From Ca2+ dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correction of aberrant Ca2+-handling
Brand T, Baumgarten B, Denzinger S, Reinders Y, Kleindl M, Schanbacher C, Funk F, Gedik N, Jabbasseh M, Kleinbongard P, Dudek J, Szendroedi J, Tolstik E, Schuh K, Krüger M, Dobrev D, Cuello F, Sickmann A, Schmitt J, Lorenz K
PHARMACOL RES. 2025;211:.

Intestinal Drug Absorption After Subarachnoid Hemorrhage and Elective Neurosurgery: Insights From Esomeprazole Pharmacokinetics
Kranawetter B, Brockmöller J, Sindern J, Hapke A, Bruns E, Harnisch L, Moerer O, Stenzig J, Mielke D, Rohde V, Abboud T
CRIT CARE MED. 2025;53(1):e140-e150.

Improving antiarrhythmic therapy for patients with atrial fibrillation using common genetic variants
Lemoine M, Fabritz L
HEART. 2025;111(4):145-146.

Metabolic Communication by SGLT2 Inhibition
Billing A, Kim Y, Gullaksen S, Schrage B, Raabe J, Hutzfeldt A, Demir F, Kovalenko E, Lassé M, Dugourd A, Fallegger R, Klampe B, Jaegers J, Li Q, Kravtsova O, Crespo-Masip M, Palermo A, Fenton R, Hoxha E, Blankenberg S, Kirchhof P, Huber T, Laugesen E, Zeller T, Chrysopolou M, Saez-Rodriguez J, Magnussen C, Eschenhagen T, Staruschenko A, Siuzdak G, Poulsen P, Schwab C, Cuello F, Vallon V, Rinschen M
CIRCULATION. 2024;149(11):860-884.

RNA Editing Holds Promise for Hypertrophic Cardiomyopathy Therapy
Carrier L
CIRCULATION. 2024;150(4):299-301.

Dapagliflozin and atrial fibrillation: elevated dosing to achieve class I antiarrhythmic effects?
Christ T, Schwedhelm E, Eschenhagen T
BASIC RES CARDIOL. 2024;119(3):505-507.

Imaging of Existing and Newly Translated Proteins Elucidates Mechanisms of Sarcomere Turnover
Douvdevany G, Erlich I, Haimovich-Caspi L, Mashiah T, Prondzynski M, Pricolo M, Alegre-Cebollada J, Linke W, Carrier L, Kehat I
CIRC RES. 2024;135(4):474-487.

Challenges and perspectives of heart repair with pluripotent stem cell-derived cardiomyocytes
Eschenhagen T, Weinberger F
NAT CARDIOVASC RES. 2024;3(5):515-524.

G protein coupled receptor transcripts in human immune cells and platelets
Hansen A, Martin D, Langer F, Harrison K, Kehrl J, Cicala C, Martinelli E, Brownstein M, Mezey E
SCI DATA. 2024;11(1):.

PDE8 Inhibition and Its Impact on ICa,L in Persistent Atrial Fibrillation: Evaluation of PDE8 as a Potential Drug Target
Ismaili D, Petersen J, Schulz C, Eschenhagen T, Koivumäki J, Christ T
J CARDIOVASC PHARM. 2024;84(6):606-612.

Generation of a patient-specific hiPS cell line with heterozygous GNB2 mutation (UKMi003-A) causative for human sinus node dysfunction and a corresponding CRISPR/Cas9-corrected isogenic control (UKMi004-A)
Kayser A, Dittmann S, Hamidi J, Laufer S, Krampe R, Mearini G, Hansen A, Schulze-Bahr E
STEM CELL RES. 2024;78:103446.

Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy
Meyer-Jens M, Wenzel K, Grube K, Rüdebusch J, Krämer E, Bahls M, Müller K, Voß H, Schlüter H, Felix S, Carrier L, Könemann S, Schlossarek S
Journal of molecular and cellular cardiology plus. 2024;7:100059.

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation
Pavlaki N, Froese A, Li W, De Jong K, Geertz B, Subramanian H, Mohagaonkar S, Luo X, Schubert M, Wiegmann R, Margaria J, Ghigo A, Kämmerer S, Hirsch E, El-Armouche A, Guan K, Nikolaev V
CARDIOVASC RES. 2024;120(9):1011-1023.

Chronic Activation of Tubulin Tyrosination Improves Heart Function
Pietsch N, Chen C, Kupsch S, Bacmeister L, Geertz B, Herrera-Rivero M, Siebels B, Voß H, Krämer E, Braren I, Westermann D, Schlüter H, Mearini G, Schlossarek S, van der Velden J, Caporizzo M, Lindner D, Prosser B, Carrier L
CIRC RES. 2024;135(9):910-932.

Physioxia rewires mitochondrial complex composition to protect stem cell viability
Raabe J, Wittig I, Laurette P, Stathopoulou K, Brand T, Schulze T, Klampe B, Orthey E, Carbrera-Orefice A, Meisterknecht J, Thiemann E, Laufer S, Domke-Shibamiya A, Reinsch M, Fuchs S, Kaiser J, Yang J, Zehr S, Wrona K, Lorenz K, Lukowski R, Hansen A, Gilsbach R, Brandes R, Ulmer B, Eschenhagen T, Cuello F
REDOX BIOL. 2024;77:103352.

PITX2 deficiency leads to atrial mitochondrial dysfunction
Reyat J, Sommerfeld L, O'Reilly M, Roth Cardoso V, Thiemann E, Khan A, O'Shea C, Harder S, Müller C, Barlow J, Stapley R, Chua W, Kabir S, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem S, Winters J, Zeemering S, Morgan N, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos G, Lorenz K, Cuello F, Kirchhof P, Fabritz L
CARDIOVASC RES. 2024;120(15):1907-1923.

Atrial hiPSC-CM as a Pharmacologic Model to Evaluate Anti-AF Drugs: Some Lessons From I Kur
Schulz C, Eschenhagen T, Christ T
J CARDIOVASC PHARM. 2024;84(5):479-485.

Human induced pluripotent stem cell-derived atrial cardiomyocytes recapitulate contribution of the slowly activating delayed rectifier currents IKs to repolarization in the human atrium
Sönmez M, Goldack S, Nurkkala E, Schulz C, Klampe B, Schulze T, Hansen A, Eschenhagen T, Koivumäki J, Christ T
EUROPACE. 2024;26(6):.

Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart
Stüdemann T, Schwarzová B, Schneidewind T, Geertz B, von Bibra C, Nehring M, Rössinger J, Wiegert J, Eschenhagen T, Weinberger F
STEM CELL REP. 2024;19(8):1053-1060.

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart
Waheed-Ullah Q, Wilsdon A, Abbad A, Rochette S, Bu'Lock F, Hitz M, Dombrowsky G, Cuello F, Brook J, Loughna S
J ANAT. 2024;245(1):70-83.

Jeanette Erdmann (1965–2023)
Aherrahrou R, Eschenhagen T, König I, Samani N, Schunkert H, Aherrahrou Z
NAT GENET. 2023;55(12):2016-2017.

Harnessing the power of RNA therapeutics in treating ischemic heart failure: the TRAIN-HEART story
Albert A, Balamurali D, Beslika E, Fernandez I, Genedy H, Babaei Khorzoughi R, Lauta F, Peppas P, Ragone I, Rizzari G, Sansonetti M, Silva J, Spanò G, Wrona K
FRONT CARDIOVASC MED. 2023;10:1228160.

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy
Algül S, Schuldt M, Manders E, Jansen V, Schlossarek S, de Goeij-de Haas R, Henneman A, Piersma S, Jimenez C, Michels M, Carrier L, Helmes M, van der Velden J, Kuster D
CIRC RES. 2023;133(5):387-399.

Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer S, Haas F, Wong M, Dumoulin B, Rischke P, Mühlig A, Sachs W, von Cossel K, Schulz K, Muschol N, Gersting S, Muntau A, Kretz O, Hahn O, Rinschen M, Mauer M, Bork T, Grahammer F, Liang W, Eierhoff T, Römer W, Hansen A, Meyer-Schwesinger C, Iaccarino G, Tøndel C, Marti H, Najafian B, Puelles V, Schell C, Huber T
J CLIN INVEST. 2023;133(11):.

Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution
Eschenhagen T
CIRC RES. 2023;132(6):741-743.

Kardiale Biomarker und ihre klinische Bedeutung
Eschenhagen T, Kirchhof P
DEUT MED WOCHENSCHR. 2023;148(10):605-609.

Arterielle Hypertonie
Eschenhagen T, Weil J
2023. Arzneiverordnungs-Report 2022. Ludwig P, Mühlbauer P, Seifert P (Hrsg.). 1. Aufl. Berlin, Heidelberg: Springer, 155 - 203.

Herzerkrankungen
Eschenhagen T, Weil J
2023. Arzneiverordnungs-Report 2022 . Ludwig P, Mühlbauer P, Seifert P (Hrsg.). 1. Aufl. Berlin, Heidelberg: Springer, 205 - 220.

Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes
Fischer M, Jakab M, Hirt M, Werner T, Engelhardt S, Sarikas A
FRONT PHYSIOL. 2023;14:1134339.

Mind the gap: leak currents and induced pluripotent stem cell-derived cardiomyocytes in translational cardiac electrophysiology
Heijman J, Christ T
EUROPACE. 2023;25(9):.

The DZHK research platform: Maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies
Hoffmann J, Hanß S, Kraus M, Schaller J, Schäfer C, Stahl D, Anker S, Anton G, Bahls T, Blankenberg S, Blumentritt A, Boldt L, Cordes S, Desch S, Doehner W, Dörr M, Edelmann F, Eitel I, Endres M, Engelhardt S, Erdmann J, Eulenburg K, Falk V, Felix S, Frank D, Franke T, Frey N, Friede T, Geidel L, Germans L, Grabmaier U, Halle M, Hausleiter J, Jakobi V, Jebran A, Jobs A, Kääb S, Karakas M, Katus H, Klatt A, Knosalla C, Krebser J, Landmesser U, Lee M, Lehnert K, Lesser S, Leyh K, Lorbeer R, Mach-Kolb S, Meder B, Nagel E, Nolte C, Parwani A, Petersmann A, Puls M, Rau H, Reiser M, Rienhoff O, Scharfe T, Schattschneider M, Scheel H, Schnabel R, Schuster A, Schmitt B, Seidler T, Seiffert M, Stähli B, Stas A, J Stocker T, von Stülpnagel L, Thiele H, Wachter R, Wakili R, Weis T, Weitmann K, Wichmann H, Wild P, Zeller T, Hoffmann W, Zeisberg E, Zimmermann W, Krefting D, Kühne T, Peters A, Hasenfuß G, Massberg S, Sommer T, Dimmeler S, Eschenhagen T, Nauck M
CLIN RES CARDIOL. 2023;112(7):923-941.

Proteomic Analysis in Valvular Cardiomyopathy: Aortic Regurgitation vs. Aortic Stenosis
Holst T, Petersen J, Ameling S, Müller L, Christ T, Gedeon N, Eschenhagen T, Reichenspurner H, Hammer E, Girdauskas E
CELLS-BASEL. 2023;12(6):.

Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective
Ismaili D, Schulz C, Horváth A, Koivumäki J, Mika D, Hansen A, Eschenhagen T, Christ T
FRONT PHYSIOL. 2023;14:1132165.

The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes
Kayser A, Dittmann S, Šarić T, Mearini G, Verkerk A, Schulze-Bahr E
INT J MOL SCI. 2023;24(20):15290.

An arrhythmogenic metabolite in atrial fibrillation
Krause J, Nickel A, Madsen A, Aitken-Buck H, Stoter A, Schrapers J, Ojeda F, Geiger K, Kern M, Kohlhaas M, Bertero E, Hofmockel P, Hübner F, Assum I, Heinig M, Müller C, Hansen A, Krause T, Park D, Just S, Aïssi D, Börnigen D, Lindner D, Friedrich N, Alhussini K, Bening C, Schnabel R, Karakas M, Iacoviello L, Salomaa V, Linneberg A, Tunstall-Pedoe H, Kuulasmaa K, Kirchhof P, Blankenberg S, Christ T, Eschenhagen T, Lamberts R, Maack C, Stenzig J, Zeller T
J TRANSL MED. 2023;21(1):566.

Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism
Loos M, Klampe B, Schulze T, Yin X, Theofilatos K, Ulmer B, Schulz C, Behrens C, van Bergen T, Adami E, Maatz H, Schweizer M, Brodesser S, Skryabin B, Rozhdestvensky T, Bodbin S, Stathopoulou K, Christ T, Denning C, Hübner N, Mayr M, Cuello F, Eschenhagen T, Hansen A
STEM CELL REP. 2023;18(11):2123-2137.

Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle
Münkler P, Klatt N, Scherschel K, Kuklik P, Jungen C, Cavus E, Eickholt C, Christoph J, Lemoine M, Christ T, Willems S, Riedel R, Kirchhof P, Meyer C
EUROPACE. 2023;25(2):688–697.

Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: a two-hit model of hypertrophic cardiomyopathy
Nollet E, Algül S, Goebel M, Schlossarek S, van der Wel N, Jans J, van de Wiel M, Knol J, Pham T, Piersma S, de Goeij-de Haas R, Hermans J, van Klinken J, van Weeghel M, Houtkooper R, Carrier L, Jimenez C, Kuster D, van der Velden J
Journal of molecular and cellular cardiology plus. 2023;6:100050.

Organ-specific model of simulated ischemia/reperfusion and hyperglycemia based on engineered heart tissue
Pálóczi J, Paál Á, Pigler J, Kiss B, Rhoden A, Varga Z, Ferdinandy P, Eschenhagen T, Görbe A
VASC PHARMACOL. 2023;152:107208.

Resting membrane potential is less negative in trabeculae from right atrial appendages of women, but action potential duration does not shorten with age
Pecha S, Ismaili D, Geelhoed B, Knaut M, Reichenspurner H, Eschenhagen T, Schnabel R, Christ T, Ravens U
J MOL CELL CARDIOL. 2023;176:1-10.

Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis
Petersen J, Iqbal S, Gedeon N, Kloth B, Pecha S, Yildirim Y, Eschenhagen T, Reichenspurner H, Christ T, Girdauskas E
J CLIN MED. 2023;12(8):.

Generation of a homozygous CRYAB p.Arg120Gly mutant (UKEi001-A-1) from a human iPSC line
Pietsch N, Cheng J, Fazio A, Ewald L, Alizoti E, Krämer E, Orthey E, Carrier L, Singh S
STEM CELL RES. 2023;71:103188.

The detyrosination/re-tyrosination cycle of tubulin and its role and dysfunction in neurons and cardiomyocytes
Sanyal C, Pietsch N, Ramirez Rios S, Peris L, Carrier L, Moutin M
SEMIN CELL DEV BIOL. 2023;137:46-62.

PITX2 Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation
Schulz C, Lemoine M, Mearini G, Koivumäki J, Sani J, Schwedhelm E, Kirchhof P, Ghalawinji A, Stoll M, Hansen A, Eschenhagen T, Christ T
CIRC-ARRHYTHMIA ELEC. 2023;16(3):e011602.

A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM
Schulz C, Sönmez M, Krause J, Schwedhelm E, Bangfen P, Alihodzic D, Hansen A, Eschenhagen T, Christ T
STEM CELL REP. 2023;18(11):2096-2107.

Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES
Schwarzová B, Stüdemann T, Sönmez M, Rössinger J, Pan B, Eschenhagen T, Stenzig J, Wiegert J, Christ T, Weinberger F
PFLUG ARCH EUR J PHY. 2023;475(12):1463-1477.

Immature human engineered heart tissues engraft in a guinea pig chronic injury model
von Bibra C, Shibamiya A, Bähr A, Geertz B, Köhne M, Stuedemann T, Starbatty J, Horneffer-van der Sluis V, Klostermeier U, Hornaschewitz N, Li X, Wolf E, Klymiuk N, Krane M, Kupatt C, Hiebl B, Eschenhagen T, Weinberger F
DIS MODEL MECH. 2023;16(5):.

Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics
Arbustini E, Behr E, Carrier L, van Duijn C, Evans P, Favalli V, van der Harst P, Haugaa K, Jondeau G, Kääb S, Kaski J, Kavousi M, Loeys B, Pantazis A, Pinto Y, Schunkert H, Di Toro A, Thum T, Urtis M, Waltenberger J, Elliott P
EUR HEART J. 2022;43(20):1901-1916.

Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice
Bhandare A, van de Wiel J, Roberts R, Braren I, Huckstepp R, Dale N
ELIFE. 2022;11:.

Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)
de Boer R, Heymans S, Backs J, Carrier L, Coats A, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot J, Knöll R, Kupatt C, Linke W, Seidman C, Tocchetti C, van der Velden J, Walsh R, Seferovic P, Thum T
EUR J HEART FAIL. 2022;24(3):406-420.

Activation of an accessory pathway of glucose metabolism to treat dilated cardiomyopathy
Eschenhagen T
EUR HEART J. 2022;43(36):3490-3492.

How to repair a broken heart with pluripotent stem cell-derived cardiomyocytes
Eschenhagen T, Ridders K, Weinberger F
J MOL CELL CARDIOL. 2022;163:106-117.

G Protein-Coupled Receptor 15 Expression Is Associated with Myocardial Infarction
Haase T, Müller C, Stoffers B, Kirn P, Waldenberger M, Kaiser F, Karakas M, Kim S, Voss S, Wild P, Lackner K, Andersson J, Söderberg S, Lindner D, Zeller T
INT J MOL SCI. 2022;24(1):.

Erratum. Performance of the ESC 0/1-h and 0/3-h Algorithm for the Rapid Identification of Myocardial Infarction Without ST-Elevation in Patients With Diabetes. Diabetes Care 2020;43:460-467
Haller P, Boeddinghaus J, Neumann J, Sörensen N, Hartikainen T, Goßling A, Nestelberger T, Twerenbold R, Lehmacher J, Keller T, Zeller T, Blankenberg S, Mueller C, Westermann D
DIABETES CARE. 2022;45(7):1701-1702.

Regulation of APD and Force by the Na+/Ca2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue
Ismaili D, Gurr K, Horváth A, Yuan L, Lemoine M, Schulz C, Sani J, Petersen J, Reichenspurner H, Kirchhof P, Jespersen T, Eschenhagen T, Hansen A, Koivumäki J, Christ T
CELLS-BASEL. 2022;11(15):.

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I
Kamynina A, Guttzeit S, Eaton P, Cuello F
HYPERTENSION. 2022;79(5):946-956.

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes
Kloth B, Mearini G, Weinberger F, Stenzig J, Geertz B, Starbatty J, Lindner D, Schumacher U, Reichenspurner H, Eschenhagen T, Hirt M
SCI REP-UK. 2022;12(1):.

A potential future Fontan modification: preliminary in vitro data of a pressure-generating tube from engineered heart tissue
Köhne M, Behrens C, Stüdemann T, Bibra C, Querdel E, Shibamiya A, Geertz B, Olfe J, Hüners I, Jockenhövel S, Hübler M, Eschenhagen T, Sachweh J, Weinberger F, Biermann D
EUR J CARDIO-THORAC. 2022;62(2):.

Human-Engineered Atrial Tissue for Studying Atrial Fibrillation
Krause J, Lemme M, Mannhardt I, Eder A, Ulmer B, Eschenhagen T, Stenzig J
2022. Cardiac Tissue Engineering. Coulombe K, Black III L (Hrsg.). 1. Aufl. New York, NY: Humana Press, 159-173.

RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes
Levay M, Krobert K, Vogt A, Ahmad A, Jungmann A, Neuber C, Pasch S, Hansen A, Müller O, Lutz S, Wieland T
BASIC RES CARDIOL. 2022;117(1):.

Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors
Mann A, Schäfer W, Adriouch S, Börner K, Grimm D, Braren I, Koch-Nolte F
2022. The P2X7 Receptor. Nicke A (Hrsg.). 1. Aufl. New York, NY: HUMANA PRESS INC, 129-144.

A biallelic loss-of-function variant in MYZAP is associated with a recessive form of severe dilated cardiomyopathy
Maver A, Zigman T, Rangrez A, Coric M, Homolak J, Saric D, Skific I, Udovicic M, Zekusic M, Saleem U, Laufer S, Hansen A, Frey N, Baric I, Peterlin B
CSH MOL CASE STUD. 2022;8(5):.

Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh
Petersen J, Castro L, Bengaard A, Pecha S, Ismaili D, Schulz C, Sahni J, Steenpass A, Meier C, Reichenspurner H, Jespersen T, Eschenhagen T, Christ T
J CARDIOVASC PHARM. 2022;79(5):678-686.

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy - Addendum
Prondzynski M, Lemoine M, Zech A, Horváth A, Di Mauro V, Koivumäki J, Kresin N, Busch J, Krause T, Krämer E, Schlossarek S, Spohn M, Friedrich F, Münch J, Laufer S, Redwood C, Volk A, Hansen A, Mearini G, Catalucci D, Meyer C, Christ T, Patten M, Eschenhagen T, Carrier L
EMBO MOL MED. 2022;14(8):.

Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues
Reed E, Fellows A, Lu R, Rienks M, Schmidt L, Yin X, Duregotti E, Brandt M, Krasemann S, Hartmann K, Barallobre-Barreiro J, Addison O, Cuello F, Hansen A, Mayr M
Matrix biology plus. 2022;16:.

Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations
Rhoden A, Schulze T, Pietsch N, Christ T, Hansen A, Eschenhagen T
AM J PHYSIOL-HEART C. 2022;322(3):H373-H385.

An Improved Model of Moderate Sleep Apnoea for Investigating Its Effect as a Comorbidity on Neurodegenerative Disease
Roberts R, Wall M, Braren I, Dhillon K, Evans A, Dunne J, Nyakupinda S, Huckstepp R
FRONT AGING NEUROSCI. 2022;14:.

Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway
Sonmez M, Shahzadi A, Kose C, Sonmez H, Ozyazgan S, Akkan A
FRONT PHARMACOL. 2022;13:.

CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes
Stathopoulou K, Schnittger J, Raabe J, Fleischer F, Mangels N, Piasecki A, Findlay J, Hartmann K, Krasemann S, Schlossarek S, Uebeler J, Wixler V, Blake D, Baillie G, Carrier L, Ehler E, Cuello F
FEBS J. 2022;289(15):4622-4645.

Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue
Stenzig J, Lemoine M, Stoter A, Wrona K, Lemme M, Mulla W, Etzion Y, Eschenhagen T, Hirt M
J MOL CELL CARDIOL. 2022;163:97-105.

Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury
Stüdemann T, Rössinger J, Manthey C, Geertz B, Srikantharajah R, von Bibra C, Shibamiya A, Köhne M, Wiehler A, Wiegert J, Eschenhagen T, Weinberger F
CIRCULATION. 2022;146(15):1159-1169.

The guinea pig model in cardiac regeneration research. Current tissue engineering approaches and future directions
Stüdemann T, Weinberger F
2022. Advanced Technologies in Cardiovascular Bioengineering. Zhang J, Serpooshan V (Hrsg.). 1. Aufl. Springer International Publishing, 103-122.

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
van der Velden J, Asselbergs F, Bakkers J, Batkai S, Bertrand L, Bezzina C, Bot I, Brundel B, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson S, Dendorfer A, Duncker D, Eschenhagen T, Fabritz L, Falcão-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepeköylü C, Gyongyosi M, Guzik T, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra A, Hulot J, Kuster D, van Laake L, Lecour S, Leiner T, Linke W, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme C, Rosenhahn B, Schotten U, Schulz R, Sipido K, Sluijter J, van Steenbeek F, Steffens S, Terracciano C, Tocchetti C, Vlasman P, Yeung K, Zacchigna S, Zwaagman D, Thum T
CARDIOVASC RES. 2022;118(15):3016-3051.

Human engineered heart tissue transplantation in a guinea pig chronic injury model
von Bibra C, Shibamiya A, Geertz B, Querdel E, Köhne M, Stüdemann T, Starbatty J, Schmidt F, Hansen A, Hiebl B, Eschenhagen T, Weinberger F
J MOL CELL CARDIOL. 2022;166:1-10.

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes
Wickramasinghe N, Sachs D, Shewale B, Gonzalez D, Dhanan-Krishnan P, Torre D, LaMarca E, Raimo S, Dariolli R, Serasinghe M, Mayourian J, Sebra R, Beaumont K, Iyengar S, French D, Hansen A, Eschenhagen T, Chipuk J, Sobie E, Jacobs A, Akbarian S, Ischiropoulos H, Ma'ayan A, Houten S, Costa K, Dubois N
CELL STEM CELL. 2022;29(4):559-576.e7.

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes
Zech A, Prondzynski M, Singh S, Pietsch N, Orthey E, Alizoti E, Busch J, Madsen A, Behrens C, Meyer-Jens M, Mearini G, Lemoine M, Krämer E, Mosqueira D, Virdi S, Indenbirken D, Depke M, Salazar M, Völker U, Braren I, Pu W, Eschenhagen T, Hammer E, Schlossarek S, Carrier L
CELLS-BASEL. 2022;11(17):.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

AUTOPHAGY. 2021.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

AUTOPHAGY. 2021;17(1):1-382.

DNA Methylation in Heart Failure
Anene-Nzelu C, Stenzig J, Foo R
2021. Epigenetics in Cardiovascular Disease. Devaux Y, Robinson E (Hrsg.). 1. Aufl. Elsevier Inc., 55-76.

Characterization of the PLN p.Arg14del Mutation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Badone B, Ronchi C, Lodola F, Knaust A, Hansen A, Eschenhagen T, Zaza A
INT J MOL SCI. 2021;22(24):.

Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling
Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin W, Ermolaeva E, Martínez-López D, Lindberg E, Duregotti E, Daróczi L, Hasman M, Schmidt L, Singh B, Lu R, Baig F, Siedlar A, Cuello F, Catibog N, Theofilatos K, Shah A, Crespo-Leiro M, Doménech N, Hübner N, Merkely B, Mayr M
CIRCULATION. 2021;144(25):2021-2034.

A proteomics-based assessment of inflammation signatures in endotoxemia
Burnap S, Mayr U, Shankar-Hari M, Cuello F, Thomas M, Shah A, Sabroe I, Storey R, Mayr M
MOL CELL PROTEOMICS. 2021;20:100021.

Targeting the population for gene therapy with MYBPC3
Carrier L
J MOL CELL CARDIOL. 2021;150:101-108.

Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?
Christ T, Lemoine M, Eschenhagen T
NAT COMMUN. 2021;12(1):1725.

Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease
Cremer S, Pilgram L, Berkowitsch A, Stecher M, Rieg S, Shumliakivska M, Bojkova D, Wagner J, Aslan G, Spinner C, Luxán G, Hanses F, Dolff S, Piepel C, Ruppert C, Guenther A, Rüthrich M, Vehreschild J, Wille K, Haselberger M, Heuzeroth H, Hansen A, Eschenhagen T, Cinatl J, Ciesek S, Dimmeler S, Borgmann S, Zeiher A
PLOS ONE. 2021;16(10):.

Regulation of Cardiac PKA Signaling by cAMP and Oxidants
Cuello F, Herberg F, Stathopoulou K, Henning P, Diering S
ANTIOXIDANTS-BASEL. 2021;10(5):663.

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation
Cuello F, Knaust A, Saleem U, Loos M, Raabe J, Mosqueira D, Laufer S, Schweizer M, van der Kraak P, Flenner F, Ulmer B, Braren I, Yin X, Theofilatos K, Ruiz-Orera J, Patone G, Klampe B, Schulze T, Piasecki A, Pinto Y, Vink A, Hübner N, Harding S, Mayr M, Denning C, Eschenhagen T, Hansen A
EMBO MOL MED. 2021;13(6):e13074.

Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation
Dolce B, Christ T, Grammatika Pavlidou N, Yildirim Y, Reichenspurner H, Eschenhagen T, Nikolaev V, Kaumann A, Molina C
N-S ARCH PHARMACOL. 2021;394(2):291-298.

Ouabain worsens diastolic sarcomere length in myocytes from a cardiomyopathy mouse model
Düsener S, Flenner F, Maack C, Kohlhaas M, Bay J, Carrier L, Friedrich F
EUR J PHARMACOL. 2021;904:.

Translational investigation of electrophysiology in hypertrophic cardiomyopathy
Flenner F, Jungen C, Küpker N, Ibel A, Kruse M, Koivumäki J, Rinas A, Zech A, Rhoden A, Wijnker P, Lemoine M, Steenpass A, Girdauskas E, Eschenhagen T, Meyer C, van der Velden J, Patten-Hamel M, Christ T, Carrier L
J MOL CELL CARDIOL. 2021;157:77-89.

Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Gilbert G, Kadur Nagaraju C, Duelen R, Amoni M, Bobin P, Eschenhagen T, Roderick H, Sampaolesi M, Sipido K
FRONT CELL DEV BIOL. 2021;9:.

Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia
Hannemann J, Cordts K, Seniuk A, Choe C, Schmidt-Hutten L, Duque Escobar J, Weinberger F, Böger R, Schwedhelm E
FRONT PHYSIOL. 2021;12:703069.

Bluthochdruck - Herz und Gefäße schützen: Medikamente - Die richtige Wahl treffen
Hirt M, Stenzig J, Eschenhagen T
2021.

Regulation of basal and norepinephrine-induced cAMP and ICa in hiPSC-cardiomyocytes: Effects of culture conditions and comparison to adult human atrial cardiomyocytes
Iqbal Z, Ismaili D, Dolce B, Petersen J, Reichenspurner H, Hansen A, Kirchhof P, Eschenhagen T, Nikolaev V, Molina C, Christ T
CELL SIGNAL. 2021;82:109970.

In vivo grafting of large engineered heart tissue patches for cardiac repair
Jabbour R, Owen T, Pandey P, Reinsch M, Wang B, King O, Couch L, Pantou D, Pitcher D, Chowdhury R, Pitoulis F, Handa B, Kit-Anan W, Perbellini F, Myles R, Stuckey D, Dunne M, Shanmuganathan M, Peters N, Ng F, Weinberger F, Terracciano C, Smith G, Eschenhagen T, Harding S
JCI INSIGHT. 2021;6(15):.

New Strategies for the Treatment of Atrial Fibrillation
Jost N, Christ T, Magyar J
PHARMACEUTICALS-BASE. 2021;14(9):.

FYCO1 regulates cardiomyocyte autophagy and prevents heart failure due to pressure overload in vivo
Kuhn C, Menke M, Senger F, Mack C, Dierck F, Hille S, Schmidt I, Brunke G, Bünger P, Schmiedel N, Will R, Sossalla S, Frank D, Eschenhagen T, Carrier L, Lüllmann-Rauch R, Yusuf A, Frey N
JACC-BASIC TRANSL SC. 2021;6(4):365-380.

Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy
Ku M, Kober F, Lai Y, Pohlmann A, Qadri F, Bader M, Carrier L, Niendorf T
J CARDIOVASC MAGN R. 2021;23(1):63.

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: The New Working Horse in Cardiovascular Pharmacology?
Lemoine M, Christ T
J CARDIOVASC PHARM. 2021;77(3):265-266.

Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes
Madsen A, Krause J, Höppner G, Hirt M, Tan W, Lim I, Hansen A, Nikolaev V, Foo R, Eschenhagen T, Stenzig J
J MOL CELL CARDIOL. 2021;154:115-123.

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains
Pavlaki N, De Jong K, Geertz B, Nikolaev V, Froese A
CELLS-BASEL. 2021;10(3):.

No impact of sex and age on beta-adrenoceptor-mediated inotropy in human right atrial trabeculae
Pecha S, Geelhoed B, Kempe R, Berk E, Engel A, Girdauskas E, Reichenspurner H, Ravens U, Kaumann A, Eschenhagen T, Schnabel R, Christ T
ACTA PHYSIOL. 2021;231(3):.

Blunted beta-adrenoceptor-mediated inotropy in valvular cardiomyopathy: another piece of the puzzle in human aortic valve disease
Petersen J, Kloth B, Iqbal S, Reichenspurner H, Geelhoed B, Schnabel R, Eschenhagen T, Christ T, Girdauskas E
EUR J CARDIO-THORAC. 2021;60(1):56-63.

Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner
Querdel E, Reinsch M, Castro L, Köse D, Bähr A, Reich S, Geertz B, Ulmer B, Schulze M, Lemoine M, Krause T, Lemme M, Sani J, Shibamiya A, Stüdemann T, Köhne M, Bibra C, Hornaschewitz N, Pecha S, Nejahsie Y, Mannhardt I, Christ T, Reichenspurner H, Hansen A, Klymiuk N, Krane M, Kupatt C, Eschenhagen T, Weinberger F
CIRCULATION. 2021;143(20):1991-2006.

Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue
Radke M, Badillo-Lisakowski V, Britto-Borges T, Kubli D, Jüttner R, Parakkat P, Carballo J, Hüttemeister J, Liss M, Hansen A, Dieterich C, Mullick A, Gotthardt M
SCI TRANSL MED. 2021;13(622):.

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue
Rhoden A, Friedrich F, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer B, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F
REDOX BIOL. 2021;41:101951.

Cas9-expressing chickens and pigs as resources for genome editing in livestock
Rieblinger B, Sid H, Bozoglu T, Klinger R, Schlickenrieder A, Lengyel K, Flisikowski K, Flisikowska T, Simm N, Grodziecki A, Perleberg C, Bähr A, Carrier L, Wolf E, Kessler B, Kettler L, Luksch H, Hagag I, Wise D, Kaufman J, Kaufer B, Kupatt C, Schnieke A, Schusser B
P NATL ACAD SCI USA. 2021;118(10):.

Proteomic and functional studies reveal detyrosinated tubulin as treatment target in sarcomere mutation-induced hypertrophic cardiomyopathy
Schuldt M, Pei J, Harakalova M, Dorsch L, Schlossarek S, Mokry M, Knol J, Pham T, Schelfhorst T, Piersma S, Dos Remedios C, Dalinghaus M, Michels M, Asselbergs F, Moutin M, Carrier L, Jimenez C, van der Velden J, Kuster D
CIRC-HEART FAIL. 2021;14(1):e007022.

Generation and characterization of human engineered heart tissue with a pharmacological off-on switch
Stüdemann T, Manthey C, Schulz C, Köhne M, Domke-Shibamiya A, Penalosa Ruiz G, Christ T, Eschenhagen T, Weinberger F
2021. EMBO Workshop: Cardiomyocyte Biology. .

Generation of human engineered heart tissue with light activated ion channels
Stüdemann T, Pan B, Köhne M, Bibra C, Domke-Shibamiya A, Stenzig J, Eschenhagen T, Weinberger F
2021. Early Career Investigators pre-meeting Symposium at International Society for Heart Research- European Section. .

Contractile force of transplanted cardiomyocytes contributes to heart function after injury
Stüdemann T, Rössinger J, Manthey C, Geertz B, Srikantharajah R, Bibra C, Shibamiya A, Köhne M, Wiehler A, Wiegert J, Eschenhagen T, Weinberger F
2021.

A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy
Thottakara T, Lund N, Krämer E, Kirchhof P, Carrier L, Patten M
BIOMOLECULES. 2021;11(11):.

Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy
Warnecke N, Ulmer B, Laufer S, Shibamiya A, Krämer E, Neuber C, Hanke S, Behrens C, Loos M, Münch J, Kühnisch J, Klaassen S, Eschenhagen T, Patten-Hamel M, Carrier L, Mearini G
STEM CELL RES. 2021;55:102489.

Cardiac Regeneration: New Hope for an Old Dream
Weinberger F, Eschenhagen T
ANNU REV PHYSIOL. 2021;83:59-81.

A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway
Wenzel K, Krämer E, Geertz B, Carrier L, Felix S, Könemann S, Schlossarek S
FRONT PHYSIOL. 2021;12:614878.

Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Zacchigna S, Paldino A, Falcão-Pires I, Daskalopoulos E, Dal Ferro M, Vodret S, Lesizza P, Cannatà A, Miranda-Silva D, Lourenço A, Pinamonti B, Sinagra G, Weinberger F, Eschenhagen T, Carrier L, Kehat I, Russo M, Tocchetti C, Ghigo A, Hirsch E, Dawson D, Ciccarelli M, Oliveti M, Linke W, Cuijpers I, Heymans S, Hamdani N, de Boer M, Duncker D, Kuster D, van der Velden J, Beauloye C, Bertrand L, Mayr M, Giacca M, Leuschner F, Backs J, Thum T
CARDIOVASC RES. 2021;117(1):43-59.

Magnetic Adjustment of Afterload in Engineered Heart Tissues
Becker B, Rodriguez M, Werner T, Stenzig J, Eschenhagen T, Hirt M
JOVE-J VIS EXP. 2020;(159):.

Medikamentöse Kontrolle kardiovaskulärer Risikofaktoren bei HIV-Patienten unter ART Therapie
Bergmann M, Eschenhagen T
KARDIOLOGE. 2020;14(1):35-37.

Gene therapy for inherited arrhythmias
Bezzerides V, Prondzynski M, Carrier L, Pu W
CARDIOVASC RES. 2020;116(9):1635-1650.

Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics
Bhagwan J, Mosqueira D, Chairez-Cantu K, Mannhardt I, Bodbin S, Bakar M, Smith J, Denning C
J MOL CELL CARDIOL. 2020;2020(145):43-53.

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Bojkova D, Wagner J, Shumliakivska M, Aslan G, Saleem U, Hansen A, Luxán G, Günther S, Pham M, Krishnan J, Harter P, Ermel U, Frangakis A, Milting H, Zeiher A, Klingel K, Cinatl J, Dendorfer A, Eschenhagen T, Tschöpe C, Ciesek S, Dimmeler S
CARDIOVASC RES. 2020;116(14):2207-2215.

Depletion of Vasohibin 1 Speeds Contraction and Relaxation in Failing Human Cardiomyocytes
Chen C, Salomon A, Caporizzo M, Curry S, Kelly N, Bedi K, Bogush A, Krämer E, Schlossarek S, Janiak P, Moutin M, Carrier L, Margulies K, Prosser B
CIRC RES. 2020;127(2):e14-e27.

Cardiac cGMP Signaling in Health and Disease: Location, Location, Location
Cuello F, Nikolaev V
J CARDIOVASC PHARM. 2020;75(5):399-409.

Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
de Boer R, Hulot J, Tocchetti C, Aboumsallem J, Ameri P, Anker S, Bauersachs J, Bertero E, Coats A, Čelutkienė J, Chioncel O, Dodion P, Eschenhagen T, Farmakis D, Bayes-Genis A, Jäger D, Jankowska E, Kitsis R, Konety S, Larkin J, Lehmann L, Lenihan D, Maack C, Moslehi J, Müller O, Nowak-Sliwinska P, Piepoli M, Ponikowski P, Pudil R, Rainer P, Ruschitzka F, Sawyer D, Seferovic P, Suter T, Thum T, van der Meer P, Van Laake L, von Haehling S, Heymans S, Lyon A, Backs J
EUR J HEART FAIL. 2020;22(12):2272-2289.

Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?
de Korte T, Katili P, Mohd Yusof N, van Meer B, Saleem U, Burton F, Smith G, Clements P, Mummery C, Eschenhagen T, Hansen A, Denning C
ANNU REV PHARMACOL. 2020;60:529-551.

M/M/Infinity Birth-Death Processes - A Quantitative Representational Framework to Summarize and Explain Phase Singularity and Wavelet Dynamics in Atrial Fibrillation
Dharmaprani D, Jenkins E, Aguilar M, Quah J, Lahiri A, Tiver K, Mitchell L, Kuklik P, Meyer C, Willems S, Clayton R, Nash M, Nattel S, McGavigan A, Ganesan A
FRONT PHYSIOL. 2020;11:.

Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents
Diering S, Stathopoulou K, Goetz M, Rathjens L, Harder S, Piasecki A, Raabe J, Schulz S, Brandt M, Pflaumenbaum J, Fuchs U, Donzelli S, Sadayappan S, Nikolaev V, Flenner F, Ehler E, Cuello F
J BIOL CHEM. 2020;295(45):15342-15365.

Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
Feyen D, McKeithan W, Bruyneel A, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen R, Ginsburg K, Lam C, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya P, Behrens C, Ranjbarvaziri S, Maas R, Greenhaw M, Bernstein D, Wu J, Bers D, Eschenhagen T, Metallo C, Mercola M
CELL REP. 2020;32(3):107925.

Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study
Funcke S, Werner T, Hein M, Ulmer B, Hansen A, Eschenhagen T, Hirt M
BIOMOLECULES. 2020;10(9):.

Case Report on Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca)
Horváth A, Christ T, Koivumäki J, Prondzynski M, Zech A, Spohn M, Saleem U, Mannhardt I, Ulmer B, Girdauskas E, Meyer C, Hansen A, Eschenhagen T, Lemoine M
CELLS-BASEL. 2020;9(1):.

Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?
Ismaili D, Geelhoed B, Christ T
PROG BIOPHYS MOL BIO. 2020;157:33-39.

Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue
Lemme M, Braren I, Prondzynski M, Aksehirlioglu B, Ulmer B, Schulze M, Ismaili D, Meyer C, Hansen A, Christ T, Lemoine M, Eschenhagen T
CARDIOVASC RES. 2020;116(8):1487-1499.

Intermittent optogenetic tachypacing of atrial engineered heart tissue induces only limited electrical remodelling
Lemoine M, Lemme M, Ulmer B, Braren I, Krasemann S, Hansen A, Kirchhof P, Meyer C, Eschenhagen T, Christ T
J CARDIOVASC PHARM. 2020;77(3):291-299.

An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility
Madsen A, Höppner G, Krause J, Hirt M, Laufer S, Schweizer M, Tan W, Mosqueira D, Anene-Nzelu C, Lim I, Foo R, Eschenhagen T, Stenzig J
CIRCULATION. 2020;142(16):1562-1578.

Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format
Mannhardt I, Saleem U, Mosqueira D, Loos M, Ulmer B, Lemoine M, Larsson C, Améen C, de Korte T, Vlaming M, Harris K, Clements P, Denning C, Hansen A, Eschenhagen T
STEM CELL REP. 2020;15(4):983-998.

Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis
Mollenhauer M, Mehrkens D, Klinke A, Lange M, Friedrich K, Braumann S, Geißen S, Simskyilmaz S, Nettersheim F, Lee S, Peinkofer G, Geisler A, Geis B, Schwoerer A, Carrier L, Freeman B, Dewenter M, Luo X, El-Armouche A, Wagner M, Adam M, Baldus S, Rudolph V
SCI REP-UK. 2020;10(1):.

Regulation of ICa,L and force by PDEs in human-induced pluripotent stem cell-derived cardiomyocytes
Saleem U, Ismaili D, Mannhardt I, Pinnschmidt H, Schulze T, Christ T, Eschenhagen T, Hansen A
BRIT J PHARMACOL. 2020;177(13):3036-3045.

Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency
Saleem U, Mannhardt I, Braren I, Denning C, Eschenhagen T, Hansen A
STEM CELL REP. 2020;14(2):312-324.

Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes
Saleem U, van Meer B, Katili P, Mohd Yusof N, Mannhardt I, Garcia A, Tertoolen L, de Korte T, Vlaming M, McGlynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, Burton F, Smith G, Clements P, Mummery C, Eschenhagen T, Hansen A, Denning C
TOXICOL SCI. 2020;176(1):103-123.

Cell Banking of hiPSCs: A Practical Guide to Cryopreservation and Quality Control in Basic Research
Shibamiya A, Schulze E, Krauß D, Augustin C, Reinsch M, Schulze M, Steuck S, Mearini G, Mannhardt I, Schulze T, Klampe B, Werner T, Saleem U, Knaust A, Laufer S, Neuber C, Lemme M, Behrens C, Loos M, Weinberger F, Fuchs S, Eschenhagen T, Hansen A, Ulmer B
Current protocols in stem cell biology. 2020;55(1):e127.

Is Desmin Propensity to Aggregate Part of its Protective Function?
Singh S, Kadioglu H, Patel K, Carrier L, Agnetti G
CELLS-BASEL. 2020;9(2):491.

A high throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway
Singh S, Meyer-Jens M, Alizoti E, Bacon W, Davis G, Osinska H, Gulick J, Reischmann-Düsener S, Orthey E, McLendon P, Molkentin J, Schlossarek S, Robbins J, Carrier L
AUTOPHAGY. 2020.

Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation
Soattin L, Lubberding A, Bentzen B, Christ T, Jespersen T
FRONT PHYSIOL. 2020;11:493.

Assessment of Cardiotoxicity With Stem Cell-based Strategies
Stoter A, Hirt M, Stenzig J, Weinberger F
CLIN THER. 2020;42(10):1892-1910.

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects
Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert M, Godoy P, Schmidt-Heck W, Nordbeck P, Ludwig J, Homann S, Wiegering A, Shaykhutdinov T, Kratz C, Knüchel R, Müller-Hermelink H, Rosenwald A, Frey N, Eichler J, Dobrev D, El-Armouche A, Hengstler J, Müller O, Hinrichs K, Cuello F, Zernecke A, Lorenz K
NAT COMMUN. 2020;11(1):1733.

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
Trembinski D, Bink D, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo C, Costa I, Schürmann C, Leisegang M, Brandes R, Alekseeva T, Brill B, Wietelmann A, Johnson C, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt M, Yorgan K, Eschenhagen T, Kirchhof L, Hofmann P, Jaé N, Wittig I, Hamdani N, Bischof C, Krishnan J, Houtkooper R, Dimmeler S, Boon R
NAT COMMUN. 2020;11(1):2039.

Association of Previous Myocardial Infarction and Time to Presentation With Suspected Acute Myocardial Infarction
Troester V, Strebel I, Nestelberger T, Boeddinghaus J, Rubini G, Lopez-Ayala P, Koechlin L, Glarner N, Prepoudis A, Miró Ò, APACE I
J AM HEART ASSOC. 2020;10(1):.

Human pluripotent stem cell-derived cardiomyocytes for studying energy metabolism
Ulmer B, Eschenhagen T
BBA-MOL CELL RES. 2020;1867(3):118471.

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy
Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger J, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer A, Schmitz J, Bräsen J, Schmitto J, Gyöngyösi M, Löser A, Hirt M, Eschenhagen T, Engelhardt S, Bär C, Thum T
EUR HEART J. 2020;41(36):3462-3474.

An epidemiological study exploring a possible impact of treatment with ACE inhibitors or angiotensin receptor blockers on ACE2 plasma concentrations
Wild P, Dimmeler S, Eschenhagen T
J MOL CELL CARDIOL. 2020;141:108-109.

The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
Xie W, Miehe M, Laufer S, Johnsen S
CELL DEATH DIS. 2020;11(4):287.

Autophagy in cardiomyopathies
Zech A, Singh S, Schlossarek S, Carrier L
BBA-MOL CELL RES. 2020;1867(3):118432.

Diagnosis of acute myocardial infarction in the presence of left bundle branch block

HEART. 2019;105(20):1559-1567.

Inflammatory Biomarkers and Clinical Judgment in the Emergency Diagnosis of Urgent Abdominal Pain

CLIN CHEM. 2019;65(2):302-312.

Modified HEART Score and High-Sensitivity Cardiac Troponin in Patients With Suspected Acute Myocardial Infarction

J AM COLL CARDIOL. 2019;73(7):873-875.

Predicting Acute Myocardial Infarction with a Single Blood Draw

CLIN CHEM. 2019;65(3):437-450.

Prospective validation of current quantitative electrocardiographic criteria for ST-elevation myocardial infarction

INT J CARDIOL. 2019;292:1-12.

DPP10 is a new regulator of Nav1.5 channels in human heart
Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Künzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kämmerer S
INT J CARDIOL. 2019;284:68-73.

Diagnostic Accuracy of a High-Sensitivity Cardiac Troponin Assay with a Single Serum Test in the Emergency Department
Body R, Twerenbold R, Austin C, Boeddinghaus J, Almashali M, Nestelberger T, Morris N, Badertscher P, McDowell G, Wildi K, Moss P, Rubini Gimenez M, Jarman H, Bigler N, Einemann R, Koechlin L, Pourmahram G, Todd J, Mueller C, Freemont A
CLIN CHEM. 2019;65(8):1006-1014.

Making sense of inhibiting nonsense in hypertrophic cardiomyopathy?
Carrier L
CIRCULATION. 2019;139(6):.

Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model
Castro L, Geertz B, Reinsch M, Aksehirlioglu B, Hansen A, Eschenhagen T, Reichenspurner H, Weinberger F, Pecha S
JOVE-J VIS EXP. 2019;(145):.

Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy
Cordts K, Seelig D, Lund N, Carrier L, Böger R, Avanesov M, Tahir E, Schwedhelm E, Patten M
BIOMOLECULES. 2019;9(7):.

Cysteine-Based Redox Sensing and Its Role in Signaling by Cyclic Nucleotide-Dependent Kinases in the Cardiovascular System
Cuello F, Eaton P
ANNU REV PHYSIOL. 2019;81:63-87.

B-Type Natriuretic Peptides and Cardiac Troponins for Diagnosis and Risk-Stratification of Syncope
du Fay de Lavallaz J, Badertscher P, Nestelberger T, Zimmermann T, Miró Ò, Salgado E, Christ M, Geigy N, Cullen L, Than M, Martin-Sanchez F, Di Somma S, Peacock W, Morawiec B, Walter J, Twerenbold R, Puelacher C, Wussler D, Boeddinghaus J, Koechlin L, Strebel I, Keller D, Lohrmann J, Michou E, Kühne M, Reichlin T, Mueller C
CIRCULATION. 2019.

PKG1α oxidation negatively regulates food seeking behaviour and reward
Duraffourd C, Huckstepp R, Braren I, Fernandes C, Brock O, Delogu A, Prysyazhna O, Burgoyne J, Eaton P
REDOX BIOL. 2019;21:101077.

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors
Eichhoff A, Börner K, Albrecht B, Schäfer W, Baum N, Haag F, Körbelin J, Trepel M, Braren I, Grimm D, Adriouch S, Koch-Nolte F
MOL THER-METH CLIN D. 2019;15:211-220.

Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling
Eiringhaus J, Herting J, Schatter F, Nikolaev V, Sprenger J, Wang Y, Köhn M, Zabel M, El-Armouche A, Hasenfuss G, Sossalla S, Fischer T
BASIC RES CARDIOL. 2019;114(2):13.

Cardiomyopathy phenotypes in human induced pluripotent stem cell-derived cardiomyocytes – a systematic review
Eschenhagen T, Carrier L
PFLUG ARCH EUR J PHY. 2019;471(5):755-768.

Heart Repair With Myocytes: Why not take your own?
Eschenhagen T, Weinberger F
CIRC RES. 2019;124(6):843-845.

Myoarchitectural disarray of hypertrophic cardiomyopathy begins pre-birth
Garcia-Canadilla P, Cook A, Mohun T, Oji O, Schlossarek S, Carrier L, McKenna W, Moon J, Captur G
J ANAT. 2019;235(5):962-976.

DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs
Hoff K, Lemme M, Kahlert A, Runde K, Audain E, Schuster D, Scheewe J, Attmann T, Pickardt T, Caliebe A, Siebert R, Kramer H, Milting H, Hansen A, Ammerpohl O, Hitz M
CLIN EPIGENETICS. 2019;11(1):89.

Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation
Jungen C, Scherschel K, Flenner F, Jee H, Rajendran P, De Jong K, Nikolaev V, Meyer C, Ardell J, Tompkins J
AM J PHYSIOL-HEART C. 2019;317(6):H1328-H1341.

Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis
Kenneweg F, Bang C, Xiao K, Boulanger C, Loyer X, Mazlan S, Schroen B, Hermans-Beijnsberger S, Foinquinos A, Hirt M, Eschenhagen T, Funcke S, Stojanovic S, Genschel C, Schimmel K, Just A, Pfanne A, Scherf K, Dehmel S, Raemon-Buettner S, Fiedler J, Thum T
MOL THER-NUCL ACIDS. 2019;18:363-374.

Relative hypochromia and mortality in acute heart failure
Kleber M, Kozhuharov N, Sabti Z, Glatz B, Isenreich R, Wussler D, Nowak A, Twerenbold R, Badertscher P, Puelacher C, du Fay de Lavallaz J, Nestelberger T, Boeddinghaus J, Wildi K, Flores D, Walter J, Rentsch K, von Eckardstein A, Goudev A, Breidthardt T, Mueller C
INT J CARDIOL. 2019;286:104-110.

Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular non-compaction phenotype
Kolokotronis K, Kühnisch J, Klopocki E, Dartsch J, Rost S, Huculak C, Mearini G, Störk S, Carrier L, Klaassen S, Gerull B
HUM MUTAT. 2019.

Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue
Kresin N, Stücker S, Krämer E, Flenner F, Mearini G, Münch J, Patten M, Redwood C, Carrier L, Friedrich F
FRONT PHYSIOL. 2019;10:239.

Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3
Kühnisch J, Herbst C, Al-Wakeel-Marquard N, Dartsch J, Holtgrewe M, Baban A, Mearini G, Hardt J, Kolokotronis K, Gerull B, Carrier L, Beule D, Schubert S, Messroghli D, Degener F, Berger F, Klaassen S
CLIN GENET. 2019;96(6):549-559.

Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors
Längle D, Werner T, Wesseler F, Reckzeh E, Schaumann N, Drowley L, Polla M, Plowright A, Hirt M, Eschenhagen T, Schade D
CHEMMEDCHEM. 2019;14(8):810-822.

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
Madonna R, Van Laake L, Botker H, Davidson S, De Caterina R, Engel F, Eschenhagen T, Fernandez-Aviles F, Hausenloy D, Hulot J, Lecour S, Leor J, Menasché P, Pesce M, Perrino C, Prunier F, Van Linthout S, Ytrehus K, Zimmermann W, Ferdinandy P, Sluijter J
CARDIOVASC RES. 2019;115(3):488-500.

Piezo-bending actuators for isometric or auxotonic contraction analysis of engineered heart tissue
Mannhardt I, Warncke C, Trieu H, Müller J, Eschenhagen T
J TISSUE ENG REGEN M. 2019;13(1):3-11.

Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy
Morhenn K, Quentin T, Wichmann H, Steinmetz M, Prondzynski M, Söhren K, Christ T, Geertz B, Schröder S, Schöndube F, Hasenfuss G, Schlossarek S, Zimmermann W, Carrier L, Eschenhagen T, Cardinaux J, Lutz S, Oetjen E
J MOL CELL CARDIOL. 2019;127:31-43.

Predicting Major Adverse Events in Patients With Acute Myocardial Infarction.
Nestelberger T, Boeddinghaus J, Wussler D, Twerenbold R, Badertscher P, Wildi K, Miró Ò, López B, Martin-Sanchez F, Muzyk P, Koechlin L, Investigators A
J AM COLL CARDIOL. 2019.

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Pecha S, Yorgan K, Röhl M, Geertz B, Hansen A, Weinberger F, Sehner S, Ehmke H, Reichenspurner H, Eschenhagen T, Schwoerer A
SCI REP-UK. 2019;9(1):9831.

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM
Piroddi N, Witjas-Paalberends E, Ferrara C, Ferrantini C, Vitale G, Scellini B, Wijnker P, Sequiera V, Dooijes D, Dos Remedios C, Schlossarek S, Leung M, Messer A, Ward D, Biggeri A, Tesi C, Carrier L, Redwood C, Marston S, van der Velden J, Poggesi C
J GEN PHYSIOL. 2019;151(1):18-29.

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
Prondzynski M, Lemoine M, Zech A, Horvath A, Di Mauro V, Koivumäki J, Kresin N, Busch J, Krause T, Krämer E, Schlossarek S, Spohn M, Friedrich F, Münch J, Laufer S, Redwood C, Volk A, Hansen A, Mearini G, Catalucci D, Meyer C, Christ T, Patten M, Eschenhagen T, Carrier L
EMBO MOL MED. 2019;11(12):.

Gene therapy strategies in the treatment of hypertrophic cardiomyopathy
Prondzynski M, Mearini G, Carrier L
PFLUG ARCH EUR J PHY. 2019;471(5):807-815.

Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction.
Puelacher C, Gugala M, Adamson P, Shah A, Chapman A, Anand A, Sabti Z, Boeddinghaus J, Nestelberger T, Twerenbold R, Wildi K, Badertscher P, Mueller C
HEART. 2019.

A magnetics-based approach for fine-tuning afterload in engineered heart tissues
Rodriguez M, Werner T, Becker B, Eschenhagen T, Hirt M
ACS BIOMATER SCI ENG. 2019;5(7):3663-3675.

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation
Schaefer A, Schneeberger Y, Schulz S, Krasemann S, Werner T, Piasecki A, Höppner G, Müller C, Morhenn K, Lorenz K, Wieczorek D, Schwoerer A, Eschenhagen T, Ehmke H, Reichenspurner H, Stenzig J, Cuello F
SCI REP-UK. 2019;9(1):5710.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation
Scherschel K, Hedenus K, Jungen C, Lemoine M, Rübsamen N, Veldkamp M, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C
SCI TRANSL MED. 2019;11(493):.

Dissecting hiPSC-CM pacemaker function in a cardiac organoid model
Schulze M, Lemoine M, Fischer A, Scherschel K, David R, Riecken K, Hansen A, Eschenhagen T, Ulmer B
BIOMATERIALS. 2019;206:133-145.

Effect of ranolazine on plasma arginine derivatives and urinary isoprostane 8-iso-PGF2α in patients with myocardial infarction in the randomized RIMINI-Trial
Schwemer T, Deutscher N, Diermann N, Böger R, Schwedhelm E, Blankenberg S, Friedrich F
SCI REP-UK. 2019;9(1):5708.

Effect of Ranolazine on Ischemic Myocardium IN Patients With Acute Cardiac Ischemia (RIMINI-Trial): A Randomized Controlled Pilot Trial
Schwemer T, Radziwolek L, Deutscher N, Diermann N, Sehner S, Blankenberg S, Friedrich F
J CARDIOVASC PHARM T. 2019;24(1):62-69.

Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes
Stathopoulou K, Schobesberger S, Bork N, Sprenger J, Perera R, Sotoud H, Geertz B, David J, Christ T, Nikolaev V, Cuello F
CELL SIGNAL. 2019;63:109362.

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management
Thomas D, Christ T, Fabritz L, Goette A, Hammwöhner M, Heijman J, Kockskämper J, Linz D, Odening K, Schweizer P, Wakili R, Voigt N
CLIN RES CARDIOL. 2019;108(6):577-599.

Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium
Trautsch I, Heta E, Soong P, Levent E, Nikolaev V, Bogeski I, Katschinski D, Mayr M, Zimmermann W
FRONT PHYSIOL. 2019;10:272.

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
van Meer B, Krotenberg A, Sala L, Davis R, Eschenhagen T, Denning C, Tertoolen L, Mummery C
NAT COMMUN. 2019;10(1):4325.

A newly generated neuronal cell model of CLN7 disease reveals aberrant lysosome motility and impaired cell survival.
von Kleist L, Ariunbat K, Braren I, Stauber T, Storch S, Danyukova T
MOL GENET METAB. 2019;126(2):196-205.

Blockade of miR-140-3p prevents functional deterioration in afterload-enhanced engineered heart tissue
Werner T, Kunze A, Stenzig J, Eschenhagen T, Hirt M
SCI REP-UK. 2019;9(1):11494.

Impact of Food and Drug Administration Regulatory Approach on the 0/2-Hour Algorithm for Rapid Triage of Suspected Myocardial Infarction
Wildi K, Nestelberger T, Wussler D, Boeddinghaus J, Badertscher P, Koechlin L, Duwe P, Rubini Gimenez M, Twerenbold R, Mueller C
CIRC-CARDIOVASC QUAL. 2019;12(1):e005188.

External Validation of the MEESSI Acute Heart Failure Risk Score: A Cohort Study
Wussler D, Kozhuharov N, Sabti Z, Walter J, Strebel I, Scholl L, Miró O, Rossello X, Martín-Sánchez F, Pocock S, Nowak A, Badertscher P, Twerenbold R, Wildi K, Puelacher C, du Fay de Lavallaz J, Shrestha S, Strauch O, Flores D, Nestelberger T, Boeddinghaus J, Schumacher C, Goudev A, Pfister O, Breidthardt T, Mueller C
ANN INTERN MED. 2019;170(4):248-256.

Diagnostic accuracy of the aortic dissection detection risk score plus D-dimer for acute aortic syndromes the ADvISED prospective multicenter study

CIRCULATION. 2018;137(3):250-258.

The Effect of L. Fruit Juice on the Blood Sugar Level and Other Serum Parameters in Patients with Diabetes Type 2
Algenstaedt P, Stumpenhagen A, Westendorf J
EVID-BASED COMPL ALT. 2018;2018:3565427.

Direct Comparison of the 0/1h and 0/3h Algorithms for Early Rule-Out of Acute Myocardial Infarction
Badertscher P, Boeddinghaus J, Twerenbold R, Nestelberger T, Wildi K, Wussler D, Schwarz J, Puelacher C, Rubini Giménez M, Kozhuharov N, du Fay de Lavallaz J, Cerminara S, Potlukova E, Rentsch K, Miró Ò, López B, Martin-Sanchez F, Morawiec B, Muzyk P, Keller D, Reichlin T, Mueller C
CIRCULATION. 2018;137(23):2536-2538.

S100A4 as a target of the E3-ligase Asb2β and its effect on engineered heart tissue
Braumann S, Thottakara T, Stücker S, Reischmann-Düsener S, Krämer E, Groß J, Hirt M, Doroudgar S, Carrier L, Friedrich F
FRONT PHYSIOL. 2018;9:1292.

How accurate is clinical assessment of neck veins in the estimation of central venous pressure in acute heart failure? Insights from a prospective study
Breidthardt T, Moreno-Weidmann Z, Uthoff H, Sabti Z, Aeppli S, Puelacher C, Stallone F, Twerenbold R, Wildi K, Kozhuharov N, Wussler D, Flores D, Shrestha S, Badertscher P, Boeddinghaus J, Nestelberger T, Gimenez M, Staub D, Aschwanden M, Lohrmann J, Pfister O, Osswald S, Mueller C
EUR J HEART FAIL. 2018;20(7):1160-1162.

Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks
Brenière-Letuffe D, Domke-Shibamiya A, Hansen A, Eschenhagen T, Fehse B, Riecken K, Stenzig J
STEM CELL RES THER. 2018;9(1):165.

Pharmakologie der Antihypotensiva
Christ T, Uzun A
2018. Anästhesiologie. 56. Aufl. Landsberg/Lech: EcoMed, 1-10.

Oxidation of cardiac myofilament proteins: Priming for dysfunction?
Cuello F, Wittig I, Lorenz K, Eaton P
MOL ASPECTS MED. 2018;63(SI):47-58.

A new concept of fibroblast dynamics in post-myocardial infarction remodeling
Eschenhagen T
J CLIN INVEST. 2018;128(5):1731-1733.

Calciumantagonisten
Eschenhagen T
2018. Arzneiverordnungs-Report 2018. Schwabe U, Paffrath D, Ludwig W, Klauber J (Hrsg.). 1. Aufl. Springer-Verlag Berlin, Heidelberg, 467-473.

Exaggerated Cardiotoxicity of Sunitinib in Stressed 3-Dimensional Heart Muscles
Eschenhagen T
JACC-BASIC TRANSL SC. 2018;3(2):277-279.

From basic science to high performance medicine
Eschenhagen T
EUR HEART J. 2018;39(32):2919-2921.

Herztherapeutika
Eschenhagen T
2018. Arzneiverordnungs-Report 2018. Schwabe U, Paffrath D, Ludwig W, Klauber J (Hrsg.). 1. Aufl. Springer-Verlag Berlin, Heidelberg, 539-552.

Kardiologie 2018: Von der Grundlagenforschung zur Hochleistungsmedizin
Eschenhagen T
HERZ. 2018;43(2):101-102.

Therapy of Heart Failure
Eschenhagen T
2018. Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e. 13. Aufl. New York: 527-546.

Treatment of Hypertension
Eschenhagen T
2018. Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e. 13. Aufl. New York: McGraw-Hill, New York, 507-526.

Treatment of ischemic heart disease
Eschenhagen T
2018. Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e. 13. Aufl. New York: McGraw-Hill, New York, 489-506.

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but not to Ca2+ Handling or β-Adrenoceptor Signaling
Flenner F, Arlt N, Nasib M, Schobesberger S, Koch T, Ravens U, Friedrich F, Nikolaev V, Christ T, Stehr S
ANESTHESIOLOGY. 2018;128(6):1175-1186.

Novel DNA Methylation Sites Influence Expression in Relation to Smoking
Haase T, Müller C, Krause J, Röthemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild P, Michal M, Marini F, Karakas M, Lackner K, Blankenberg S, Zeller T
BIOMOLECULES. 2018;8(3):E74.

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes
Horváth A, Lemoine M, Löser A, Mannhardt I, Flenner F, Uzun A, Neuber C, Breckwoldt K, Hansen A, Girdauskas E, Reichenspurner H, Willems S, Jost N, Wettwer E, Eschenhagen T, Christ T
STEM CELL REP. 2018;10(3):822-833.

Correction: Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue
Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt M, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A
PLOS ONE. 2018;13(11):e0208342.

Response by Kaier et al to Letter Regarding Article, "Direct Comparison of Cardiac Myosin-Binding Protein C With Cardiac Troponins for the Early Diagnosis of Acute Myocardial Infarction"
Kaier T, Twerenbold R, Puelacher C, Marjot J, Imambaccus N, Boeddinghaus J, Nestelberger T, Badertscher P, Sabti Z, Rubini Giménez M, Wildi K, Hillinger P, Grimm K, Loeffel S, Shrestha S, Flores Widmer D, Cupa J, Kozhuharov N, Miró Ò, Martín-Sánchez F, Morawiec B, Rentsch K, Lohrmann J, Kloos W, Osswald S, Reichlin T, Weber E, Marber M, Mueller C
CIRCULATION. 2018;138(5):544-545.

Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase
Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi G, Aytekin M, Dweik R, Hennigs J, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph T, Hazen S, Klose H, Schermuly R, Rudolph V, Baldus S
JCI INSIGHT. 2018;3(11):.

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology
Krause J, Löser A, Lemoine M, Christ T, Scherschel K, Meyer C, Blankenberg S, Zeller T, Eschenhagen T, Stenzig J
BASIC RES CARDIOL. 2018;113(5):41.

A fragment of adhesion molecule L1 is imported into mitochondria, and regulates mitochondrial metabolism and trafficking.
Kraus K, Kleene R, Braren I, Loers G, Lutz D, Schachner M
J CELL SCI. 2018;131(9):UNSP jcs210500.

A Fragment of Adhesion Molecule L1 Binds to Nuclear Receptors to Regulate Synaptic Plasticity and Motor Coordination
Kraus K, Kleene R, Henis M, Braren I, Kataria H, Sharaf A, Loers G, Schachner M, Lutz D
MOL NEUROBIOL. 2018;55(9):7164-7178.

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium
Lemme M, Ulmer B, Lemoine M, Zech A, Flenner F, Ravens U, Reichenspurner H, Rol-Garcia M, Smith G, Hansen A, Christ T, Eschenhagen T
STEM CELL REP. 2018;11(6):1378-1390.

Human Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers
Lemoine M, Krause T, Koivumäki J, Prondzynski M, Schulze M, Girdauskas E, Willems S, Hansen A, Eschenhagen T, Christ T
CIRC-ARRHYTHMIA ELEC. 2018;11(7):e006035.

Treatments targeting inotropy: A position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
Maack C, Eschenhagen T, Hamdani N, Heinzel F, Lyon A, Manstein D, Metzger J, Papp Z, Tocchetti C, Yilmaz M, Anker S, Balligand J, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland J, de Boer R, Dietl A, Fischmeister R, Harjola V, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke W, Lund L, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic P, Skouri H, Zimmermann W, Mebazaa A
EUR HEART J. 2018.

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering
Maffioletti S, Sarcar S, Henderson A, Mannhardt I, Pinton L, Moyle L, Steele-Stallard H, Cappellari O, Wells K, Ferrari G, Mitchell J, Tyzack G, Kotiadis V, Khedr M, Ragazzi M, Wang W, Duchen M, Patani R, Zammit P, Wells D, Eschenhagen T, Tedesco F
CELL REP. 2018;23(3):899-908.

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
Mosqueira D, Mannhardt I, Bhagwan J, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M, Harmer S, Tinker A, Smith J, Carrier L, Williams P, Gaffney D, Eschenhagen T, Hansen A, Denning C
EUR HEART J. 2018;39(43):3879-3892.

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart
Neidig L, Weinberger F, Palpant N, Mignone J, Martinson A, Sorensen D, Bender I, Nemoto N, Reinecke H, Pabon L, Molkentin J, Murry C, van Berlo J
CIRCULATION. 2018;138(25):2960-2962.

Normalization of force to muscle cross-sectional area: A helpful attempt to reduce data scattering in contractility studies?
Pecha S, Koivumäki J, Geelhoed B, Kempe R, Berk E, Engel A, Reichenspurner H, Eschenhagen T, Ravens U, Kaumann A, Christ T
ACTA PHYSIOL. 2018;224(4):e13202.

Satellite cells delivered in their niche efficiently generate functional myotubes in three-dimensional cell culture
Prüller J, Mannhardt I, Eschenhagen T, Zammit P, Figeac N
PLOS ONE. 2018;13(9):e0202574.

Stammzellbasierte kardiale Regeneration nach Infarkt
Reinsch M, Weinberger F
HERZ. 2018;43(2):109-114.

Impact of the US Food and Drug Administration-Approved Sex-Specific Cutoff Values for High-Sensitivity Cardiac Troponin T to Diagnose Myocardial Infarction
Rubini Gimenez M, Badertscher P, Twerenbold R, Boeddinghaus J, Nestelberger T, Wussler D, Miró Ò, Martín-Sánchez F, Reichlin T, Mueller C
CIRCULATION. 2018;137(17):1867-1869.

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation
Skibsbye L, Bengaard A, Uldum-Nielsen A, Boddum K, Christ T, Jespersen T
FRONT PHYSIOL. 2018;9:510.

Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTCI E99K Mutation Unveil Differential Functional Deficits
Smith J, Owen T, Bhagwan J, Mosqueira D, Scott E, Mannhardt I, Patel A, Barriales-Villa R, Monserrat L, Hansen A, Eschenhagen T, Harding S, Marston S, Denning C
STEM CELL REP. 2018;11(5):1226-1243.

Lokalanästhetika und Lipid Rescue
Stehr S, Christ T
2018. Praxis der Anästhesiologie. Wilhelm W (Hrsg.). 1. Aufl. Berlin: Springer, 445-456.

Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
Stenzig J, Schneeberger Y, Löser A, Peters B, Schäfer A, Zhao R, Ng S, Höppner G, Geertz B, Hirt M, Tan W, Wong E, Reichenspurner H, Foo R, Eschenhagen T
J MOL CELL CARDIOL. 2018;120:53-63.

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes
Ulmer B, Stoehr A, Schulze M, Patel S, Gucek M, Mannhardt I, Funcke S, Murphy E, Eschenhagen T, Hansen A
STEM CELL REP. 2018;10(3):834-847.

No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart
Weinberger F, Nicol P, Starbatty J, Stubbendorff M, Becher P, Schrepfer S, Eschenhagen T
PHARMACOL RES PERSPE. 2018;6(3):e00407.

Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling
Zhao R, Ackers-Johnson M, Stenzig J, Chen C, Ding T, Zhou Y, Wang P, Ng S, Li P, Teo G, Rudd P, Fawcett J, Foo R
CIRCULATION. 2018;137(23):2497-2513.

Diagnostic and prognostic values of the V-index, a novel ECG marker quantifying spatial heterogeneity of ventricular repolarization, in patients with symptoms suggestive of non-ST-elevation myocardial infarction
Abächerli R, Twerenbold R, Boeddinghaus J, Nestelberger T, Mächler P, Sassi R, Rivolta M, Roonizi E, Mainardi L, Kozhuharov N, Rubini Giménez M, Wildi K, Grimm K, Sabti Z, Hillinger P, Puelacher C, Strebel I, Cupa J, Badertscher P, Roux I, Schmid R, Leber R, Osswald S, Mueller C, Reichlin T
INT J CARDIOL. 2017;236:23-29.

Letter to the Editor: "High sensitive cardiac troponin T: Testing the test"
Badertscher P, Boeddinghaus J, Nestelberger T, Giménez M, Twerenbold R, Mueller C
INT J CARDIOL. 2017;234:126.

Cafedrine/Theodrenaline (20:1) Is an Established Alternative for the Management of Arterial Hypotension in Germany-a Review Based on a Systematic Literature Search
Bein B, Christ T, Eberhart L
FRONT PHARMACOL. 2017;8:1-8, Art 68.

Direct comparison of 4 very early rule-out strategies for acute myocardial infarction using high-sensitivity cardiac troponin i
Boeddinghaus J, Nestelberger T, Twerenbold R, Wildi K, Badertscher P, Cupa J, Bürge T, Mächler P, Corbière S, Grimm K, Giménez M, Puelacher C, Shrestha S, Widmer D, Fuhrmann J, Hillinger P, Sabti Z, Honegger U, Schaerli N, Kozhuharov N, Rentsch K, Miró Ò, López B, Martin-Sanchez F, Rodriguez-Adrada E, Morawiec B, Kawecki D, Ganovská E, Parenica J, Lohrmann J, Kloos W, Buser A, Geigy N, Keller D, Osswald S, Reichlin T, Mueller C
CIRCULATION. 2017;135(17):1597-1611.

Early diagnosis of acute myocardial infarction in patients with mild elevations of cardiac troponin
Boeddinghaus J, Reichlin T, Nestelberger T, Twerenbold R, Meili Y, Wildi K, Hillinger P, Giménez M, Cupa J, Schumacher L, Schubera M, Badertscher P, Corbière S, Grimm K, Puelacher C, Sabti Z, Widmer D, Schaerli N, Kozhuharov N, Shrestha S, Bürge T, Mächler P, Büchi M, Rentsch K, Miró Ò, López B, Martin-Sanchez F, Rodriguez-Adrada E, Morawiec B, Kawecki D, Ganovská E, Parenica J, Lohrmann J, Buser A, Keller D, Osswald S, Mueller C
CLIN RES CARDIOL. 2017;106(6):457-467.

Differentiation of cardiomyocytes and generation of human engineered heart tissue
Breckwoldt K, Letuffe-Brenière D, Mannhardt I, Schulze T, Ulmer B, Werner T, Benzin A, Klampe B, Reinsch M, Laufer S, Shibamiya A, Prondzynski M, Mearini G, Schade D, Fuchs S, Neuber C, Krämer E, Saleem U, Schulze M, Rodriguez M, Eschenhagen T, Hansen A
NAT PROTOC. 2017;12(6):1177-1197.

Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity
Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King S, Nikolaev V, de Wit C, Leichert L, Feil R, Eaton P, Cuello F
SCI REP-UK. 2017;7(1):9938.

Cardiomyocyte Regeneration: A Consensus Statement
Eschenhagen T, Bolli R, Braun T, Field L, Fleischmann B, Frisén J, Giacca M, Hare J, Houser S, Lee R, Marbán E, Martin J, Molkentin J, Murry C, Riley P, Ruiz-Lozano P, Sadek H, Sussman M, Hill J
CIRCULATION. 2017;136(7):680-686.

Myocardial Repair
Eschenhagen T, Breckwoldt K
2017. Encyclopedia of Cardiovascular Research and Medicine. Vasan R, Sawyer D (Hrsg.). 1. Aufl. Elsevier, 425 - 439.

Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice
Flenner F, Geertz B, Reischmann S, Weinberger F, Eschenhagen T, Carrier L, Friedrich F
J PHYSIOL-LONDON. 2017;595(12):3987-3999.

Risk stratification of patients with left atrial appendage thrombus prior to catheter ablation of atrial fibrillation: An approach towards an individualized use of transesophageal echocardiography
Gunawardene M, Dickow J, Schaeffer B, Akbulak R, Lemoine M, Nührich J, Jularic M, Sinning C, Eickholt C, Meyer C, Moser J, Hoffmann B, Willems S
J CARDIOVASC ELECTR. 2017;28(10):1127-1136.

Cardiovascular Research in Germany
Heusch G, Eschenhagen T, Dimmeler S
CIRC RES. 2017;121(5):492-495.

Akrinor(TM), a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro
Kloth B, Pecha S, Moritz E, Schneeberger Y, Söhren K, Schwedhelm E, Reichenspurner H, Eschenhagen T, Böger R, Christ T, Stehr S
FRONT PHARMACOL. 2017;8:272.

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density
Lemoine M, Mannhardt I, Breckwoldt K, Prondzynski M, Flenner F, Ulmer B, Hirt M, Neuber C, Horváth A, Kloth B, Reichenspurner H, Willems S, Hansen A, Eschenhagen T, Christ T
SCI REP-UK. 2017;7(1):5464.

An algorithm for rule-in and rule-out of acute myocardial infarction using a novel troponin i assay
Lindahl B, Jernberg T, Badertscher P, Boeddinghaus J, Eggers K, Frick M, Rubini Gimenez M, Linder R, Ljung L, Martinsson A, Melki D, Nestelberger T, Rentsch K, Reichlin T, Sabti Z, Schubera M, Svensson P, Twerenbold R, Wildi K, Mueller C
HEART. 2017;103(2):125-131.

Blinded contractility analysis in hiPSC-cardiomyocytes in engineered heart tissue format: Comparison with human atrial trabeculae
Mannhardt I, Eder A, Dumotier B, Prondzynski M, Krämer E, Traebert M, Söhren K, Flenner F, Stathopoulou K, Lemoine M, Carrier L, Christ T, Eschenhagen T, Hansen A
TOXICOL SCI. 2017;158(1):164-175.

Perfusion Bioreactors for Prevascularization Strategies in Cardiac Tissue Engineering
Mannhardt I, Marsano A, Teuschl A
2017 [Epub ahead of print]. Reference Series in Biomedical Engineering. Holnthoner W, Banfi A, Kirkpatrick J, Redl H (Hrsg.). Springer International Publishing, 1-14.

Automated Contraction Analysis of Human Engineered Heart Tissue for Cardiac Drug Safety Screening
Mannhardt I, Saleem U, Benzin A, Schulze T, Klampe B, Eschenhagen T, Hansen A
JOVE-J VIS EXP. 2017;122:e55461.

Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling
Mollenhauer M, Friedrichs K, Lange M, Gesenberg J, Remane L, Kerkenpaß C, Krause J, Schneider J, Ravekes T, Maass M, Halbach M, Peinkofer G, Saric T, Mehrkens D, Adam M, Deuschl F, Lau D, Geertz B, Manchanda K, Eschenhagen T, Kubala L, Rudolph T, Wu Y, Tang W, Hazen S, Baldus S, Klinke A, Rudolph V
CIRC RES. 2017;121(1):56-70.

Prominent differences in left ventricular performance and myocardial properties between right ventricular and left ventricular-based pacing modes in rats.
Mulla W, Etzion S, Elyagon S, Gillis R, Murninkas M, Konstantino Y, Mannhardt I, Eschenhagen T, Liel-Cohen N, Etzion Y
SCI REP-UK. 2017;7(1):5931.

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes
Prondzynski M, Krämer E, Laufer S, Domke-Shibamiya A, Pless O, Flenner F, Müller O, Münch J, Redwood C, Hansen A, Patten-Hamel M, Eschenhagen T, Mearini G, Carrier L
MOL THER-NUCL ACIDS. 2017;7:475-486.

Diagnostic value of ST-segment deviations during cardiac exercise stress testing: Systematic comparison of different ECG leads and time-points
Puelacher C, Wagener M, Abächerli R, Honegger U, Lhasam N, Schaerli N, Prêtre G, Strebel I, Twerenbold R, Boeddinghaus J, Nestelberger T, Rubini Giménez M, Hillinger P, Wildi K, Sabti Z, Badertscher P, Cupa J, Kozhuharov N, du Fay de Lavallaz J, Freese M, Roux I, Lohrmann J, Leber R, Osswald S, Wild D, Zellweger M, Mueller C, Reichlin T
INT J CARDIOL. 2017;238:166-172.

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.
Sala L, van Meer B, Tertoolen L, Bakkers J, Bellin M, Davies R, Denning C, Dieben M, Eschenhagen T, Giacomelli E, Grandela C, Hansen A, Holman E, Jongbloed M, Kamel S, Koopman C, Lachaud Q, Mannhardt I, Mol M, Mosqueira D, Orlova V, Passier R, Ribeiro M, Saleem U, Smith G, Burton F, Mummery C
CIRC RES. 2017.

A new negative allosteric modulator, AP14145, for the study of small conductance calcium-activated potassium (K2) channels
Simó-Vicens R, Kirchhoff J, Dolce B, Abildgaard L, Speerschneider T, Sørensen U, Grunnet M, Diness J, Bentzen B
BRIT J PHARMACOL. 2017;174(23):4396-4408.

Activation of autophagy ameliorates cardiomyopathy in Mybpc3-targeted knock-in mice
Singh S, Zech A, Geertz B, Reischmann S, Osinska H, Prondzynski M, Krämer E, Meng Q, Redwood C, van der Velden J, Robbins J, Schlossarek S, Carrier L
CIRC-HEART FAIL. 2017;10(10):e004140.

Nebivolol Desensitizes Myofilaments of a Hypertrophic Cardiomyopathy Mouse Model: Nebivolol Desensitizes Mouse HCM Myofilaments
Stücker S, Kresin N, Carrier L, Friedrich F
FRONT PHYSIOL. 2017;8:558.

Engineering Cardiac Muscle Tissue: A Maturating Field of Research
Weinberger F, Mannhardt I, Eschenhagen T
CIRC RES. 2017;120(9):1487-1500.

Direct Comparison of 2 Rule-Out Strategies for Acute Myocardial Infarction: 2-h Accelerated Diagnostic Protocol vs 2-h Algorithm
Wildi K, Cullen L, Twerenbold R, Greenslade J, Parsonage W, Boeddinghaus J, Nestelberger T, Sabti Z, Rubini-Giménez M, Puelacher C, Cupa J, Schumacher L, Badertscher P, Grimm K, Kozhuharov N, Stelzig C, Freese M, Rentsch K, Lohrmann J, Kloos W, Buser A, Reichlin T, Pickering J, Than M, Mueller C
CLIN CHEM. 2017;63(7):1227-1236.

Thymosin4 Improves Differentiation and Vascularization of EHTs
Ziegler T, Hinkel R, Stöhr A, Eschenhagen T, Laugwitz K, le Noble F, David R, Hansen A, Kupatt C
Stem Cells Int. 2017;2017:6848271.

Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis
Aherrahrou Z, Schlossarek S, Stoelting S, Klinger M, Geertz B, Weinberger F, Kessler T, Aherrahou R, Moreth K, Bekeredjian R, Hrabě de Angelis M, Just S, Rottbauer W, Eschenhagen T, Schunkert H, Carrier L, Erdmann J
BASIC RES CARDIOL. 2016;111(1):6-6.

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation
Barallobre-Barreiro J, Gupta S, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt M, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah A, Jahangiri M, Schaefer L, Fischer J, Iozzo R, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M
CIRCULATION. 2016;134(11):817-32.

In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias
Berk E, Christ T, Schwarz S, Ravens U, Knaut M, Kaumann A
BRIT J PHARMACOL. 2016;173(16):2478-89.

Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation
Biermann D, Eder A, Arndt F, Seoudy H, Reichenspurner H, Mir T, Riso A, Kozlik-Feldmann R, Peldschus K, Kaul M, Schuler T, Krasemann S, Hansen A, Eschenhagen T, Sachweh J
PLOS ONE. 2016;11(11):e0166963.

Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice
Bögeholz N, Pauls P, Kaese S, Schulte J, Lemoine M, Dechering D, Frommeyer G, Goldhaber J, Seidl M, Kirchhefer U, Eckardt L, Müller F, Pott C
J MOL CELL CARDIOL. 2016;101:106-115.

Heart regeneration
Breckwoldt K, Weinberger F, Eschenhagen T
BBA-MOL CELL RES. 2016;1863(7 Pt B):1749-59.

The embryological basis of subclinical hypertrophic cardiomyopathy
Captur G, Ho C, Schlossarek S, Kerwin J, Mirabel M, Wilson R, Rosmini S, Obianyo C, Reant P, Basset P, Cook A, Lindsay S, McKenna W, Mills K, Elliott P, Mohun T, Carrier L, Moon J
SCI REP-UK. 2016;6:27714.

Block of Na(+)/Ca(2+) exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation
Christ T, Kovács P, Acsai K, Knaut M, Eschenhagen T, Jost N, Varró A, Wettwer E, Ravens U
EUR J PHARMACOL. 2016;788:286-93.

Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?
Cuello F, Lorenz K
BASIC RES CARDIOL. 2016;111(6):66.

Human engineered heart tissue as a model system for drug testing
Eder A, Vollert I, Hansen A, Eschenhagen T
ADV DRUG DELIVER REV. 2016;96:214-24.

Is Stimulation of Cardiomyocyte Renewal a Facette of Reversible Catecholamine Toxicity?
Eschenhagen T
CIRC RES. 2016;119(7):779-81.

Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy
Flenner F, Friedrich F, Ungeheuer N, Christ T, Geertz B, Reischmann S, Wagner S, Stathopoulou K, Söhren K, Weinberger F, Schwedhelm E, Cuello F, Maier L, Eschenhagen T, Carrier L
CARDIOVASC RES. 2016;109(1):90-102.

Epigallocatechin-3-gallate accelerates relaxation and Ca²⁺ transient decay and desensitizes myofilaments in healthy and cardiomyopathic Mybpc3-targeted knock-in mice
Friedrich F, Flenner F, Nasib M, Eschenhagen T, Carrier L
FRONT PHYSIOL. 2016;7:607.

