2024

Using a combination of cognitive behavioral therapy, case management and eHealth components for patients with depression or panic disorders in primary care practices in Hesse, Germany: an exploration of healthcare professionals’ lived experiences
Hanf M, Körner C, Lukaschek K, Gensichen J, Lezius S, Zapf A, Heider D, König H, Hansen S, van den Akker M
BMC Digital Health. 2024;2:.

A multi-center interventional study to assess pharmacokinetics, effectiveness, and tolerability of prolonged-release tacrolimus after pediatric kidney transplantation: study protocol for a prospective, open-label, randomized, two-phase, two-sequence, single dose, crossover, phase III b trial
Karaterzi S, Tönshoff B, Ahlenstiel-Grunow T, Baghai M, Beck B, Büscher A, Eifler L, Giese T, Lezius S, Müller C, Oh J, Zapf A, Weber L, Pape L
Frontiers in nephrology. 2024;4:.

Impact of telemedical management on hospitalization and mortality in heart failure patients with diabetes: a post-hoc subgroup analysis of the TIM-HF2 trial
Koehler F, Koehler J, Bramlage P, Vettorazzi E, Wegscheider K, Lezius S, Spethmann S, Iakoubov R, Vijayan A, Winkler S, Melzer C, Schütt K, Dessapt-Baradez C, Paar W, Koehler K, Müller-Wieland D
CARDIOVASC DIABETOL. 2024;23(1):198.

Favorable Outcome After Single-kidney Transplantation From Small Donors in Children: A Match-controlled CERTAIN Registry Study
Schild R, Carvajal Abreu K, Büscher A, Kanzelmeyer N, Lezius S, Krupka K, Weitz M, Prytula A, Printza N, Berta L, Saygılı S, Sellier-Leclerc A, Spartà G, Marks S, König S, Topaloglu R, Klaus G, Weber S, Oh J, Herden U, Carraro A, Dello Strologo L, Ariceta G, Hoyer P, Tönshoff B, Pape L
TRANSPLANTATION. 2024;108(8):1793-1801.

2023

Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence
Baach F, Meyer B, Oh J, Lezius S, Böger R, Schwedhelm E, Choe C, Neu A
AMINO ACIDS. 2023;55(10):1381-1388.

Effects of Remote Patient Management on Self-Care Behaviour in Heart Failure Patients: Results from the randomised TIM-HF2 Trial
Deckwart O, Koehler K, Lezius S, Prescher S, Koehler F, Winkler S
EUR J CARDIOVASC NUR. 2023;22(8):786-794.

Combined Short-Pulse and Directional Deep Brain Stimulation of the Thalamic Ventral Intermediate Area for Essential Tremor
Hidding U, Lezius S, Schaper M, Buhmann C, Gerloff C, Pötter-Nerger M, Hamel W, Moll C, Choe C
NEUROMODULATION. 2023;26(8):1680-1688.

Disentangling pharmacological and expectation effects in antidepressant discontinuation among patients with fully remitted major depressive disorder: study protocol of a randomized, open-hidden discontinuation trial
Meißner C, Warren C, Fadai T, Müller A, Zapf A, Lezius S, Ozga A, Falkenberg I, Kircher T, Nestoriuc Y
BMC PSYCHIATRY. 2023;23(1):.

Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke
Schwieren L, Jensen M, Schulz R, Lezius S, Laxy E, Milatz M, Thomalla G, Böger R, Gerloff C, Magnus T, Schwedhelm E, Choe C
LIFE-BASEL. 2023;13(7):.

2022

Ten Years of Improving Acute Stroke Management in a Metropolitan Area: A Population-Based Quantification of Quality Indicators
Alegiani A, Rosenkranz M, Schmitz L, Lezius S, Seidel G, Heßelmann V, Töpper R, Terborg C, Urban P, Brüning R, Höltje J, Lienau F, Arning C, Marquardt L, Müller-Jensen A, Röther J, Eckert B, Zapf A, Fiehler J, Thomalla G, Gerloff C
EUR NEUROL. 2022;85(1):39-49.

