluge S, Stahl R, Wegscheider K, Urban P, Eckert B, Glatzel M, Fiehler J, Gerloff C
BRAIN. 2012;135(Pt 6):1850-1859.

Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis.
Paust H, Turner J, Riedel J, Disteldorf E, Peters A, Schmidt T, Krebs C, Velden J, Mittrücker H, Steinmetz O, Stahl R, Panzer U
KIDNEY INT. 2012;82(1):72-83.

Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.
Riedel J, Paust H, Turner J, Tittel A, Krebs C, Disteldorf E, Wegscheid C, Tiegs G, Velden J, Mittrücker H, Garbi N, Stahl R, Steinmetz O, Kurts C, Panzer U
J AM SOC NEPHROL. 2012;23(12):1987-2000.

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner J, Krebs C, Tittel A, Paust H, Meyer-Schwesinger C, Bennstein S, Steinmetz O, Prinz I, Magnus T, Korn T, Stahl R, Kurts C, Panzer U
J AM SOC NEPHROL. 2012;23(9):1486-1495.

Protective role for CCR5 in murine lupus nephritis.
Turner J, Paust H, Mathey S, Bramke P, Krebs C, Steinmetz O, Velden J, Haag F, Stahl R, Panzer U
AM J PHYSIOL-RENAL. 2012;302(11):1503-1515.

Renal IL-17 expression in human ANCA-associated glomerulonephritis.
Velden J, Paust H, Hoxha E, Turner J, Steinmetz O, Wolf G, Jabs W, Özcan F, Beige J, Heering P, Schröder S, Kneißler U, Disteldorf E, Mittrücker H, Stahl R, Helmchen U, Panzer U
AM J PHYSIOL-RENAL. 2012;302(12):1663-1673.

CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.
Erhardt A, Wegscheid C, Claaß B, Carambia A, Herkel J, Mittrücker H, Panzer U, Tiegs G
J IMMUNOL. 2011;186(9):5284-5293.

Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.
Hochheiser K, Engel D, Hammerich L, Heymann F, Knolle P, Panzer U, Kurts C
J AM SOC NEPHROL. 2011;22(2):306-316.

An immunofluorescence test for phospholipase-A₂-receptor antibodies and its clinical usefulness in patients with membranous glomerulonephritis.
Hoxha E, Harendza S, Zahner G, Panzer U, Steinmetz O, Fechner K, Helmchen U, Stahl R
NEPHROL DIAL TRANSPL. 2011;26(8):2526-2532.

ISN Forefronts Symposium 2010 in Sylt, Germany: 'Induction and Resolution of Renal Inflammation'
Panzer U, Turner J, Steinmetz O, Kurts C, Johnson R, Stahl R
KIDNEY INT. 2011;79(8):807-813.

Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
Paust H, Ostmann A, Erhardt A, Turner J, Velden J, Mittrücker H, Sparwasser T, Panzer U, Tiegs G
KIDNEY INT. 2011;80(2):154-164.

T cell cross-talk with kidney dendritic cells in glomerulonephritis.
Panzer U, Kurts C
J MOL MED. 2010;88(1):19-26.

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.
Semmling V, Lukacs-Kornek V, Thaiss C, Quast T, Hochheiser K, Panzer U, Rossjohn J, Perlmutter P, Cao J, Godfrey D, Savage P, Knolle P, Kolanus W, Förster I, Kurts C
NAT IMMUNOL. 2010;11(4):313-320.

Staying on top of things right from the start: the obsessive-compulsive disorder of regulatory T cells.
Steinmetz O, Turner J, Panzer U
J AM SOC NEPHROL. 2010;21(1):6-7.

The Th17 immune response in renal inflammation.
Turner J, Paust H, Steinmetz O, Panzer U
KIDNEY INT. 2010;77(12):1070-1075.

CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Turner J, Paust H, Steinmetz O, Peters A, Riedel J, Erhardt A, Wegscheid C, Velden J, Fehr S, Mittrücker H, Tiegs G, Stahl R, Panzer U
J AM SOC NEPHROL. 2010;21(6):974-985.

Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury.
Heymann F, Meyer-Schwesinger C, Hamilton-Williams E, Hammerich L, Panzer U, Kaden S, Quaggin S, Floege J, Gröne H, Kurts C
J CLIN INVEST. 2009;119(5):1286-1297.

Resolution of renal inflammation: a new role for NF-kappaB1 (p50) in inflammatory kidney diseases.
Panzer U, Steinmetz O, Turner J, Meyer-Schwesinger C, von Ruffer C, Meyer T, Zahner G, Gómez-Guerrero C, Schmid R, Helmchen U, Moeckel G, Wolf G, Stahl R, Thaiss F
AM J PHYSIOL-RENAL. 2009.

The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis.
Paust H, Turner J, Steinmetz O, Peters A, Heymann F, Hölscher C, Wolf G, Kurts C, Mittrücker H, Stahl R, Panzer U
J AM SOC NEPHROL. 2009;20(5):969-979.

Chemokines and B cells in renal inflammation and allograft rejection.
Steinmetz O, Stahl R, Panzer U
FRONT BIOSCI-LANDMRK. 2009;1:13-22.

CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.
Steinmetz O, Turner J, Paust H, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer T, Helmchen U, Mittrücker H, Stahl R, Panzer U
J IMMUNOL. 2009;183(7):4693-4704.