Gender-specific uncertainties in the diagnosis of acute coronary syndrome.
Hillinger P, Twerenbold R, Wildi K, Rubini G, Jaeger C, Boeddinghaus J, Nestelberger T, Grimm K, Reichlin T, Stallone F, Puelacher C, Sabti Z, Kozhuharov N, Honegger U, Ballarino P, Miro O, Denhaerynck K, Ekrem T, Kohler C, Bingisser R
CLIN RES CARDIOL. 2016;2017(106):28-37.

General practitioners' adherence to chronic heart failure guidelines regarding medication: the GP-HF study
Hirt M, Muttardi A, Helms T, Bussche van den H, Eschenhagen T
CLIN RES CARDIOL. 2016;105(5):441-50.

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue
Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt M, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A
PLOS ONE. 2016;11(2):e0145937.

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure
Madonna R, Van Laake L, Davidson S, Engel F, Hausenloy D, Lecour S, Leor J, Perrino C, Schulz R, Ytrehus K, Landmesser U, Mummery C, Janssens S, Willerson J, Eschenhagen T, Ferdinandy P, Sluijter J
EUR HEART J. 2016;37(23):1789-98.

Human Engineered Heart Tissue: Analysis of Contractile Force
Mannhardt I, Breckwoldt K, Letuffe-Brenière D, Schaaf S, Schulz H, Neuber C, Benzin A, Werner T, Eder A, Schulze T, Klampe B, Christ T, Hirt M, Huebner N, Moretti A, Eschenhagen T, Hansen A
STEM CELL REP. 2016;7(1):29-42.

PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction
Muhammad E, Levitas A, Levitas A, Singh S, Braiman A, Ofir R, Etzion S, Sheffield V, Etzion Y, Carrier L, Parvari R
HUM MOL GENET. 2016;24(25):7227-7240.

Serum Matrix Metalloproteinases as Quantitative Biomarkers for Myocardial Fibrosis and Sudden Cardiac Death Risk Stratification in Patients With Hypertrophic Cardiomyopathy
Münch J, Avanesov M, Bannas P, Säring D, Krämer E, Mearini G, Carrier L, Suling A, Lund G, Patten-Hamel M
J CARD FAIL. 2016;22(10):845-50.

Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model
Najafi A, Sequeira V, Helmes M, Bollen I, Goebel M, Regan J, Carrier L, Kuster D, van der Velden J
CARDIOVASC RES. 2016;110(2):200-14.

Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains
Offermann N, Plum M, Hübner U, Rathloff K, Braren I, Fooke M, Spillner E
ALLERGY. 2016;71(12):1794-1799.

Exogenous Nitric Oxide Protects Human Embryonic Stem Cell-Derived Cardiomyocytes against Ischemia/Reperfusion Injury
Pálóczi J, Varga Z, Apáti Á, Szebényi K, Sarkadi B, Madonna R, De Caterina R, Csont T, Eschenhagen T, Ferdinandy P, Görbe A
OXID MED CELL LONGEV. 2016;2016:4298945.

Myocardial tissue engineering for cardiac repair
Pecha S, Eschenhagen T, Reichenspurner H
J HEART LUNG TRANSPL. 2016;35(3):294-298.

A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation
Schaefer A, Schneeberger Y, Stenzig J, Biermann D, Jelinek M, Reichenspurner H, Eschenhagen T, Ehmke H, Schwoerer A
PLOS ONE. 2016;11(2):e0148259.

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia
Schäfer M, Oeing C, Rohm M, Baysal-Temel E, Lehmann L, Bauer R, Volz H, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt M, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus H, Berriel Diaz M, Backs J, Herzig S
MOL METAB. 2016;5(2):67-78.

Pharmacokinetics of the Experimental Non-Nucleosidic DNA Methyl Transferase Inhibitor N-Phthalyl-l-Tryptophan (RG 108) in Rats
Schneeberger Y, Stenzig J, Hübner F, Schaefer A, Reichenspurner H, Eschenhagen T
BASIC CLIN PHARMACOL. 2016;118(5):327-332.

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin E, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock M, Marber M, Conte M, Greenstein A, Greensmith D, Venetucci L, Timms J, Eaton P
NAT COMMUN. 2016;7:13187.

Refractoriness in human atria: Time and voltage dependence of sodium channel availability
Skibsbye L, Jespersen T, Christ T, Maleckar M, van den Brink J, Tavi P, Koivumäki J
J MOL CELL CARDIOL. 2016;101:26-34.

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure
Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker P, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F
FASEB J. 2016;30(5):1849-64.

DNA Methylation in Heart Failure
Stenzig J, Foo R
2016. Epigenetics in Cardiac Disease. Backs J, McKinsey T (Hrsg.). 1. Aufl. Springer International Publishing, 75 - 102.

DNA methylation in an engineered heart tissue model of cardiac hypertrophy: common signatures and effects of DNA methylation inhibitors
Stenzig J, Hirt M, Löser A, Bartholdt L, Hensel J, Werner T, Riemenschneider M, Indenbirken D, Guenther T, Müller C, Hübner N, Stoll M, Eschenhagen T
BASIC RES CARDIOL. 2016;111(1):9.

Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue
Stoehr A, Hirt M, Hansen A, Seiffert M, Conradi L, Uebeler J, Limbourg F, Eschenhagen T
TISSUE ENG PT A. 2016;22(3-4):326-35.

Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions
Uzun A, Mannhardt I, Breckwoldt K, Horváth A, Johannsen S, Hansen A, Eschenhagen T, Christ T
FRONT PHARMACOL. 2016;7:300.

Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis
Wang X, Gkanatsas Y, Palasubramaniam J, Hohmann J, Chen Y, Lim B, Hagemeyer C, Peter K
THERANOSTICS. 2016;6(5):726-38.

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells
Weinberger F, Breckwoldt K, Pecha S, Kelly A, Geertz B, Starbatty J, Yorgan T, Cheng K, Lessmann K, Stolen T, Scherrer-Crosbie M, Smith G, Reichenspurner H, Hansen A, Eschenhagen T
SCI TRANSL MED. 2016;8(363):363ra148.

Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue
Wijnker P, Friedrich F, Dutsch A, Reischmann S, Eder A, Mannhardt I, Mearini G, Eschenhagen T, van der Velden J, Carrier L
J MOL CELL CARDIOL. 2016;97:82-92.

Outcomes of Patients in Long-Term Opioid Maintenance Treatment
Zippel-Schultz B, Specka M, Cimander K, Eschenhagen T, Gölz J, Maryschok M, Nowak M, Poehlke T, Stöver H, Helms T, Scherbaum N
SUBST USE MISUSE. 2016;51(11):1493-503.

Serum levels of nimodipine in enteral and parenteral administration in patients with aneurysmal subarachnoid hemorrhage
Abboud T, Andresen-Streichert H, Koeppen J, Czorlich P, Dührsen L, Stenzig J, Westphal M, Regelsberger J
ACTA NEUROCHIR. 2015;157(5):763-767.

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology
Carrier L, Mearini G, Stathopoulou K, Cuello F
GENE. 2015;573(2):188-197.

LQT1-phenotypes in hiPSC: Are we measuring the right thing?
Christ T, Horvath A, Eschenhagen T
P NATL ACAD SCI USA. 2015;112(16):E1968.

Prolonged action potentials in HCM-derived iPSC - biology or artefact?
Christ T, Koivumäki J, Eschenhagen T
CARDIOVASC RES. 2015;106(1):6.

Treatment of Atrial Flutter and Atrial Fibrillation
Christ T, Pecha S, Jost N
2015. Pathophysiology and Pharmacotherapy of Cardiovascular Disease. Jagadeesh G, Balakumar P, Maung-U K (Hrsg.). 1. Aufl. Adis, 1059 - 1079.

Immunobiology of fibrin-based engineered heart tissue
Conradi L, Schmidt S, Neofytou E, Deuse T, Peters L, Eder A, Hua X, Hansen A, Robbins R, Beygui R, Reichenspurner H, Eschenhagen T, Schrepfer S
STEM CELL TRANSL MED. 2015;4(6):625-631.

Animal and in silico models for the study of sarcomeric cardiomyopathies
Duncker D, Bakkers J, Brundel B, Robbins J, Tardiff J, Carrier L
CARDIOVASC RES. 2015;105(4):439-48.

Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes
Eschenhagen T, Mummery C, Knollmann B
CARDIOVASC RES. 2015;105(4):424-38.

Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization
Fiedler J, Breckwoldt K, Remmele C, Hartmann D, Dittrich M, Pfanne A, Just A, Xiao K, Kunz M, Müller T, Hansen A, Geffers R, Dandekar T, Eschenhagen T, Thum T
J AM COLL CARDIOL. 2015;66(18):2005-15.

I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model
Friedrich F, Sotoud H, Geertz B, Weber S, Flenner F, Reischmann S, Eschenhagen T, Carrier L, El-Armouche A
IJC HEART VASC. 2015;8:87-94.

Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy
Gehmlich K, Dodd M, Allwood J, Kelly M, Bellahcene M, Lad H, Stockenhuber A, Hooper C, Ashrafian H, Redwood C, Carrier L, Dunn W
MOL BIOSYST. 2015;11(2):564-73.

Protection by the NO-Donor SNAP and BNP against Hypoxia/Reoxygenation in Rat Engineered Heart Tissue
Görbe A, Eder A, Varga Z, Pálóczi J, Hansen A, Ferdinandy P, Eschenhagen T
PLOS ONE. 2015;10(7):e0132186.

Optimizing early rule-out strategies for acute myocardial infarction: Utility of 1-hour copeptin
Hillinger P, Twerenbold R, Jaeger C, Wildi K, Reichlin T, Gimenez M, Engels U, Miró O, Boeddinghaus J, Puelacher C, Nestelberger T, Röthlisberger M, Ernst S, Rentsch K, Mueller C
CLIN CHEM. 2015;61(12):1466-1474.

Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology
Hirt M, Werner T, Indenbirken D, Alawi M, Demin P, Kunze A, Stenzig J, Starbatty J, Hansen A, Fiedler J, Thum T, Eschenhagen T
J MOL CELL CARDIOL. 2015;81:1-9.

Cardiac Arrhythmias Introduction: Action potentials and membrane currents
Jost N, Muntean D, Christ T
2015. Pathophysiology and Pharmcotherapy of Cardiovascular Dieseases . 26. Aufl. Cham Heidelberg New York Dordrecht London: Springer, .

Cardiac Arrhythmias: Introduction, Electrophysiology of the Heart, Action Potential and Membrane Currents
Jost N, Muntean D, Christ T
2015. Pathophysiology and Pharmacotherapy of Cardiovascular Disease. Jagadeesh G, Balakumar P, Maung-U K (Hrsg.). 1. Aufl. Adis, 977 - 1002.

Targeted Mybpc3 knock-out mice with cardiac hypertrophy exhibit structural mitral valve abnormalities
Judge D, Neamatalla H, Norris R, Levine R, Butcher J, Vignier N, Kang K, Nguyen Q, Bruneval P, Perier M, Messas E, Jeunemaitre X, de Vlaming A, Markwald R, Carrier L, Hagège A
J CARDIOVASC DEV DIS. 2015;2(2):48-65.

Sexual dimorphic response to exercise in hypertrophic cardiomyopathy-associated MYBPC3-targeted knock-in mice
Najafi A, Schlossarek S, van Deel E, van den Heuvel N, Güçlü A, Goebel M, Kuster D, Carrier L, van der Velden J
PFLUG ARCH EUR J PHY. 2015;467(6):1303-1317.

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts
Pecha S, Flenner F, Söhren K, Lorenz K, Eschenhagen T, Christ T
PHARMACOL RES PERSPE. 2015;3(5):e00168.

Effects of hemolysis on the diagnostic accuracy of cardiac troponin I for the diagnosis of myocardial infarction
Puelacher C, Twerenbold R, Mosimann T, Boeddinghaus J, Gimenez M, Wildi K, Jaeger C, Reichlin T, Schneider J, Honegger U, Max W, Schumacher C, Nestelberger T, Hillinger P, Grimm K, Kreutzinger P, Weidmann Z, Rentsch K, Arnold C, Osswald S, Mueller C
INT J CARDIOL. 2015;187(1):313-315.

Loss of Pace Capture on the Ablation Line During Pulmonary Vein Isolation versus "Dormant Conduction": Is Adenosine Expendable?
Schaeffer B, Willems S, Sultan A, Hoffmann B, Lüker J, Schreiber D, Akbulak R, Moser J, Kuklik P, Steven D
J CARDIOVASC ELECTR. 2015;26(10):1075-1080.

Development of phosphatase inhibitor-1 peptides acting as indirect activators of phosphatase 1
Sotoud H, Borgmeyer U, Schulze C, El-Armouche A, Eschenhagen T
N-S ARCH PHARMACOL. 2015;388(3):283-93.

Targets for therapy in sarcomeric cardiomyopathies
Tardiff J, Carrier L, Bers D, Poggesi C, Ferrantini C, Coppini R, Maier L, Ashrafian H, Huke S, van der Velden J
CARDIOVASC RES. 2015;105(4):457-70.

The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation
Thottakara T, Friedrich F, Reischmann S, Braumann S, Schlossarek S, Krämer E, Juhr D, Schlüter H, van der Velden J, Münch J, Patten M, Eschenhagen T, Moog-Lutz C, Carrier L
J MOL CELL CARDIOL. 2015;87:214-224.

Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito
Turnow K, Metzner K, Cotella D, Morales M, Schaefer M, Christ T, Ravens U, Wettwer E, Kämmerer S
BASIC RES CARDIOL. 2015;110(2):Art. 5.

Research priorities in sarcomeric cardiomyopathies
van der Velden J, Ho C, Tardiff J, Olivotto I, Knollmann B, Carrier L
CARDIOVASC RES. 2015;105(4):449-56.

Engineering Cardiovascular Regeneration
Vollert I, Eder A, Hansen A, Eschenhagen T
CURR STEM CELL REP. 2015;1(2):67-78.

Assessment of DNA synthesis in Islet-1⁺ cells in the adult murine heart
Weinberger F, Mehrkens D, Starbatty J, Nicol P, Eschenhagen T
BIOCHEM BIOPH RES CO. 2015;456(1):294-7.

MYBPC3 in hypertrophic cardiomyopathy: from mutation identification to RNA-based correction
Behrens-Gawlik V, Mearini G, Gedicke-Hornung C, Richard P, Carrier L
PFLUG ARCH EUR J PHY. 2014;466(2):215-223.

Atrial-selective antiarrhythmic activity by vernakalant fact or fiction?
Christ T
J CARDIOVASC PHARM. 2014;63(1):23-24.

Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation
Christ T, Rozmaritsa N, Engel A, Berk E, Knaut M, Metzner K, Canteras M, Ravens U, Kaumann A
P NATL ACAD SCI USA. 2014;111(30):11193-8.

Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis
Cuello F, Shankar-Hari M, Mayr U, Yin X, Marshall M, Suna G, Willeit P, Langley S, Jayawardhana T, Zeller T, Terblanche M, Shah A, Mayr M
MOL CELL PROTEOMICS. 2014;13(10):2545-57.

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury
Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bolaños J, Rakovic A, Spin J, Stubbendorff M, Ikeno F, Länger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins R, Tsao P, Schrepfer S
NATURE. 2014;509(7502):641-644.

P635Proarrhythmic drugs exert hERG-independent slowing of relaxation and irregular beating in rat engineered heart tissue
Eder A, Hansen A, Neuber C, Schaaf S, Vos M, Eschenhagen T
CARDIOVASC RES. 2014;103 Suppl 1:S115.

Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue
Eder A, Hansen A, Uebeler J, Schulze T, Neuber C, Schaaf S, Yuan L, Christ T, Vos M, Eschenhagen T
BASIC RES CARDIOL. 2014;109(6):436.

Calciumantagonisten
Eschenhagen T
2014. Arzneiverordnungsreport 2014. Schwabe U, Paffrath D (Hrsg.). 1. Aufl. Springer-Verlag Berlin, Heidelberg, 561-570.

Herztherapeutika
Eschenhagen T
2014. Arzneiverordnungsreport 2014. 1. Aufl. Springer-Verlag Berlin, Heidelberg, 681-701.

FHL2 expression and variants in hypertrophic cardiomyopathy
Friedrich F, Reischmann S, Schwalm A, Unger A, Ramanujam D, Münch J, Müller O, Hengstenberg C, Galve E, Charron P, Linke W, Engelhardt S, Patten-Hamel M, Richard P, van der Velden J, Eschenhagen T, Isnard R, Carrier L
BASIC RES CARDIOL. 2014;109(6):451.

Origin and characteristics of high Shannon entropy at the pivot of locally stable rotors: insights from computational simulation
Ganesan A, Kuklik P, Gharaviri A, Brooks A, Chapman D, Lau D, Roberts-Thomson K, Sanders P
PLOS ONE. 2014;9(11):e110662.

P425Cytoprotection by the NO-donor SNAP and BNP against ischemia/reperfusion injury in rat engineered heart tissue
Gorbe A, Eder A, Varga Z, Paloczi J, Hansen A, Ferdinandy P, Eschenhagen T
CARDIOVASC RES. 2014;103 Suppl 1:S78.

Cytoprotection by the NO-donor SNAP against ischemia/reoxygenation injury in mouse embryonic stem cell-derived cardiomyocytes
Görbe A, Varga Z, Pálóczi J, Rungarunlert S, Klincumhom N, Pirity M, Madonna R, Eschenhagen T, Dinnyés A, Csont T, Ferdinandy P
NAT BIOTECHNOL. 2014;56(3):258-264.

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation
Hirt M, Boeddinghaus J, Mitchell A, Schaaf S, Börnchen C, Müller C, Schulz H, Hubner N, Stenzig J, Stoehr A, Neuber C, Eder A, Luther P, Hansen A, Eschenhagen T
J MOL CELL CARDIOL. 2014;74C:151-161.

Cardiac Tissue Engineering State of the Art
Hirt M, Hansen A, Eschenhagen T
CIRC RES. 2014;114(2):354-367.

The continuum of personalized cardiovascular medicine: a position paper of the European Society of Cardiology
Kirchhof P, Sipido K, Cowie M, Eschenhagen T, Fox K, Katus H, Schroeder S, Schunkert H, Priori S
EUR HEART J. 2014;35(46):3250-3257.

Heart failure-specific changes in protein kinase signalling
Lorenz K, Stathopoulou K, Schmid E, Eder P, Cuello F
PFLUG ARCH EUR J PHY. 2014;466(6):1151-1162.

Myelin basic protein cleaves cell adhesion molecule l1 and promotes neuritogenesis and cell survival.
Lutz D, Loers G, Kleene R, Oezen I, Kataria H, Katagihallimath N, Braren I, Harauz G, Schachner M
J BIOL CHEM. 2014;289(19):13503-13518.

Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice
Mearini G, Stimpel D, Geertz B, Weinberger F, Krämer E, Schlossarek S, Mourot-Filiatre J, Stoehr A, Dutsch A, Wijnker P, Braren I, Katus H, Müller O, Voit T, Eschenhagen T, Carrier L
NAT COMMUN. 2014;5:5515.

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation
Mesirca P, Alig J, Torrente A, Müller J, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, Nargeot J, Wickman K, Isbrandt D, Mangoni M
NAT COMMUN. 2014;5:4664.

GeSRU-Jahresüberblick 2015: Weiterbilden, Netzwerken und Karriereplanen
Meyer C, Beyer B, Arnold H, Borgmann H, Salem J
UROLOGE. 2014;53(12):1817-9.

Paradoxical effects on force generation after efficient β1-adrenoceptor knockdown in reconstituted heart tissue
Neuber C, Müller O, Hansen F, Eder A, Witten A, Rühle F, Stoll M, Katus H, Eschenhagen T, El-Armouche A
J PHARMACOL EXP THER. 2014;349(1):39-46.

Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes
Neuber C, Uebeler J, Schulze T, Sotoud H, El-Armouche A, Eschenhagen T
PLOS ONE. 2014;9(6):e98893.

P368Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes
Neuber C, Uebeler J, Schulze T, Sotoud H, El-Armouche A, Eschenhagen T
CARDIOVASC RES. 2014;103 Suppl 1:S67.

Prostaglandin E2 does not attenuate adrenergic-induced cardiac contractile response
Pecha S, Mudersbach E, Söhren K, Hakmi S, Reichenspurner H, Eschenhagen T, Christ T
N-S ARCH PHARMACOL. 2014;387(10):963-968.

Attenuated response of L-type calcium current to nitric oxide in atrial fibrillation
Rozmaritsa N, Christ T, Van Wagoner D, Haase H, Stasch J, Matschke K, Ravens U
CARDIOVASC RES. 2014;101(3):533-542.

Generation of Strip-Format Fibrin-Based Engineered Heart Tissue (EHT)
Schaaf S, Eder A, Vollert I, Stöhr A, Hansen A, Eschenhagen T
2014. Cardiac Tissue Engineering. Radisic M, Black III L (Hrsg.). 1. Aufl. New York: Springer Science+Business Media New York, 121-129.

Ubiquitin-proteasome system and hereditary cardiomyopathies
Schlossarek S, Frey N, Carrier L
J MOL CELL CARDIOL. 2014;71:25-31.

Proteasome inhibition slightly improves cardiac function in mice with hypertrophic cardiomyopathy
Schlossarek S, Singh S, Geertz B, Schulz H, Reischmann S, Hübner N, Carrier L
FRONT PHYSIOL. 2014;5:484.

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria
Skibsbye L, Poulet C, Diness J, Bentzen B, Yuan L, Kappert U, Matschke K, Wettwer E, Ravens U, Grunnet M, Christ T, Jespersen T
CARDIOVASC RES. 2014;103(1):156-167.

Four-and-a-half LIM domains proteins are novel regulators of the protein kinase D pathway in cardiac myocytes
Stathopoulou K, Cuello F, Candasamy A, Kemp E, Ehler E, Haworth R, Avkiran M
BIOCHEM J. 2014;457(3):451-461.

Automated analysis of contractile force and Ca2+ transients in engineered heart tissue
Stoehr A, Neuber C, Baldauf C, Vollert I, Friedrich F, Flenner F, Carrier L, Eder A, Schaaf S, Hirt M, Aksehirlioglu B, Tong C, Moretti A, Eschenhagen T, Hansen A
AM J PHYSIOL-HEART C. 2014;306(9):H1353-H1363.

Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes
Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, Inohara T, Arimura T, Makino S, Kimura K, Kimura A, Furukawa T, Carrier L, Node K, Fukuda K
J AM HEART ASSOC. 2014;3(6):e001263.

Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction
Unsöld B, Kaul A, Sbroggiò M, Schubert C, Regitz-Zagrosek V, Brancaccio M, Damilano F, Hirsch E, Van Bilsen M, Munts C, Sipido K, Bito V, Detre E, Wagner N, Schäfer K, Seidler T, Vogt J, Neef S, Bleckmann A, Maier L, Balligand J, Bouzin C, Ventura-Clapier R, Garnier A, Eschenhagen T, El-Armouche A, Knöll R, Tarone G, Hasenfuß G
CARDIOVASC RES. 2014;101(1):97-107.

AT1 blockade abolishes left ventricular hypertrophy in heterozygous cMyBP-C null mice: role of FHL1
Vignier N, Le Corvoisier P, Blard C, Sambin L, Azibani F, Schlossarek S, Delcayre C, Carrier L, Hittinger L, Su J
FUND CLIN PHARMACOL. 2014;28(3):249-256.

P778Physiological and pharmacological characterization of human engineered heart tissue
Vollert I, Schaaf S, Neuber C, Letuffe-Breniere D, Breckwoldt K, Shibamiya A, Stimpel D, Eder A, Eschenhagen T, Hansen A
CARDIOVASC RES. 2014;103 Suppl 1:S143.

In vitro perfusion of engineered heart tissue through endothelialized channels
Vollert I, Seiffert M, Bachmair J, Sander M, Eder A, Conradi L, Vogelsang A, Schulze T, Uebeler J, Holnthoner W, Redl H, Reichenspurner H, Hansen A, Eschenhagen T
TISSUE ENG PT A. 2014;20(3-4):854-63.

Myocardial tissue Engineering: in vitro models
Vunjak Novakovic G, Eschenhagen T, Mummery C
CSH PERSPECT MED. 2014;4(3):.

Hamburger Pharmakologie-Repetitorium: Eine Übersicht klinisch relevanter arzneitherapeutischer Fakten
Wuttke A, Eschenhagen T, Hirt M, Hansen A, Stenzig J, Weinberger F, Werner U, Friedrich F, Schwedhelm E, Lüneburg N, Anderssohn M
2014. Hamburger Pharmakologie-Repetitorium. Wuttke A, Eschenhagen T (Hrsg.). 3. Aufl. Hamburg: Eigenverlag, .

Extracellular matrix secretion by cardiac fibroblasts Role of microRNA-29b and microRNA-30c
Abonnenc M, Nabeebaccus A, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley S, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann W, Shah A, Zampetaki A, Mayr M
CIRC RES. 2013;113(10):1138-47.

Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity
Cattin M, Bertrand A, Schlossarek S, Le Bihan M, Skov Jensen S, Neuber C, Crocini C, Maron S, Lainé J, Mougenot N, Varnous S, Fromes Y, Hansen A, Eschenhagen T, Decostre V, Carrier L, Bonne G
HUM MOL GENET. 2013;22(15):3152-64.

Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue
Crocini C, Arimura T, Reischmann S, Eder A, Braren I, Hansen A, Eschenhagen T, Kimura A, Carrier L
BASIC RES CARDIOL. 2013;108(3):349.

Parthenogenetic stem cells for tissue-engineered heart repair
Didié M, Christalla P, Rubart M, Muppala V, Döker S, Unsöld B, El-Armouche A, Rau T, Eschenhagen T, Schwoerer A, Ehmke H, Schumacher U, Fuchs S, Lange C, Becker A, Tao W, Scherschel J, Soonpaa M, Yang T, Lin Q, Zenke M, Han D, Schöler H, Rudolph C, Steinemann D, Schlegelberger B, Kattman S, Witty A, Keller G, Field L, Zimmermann W
J CLIN INVEST. 2013;123(3):1285-98.

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure
Dirkx E, Gladka M, Philippen L, Armand A, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva G, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders P, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins P, De Windt L
NAT CELL BIOL. 2013;15(11):1282-93.

Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects
Donzelli S, Fischer G, King B, Niemann C, DuMond J, Heeren J, Wieboldt H, Baldus S, Gerloff C, Eschenhagen T, Carrier L, Böger R, Espey M
J PHARMACOL EXP THER. 2013;344(2):339-47.

A frequent gene polymorphism affecting the heart-rate response to carvedilol
Eschenhagen T
PHARMACOGENOMICS. 2013;14(2):115-8.

Calciumantagonisten
Eschenhagen T
2013. Arzneiverordnungsreport 2013. Schwabe U, Paffrath D (Hrsg.). Springer-Verlag Berlin, Heidelberg, 503-512.

Herztherapeutika
Eschenhagen T
2013. Arzneiverordnungsreport 2013. Springer-Verlag Berlin, Heidelberg, 621-639.

Mit Stammzell-Modellen Herzkrankheiten besser verstehen
Eschenhagen T
DEUT MED WOCHENSCHR. 2013;138(46):2381-2.

New tissue for failing hearts
Eschenhagen T
EUR J HEART FAIL. 2013;15(1):1-2.

PDE4 in the human heart - major player or little helper?
Eschenhagen T
BRIT J PHARMACOL. 2013;169(3):524-7.

Pharmakologie des kardiovaskulären Systems - das Herz
Eschenhagen T
2013. Allgemeine und spezielle Pharmakologie und Toxikologie . Aktories K, Förstermann U, Hofmann F, Starke K (Hrsg.). 11. Aufl. München: Urban & Fischer, 381-435.

Personalisierte Therapie in der Kardiologie. Biomarker, Pharmakogenetik und Therapie monogener Erkrankungen
Eschenhagen T, Blankenberg S
INTERNIST. 2013;54(2):147-8, 150-2, 154.

Medikamente zur Therapie der Herzinsuffizienz: Wie wirkt Relaxin?
Eschenhagen T, Weinberger F
Cardio News. 2013;(5):14-15.

Wie wirkt L-Arginin?
Eschenhagen T, Weinberger F
Herz Heute. 2013;(3):44-45.

Tissue-Engineered Cardiovascular Products
Eschenhagen T, Zimmermann W
2013. Principles of Tissue Engineering, 4th Edition . Lanza R, Langer R, Vacanti J (Hrsg.). 4. Aufl. London: Academic Press, 1745–1764.

Wie wichtig sind Medikamente?
Eschenhagen T, Zimmermann W
2013. Das schwache Herz. Frankfurt a. M.: Deutsche Herzstiftung e.V., 47-54.

Herz-Kreislaufsystem
Eschenhagen T, Zolk O
2013. Toxikologie . Marquardt H, Schäfer S, Barth H (Hrsg.). 3. Aufl. Stuttgart: Wissenschaftliche Verlagsgesellschaft, 569-592.

Functional MicroRNA Library Screening Identifies the HypoxaMiR MiR-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization
Fiedler J, Stöhr A, Gupta S, Hartmann D, Holzmann A, Just A, Hansen A, Hilfiker-Kleiner D, Eschenhagen T, Thum T
ANTIOXID REDOX SIGN. 2013.

A novel genetic variant in the transcription factor Islet-1 exerts gain of function on myocyte enhancer factor 2C promoter activity
Friedrich F, Dilanian G, Khattar P, Juhr D, Gueneau L, Charron P, Fressart V, Vilquin J, Isnard R, Gouya L, Richard P, Hammoudi N, Komajda M, Bonne G, Eschenhagen T, Dubourg O, Villard E, Carrier L
EUR J HEART FAIL. 2013;15(3):267-76.

B-scan ultrasonographic monitoring of orthotopic xenografted plexiform neurofibroma in mice
Gleiss J, Demestre M, Spyra M, Eschenhagen T, Hagel C, Mautner V, Kluwe L, Friedrich R
IN VIVO. 2013;27(6):723-7.

The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation
Guhr S, Sachs M, Wegner A, Becker J, Meyer T, Kietzmann L, Schlossarek S, Carrier L, Balabanov M, Jat P, Stahl R, Meyer-Schwesinger C
KIDNEY INT. 2013;84(3):532-44.

Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia
Harder L, Eschenburg G, Zech A, Kriebitzsch N, Otto B, Streichert T, Behlich A, Dierck K, Klingler B, Hansen A, Stanulla M, Zimmermann M, Kremmer E, Stocking C, Horstmann M
J EXP MED. 2013;210(11):2289-304.

Vernakalant
Hirt M, Eschenhagen T
Internistische Praxis. 2013;(53):.

Herzprobleme unter Neuroleptika
Hirt M, Oetjen E
Herz Heute. 2013.

Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase
Holland R, Paulisch R, Cao Z, Keefer L, Saavedra J, Donzelli S
NITRIC OXIDE-BIOL CH. 2013;35:131-6.

Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice
Hornung C, Behrens V, Reischmann S, Geertz B, Stimpel D, Weinberger F, Schlossarek S, Précigout G, Braren I, Eschenhagen T, Mearini G, Lorain S, Voit T, Dreyfus P, Garcia L, Carrier L
EMBO MOL MED. 2013;5(7):1060-77.

BSE-associated prion-amyloid cardiomyopathy in primates
Krasemann S, Mearini G, Krämer E, Wagenführ K, Schulz-Schaeffer W, Neumann M, Bodemer W, Kaup F, Beekes M, Carrier L, Aguzzi A, Glatzel M
EMERG INFECT DIS. 2013;19(6):985-8.

GSK3β phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication
Kuster D, Sequeira V, Najafi A, Boontje N, Wijnker P, Witjas-Paalberends E, Marston S, Dos Remedios C, Carrier L, Demmers J, Redwood C, Sadayappan S, van der Velden J
CIRC RES. 2013;112(4):633-9.

Repair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy
Mearini G, Stimpel D, Krämer E, Geertz B, Braren I, Hornung C, Précigout G, Müller O, Katus H, Eschenhagen T, Voit T, Garcia L, Lorain S, Carrier L
MOL THER-NUCL ACIDS. 2013;2:e102.

Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier L, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann W, Nikolaev V, Vandecasteele G, Fischmeister R, El-Armouche A
J AM COLL CARDIOL. 2013;62(17):1596-606.

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Nebel M, Schwoerer A, Warszta D, Siebrands C, Limbrock A, Swarbrick J, Fliegert R, Weber K, Bruhn S, Hohenegger M, Geisler A, Herich L, Schlegel S, Carrier L, Eschenhagen T, Potter B, Ehmke H, Guse A
J BIOL CHEM. 2013;288(22):16017-30.

Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading
Schwoerer A, Neef S, Broichhausen I, Jacubeit J, Tiburcy M, Wagner M, Biermann D, Didié M, Vettel C, Maier L, Zimmermann W, Carrier L, Eschenhagen T, Volk T, El-Armouche A, Ehmke H
PFLUG ARCH EUR J PHY. 2013;465(12):1763-73.

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations
Sequeira V, Wijnker P, Nijenkamp L, Kuster D, Najafi A, Witjas-Paalberends E, Regan J, Boontje N, Ten Cate F, Germans T, Carrier L, Sadayappan S, van Slegtenhorst M, Zaremba R, Foster D, Murphy A, Poggesi C, Dos Remedios C, Stienen G, Ho C, Michels M, van der Velden J
CIRC RES. 2013;112(11):1491-505.

Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approaches
Sotoud H, Gribbon P, Ellinger B, Reinshagen J, Boknik P, Kattner L, El-Armouche A, Eschenhagen T
J BIOMOL SCREEN. 2013;18(8):899-909.

Warnung vor Diclofenac: Was nun?
Stenzig J, Oetjen E
Herz Heute. 2013;33(4):18-21.

Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice
Stöhr A, Friedrich F, Flenner F, Geertz B, Eder A, Schaaf S, Hirt M, Uebeler J, Schlossarek S, Carrier L, Hansen A, Eschenhagen T
J MOL CELL CARDIOL. 2013;63:189-98.

Distinctive serum miRNA profile in mouse models of striated muscular pathologies
Vignier N, Amor F, Fogel P, Duvallet A, Poupiot J, Charrier S, Arock M, Montus M, Nelson I, Richard I, Carrier L, Servais L, Voit T, Bonne G, Israeli D
PLOS ONE. 2013;8(2):e55281.

Aldosterone inhibits antifibrotic factors in mouse hypertensive heart
Azibani F, Benard L, Schlossarek S, Merval R, Tournoux F, Fazal L, Polidano E, Launay J, Carrier L, Chatziantoniou C, Samuel J, Delcayre C
HYPERTENSION. 2012;59(6):1179-1187.

Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice
Azibani F, Devaux Y, Coutance G, Schlossarek S, Polidano E, Fazal L, Merval R, Carrier L, Solal A, Chatziantoniou C, Launay J, Samuel J, Delcayre C
PLOS ONE. 2012;7(5):e38197.

cMyBP-C as a promiscuous substrate: phosphorylation by non-PKA kinases and its potential significance.
Bardswell S, Cuello F, Kentish J, Avkiran M
J MUSCLE RES CELL M. 2012;33(1):53-60.

DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.
Bertrand A, Renou L, Papadopoulos A, Beuvin M, Lacène E, Massart C, Ottolenghi C, Decostre V, Maron S, Schlossarek S, Cattin M, Carrier L, Malissen M, Arimura T, Bonne G
HUM MOL GENET. 2012;21(5):1037-1048.

Impact of AT2 receptor deficiency on postnatal cardiovascular development.
Biermann D, Heilmann A, Didié M, Schlossarek S, Wahab A, Grimm M, Römer M, Reichenspurner H, Sultan K, Steenpass A, Ergün S, Donzelli S, Carrier L, Ehmke H, Zimmermann W, Hein L, Böger R, Benndorf R
PLOS ONE. 2012;7(10):47916.

Complex interactions between human myoblasts and the surrounding 3D fibrin-based matrix.
Chiron S, Tomczak C, Duperray A, Lainé J, Bonne G, Eder A, Hansen A, Eschenhagen T, Verdier C, Coirault C
PLOS ONE. 2012;7(4):36173.

Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function.
Dijk v, Sabine J, Paalberends E, Najafi A, Michels M, Carrier L, Carrier L, Boontje N, Kuster D, van Slegtenhorst M, Dooijes D, Cris D, Cate T, Folkert J, Stienen G, van der Velden J
CIRC-HEART FAIL. 2012;5(1):36-46.

Protein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser315.
Dirkx E, Cazorla O, Schwenk R, Lorenzen-Schmidt I, Sadayappan S, Johan V, Carrier L, Eys v, Guillaume J, Glatz J, Luiken J
AM J PHYSIOL-HEART C. 2012;303(3):323-331.

Multi-Well Engineered Heart Tissue for Drug Screening and Predictive Toxicology
Eder A, Hansen A, Eschenhagen T
2012. Toxicity and Drug Testing. InTech: 71-90.

Calciumantagonisten
Eschenhagen T
2012. Arzneiverordnungs-Report 2012. Springer Berlin Heidelberg: 515-524.

Herztherapeutika
Eschenhagen T
2012. Arzneiverordnungs-Report 2012. Springer Berlin Heidelberg: 633-652.

Physiological aspects of cardiac tissue engineering.
Eschenhagen T, Eder A, Vollert I, Hansen A
AM J PHYSIOL-HEART C. 2012;303(2):133-143.

Engineered Heart Tissue
Eschenhagen T, Zimmermann W
2012. Heart Regeneration: Stem Cells and Beyond. World Scientific Publishing Company: 299-326.

Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice.
Fraysse B, Weinberger F, Bardswell S, Cuello F, Vignier N, Geertz B, Starbatty J, Krämer E, Coirault C, Eschenhagen T, Kentish J, Avkiran M, Carrier L
J MOL CELL CARDIOL. 2012;52(6):1299-1307.

Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data.
Fredersdorf S, Thumann C, Zimmermann W, Vetter R, Graf T, Luchner A, Riegger G, Schunkert H, Eschenhagen T, Weil J
CARDIOVASC DIABETOL. 2012;11:57.

Genetics of hypertrophic and dilated cardiomyopathy.
Friedrich F, Carrier L
CURR PHARM BIOTECHNO. 2012;13(13):2467-2476.

Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy.
Friedrich F, Wilding B, Reischmann S, Crocini C, Lang P, Charron P, Müller O, McGrath M, Vollert I, Hansen A, Linke W, Hengstenberg C, Bonne G, Morner S, Wichter T, Madeira H, Arbustini E, Eschenhagen T, Mitchell C, Isnard R, Carrier L
HUM MOL GENET. 2012;21(14):3237-3254.

Neurohormonal regulation of cardiac histone deacetylase 5 nuclear localization by phosphorylation-dependent and phosphorylation-independent mechanisms.
Haworth R, Stathopoulou K, Candasamy A, Avkiran M
CIRC RES. 2012;110(12):1585-1595.

Increased afterload induces pathological cardiac hypertrophy: a new in vitro model.
Hirt M, Sörensen N, Bartholdt L, Boeddinghaus J, Schaaf S, Eder A, Vollert I, Stöhr A, Schulze T, Witten A, Stoll M, Hansen A, Eschenhagen T
BASIC RES CARDIOL. 2012;107(6):307.

A novel in vivo model for the study of human breast cancer metastasis using primary breast tumor-initiating cells from patient biopsies.
Marsden C, Wright M, Carrier L, Moroz K, Pochampally R, Rowan B
BMC CANCER. 2012;12:10.

How do MYBPC3 mutations cause hypertrophic cardiomyopathy?
Marston S, Copeland O, Gehmlich K, Schlossarek S, Carrier L
J MUSCLE RES CELL M. 2012;33(1):75-80.

The German Centre for Cardiovascular Research.
Prendergast B, Coope L, Crijns H, Falkenstein E, Fölsch U, Halvorsen S, Janssens S, Jokinen E, Kroemer H, Lücke A, Murer H, Nagel E, Neyses L, Perk J, Probst-Hensch N, Rietschel E, Rütten H, Steingen C, Tedgui A, van Gilst W, Eschenhagen T, Kristensen S
EUR HEART J. 2012;33(9):1033-1036.

Impact of the β1-adrenoceptor Arg389Gly polymorphism on heart-rate responses to bisoprolol and carvedilol in heart-failure patients.
Rau T, Düngen H, Edelmann F, Waagstein F, Lainščak M, Dimković S, Apostolović S, Nešković A, Haverkamp W, Gelbrich G, Eschenhagen T
CLIN PHARMACOL THER. 2012;92(1):21-28.

Myeloperoxidase deficiency preserves vasomotor function in humans.
Rudolph T, Wipper S, Reiter B, Rudolph V, Coym A, Detter C, Lau D, Klinke A, Friedrichs K, Rau T, Pekarova M, Russ D, Knöll K, Stubendorff M, Schroeder B, Wegscheider K, Andresen H, Schwedhelm E, Böger R, Ehmke H, Baldus S
EUR HEART J. 2012;33(13):1625-1634.

Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy.
Schlossarek S, Englmann D, Sultan K, Sauer M, Eschenhagen T, Carrier L
BASIC RES CARDIOL. 2012;107(1):235.

Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice
Schlossarek S, Schürmann F, Geertz B, Mearini G, Eschenhagen T, Carrier L
J MUSCLE RES CELL M. 2012;33(1):5-15.

Succinate reverses in-vitro platelet inhibition by acetylsalicylic acid and P2Y receptor antagonists.
Spath B, Hansen A, Bokemeyer C, Langer F
PLATELETS. 2012;23(1):60-68.

Progesterone receptor variants associated with the PROGINS haplotype exhibit functional properties similar to those of wild-type progesterone receptor.
Stenzig J, Schweikert A, Piasecki A, Höppner G, Eschenhagen T, Rau T
PHARMACOGENET GENOM. 2012;22(8):629-641.

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.
Ucar A, Gupta S, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, Remke J, Caprio M, Jentzsch C, Engelhardt S, Geisendorf S, Glas C, Hofmann T, Nessling M, Richter K, Schiffer M, Carrier L, Napp L, Bauersachs J, Chowdhury K, Thum T
NAT COMMUN. 2012;3:1078.

Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.
Weinberger F, Mehrkens D, Friedrich F, Stubendorff M, Hua X, Müller J, Schrepfer S, Evans S, Carrier L, Eschenhagen T
CIRC RES. 2012;110(10):1303-1310.

Oral antiplatelet agents in ACS: from pharmacology to clinical differences.
Agewall S, Badimon L, Drouet L, Eschenhagen T, Husted S, Simon T, Steg G
FUND CLIN PHARMACOL. 2011;25(5):564-571.

Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium
Boontje N, Merkus D, Zaremba R, Versteilen A, Waard d, Mearini G, Mearini G, Carrier L, Vincent J, Carrier L, Walker L, Niessen H, Dobrev D, Stienen G, Duncker D, van der Velden J
J MOL CELL CARDIOL. 2011;50(3):487-499.

Hypertrophic cardiomyopathy
Christiaans I, Carrier L
2011. Clinical Cardiogenetics. Springer Berlin Heidelberg: 47-62.