Fra-2 overexpression upregulates pro-metastatic cell-adhesion molecules, promotes pulmonary metastasis, and reduces survival in a spontaneous xenograft model of human breast cancer
Arnold S, Kortland J, Maltseva D, Nersisyan S, Samatov T, Lezius S, Tonevitsky A, Milde-Langosch K, Wicklein D, Schumacher U, Stürken C
J CANCER RES CLIN. 2022;148(6):1525-1542.

The impact of pharmacists' interventions within the Closed Loop Medication Management process on medication safety: An analysis in a German university hospital
Berger V, Sommer C, Boje P, Hollmann J, Hummelt J, König C, Lezius S, van der Linde A, Marhenke C, Melzer S, Michalowski N, Baehr M, Langebrake C
FRONT PHARMACOL. 2022;13:.

Age-Adjusted Serum Neurofilament Predicts Cognitive Decline in Parkinson's Disease (MARK-PD)
Buhmann C, Lezius S, Pötter-Nerger M, Gerloff C, Kuhle J, Choe C
MOVEMENT DISORD. 2022;37(2):435-436.

Effectiveness of a complex regional advance care planning intervention to improve care consistency with care preferences
Götze K, Bausewein C, Feddersen B, Fuchs A, Hot A, Hummers E, Icks A, Kirchner Ä, Kleinert E, Klosterhalfen S, Kolbe H, Laag S, Langner H, Lezius S, Meyer G, Montalbo J, Nauck F, Reisinger C, Rieder N, Schildmann J, Schunk M, Stanze H, Vogel C, Wegscheider K, Zapf A, Marckmann G, in der Schmitten J
TRIALS. 2022;23(1):.

Natural history of MRI brain volumes in patients with neuronal ceroid lipofuscinosis 3: a sensitive imaging biomarker
Hochstein J, Schulz A, Nickel M, Lezius S, Grosser M, Fiehler J, Sedlacik J, Löbel U
NEURORADIOLOGY. 2022;64(10):2059-2067.

Left Ventricular Diastolic Dysfunction Is Not Associated With Pulmonary Edema in Septic Patients. A Prospective Observational Cohort Study
Kahl U, Schirren L, Yu Y, Lezius S, Fischer M, Menke M, Sinning C, Nierhaus A, Vens M, Zöllner C, Kluge S, Goepfert M, Roeher K
FRONT CARDIOVASC MED. 2022;9:.

Single-dose of adrecizumab versus placebo in acute cardiogenic shock (ACCOST-HH): an investigator-initiated, randomised, double-blinded, placebo-controlled, multicentre trial
Karakas M, Akin I, Burdelski C, Clemmensen P, Grahn H, Jarczak D, Keßler M, Kirchhof P, Landmesser U, Lezius S, Lindner D, Mebazaa A, Nierhaus A, Ocak A, Rottbauer W, Sinning C, Skurk C, Söffker G, Westermann D, Zapf A, Zengin E, Zeller T, Kluge S
LANCET RESP MED. 2022;10(3):247-254.

Clinical pharmacists' interventions across German hospitals: results from a repetitive cross-sectional study
Langebrake C, Hohmann C, Lezius S, Lueb M, Picksak G, Walter W, Kaden S, Hilgarth H, Ihbe-Heffinger A, Leichenberg K
INT J CLIN PHARM-NET. 2022;44(1):64-71.

Serum neurofilament light chain and postural instability/gait difficulty (PIGD) subtypes of Parkinson's disease in the MARK-PD study
Pötter-Nerger M, Dutke J, Lezius S, Buhmann C, Schulz R, Gerloff C, Kuhle J, Choe C
J NEURAL TRANSM. 2022;129(3):295-300.