Prostaglandin EP2 and EP4 receptors modulate CCL2 (MCP-1) expression in response to LPS-induced renal glomerular inflammation.
Zahner G, Schaper M, Panzer U, Kluger M, Stahl R, Thaiss F, Schneider A
BIOCHEM J. 2009.

Prostaglandin EP2 and EP4 receptors modulate expression of the chemokine CCL2 (MCP-1) in response to LPS-induced renal glomerular inflammation
Zahner G, Schaper M, Panzer U, Kluger M, Stahl R, Thaiss F, Schneider A
BIOCHEM J. 2009;422(3):563-70.

15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells
Panzer U, Zahner G, Wienberg U, Steinmetz O, Peters A, Turner J, Paust H, Wolf G, Stahl R, Schneider A
NEPHROL DIAL TRANSPL. 2008;23(12):3776-85.

Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritis.
Steinmetz O, Velden J, Kneissler U, Marx M, Klein A, Helmchen U, Stahl R, Panzer U
KIDNEY INT. 2008;74(4):448-457.

CCR5 deficiency aggravates crescentic glomerulonephritis in mice.
Turner J, Paust H, Steinmetz O, Peters A, Meyer-Schwesinger C, Heymann F, Helmchen U, Fehr S, Horuk R, Wenzel U, Kurts C, Mittrücker H, Stahl R, Panzer U
J IMMUNOL. 2008;181(9):6546-6556.

PDGF-B gene single-nucleotide polymorphisms are not predictive for disease onset or progression of IgA nephropathy.
Bicanski B, Wenderdel M, Mertens P, Senderek J, Panzer U, Steinmetz O, Stahl R, Cerullo G, Diletta Torres D, Schena F, Zerres K, Floege J
CLIN NEPHROL. 2007;67(2):65-72.

Chemokine receptor CXCR3 mediates T cell recruitment and tissue injury in nephrotoxic nephritis in mice.
Panzer U, Steinmetz O, Paust H, Meyer-Schwesinger C, Peters A, Turner J, Zahner G, Heymann F, Kurts C, Hopfer H, Helmchen U, Haag F, Schneider A, Stahl R
J AM SOC NEPHROL. 2007;18(7):2071-2084.

Acute cellular allograft rejection in homozygous CCR5 Delta32 patients after renal transplantation.
Steinmetz O, Fischereder M, Weiss M, Helmchen U, Stahl R, Panzer U
TRANSPLANTATION. 2007;84(4):559-561.

Rituximab removes intrarenal B cell clusters in patients with renal vascular allograft rejection.
Steinmetz O, Lange-Hüsken F, Turner J, Vernauer A, Helmchen U, Stahl R, Thaiss F, Panzer U
TRANSPLANTATION. 2007;84(7):842-850.

A pitfall of glomerular sieving: profibrotic and matrix proteins derive from the Bowman's capsule and not the glomerular tuft in rats with renovascular hypertension.
Steinmetz O, Panzer U, Fehr S, Meyer-Schwesinger C, Stahl R, Wenzel U
NEPHROL DIAL TRANSPL. 2007;22(10):3055-3060.

Antihypertensive therapy induces compartment-specific chemokine expression and a Th1 immune response in the clipped kidney of Goldblatt hypertensive rats.
Steinmetz O, Sadaghiani S, Panzer U, Krebs C, Meyer-Schwesinger C, Streichert T, Fehr S, Hamming I, van Goor H, Stahl R, Wenzel U
AM J PHYSIOL-RENAL. 2007;292(2):876-887.

Formation of lymphoid-like tissue in the kidney--is there a role for chemokines?
Steinmetz O, Stahl R, Panzer U
NEPHROL DIAL TRANSPL. 2007;22(2):350-352.

Targeting of Th1-associated chemokine receptors CXCR3 and CCR5 as therapeutic strategy for inflammatory diseases.
Turner J, Steinmetz O, Stahl R, Panzer U
MINI-REV MED CHEM. 2007;7(11):1089-1096.

Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1.
Jafari C, Panzer U, Steinmetz O, Zahner G, Stahl R, Harendza S
CELL MOL BIOL LETT. 2006;11(3):424-437.

Compartment-specific expression and function of the chemokine IP-10/CXCL10 in a model of renal endothelial microvascular injury.
Panzer U, Steinmetz O, Reinking R, Meyer T, Fehr S, Schneider A, Zahner G, Wolf G, Helmchen U, Schaerli P, Stahl R, Thaiss F
J AM SOC NEPHROL. 2006;17(2):454-464.

Kidney diseases and chemokines.
Panzer U, Steinmetz O, Stahl R, Wolf G
CURR DRUG TARGETS. 2006;7(1):65-80.

Statin therapy in patients with chronic kidney disease: to use or not to use.
Steinmetz O, Panzer U, Stahl R, Wenzel U
EUR J CLIN INVEST. 2006;36(8):519-527.

The chemokine receptor 5 Delta32 mutation is associated with increased renal survival in patients with IgA nephropathy.
Panzer U, Schneider A, Steinmetz O, Wenzel U, Barth P, Reinking R, Becker J, Harendza S, Zahner G, Fischereder M, Krämer B, Krämer B, Schlöndorff D, Ostendorf T, Floege J, Helmchen U, Stahl R
KIDNEY INT. 2005;67(1):75-81.

BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection.
Steinmetz O, Panzer U, Kneissler U, Harendza S, Lipp M, Helmchen U, Stahl R
KIDNEY INT. 2005;67(4):1616-1621.

Letzte Aktualisierung aus dem FIS: 20.12.2024 - 23:32 Uhr