Bioluminescence imaging for assessment of immune responses following implantation of engineered heart tissue (EHT).
Conradi L, Pahrmann C, Schmidt S, Deuse T, Hansen A, Eder A, Reichenspurner H, Robbins R, Eschenhagen T, Schrepfer S
JOVE-J VIS EXP. 2011;52:2605.

Titration to target dose of bisoprolol vs. carvedilol in elderly patients with heart failure: the CIBIS-ELD trial.
Düngen H, Apostolovic S, Inkrot S, Tahirovic E, Töpper A, Mehrhof F, Prettin C, Putnikovic B, Neskovic A, Krotin M, Sakac D, Lainscak M, Edelmann F, Wachter R, Rau T, Eschenhagen T, Doehner W, Anker S, Waagstein F, Herrmann-Lingen C, Gelbrich G, Dietz R, Investigators C, Failure P
EUR J HEART FAIL. 2011;13(6):670-680.

Follistatin-like 1 in chronic systolic heart failure: a marker of left ventricular remodeling.
El-Armouche A, Ouchi N, Tanaka K, Doros G, Wittköpper K, Schulze T, Eschenhagen T, Walsh K, Sam F
CIRC-HEART FAIL. 2011;4(5):621-627.

The beat goes on: human heart muscle from pluripotent stem cells.
Eschenhagen T
CIRC RES. 2011;109(1):2-4.

Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.
Eschenhagen T, Force T, Ewer M, Keulenaer d, Gilles W, Suter T, Anker S, Avkiran M, de Azambuja E, Balligand J, Brutsaert D, Hansen A, Hansen A, Heymans S, Hill J, Hirsch E, Hilfiker-Kleiner D, Janssens S, de Jong S, Neubauer G, Pieske B, Ponikowski P, Pirmohamed M, Rauchhaus M, Sawyer D, Sugden P, Wojta J, Zannad F, Shah A
EUR J HEART FAIL. 2011;13(1):1-10.

Distinction Between Two Populations of Islet-1-Positive Cells in Hearts of Different Murine Strains.
Khattar P, Friedrich F, Bonne G, Carrier L, Eschenhagen T, Evans S, Schwartz K, Fiszman M, Vilquin J
STEM CELLS DEV. 2011;20(6):1043-1052.

Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.
Kornfeld J, Meder S, Wohlberg M, Friedrich R, Rau T, Riethdorf L, Löning T, Pantel K, Riethdorf S
BRIT J CANCER. 2011;104(1):138-145.

Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy.
Meyer-Schwesinger C, Meyer T, Sievert H, Hoxha E, Sachs M, Klupp E, Münster S, Balabanov S, Carrier L, Helmchen U, Thaiss F, Stahl R
AM J PATHOL. 2011;178(5):2044-2057.

The effect of mesenchymal stem cell osteoblastic differentiation on the mechanical properties of engineered bone-like tissue.
Naito H, Dohi Y, Zimmermann W, Tojo T, Takasawa S, Eschenhagen T, Taniguchi S
TISSUE ENG PT A. 2011;17(17-18):2321-2329.

Engineering bioartificial tracheal tissue using hybrid fibroblast-mesenchymal stem cell cultures in collagen hydrogels.
Naito H, Tojo T, Kimura M, Dohi Y, Zimmermann W, Eschenhagen T, Taniguchi S
INTERACT CARDIOV TH. 2011;12(2):156-161.

Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.
Schaaf S, Shibamiya A, Mewe M, Eder A, Stöhr A, Hirt M, Rau T, Zimmermann W, Conradi L, Eschenhagen T, Hansen A
PLOS ONE. 2011;6(10):26397.

The ubiquitin-proteasome system in cardiomyopathies.
Schlossarek S, Carrier L
CURR OPIN CARDIOL. 2011;26(3):190-195.

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities.
Schlossarek S, Mearini G, Carrier L
J MOL CELL CARDIOL. 2011;50(4):613-620.

Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
Tiburcy M, Didié M, Boy O, Christalla P, Döker S, Naito H, Karikkineth B, El-Armouche A, Grimm M, Nose M, Eschenhagen T, Zieseniss A, Katschinksi D, Hamdani N, Linke W, Yin X, Mayr M, Zimmermann W
CIRC RES. 2011;109(10):1105-1114.

Phosphatase-1-inhibitor-1 in physiological and pathological {beta}-adrenoceptor signaling.
Wittköpper K, Dobrev D, Eschenhagen T, El-Armouche A
CARDIOVASC RES. 2011;91(3):392-401.

Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.
Belus A, Nicoletta P, Ferrantini C, Tesi C, Cazorla O, Toniolo L, Drost M, Mearini G, Carrier L, Rossi A, Mugelli A, Cerbai E, van der Velden J, Poggesi C
CIRC RES. 2010;107(1):144-152.

Too much of a good thing is bad: proteasome inhibition induces stressed hearts to fail.
Carrier L
CARDIOVASC RES. 2010;88(3):389-390.

Stoppt Bremse des Proteinabbaus die Hypertrophie?
Carrier L, Schlossarek S
Cardio News. 2010;13(3):22-23.

The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy.
Carrier L, Schlossarek S, Willis M, Eschenhagen T
CARDIOVASC RES. 2010;85(2):330-338.

Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.
El-Armouche A, Schwoerer A, Neuber C, Emmons J, Biermann D, Christalla T, Grundhoff A, Eschenhagen T, Zimmermann W, Ehmke H
PLOS ONE. 2010;5(12):14263.

The new HNO donor, 1-nitrosocyclohexyl acetate, increases contractile force in normal and β-adrenergically desensitized ventricular myocytes
El-Armouche A, Wahab A, Wittköpper K, Schulze T, Böttcher F, Pohlmann L, King S, DuMond J, Gerloff C, Böger R, Eschenhagen T, Carrier L, Donzelli S
BIOCHEM BIOPH RES CO. 2010;402(2):340-344.

Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure?
Eschenhagen T
J CLIN INVEST. 2010;120(12):4197-4203.

Development of a drug screening platform based on engineered heart tissue.
Hansen A, Eder A, Bönstrup M, Flato M, Mewe M, Schaaf S, Aksehirlioglu B, Schwoerer A, Uebeler J, Eschenhagen T
CIRC RES. 2010;107(1):35-44.

Sorafenib
Hansen A, Eschenhagen T
DEUT MED WOCHENSCHR. 2010;135(37):1819-1822.

Vernakalant: Ein neues Antiarrhythmikum zur Akutbehandlung von Vorhofflimmern
Hirt M, Eschenhagen T
DEUT MED WOCHENSCHR. 2010;135(19):971-6.

[Vernakalant: a novel antiarrhythmic drug for the rapid conversion of atrial fibrillation to sinus rhythm].
Hirt M, Eschenhagen T
DEUT MED WOCHENSCHR. 2010;135(19):971-976.

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.
Martins D, Paula A, Salic K, Gladka M, Armand A, Leptidis S, Hansen A, Hansen A, Roo C, Christina J, Bierhuizen M, van der Nagel R, van Kuik J, de Weger R, de Bruin A, Eschenhagen T, Arbones M, Eschenhagen T, Windt D, Leon J
NAT CELL BIOL. 2010;12(12):1220-1227.

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Mearini G, Hornung C, Schlossarek S, Witt C, Krämer E, Cao P, Gomes M, Lecker S, Labeit S, Willis M, Eschenhagen T, Carrier L
CARDIOVASC RES. 2010;85(2):357-366.

Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial.
Riethdorf S, Müller V, Zhang L, Rau T, Loibl S, Komor M, Roller M, Huober J, Fehm T, Schrader I, Hilfrich J, Holms F, Tesch H, Eidtmann H, Untch M, von Minckwitz G, Pantel K
CLIN CANCER RES. 2010;16(9):2634-2645.

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Rudolph V, Andrié R, Rudolph T, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer A, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner E, Szöcs K, Schrickel J, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann W, Meinertz T, Böger R, Reichenspurner H, Freeman B, Eschenhagen T, Ehmke H, Hazen S, Willems S, Baldus S
NAT MED. 2010;16(4):470-474.

Regional diastolic and systolic function by strain rate imaging for the detection of intramural viability during dobutamine stress echocardiography in a porcine model of myocardial infarction.
Schneider C, Jaquet K, Geidel S, Malisius R, Boczor S, Rau T, Zienkiewicz T, Hennig D, Kuck K, Krause K
ECHOCARDIOGR-J CARD. 2010;27(5):552-562.

The angiotensin II type 2 receptor in renal disease.
Wenzel U, Krebs C, Benndorf R
J RENIN-ANGIO-ALDO S. 2010;11(1):37-41.

Gender is an important determinant of the disposition of the loop diuretic torasemide.
Werner U, Werner D, Heinbüchner S, Graf B, Ince H, Kische S, Thürmann P, König J, Fromm M, Zolk O
J CLIN PHARMACOL. 2010;50(2):160-168.

Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing.
Will R, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger T, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus H, Frey N
CIRC RES. 2010;107(10):1253-1264.

Phosphatase-1-inhibitor-1: amplifier or attenuator of catecholaminergic stress?
Wittköpper K, Eschenhagen T, El-Armouche A
BASIC RES CARDIOL. 2010;105(5):569-571.

Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging.
Wittköpper K, Fabritz L, Neef S, Ort K, Grefe C, Unsöld B, Kirchhof P, Maier L, Hasenfuss G, Dobrev D, Eschenhagen T, El-Armouche A
J CLIN INVEST. 2010;120(2):617-626.

Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.
Aucella F, Maas R, Vigilante M, Tripepi G, Schwedhelm E, Margaglione M, Gesualdo L, Boeger R, Zoccali C
ATHEROSCLEROSIS. 2009.

Predicting recurrence of vasovagal syncope: a simple risk score for the clinical routine.
Aydin M, Maas R, Mortensen K, Steinig T, Klemm H, Risius T, Meinertz T, Willems S, Morillo C, Ventura R
J CARDIOVASC ELECTR. 2009;20(4):416-421.

Expression of heat shock proteins in tissues from young pigs exposed to transport stress.
Bao E, Sultan K, Bernhard N, Hartung J
Dtsch Tierarztl Wochenschr. 2009;116(9):321-325.

Analgesic and antiinflammatory activity of Morinda citrifolia L. (Noni) fruit.
Basar S, Uhlenhut K, Högger P, Schöne F, Westendorf J
PHYTOTHER RES. 2009.

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
Benndorf R, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz O, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl R, Böger R, Wenzel U
KIDNEY INT. 2009;75(10):1039-1049.

Renal resistance index in renal allograft recipients: a role for ADMA.
Bergmann I, Böger R, Marti E, Frey F, Schwedhelm E, Eisenberger U
AM J KIDNEY DIS. 2009.

Correlation of biomarkers of endothelium dysfunction and matrix remodeling in patients with systemic sclerosis.
Blaise S, Maas R, Trocme C, Kom G, Roustit M, Carpentier P, Cracowski J
J RHEUMATOL. 2009;36(5):984-988.

Asymmetric dimethylarginine: Understanding the physiology, genetics, and clinical relevance of this novel biomarker Proceedings of the 4th International Symposium on ADMA.
Böger R
PHARMACOL RES. 2009;60(6):447.

Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality-An update on patient populations with a wide range of cardiovascular risk.
Böger R, Maas R, Schulze F, Schwedhelm E
PHARMACOL RES. 2009;60(6):481-487.

Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community.
Böger R, Sullivan Lisa M, Schwedhelm E, Wang T, Maas R, Benjamin E, Schulze F, Xanthakis V, Benndorf R, Vasan R
CIRCULATION. 2009;119(12):1592-1600.

Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis.
Broedbaek K, Poulsen H, Weimann A, Kom G, Schwedhelm E, Nielsen P, Böger R
FREE RADICAL BIO MED. 2009;47(8):1230-1233.

[Cyclooxygenase inhibitors: adverse drug reactions are unavoidable, but only a few are (acutely) dangerous]
Brune K, Renner B, Maas R
DEUT MED WOCHENSCHR. 2009;134(36):1771-1773.

HNO exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Choe C, Lewerenz J, Fischer G, Uliasz T, Espey M, Hummel F, Bruce King S, Schwedhelm E, Böger R, Gerloff C, Hewett S, Magnus T, Donzelli S
J NEUROCHEM. 2009.

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity
Choe C, Lewerenz J, Fischer G, Uliasz T, Espey M, Hummel F, King S, Schwedhelm E, Böger R, Gerloff C, Hewett S, Magnus T, Donzelli S
J NEUROCHEM. 2009;110(6):1766-73.

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.
Deuse T, Peter C, Fedak P, Doyle T, Reichenspurner H, Zimmermann W, Eschenhagen T, Stein W, Wu J, Robbins R, Schrepfer S
CIRCULATION. 2009;120(11):247-254.

Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction.
Dijk v, Sabine J, Dooijes D, Cris D, Michels M, Lamers J, Schlossarek S, Schlossarek S, Carrier L, Cate T, Folkert J, Stienen G, van der Velden J
CIRCULATION. 2009;119(11):1473-1483.

Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling.
Duncker D, Boontje N, Merkus D, Versteilen A, Krysiak J, Mearini G, El-Armouche A, Beer d, Vincent J, Carrier L, Carrier L, Walker L, Linke W, Stienen G, van der Velden J
CIRC-HEART FAIL. 2009;2(3):233-242.

Beta-adrenergic stimulation and myocardial function in the failing heart
El-Armouche A, Eschenhagen T
HEART FAIL REV. 2009;14(4):225-41.

Comparing the chemical biology of NO and HNO
Flores-Santana W, Switzer C, Ridnour L, Basudhar D, Mancardi D, Donzelli S, Thomas D, Miranda K, Fukuto J, Wink D
ARCH PHARM RES. 2009;32(8):1139-53.

A new polymorphism in human calmodulin III gene promoter is a potential modifier gene for familial hypertrophic cardiomyopathy.
Friedrich F, Bausero P, Sun Y, Treszl A, Krämer E, Juhr D, Richard P, Wegscheider K, Schwartz K, Brito D, Arbustini E, Waldenström A, Isnard R, Komajda M, Eschenhagen T, Carrier L
EUR HEART J. 2009;30(13):1648-1655.

[Fingolimod - a new immunomodulator]
Friedrich F, Eschenhagen T
DEUT MED WOCHENSCHR. 2009;134(42):2127-2131.

Fingolimod - ein neuer Immunmodulator
Friedrich F, Eschenhagen T
DEUT MED WOCHENSCHR. 2009;134(42):2127-31.

Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation.
Greiser M, Neuberger H, Harks E, El-Armouche A, Boknik P, de Haan S, Verheyen F, Verheule S, Schmitz W, Ravens U, Nattel S, Allessie M, Dobrev D, Schotten U
J MOL CELL CARDIOL. 2009;46(3):385-394.

Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine.
Hu X, Xu X, Zhu G, Atzler D, Kimoto M, Chen J, Schwedhelm E, Lüneburg N, Böger R, Zhang P, Chen Y
CIRCULATION. 2009;120(22):2222-2229.

Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer.
Johnsen S, Güngör C, Prenzel T, Riethdorf S, Riethdorf L, Taniguchi-Ishigaki N, Rau T, Tursun B, Furlow J, Sauter G, Scheffner M, Pantel K, Gannon F, Bach I
CANCER RES. 2009;69(1):128-136.

The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice.
Kroeger I, Erhardt A, Abt D, Fischer M, Biburger M, Rau T, Neuhuber W, Tiegs G
J HEPATOL. 2009;51(2):342-353.

Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.
Leypoldt F, Choe C, Gelderblom M, von Leitner E, Atzler D, Schwedhelm E, Gerloff C, Sydow K, Böger R, Magnus T
PLOS ONE. 2009;4(10):7337.

Plasma asymmetric dimethylarginine, L-arginine and left ventricular structure and function in a community-based sample.
Lieb W, Benndorf R, Benjamin E, Sullivan Lisa M, Maas R, Xanthakis V, Schwedhelm E, Aragam J, Schulze F, Böger R, Vasan R
ATHEROSCLEROSIS. 2009;204(1):282-287.

ADMA and the role of the genes: Lessons from genetically modified animals and human gene polymorphisms.
Maas R, Böger R, Lüneburg N
PHARMACOL RES. 2009;60(6):475-480.

Polymorphisms in the promoter region of the dimethylarginine dimethylaminohydrolase 2 gene are associated with prevalence of hypertension.
Maas R, Erdmann J, Lüneburg N, Stritzke J, Schwedhelm E, Meisinger C, Peters A, Weil J, Schunkert H, Böger R, Lieb W
PHARMACOL RES. 2009;60(6):488-493.

Association of the Endogenous Nitric Oxide Synthase Inhibitor ADMA With Carotid Artery Intimal Media Thickness in the Framingham Heart Study Offspring Cohort.
Maas R, Xanthakis V, Polak J, Schwedhelm E, Sullivan Lisa M, Benndorf R, Schulze F, Vasan R, Wolf P, Böger R, Seshadri S
STROKE. 2009;40(8):2715-2719.

Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous?
Martens-Lobenhoffer J, Schwedhelm E, Tsikas D
J CHROMATOGR B. 2009;877(27):3261-3266.

Plasminogen activator inhibitor type 1 up-regulation is associated with skeletal muscle atrophy and associated fibrosis.
Naderi J, Bernreuther C, Grabinski N, Putman C, Henkel B, Bell G, Glatzel M, Sultan K
AM J PATHOL. 2009;175(2):763-771.

Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study.
Ostad M, Eggeling S, Tschentscher P, Schwedhelm E, Böger R, Wenzel P, Meinertz T, Munzel T, Warnholtz A
ATHEROSCLEROSIS. 2009;205(1):227-232.

Capturing adenylyl cyclases as potential drug targets.
Pierre S, Eschenhagen T, Geisslinger G, Scholich K
NAT REV DRUG DISCOV. 2009;8(4):321-335.

Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study.
Pikula A, Böger R, Beiser A, Maas R, DeCarli C, Schwedhelm E, Himali J, Schulze F, Au R, Kelly-Hayes M, Kase C, Vasan R, Wolf P, Seshadri S
STROKE. 2009;40(9):2959-2964.

Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study.
Rau T, Wuttke H, Michels L, Werner U, Bergmann K, Kreft M, Fromm M, Eschenhagen T
CLIN PHARMACOL THER. 2009;85(3):269-272.

Ethnic-specific correlations of visfatin with circulating markers of endothelial inflammation and function.
Reimann M, Ziemssen T, Huisman H, Schutte R, Malan L, Rooyen V, Böger R, Böger R, Malan N, Schutte A
OBESITY. 2009;17(12):2210-2215.

A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function.
Rudolph V, Rudolph T, Kubala L, Clauberg N, Maas R, Pekarova M, Klinke A, Lau D, Szöcs K, Meinertz T, Böger R, Baldus S
FREE RADICAL BIO MED. 2009;47(11):1584-1590.

Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
Schmechel A, Grimm M, El-Armouche A, Höppner G, Schwoerer A, Ehmke H, Eschenhagen T
CARDIOVASC RES. 2009;82(1):100-106.

Transplantation of bone marrow-derived stem cells improves myocardial diastolic function: strain rate imaging in a model of hibernating myocardium.
Schneider C, Jaquet K, Geidel S, Rau T, Malisius R, Boczor S, Zienkiewicz T, Kuck K, Krause K
J AM SOC ECHOCARDIOG. 2009;22(10):1180-1189.

L-Arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma triglycerides.
Schulze F, Glos S, Petruschka D, Altenburg C, Maas R, Benndorf R, Schwedhelm E, Beil U, Böger R
NUTR RES. 2009;29(5):291-297.

Asymmetric dimethylarginine predicts outcome and time of stay in hospital in patients attending an internal medicine emergency room.
Schulze F, Vollert J, Maas R, Müller R, Schwedhelm E, Müller C, Böger R, Möckel M
CLIN CHIM ACTA. 2009;401(1-2):20-24.

Extensive characterization of the human DDAH1 transgenic mice.
Schwedhelm E, von Leitner E, Atzler D, Schmitz C, Jacobi J, Meinertz T, Münzel T, Baldus S, Cooke J, Böger R, Maas R, Sydow K
PHARMACOL RES. 2009;60(6):494-502.

Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort.
Schwedhelm E, Xanthakis V, Maas R, Sullivan Lisa M, Schulze F, Riederer U, Benndorf R, Böger R, Vasan R
CLIN CHEM. 2009.

Development and validation of an RP-HPLC method for the analysis of anthraquinones in noni fruits and leaves
Shixin D, Jarakae Jensen C, Basar S, Westendorf J, Westendorf J
FOOD CHEM. 2009;116(2):505-508.

A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria.
Sibal L, Agarwal S, Schwedhelm E, Lüneburg N, Böger R, Home P
CARDIOVASC DIABETOL. 2009;8:27.

Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Vignier N, Schlossarek S, Fraysse B, Mearini G, Krämer E, Pointu H, Mougenot N, Guiard J, Reimer R, Hohenberg H, Schwartz K, Vernet M, Eschenhagen T, Carrier L
CIRC RES. 2009;105(3):239-248.

Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein.
Weiss J, Sauer A, Herzog M, Böger R, Haefeli W, Benndorf R
PHARMACOLOGY. 2009;84(5):264-270.

Pharmacogenetic characteristics of patients with complicated phenprocoumon dosing.
Werner D, Werner U, Wuerfel A, Grosch A, Lestin H, Eschenhagen T, Rau T
EUR J CLIN PHARMACOL. 2009.

A Double-Blind Clinical Safety Study of Noni Fruit Juice
West B, White L, Palu A, Westendorf J, Westendorf J
Pacific Health Dial. 2009;15(2):21-32.

The benefits of noni juice: an epidemiological evaluation in Europe
Westendorf J, Mettlich C
J Med Food Plants. 2009;1(2):64-67.

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure
Albers S, Meibohm B, Mir T, Läer S
BRIT J CLIN PHARMACO. 2008;65(4):511-522.

Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease.
Arlt S, Schulze F, Eichenlaub M, Maas R, Lehmbeck J, Schwedhelm E, Jahn H, Böger R
DEMENT GERIATR COGN. 2008;26(1):58-64.

Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy.
Bahrudin U, Morisaki H, Morisaki T, Ninomiya H, Higaki K, Nanba E, Igawa O, Takashima S, Mizuta E, Miake J, Yamamoto Y, Shirayoshi Y, Kitakaze M, Carrier L, Hisatome I
J MOL BIOL. 2008;384(4):896-907.

Expression and distribution of heat shock proteins in the heart of transported pigs.
Bao E, Sultan K, Nowak B, Hartung J
CELL STRESS CHAPERON. 2008;13(4):459-466.

Pleiotropic effects of telmisartan: still more to come?
Benndorf R, Böger R
J HYPERTENS. 2008;26(5):854-856.

Long-term effect on body composition and metabolic parameters after treatment with recombinant human growth hormone (r-hGH) in HIV-1 infected patients with lipodystrophy.
Bickel M, Zangos S, Lutz T, Eisen J, Knecht G, Goebel F, Crespi C, Jacobi V, Staszewski S, Klauke S
SCAND J INFECT DIS. 2008;40(1):36-39.

P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.
Bierend A, Rau T, Maas R, Schwedhelm E, Böger R
BRIT J CLIN PHARMACO. 2008;65(4):540-547.

L-Arginine therapy in cardiovascular pathologies: beneficial or dangerous?
Böger R
CURR OPIN CLIN NUTR. 2008;11(1):55-61.

Introducing the first polymer-free leflunomide eluting stent.
Deuse T, Erben R, Ikeno F, Behnisch B, Böger R, Connolly A, Reichenspurner H, Bergow C, Pelletier M, Robbins R, Schrepfer S
ATHEROSCLEROSIS. 2008;200(1):126-134.

Bisoprolol vs. carvedilol in elderly patients with heart failure: rationale and design of the CIBIS-ELD trial.
Düngen H, Apostolovi S, Inkrot S, Tahirovi E, Krackhardt F, Pavlovi M, Putnikovi B, Lainscak M, Gelbrich G, Edelmann F, Wachter R, Eschenhagen T, Waagstein F, Follath F, Rauchhaus M, Haverkamp W, Osterziel K, Dietz R
CLIN RES CARDIOL. 2008;97(9):578-586.

Altered myocardial gene expression reveals possible maladaptive processes in heterozygous and homozygous cardiac myosin-binding protein C knockout mice.
Eijssen L, van den Bosch B, Vignier N, Lindsey P, van den Burg C, Carrier L, Doevendans P, van der Vusse G, Smeets H
GENOMICS. 2008;91(1):52-60.

Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy.
El-Armouche A, Wittköpper K, Degenhardt F, Weinberger F, Didié M, Melnychenko I, Grimm M, Peeck M, Zimmermann W, Unsöld B, Hasenfuss G, Dobrev D, Eschenhagen T
CARDIOVASC RES. 2008;80(3):396-406.

Beta-adrenergic signaling in heart failure-adapt or die.
Eschenhagen T
NAT MED. 2008;14(5):485-487.

[25 years of progress in pharmacology: many innovations--are you up to date?]
Eschenhagen T, Rau T
MMW Fortschr Med. 2008;150(48):130, 132, 134.

Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
Galle J, Schwedhelm E, Pinnetti S, Böger R, Wanner C
NEPHROL DIAL TRANSPL. 2008;23(10):3174-3183.

Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload.
Grote-Wessels S, Baba H, Boknik P, El-Armouche A, Fabritz L, Gillmann H, Kucerova D, Matus M, Müller F, Neumann J, Schmitz M, Stümpel F, Theilmeier G, Wohlschlaeger J, Schmitz W, Kirchhefer U
CARDIOVASC RES. 2008;79(3):464-471.

Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins.
Huellner M, Schrepfer S, Weyand M, Weiner H, Rau I, Eschenhagen T, Rau T
FASEB J. 2008;22(7):2561-2568.

Role of asymmetric dimethylarginine for angiotensin II-induced target organ damage in mice.
Jacobi J, Maas R, Cordasic N, Koch K, Schmieder R, Böger R, Hilgers K
AM J PHYSIOL-HEART C. 2008;294(2):1058-1066.

Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II.
Kirchhoff F, Krebs C, Abdulhag U, Meyer-Schwesinger C, Maas R, Helmchen U, Hilgers K, Wolf G, Stahl R, Wenzel U
KIDNEY INT. 2008;73(5):643-650.

Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium.
Kockskämper J, Khafaga M, Grimm M, Elgner A, Walther S, Kockskämper A, von Lewinski D, Post H, Grossmann M, Dörge H, Gottlieb P, Sachs F, Eschenhagen T, Schöndube F, Pieske B
CARDIOVASC RES. 2008;79(4):642-651.

The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms.
Kockskämper J, von Lewinski D, Khafaga M, Elgner A, Grimm M, Eschenhagen T, Gottlieb P, Sachs F, Pieske B
PROG BIOPHYS MOL BIO. 2008;97(2-3):250-267.

Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.
Köllermann J, Weikert S, Schostak M, Kempkensteffen C, Kleinschmidt K, Rau T, Pantel K
J CLIN ONCOL. 2008;26(30):4928-4933.

Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/ AKT pathway.
Krüger M, Sachse C, Zimmermann W, Eschenhagen T, Klede S, Linke W
CIRC RES. 2008;102(4):439-447.

Cardiac Myosin-binding protein C modulates the tuning of the molecular motor in the heart.
Lecarpentier Y, Vignier N, Oliviero P, Guellich A, Carrier L, Coirault C
BIOPHYS J. 2008;95(2):720-728.

Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.
Maas R, Schwedhelm E, Kahl L, Li H, Benndorf R, Lüneburg N, Förstermann U, Böger R
CLIN CHEM. 2008;54(2):292-300.

The ubiquitin-proteasome system in cardiac dysfunction.
Mearini G, Schlossarek S, Willis M, Carrier L
BBA-MOL BASIS DIS. 2008;1782(12):749-763.

Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone).
Pergolizzi J, Böger R, Budd K, Dahan A, Erdine S, Hans G, Kress H, Langford R, Likar R, Raffa R, Sacerdote P
PAIN PRACT. 2008;8(4):287-313.

Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
Pexa A, Böger R, Henle T, Schwedhelm E, Deussen A
BRIT J NUTR. 2008;99(5):993-999.

Intramyocardial transplantation of bone marrow-derived stem cells: ultrasonic strain rate imaging in a model of hibernating myocardium.
Schneider C, Krause K, Jaquet K, Geidel S, Malisius R, Boczor S, Rau T, Zienkiewicz T, Hennig D, Kuck K
J CARD FAIL. 2008;14(10):861-872.

Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, Spickler W, Schulze F, Böger R
BRIT J CLIN PHARMACO. 2008;65(1):51-59.

Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
Schwoerer A, Melnychenko I, Goltz D, Hedinger N, Broichhausen I, El-Armouche A, Eschenhagen T, Volk T, Ehmke H
J MOL CELL CARDIOL. 2008;45(5):633-641.

Mechanical unloading of the rat heart involves marked changes in the protein kinase-phosphatase balance.
Schwoerer A, Neuber C, Schmechel A, Melnychenko I, Mearini G, Boknik P, Kirchhefer U, Schmitz W, Ehmke H, Eschenhagen T, El-Armouche A
J MOL CELL CARDIOL. 2008;45(6):846-852.

Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension.
Sharma S, Sud N, Wiseman D, Carter A, Kumar S, Hou Y, Rau T, Wilham J, Harmon C, Oishi P, Fineman J, Black S
AM J PHYSIOL-LUNG C. 2008;294(1):46-56.

ATP-binding cassette transporters in human heart failure.
Solbach T, Paulus B, Weyand M, Eschenhagen T, Zolk O, Fromm M
N-S ARCH PHARMACOL. 2008;377(3):231-243.

Hindbrain administration of estradiol inhibits feeding and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats.
Thammacharoen S, Lutz T, Geary N, Asarian L
ENDOCRINOLOGY. 2008;149(4):1609-1617.

Real-time myocardial contrast echocardiography for assessing perfusion and function in healthy and infarcted wistar rats.
Wasmeier G, Zimmermann W, Schineis N, Melnychenko I, Voigt J, Eschenhagen T, Flachskampf F, Daniel W, Nixdorff U
ULTRASOUND MED BIOL. 2008;34(1):47-55.

Olanzapin
Wittköpper K, El-Armouche A, Eschenhagen T
DEUT MED WOCHENSCHR. 2008;133(39):1958-62.

[Olanzapine]
Wittköpper K, El-Armouche A, Eschenhagen T
DEUT MED WOCHENSCHR. 2008;133(39):1958-1962.

Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.
Zhang Y, Zhang M, Sears C, Emanuel K, Redwood C, El-Armouche A, Kranias E, Casadei B
CIRC RES. 2008;102(2):242-249.

Activation of negative regulators of the hypoxia-inducible factor (HIF) pathway in human end-stage heart failure.
Zolk O, Solbach T, Eschenhagen T, Weidemann A, Fromm M
BIOCHEM BIOPH RES CO. 2008;376(2):315-320.

Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension.
Bajcetic M, Benndorf R, Appel D, Schwedhelm E, Schulze F, Riekhof D, Maas R, Böger R
J CLIN PHARMACOL. 2007;47(3):295-304.

Telmisartan improves endothelial function in patients with essential hypertension.
Benndorf R, Appel D, Maas R, Schwedhelm E, Wenzel U, Böger R
J CARDIOVASC PHARM. 2007;50(4):367-371.

Mobilization of putative high-proliferative-potential endothelial colony-forming cells during antihypertensive treatment in patients with essential hypertension.
Benndorf R, Gehling U, Appel D, Maas R, Schwedhelm E, Schlagner K, Silberhorn E, Hossfeld D, Rogiers X, Böger R
STEM CELLS DEV. 2007;16(2):329-338.

Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine.
Böger G, Rudolph T, Maas R, Schwedhelm E, Dumbadze E, Bierend A, Benndorf R, Böger R
J AM COLL CARDIOL. 2007;49(23):2274-2282.

The pharmacodynamics of L-arginine.
Böger R
J NUTR. 2007;137(6 Suppl 2):.

Cardiac myosin-binding protein C in the heart.
Carrier L
Arch Mal Coeur Vaiss. 2007;100(3):238-243.

[Dopamine: less important in emergency medicine?]
El-Armouche A, Eschenhagen T
DEUT MED WOCHENSCHR. 2007;132(49):2654.

Long-term beta-adrenergic stimulation leads to downregulation of protein phosphatase inhibitor-1 in the heart.
El-Armouche A, Gocht F, Jaeckel E, Wittköpper K, Peeck M, Eschenhagen T
EUR J HEART FAIL. 2007;9(11):1077-1080.

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure.
El-Armouche A, Pohlmann L, Schlossarek S, Starbatty J, Yeh Y, Nattel S, Dobrev D, Eschenhagen T, Carrier L
J MOL CELL CARDIOL. 2007;43(2):223-229.

Adenovirus-delivered short hairpin RNA targeting PKCalpha improves contractile function in reconstituted heart tissue.
El-Armouche A, Singh J, Naito H, Wittköpper K, Didié M, Laatsch A, Zimmermann W, Eschenhagen T
J MOL CELL CARDIOL. 2007;43(3):371-376.

Plasma concentrations of asymmetric dimethylarginine (ADMA) in metabolic syndrome.
Garcia R, Perez M, Maas R, Schwedhelm E, Böger R, López-Jaramillo P
INT J CARDIOL. 2007;122(2):176-178.

Reduced contractile response to alpha1-adrenergic stimulation in atria from mice with chronic cardiac calmodulin kinase II inhibition.
Grimm M, El-Armouche A, Zhang R, Anderson M, Eschenhagen T
J MOL CELL CARDIOL. 2007;42(3):643-652.

Regulation of cardiac cAMP synthesis and contractility by nucleoside diphosphate kinase B/G protein beta gamma dimer complexes.
Hippe H, Luedde M, Lutz S, Koehler H, Eschenhagen T, Frey N, Katus H, Wieland T, Niroomand F
CIRC RES. 2007;100(8):1191-1199.

Impact of atorvastatin treatment on platelet-activating factor acetylhydrolase and 15-F(2trans)-isoprostane in hypercholesterolaemic patients.
Kom G, Schwedhelm E, Maas R, Schneider L, Benndorf R, Böger R
BRIT J CLIN PHARMACO. 2007;63(6):672-679.

Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery.
Maas R, Dentz L, Schwedhelm E, Thoms W, Kuß O, Hiltmeyer N, Haddad M, Klöss T, Standl T, Böger R
CRIT CARE MED. 2007;35(8):1876-1881.

Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia.
Maas R, Quitzau K, Schwedhelm E, Spieker L, Rafflenbeul W, Steenpass A, Lüscher T, Böger R
ATHEROSCLEROSIS. 2007;191(1):211-219.

Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data.
Maas R, Schulze F, Baumert J, Löwel H, Hamraz K, Schwedhelm E, Koenig W, Böger R
CLIN CHEM. 2007;53(4):693-701.

A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue.
Maas R, Tan-Andreesen J, Schwedhelm E, Schulze F, Böger R
J CHROMATOGR B. 2007;851(1-2):220-228.

Cardiac myosin-binding protein C is required for complete relaxation in intact myocytes.
Pohlmann L, Kröger I, Vignier N, Schlossarek S, Krämer E, Coirault C, Sultan K, El-Armouche A, Winegrad S, Eschenhagen T, Carrier L
CIRC RES. 2007;101(9):928-938.

Asymmetric dimethylarginine is associated with parameters of glucose metabolism in Caucasian but not in African women from South Africa.
Reimann M, Schutte A, Malan N, Schwarz P, Benndorf R, Schulze F, Böger R
EXP CLIN ENDOCR DIAB. 2007;115(9):600-605.

Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.
Riethdorf S, Fritsche H, Müller V, Rau T, Schindlbeck C, Rack B, Janni W, Coith C, Beck K, Jänicke F, Jackson S, Gornet T, Cristofanilli M, Pantel K
CLIN CANCER RES. 2007;13(3):920-928.

The effect of the volatile oil from ginger rhizomes (Zingiber officinale), its fractions and isolated compounds on the 5-HT3 receptor complex and the serotoninergic system of the rat ileum.
Riyazi A, Hensel A, Bauer K, Geissler N, Schaaf S, Verspohl E
PLANTA MED. 2007;73(4):355-362.

Acute effects of various fast-food meals on vascular function and cardiovascular disease risk markers: the Hamburg Burger Trial.
Rudolph T, Ruempler K, Schwedhelm E, Tan-Andresen J, Riederer U, Böger R, Maas R
AM J CLIN NUTR. 2007;86(2):334-340.

Attenuation of cardiac remodelling by endocardial injection of erythropoietin: ultrasonic strain-rate imaging in a model of hibernating myocardium.
Schneider C, Jaquet K, Malisius R, Geidel S, Bahlmann E, Boczor S, Rau T, Antz M, Kuck K, Krause K
EUR HEART J. 2007;28(4):499-509.

Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
Schrepfer S, Deuse T, Sultan K, Haddad M, Böger R, Münzel T, Schäfer H, Pelletier M, Robbins R, Reichenspurner H
CARDIOLOGY. 2007;108(2):128-137.

High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma.
Schwedhelm E, Maas R, Tan-Andresen J, Schulze F, Riederer U, Böger R
J CHROMATOGR B. 2007;851(1-2):211-219.

An additive effect of endothelial nitric oxide synthase gene polymorphisms contributes to the severity of atherosclerosis in patients on dialysis.
Spoto B, Benedetto F, Testa A, Tripepi G, Mallamaci F, Maas R, Boeger R, Zoccali C
AM J HYPERTENS. 2007;20(7):758-763.

Mechanisms of disease: L-arginine in coronary atherosclerosis--a clinical perspective.
Tousoulis D, Böger R, Antoniades C, Siasos G, Stefanadi E, Stefanadis C
NAT CLIN PRACT CARD. 2007;4(5):274-283.

AT1-receptor blockade with irbesartan improves peripheral but not coronary endothelial dysfunction in patients with stable coronary artery disease.
Warnholtz A, Ostad M, Heitzer T, Thuneke F, Fröhlich M, Tschentscher P, Schwedhelm E, Böger R, Meinertz T, Munzel T
ATHEROSCLEROSIS. 2007;194(2):439-445.

Reproducibility of transthoracic echocardiography in small animals using clinical equipment.
Wasmeier G, Melnychenko I, Voigt J, Zimmermann W, Eschenhagen T, Schineis N, Reulbach U, Flachskampf F, Daniel W, Nixdorff U
CORONARY ARTERY DIS. 2007;18(4):283-291.

Arterial wave reflections and determinants of endothelial function a hypothesis based on peripheral mode of action.
Weber T, Maas R, Auer J, Lamm G, Lassnig E, Rammer M, O'Rourke M, Böger R, Eber B
AM J HYPERTENS. 2007;20(3):256-262.

Toxicological and analytical investigations of noni (Morinda citrifolia) fruit juice.
Westendorf J, Harms-Effenberger K, Iznaguen H, Basar S
J AGR FOOD CHEM. 2007;55(2):529-537.

Development of a biological ventricular assist device: preliminary data from a small animal model.
Yildirim Y, Naito H, Didié M, Karikkineth B, Biermann D, Eschenhagen T, Zimmermann W
CIRCULATION. 2007;116(11):16-23.

Embryonic stem cells for cardiac muscle engineering.
Zimmermann W, Eschenhagen T
TRENDS CARDIOVAS MED. 2007;17(4):134-140.

Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections.
Zoccali C, Maas R, Cutrupi S, Pizzini P, Finocchiaro P, Cambareri F, Panuccio V, Martorano C, Schulze F, Enia G, Tripepi G, Böger R
NEPHROL DIAL TRANSPL. 2007;22(3):801-806.

Telmisartan improves insulin sensitivity in nondiabetic patients with essential hypertension.
Benndorf R, Rudolph T, Appel D, Schwedhelm E, Maas R, Schulze F, Silberhorn E, Böger R
METABOLISM. 2006;55(9):1159-1164.

Postocclusive reactive hyperemia inversely correlates with urinary 15-F2t-isoprostane levels in systemic sclerosis.
Cracowski J, Kom G, Salvat-Melis M, Renversez J, McCord G, Boignard A, Carpentier P, Schwedhelm E
FREE RADICAL BIO MED. 2006;40(10):1732-1737.

Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes.
El-Armouche A, Bednorz A, Pamminger T, Ditz D, Didié M, Dobrev D, Eschenhagen T
BIOCHEM BIOPH RES CO. 2006;346(3):700-706.

Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation.
El-Armouche A, Boknik P, Eschenhagen T, Carrier L, Knaut M, Ravens U, Dobrev D
CIRCULATION. 2006;114(7):670-680.

The MLCK-mediated alpha1-adrenergic inotropic effect in atrial myocardium is negatively modulated by PKCepsilon signaling.
Grimm M, Mahnecke N, Soja F, El-Armouche A, Haas P, Treede H, Reichenspurner H, Eschenhagen T
BRIT J PHARMACOL. 2006;148(7):991-1000.

Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.
Heitzer T, Rudolph V, Schwedhelm E, Karstens M, Sydow K, Ortak M, Tschentscher P, Meinertz T, Böger R, Baldus S
ARTERIOSCL THROM VAS. 2006;26(7):1648-1652.

Noni juice protects the liver.
Jensen C, Westendorf J, Wang M, Wadsworth D
EUR J GASTROEN HEPAT. 2006;18(5):575-577.

Increased urinary excretion of 8-iso-prostaglandin F2alpha in patients with HFE-related hemochromatosis: a case-control study.
Kom G, Schwedhelm E, Nielsen P, Böger R
FREE RADICAL BIO MED. 2006;40(7):1194-1200.

Complications of non-compaction of the left ventricular myocardium in a paediatric population: a prospective study.
Lilje C, Rázek V, Joyce J, Rau T, Finckh B, Weiss F, Habermann C, Rice J, Weil J
EUR HEART J. 2006;27(15):1855-1860.

Atorvastatin desensitizes beta-adrenergic signaling in cardiac myocytes via reduced isoprenylation of G-protein gamma-subunits.
Mühlhäuser U, Zolk O, Rau T, Münzel F, Wieland T, Eschenhagen T
FASEB J. 2006;20(6):785-787.

Event-recorder monitoring in the diagnosis of atrial fibrillation in symptomatic patients: subanalysis of the SOPAT trial.
Patten-Hamel M, Maas R, Karim A, Müller H, Simonovsky R, Meinertz T
J CARDIOVASC ELECTR. 2006;17(11):1216-1220.

The 2988G>A polymorphism affects splicing of a CYP2D6 minigene.
Rau T, Diepenbruck S, Diepenbruck I, Eschenhagen T
CLIN PHARMACOL THER. 2006;80(5):555-560.

High-dose methotrexate in pediatric acute lymphoblastic leukemia: impact of ABCC2 polymorphisms on plasma concentrations.
Rau T, Erney B, Göres R, Eschenhagen T, Beck J, Langer T
CLIN PHARMACOL THER. 2006;80(5):468-476.

Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C.
Sahin B, Shu H, Fernandez J, El-Armouche A, Molkentin J, Nairn A, Bibb J
J BIOL CHEM. 2006;281(34):24322-24335.