Mandibular condyle morphology among patients with mucopolysaccharidosis: an observational study of panoramic radiographs
Schmid-Herrmann C, Muschol N, Fuhrmann V, Koehn A, Lezius S, Kahl-Nieke B, Koehne T
INT J PAEDIATR DENT. 2022;32(5):737-744.

Effective high-density lipoprotein cholesterol is associated with carotid intima-media thickness and vascular events after acute ischemic stroke
Schwedhelm E, Tiedt S, Lezius S, Wölfer T, Jensen M, Schulz R, Böger R, Gerloff C, Thomalla G, Choe C
ATHEROSCLEROSIS. 2022;357:9-13.

Validation of the German eHealth impact questionnaire for online health information users affected by multiple sclerosis
Sippel A, Riemann-Lorenz K, Pöttgen J, Wiedemann R, Drixler K, Bitzer E, Holmberg C, Lezius S, Heesen C
BMC MED INFORM DECIS. 2022;22(1):.

Diabetes, Glycated Hemoglobin (HbA1c), and Neuroaxonal Damage in Parkinson's Disease (MARK-PD Study)
Uyar M, Lezius S, Buhmann C, Pötter-Nerger M, Schulz R, Meier S, Gerloff C, Kuhle J, Choe C
MOVEMENT DISORD. 2022;37(6):1299-1304.

2021

Trajectories of Left Ventricular Ejection Fraction After Acute Decompensation for Systolic Heart Failure: Concomitant Echocardiographic and Systemic Changes, Predictors, and Impact on Clinical Outcomes
Albert J, Lezius S, Störk S, Morbach C, Güder G, Frantz S, Wegscheider K, Ertl G, Angermann C
J AM HEART ASSOC. 2021;10(3):e017822.

Impact of a multimedia website with patient experiences of multiple sclerosis (PExMS) on immunotherapy decision-making: study protocol for a pilot randomised controlled trial in a mixed-methods design
Barabasch A, Riemann-Lorenz K, Kofahl C, Scheiderbauer J, Eklund D, Kleiter I, Kasper J, Köpke S, Lezius S, Zapf A, Rahn A, Heesen C
PILOT FEASIBILITY ST. 2021;7(1):16.

Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations
Both A, Huang J, Qi M, Lausmann C, Weißelberg S, Büttner H, Lezius S, Failla A, Christner M, Stegger M, Gehrke T, Baig S, Citak M, Alawi M, Aepfelbacher M, Rohde H
PLOS PATHOG. 2021;17(2):e1009304.

Association of lipid levels with motor and cognitive function and decline in advanced Parkinson's disease in the Mark-PD study
Choe C, Petersen E, Lezius S, Cheng B, Schulz R, Buhmann C, Pötter-Nerger M, Daum G, Blankenberg S, Gerloff C, Schwedhelm E, Zeller T
PARKINSONISM RELAT D. 2021;85:5-10.

Serum neurofilament is associated with motor function, cognitive decline and subclinical cardiac damage in advanced Parkinson's disease (MARK-PD)
Niemann L, Lezius S, Maceski A, Leppert D, Englisch C, Schwedhelm E, Zeller T, Gerloff C, Kuhle J, Choe C
PARKINSONISM RELAT D. 2021;90:44-48.

The ability of the eating assessment tool-10 to detect penetration and aspiration in Parkinson's disease
Schlickewei O, Nienstedt J, Frank U, Fründt O, Pötter-Nerger M, Gerloff C, Buhmann C, Müller F, Lezius S, Koseki J, Pflug C
EUR ARCH OTO-RHINO-L. 2021;278(5):1661-1668.

Sphingosine-1-Phosphate, Motor Severity, and Progression in Parkinson's Disease (MARK-PD)
Schwedhelm E, Englisch C, Niemann L, Lezius S, von Lucadou M, Marmann K, Böger R, Peine S, Daum G, Gerloff C, Choe C
MOVEMENT DISORD. 2021;36(9):2178-2182.