Asymmetric dimethylarginine is an independent risk factor for coronary heart disease: results from the multicenter Coronary Artery Risk Determination investigating the Influence of ADMA Concentration (CARDIAC) study.
Schulze F, Lenzen H, Hanefeld C, Bartling A, Osterziel K, Goudeva L, Schmidt-Lucke C, Kusus M, Maas R, Schwedhelm E, Strödter D, Simon B, Mügge A, Daniel W, Tillmanns H, Maisch B, Streichert T, Böger R
AM HEART J. 2006;152(3):1-8.

Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum.
Schulze F, Schwedhelm E, Maas R, Böger R
J CHROMATOGR B. 2006;831(1-2):333.

Obesity is associated with a slower response to initial phenprocoumon therapy whereas CYP2C9 genotypes are not.
Schwabedissen Z, Meyer C, Mevissen V, Schmitz F, Woodruff S, Rau T, Rau T, Zerres K, Hoffmann R, Ortlepp J
EUR J CLIN PHARMACOL. 2006;62(9):713-720.

Direct technique for the fabrication of acrylic provisional restorations.
Schwedhelm E
J Contemp Dent Pract. 2006;7(1):157-173.

A technique for locating implant abutment screws of posterior cement-retained metal-ceramic restorations with ceramic occlusal surfaces.
Schwedhelm E, Raigrodski A
J PROSTHET DENT. 2006;95(2):165-167.

Quantification of hormone-induced atrophy of large myotubes from C2C12 and L6 cells: atrophy-inducible and atrophy-resistant C2C12 myotubes.
Sultan K, Henkel B, Terlou M, Haagsman H
AM J PHYSIOL-CELL PH. 2006;290(2):650-659.

Noni juice is not hepatotoxic.
West B, Jensen C, Westendorf J
WORLD J GASTROENTERO. 2006;12(22):3616-3619.

Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality.
Böger R, Maas R, Schulze F, Schwedhelm E
CLIN CHEM LAB MED. 2005;43(10):1124-1129.

ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
Böger R, Schwedhelm E, Maas R, Quispe-Bravo S, Skamira C
VASC MED. 2005;10(1):97-102.

FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.
Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schwedhelm E, Böger R, Schäfer H, Detter C, Reichenspurner H
J HEART LUNG TRANSPL. 2005;24(11):1844-1854.

Regulation of osteoblastic phenotype and gene expression by hop-derived phytoestrogens.
Effenberger K, Johnsen S, Monroe D, Spelsberg T, Westendorf J
J STEROID BIOCHEM. 2005;96(5):387-399.

Identification of adverse drug reactions by evaluation of a prescription database, demonstrated for "risk of bleeding".
Gaus W, Westendorf J, Diebow R, Kieser M
METHOD INFORM MED. 2005;44(5):697-703.

Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium.
Grimm M, Haas P, Willipinski-Stapelfeldt B, Zimmermann W, Rau T, Pantel K, Weyand M, Eschenhagen T
CARDIOVASC RES. 2005;65(1):211-220.

Bioavailability of diclofenac potassium at low doses.
Hinz B, Chevts J, Renner B, Wuttke H, Rau T, Schmidt A, Szelenyi I, Brune K, Werner U
BRIT J CLIN PHARMACO. 2005;59(1):80-84.

Elevation of asymmetric dimethylarginine in patients with unstable angina and recurrent cardiovascular events.
Krempl T, Maas R, Sydow K, Meinertz T, Böger R, Kähler J
EUR HEART J. 2005;26(18):1846-1851.

Pharmacotherapies and their influence on asymmetric dimethylargine (ADMA).
Maas R
VASC MED. 2005;10(1):49-57.

Elevation of asymmetrical dimethylarginine (ADMA) and coronary artery disease in men with erectile dysfunction.
Maas R, Wenske S, Zabel M, Ventura R, Schwedhelm E, Steenpass A, Klemm H, Noldus J, Böger R
EUR UROL. 2005;48(6):1002-1004.

Plasma concentrations of N-terminal brain natriuretic peptide in healthy children, adolescents, and young adults: effect of age and gender.
Mir T, Flato M, Falkenberg J, Haddad M, Budden R, Weil J, Albers S, Laer S
PEDIATR CARDIOL. 2005;27(1):73-77.

Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity.
Müller V, Stahmann N, Riethdorf S, Rau T, Zabel T, Goetz A, Jänicke F, Pantel K
CLIN CANCER RES. 2005;11(10):3678-3685.

Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension.
Perticone F, Sciacqua A, Maio R, Perticone M, Maas R, Boger R, Tripepi G, Sesti G, Zoccali C
J AM COLL CARDIOL. 2005;46(3):518-523.

Effect of syncope-related traumatic injuries on the diagnostic evaluation and syncope recurrence of patients with syncope and apparently normal hearts.
Schuchert A, Maas R, Mortensen K, Aydin M, Kretzschmar C, Meinertz T
AM J CARDIOL. 2005;95(9):1101-1103.

Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects.
Schulze F, Maas R, Freese R, Schwedhelm E, Silberhorn E, Böger R
EUR J CLIN INVEST. 2005;35(10):622-626.

Quantification of ADMA: analytical approaches.
Schwedhelm E
VASC MED. 2005;10(1):89-95.

Liquid chromatography-tandem mass spectrometry method for the analysis of asymmetric dimethylarginine in human plasma.
Schwedhelm E, Tan-Andresen J, Maas R, Riederer U, Schulze F, Böger R
CLIN CHEM. 2005;51(7):1268-1271.

Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease.
Spoto B, Benedetto F, Testa A, Tripepi G, Mallamaci F, Maas R, Boeger R, Zoccali C, Parlongo R, Pisano A
AM J HYPERTENS. 2005;18(12 Pt 1):1549-1555.

The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease.
Testa A, Spoto B, Tripepi G, Mallamaci F, Malatino L, Fatuzzo P, Maas R, Boeger R, Zoccali C
J HYPERTENS. 2005;23(10):1825-1830.

Unusual collision-induced dissociation of fluorated and non-fluorated alpha-nitrotoluene analogs in a gas chromatograph triple-stage quadrupole mass spectrometer under electron-capturing negative-ion chemical ionization conditions.
Tsikas D, Schwedhelm E, Frölich J
J CHROMATOGR A. 2005;1067(1-2):337-345.

Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells.
Willipinski-Stapelfeldt B, Riethdorf S, Assmann V, Woelfle U, Rau T, Sauter G, Heukeshoven J, Pantel K
CLIN CANCER RES. 2005;11(22):8006-8014.

Determination of NG,NG-dimethyl-L-arginine, an endogenous NO synthase inhibitor, by gas chromatography-mass spectrometry.
Albsmeier J, Schwedhelm E, Schulze F, Kastner M, Böger R
J CHROMATOGR B. 2004;809(1):59-65.

[Biomarkers as prognostic factors in pulmonary arterial hypertension. Rationale and study design]
Cracowski J, Yaici A, Sitbon O, Reynaud-Gaubert M, Renversez J, Pison C, Faure P, Cracowski C, Chouri N, Chaouat A, Chabot F, Schwedhelm E, Maas R, Degano B, Mornex J, Humbert M
REV MAL RESPIR. 2004;21(6 Pt 1):1137-1143.

FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.
Deuse T, Schrepfer S, Schäfer H, Koch-Nolte F, Schwedhelm E, Böger R, Reichenspurner H
TRANSPLANTATION. 2004;78(1):71-77.

Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism.
Eisele G, Schwedhelm E, Schieffer B, Tsikas D, Böger R
J CARDIOVASC PHARM. 2004;43(4):514-521.

Ouabain treatment is associated with upregulation of phosphatase inhibitor-1 and Na+/Ca(2+)-exchanger and beta-adrenergic sensitization in rat hearts.
El-Armouche A, Jaeckel E, Boheler K, Boknik P, Hertle B, Neumann J, Eschenhagen T
BIOCHEM BIOPH RES CO. 2004;318(1):219-226.

Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts.
El-Armouche A, Pamminger T, Ditz D, Zolk O, Eschenhagen T
CARDIOVASC RES. 2004;61(1):87-93.

Human homozygous R403W mutant cardiac myosin presents disproportionate enhancement of mechanical and enzymatic properties.
Keller D, Coirault C, Rau T, Cheav T, Weyand M, Amann K, Lecarpentier Y, Richard P, Eschenhagen T, Carrier L
J MOL CELL CARDIOL. 2004;36(3):355-362.

Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia.
Maas R, Böger R, Schwedhelm E, Casas J, López-Jaramillo P, Serrano N, Díaz L
JAMA-J AM MED ASSOC. 2004;291(7):823-824.

Analysis of the relationship between norepinephrine and asymmetric dimethyl arginine levels among patients with end-stage renal disease.
Mallamaci F, Tripepi G, Maas R, Malatino L, Böger R, Zoccali C
J AM SOC NEPHROL. 2004;15(2):435-441.

Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.
Patten-Hamel M, Maas R, Bauer P, Lüderitz B, Sonntag F, Dluzniewski M, Hatala R, Opolski G, Müller H, Meinertz T
EUR HEART J. 2004;25(16):1395-1404.

CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study.
Rau T, Wohlleben G, Wuttke H, Thuerauf N, Lunkenheimer J, Lanczik M, Eschenhagen T
CLIN PHARMACOL THER. 2004;75(5):386-393.

Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease.
Schieffer B, Bünte C, Witte J, Hoeper K, Böger R, Schwedhelm E, Drexler H
J AM COLL CARDIOL. 2004;44(2):362-368.

Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay.
Schulze F, Wesemann R, Schwedhelm E, Sydow K, Albsmeier J, Cooke J, Böger R
CLIN CHEM LAB MED. 2004;42(12):1377-1383.

Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study.
Schwedhelm E, Bartling A, Lenzen H, Tsikas D, Maas R, Brümmer J, Gutzki F, Berger J, Frölich J, Böger R
CIRCULATION. 2004;109(7):843-848.

Association of progesterone receptor polymorphism with recurrent abortions.
Schweikert A, Rau T, Berkholz A, Allera A, Daufeldt S, Wildt L
EUR J OBSTET GYN R B. 2004;113(1):67-72.

Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard.
Seeber S, Humeny A, Herkert M, Rau T, Eschenhagen T, Becker C
J BIOL CHEM. 2004;279(20):21062-21068.

[Beta blockers in cardiac insufficiency. When, how much and which substance]
Wuttke H, Rau T, Eschenhagen T
Med Monatsschr Pharm. 2004;27(12):412-415.

[Genetic polymorphisms in drug metabolizing enzymes--impact on treatment with beta-blockers]
Wuttke H, Rau T, Eschenhagen T
DEUT MED WOCHENSCHR. 2004;129(15):831-835.

Evidence for protein phosphatase inhibitor-1 playing an amplifier role in beta-adrenergic signaling in cardiac myocytes.
El-Armouche A, Rau T, Zolk O, Ditz D, Pamminger T, Zimmermann W, Jäckel E, Harding S, Boknik P, Neumann J, Eschenhagen T
FASEB J. 2003;17(3):437-439.

[Citalopram]
El-Armouche A, Zolk O, Eschenhagen T
DEUT MED WOCHENSCHR. 2003;128(43):2253-2256.

Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure.
El-Armouche A, Zolk O, Rau T, Eschenhagen T
CARDIOVASC RES. 2003;60(3):478-487.

Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography.
Hinz B, Auge D, Rau T, Rietbrock S, Brune K, Werner U
BIOMED CHROMATOGR. 2003;17(4):268-275.

Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.
Hinz B, Rau T, Auge D, Werner U, Ramer R, Rietbrock S, Brune K
CLIN PHARMACOL THER. 2003;74(3):222-235.

Antihypertensive therapy: special focus on drug interactions.
Maas R, Böger R
EXPERT OPIN DRUG SAF. 2003;2(6):549-579.

Old and new cardiovascular risk factors: from unresolved issues to new opportunities.
Maas R, Böger R
ATHEROSCLEROSIS PLUS. 2003;4(4):5-17.

Syncope, driving recommendations, and clinical reality: survey of patients.
Maas R, Ventura R, Kretzschmar C, Aydin M, Schuchert A
BMJ-BRIT MED J. 2003;326(7379):21.

Overexpression of wild-type Galpha(i)-2 suppresses beta-adrenergic signaling in cardiac myocytes.
Rau T, Nose M, Remmers U, Weil J, Weissmüller A, Davia K, Harding S, Peppel K, Koch W, Eschenhagen T
FASEB J. 2003;17(3):523-525.

Diagnostic yield of external electrocardiographic loop recorders in patients with recurrent syncope and negative tilt table test.
Schuchert A, Maas R, Kretzschmar C, Behrens G, Kratzmann I, Meinertz T
PACE. 2003;26(9):1837-1840.

Application of gas chromatography-mass spectrometry for analysis of isoprostanes: their role in cardiovascular disease.
Schwedhelm E, Böger R
CLIN CHEM LAB MED. 2003;41(12):1552-1561.

A crown venting technique for the cementation of implant-supported crowns.
Schwedhelm E, Lepe X, Aw T
J PROSTHET DENT. 2003;89(1):89-90.

Clinical pharmacokinetics of antioxidants and their impact on systemic oxidative stress.
Schwedhelm E, Maas R, Troost R, Böger R
CLIN PHARMACOKINET. 2003;42(5):437-459.

The mutagenic potentials of tap water samples in Shanghai.
Shen L, Wu J, Lin G, Shen J, Westendorf J, Huehnerfuss H
CHEMOSPHERE. 2003;52(9):1641-1646.

ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
Sydow K, Schwedhelm E, Arakawa N, Bode-Böger S, Tsikas D, Hornig B, Frölich J, Böger R
CARDIOVASC RES. 2003;57(1):244-252.

Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography-tandem mass spectrometry.
Tsikas D, Schwedhelm E, Stutzer F, Gutzki F, Iris R, Mehls C, Frölich J
J CHROMATOGR B. 2003;784(1):77-90.

Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF(2alpha). Possible methodological, mechanistic and clinical implications.
Tsikas D, Schwedhelm E, Suchy M, Niemann J, Gutzki F, Erpenbeck V, Hohlfeld J, Surdacki A, Frölich J
J CHROMATOGR B. 2003;794(2):237-255.

Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans.
Werner U, Werner D, Rau T, Fromm M, Hinz B, Brune K
CLIN PHARMACOL THER. 2003;74(2):130-137.

24-h Langendorff-perfused neonatal rat heart used to study the impact of adenoviral gene transfer.
Wiechert S, El-Armouche A, Rau T, Zimmermann W, Eschenhagen T
AM J PHYSIOL-HEART C. 2003;285(2):907-914.

Beta-adrenergic stimulation induces cardiac ankyrin repeat protein expression: involvement of protein kinase A and calmodulin-dependent kinase.
Zolk O, Marx M, Jäckel E, El-Armouche A, Eschenhagen T
CARDIOVASC RES. 2003;59(3):563-572.

Physiological antagonism between ventricular beta 1-adrenoceptors and alpha 1-adrenoceptors but no evidence for beta 2- and beta 3-adrenoceptor function in murine heart.
Heubach J, Rau T, Eschenhagen T, Ravens U, Kaumann A
BRIT J PHARMACOL. 2002;136(2):217-229.

Polyetheretherketone--cytotoxicity and mutagenicity in vitro.
Katzer A, Marquardt H, Westendorf J, Wening J, von Foerster G
BIOMATERIALS. 2002;23(8):1749-1759.

[Drug prescription studies. Goals and results]
Köhler G, Maas R
INTERNIST. 2002;43(4):511-515.

The pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function.
Maas R, Schwedhelm E, Albsmeier J, Böger R
VASC MED. 2002;7(3):213-225.

Effect of the CYP2D6 genotype on metoprolol metabolism persists during long-term treatment.
Rau T, Roland H, Bergmann K, Wuttke H, Werner U, Feifel N, Eschenhagen T
PHARMACOGENETICS. 2002;12(6):465-472.

Methodological considerations on the detection of 3-nitrotyrosine in the cardiovascular system.
Tsikas D, Schwedhelm E, Frölich J
CIRC RES. 2002;90(6):70.

A randomized and controlled pilot trial of beta-blockers for the treatment of recurrent syncope in patients with a positive or negative response to head-up tilt test.
Ventura R, Maas R, Zeidler D, Schoder V, Nienaber C, Schuchert A, Meinertz T
PACE. 2002;25(5):816-821.

Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects.
Wuttke H, Rau T, Roland H, Bergmann K, Böhm M, Weil J, Werner D, Eschenhagen T
CLIN PHARMACOL THER. 2002;72(4):429-437.

Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease.
Zoccali C, Benedetto F, Maas R, Mallamaci F, Tripepi G, Malatino L, Böger R
J AM SOC NEPHROL. 2002;13(2):490-496.

Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients.
Zoccali C, Mallamaci F, Maas R, Benedetto F, Tripepi G, Malatino L, Cataliotti A, Bellanuova I, Böger R
KIDNEY INT. 2002;62(1):339-345.

Activation of the cardiac endothelin system in left ventricular hypertrophy before onset of heart failure in TG(mREN2)27 rats.
Zolk O, Quattek J, Seeland U, El-Armouche A, Eschenhagen T, Böhm M
CARDIOVASC RES. 2002;53(2):363-371.

In vitro suppression of thymocyte apoptosis by metal-rich complex environmental mixtures: potential role of zinc and cadmium excess.
Chukhlovi A, Tokalov S, Yagunov A, Westendorf J, Reincke H, Karbe L
SCI TOTAL ENVIRON. 2001;281(1-3):153-163.

Constitutive expression and localization of COX-1 and COX-2 in rabbit iris and ciliary body.
Damm J, Rau T, Maihöfner C, Pahl A, Brune K
EXP EYE RES. 2001;72(6):611-621.

Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens.
Gutendorf B, Westendorf J
TOXICOLOGY. 2001;166(1-2):79-89.

Flurbiprofen enantiomers inhibit inducible nitric oxide synthase expression in RAW 264.7 macrophages.
Hinz B, Brune K, Rau T, Pahl A
PHARM RES-DORDR. 2001;18(2):151-156.

Prinzmetal angina documented by transtelephonic electrocardiographic monitoring.
Maas R, Brockhoff C, Patten-Hamel M, Meinertz T
CIRCULATION. 2001;103(22):2766.

[Emergencies in the practice. Hazards of "mix syringe"]
Münzel F, Eschenhagen T, Rau T, Zolk O
MMW Fortschr Med. 2001;143(44):44-47.

Fiber-type transitions and satellite cell activation in low-frequency-stimulated muscles of young and aging rats.
Putman C, Sultan K, Wassmer T, Bamford J, Skorjanc D, Pette D
J GERONTOL A-BIOL. 2001;56(12):510-519.

Toxicological profile of pollutants in surface water from an area in Taihu Lake, Yangtze Delta.
Shen J, Gutendorf B, Vahl H, Shen L, Westendorf J
TOXICOLOGY. 2001;166(1-2):71-78.

Fiber type-specific expression of major proteolytic systems in fast- to slow-transforming rabbit muscle.
Sultan K, Dittrich B, Leisner E, Paul N, Pette D
AM J PHYSIOL-CELL PH. 2001;280(2):239-247.

Psychiatric conditions in patients with recurrent unexplained syncope.
Ventura R, Maas R, Rüppel R, Stuhr U, Schuchert A, Meinertz T, Nienaber C
EUROPACE. 2001;3(4):311-316.

Muscle LIM protein is upregulated in fast skeletal muscle during transition toward slower phenotypes.
Willmann R, Kusch J, Sultan K, Schneider A, Pette D
AM J PHYSIOL-CELL PH. 2001;280(2):273-279.

[Drug interactions in the practice. Which combinations are taboo?]
Zolk O, El-Armouche A, Eschenhagen T
MMW Fortschr Med. 2001;143(51-52):24-32.

Normal oxidative stress and enhanced lipoprotein resistance to in vitro oxidation in hypertriglyceridemia: effects of bezafibrate therapy.
de Man F, Jonkers I, Schwedhelm E, Smelt A, Onkenhout W, VanDDuyvenvoorde W, Buytenhek R, Leuven J, Troost R, van Der Laarse A, Princen H
ARTERIOSCL THROM VAS. 2000;20(11):2434-2440.

Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift.
Doetze A, Satoguina J, Burchard G, Rau T, Löliger C, Fleischer B, Hoerauf A
INT IMMUNOL. 2000;12(5):623-630.

Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress.
Meyer F, Fiala E, Westendorf J
TOXICOLOGY. 2000;146(2-3):83-92.

Cell transformation and genotoxicity induced by bis(2, 3-dichloro-1-propyl) ether.
Neurath G, Martin F, Piasecki A, Ruge A, Cole K, Franke S, Francke W, Marquardt H
ENVIRON MOL MUTAGEN. 2000;35(4):312-318.

UDS induction by an array of standard carcinogens in human and rodent hepatocytes: effect of cryopreservation.
Schehrer L, Regan J, Westendorf J
TOXICOLOGY. 2000;147(3):177-191.

Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: a controlled study.
Schofer J, Schlüter M, Rau T, Hammer F, Haag N, Mathey D
J AM COLL CARDIOL. 2000;35(6):1554-1559.

Tandem mass spectrometric quantification of 8-iso-prostaglandin F2alpha and its metabolite 2,3-dinor-5,6-dihydro-8-iso-prostaglandin F2alpha in human urine.
Schwedhelm E, Tsikas D, Durand T, Gutzki F, Guy A, Rossi J, Frölich J
J CHROMATOGR B. 2000;744(1):99-112.

Transient expression of NMDA receptor subunit NR2B in the developing rat heart.
Seeber S, Becker K, Rau T, Eschenhagen T, Becker C, Herkert M
J NEUROCHEM. 2000;75(6):2472-2477.

Calpain activity in fast, slow, transforming, and regenerating skeletal muscles of rat.
Sultan K, Dittrich B, Pette D
AM J PHYSIOL-CELL PH. 2000;279(3):639-647.

Nebivolol decreases systemic oxidative stress in healthy volunteers.
Troost R, Schwedhelm E, Rojczyk S, Tsikas D, Frölich J
BRIT J CLIN PHARMACO. 2000;50(4):377-379.

Induction of DNA strand-breaks in primary rat hepatocytes by ginkgolic acids.
Westendorf J, Regan J
PHARMAZIE. 2000;55(11):864-865.

Pharmacological characterization of protein phosphatase activities in preparations from failing human hearts.
Neumann J, Maas R, Bokník P, Jones L, Zimmermann N, Scholz H
J PHARMACOL EXP THER. 1999;289(1):188-193.

Muscle LIM protein: expressed in slow muscle and induced in fast muscle by enhanced contractile activity.
Schneider A, Sultan K, Pette D
AM J PHYSIOL-HEART C. 1999;276(4 Pt 1):900-906.

Restenosis after stenting of matched occluded and non-occluded coronary arteries. Should there be a difference?
Schofer J, Rau T, Schlüter M, Mathey D
EUR HEART J. 1999;20(16):1175-1181.

Enhanced expression of CTLA-4 (CD152) on CD4+ T cells in HIV infection.
Steiner K, Waase I, Rau T, Dietrich M, Fleischer B, Bröker B
CLIN EXP IMMUNOL. 1999;115(3):451-457.

Time-dependent changes in myosin heavy chain mRNA and protein isoforms in unloaded soleus muscle of rat.
Stevens L, Sultan K, Peuker H, Gohlsch B, Mounier Y, Pette D
AM J PHYSIOL-HEART C. 1999;277(6 Pt 1):1044-1049.

Stenting of nonacute total coronary occlusions: predictors of late angiographic outcome.
Rau T, Schofer J, Schlüter M, Seidensticker A, Berger J, Mathey D
J AM COLL CARDIOL. 1998;31(2):275-280.

[Liver organ systems: valuation by gene expression]
Sultan K, Hartumg J, Bade Ernesto G
ALTEX-ALTERN TIEREXP. 1998;15(1):9-17.

Comparison of immediate and intermediate-term results of intravascular ultrasound versus angiography-guided Palmaz-Schatz stent implantation in matched lesions.
Albiero R, Rau T, Schlüter M, Di Mario C, Reimers B, Mathey D, Tobis J, Schofer J, Colombo A
CIRCULATION. 1997;96(9):2997-3005.

Uptake and metabolism of benzo(a)pyrene absorbed to sediment by the freshwater invertebrate species Chironomus riparius and Sphaerium corneum.
Borchert J, Karbe L, Westendorf J
B ENVIRON CONTAM TOX. 1997;58(1):158-165.

Short-term results and intermediate-term follow-up of laser wire recanalization of chronic coronary artery occlusions: a single-center experience.
Schofer J, Rau T, Schlüter M, Mathey D
J AM COLL CARDIOL. 1997;30(7):1722-1728.

Genotoxicity assessment of suspended particulate matter in the Elbe river: comparison of Salmonella microsome test, arabinose resistance test, and umu-test.
Vahl H, Karbe L, Westendorf J
MUTAT RES-FUND MOL M. 1997;394(1-3):81-93.

Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents.
Berger B, Marquardt H, Westendorf J
CANCER RES. 1996;56(9):2094-2104.

[Holiday heart syndrome]
Rau T, Mathey D
DEUT MED WOCHENSCHR. 1996;121(36):1108.

Recanalization of chronic coronary artery occlusions using laser followed by balloon angioplasty.
Schofer J, Kresser J, Rau T, Kunze K, Kühn C, Mathey D
AM J CARDIOL. 1996;78(7):836-838.

Hormone- and endotoxin-modulated gene expression of a long-term organ culture system of adult rat liver.
Sultan K, Hartung J, Bade E G
FEBS LETT. 1996;394(1):51-54.

Mechanisms of the contractile effects of 2,3-butanedione-monoxime in the mammalian heart.
Zimmermann N, Boknik P, Gams E, Gsell S, Jones L, Maas R, Neumann J, Scholz H
N-S ARCH PHARMACOL. 1996;354(4):431-436.

Decreased resistance to N,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells.
Schaefer A, Westendorf J, Lingelbach K, Schmidt C, Mihalache D, Reymann A, Marquardt H
CANCER CHEMOTH PHARM. 1993;31(4):301-307.

Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye.
Steinhorst U, Chen E, Hatchell D, Samsa G, Saloupis P, Westendorf J, Machemer R
INVEST OPHTH VIS SCI. 1993;34(5):1753-1760.

Formation of genotoxic metabolites from anthraquinone glycosides, present in Rubia tinctorum L.
Blömeke B, Poginsky B, Schmutte C, Marquardt H, Westendorf J
MUTAT RES-FUND MOL M. 1992;265(2):263-272.

Mutagenicity testing of imidazole and related compounds.
Forster R, Blowers S, Cinelli S, Marquardt H, Westendorf J
MUTAT RES-FUND MOL M. 1992;298(2):71-79.

Two-dimensional nuclear magnetic resonance studies of an intercalation complex between the novel semisynthetic anthracycline 3'-deamino-3'-(2-methoxy-4-morpholinyl)-doxorubicin and the hexanucleotide duplex d(CGTACG).
Odefey C, Westendorf J, Dieckmann T, Oschkinat H
CHEM-BIOL INTERACT. 1992;85(2-3):117-126.

Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L.
Poginsky B, Westendorf J, Blömeke B, Marquardt H, Hewer A, Grover P, Phillips D
CARCINOGENESIS. 1991;12(7):1265-1271.

Malignant transformation of mouse M2-fibroblasts by glycerol chlorohydrines contained in protein hydrolysates and commercial food.
Piasecki A, Ruge A, Marquardt H
ARZNEIMITTEL-FORSCH. 1990;40(9):1054-1055.

Genotoxicity of naturally occurring hydroxyanthraquinones.
Westendorf J, Marquardt H, Poginsky B, Dominiak M, Schmidt J
MUTAT RES-FUND MOL M. 1990;240(1):1-12.

Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes.
Wölfle D, Schmutte C, Westendorf J, Marquardt H
CANCER RES. 1990;50(20):6540-6544.

Proliferation of fetal rat hepatocytes in response to growth factors and hormones in primary culture.
Hoffmann B, Piasecki A, Paul D
J CELL PHYSIOL. 1989;139(3):654-662.

Mechanistic aspects of DNA damage by morpholinyl and cyanomorpholinyl anthracyclines.
Westendorf J, Aydin M, Groth G, Weller O, Marquardt H
CANCER RES. 1989;49(19):5262-5266.

Mutagenic and antimutagenic effects of 5-substituted 2'-deoxyuridines depending on the nature of the 5-substituent.
Marquardt H, Westendorf J, Schaefer A, Boldt J, De Clercq E
ARZNEIMITTEL-FORSCH. 1988;38(12):1820-1824.

Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes.
Paul D, Höhne M, Pinkert C, Piasecki A, Ummelmann E, Brinster R
EXP CELL RES. 1988;175(2):354-362.

Altered growth factor requirements and cell cycle control in rat hepatoma cells versus adult rat hepatocytes in culture.
Paul D, Piasecki A, Baisch H, Begemann M
EUR J CELL BIOL. 1988;46(2):270-274.

Inhibition of amino acid uptake and incorporation into proteins in Friend erythroleukemia cells by the anthracycline antitumor antibiotic aclacinomycin A.
Schaefer A, Boldt J, Westendorf J, Steinheider G, Marquardt H
BIOCHEM PHARMACOL. 1988;37(7):1377-1382.

Induction of erythroid differentiation by the anthracycline antitumor antibiotic pyrromycin.
Steinheider G, Schaefer A, Westendorf J, Marquardt H
CELL BIOL TOXICOL. 1988;4(1):123-133.

The genotoxicity of lucidin, a natural component of Rubia tinctorum L., and lucidinethylether, a component of ethanolic Rubia extracts.
Westendorf J, Poginsky B, Marquardt H, Groth G
CELL BIOL TOXICOL. 1988;4(2):225-239.

Possible carcinogenicity of anthraquinone-containing medical plants.
Westendorf J, Poginsky B, Marquardt H, Kraus L
PLANTA MED. 1988;54(6):562.

Transformation of differentiated neonatal rat hepatocytes in primary culture by polyoma virus early region sequences.
Höhne M, Piasecki A, Ummelmann E, Paul D
ONCOGENE. 1987;1(4):337-345.

Induction of chromosomal aberrations by the anthracycline antitumor antibiotics N,N-dimethyldaunomycin and aclacinomycin A.
Steinheider G, Westendorf J, Marquardt H
Experientia. 1987;43(5):586-588.

Induction of malignant transformation in vitro and mammary tumors in rats by two new potent anthracycline antitumor antibiotics, morpholinodaunomycin and cyanomorpholinoadriamycin.
Westendorf J, Mohr U, Marquardt H
CELL BIOL TOXICOL. 1987;3(1):17-21.

Induction of erythroid differentiation by the anthracycline antitumor antibiotics, aclacinomycin A, musettamycin and marcellomycin.
Steinheider G, Westendorf J, Marquardt H
LEUKEMIA RES. 1986;10(10):1233-1239.

DNA interaction and mutagenicity of the plastic stabilizer di-n-octyltin dichloride.
Westendorf J, Marquardt H
ARZNEIMITTEL-FORSCH. 1986;36(8):1263-1264.

Potent anti-viral 5-(2-bromovinyl) uracil nucleosides are inactive at inducing gene mutations in Salmonella typhimurium and V79 Chinese hamster cells and unscheduled DNA synthesis in primary rat hepatocytes.
Marquardt H, Westendorf J, De Clercq E
CARCINOGENESIS. 1985;6(8):1207-1209.

Formation of DNA-adducts and induction of DNA-crosslinks and chromosomal aberrations by the new potent anthracycline antitumor antibiotics: morpholinodaunomycin, cyanomorpholinodaunomycin and cyanomorpholinoadriamycin.
Westendorf J, Groth G, Steinheider G, Marquardt H
CELL BIOL TOXICOL. 1985;1(2):87-101.

Rat platelets contain growth factor(s) distinct from PDGF which stimulate DNA synthesis in primary adult rat hepatocyte cultures.
Paul D, Piasecki A
EXP CELL RES. 1984;154(1):95-100.

Structure-activity relationship of anthracycline-induced genotoxicity in vitro.
Westendorf J, Marquardt H
CANCER RES. 1984;44(12 Pt 1):5599-5604.

[Biotransformation of monolinuron (N-(4-chlorophenyl)-N'-methyl-N'methoxyurea) in isolated perfused chicken liver].
Westphal D, Lucas K, Hilbig V, Mechler U, Piasecki A
FOOD CHEM TOXICOL. 1984;22(7):521-528.

[Biliary excretion of choleretically active cinnamic acid derivatives in the rat]
Westendorf J, Czok G
Z Ernahrungswiss. 1983;22(4):255-270.

Tumorigenicity in vivo and induction of mutagenesis and DNA repair in vitro by aclacinomycin A and marcellomycin: structure-activity relationship and predictive value of short-term tests.
Westendorf J, Marquardt H, Ketkar M, Mohr U
CANCER RES. 1983;43(11):5248-5251.

Potent antiviral 2'-fluoro-arabinosyl pyrimidine nucleosides: lack of mutagenic activity.
Marquardt H, Westendorf J
CARCINOGENESIS. 1982;3(5):593-596.

[Spasmolytic and contractile effects of a combination product from plants on the smooth muscle of the guinea pigs]
Westendorf J, Vahlensieck W
ARZNEIMITTEL-FORSCH. 1981;31(1):40-43.

[Studies on the pharmacokinetics of C-14 cinnamic-acid derivatives in rats]
Westendorf J, Czok G
Z Ernahrungswiss. 1978;17(1):26-36.

[The salivary fluoride level after administration of fluorides and fluoride complex salts]
Knappwost A, Westendorf J, Hess J
DZZ - Deut Zahnärztl Z. 1977;32(6):487-489.

[Inhibition of acetylcholinesterase caused by fluoride]
Knappwost A, Westendorf J
SCI NAT-HEIDELBERG. 1974;61(6):274-275.

[Inhibition of cholinesterases caused by fluorine complex of silicon and of iron]
Knappwost A, Westendorf J
SCI NAT-HEIDELBERG. 1974;61(6):275.

[Fluorine ion incorporation and vagotonia. Inhibition of acetylcholinesterase using fluorine ions]
Knappwost A, Westendorf J
SCI NAT-HEIDELBERG. 1973;60(7):353-354.

Letzte Aktualisierung aus dem FIS: 24.04.2025 - 00:33 Uhr

Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients
Bartkowiak K, Mohammadi P, Nissen P, Werner S, Agorku D, Andreas A, Geffken M, Peine S, Verpoort K, Deutsch T, Michel L, Schneeweiss A, Thewes V, Trumpp A, Hardt O, Müller V, Riethdorf S, Schlüter H, Pantel K
SCI REP-UK. 2025;15(1):3913.

Lessons (to be) learned from liquid biopsies: assessment of circulating cells and cell-free DNA in cancer and pregnancy-acquired microchimerism
Bergmann L, Afflerbach A, Yuan T, Pantel K, Smit D
SEMIN IMMUNOPATHOL. 2025;47(1):14.

Identification and characterization of tumor and stromal derived liquid biopsy analytes in pancreatic ductal adenocarcinoma
Götze J, Meißner K, Pereira-Veiga T, Belloum Y, Schneegans S, Kropidlowski J, Gorgulho J, Busch A, Honselmann K, Schönrock M, Putscher A, Peine S, Nitschke C, Simon R, Spindler V, Izbicki J, Hackert T, Bokemeyer C, Pantel K, Uzunoglu F, Sinn M, Wikman H
J EXP CLIN CANC RES. 2025;44(1):14.

Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition
Melzer Y, Fergen N, Mess C, Stadler J, Geidel G, Schwietzer Y, Kött J, Pantel K, Schneider S, Utikal J, Wladykowski E, Vidal-Y-Sy S, Bauer A, Gebhardt C
TRANSL ONCOL. 2025;52:102224.

Breaking up clusters of circulating tumour cells to halt cancer spread
Smit D, Pantel K
NATURE. 2025;638(8050):329-330.

Incidental Findings of Maternal Cancer in Noninvasive Prenatal Testing through Cell-Free DNA Sequencing
Smit D, Pantel K
CLIN CHEM. 2025 [Epub ahead of print].

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model
Smit D, Pereira-Veiga T, Brauer H, Horn M, Nissen P, Mair T, Siebels B, Voß H, Zhuang R, Haider M, Loreth D, Iskhakova M, Lindemann B, Kött J, Cayrefourcq L, Wellbrock J, Schlüter H, Pantel K, Alix-Panabières C, Jücker M
MOL ONCOL. 2025 [Epub ahead of print].

Cancer-associated fibroblasts as a potential novel liquid biopsy marker in cancer patients
Weber F, Reese K, Pantel K, Smit D
J EXP CLIN CANC RES. 2025;44(1):.

Two decades of advances in clinical oncology - lessons learned and future directions
Banerjee S, Booth C, Bruera E, Büchler M, Drilon A, Fry T, Ghobrial I, Gianni L, Jain R, Kroemer G, Llovet J, Long G, Pantel K, Pritchard-Jones K, Scher H, Tabernero J, Weichselbaum R, Weller M, Wu Y
NAT REV CLIN ONCOL. 2024;21(11):771-780.

Expression profiling by high-throughput sequencing reveals GADD45, SMAD7, EGR-1 and HOXA3 activation in Myostatin (MSTN) and GDF11 treated myoblasts
Braun P, Alawi M, Saygi C, Pantel K, Wagers A
GENET MOL BIOL. 2024;47(2):e20230304.

Circulating Tumor Cells: From Basic to Translational Research
Cortés-Hernández L, Eslami-S Z, Pantel K, Alix-Panabières C
CLIN CHEM. 2024;70(1):81-89.

Relationship of Ki-67 index in biopsies of metastatic breast cancer tissue and circulating tumor cells (CTCs) at the time of biopsy collection
Deutsch T, Fischer C, Riedel F, Haßdenteufel K, Michel L, Sütterlin M, Riethdorf S, Pantel K, Wallwiener M, Schneeweiss A, Stefanovic S
ARCH GYNECOL OBSTET. 2024;309(1):235-248.

Efficacy of Lapatinib in Patients with HER2-Negative Metastatic Breast Cancer and HER2-Positive Circulating Tumor Cells-The DETECT III Clinical Trial
Fehm T, Mueller V, Banys-Paluchowski M, Fasching P, Friedl T, Hartkopf A, Huober J, Loehberg C, Rack B, Riethdorf S, Schneeweiss A, Wallwiener D, Meier-Stiegen F, Krawczyk N, Jaeger B, Reinhardt F, Hoffmann O, Mueller L, Wimberger P, Ruckhaeberle E, Blohmer J, Cieslik J, Franken A, Niederacher D, Neubauer H, Pantel K, Janni W
CLIN CHEM. 2024;70(1):307-318.

Differential predictive value of tissue-specific PD-L1 expression scores in adjuvant immunotherapy of melanoma
Geidel G, Parnian N, Meß C, Schlepper N, Rünger A, Heidrich I, Hansen I, Smit D, Menz A, Pantel K, Schneider S, Kött J, Gebhardt C
J EUR ACAD DERMATOL. 2024;38(10):2017-2023.

Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, Mertens H, Węglarz A, Sander S, Chojnowski G, Wikman H, Ohlenschläger O, von Amsberg G, Pantel K, Wilmanns M
NAT COMMUN. 2024;15(1):.

Liquid Biopsy – Ein neues diagnostisches Konzept in der Onkologie
Heidrich I, Roeper C, Rautmann C, Pantel K, Smit D
LARYNGO RHINO OTOL. 2024;103(1):40-46.

Detection of Multiple HPV Types in Liquid Biopsies of Cervical Neoplasia
Herbst J, Vohl V, Krajina M, Leffers M, Kropidlowski J, Prieske K, Jaeger A, Oliveira-Ferrer L, Schmalfeldt B, Goy Y, Burandt E, Pantel K, Vollmert C, Sartori A, Woelber L, Effenberger K, Wikman H
CLIN CHEM. 2024;70(1):285-296.

High Serum Levels of CCL20 Are Associated with Recurrence and Unfavorable Overall Survival in Advanced Melanoma Patients Receiving Immunotherapy
Kött J, Hoehne I, Heidrich I, Zimmermann N, Reese K, Zell T, Geidel G, Rünger A, Schneider S, Pantel K, Smit D, Gebhardt C
CANCERS. 2024;16(9):.

C-reactive protein flare predicts response to checkpoint inhibitor treatment in melanoma
Kött J, Zimmermann N, Zell T, Heidrich I, Geidel G, Rünger A, Smit D, Merkle M, Parnian N, Hansen I, Hoehne I, Abeck F, Torster L, Weichenthal M, Pantel K, Schneider S, Gebhardt C
J EUR ACAD DERMATOL. 2024;38(8):1575–1587.

KRAS and GNAS mutations in cell-free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms-an observational pilot study
Nitschke C, Tölle M, Walter P, Meißner K, Goetz M, Kropidlowski J, Berger A, Izbicki J, Nickel F, Hackert T, Pantel K, Wikman H, Uzunoglu F
MOL ONCOL. 2024 [Epub ahead of print].

EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma
Piper A, Penney C, Holliday J, Tincknell G, Ma Y, Napaki S, Pantel K, Brungs D, Ranson M
INT J MOL SCI. 2024;25(10):.

Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary
Pouyiourou M, Bochtler T, Coith C, Wikman H, Kraft B, Hielscher T, Stenzinger A, Riethdorf S, Pantel K, Krämer A
CLIN CHEM. 2024;70(1):297-306.

Multibiomarker panels in liquid biopsy for early detection of pancreatic cancer - a comprehensive review
Reese K, Pantel K, Smit D
J EXP CLIN CANC RES. 2024;43(1):.

Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells
Rieckmann L, Spohn M, Ruff L, Agorku D, Becker L, Borchers A, Krause J, O'Reilly R, Hille J, Velthaus-Rusik J, Beumer N, Günther A, Willnow L, Imbusch C, Iglauer P, Simon R, Franzenburg S, Winter H, Thomas M, Bokemeyer C, Gagliani N, Krebs C, Sprick M, Hardt O, Riethdorf S, Trumpp A, Stoecklein N, Peine S, Rosenstiel P, Pantel K, Loges S, Janning M
MOL CANCER. 2024;23(1):93.

Circulating Tumor Cells and Thromboembolic Events in Patients with Glioblastoma
Rolling C, Mohme M, Bokemeyer C, Westphal M, Riethdorf S, Lamszus K, Pantel K, Klingler F, Langer F
HAMOSTASEOLOGIE. 2024 [Epub ahead of print].

HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
Schneegans S, Löptien J, Mojzisch A, Loreth D, Kretz O, Raschdorf C, Hanssen A, Gocke A, Siebels B, Gunasekaran K, Ding Y, Oliveira-Ferrer L, Brylka L, Schinke T, Schlüter H, Paatero I, Voß H, Werner S, Pantel K, Wikman H
J EXP CLIN CANC RES. 2024;43(1):110.

Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma
Sementsov M, Ott L, Kött J, Sartori A, Lusque A, Degenhardt S, Segier B, Heidrich I, Volkmer B, Greinert R, Mohr P, Simon R, Stadler J, Irwin D, Koch C, Andreas A, Deitert B, Thewes V, Trumpp A, Schneeweiss A, Belloum Y, Peine S, Wikman H, Riethdorf S, Schneider S, Gebhardt C, Pantel K, Keller L
EMBO MOL MED. 2024;16(7):1560-1578.

Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells
Smit D, Brauer H, Horn S, Yigit G, Haider M, Pogenberg V, Schumacher U, Pantel K, Jücker M
CELL SIGNAL. 2024;121:.

Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension-to-Adherent Transition
Smit D, Hoffer K, Bettin B, Kriegs M, Cayrefourcq L, Schumacher U, Pantel K, Alix-Panabières C, Jücker M
CANCER MED-US. 2024;13(20):e70339.

Circulating tumor cells as liquid biopsy markers in cancer patients
Smit D, Pantel K
MOL ASPECTS MED. 2024;96:101258.

Clinical applications of circulating tumor cells in patients with solid tumors
Smit D, Schneegans-Murano S, Pantel K
CLIN EXP METASTAS. 2024;41(4):403-411.

Plasma ctDNA as a treatment response biomarker in metastatic cancers: evaluation by the RECIST working group
Wyatt A, Litière S, Bidard F, Cabel L, Dyrskjøt L, Karlovich C, Pantel K, Petrie J, Philip R, Andrews H, Vellanki P, Tolmeijer S, Villalobos Alberu X, Alfano C, Bogaerts J, Calvo E, Chen A, Toledo R, de Vries E, Seymour L, Laurie S, Garralda E
CLIN CANCER RES. 2024;30(22):5034-5041.

Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients
Abdo M, Belloum Y, Heigener D, Welker L, von Weihe S, Schmidt M, Heuer-Olewinski N, Watermann I, Szewczyk M, Kropidlowski J, Pereira-Veiga T, Elmas H, Perner S, Steurer S, Wikman H, Pantel K, Reck M
MOL ONCOL. 2023;17(5):737-746.

Detection and Isolation of Circulating Tumor Cells from Breast Cancer Patients Using CUB Domain-Containing Protein 1
Bartkowiak K, Mossahebi Mohammadi P, Gärtner S, Kwiatkowski M, Andreas A, Geffken M, Peine S, Verpoort K, Scholz U, Deutsch T, Michel L, Schneeweiss A, Thewes V, Trumpp A, Müller V, Riethdorf S, Schlüter H, Pantel K
J PROTEOME RES. 2023;22(4):1213-1230.

Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann L, Freytag V, Ahlers A, Maar H, Gosau T, Baranowsky A, Schmitz R, Pantel K, Schumacher U, Haider M, Lange T
BONE. 2023;171:116741.

Baseline CTC Count as a Predictor of Long-Term Outcomes in High-Risk Prostate Cancer
Cieślikowski W, Milecki P, Świerczewska M, Ida A, Kasperczak M, Jankowiak A, Nowicki M, Pantel K, Alix-Panabières C, Zabel M, Antczak A, Budna-Tukan J
J PERS MED. 2023;13(4):.

PSMA-heterogeneity in metastatic castration-resistant prostate cancer: Circulating tumor cells, metastatic tumor burden, and response to targeted radioligand therapy
Derlin T, Riethdorf S, Schumacher U, Lafos M, Peine S, Coith C, Ross T, Pantel K, Bengel F
PROSTATE. 2023;83(11):1076-1088.

Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value
Franken A, Kraemer A, Sicking A, Watolla M, Rivandi M, Yang L, Warfsmann J, Polzer B, Friedl T, Meier-Stiegen F, Stoecklein N, Dayan D, Riethdorf S, Mueller V, Pantel K, Koch A, Hartkopf A, Krawczyk N, Ruckhaeberle E, Niederacher D, Fehm T, Neubauer H
BRIT J CANCER. 2023;128(9):1742-1752.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors
Heidrich I, Deitert B, Werner S, Pantel K
CANCER METAST REV. 2023;42(1):161-182.

Liquid Biopsy  – Ein neues diagnostisches Konzept in der Onkologie
Heidrich I, Roeper C, Rautmann C, Pantel K, Smit D
DEUT MED WOCHENSCHR. 2023;148(10):597-604.

Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy
Hohmann N, Sprick M, Pohl M, Ahmed A, Burhenne J, Kirchner M, Le Cornet L, Kratzmann M, Hajda J, Stenzinger A, Steindorf K, Delorme S, Schlemmer H, Riethdorf S, van Schaik R, Pantel K, Siveke J, Seufferlein T, Jäger D, Haefeli W, Trumpp A, Springfeld C
CTS-CLIN TRANSL SCI. 2023;16(12):2483-2493.

Label Efficient Classification in Liquid Biopsy Data by Self-supervision
Husseini H, Nielsen M, Pantel K, Wikman H, Riethdorf S, Werner R
2023. Bildverarbeitung für die Medizin 2023. Deserno T, Handels H, Maier A, Maier-Hein K, Palm C, Tolxdorff T (Hrsg.). 1. Aufl. Springer Vieweg, 261-266.

EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma
Kocheise L, Schoenlein M, Behrends B, Joerg V, Casar C, Fründt T, Renné T, Heumann A, Li J, Huber S, Lohse A, Pantel K, Riethdorf S, Wege H, Schulze K, von Felden J
SCI REP-UK. 2023;13(1):20827.

Circulating tumour cells for early detection of clinically relevant cancer
Lawrence R, Watters M, Davies C, Pantel K, Lu Y
NAT REV CLIN ONCOL. 2023;20(7):487-500.

Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients
Leest P, Janning M, Rifaela N, Azpurua M, Kropidlowski J, Loges S, Lozano N, Sartori A, Irwin D, Lamy P, Hiltermann T, Groen H, Pantel K, Kempen L, Wikman H, Schuuring E
INT J MOL SCI. 2023;24(17):.

Five plus three for the pancreas
Löhr J, Pantel K
CLIN CANCER RES. 2023;29(8):1387-1389.

Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Walter P, Badbaran A, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Bardenhagen J, Stern L, Tintelnot J, Schönlein M, Sinn M, van der Leest P, Simon R, Heumann A, Izbicki J, Pantel K, Wikman H, Uzunoglu F
CLIN CHEM. 2023;69(3):295-307.

First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
Paschold L, Stein A, Thiele B, Tintelnot J, Henkes S, Coith C, Schultheiß C, Pantel K, Riethdorf S, Binder M
J IMMUNOTHER CANCER. 2023;11(6):.

RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, Dullin C, Rehling P, Glatzel M, Pantel K, Wikman H, Johnsen S, Gallwas J, Wegwitz F
CELL DEATH DIS. 2023;14(9):641.

Zirkulierende Tumorzellen
Reimers N, Pantel K
2023. Kompendium Internistische Onkologie. Schmoll H (Hrsg.). 5. Aufl. Berlin, Heidelberg: Springer, 1-7.

„Liquid biopsy“ – schon reif für Therapieentscheidungen?
Roeper C, Hoehne I, Schlepper N, Koch C, Pantel K, Smit D
best practice onkologie. 2023;18(5):194 - 202.

Experimental in vitro, ex vivo and in vivo models in prostate cancer research
Sailer V, von Amsberg G, Duensing S, Kirfel J, Lieb V, Metzger E, Offermann A, Pantel K, Schuele R, Taubert H, Wach S, Perner S, Werner S, Aigner A
NAT REV UROL. 2023;20(3):158-178.

Prognostic value of von Willebrand factor levels in patients with metastatic melanoma treated by immune checkpoint inhibitors
Stadler J, Keller L, Mess C, Bauer A, Koett J, Geidel G, Heidrich I, Vidal-Y-Sy S, Andreas A, Stramaglia C, Sementsov M, Haberstroh W, Deitert B, Hoehne I, Reschke R, Haalck T, Pantel K, Gebhardt C, Schneider S
J IMMUNOTHER CANCER. 2023;11(5):.

Preclinical models to study patient-derived circulating tumor cells and metastasis
Suvilesh K, Manjunath Y, Pantel K, Kaifi J
TRENDS CANCER. 2023;9(4):355-371.

A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer
Thomsen L, Honoré A, Reisæter L, Almås B, Børretzen A, Helle S, Førde K, Kristoffersen E, Kaada S, Melve G, Haslerud T, Biermann M, Bigalke I, Kvalheim G, Azeem W, Olsen J, Gabriel B, Knappskog S, Halvorsen O, Akslen L, Bahn D, Pantel K, Riethdorf S, Ragde H, Gjertsen B, Øyan A, Kalland K, Beisland C
CANCER IMMUNOL IMMUN. 2023;72(7):2357-2373.

Association Between Obesity and Circulating Tumor Cells in Early Breast Cancer Patients
Tzschaschel M, Friedl T, Schochter F, Schütze S, Polasik A, Fehm T, Pantel K, Schindlbeck C, Schneeweiss A, Schreier J, Tesch H, Lorenz R, Aivazova-Fuchs V, Häberle L, Fasching P, Janni W, Rack B, Fink V
CLIN BREAST CANCER. 2023;23(6):e345-e353.

Liquid Biopsy to Catch the Epigenetic Changes in Endometrial Cancer
Alix-Panabières C, Pantel K
CLIN CHEM. 2022;68(6):745-747.

Activated Eosinophils Predict Longer Progression-Free Survival under Immune Checkpoint Inhibition in Melanoma
Ammann N, Schwietzer Y, Mess C, Stadler J, Geidel G, Kött J, Pantel K, Schneider S, Utikal J, Bauer A, Gebhardt C
CANCERS. 2022;14(22):.

Circulating Cellular Communication Network Factor 1 Protein as a Sensitive Liquid Biopsy Marker for Early Detection of Breast Cancer
Bartkowiak K, Heidrich I, Kwiatkowski M, Banys-Paluchowski M, Andreas A, Wurlitzer M, Geffken M, Voß H, Zeller T, Blankenberg S, Peine S, Joosse S, Müller V, Schlüter H, Oliveira-Ferrer L, Pantel K
CLIN CHEM. 2022;68(2):344-353.

Interplay between coagulation and inflammation in cancer: Limitations and therapeutic opportunities
Bauer A, Gorzelanny C, Gebhardt C, Pantel K, Schneider S
CANCER TREAT REV. 2022;102:.

Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer
Besler K, Węglarz A, Keller L, von Amsberg G, Bednarz-Knoll N, Offermann A, Stoupiec S, Eltze E, Semjonow A, Boettcher L, Schneegans S, Perner S, Hauch S, Todenhöfer T, Peine S, Pantel K, Wikman H, Werner S
CLIN CHEM. 2022;68(7):973-983.

Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells
Brylka L, Jähn-Rickert K, Baranowsky A, Neven M, Horn M, Yorgan T, Wikman H, Werner S, Lübke A, Amling M, Busse B, Pantel K, Schinke T
CANCERS. 2022;14(3):.

With one eye on the future
Caldas C, Rescigno M, Turajlic S, Madabhushi A, Zhang Z, Lito P, Brown C, Pantel K, Haanen J, Duma N
CANCER CELL. 2022;40(3):221-225.

Possible tumour cell reimplantation during curative endoscopic therapy of superficial Barrett's carcinoma
Ehlken H, Schmitz R, Riethdorf S, Riethdorf L, Krause J, Karstens K, Schrader J, Viol F, Giannou A, Sterlacci W, Vieth M, Clauditz T, Kähler C, Mann O, Izbicki J, Huber S, Pantel K, Rösch T
GUT. 2022;71(2):277-286.

Regulation of bone homeostasis by MERTK and TYRO3
Engelmann J, Zarrer J, Gensch V, Riecken K, Berenbrok N, Luu T, Beitzen-Heineke A, Vargas-Delgado M, Pantel K, Bokemeyer C, Bhamidipati S, Darwish I, Masuda E, Burstyn-Cohen T, Alberto E, Ghosh S, Rothlin C, Hesse E, Taipaleenmäki H, Ben Batalla I, Loges S
NAT COMMUN. 2022;13(1):.

Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade
Eslami-S Z, Cortés-Hernández L, Thomas F, Pantel K, Alix-Panabières C
BRIT J CANCER. 2022;127(5):800-810.

Circulating tumor cells as a preoperative risk marker for occult metastases in patients with resectable cholangiocarcinoma
Fründt T, von Felden J, Krause J, Heumann A, Li J, Riethdorf S, Pantel K, Huber S, Lohse A, Wege H, Schulze K
FRONT ONCOL. 2022;12:.

Emerging precision diagnostics in advanced cutaneous squamous cell carcinoma
Geidel G, Heidrich I, Kött J, Schneider S, Pantel K, Gebhardt C
NPJ PRECIS ONCOL. 2022;6(1):.

Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation
Gerratana L, Pierga J, Reuben J, Davis A, Wehbe F, Dirix L, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Garcia-Saenz J, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, Bonotto M, Fernandez de Lascoiti A, De Mattos-Arruda L, Ignatiadis M, Sandri M, Generali D, De Angelis C, Dawson S, Janni W, Carañana V, Riethdorf S, Solomayer E, Puglisi F, Giuliano M, Pantel K, Bidard F, Cristofanilli M
ONCOLOGIST. 2022;27(7):e561-e570.

Tumor-Stroma Interaction in PDAC as a New Approach for Liquid Biopsy and its Potential Clinical Implications
Götze J, Nitschke C, Uzunoglu F, Pantel K, Sinn M, Wikman H
FRONT CELL DEV BIOL. 2022;10:.

Liquid biopsy: blood-based analyses of circulating cell-free DNA in xenografts
Heidrich I, Pantel K
EMBO MOL MED. 2022;14(8):.

Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions
Herbst J, Pantel K, Effenberger K, Wikman H
BRIT J CANCER. 2022;127(8):1403-1410.

Circulating DNA and Liquid Biopsies in the Management of Patients with Cancer
Joosse S, Pantel K
CANCER RES. 2022;82(12):2213-2215.

Detection of Hypomethylation in Long-ctDNA
Joosse S, Pantel K
CLIN CHEM. 2022;68(9):1115-1117.

Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo
Lange T, Valentiner U, Wicklein D, Maar H, Labitzky V, Ahlers A, Starzonek S, Genduso S, Staffeldt L, Pahlow C, Dück A, Stürken C, Baranowsky A, Bauer A, Bulk E, Schwab A, Riecken K, Börnchen C, Kiefmann R, Abraham V, DeLisser H, Gemoll T, Habermann J, Block A, Pantel K, Schumacher U
MOL THER. 2022;30(4):1536-1552.

Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
Leffers M, Herbst J, Kropidlowski J, Prieske K, Bohnen A, Peine S, Jaeger A, Prieske K, Goy Y, Schmalfeldt B, Pantel K, Wölber L, Effenberger K, Wikman H
CANCERS. 2022;14(16):.

Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels
Leong S, Naxerova K, Keller L, Pantel K, Witte M
CLIN EXP METASTAS. 2022;39(1):159-179.

Circulating Tumor-Macrophage Fusion Cells and Circulating Tumor Cells Complement Non-Small-Cell Lung Cancer Screening in Patients With Suspicious Lung-RADS 4 Nodules
Manjunath Y, Suvilesh K, Mitchem J, Avella Patino D, Kimchi E, Staveley-O'Carroll K, Pantel K, Yi H, Li G, Harris P, Chaudhuri A, Kaifi J
JCO PRECIS ONCOL. 2022;6:.

Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Merkens L, Sailer V, Lessel D, Janzen E, Greimeier S, Kirfel J, Perner S, Pantel K, Werner S, von Amsberg G
J EXP CLIN CANC RES. 2022;41(1):.

Detection and Characterization of Estrogen Receptor α Expression of Circulating Tumor Cells as a Prognostic Marker
Ningsi R, Elazezy M, Stegat L, Laakmann E, Peine S, Riethdorf S, Müller V, Pantel K, Joosse S
CANCERS. 2022;14(11):.

Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Konczalla L, Kropidlowski J, Pereira-Veiga T, Scognamiglio P, Schönrock M, Sinn M, Tölle M, Izbicki J, Pantel K, Uzunoglu F, Wikman H
BIOMEDICINES. 2022;10(11):.

Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
Nitschke C, Markmann B, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Schlüter H, Kwiatkowski M, Sinn M, Izbicki J, Pantel K, Güngör C, Uzunoglu F, Wikman H
CANCERS. 2022;14(18):.

Metastatic Breast Cancer Recurrence after Bone Fractures
Obi N, Werner S, Thelen F, Becher H, Pantel K
CANCERS. 2022;14(3):.

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation
Pantel K, Alix-Panabières C
J IMMUNOTHER CANCER. 2022;10(12):.

ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group
Pascual J, Attard G, Bidard F, Curigliano G, De Mattos-Arruda L, Diehn M, Italiano A, Lindberg J, Merker J, Montagut C, Normanno N, Pantel K, Pentheroudakis G, Popat S, Reis-Filho J, Tie J, Seoane J, Tarazona N, Yoshino T, Turner N
ANN ONCOL. 2022;33(8):750-768.

Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance
Pereira-Veiga T, Schneegans S, Pantel K, Wikman H
CELL REP. 2022;40(9):.

Characterization of immunologically detectable T-cell sensitization, Immunohistochemical detection of pro-inflammatory cytokines, and clinical parameters of patients after allogeneic intraoral bone grafting procedures: a prospective randomized controlled clinical trial in humans
Solakoglu Ö, Götz W, von Baehr V, Heydecke G, Pantel K, Schwarzenbach H
BMC ORAL HEALTH. 2022;22(1):.

Current and future clinical applications of ctDNA in immuno-oncology
Stadler J, Belloum Y, Deitert B, Sementsov M, Heidrich I, Gebhardt C, Keller L, Pantel K
CANCER RES. 2022;82(3):349-358.

Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses
Suvilesh K, Nussbaum Y, Radhakrishnan V, Manjunath Y, Avella D, Staveley-O'Carroll K, Kimchi E, Chaudhuri A, Shyu C, Li G, Pantel K, Warren W, Mitchem J, Kaifi J
MOL CANCER. 2022;21(1):.

Neoadjuvant Chemotherapy of Patients with Early Breast Cancer Is Associated with Increased Detection of Disseminated Tumor Cells in the Bone Marrow
Volmer L, Koch A, Matovina S, Dannehl D, Weiss M, Welker G, Hahn M, Engler T, Wallwiener M, Walter C, Oberlechner E, Brucker S, Pantel K, Hartkopf A
CANCERS. 2022;14(3):.

Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis
Wang Y, Liu X, Obser T, Bauer A, Heyes M, Starzonek S, Zulal M, Opitz K, Ott L, Riethdorf S, Lange T, Pantel K, Bendas G, Schneider S, Kusche-Gullberg M, Gorzelanny C
MATRIX BIOL. 2022;111:76-94.

Clinical management and biology of tumor dormancy in breast cancer
Werner S, Heidrich I, Pantel K
SEMIN CANCER BIOL. 2022;78:49-62.

Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
Westphal M, Pantel K, Ricklefs F, Maire C, Riethdorf S, Mohme M, Wikman H, Lamszus K
NEURO-ONCOL ADV. 2022;4(Suppl 2):ii45-ii52.

Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation
Woo H, Kim S, Kang H, Lee S, Lee S, Kim J, Gurel O, Kim S, Roh H, Lee J, Park Y, Shin H, Shin Y, Lee S, Oh S, Kim Y, Chae J, Lee S, Hong M, Cho B, Lee E, Pantel K, Kim H, Kim M
THERANOSTICS. 2022;12(8):3676-3689.

Evaluation of the Hamburg-Glasgow Classification in Pancreatic Cancer: Preoperative Staging by Combining Disseminated Tumor Load and Systemic Inflammation
Abdalla T, Almanfalouti V, Effenberger K, Uzunoglu F, Ghadban T, Dupreé A, Izbicki J, Pantel K, Reeh M
CANCERS. 2021;13(23):.

Prognostic value of preoperative circulating tumor cells counts in patients with UICC stage I-IV colorectal cancer
Abdalla T, Meiners J, Riethdorf S, König A, Melling N, Gorges T, Karstens K, Izbicki J, Pantel K, Reeh M
PLOS ONE. 2021;16(6):e0252897.

Blood-based detection of lung cancer using cysteine-rich angiogenic inducer 61 (CYR61) as a circulating protein biomarker: a pilot study
Ac Kar L, Casjens S, Andreas A, Raiko I, Brüning T, Geffken M, Peine S, Kollmeier J, Johnen G, Bartkowiak K, Weber D, Pantel K
MOL ONCOL. 2021;15(11):2877-2890.

Liquid Biopsy: From Discovery to Clinical Application
Alix-Panabières C, Pantel K
CANCER DISCOV. 2021;11(4):858-873.

Liquid biopsy: from discovery to clinical implementation
Alix-Panabières C, Pantel K
MOL ONCOL. 2021;15(6):1617-1621.

ViBiBa: Virtual BioBanking for the DETECT multicenter trial program - decentralized storage and processing
Asperger H, Cieslik J, Alberter B, Köstler C, Polzer B, Müller V, Pantel K, Riethdorf S, Koch A, Hartkopf A, Wiesmüller L, Janni W, Schochter F, Franken A, Niederacher D, Fehm T, Neubauer H
TRANSL ONCOL. 2021;14(8):101132.

Sensitive Blood-Based Detection of Asbestos-Associated Diseases Using Cysteine-Rich Angiogenic Inducer 61 as Circulating Protein Biomarker
Bartkowiak K, Casjens S, Andreas A, Ačkar L, Joosse S, Raiko I, Brüning T, Geffken M, Peine S, Johnen G, Weber D, Pantel K
CLIN CHEM. 2021;67(2):363-373.

Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells
Bartkowiak K, Heidrich I, Kwiatkowski M, Gorges T, Andreas A, Geffken M, Verpoort K, Müller V, Schlüter H, Pantel K
CANCERS. 2021;13(3):.

AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms
Beitzen-Heineke A, Berenbrok N, Waizenegger J, Päsler S, Gensch V, Udonta F, Vargas-Delgado M, Engelmann J, Hoffmann F, Schafhausen P, von Amsberg G, Riecken K, Beumer N, Imbusch C, Lorens J, Fischer T, Pantel K, Bokemeyer C, Ben Batalla I, Loges S
HEMASPHERE. 2021;5(9):.

BRCA1 promoter hypermethylation on circulating tumor DNA correlates with improved survival of patients with ovarian cancer
Elazezy M, Prieske K, Kluwe L, Oliveira-Ferrer L, Peine S, Müller V, Woelber L, Schmalfeldt B, Pantel K, Joosse S
MOL ONCOL. 2021;15(12):3615-3625.

Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer
Elazezy M, Schwentesius S, Stegat L, Wikman H, Werner S, Mansour W, Failla A, Peine S, Müller V, Thiery J, Ebrahimi Warkiani M, Pantel K, Joosse S
CANCERS. 2021;13(15):.

Disseminated tumour cells from the bone marrow of early breast cancer patients: Results from an international pooled analysis
Hartkopf A, Brucker S, Taran F, Harbeck N, von Au A, Naume B, Pierga J, Hoffmann O, Beckmann M, Rydén L, Fehm T, Aft R, Solà M, Walter V, Rack B, Schuetz F, Borgen E, Ta M, Bittner A, Fasching P, Fernö M, Krawczyk N, Weilbaecher K, Margelí M, Hahn M, Jueckstock J, Domschke C, Bidard F, Kasimir-Bauer S, Schoenfisch B, Kurt A, Wallwiener M, Gebauer G, Klein C, Wallwiener D, Janni W, Pantel K
EUR J CANCER. 2021;154:128-137.

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as a Liquid Biopsy Marker in Colorectal Cancer
Heidrich I, Abdalla T, Reeh M, Pantel K
CANCERS. 2021;13(18):.

Liquid biopsies: Potential and challenges
Heidrich I, Ačkar L, Mossahebi Mohammadi P, Pantel K
INT J CANCER. 2021;148(3):528-545.

Novel approaches to target the microenvironment of bone metastasis
Hofbauer L, Bozec A, Rauner M, Jakob F, Perner S, Pantel K
NAT REV CLIN ONCOL. 2021;18(8):488-505.

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Keller L, Belloum Y, Wikman H, Pantel K
BRIT J CANCER. 2021;124(2):345-358.

Possible Role of Circulating Tumour Cells for Prediction of Salvage Lymph Node Dissection Outcome in Patients with Early Prostate Cancer Recurrence
Knipper S, Riethdorf S, Werner S, Tilki D, Graefen M, Pantel K, Maurer T
EUR UROL OPEN SCI. 2021;34:55-58.

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse S, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider S, Belczacka I, Volkmer B, Greinert R, Yaspo M, Harter P, Pantel K, Wikman H
INT J MOL SCI. 2021;22(13):.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Enumeration and Changes in Circulating Tumor Cells and Their Prognostic Value in Patients Undergoing Cytoreductive Radical Prostatectomy for Oligometastatic Prostate Cancer-Translational Research Results from the Prospective ProMPT trial
Mandel P, Huland H, Tiebel A, Haese A, Salomon G, Budäus L, Tilki D, Chun F, Heinzer H, Graefen M, Pantel K, Riethdorf S, Steuber T
EUR UROL FOCUS. 2021;7(1):55-62.

Decreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments
Mieczkowska I, Pantelaiou-Prokaki G, Prokakis E, Schmidt G, Müller-Kirschbaum L, Werner M, Sen M, Velychko T, Jannasch K, Dullin C, Napp J, Pantel K, Wikman H, Wiese M, Kramm C, Alves F, Wegwitz F
CELL DEATH DIS. 2021;12(12):.

Prognostic relevance of the HER2 status of circulating tumor cells in metastatic breast cancer patients screened for participation in the DETECT study program
Müller V, Banys-Paluchowski M, Friedl T, Fasching P, Schneeweiss A, Hartkopf A, Wallwiener D, Rack B, Meier-Stiegen F, Huober J, Rübner M, Hoffmann O, Müller L, Janni W, Wimberger P, Jäger B, Pantel K, Riethdorf S, Harbeck N, Fehm T
ESMO OPEN. 2021;6(6):.

Detection of Circulating Tumor Cells (CTCs) in Patients with Testicular Germ Cell Tumors
Nastały P, Honecker F, Pantel K, Riethdorf S
Methods Mol Biol. 2021;2195:245-261.

Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID
Neves R, Ammerlaan W, Andree K, Bender S, Cayrefourcq L, Driemel C, Koch C, Luetke-Eversloh M, Oulhen M, Rossi E, Alix-Panabières C, Betsou F, Farace F, Riethdorf S, Schlange T, Wikman H, Zamarchi R, Pantel K, Terstappen L, Stoecklein N
CLIN CHEM. 2021;67(4):631-641.

Analysis of tripartite motif (TRIM) family gene expression in prostate cancer bone metastases
Offermann A, Kang D, Watermann C, Weingart A, Hupe M, Saraji A, Stegmann-Frehse J, Kruper R, Schüle R, Pantel K, Taubert H, Duensing S, Culig Z, Aigner A, Klapper W, Jonigk D, Philipp Kühnel M, Merseburger A, Kirfel J, Sailer V, Perner S
CARCINOGENESIS. 2021;42(12):1475-1484.

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions
Pantano F, Croset M, Driouch K, Bednarz-Knoll N, Iuliani M, Ribelli G, Bonnelye E, Wikman H, Geraci S, Bonin F, Simonetti S, Vincenzi B, Hong S, Sousa S, Pantel K, Tonini G, Santini D, Clézardin P
ONCOGENE. 2021;40(7):1284-1299.

Liquid Biopsy: Blood-Based Analyses of ctDNA and CTCs
Pantel K
CLIN CHEM. 2021;67(11):1437-1439.

High Serum Levels of Wnt Signaling Antagonist Dickkopf-Related Protein 1 Are Associated with Impaired Overall Survival and Recurrence in Esophageal Cancer Patients
Ramirez J, Smit D, Viol F, Schrader J, Ghadban T, Pantel K, Izbicki J, Reeh M
CANCERS. 2021;13(19):.

Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain
Robador J, Feinauer M, Schneider S, Mayer F, Gorzelanny C, Sacharow A, Liu X, Berghoff A, Brehm M, Hirsch D, Stadler J, Vidal-Y-Si S, Wladykowski E, Asong M, Nowak K, Seiz-Rosenhagen M, Umansky V, Mess C, Pantel K, Winkler F, Bauer A
NEURO-ONCOL ADV. 2021;3(1):.

Functional Characterization of Circulating Tumor Cells (CTCs) from Metastatic ER+/HER2- Breast Cancer Reveals Dependence on HER2 and FOXM1 for Endocrine Therapy Resistance and Tumor Cell Survival: Implications for Treatment of ER+/HER2- Breast Cancer
Roßwag S, Cotarelo C, Pantel K, Riethdorf S, Sleeman J, Schmidt M, Thaler S
CANCERS. 2021;13(8):.

Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy
Smit D, Pantel K, Jücker M
BIOCHEM PHARMACOL. 2021;188:114589.

A Comprehensive Molecular Analysis of in Vivo Isolated EpCAM-Positive Circulating Tumor Cells in Breast Cancer
Strati A, Zavridou M, Kallergi G, Politaki E, Kuske A, Gorges T, Riethdorf S, Joosse S, Koch C, Bohnen A, Mueller V, Koutsodontis G, Kontopodis E, Poulakaki N, Psyrri A, Mavroudis D, Georgoulias V, Pantel K, Lianidou E
CLIN CHEM. 2021;67(10):1395-1405.

Circulating DNA and other biomarker for early diagnosis: Great potential, but challenges recognized
Babayan A, Reimers N, Pantel K
2020. World Cancer Report. Wild C, Weiderpass E, Stewart B (Hrsg.). 1. Aufl. Lyon: World Health Organization, 550 -556.

In Vitro Modeling of Reoxygenation Effects on mRNA and Protein Levels in Hypoxic Tumor Cells upon Entry into the Bloodstream
Bartkowiak K, Koch C, Gärtner S, Andreas A, Gorges T, Pantel K
CELLS-BASEL. 2020;9(5):.

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
Belloum Y, Janning M, Mohme M, Simon R, Kropidlowski J, Sartori A, Irwin D, Westphal M, Lamszus K, Loges S, Riethdorf S, Pantel K, Wikman H
CELLS-BASEL. 2020;9(11):.

Evaluation of PD-L1 expression on circulating tumor cells (CTCs) in patients with advanced urothelial carcinoma (UC)
Bergmann S, Coym A, Ott L, Soave A, Rink M, Janning M, Stoupiec M, Coith C, Peine S, von Amsberg G, Pantel K, Riethdorf S
ONCOIMMUNOLOGY. 2020;9(1):.

HER2-targeted therapy influences CTC status in metastatic breast cancer
Deutsch T, Riethdorf S, Fremd C, Feisst M, Nees J, Fischer C, Hartkopf A, Pantel K, Trumpp A, Schütz F, Schneeweiss A, Wallwiener M
BREAST CANCER RES TR. 2020;182(1):127-136.

Rationale and Design of the Hamburg City Health Study
Jagodzinski A, Johansen C, Koch-Gromus U, Aarabi G, Adam G, Anders S, Augustin M, der Kellen R, Beikler T, Behrendt C, Betz C, Bokemeyer C, Borof K, Briken P, Busch C, Büchel C, Brassen S, Debus E, Eggers L, Fiehler J, Gallinat J, Gellißen S, Gerloff C, Girdauskas E, Gosau M, Graefen M, Härter M, Harth V, Heidemann C, Heydecke G, Huber T, Hussein Y, Kampf M, von dem Knesebeck O, Konnopka A, König H, Kromer R, Kubisch C, Kühn S, Loges S, Löwe B, Lund G, Meyer C, Nagel L, Nienhaus A, Pantel K, Petersen E, Püschel K, Reichenspurner H, Sauter G, Scherer M, Scherschel K, Schiffner U, Schnabel R, Schulz H, Smeets R, Sokalskis V, Spitzer M, Terschüren C, Thederan I, Thoma T, Thomalla G, Waschki B, Wegscheider K, Wenzel J, Wiese S, Zyriax B, Zeller T, Blankenberg S
EUR J EPIDEMIOL. 2020;35(2):169-181.

Tumor-Associated Release of Prostatic Cells into the Blood after Transrectal Ultrasound-Guided Biopsy in Patients with Histologically Confirmed Prostate Cancer
Joosse S, Beyer B, Gasch C, Nastały P, Kuske A, Isbarn H, Horst L, Hille C, Gorges T, Cayrefourcq L, Alix-Panabières C, Tennstedt P, Riethdorf S, Schlomm T, Pantel K
CLIN CHEM. 2020;66(1):161-168.

Lymph Node and Bone Marrow Micrometastases Define the Prognosis of Patients with pN0 Esophageal Cancer
Karstens K, Ghadban T, Effenberger K, Sauter G, Pantel K, Izbicki J, Vashist Y, König A, Reeh M
CANCERS. 2020;12(3):588.

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity
Koch C, Kuske A, Joosse S, Yigit G, Sflomos G, Thaler S, Smit D, Werner S, Borgmann K, Gärtner S, Mossahebi Mohammadi P, Battista L, Cayrefourcq L, Altmüller J, Salinas-Riester G, Raithatha K, Zibat A, Goy Y, Ott L, Bartkowiak K, Tan T, Zhou Q, Speicher M, Müller V, Gorges T, Jücker M, Thiery J, Brisken C, Riethdorf S, Alix-Panabières C, Pantel K
EMBO MOL MED. 2020;12(9):.

Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
Lampignano R, Neumann M, Weber S, Kloten V, Herdean A, Voss T, Groelz D, Babayan A, Tibbesma M, Schlumpberger M, Chemi F, Rothwell D, Wikman H, Galizzi J, Bergheim I, Russnes H, Mussolin B, Bonin S, Voigt C, Musa H, Pinzani P, Lianidou E, Brady G, Speicher M, Pantel K, Betsou F, Schuuring E, Kubista M, Ammerlaan W, Sprenger-Haussels M, Schlange T, Heitzer E
CLIN CHEM. 2020;66(1):149-160.

Author Correction: Intraoperative detection of circulating tumor cells in pulmonary venous blood during metastasectomy for colorectal lung metastases
Le U, Bronsert P, Picardo F, Riethdorf S, Haager B, Rylski B, Czerny M, Beyersdorf F, Wiesemann S, Pantel K, Passlick B, Kaifi J, Schmid S
SCI REP-UK. 2020;10(1):7633.

Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform
Liu H, Koch C, Haller A, Joosse S, Kumar R, Vellekoop M, Horst L, Keller L, Babayan A, Failla A, Jensen J, Peine S, Keplinger F, Fuchs H, Pantel K, Hirtz M
ADV BIOSYST. 2020;4(2):e1900162.

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Mohme M, Maire C, Schliffke S, Joosse S, Alawi M, Matschke J, Schüller U, Dierlamm J, Martens T, Pantel K, Riethdorf S, Lamszus K, Westphal M
ACTA NEUROPATHOL COM. 2020;8(1):.

ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg J, Loreth D, Brylka L, Werner S, Karbanova J, Gandrass M, Schneegans S, Besler K, Hamester F, Robador J, Bauer A, Werner Schneider S, Wrage M, Lamszus K, Matschke J, Vashist Y, Uzunoglu G, Steurer S, Horst A, Oliveira-Ferrer L, Glatzel M, Schinke T, Corbeil D, Pantel K, Maire C, Wikman H
NEURO-ONCOLOGY. 2020;22(7):955-966.

The Impact of Circulating Tumor Cells on Venous Thromboembolism and Cardiovascular Events in Bladder Cancer Patients Treated with Radical Cystectomy
Rink M, Riethdorf S, Yu H, Kölker M, Vetterlein M, Dahlem R, Fisch M, Pantel K, Soave A
J CLIN MED. 2020;9(11):.

Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients
Schneegans S, Lück L, Besler K, Bluhm L, Stadler J, Staub J, Greinert R, Volkmer B, Kubista M, Gebhardt C, Sartori A, Irwin D, Serkkola E, Af Hällström T, Lianidou E, Sprenger-Haussels M, Hussong M, Mohr P, Schneider S, Shaffer J, Pantel K, Wikman H
MOL ONCOL. 2020;14(5):1001-1015.

High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors
Smit D, Cayrefourcq L, Haider M, Hinz N, Pantel K, Alix-Panabières C, Jücker M
CELLS-BASEL. 2020;9(9):.

Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy
Soave A, Kluwe L, Yu H, Rink M, Gild P, Vetterlein M, Marks P, Sauter G, Fisch M, Meyer C, Ludwig T, Dahlem R, Minner S, Pantel K, Steinbach B, Schwarzenbach H
SCI REP-UK. 2020;10(1):21562.

The Lack of Evidence for an Association between Cancer Biomarker Conversion Patterns and CTC-Status in Patients with Metastatic Breast Cancer
Stefanovic S, Deutsch T, Riethdorf S, Fischer C, Hartkopf A, Sinn P, Feisst M, Pantel K, Golatta M, Brucker S, Sütterlin M, Schneeweiss A, Wallwiener M
INT J MOL SCI. 2020;21(6):.

Correction: Role of growth arrest-specific gene 6-mer axis in multiple myeloma
Waizenegger J, Ben-Batalla I, Weinhold N, Meissner T, Wroblewski M, Janning M, Riecken K, Binder M, Atanackovic D, Taipaleenmaeki H, Schewe D, Sawall S, Gensch V, Cubas-Cordova M, Seckinger A, Atanackovic D, Hesse E, Kröger N, Fehse B, Hose D, Klein B, Raab M, Pantel K, Bokemeyer C, Loges S
LEUKEMIA. 2020;34(9):2542.

Clinical Relevance of Circulating Tumor Cells in Esophageal Cancer Detected by a Combined MACS Enrichment Method
Woestemeier A, Harms-Effenberger K, Karstens K, Konczalla L, Ghadban T, Uzunoglu F, Izbicki J, Bockhorn M, Pantel K, Reeh M
CANCERS. 2020;12(3):718.

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Aktas B, Fasching P, Hartkopf A, Janni W, Kasimir-Bauer S, Pantel K, Schön G, Rack B, Riethdorf S, Solomayer E, Fehm T, Müller V
SCI REP-UK. 2019;9(1):2318.

Analysis of Circulating Tumor Cells in Patients with Non-Metastatic High-Risk Prostate Cancer before and after Radiotherapy Using Three Different Enumeration Assays
Budna-Tukan J, Świerczewska M, Mazel M, Cieślikowski W, Ida A, Jankowiak A, Antczak A, Nowicki M, Pantel K, Azria D, Zabel M, Alix-Panabières C
CANCERS. 2019;11(6):.

In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy
Chen S, Tauber G, Langsenlehner T, Schmölzer L, Pötscher M, Riethdorf S, Kuske A, Leitinger G, Kashofer K, Czyż Z, Polzer B, Pantel K, Sedlmayr P, Kroneis T, El-Heliebi A
CANCERS. 2019;11(7):.

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
Cristofanilli M, Pierga J, Reuben J, Rademaker A, Davis A, Peeters D, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Giuliano M, Garcia-Saenz J, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, de Lascoiti A, De Mattos-Arruda L, Ignatiadis M, Cabel L, van Laere S, Meier-Stiegen F, Sandri M, Vidal-Martinez J, Politaki E, Consoli F, Generali D, Cappelletti M, Diaz-Rubio E, Krell J, Dawson S, Raimondi C, Rutten A, Janni W, Munzone E, Carañana V, Agelaki S, Almici C, Dirix L, Solomayer E, Zorzino L, Darrigues L, Reis-Filho J, Gerratana L, Michiels S, Bidard F, Pantel K
CRIT REV ONCOL HEMAT. 2019;134:39-45.

Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients
Gorges K, Wiltfang L, Gorges T, Sartori A, Hildebrandt L, Keller L, Volkmer B, Peine S, Babayan A, Moll I, Schneider S, Twarock S, Mohr P, Fischer J, Pantel K
CANCERS. 2019;11(11):1685.

Detection of Androgen Receptor Variant 7 (ARV7) mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer
Hille C, Gorges T, Riethdorf S, Mazel M, Steuber T, Amsberg G, König F, Peine S, Alix-Panabières C, Pantel K
CELLS-BASEL. 2019;8(9):.

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
Janning M, Kobus F, Babayan A, Wikman H, Velthaus J, Bergmann S, Schatz S, Falk M, Berger L, Böttcher L, Päsler S, Gorges T, O'Flaherty L, Hille C, Joosse S, Simon R, Tiemann M, Bokemeyer C, Reck M, Riethdorf S, Pantel K, Loges S
CANCERS. 2019;11(6):.

Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer
Jauch S, Riethdorf S, Sprick M, Schütz F, Schönfisch B, Brucker S, Deutsch T, Nees J, Saini M, Becker L, Burwinkel B, Sinn P, Marmé F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A
BREAST CANCER RES TR. 2019;173(1):155-165.

Biology and clinical relevance of EpCAM
Keller L, Werner S, Pantel K
CELL STRESS. 2019;3(6):165-180.

Prospective Comparison of the Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of a Single Patient's Cohort With Esophageal Cancer
Konczalla L, Ghadban T, Effenberger K, Wöstemeier A, Riethdorf S, Uzunoglu F, Izbicki J, Pantel K, Bockhorn M, Reeh M
ANN SURG. 2019;273(2):299-305.

Liquid Biopsies
Lianidou E, Pantel K
GENE CHROMOSOME CANC. 2019;58(4):219-232.

EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer
Lindsay C, Blackhall F, Carmel A, Fernandez-Gutierrez F, Gazzaniga P, Groen H, Hiltermann T, Krebs M, Loges S, López-López R, Muinelo-Romay L, Pantel K, Priest L, Riethdorf S, Rossi E, Terstappen L, Wikman H, Soria J, Farace F, Renehan A, Dive C, Besse B, Michiels S
EUR J CANCER. 2019;117:60-68.

ALDH1-positive intratumoral stromal cells indicate differentiated epithelial-like phenotype and good prognosis in prostate cancer
Nastały P, Filipska M, Morrissey C, Eltze E, Semjonow A, Brandt B, Pantel K, Bednarz-Knoll N
TRANSL RES. 2019;203:49-56.

Somatic aberrations of BRCA1 gene are associated with ALDH1, EGFR, and tumor progression in prostate cancer
Omari A, Nastały P, Stoupiec S, Bałabas A, Dąbrowska M, Bielińska B, Huss S, Pantel K, Semjonow A, Eltze E, Brandt B, Bednarz-Knoll N
INT J CANCER. 2019;144(3):607-614.

Liquid biopsy and minimal residual disease - latest advances and implications for cure
Pantel K, Alix-Panabières C
NAT REV CLIN ONCOL. 2019;16(7):409-424.

Circulating Tumor Cells in Prostate Cancer: From Discovery to Clinical Utility
Pantel K, Hille C, Scher H
CLIN CHEM. 2019;65(1):87-99.

Möglichkeiten und Grenzen von Liquid Biopsy
Pantel K, Reimers N
Osteoporose, Orthopädie &Rheuma aktuell. 2019;2019(4):.

Liquid biopsy: novel technologies and clinical applications
Reimers N, Pantel K
CLIN CHEM LAB MED. 2019;57(3):312-316.