Trimethyllysine, vascular risk factors and outcome in acute ischemic stroke (MARK-STROKE)
Schwedhelm E, von Lucadou M, Peine S, Lezius S, Thomalla G, Böger R, Gerloff C, Choe C
AMINO ACIDS. 2021;53(4):555-561.

HbA1c and Motor Outcome in Parkinson's Disease in the Mark-PD Study
Zittel S, Uyar M, Lezius S, Gerloff C, Choe C
MOVEMENT DISORD. 2021;36(8):1991-1992.

2020

Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently
Bergmann S, von Buenau B, Vidal-Y-Sy S, Haftek M, Wladykowski E, Houdek P, Lezius S, Duplan H, Bäsler K, Dähnhardt-Pfeiffer S, Gorzelanny C, Schneider S, Rodriguez E, Stölzl D, Weidinger S, Brandner J
SCI REP-UK. 2020;10(1):2024.

Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies
Choe C, Lezius S, Cordts K, Gerloff C, Böger R, Schwedhelm E, Grant P
NEUROL SCI. 2020;41(1):149-153.

Course of cervical intraepithelial neoplasia diagnosed during pregnancy
Grimm D, Lang I, Prieske K, Jaeger A, Müller V, Kuerti S, Burandt E, Lezius S, Schmalfeldt B, Woelber L
ARCH GYNECOL OBSTET. 2020;301(6):1503-1512.

Mortality and morbidity 1 year after stopping a remote patient management intervention: extended follow-up results from the telemedical interventional management in patients with heart failure II (TIM-HF2) randomised trial
Koehler F, Koehler K, Prescher S, Kirwan B, Wegscheider K, Vettorazzi E, Lezius S, Winkler S, Moeller V, Fiss G, Schleder J, Koehler M, Zugck C, Störk S, Butter C, Prondzinsky R, Spethmann S, Angermann C, Stangl V, Halle M, Haehling S, Dreger H, Stangl K, Deckwart O, Anker S
LANCET DIGIT HEALTH. 2020;2(1):e16 - e24.

2019

Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies
Cordts K, Grzybowski R, Lezius S, Lüneburg N, Atzler D, Neu A, Hornig S, Böger R, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant P, Choe C
J NEUROL SCI. 2019;397:156-161.

Obstructive sleep apnea and craniofacial appearance in MPS type I-Hurler children after hematopoietic stem cell transplantation
Koehne T, Müller-Stöver S, Köhn A, Stumpfe K, Lezius S, Schmid C, Lukacs Z, Kahl-Nieke B, Muschol N
SLEEP BREATH. 2019;23(4):1315-1321.

2018

Adaptive servo-ventilation for central sleep apnoea in systolic heart failure: results of the major substudy of SERVE-HF
Cowie M, Woehrle H, Wegscheider K, Vettorazzi E, Lezius S, Koenig W, Weidemann F, Smith G, Angermann C, d'Ortho M, Erdmann E, Levy P, Simonds A, Somers V, Zannad F, Teschler H
EUR J HEART FAIL. 2018;20(3):536-544.

The T-peak-to-T-end interval: a novel ECG marker for ventricular arrhythmia and appropriate ICD therapy in patients with hypertrophic cardiomyopathy
Dinshaw L, Münch J, Dickow J, Lezius S, Willems S, Hoffmann B, Patten M
CLIN RES CARDIOL. 2018;107(2):130-137.

Serum Biomarkers of Endothelial Dysfunction in Fabry Associated Cardiomyopathy
Loso J, Lund N, Avanesov M, Muschol N, Lezius S, Cordts K, Schwedhelm E, Patten M
FRONT CARDIOVASC MED. 2018;5:108.

Disease characteristics and progression in patients with late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease: an observational cohort study
Nickel M, Simonati A, Jacoby D, Lezius S, Kilian D, Van de Graaf B, Pagovich O, Kosofsky B, Yohay K, Downs M, Slasor P, Ajayi T, Crystal R, Kohlschütter A, Sondhi D, Schulz A
LANCET CHILD ADOLESC. 2018;2(8):582-590.