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs F, Maire C, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland D, Flitsch J, Martens T, Schmidt N, Peine S, Breakefield X, Lawler S, Chiocca E, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K
J EXTRACELL VESICLES. 2019;8(1):1588555.

Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H
BREAST CANCER RES. 2019;21(1):101.

Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma
Riethdorf S, Hildebrandt L, Heinzerling L, Heitzer E, Fischer N, Bergmann S, Mauermann O, Waldispühl-Geigl J, Coith C, Schön G, Peine S, Schuler G, Speicher M, Moll I, Pantel K
CLIN CHEM. 2019;65(3):462-472.

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.

Presence of Circulating Tumor Cells in High-Risk Early Breast Cancer During Follow-Up and Prognosis
Trapp E, Janni W, Schindlbeck C, Jückstock J, Andergassen U, de Gregorio A, Alunni-Fabbroni M, Tzschaschel M, Polasik A, Koch J, Friedl T, Fasching P, Haeberle L, Fehm T, Schneeweiss A, Beckmann M, Pantel K, Mueller V, Rack B, Scholz C
JNCI-J NATL CANCER I. 2019;111(4):380-387.

11th International Symposium on Minimal Residual Cancer (ISMRC): 3-5 May 2018, Montpellier, France
Alix-Panabières C, Pantel K
CLIN EXP METASTAS. 2018;35(3):87-90.

Abstracts from the 11th International Symposium on Minimal Residual Disease, 3-5 May 2018, Montpellier, France
Alix-Panabières C, Pantel K
CLIN EXP METASTAS. 2018;35(3):167-217.

Clinical utility of circulating non-coding RNAs - an update
Anfossi S, Babayan A, Pantel K, Calin G
NAT REV CLIN ONCOL. 2018;15(9):541-563.

Advances in liquid biopsy approaches for early detection and monitoring of cancer
Babayan A, Pantel K
GENOME MED. 2018;10(1):21.

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany
Bailey D, Pichler B, Gückel B, Antoch G, Barthel H, Bhujwalla Z, Biskup S, Biswal S, Bitzer M, Boellaard R, Braren R, Brendle C, Brindle K, Chiti A, la Fougère C, Gillies R, Goh V, Goyen M, Hacker M, Heukamp L, Knudsen G, Krackhardt A, Law I, Morris J, Nikolaou K, Nuyts J, Ordonez A, Pantel K, Quick H, Riklund K, Sabri O, Sattler B, Troost E, Zaiss M, Zender L, Beyer T
MOL IMAGING BIOL. 2018;20(1):4-20.

Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer
Banys-Paluchowski M, Fehm T, Janni W, Aktas B, Fasching P, Kasimir-Bauer S, Milde-Langosch K, Pantel K, Rack B, Riethdorf S, Solomayer E, Witzel I, Müller V
BMC CANCER. 2018;18(1):541.

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
Banys-Paluchowski M, Fehm T, Witzel I, Aktas B, Fasching P, Hartkopf A, Janni W, Kasimir-Bauer S, Pantel K, Schön G, Rack B, Riethdorf S, Solomayer E, Müller V
GEBURTSH FRAUENHEILK. 2018;78(11):1151.

The clinical relevance of serum vascular endothelial growth factor (VEGF) in correlation to circulating tumor cells and other serum biomarkers in patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Riethdorf S, Pantel K, Rack B, Janni W, Fasching P, Aktas B, Kasimir-Bauer S, Hartkopf A, Solomayer E, Fehm T, Müller V
BREAST CANCER RES TR. 2018;172(1):93-104.

Prevalence of circulating tumor cells in early breast cancer patients 2 and 5 years after adjuvant treatment
Bauer E, Schochter F, Widschwendter P, DeGregorio A, Andergassen U, Friedl T, Fasching P, Fehm T, Schneeweiss A, Beckmann M, Pantel K, Janni W, Rack B, Scholz C
BREAST CANCER RES TR. 2018;171(3):571-580.

Blockade of myeloid-derived suppressor cell expansion with all-trans retinoic acid increases the efficacy of anti-angiogenic therapy
Bauer R, Udonta F, Wroblewski M, Ben-Batalla I, Santos I, Taverna F, Kuhlencord M, Gensch V, Päsler S, Vinckier S, Brandner J, Pantel K, Bokemeyer C, Vogl T, Roth J, Carmeliet P, Loges S
CANCER RES. 2018;78(12):3220-3232.

Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib
Berger L, Janning M, Velthaus J, Ben-Batalla I, Schatz S, Falk M, Iglauer P, Simon R, Cao R, Forcato C, Manaresi N, Bramlett K, Buson G, Hanssen A, Tiemann M, Sauter G, Bokemeyer C, Riethdorf S, Reck M, Pantel K, Wikman H, Loges S
J THORAC ONCOL. 2018;13(12):e243-e246.

Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-Analysis: A Meta-analysis
Bidard F, Michiels S, Riethdorf S, Mueller V, Esserman L, Lucci A, Naume B, Horiguchi J, Gisbert-Criado R, Sleijfer S, Toi M, Garcia-Saenz J, Hartkopf A, Generali D, Rothé F, Smerage J, Muinelo-Romay L, Stebbing J, Viens P, Magbanua M, Hall C, Engebraaten O, Takata D, Vidal-Martínez J, Onstenk W, Fujisawa N, Diaz-Rubio E, Taran F, Cappelletti M, Ignatiadis M, Proudhon C, Wolf D, Bauldry J, Borgen E, Nagaoka R, Carañana V, Kraan J, Maestro M, Brucker S, Weber K, Reyal F, Amara D, Karhade M, Mathiesen R, Tokiniwa H, Llombart-Cussac A, Meddis A, Blanche P, d'Hollander K, Pantel K
JNCI-J NATL CANCER I. 2018;110(6):560-567.

Circulating free DNA integrity and concentration as independent prognostic markers in metastatic breast cancer
Cheng J, Holland-Letz T, Wallwiener M, Surowy H, Cuk K, Schott S, Trumpp A, Pantel K, Sohn C, Schneeweiss A, Burwinkel B
BREAST CANCER RES TR. 2018;169(1):69-82.

Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization
Chen S, El-Heliebi A, Schmid J, Kashofer K, Czyż Z, Polzer B, Pantel K, Kroneis T, Sedlmayr P
JOVE-J VIS EXP. 2018;(135):e56394.

miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes
Croset M, Pantano F, Kan C, Bonnelye E, Descotes F, Alix-Panabières C, Lecellier C, Bachelier R, Allioli N, Hong S, Bartkowiak K, Pantel K, Clézardin P
CANCER RES. 2018;78(18):5259-5273.

Improved risk stratification by circulating tumor cell counts in pancreatic cancer
Effenberger K, Schroeder C, Hanssen A, Wolter S, Eulenburg C, Tachezy M, Gebauer F, Izbicki J, Pantel K, Bockhorn M
CLIN CANCER RES. 2018;24(12):2844-2850.

In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges T, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P
CLIN CHEM. 2018;64(3):536-546.

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells
Follain G, Osmani N, Azevedo A, Allio G, Mercier L, Karreman M, Solecki G, Garcia Leòn M, Lefebvre O, Fekonja N, Hille C, Chabannes V, Dollé G, Metivet T, Hovsepian F, Prudhomme C, Pichot A, Paul N, Carapito R, Bahram S, Ruthensteiner B, Kemmling A, Siemonsen S, Schneider T, Fiehler J, Glatzel M, Winkler F, Schwab Y, Pantel K, Harlepp S, Goetz J
DEV CELL. 2018;45(1):33-52.e12.

Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases
Gerstenberger W, Wrage M, Kettunen E, Pantel K, Anttila S, Steurer S, Wikman H
ANAL CELL PATHOL. 2018;2018:8651790.

Metastasiertes kastrationsresistentes Prostatakarzinom: Neues zu Cabazitaxel unter Berücksichtigung der aktuellen Datenlage
Gschwend J, Albers P, Bögemann M, Goebell P, Heidenreich A, Klier J, König F, Machtens S, Pantel K, Thomas C
UROLOGE. 2018;57(1):34-39.

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen A, Riebensahm C, Mohme M, Joosse S, Velthaus J, Berger L, Bernreuther C, Glatzel M, Loges S, Lamszus K, Westphal M, Riethdorf S, Pantel K, Wikman H
CANCERS. 2018;10(12):E527.

Circulating tumour cells in prostate cancer
Hille C, Pantel K
NAT REV UROL. 2018;15(5):265-266.

Trastuzumab versus observation for HER2 non amplified early breast cancer with Circulating Tumor Cells (EORTC 90091-10093, BIG 1-12, Treat CTC): A randomized phase 2 trial
Ignatiadis M, Litière S, Rothe F, Riethdorf S, Proudhon C, Fehm T, Aalders K, Forstbauer H, Fasching P, Brain E, Vuylsteke P, Guardiola E, Lorenz R, Pantel K, Tryfonidis K, Janni W, Piccart M, Sotiriou C, Rack B, Pierga J
ANN ONCOL. 2018;29(8):1777-1783.

Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients
Joosse S, Souche F, Babayan A, Gasch C, Kerkhoven R, Ramos J, Fabre J, Riethdorf S, König A, Wikman H, Alix-Panabières C, Pantel K
CLIN CHEM. 2018;64(10):1505-1512.

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer
Lange T, Oh-Hohenhorst S, Joosse S, Pantel K, Hahn O, Gosau T, Dyshlovoy S, Wellbrock J, Feldhaus S, Maar H, Gehrcke R, Kluth M, Simon R, Schlomm T, Huland H, Schumacher U
SCI REP-UK. 2018;8:17535.

Intraoperative detection of circulating tumor cells in pulmonary venous blood during metastasectomy for colorectal lung metastases
Le U, Bronsert P, Picardo F, Riethdorf S, Haager B, Rylski B, Czerny M, Beyersdorf F, Wiesemann S, Pantel K, Passlick B, Kaifi J, Schmid S
SCI REP-UK. 2018;8(1):8751.

Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients
Markou A, Lazaridou M, Paraskevopoulos P, Chen S, Świerczewska M, Budna J, Kuske A, Gorges T, Joosse S, Kroneis T, Zabel M, Sedlmayr P, Alix-Panabières C, Pantel K, Lianidou E
CLIN CHEM. 2018;64(2):297-306.

Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients
Ni Q, Stevic I, Pan C, Müller V, Oliviera-Ferrer L, Pantel K, Schwarzenbach H
SCI REP-UK. 2018;8:12974.

Exosomal microRNAs as tumor markers in epithelial ovarian cancer
Pan C, Stevic I, Müller V, Ni Q, Ferrer L, Pantel K, Schwarzenbach H
MOL ONCOL. 2018;12(11):1935-1948.

Disseminated breast tumour cells: biological and clinical meaning: biological and clinical meaning
Pantel K, Hayes D
NAT REV CLIN ONCOL. 2018;15(3):129-131.

Profiling circulating tumour cells and other biomarkers of invasive cancers
Poudineh M, Sargent E, Pantel K, Kelley S
NAT BIOMED ENG. 2018;2(2):72-84.

Aktuelles zur Liquid Biopsy
Reimers N, Hille C, Pantel K
InFo Onkologie. 2018;21(Suppl. 1):24-29.

Clinical applications of the CellSearch platform in cancer patients
Riethdorf S, O'Flaherty L, Hille C, Pantel K
ADV DRUG DELIVER REV. 2018;125:102-121.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

Inverse Perfusion Requirements of Supra- and Infratentorial Brain Metastases Formation
Schneider T, Kemmling A, Schroeder J, Pantel K, Glatzel M, Schoen G, Mohme M, Fiehler J, Gellißen S
FRONT NEUROL. 2018;9:391.

Endocrine Treatment with 2 Years of Tamoxifen versus 2 Years of Exemestane in Postmenopausal Patients with High-Risk Early Breast Cancer and Persisting Circulating Tumor Cells - First Results of the SUCCESS C Endocrine Treatment Sub-Study
Schochter F, Rack B, Tzschaschel M, Polasik A, Andergassen U, Trapp E, Alunni-Fabbroni M, Schneeweiss A, Müller V, Pantel K, Gade J, Lorenz R, Rezai M, Tesch H, Soeling U, Fehm T, Mahner S, Schindlbeck C, Lichtenegger W, Beckmann M, Fasching P, Janni W, Friedl T
ONCOL RES TREAT. 2018;41(3):93-98.

Commentary on "Detection and oncological effect of circulating tumor cells in patients with variant urothelial carcinoma histology treated with radical cystectomy."
Soave A, Riethdorf S, Dahlem R, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
UROL ONCOL-SEMIN ORI. 2018;36(7):347-348.

Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes
Soler A, Cayrefourcq L, Mazard T, Babayan A, Lamy P, Assou S, Assenat E, Pantel K, Alix-Panabières C
SCI REP-UK. 2018;8(1):15931.

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial
Stevic I, Müller V, Weber K, Fasching P, Karn T, Marmé F, Schem C, Stickeler E, Denkert C, van Mackelenbergh M, Salat C, Schneeweiss A, Pantel K, Loibl S, Untch M, Schwarzenbach H
BMC MED. 2018;16(1):179.

Absence of HER2 Expression of Circulating Tumor Cells in Patients with Non-Metastatic Esophageal Cancer
Woestemeier A, Ghadban T, Riethdorf S, Harms-Effenberger K, Konczalla L, Uzunoglu F, Izbicki J, Pantel K, Bockhorn M, Reeh M
ANTICANCER RES. 2018;38(10):5665-5669.

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells
Wroblewski M, Scheller-Wendorff M, Udonta F, Bauer R, Schlichting J, Zhao L, Ben Batalla I, Gensch V, Päsler S, Wu L, Wanior M, Taipaleenmäki H, Bolamperti S, Najafova Z, Pantel K, Bokemeyer C, Qi J, Hesse E, Knapp S, Johnsen S, Loges S
HAEMATOLOGICA. 2018;103(6):939-948.

Epithelial-mesenchymal plasticity in circulating tumor cells
Alix-Panabières C, Mader S, Pantel K
J MOL MED. 2017;95(2):133-142.

Biological Labels: Here comes the spaser
Alix-Panabières C, Pantel K
NAT MATER. 2017;16(8):790-791.

Characterization of Single Circulating Tumor Cells
Alix-Panabières C, Pantel K
FEBS LETT. 2017;591(15):2241 - 2250.

Detection of Circulating Plasma Cells in Multiple Myeloma
Alix-Panabières C, Pantel K
CLIN CHEM. 2017;63(12):1797-1798.

Plasma microRNA signature is associated with risk stratification in prostate cancer patients
Al-Qatati A, Akrong C, Stevic I, Pantel K, Awe J, Saranchuk J, Drachenberg D, Mai S, Schwarzenbach H
INT J CANCER. 2017;141(6):1231-1239.

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan A, Alawi M, Gormley M, Müller V, Wikman H, McMullin R, Smirnov D, Li W, Geffken M, Pantel K, Joosse S
ONCOTARGET. 2017;8(34):56066-56080.

Clinical Relevance of Serum HER2 and Circulating Tumor Cell Detection in Metastatic Breast Cancer Patients
Banys-Paluchowski M, Witzel I, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Pantel K, Fehm T, Müller V
ANTICANCER RES. 2017;37(6):3117-3128.

Evaluation of serum epidermal growth factor receptor (EGFR) in correlation to circulating tumor cells in patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Pantel K, Fehm T, Müller V
SCI REP-UK. 2017;7(1):Art. 17307.

Liquid Biopsies, What We Do Not Know (Yet)
Bardelli A, Pantel K
CANCER CELL. 2017;31(2):172-179.

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia
Ben Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus J, Rankin S, Clark R, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf T, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason G, Holyoake T, Loges S
CLIN CANCER RES. 2017;23(9):2289-2300.

Catch and Release: rare cell analysis from a functionalised medical wire
Chen S, El-Heliebi A, Tauber G, Langsenlehner T, Pötscher M, Kashofer K, Czyż Z, Polzer B, Riethdorf S, Kuske A, Leitinger G, Pantel K, Kroneis T, Sedlmayr P
SCI REP-UK. 2017;7:43424.

Discordance in Human Epidermal Growth Factor Receptor 2 (HER2) Phenotype Between Primary Tumor and Circulating Tumor Cells in Women With HER2-Negative Metastatic Breast Cancer
de Gregorio A, Friedl T, Huober J, Scholz C, de Gregorio N, Rack B, Trapp E, Alunni-Fabbroni M, Riethdorf S, Muller V, Schneeweiss A, Pantel K, Meier-Stiegen F, Jaeger B, Hartkopf A, Taran F, Fasching P, Janni W, Fehm T
JCO PRECIS ONCOL. 2017;2017(1):1-12.

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee I, Chuang H, Grottke A, Werner S, Schulte A, Horn S, Lamszus K, Bartkowiak K, Witzel I, Westphal M, Matschke J, Glatzel M, Jücker M, Pukrop T, Pantel K, Wikman H
ONCOTARGET. 2017;8(4):6155-6168.

The HER2 phenotype of circulating tumor cells in HER2-positive early breast cancer: A translational research project of a prospective randomized phase III trial
Jaeger B, Neugebauer J, Andergassen U, Melcher C, Schochter F, Mouarrawy D, Ziemendorff G, Clemens M, V Abel E, Heinrich G, Schueller K, Schneeweiss A, Fasching P, Beckmann M, Scholz C, Friedl T, Friese K, Pantel K, Fehm T, Janni W, Rack B
PLOS ONE. 2017;12(6):e0173593.

PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells
Lehtinen L, Vainio P, Wikman H, Huhtala H, Mueller V, Kallioniemi A, Pantel K, Kronqvist P, Kallioniemi O, Carpèn O, Iljin K
J PATHOL CLIN RES. 2017;3(2):123-138.

Liquid Biopsy: Current Status and Future Perspectives
Mader S, Pantel K
ONCOL RES TREAT. 2017;40(7-8):404-408.

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme M, Riethdorf S, Dreimann M, Werner S, Maire C, Joosse S, Bludau F, Mueller V, Neves R, Stoecklein N, Lamszus K, Westphal M, Pantel K, Wikman H, Eicker S
SCI REP-UK. 2017;7(1):7196.

Circulating and disseminated tumour cells - mechanisms of immune surveillance and escape
Mohme M, Riethdorf S, Pantel K
NAT REV CLIN ONCOL. 2017;14(3):155-167.

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
O'Flaherty L, Wikman H, Pantel K
TRANSL LUNG CANCER R. 2017;6(4):431-443.

Liquid biopsy in 2016: Circulating tumour cells and cell-free DNA in gastrointestinal cancer
Pantel K, Alix-Panabières C
NAT REV GASTRO HEPAT. 2017;14(2):73-74.

Tumour microenvironment: informing on minimal residual disease in solid tumours
Pantel K, Alix-Panabières C
NAT REV CLIN ONCOL. 2017;14(6):325-326.

Cancer stem cells: The root of tumor recurrence and metastases
Peitzsch C, Tyutyunnykova A, Pantel K, Dubrovska A
SEMIN CANCER BIOL. 2017;44:10-24.

Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma
Reeh M, Ghadban T, Uzunoglu F, Nentwich M, Bockhorn M, Pantel K, Izbicki J, Vashist Y
BRIT J CANCER. 2017;117(5):612-618.

Prognostic impact of circulating tumor cells for breast cancer patients treated in the neoadjuvant "Geparquattro" trial
Riethdorf S, Müller V, Loibl S, Nekljudova V, Weber K, Huober J, Fehm T, Schrader I, Hilfrich J, Holms F, Tesch H, Schem C, von Minckwitz G, Untch M, Pantel K
CLIN CANCER RES. 2017;23(18):5384-5393.

Prevalence of Circulating Tumor Cells After Adjuvant Chemotherapy With or Without Anthracyclines in Patients With HER2-negative, Hormone Receptor-positive Early Breast Cancer
Schramm A, Schochter F, Friedl T, de Gregorio N, Andergassen U, Alunni-Fabbroni M, Trapp E, Jaeger B, Heinrich G, Camara O, Decker T, Ober A, Mahner S, Fehm T, Pantel K, Fasching P, Schneeweiss A, Janni W, Rack B
CLIN BREAST CANCER. 2017;17(4):279-285.

Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study
Soave A, Chun F, Hillebrand T, Rink M, Weisbach L, Steinbach B, Fisch M, Pantel K, Schwarzenbach H
ONCOTARGET. 2017;8(34):56398-56407.

Detection and oncological effect of circulating tumour cells in patients with variant urothelial carcinoma histology treated with radical cystectomy
Soave A, Riethdorf S, Dahlem R, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
BJU INT. 2017;119(6):854-861.

A nonrandomized, prospective, clinical study on the impact of circulating tumor cells on outcomes of urothelial carcinoma of the bladder patients treated with radical cystectomy with or without adjuvant chemotherapy
Soave A, Riethdorf S, Dahlem R, von Amsberg G, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
INT J CANCER. 2017;140(2):381-389.

Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection
von Felden J, Schulze K, Krech T, Ewald F, Nashan B, Pantel K, Lohse A, Riethdorf S, Wege H
ONCOTARGET. 2017;8(52):89978-89987.

Tracing the Seeds in the Soil
Werner S, Pantel K
CLIN CHEM. 2017;63(11):1764-1765.

Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells
Werner S, Stenzl A, Pantel K, Todenhöfer T
ADV EXP MED BIOL. 2017;994:205-228.

Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer
Wikman H, Pantel K
CLIN CHEM. 2017;63(8):1318-1320.

Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B
Wroblewski M, Bauer R, Cubas Córdova M, Udonta F, Ben-Batalla I, Legler K, Hauser C, Egberts J, Janning M, Velthaus J, Schulze C, Pantel K, Bokemeyer C, Loges S
NAT COMMUN. 2017;8(1):269.

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy
Zheng H, Bae Y, Kasimir-Bauer S, Tang R, Chen J, Ren G, Yuan M, Esposito M, Li W, Wei Y, Shen M, Zhang L, Tupitsyn N, Pantel K, King C, Sun J, Moriguchi J, Jun H, Coxon A, Lee B, Kang Y
CANCER CELL. 2017;32(6):731-747.e6.

Comparison of the HER2, estrogen and progesterone receptor expression profile of primary tumor, metastases and circulating tumor cells in metastatic breast cancer patients
Aktas B, Kasimir-Bauer S, Müller V, Janni W, Fehm T, Wallwiener D, Pantel K, Tewes M
BMC CANCER. 2016;16:522.

Functional studies on circulating and disseminated tumor cells in carcinoma patients
Alix-Panabières C, Bartkowiak K, Pantel K
MOL ONCOL. 2016;10(3):443-9.

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy
Alix-Panabières C, Pantel K
CANCER DISCOV. 2016;6(5):479-91.

Cancer: A shocking protein complex
Bartkowiak K, Pantel K
NATURE. 2016;538(7625):322-323.

Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll N, Efstathiou A, Gotzhein F, Wikman H, Mueller V, Kang Y, Pantel K
CLIN CHEM. 2016;62(2):378-386.

Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer
Deutsch T, Riethdorf S, Nees J, Hartkopf A, Schönfisch B, Domschke C, Sprick M, Schütz F, Brucker S, Stefanovic S, Sohn C, Pantel K, Trumpp A, Schneeweiss A, Wallwiener M
BREAST CANCER RES TR. 2016;160(2):277-290.

Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer
Gasch C, Oldopp T, Mauermann O, Gorges T, Andreas A, Coith C, Müller V, Fehm T, Janni W, Pantel K, Riethdorf S
MOL ONCOL. 2016;10(8):1330-43.

Diverse prognostic value of the GTn promoter polymorphism in squamous cell and adeno carcinoma of the esophageus
Ghadban T, Miro J, Trump F, Tsui T, Uzunoglu F, Reeh M, Gebauer F, Bachmann K, Wellner U, Kalinin V, Pantel K, Izbicki J, Vashist Y
CLIN GENET. 2016;90(4):343-50.

Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells
Gorges T, Kuske A, Röck K, Mauermann O, Müller V, Peine S, Verpoort K, Novosadova V, Kubista M, Riethdorf S, Pantel K
CLIN CHEM. 2016;62(11):1504-1515.

Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells
Gorges T, Penkalla N, Schalk T, Joosse S, Riethdorf S, Tucholski J, Lucke K, Wikman H, Jackson S, Brychter N, von Ahsen O, Schumann C, Krahn T, Pantel K
CLIN CANCER RES. 2016;22(9):2197-206.

Heterogeneous PSMA expression on circulating tumor cells - a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer
Gorges T, Riethdorf S, von Ahsen O, Nastały P, Röck K, Boede M, Peine S, Kuske A, Schmid E, Kneip C, König F, Rudolph M, Pantel K
ONCOTARGET. 2016;7(23):34930-41.

Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest®
Gorges T, Stein A, Quidde J, Hauch S, Röck K, Riethdorf S, Joosse S, Pantel K
PLOS ONE. 2016;11(5):e0155126.

Perspectives on sipuleucel-T: Its role in the prostate cancer treatment paradigm
Gulley J, Mulders P, Albers P, Banchereau J, Bolla M, Pantel K, Powles T
ONCOIMMUNOLOGY. 2016;5(4):e1107698.

Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen A, Wagner J, Gorges T, Tänzer A, Uzunoglu F, Driemel C, Stoecklein N, Knoefel W, Angenendt S, Hauch S, Atanackovic D, Loges S, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2016;6:28010.

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia G, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves R, Stoecklein N, Wikman H, Riethdorf S, Pantel K, Gorges T
INT J CANCER. 2016;138(12):2894-904.

Liquid biopsy-based clinical research in early breast cancer: The EORTC 90091-10093 Treat CTC trial
Ignatiadis M, Rack B, Rothé F, Riethdorf S, Decraene C, Bonnefoi H, Dittrich C, Messina C, Beauvois M, Trapp E, Goulioti T, Tryfonidis K, Pantel K, Repollet M, Janni W, Piccart M, Sotiriou C, Litiere S, Pierga J
EUR J CANCER. 2016;63:97-104.

Pooled Analysis of the Prognostic Relevance of Circulating Tumor Cells in Primary Breast Cancer
Janni W, Rack B, Terstappen L, Pierga J, Taran F, Fehm T, Hall C, de Groot M, Bidard F, Friedl T, Fasching P, Brucker S, Pantel K, Lucci A
CLIN CANCER RES. 2016;22(10):2583-93.

Genetic traits for hematogeneous tumor cell dissemination in cancer patients
Joosse S, Pantel K
CANCER METAST REV. 2016;35(1):41-8.

Detection of circulating tumor cells using manually performed immunocytochemistry (MICC) does not correlate with outcome in patients with early breast cancer - Results of the German SUCCESS-A- trial
Jueckstock J, Rack B, Friedl T, Scholz C, Steidl J, Trapp E, Tesch H, Forstbauer H, Lorenz R, Rezai M, Häberle L, Alunni-Fabbroni M, Schneeweiss A, Beckmann M, Lichtenegger W, Fasching P, Pantel K, Janni W
BMC CANCER. 2016;16:401.

Improved detection of circulating tumor cells in non-metastatic high-risk prostate cancer patients
Kuske A, Gorges T, Tennstedt P, Tiebel A, Pompe R, Preißer F, Prues S, Mazel M, Markou A, Lianidou E, Peine S, Alix-Panabières C, Riethdorf S, Beyer B, Schlomm T, Pantel K
SCI REP-UK. 2016;6:39736.

Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction?
Leung F, Kulasingam V, Diamandis E, Hoon D, Kinzler K, Pantel K, Alix-Panabières C
CLIN CHEM. 2016;62(8):1054-60.

Circulating miRNAs with prognostic value in metastatic breast cancer and for early detection of metastasis
Madhavan D, Peng C, Wallwiener M, Zucknick M, Nees J, Schott S, Rudolph A, Riethdorf S, Trumpp A, Pantel K, Sohn C, Chang-Claude J, Schneeweiss A, Burwinkel B
CARCINOGENESIS. 2016;37(5):461 - 470.

Circulating Cell-Free miR-373, miR-200a, miR-200b and miR-200c in Patients with Epithelial Ovarian Cancer
Meng X, Müller V, Milde-Langosch K, Trillsch F, Pantel K, Schwarzenbach H
ADV EXP MED BIOL. 2016;924:3-8.

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer
Meng X, Müller V, Milde-Langosch K, Trillsch F, Pantel K, Schwarzenbach H
ONCOTARGET. 2016;7(13):16923-35.

Limited prognostic value of preoperative circulating tumor cells for early biochemical recurrence in patients with localized prostate cancer
Meyer C, Pantel K, Tennstedt P, Stroelin P, Schlomm T, Heinzer H, Riethdorf S, Steuber T
UROL ONCOL-SEMIN ORI. 2016;34(5):235.e11-6.

Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection
Pantel K
PLOS MED. 2016;13(12):e1002205.

TP53 mutations on circulating cell-free DNA
Pantel K
EBIOMEDICINE. 2016;10:15-6.

Functional Studies on Viable Circulating Tumor Cells
Pantel K, Alix-Panabières C
CLIN CHEM. 2016;62(2):328-34.

Liquid biopsy: Potential and challenges
Pantel K, Alix-Panabières C
MOL ONCOL. 2016;10(3):371-3.

The biology of circulating tumor cells
Pantel K, Speicher M
ONCOGENE. 2016;35(10):1216-24.

Plasma S100P level as a novel prognostic marker of metastatic breast cancer
Peng C, Chen H, Wallwiener M, Modugno C, Cuk K, Madhavan D, Trumpp A, Heil J, Marmé F, Nees J, Riethdorf S, Schott S, Sohn C, Pantel K, Schneeweiss A, Yang R, Burwinkel B
BREAST CANCER RES TR. 2016;157(2):329-38.

Plasma Hyaluronic Acid level as a Prognostic and Monitoring Marker of Metastatic Breast Cancer
Peng C, Wallwiener M, Rudolph A, Ćuk K, Eilber U, Celik M, Modugno C, Trumpp A, Heil J, Marmé F, Madhavan D, Nees J, Riethdorf S, Schott S, Sohn C, Pantel K, Schneeweiss A, Chang-Claude J, Yang R, Burwinkel B
INT J CANCER. 2016;138(10):2499-509.

Liquid biopsies for surveillance and monitoring treatment response of bladder cancer
Riethdorf S, Pantel K
J TRANSL MED. 2016;4(19):379.

Chronic UVB-irradiation actuates perpetuated dermal matrix remodeling in female mice: Protective role of estrogen
Röck K, Joosse S, Müller J, Heinisch N, Fuchs N, Meusch M, Zipper P, Reifenberger J, Pantel K, Fischer J
SCI REP-UK. 2016;6:30482.

Potential of circulating tumor cells as blood-based biomarkers in cancer liquid biopsy
Schlange T, Pantel K
PHARMACOGENOMICS. 2016;17(3):183-6.

Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program
Schramm A, Friedl T, Schochter F, Scholz C, de Gregorio N, Huober J, Rack B, Trapp E, Alunni-Fabbroni M, Müller V, Schneeweiss A, Pantel K, Meier-Stiegen F, Hartkopf A, Taran F, Wallwiener D, Janni W, Fehm T
ARCH GYNECOL OBSTET. 2016;293(2):271-81.

RHAMM splice variants confer radiosensitivity in human breast cancer cell lines
Schütze A, Vogeley C, Gorges T, Twarock S, Butschan J, Babayan A, Klein D, Knauer S, Metzen E, Müller V, Jendrossek V, Pantel K, Milde-Langosch K, Fischer J, Röck K
ONCOTARGET. 2016;7(16):21428-40.

Breast cancer brain metastases:biology and new clinical perspectives
Witzel I, Oliveira-Ferrer L, Pantel K, Müller V, Wikman H
BREAST CANCER RES. 2016;18(1):8.

Liquid biopsy in cancer patients: advances in capturing viable CTCs for functional studies using the EPISPOT assay
Alix-Panabières C, Pantel K
EXPERT REV MOL DIAGN. 2015;15(11):1411-7.

Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak K, Kwiatkowski M, Buck F, Gorges T, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K
CANCER RES. 2015;75(24):5367-77.

Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Bednarz-Knoll N, Nastały P, Żaczek A, Stoupiec M, Riethdorf S, Wikman-Kocher H, Müller V, Skokowski J, Szade J, Sejda A, Wełnicka-Jaśkiewicz M, Pantel K
ONCOTARGET. 2015;6(29):26789-803.

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs
Ben-Batalla I, Cubas-Cordova M, Udonta F, Wroblewski M, Waizenegger J, Janning M, Sawall S, Gensch V, Zhao L, Martinez-Zubiaurre I, Riecken K, Fehse B, Pantel K, Bokemeyer C, Loges S
ONCOTARGET. 2015;6(8):6341-58.

A Versatile Microarray Platform for Capturing Rare Cells
Brinkmann F, Hirtz M, Haller A, Gorges T, Vellekoop M, Riethdorf S, Müller V, Pantel K, Fuchs H
SCI REP-UK. 2015;5:Art. 15342.

Establishment and characterization of a cell line from human circulating colon cancer cells
Cayrefourcq L, Mazard T, Joosse S, Solassol J, Ramos J, Assenat E, Schumacher U, Costes V, Maudelonde T, Pantel K, Alix-Panabières C
CANCER RES. 2015;75(5):892-901.

Whole Genome Amplification in Genomic Analysis of Single Circulating Tumor Cells
Gasch C, Pantel K, Riethdorf S
Methods Mol Biol. 2015;1347:221-32.

Heterogeneity of miR-10b expression in circulating tumor cells
Gasch C, Plummer P, Jovanovic L, McInnes L, Wescott D, Saunders C, Schneeweiss A, Wallwiener M, Nelson C, Spring K, Riethdorf S, Thompson E, Pantel K, Mellick A
SCI REP-UK. 2015;5:Art. 15980.

Evaluation of the germline single nucleotide polymorphism rs583522 in the TNFAIP3 gene as a prognostic marker in esophageal cancer
Ghadban T, Schmidt-Yang M, Uzunoglu F, Perez D, El Gammal A, Miro J, Wellner U, Pantel K, Izbicki J, Vashist Y
CANCER GENET-NY. 2015;208(12):595–601.

Correction to: An A/C germline single-nucleotide polymorphism in the TNFAIP3 gene is associated with advanced disease stage and survival in only surgically treated esophageal cancer
Ghadban T, Schmidt-Yang M, Uzunoglu F, Perez D, Tsui T, El Gammal A, Erbes P, Zilbermints V, Wellner U, Pantel K, Izbicki J, Vashist Y
J HUM GENET. 2015;60(2):107.

„Liquid Biopsy“ – Nachweis und Charakterisierung von zirkulierenden Tumorzellen
Gorges T, Riethdorf S, Pantel K
2015;Spitzenforschung in der Onkologie:.

Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
Hanssen A, Loges S, Pantel K, Wikman-Kocher H
FRONT ONCOL. 2015;5:Art. 207.

Tumour exosome integrins determine organotropic metastasis
Hoshino A, Costa-Silva B, Shen T, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies A, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss J, Dumont-Cole V, Kramer K, Wexler L, Narendran A, Schwartz G, Healey J, Sandstrom P, Jørgen Labori K, Kure E, Grandgenett P, Hollingsworth M, de Sousa M, Kaur S, Jain M, Mallya K, Batra S, Jarnagin W, Brady M, Fodstad O, Muller V, Pantel K, Minn A, Bissell M, Garcia B, Kang Y, Rajasekhar V, Ghajar C, Matei I, Peinado H, Bromberg J, Lyden D
NATURE. 2015;527(7578):329-35.

Biology, detection, and clinical implications of circulating tumor cells
Joosse S, Gorges T, Pantel K
EMBO MOL MED. 2015;7(1):1-11.

Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients
Joosse S, Pantel K
CANCER CELL. 2015;28(5):552-4.

Mutant p53 promotes epithelial-mesenchymal plasticity and enhances metastasis in mammary carcinomas of WAP-T mice
Lenfert E, Mänz C, Heinlein C, Jannasch K, Schumacher U, Pantel K, Tolstonog G, Deppert W, Wegwitz F
INT J CANCER. 2015;136(6):E521-E533.

Epithelial-mesenchymal plasticity is a decisive feature for the metastatic outgrowth of disseminated WAP-T mouse mammary carcinoma cells
Maenz C, Lenfert E, Pantel K, Schumacher U, Deppert W, Wegwitz F
BMC CANCER. 2015;15:178.

Frequent expression of PD-L1 on circulating breast cancer cells
Mazel M, Jacot W, Pantel K, Bartkowiak K, Topart D, Cayrefourcq L, Rossille D, Maudelonde T, Fest T, Alix-Panabières C
MOL ONCOL. 2015;9(9):1773-82.

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
Meng X, Joosse S, Müller V, Trillsch F, Milde-Langosch K, Mahner S, Geffken M, Pantel K, Schwarzenbach H
BRIT J CANCER. 2015;113(9):1358-1366.

Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients
Milde-Langosch K, Schütze D, Oliveira-Ferrer L, Wikman-Kocher H, Müller V, Lebok P, Pantel K, Schröder C, Witzel I, Schumacher U
BREAST CANCER RES TR. 2015;151(3):515-28.

Disseminierte und zirkulierende Tumorzellen, zirkulierende DNA und RNA im Blut - Biomarker beim Mammakarzinom?
Muller V, Riethdorf S, Pantel K
2015. Tumorbiologie und Diagnostik des primären Mammakarzinoms. Vetter M, Kantelhardt E (Hrsg.). 1. Aufl. Bremen: Uni-Med, 84-91.

Cell lines from circulating tumor cells: Comment on: Establishment and Characterization of a Cell Line from Human Circulating Colon Cancer Cells. Cancer Res. 2015 Mar 1; 75(5): 892-901
Pantel K, Alix-Panabières C
Oncoscience. 2015;2(10):815-6.

Circulating Tumor Cells as a Biomarker for Preoperative Prognostic Staging in Patients With Esophageal Cancer
Reeh M, Harms-Effenberger K, Koenig A, Riethdorf S, Eichstädt D, Vettorazzi E, Uzunoglu F, Vashist Y, Izbicki J, Pantel K, Bockhorn M
ANN SURG. 2015;261(6):1124-30.

Diverse expression patterns of the EMT suppressor grainyhead-like 2 (GRHL2) in normal and tumour tissues
Riethdorf S, Frey S, Santjer S, Stoupiec M, Otto B, Riethdorf L, Koop C, Wilczak W, Simon R, Sauter G, Pantel K, Assmann V
INT J CANCER. 2015;138:949-963.

Data Normalization Strategies for MicroRNA Quantification
Schwarzenbach H, Machado da Silva A, Calin G, Pantel K
CLIN CHEM. 2015;61(11):1333-42.

Circulating DNA as biomarker in breast cancer
Schwarzenbach H, Pantel K
BREAST CANCER RES. 2015;17:Art. 136.

Do circulating tumor cells have a role in deciding on adjuvant chemotherapy after radical cystectomy?
Soave A, Riethdorf S, Pantel K, Fisch M, Rink M
CURR UROL REP. 2015;16(7):Art. 46.

Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients
Stückrath I, Rack B, Janni W, Jäger B, Pantel K, Schwarzenbach H
ONCOTARGET. 2015;6(15):13387-401.

Circulating tumour cell-derived plastin3 is a novel marker for predicting long-term prognosis in patients with breast cancer
Ueo H, Sugimachi K, Gorges T, Bartkowiak K, Yokobori T, Müller V, Shinden Y, Ueda M, Ueo H, Mori M, Kuwano H, Maehara Y, Ohno S, Pantel K, Mimori K
BRIT J CANCER. 2015;112(9):1519-26.

Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma
Waizenegger J, Ben-Batalla I, Weinhold N, Meissner T, Wroblewski M, Janning M, Riecken K, Binder M, Atanackovic D, Taipaleenmaeki H, Schewe D, Sawall S, Gensch V, Cubas-Cordova M, Seckinger A, Fiedler W, Hesse E, Kröger N, Fehse B, Hose D, Klein B, Raab M, Pantel K, Bokemeyer C, Loges S
LEUKEMIA. 2015;29(3):696-704.

The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients
Wallwiener M, Hartkopf A, Riethdorf S, Nees J, Sprick M, Schönfisch B, Taran F, Heil J, Sohn C, Pantel K, Trumpp A, Schneeweiss A
BMC CANCER. 2015;15:Art. 403.

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret A, Kemming D, Wood A, Edgren H, Neubauer H, Streichert T, Riethdorf S, Bedi U, Baccelli I, Jücker M, Eils R, Fehm T, Trumpp A, Johnsen S, Klefstrom J, Wilmanns M, Müller V, Pantel K, Wikman-Kocher H
CANCER DISCOV. 2015;5(5):506-19.

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells
Werner S, Stamm H, Pandjaitan M, Kemming D, Brors B, Pantel K, Wikman H
BMC CANCER. 2015;15(1):896.

Identification of HERC5 and its potential role in NSCLC progression
Wrage M, Hagmann W, Kemming D, Uzunoglu F, Riethdorf S, Harms-Effenberger K, Westphal M, Lamszus K, Kim S, Becker N, Izbicki J, Sandoval J, Esteller M, Pantel K, Risch A, Wikman-Kocher H
INT J CANCER. 2015;136(10):2264-72.

[The Circulating Tumor Cells: Liquid Biopsy of Cancer]
Alix-Panabieres C, Pantel K
Klinicheskaia laboratornaia diagnostika. 2014;(4):60-4.

Opinion: Challenges in circulating tumour cell research
Alix-Panabières C, Pantel K
NAT REV CANCER. 2014;14(9):623-631.

Technologies for detection of circulating tumor cells: facts and vision
Alix-Panabières C, Pantel K
LAB CHIP. 2014;14(1):57-62.

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data: a pooled analysis of individual patient data
Bidard F, Peeters D, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Generali D, Garcia-Saenz J, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, de Lascoiti A, De Mattos-Arruda L, Ignatiadis M, Lebofsky R, van Laere S, Meier-Stiegen F, Sandri M, Vidal-Martinez J, Politaki E, Consoli F, Bottini A, Diaz-Rubio E, Krell J, Dawson S, Raimondi C, Rutten A, Janni W, Munzone E, Carañana V, Agelaki S, Almici C, Dirix L, Solomayer E, Zorzino L, Johannes H, Reis-Filho J, Pantel K, Pierga J, Michiels S
LANCET ONCOL. 2014;15(4):406-414.

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
Eichelser C, Stückrath I, Müller V, Milde-Langosch K, Wikman-Kocher H, Pantel K, Schwarzenbach H
ONCOTARGET. 2014;5(20):9650-63.

Circulating tumor cells detection has independent prognostic impact in high-risk non-muscle invasive bladder cancer
Gazzaniga P, de Berardinis E, Raimondi C, Gradilone A, Busetto G, De Falco E, Nicolazzo C, Giovannone R, Gentile V, Cortesi E, Pantel K
INT J CANCER. 2014;135(8):1978-1982.

An A/C germline single-nucleotide polymorphism in the TNFAIP3 gene is associated with advanced disease stage and survival in only surgically treated esophageal cancer
Ghadban T, Schmidt-Yang M, Uzunoglu F, Perez D, Tsui T, El Gammal A, Erbes P, Zilbermints V, Wellner U, Pantel K, Izbicki J, Vashist Y
J HUM GENET. 2014;59(12):661-666.