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival
Winkler M, Nierhaus A, Rösler G, Lezius S, Harlandt O, Schwedhelm E, Böger R, Kluge S
CRIT CARE. 2018;22(1):216.

2017

Uromodulin associates with cardiorenal function in patients with hypertension and cardiovascular disease
Algharably E, Bolbrinker J, Lezius S, Reibis R, Wegscheider K, Völler H, Kreutz R
J HYPERTENS. 2017;35(10):2053-2058.

Determination of ethyl glucuronide in human hair samples: A multivariate analysis of the impact of extraction conditions on quantitative results
Mueller A, Jungen H, Iwersen-Bergmann S, Raduenz L, Lezius S, Andresen-Streichert H
FORENSIC SCI INT. 2017;271:43-48.

Health-related quality of life after combined liver and kidney transplantation in children
Schmaeschke K, Lezius S, Grabhorn E, Kemper M, Brinkert F
PEDIATR TRANSPLANT. 2017;21(4):e12902.

Reliability and Correlation of Static and Dynamic Foot Arch Measurement in a Healthy Pediatric Population
Scholz T, Zech A, Wegscheider K, Lezius S, Braumann K, Sehner S, Hollander K
J AM PODIAT MED ASSN. 2017;107(5):419-427.

2016

Corrigendum to 'Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer", [Thromb. Res. 141 (2016) 39-48]
Claussen C, Rausch A, Lezius S, Amirkhosravi A, Davila M, Francis J, Hisada Y, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F
THROMB RES. 2016;146:135.

Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer
Claussen C, Rausch A, Lezius S, Amirkhosravi A, Davila M, Francis J, Hisada Y, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F
THROMB RES. 2016;141:39-48.

Maternal nutrition, inadequate gestational weight gain and birth weight: Results from a prospective birth cohort
Diemert A, Lezius S, Pagenkemper M, Hansen G, Drozdowska A, Hecher K, Arck P, Zyriax B
BMC PREGNANCY CHILDB. 2016;16:224.

Spleen size for the prediction of clinical outcome in patients with primary sclerosing cholangitis
Ehlken H, Wroblewski R, Corpechot C, Arrivé L, Lezius S, Hartl J, Denzer U, Lohse A, Chazouilleres O, Schramm C
GUT. 2016;65(7):1230-1232.

Validation of Transient Elastography and Comparison with Spleen Length Measurement for Staging of Fibrosis and Clinical Prognosis in Primary Sclerosing Cholangitis
Ehlken H, Wroblewski R, Corpechot C, Arrivé L, Rieger T, Hartl J, Lezius S, Hübener P, Schulze K, Zenouzi R, Sebode M, Peiseler M, Denzer U, Quaas A, Weiler-Normann C, Lohse A, Chazouilleres O, Schramm C
PLOS ONE. 2016;11(10):e0164224.

Volumetric Description of Brain Atrophy in Neuronal Ceroid Lipofuscinosis 2: Supratentorial Gray Matter Shows Uniform Disease Progression
Löbel U, Sedlacik J, Nickel M, Lezius S, Fiehler J, Nestrasil I, Kohlschütter A, Schulz A
AM J NEURORADIOL. 2016;37(10):1938 – 1943.

2015

A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy
Huber M, Lezius S, Reibis R, Treszl A, Kujawinska D, Jakob S, Wegscheider K, Völler H, Kreutz R
INT J MOL SCI. 2015;16(8):17456-17468.

Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success
Schreiber D, Rostock T, Fröhlich M, Sultan A, Servatius H, Hoffmann B, Lüker J, Berner I, Schäffer B, Wegscheider K, Lezius S, Willems S, Steven D
CIRC-ARRHYTHMIA ELEC. 2015;8(2):308-17.

Letzte Aktualisierung aus dem FIS: 20.11.2024 - 23:35 Uhr