Pathogenesis of Minimal Residual Disease: CTCs as Novel Biomarkers in Cancer Disease
Gorges T, Pantel K
2014;Part 1:.

AKT3 regulates ErbB2, ErbB3 and estrogen receptor α expression and contributes to endocrine therapy resistance of ErbB2(+) breast tumor cells from Balb-neuT mice
Grabinski N, Möllmann K, Milde-Langosch K, Müller V, Schumacher U, Brandt B, Pantel K, Jücker M
CELL SIGNAL. 2014;26(5):1021-9.

Prognostic relevance of circulating tumor cells in blood and disseminated tumor cells in bone marrow of patients with squamous cell carcinoma of the oral cavity
Gröbe A, Blessmann M, Hanken H, Friedrich R, Schön G, Wikner J, Harms-Effenberger K, Kluwe L, Heiland M, Pantel K, Riethdorf S
CLIN CANCER RES. 2014;20(2):425-33.

The dynamic range of circulating tumor DNA in metastatic breast cancer
Heidary M, Auer M, Ulz P, Heitzer E, Petru E, Gasch C, Riethdorf S, Mauermann O, Lafer I, Pristauz G, Lax S, Pantel K, Geigl J, Speicher M
BREAST CANCER RES. 2014;16(4):421.

International study on inter-reader variability for circulating tumor cells in breast cancer
Ignatiadis M, Riethdorf S, Bidard F, Vaucher I, Khazour M, Rothé F, Metallo J, Rouas G, Payne R, Coombes R, Teufel I, Andergassen U, Apostolaki S, Politaki E, Mavroudis D, Bessi S, Pestrin M, Di Leo A, Campion M, Reinholz M, Perez E, Piccart M, Borgen E, Naume B, Jimenez J, Aura C, Zorzino L, Cassatella M, Sandri M, Mostert B, Sleijfer S, Kraan J, Janni W, Fehm T, Rack B, Terstappen L, Repollet M, Pierga J, Miller C, Sotiriou C, Michiels S, Pantel K
BREAST CANCER RES. 2014;16(2):R43.

Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases
Joosse S, Müller V, Steinbach B, Pantel K, Schwarzenbach H
BRIT J CANCER. 2014;111(5):909-17.

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
LeBleu V, O'Connell J, Gonzalez Herrera K, Wikman-Kocher H, Pantel K, Haigis M, de Carvalho F, Damascena A, Domingos Chinen L, Rocha R, Asara J, Kalluri R
NAT CELL BIOL. 2014;16(10):992-1003.

Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis
Madhavan D, Wallwiener M, Bents K, Zucknick M, Nees J, Schott S, Cuk K, Riethdorf S, Trumpp A, Pantel K, Sohn C, Schneeweiss A, Surowy H, Burwinkel B
BREAST CANCER RES TR. 2014;146(1):163-174.

Circulating tumor cells in head and neck cancer: clinical impact in diagnosis and follow-up
Möckelmann N, Laban S, Pantel K, Knecht R
EUR ARCH OTO-RHINO-L. 2014;271(1):15-21.

Hematogenous dissemination of glioblastoma multiforme
Müller C, Holtschmidt J, Auer M, Heitzer E, Lamszus K, Schulte A, Matschke J, Langer-Freitag S, Gasch C, Stoupiec M, Mauermann O, Peine S, Glatzel M, Speicher M, Geigl J, Westphal M, Pantel K, Riethdorf S
SCI TRANSL MED. 2014;6(247):247ra101.

Changes in serum levels of miR-21, miR-210, and miR-373 in HER2-positive breast cancer patients undergoing neoadjuvant therapy: a translational research project within the Geparquinto trial
Müller V, Gade S, Steinbach B, Loibl S, von Minckwitz G, Untch M, Schwedler K, Lübbe K, Schem C, Fasching P, Mau C, Pantel K, Schwarzenbach H
BREAST CANCER RES TR. 2014;147(1):61-8.

Circulating tumor cells in patients with testicular germ cell tumors
Nastały P, Ruf C, Becker P, Bednarz-Knoll N, Stoupiec M, Kavsur R, Isbarn H, Matthies C, Wagner W, Höppner D, Fisch M, Bokemeyer C, Ahyai S, Honecker F, Riethdorf S, Pantel K
CLIN CANCER RES. 2014;20(14):3830-41.

Bone marrow as a reservoir for disseminated tumor cells: a special source for liquid biopsy in cancer patients: a special source for liquid biopsy in cancer patients
Pantel K, Alix-Panabières C
Bonekey Rep. 2014;3:584.

Circulating tumor cells predict survival in early average-to-high risk breast cancer patients
Rack B, Schindlbeck C, Jückstock J, Andergassen U, Hepp P, Zwingers T, Friedl T, Lorenz R, Tesch H, Fasching P, Fehm T, Schneeweiss A, Lichtenegger W, Beckmann M, Friese K, Pantel K, Janni W
JNCI-J NATL CANCER I. 2014;106(5):.

Prognostic relevance of viable circulating tumor cells detected by EPISPOT in metastatic breast cancer patients
Ramirez J, Fehm T, Orsini M, Cayrefourcq L, Maudelonde T, Pantel K, Alix-Panabières C
CLIN CHEM. 2014;60(1):214-221.

Erratum zu: Detektion und Stellenwert von zirkulierenden Tumorzellen im peripheren Blut beim Urothelkarzinom der Harnblase
Rink M, Soave A, Engel O, Fisch M, Riethdorf S, Pantel K
UROLOGE. 2014;53(5):740.

Zirkulierende Tumorzellen im peripheren Blut beim Urothelkarzinom der Harnblase: Detektion und Stellenwert
Rink M, Soave A, Engel O, Fisch M, Riethdorf S, Pantel K
UROLOGE. 2014;53(4):501-508.

Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein
Schwarzenbach H, Eichelser C, Steinbach B, Tadewaldt J, Pantel K, Lobanenkov V, Loukinov D
BMC CANCER. 2014;14:796.

Clinical relevance of circulating cell-free microRNAs in cancer
Schwarzenbach H, Nishida N, Calin G, Pantel K
NAT REV CLIN ONCOL. 2014;11(3):145-156.

Circulating MicroRNAs as Non-Invasive Biomarkers
Schwarzenbach H, Pantel K
2014. MicroRNAs in Medicine. Lawrie C (Hrsg.). 1. Aufl. Wiley-Blackwell, 567-588.

Tumor signatures in the blood
Speicher M, Pantel K
NAT BIOTECHNOL. 2014;32(5):441-3.

Prognostic impact of perineural, blood and lymph vessel invasion for esophageal cancer
Tachezy M, Tiebel A, Gebauer F, Kutup A, Tharun L, Pantel K, Izbicki J, Vashist Y
HISTOPATHOLOGY. 2014;29(11):1467-1475.

Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer
Uzunoglu F, Dethlefsen E, Hanssen A, Wrage M, Deutsch L, Harms-Effenberger K, Vashist Y, Reeh M, Sauter G, Simon R, Bockhorn M, Pantel K, Izbicki J, Wikman-Kocher H
PLOS ONE. 2014;9(12):e113315.

EGFR intron-1 CA repeat polymorphism is a predictor of relapse and survival in complete resected only surgically treated esophageal cancer
Vashist Y, Trump F, Gebauer F, Kutup A, Güngör C, Kalinin V, Muddasar R, Vettorazzi E, Yekebas E, Brandt B, Pantel K, Izbicki J
TARGET ONCOL. 2014;9(1):43-52.

Serial enumeration of circulating tumor cells predicts treatment response andprognosis in metastatic breast cancer: a prospective study in 393 patients
Wallwiener M, Riethdorf S, Hartkopf A, Modugno C, Nees J, Madhavan D, Sprick M, Schott S, Domschke C, Baccelli I, Schönfisch B, Burwinkel B, Marmé F, Heil J, Sohn C, Pantel K, Trumpp A, Schneeweiss A
BMC CANCER. 2014;14:512.

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher H, Westphal L, Schmid F, Pollari S, Kropidlowski J, Sielaff-Frimpong B, Glatzel M, Matschke J, Westphal M, Iljin K, Huhtala H, Terracciano L, Kallioniemi A, Sauter G, Müller V, Witzel I, Lamszus K, Kemming D, Pantel K
ONCOTARGET. 2014;5(10):3076-3087.

Squamous cell carcinoma of the oral cavity and circulating tumour cells
Wikner J, Gröbe A, Pantel K, Riethdorf S
WORLD J CLIN ONCOL. 2014;5(2):114-124.

Circulating tumor cells: liquid biopsy of cancer.
Alix-Panabières C, Pantel K
CLIN CHEM. 2013;59(1):110-118.

Real-time liquid biopsy: circulating tumor cells versus circulating tumor DNA
Alix-Panabières C, Pantel K
J TRANSL MED. 2013;1(2):18.

Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients
Babayan A, Hannemann J, Spötter J, Müller V, Pantel K, Joosse S
PLOS ONE. 2013;8(9):e75038.

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, Bäuerle T, Wallwiener M, Holland-Letz T, Höfner T, Sprick M, Scharpff M, Marmé F, Sinn H, Pantel K, Weichert W, Trumpp A
NAT BIOTECHNOL. 2013;31(6):539-44.

Definition of molecular determinants of prostate cancer cell bone extravasation.
Barthel S, Hays D, Yazawa E, Opperman M, Walley K, Nimrichter L, Burdick M, Gillard B, Moser M, Pantel K, Foster B, Pienta K, Dimitroff C
CANCER RES. 2013;73(2):942-952.

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma
Ben Batalla I, Schultze A, Wroblewski M, Erdmann R, Heuser M, Waizenegger J, Riecken K, Binder M, Schewe D, Sawall S, Witzke V, Cubas Cordova M, Janning M, Wellbrock J, Fehse B, Hagel C, Krauter J, Ganser A, Lorens J, Fiedler W, Carmeliet P, Pantel K, Bokemeyer C, Loges S
BLOOD. 2013;122(14):2443-52.

Capture of viable circulating tumor cells in the liver of colorectal cancer patients
Denève E, Riethdorf S, Ramos J, Nocca D, Coffy A, Daurès J, Maudelonde T, Fabre J, Pantel K, Alix-Panabières C
CLIN CHEM. 2013;59(9):1384-92.

Deregulated serum concentrations of circulating cell-free microRNAs miR-17, miR-34a, miR-155, and miR-373 in human breast cancer development and progression
Eichelser C, Flesch-Janys D, Chang-Claude J, Pantel K, Schwarzenbach H
CLIN CHEM. 2013;59(10):1489-96.

Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis
Ell B, Mercatali L, Ibrahim T, Campbell N, Schwarzenbach H, Pantel K, Amadori D, Kang Y
CANCER CELL. 2013;24(4):542-56.

Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.
Gasch C, Bauernhofer T, Pichler M, Langer-Freitag S, Reeh M, Seifert A, Mauermann O, Izbicki J, Pantel K, Riethdorf S
CLIN CHEM. 2013;59(1):252-260.

Circulating tumor cells as therapy-related biomarkers in cancer patients.
Gorges T, Pantel K
CANCER IMMUNOL IMMUN. 2013;62(5):931-939.

Frequent intratumoral heterogeneity of EGFR gene copy gain in non-small cell lung cancer
Grob T, Hoenig T, Clauditz T, Atanackovic D, Koenig A, Vashist Y, Klose H, Simon R, Pantel K, Izbicki J, Bokemeyer C, Sauter G, Wilczak W
LUNG CANCER. 2013;79(3):221-7.

Correction: Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer
Gros S, Kurschat N, Drenckhan A, Dohrmann T, Forberich E, Harms-Effenberger K, Reichelt U, Hoffmann R, Pantel K, Kaifi J, Izbicki J
PLOS ONE. 2013;8(5):.

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing
Heitzer E, Auer M, Gasch C, Pichler M, Ulz P, Hoffmann E, Lax S, Waldispuehl-Geigl J, Mauermann O, Lackner C, Höfler G, Eisner F, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl J, Speicher M
CANCER RES. 2013;73(10):2965-75.

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer
Heitzer E, Auer M, Hoffmann E, Pichler M, Gasch C, Ulz P, Lax S, Waldispuehl-Geigl J, Mauermann O, Mohan S, Pristauz G, Lackner C, Höfler G, Eisner F, Petru E, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl J, Speicher M
INT J CANCER. 2013;133(2):346-56.

Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
Heitzer E, Ulz P, Belic J, Gutschi S, Quehenberger F, Fischereder K, Benezeder T, Auer M, Pischler C, Mannweiler S, Pichler M, Eisner F, Haeusler M, Riethdorf S, Pantel K, Samonigg H, Hoefler G, Augustin H, Geigl J, Speicher M
GENOME MED. 2013;5(4):30.

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee I, Lamszus K, Riethdorf S, Meyer-Staeckling S, Glatzel M, Matschke J, Witzel I, Westphal M, Brandt B, Müller V, Pantel K, Wikman H
AM J PATHOL. 2013;183(1):83-95.

Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling
Jiao B, Taniguchi-Ishigaki N, Güngör C, Peters M, Chen Y, Riethdorf S, Drung A, Ahronian L, Shin J, Pagnis R, Pantel K, Tachibana T, Lewis B, Johnsen S, Bach I
MOL BIOL CELL. 2013;24(19):3085-96.

Biologic challenges in the detection of circulating tumor cells.
Joosse S, Pantel K
CANCER RES. 2013;73(1):8-11.

Tumor cell dissemination: emerging biological insights from animal models and cancer patients
Kang Y, Pantel K
CANCER CELL. 2013;23(5):573-81.

Patterns of metastatic spread in early breast cancer
Klevesath M, Pantel K, Agbaje O, Provenzano E, Wishart G, Gough P, Pinder S, Duffy S, Purushotham A
BREAST. 2013;22(4):449-54.

Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions
Kluth M, Hesse J, Heinl A, Krohn A, Steurer S, Sirma H, Simon R, Mayer P, Schumacher U, Grupp K, Izbicki J, Pantel K, Dikomey E, Korbel J, Plass C, Sauter G, Schlomm T, Minner S
MODERN PATHOL. 2013;26(7):975-83.

Advances in circulating tumor cells (ACTC): from basic research to clinical practice
Lianidou E, Mavroudis D, Pantel K
BREAST CANCER RES. 2013;15(6):319.

Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.
Otto B, Gruner K, Heinlein C, Wegwitz F, Nollau P, Ylstra B, Pantel K, Schumacher U, Baumbusch L, Martin-Subero J, Siebert R, Wagener C, Streichert T, Deppert W, Tolstonog G
INT J CANCER. 2013;132(6):1300-1310.

Real-time liquid biopsy in cancer patients: fact or fiction?
Pantel K, Alix-Panabières C
CANCER RES. 2013;73(21):6384-8.

Tracking tumor resistance using 'liquid biopsies'
Pantel K, Diaz L, Polyak K
NAT MED. 2013;19(6):676-677.

Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
Schulze K, Gasch C, Staufer K, Nashan B, Lohse A, Pantel K, Riethdorf S, Wege H
INT J CANCER. 2013;133(9):2165-71.

CXCR7 expression in esophageal cancer
Tachezy M, Zander H, Gebauer F, Loga K, Pantel K, Izbicki J, Bockhorn M
J TRANSL MED. 2013;11:238.

C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
Uzunoglu F, Yavari N, Bohn B, Nentwich M, Reeh M, Pantel K, Perez D, Tsui T, Bockhorn M, Mann O, Izbicki J, Wikman H, Vashist Y
LUNG CANCER. 2013;81(1):123-9.

The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer.
Wallwiener M, Hartkopf A, Baccelli I, Riethdorf S, Schott S, Pantel K, Marmé F, Sohn C, Trumpp A, Rack B, Aktas B, Solomayer E, Müller V, Janni W, Schneeweiss A, Fehm T
BREAST CANCER RES TR. 2013;137(2):503-510.

Tumor metastasis: moving new biological insights into the clinic
Wan L, Pantel K, Kang Y
NAT MED. 2013;19(11):1450-64.

Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer
Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, Kling L, Vafaizadeh V, Sauter G, Terracciano L, Schumacher U, Pantel K, Assmann V
J BIOL CHEM. 2013;288(32):22993-3008.

Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
Yokobori T, Iinuma H, Shimamura T, Imoto S, Sugimachi K, Ishii H, Iwatsuki M, Ota D, Ohkuma M, Iwaya T, Nishida N, Kogo R, Sudo T, Tanaka F, Shibata K, Toh H, Sato T, Barnard G, Fukagawa T, Yamamoto S, Nakanishi H, Sasaki S, Miyano S, Watanabe T, Kuwano H, Mimori K, Pantel K, Mori M
CANCER RES. 2013;73(7):2059-69.

Circulating tumor cells and circulating tumor DNA.
Alix-Panabières C, Schwarzenbach H, Pantel K
ANNU REV MED. 2012;63:199-215.

The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination
Balz L, Bartkowiak K, Andreas A, Pantel K, Niggemann B, Zänker K, Brandt B, Dittmar T
J PATHOL. 2012;227(2):234-244.

The interrelating dynamics of hypoxic tumor microenvironments and cancer cell phenotypes in cancer metastasis.
Bartkowiak K, Riethdorf S, Pantel K
CANCER MICROENVIRON. 2012;5(1):59-72.

Plasticity of disseminating cancer cells in patients with epithelial malignancies.
Bednarz N, Alix-Panabières C, Pantel K
CANCER METAST REV. 2012;31(3-4):673-687.

Immunocytochemical detection and characterisation of individual micrometastatic tumour cells.
Braun S, Pantel K
Methods Mol Biol. 2012;878:63-70.

Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch L, Wrage M, Koops S, Glatzel M, Uzunoglu F, Kutup A, Hinsch A, Sauter G, Izbicki J, Pantel K, Wikman H
GENE CHROMOSOME CANC. 2012;51(6):618-629.

Zirkulierende Tumorzellen in Krebspatienten als neuer Biomarker
Gorges T, Riethdorf S, Pantel K
J Onkol - Z Onkol Fortb. 2012;(7):184-188.

Involvement of CXCR4 chemokine receptor in metastastic HER2-positive esophageal cancer.
Gros S, Kurschat N, Drenckhan A, Dohrmann T, Forberich E, Harms-Effenberger K, Reichelt U, Hoffman R, Pantel K, Kaifi J, Izbicki J
PLOS ONE. 2012;7(10):47287.

Disseminated tumor cells in pancreatic cancer-an independent prognosticator of disease progression and survival.
Harms-Effenberger K, Schröder C, Zu Eulenburg C, Reeh M, Tachezy M, Riethdorf S, Vashist Y, Izbicki J, Pantel K, Bockhorn M
INT J CANCER. 2012;131(4):475-483.

Minimal residual disease and circulating tumor cells in breast cancer: open questions for research.
Ignatiadis M, Sotiriou C, Pantel K
Recent Results Cancer Res. 2012;195:3-9.

Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells.
Joosse S, Hannemann J, Spötter J, Bauche A, Andreas A, Müller V, Pantel K
CLIN CANCER RES. 2012;18(4):993-1003.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K
J PATHOL. 2012;226(4):674-686.

Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer.
Madhavan D, Zucknick M, Wallwiener M, Cuk K, Modugno C, Scharpff M, Schott S, Heil J, Turchinovich A, Yang R, Benner A, Riethdorf S, Trumpp A, Sohn C, Pantel K, Schneeweiss A, Burwinkel B
CLIN CANCER RES. 2012;18(21):5972-5982.

High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.
Mathiesen R, Fjelldal R, Liestøl K, Due E, Geigl J, Riethdorf S, Borgen E, Rye I, Schneider I, Obenauf A, Mauermann O, Nilsen G, Ole C, Børresen-Dale A, Pantel K, Speicher M, Naume B, Baumbusch L
INT J CANCER. 2012;131(4):405-415.

Prognostic impact of circulating tumor cells assessed with the CellSearch System™ and AdnaTest Breast™ in metastatic breast cancer patients: the DETECT study.
Müller V, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Pantel K, Fehm T, Group O
BREAST CANCER RES. 2012;14(4):118.

Detection methods of circulating tumor cells.
Pantel K, Alix-Panabières C
J THORAC DIS. 2012;4(5):446-447.

The potential of circulating tumor cells as a liquid biopsy to guide therapy in prostate cancer.
Pantel K, Alix-Panabières C
CANCER DISCOV. 2012;2(11):974-975.

Circulating epithelial cells in patients with benign colon diseases.
Pantel K, Denève E, Nocca D, Coffy A, Vendrell J, Maudelonde T, Riethdorf S, Alix-Panabières C
CLIN CHEM. 2012;58(5):936-940.

Considerations in the development of circulating tumor cell technology for clinical use.
Parkinson D, Dracopoli N, Petty B, Compton C, Cristofanilli M, Deisseroth A, Hayes D, Kapke G, Kumar P, Lee J, Liu M, McCormack R, Mikulski S, Nagahara L, Pantel K, Pearson-White S, Punnoose E, Roadcap L, Schade A, Scher H, Sigman C, Kelloff G
J TRANSL MED. 2012;10:138.

Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.
Rink M, Chun F, Dahlem R, Soave A, Minner S, Hansen J, Stoupiec M, Coith C, Kluth L, Ahyai S, Friedrich M, Shariat S, Fisch M, Pantel K, Riethdorf S
EUR UROL. 2012;61(4):810-817.

Low levels of cell-free circulating miR-361-3p and miR-625* as blood-based markers for discriminating malignant from benign lung tumors.
Roth C, Stückrath I, Pantel K, Izbicki J, Tachezy M, Schwarzenbach H
PLOS ONE. 2012;7(6):38248.

The current role of circulating tumor cells in the diagnosis and management of bone metastases in advanced prostate cancer.
Saad F, Pantel K
FUTURE ONCOL. 2012;8(3):321-331.

VEGFR-1 expression levels predict occurrence of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma
Schultze A, Ben-Batalla I, Riethdorf S, Bubenheim M, Yekebas E, Erbersdobler A, Reichelt U, Harms-Effenberger K, Schmidt T, Izbicki J, Bokemeyer C, Pantel K, Fiedler W, Loges S
CLIN EXP METASTAS. 2012;29(8):879-887.

Loss of heterozygosity at tumor suppressor genes detectable on fractionated circulating cell-free tumor DNA as indicator of breast cancer progression.
Schwarzenbach H, Eichelser C, Kropidlowski J, Janni W, Rack B, Pantel K
CLIN CANCER RES. 2012;18(20):5719-5730.

Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients.
Schwarzenbach H, Milde-Langosch K, Steinbach B, Müller V, Pantel K
BREAST CANCER RES TR. 2012;134(3):933-941.

The connectivity of lymphogenous and hematogenous tumor cell dissemination: biological insights and clinical implications.
Sleeman J, Cady B, Pantel K
CLIN EXP METASTAS. 2012;29(7):737-746.

ALCAM (CD166) expression and serum levels are markers for poor survival of esophageal cancer patients
Tachezy M, Harms-Effenberger K, Zander H, Minner S, Gebauer F, Vashist Y, Sauter G, Pantel K, Izbicki J, Bockhorn M
INT J CANCER. 2012;131(2):396-405.

Circulating tumor-derived biomarkers in lung cancer.
Tänzer A, Alix-Panabières C, Wikman H, Pantel K
J THORAC DIS. 2012;4(5):448-449.

Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu F, Kaufmann C, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, Pantel K, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN SURG ONCOL. 2012;19(7):2159-2168.

Disseminated tumor cells in bone marrow and the natural course of resected esophageal cancer.
Vashist Y, Harms-Effenberger K, Vettorazzi E, Riethdorf S, Yekebas E, Izbicki J, Pantel K
ANN SURG. 2012;255(6):1105-1112.

Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K
BREAST CANCER RES. 2012;14(2):49.

Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman H, Sielaff-Frimpong B, Kropidlowski J, Witzel I, Milde-Langosch K, Sauter G, Westphal M, Lamszus K, Pantel K
PLOS ONE. 2012;7(10):47537.

Meta-analysis of the prognostic value of circulating tumor cells in breast cancer.
Zhang L, Riethdorf S, Wu G, Wang T, Yang K, Peng G, Liu J, Pantel K
CLIN CANCER RES. 2012;18(20):5701-5710.

Clinical relevance and biology of circulating tumor cells.
Bednarz N, Alix-Panabières C, Pantel K
BREAST CANCER RES. 2011;13(6):228.

Circulating tumors cells as biomarkers: progress toward biomarker qualification.
Danila D, Pantel K, Fleisher M, Scher H
CANCER J. 2011;17(6):438-450.

Circulating cancer cells and their clinical applications.
Diamandis E, Pantel K, Scher H, Terstappen L, Lianidou E
CLIN CHEM. 2011;57(11):1478-1484.

Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells
Grabinski N, Bartkowiak K, Grupp K, Brandt B, Pantel K, Jücker M
CELL SIGNAL. 2011;23(12):1952-1960.

Quantitative high-resolution genomic analysis of single cancer cells.
Hannemann J, Meyer-Staeckling S, Kemming D, Alpers I, Joosse S, Pospisil H, Kurtz S, Görndt J, Püschel K, Riethdorf S, Pantel K, Brandt B
PLOS ONE. 2011;6(11):26362.

Detection and clinical relevance of early disseminated breast cancer cells depend on their cytokeratin expression pattern.
Harms-Effenberger K, Borgen E, Zu Eulenburg C, Bartkowiak K, Grosser A, Synnestvedt M, Kaaresen R, Brandt B, Nesland J, Pantel K, Naume B
BREAST CANCER RES TR. 2011;125(3):729-738.

Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein S, Müller V, Köhler N, Wikman H, Krenkel S, Streichert T, Schweizer M, Riethdorf S, Assmann V, Henningsen M, Beck K, Issa R, Jänicke F, Pantel K, Milde-Langosch K
BREAST CANCER RES TR. 2011;129(2):347-360.

Molecular mechanisms of metastasis.
Hoon D, Ferris R, Tanaka R, Chong K, Alix-Panabières C, Pantel K
J SURG ONCOL. 2011;103(6):508-517.

Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis.
Janni W, Vogl F, Wiedswang G, Synnestvedt M, Fehm T, Jückstock J, Borgen E, Rack B, Braun S, Sommer H, Solomayer E, Pantel K, Nesland J, Friese K, Naume B
CLIN CANCER RES. 2011;17(9):2967-2976.

The anti-interleukin-6 antibody siltuximab down-regulates genes implicated in tumorigenesis in prostate cancer patients from a phase I study.
Karkera J, Steiner H, Li W, Skradski V, Moser P, Riethdorf S, Reddy M, Puchalski T, Safer K, Prabhakar U, Pantel K, Qi M, Culig Z
PROSTATE. 2011;71(13):1455-1465.

Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.
Kornfeld J, Meder S, Wohlberg M, Friedrich R, Rau T, Riethdorf L, Löning T, Pantel K, Riethdorf S
BRIT J CANCER. 2011;104(1):138-145.

VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors.
Lu X, Mu E, Wei Y, Riethdorf S, Yang Q, Yuan M, Yan J, Hua Y, Tiede B, Lu X, Haffty B, Pantel K, Massagué J, Kang Y
CANCER CELL. 2011;20(6):701-714.

ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
Minner S, Enodien M, Sirma H, Lübke A, Krohn A, Mayer P, Simon R, Tennstedt P, Müller J, Scholz L, Brase J, Liu A, Schlüter H, Pantel K, Schumacher U, Bokemeyer C, Steuber T, Graefen M, Sauter G, Schlomm T
CLIN CANCER RES. 2011;17(18):5878-5888.

Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer.
Müller V, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Zeitz J, Pantel K, Fehm T, Group D
BREAST CANCER RES. 2011;13(4):71.

Prospective multi-centre study to validate chromogenic in situ hybridisation for the assessment of HER2 gene amplification in specimens from adjuvant and metastatic breast cancer patients.
Riethdorf S, Hoegel B, John B, Ott G, Fritz P, Thon S, Löning T, Pantel K
J CANCER RES CLIN. 2011;137(2):261-269.

Detection of circulating tumour cells in peripheral blood of patients with advanced non-metastatic bladder cancer.
Rink M, Chun F, Minner S, Friedrich M, Mauermann O, Heinzer H, Huland H, Fisch M, Pantel K, Riethdorf S
BJU INT. 2011;107(10):1668-1675.

Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer.
Roth C, Kasimir-Bauer S, Pantel K, Schwarzenbach H
MOL ONCOL. 2011;5(3):281-291.

Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression.
Roth C, Pantel K, Müller V, Rack B, Kasimir-Bauer S, Janni W, Schwarzenbach H
BMC CANCER. 2011;11:4.

Circulating microRNAs: promising breast cancer biomarkers - author´s response
Roth C, Rack B, Müller V, Janni W, Pantel K, Schwarzenbach H
BREAST CANCER RES. 2011;13(1):403.

Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ.
Sänger N, Harms-Effenberger K, Riethdorf S, Viviane V, Gauwerky J, Wiegratz I, Strebhardt K, Kaufmann M, Pantel K
INT J CANCER. 2011;129(10):2522-2526.

Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
Schwarzenbach H, Chun F, Isbarn H, Huland H, Pantel K
J CANCER RES CLIN. 2011;137(5):811-819.

Cell-free nucleic acids as biomarkers in cancer patients.
Schwarzenbach H, Hoon D, Pantel K
NAT REV CANCER. 2011;11(6):426-437.

Evaluation of cell-free tumour DNA and RNA in patients with breast cancer and benign breast disease.
Schwarzenbach H, Müller V, Milde-Langosch K, Steinbach B, Pantel K
MOL BIOSYST. 2011;7(10):2848-2854.

Controversies in clinical cancer dormancy.
Uhr J, Pantel K
P NATL ACAD SCI USA. 2011;108(30):12396-12400.

Circulating tumor cell isolation and diagnostics: toward routine clinical use.
van de Stolpe A, Pantel K, Sleijfer S, Terstappen L, Toonder d, Jaap M
CANCER RES. 2011;71(18):5955-5960.

The GNAS1 T393C single nucleotide polymorphism predicts the natural postoperative course of complete resected esophageal cancer.
Vashist Y, Kutup A, Musici S, Yekebas E, Mina S, Uzunoglu F, Zehler O, König A, Cataldegirmen G, Bockhorn M, Harms-Effenberger K, Kalinin V, Pantel K, Izbicki J
MOL CELL ONCOL. 2011;34(4):281-288.

Impact of platinum-based chemotherapy on circulating nucleic acid levels, protease activities in blood and disseminated tumor cells in bone marrow of ovarian cancer patients.
Wimberger P, Roth C, Pantel K, Kasimir-Bauer S, Kimmig R, Schwarzenbach H
INT J CANCER. 2011;128(11):2572-2580.

Detection of circulating tumor cells by RT-PCR significantly associated with poor prognosis in breast cancer.
Zhang L, Wu G, Pantel K
BREAST CANCER RES TR. 2011;130(1):359-364.

Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Bartkowiak K, Harms-Effenberger K, Harder S, Andreas A, Buck F, Peter-Katalinic J, Pantel K, Brandt B
J PROTEOME RES. 2010;9(6):3158-3168.

BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood
Bednarz N, Eltze E, Semjonow A, Rink M, Andreas A, Mulder L, Hannemann J, Fisch M, Pantel K, Weier H, Bielawski K, Brandt B
CLIN CANCER RES. 2010;16(13):3340-3348.

HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial.
Fehm T, Müller V, Aktas B, Janni W, Schneeweiss A, Stickeler E, Lattrich C, Löhberg C, Solomayer E, Rack B, Riethdorf S, Klein C, Schindlbeck C, Brocker K, Kasimir-Bauer S, Wallwiener D, Pantel K
BREAST CANCER RES TR. 2010;124(2):403-412.

Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus.
Kalinina T, Bockhorn M, Kaifi J, Thieltges S, Güngör C, Harms-Effenberger K, Strelow A, Reichelt U, Sauter G, Pantel K, Izbicki J, Yekebas E
INT J CANCER. 2010;127(8):1931-1940.

What's new on circulating tumor cells? A meeting report.
Lianidou E, Mavroudis D, Sotiropoulou G, Agelaki S, Pantel K
BREAST CANCER RES. 2010;12(4):307.

Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications.
Müller I, Wischnewski F, Pantel K, Schwarzenbach H
BMC CANCER. 2010;10:297.

Insights into minimal residual disease in cancer patients: implications for anti-cancer therapies.
Müller V, Alix-Panabières C, Pantel K
EUR J CANCER. 2010;46(7):1189-1197.

Circulating tumour cells in cancer patients: challenges and perspectives.
Pantel K, Alix-Panabières C
TRENDS MOL MED. 2010;16(9):398-406.

Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial.
Riethdorf S, Müller V, Zhang L, Rau T, Loibl S, Komor M, Roller M, Huober J, Fehm T, Schrader I, Hilfrich J, Holms F, Tesch H, Eidtmann H, Untch M, von Minckwitz G, Pantel K
CLIN CANCER RES. 2010;16(9):2634-2645.

Advancing personalized cancer therapy by detection and characterization of circulating carcinoma cells.
Riethdorf S, Pantel K
ANN NY ACAD SCI. 2010;1210:66-77.

Increase in circulating microRNA levels in blood of ovarian cancer patients
Roth C, Kasimir-Bauer S, Heubner M, Pantel K, Schwarzenbach H
2010. Circulating nucleic acids in plasma and serum. Gahan P (Hrsg.). 1.. Aufl. Springer, 63-71.

Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer.
Roth C, Rack B, Müller V, Janni W, Pantel K, Schwarzenbach H
BREAST CANCER RES. 2010;12(6):90.

Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
Schwarzenbach H, Goekkurt E, Pantel K, Aust D, Stoehlmacher J
INT J CANCER. 2010;127(4):881-888.

PSA and Prostate
Schwarzenbach H, Pantel K
2010. PSA and Prostate. Nova Science Publishers, 65-85.

Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer.
Alix-Panabières C, Vendrell J, Slijper M, Pellé O, Barbotte E, Mercier G, Jacot W, Fabbro M, Pantel K
BREAST CANCER RES. 2009;11(3):39.

Two-dimensional differential gel electrophoresis of a cell line derived from a breast cancer micrometastasis revealed a stem/ progenitor cell protein profile.
Bartkowiak K, Wieczorek M, Buck F, Harder S, Moldenhauer J, Harms-Effenberger K, Pantel K, Peter-Katalinic J, Brandt B
J PROTEOME RES. 2009;8(4):2004-2014.

Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer.
Johnsen S, Güngör C, Prenzel T, Riethdorf S, Riethdorf L, Taniguchi-Ishigaki N, Rau T, Tursun B, Furlow J, Sauter G, Scheffner M, Pantel K, Gannon F, Bach I
CANCER RES. 2009;69(1):128-136.

Strong impact of micrometastatic tumor cell load in patients with esophageal carcinoma.
König A, Prenzel K, Bogoevski D, Yekebas E, Bubenheim M, Faithova L, Vashist Y, Gawad K, Baldus S, Pantel K, Schneider P, Hölscher A, Izbicki J
ANN SURG ONCOL. 2009;16(2):454-462.

Clinical Relevance of Disseminated Tumor Cells in Bone Marrow and Circulating Tumor Cells in the Blood of Breast Cancer Patients
Müller V, Fehm T, Janni W, Gebauer G, Solomayer E, Pantel K
BREAST CARE. 2009;4(5):333-338.

Cancer micrometastases.
Pantel K, Alix-Panabières C, Riethdorf S
NAT REV CLIN ONCOL. 2009;6(6):339-351.

Pathology: are circulating tumor cells predictive of overall survival?
Pantel K, Riethdorf S
NAT REV CLIN ONCOL. 2009;6(4):190-191.

Detection and Characterization of Disseminated Tumor Cells present in Bone Marrow of Cancer Patients
Riethdorf S, Müller V, Alix-Panabières C, Pantel K
2009. Bone and Cancer. Springer London: 103-117.

Clinical relevance and current challenges of research on disseminating tumor cells in cancer patients.
Riethdorf S, Pantel K
BREAST CANCER RES. 2009;11(3):10.

Bone marrow aspiration for disseminated tumor cell detection: a must-have test or is the jury still out?
Scher H, Pantel K
J CLIN ONCOL. 2009;27(10):1531-1533.

Cell-free tumor DNA in blood plasma as a marker for circulating tumor cells in prostate cancer.
Schwarzenbach H, Alix-Panabières C, Müller I, Letang N, Vendrell J, Rebillard X, Pantel K
CLIN CANCER RES. 2009;15(3):1032-1038.

Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer.
Schwarzenbach H, Pantel K, Kemper B, Beeger C, Otterbach F, Kimmig R, Kasimir-Bauer S
BREAST CANCER RES. 2009;11(5):71.

Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment.
Slade M J, Payne R, Riethdorf S, Ward B, Zaidi S A, Stebbing J, Palmieri C, Sinnett H, Kulinskaya E, Pitfield T, McCormack R, Pantel K, Coombes R
BRIT J CANCER. 2009;100(1):160-166.

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage M, Ruosaari S, Eijk P, Kaifi J, Hollmén J, Yekebas E, Izbicki J, Brakenhoff R, Streichert T, Riethdorf S, Glatzel M, Ylstra B, Pantel K, Wikman H
CLIN CANCER RES. 2009;15(5):1566-1574.

Circulating tumor cells and bone marrow micrometastasis.
Alix-Panabières C, Riethdorf S, Pantel K
CLIN CANCER RES. 2008;14(16):5013-5021.

Elevated expression of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is associated with increased angiogenic potential in non-small-cell lung cancer.
Dango S, Sienel W, Schreiber M, Stremmel C, Kirschbaum A, Pantel K, Passlick B
LUNG CANCER. 2008;60(3):426-433.

Micrometastatic spread in breast cancer: detection, molecular characterization and clinical relevance.
Fehm T, Müller V, Alix-Panabières C, Pantel K
BREAST CANCER RES. 2008;10(1):1.

Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.
Köllermann J, Weikert S, Schostak M, Kempkensteffen C, Kleinschmidt K, Rau T, Pantel K
J CLIN ONCOL. 2008;26(30):4928-4933.

Identification of loss of heterozygosity on circulating free DNA in peripheral blood of prostate cancer patients: potential and technical improvements.
Müller I, Beeger C, Alix-Panabières C, Rebillard X, Pantel K, Schwarzenbach H
CLIN CHEM. 2008;54(4):688-696.

HER2 as marker for the detection of circulating tumor cells.
Müller V, Pantel K
BREAST CANCER RES TR. 2008.

Detection, clinical relevance and specific biological properties of disseminating tumour cells.
Pantel K, Brakenhoff R, Brandt B
NAT REV CANCER. 2008;8(5):329-340.

Disseminated tumor cells in bone marrow and circulating tumor cells in blood of breast cancer patients: current state of detection and characterization.
Riethdorf S, Pantel K
PATHOBIOLOGY. 2008;75(2):140-148.

Review: Biological relevance of disseminated tumor cells in cancer patients.
Riethdorf S, Wikman H, Pantel K
INT J CANCER. 2008;123(9):1991-2006.

A comparative study of tissue inhibitor of metalloproteinases-1 levels in plasma and tumour tissue from patients with primary breast cancer and in plasma from patients with metastatic breast cancer.
Schrohl A, Müller V, Christensen I, Pantel K, Thomssen C, Bruenner N
TUMOR BIOL. 2008;29(3):181-187.

Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer.
Schwarzenbach H, Chun F, Müller I, Seidel C, Urban K, Erbersdobler A, Huland H, Pantel K, Friedrich M
BJU INT. 2008;102(2):253-258.

Methods of cancer diagnosis, therapy and prognosis
Schwarzenbach H, Pantel K
2008. Methods of cancer diagnosis, therapy and prognosis. Springer, 481-497.

Detection and monitoring of cell-free DNA in blood of patients with colorectal cancer.
Schwarzenbach H, Stoehlmacher J, Pantel K, Goekkurt E
ANN NY ACAD SCI. 2008;1137:190-196.

Cancer micrometastasis and tumour dormancy.
Wikman H, Vessella R, Pantel K
APMIS. 2008;116(7-8):754-770.

Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.
Zafrakas M, Tarlatzis B, Streichert T, Pournaropoulos F, Wölfle U, Smeets S, Wittek B, Grimbizis G, Brakenhoff R, Pantel K, Bontis J, Günes C
INT J MOL MED. 2008;21(3):335-344.

Current status in human breast cancer micrometastasis.
Alix-Panabières C, Müller V, Pantel K
CURR OPIN ONCOL. 2007;19(6):558-563.

Detection and characterization of putative metastatic precursor cells in cancer patients.
Alix-Panabières C, Vendrell J, Pellé O, Rebillard X, Riethdorf S, Müller V, Fabbro M, Pantel K
CLIN CHEM. 2007;53(3):537-539.

Lymph node micrometastases in lung cancer.
Harms-Effenberger K, Sienel W, Pantel K
Cancer Treat Res. 2007;135:167-175.

Short tandem repeat polymorphism in exon 4 of esophageal cancer-related gene 2 detected in genomic DNA is a prognostic marker for esophageal cancer.
Kaifi J, Rawnaq T, Schurr P, Yekebas E, Mann O, Merkert P, Link B, Kalinin V, Pantel K, Sauter G, Strate T, Izbicki J
AM J SURG. 2007;194(3):380-384.

L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.
Kaifi J, Reichelt U, Quaas A, Schurr P, Wachowiak R, Yekebas E, Strate T, Schneider C, Pantel K, Schachner M, Sauter G, Izbicki J
MODERN PATHOL. 2007;20(11):1183-1190.

Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis.
Loges S, Clausen H, Reichelt U, Bubenheim M, Erbersdobler A, Schurr P, Yekebas E, Schuch G, Izbicki J, Pantel K, Bokemeyer C, Fiedler W
CLIN CANCER RES. 2007;13(1):76-80.

The clinical significance of circulating tumor cells.
Pantel K, Alix-Panabières C
NAT REV CLIN ONCOL. 2007;4(2):62-63.

Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.
Riethdorf S, Fritsche H, Müller V, Rau T, Schindlbeck C, Rack B, Janni W, Coith C, Beck K, Jänicke F, Jackson S, Gornet T, Cristofanilli M, Pantel K
CLIN CANCER RES. 2007;13(3):920-928.

Central mesenteric lymph node BER-Ep4+ cells in colorectal cancer: challenge to sentinel node concept?
Schurr P, Behnke S, Kaifi J, Bogoevski D, Link B, Mann O, Strate T, Pantel K, Izbicki J, Yekebas E
DIGEST SURG. 2007;24(1):19-27.

Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancer.
Schwarzenbach H, Chun F, Lange I, Carpenter S, Gottberg M, Erbersdobler A, Friedrich M, Huland H, Pantel K
INT J CANCER. 2007;120(7):1465-1471.

A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer.
Schwarzenbach H, Müller V, Beeger C, Gottberg M, Stahmann N, Pantel K
BREAST CANCER RES. 2007;9(5):66.

Detection of MAGE-A transcripts in bone marrow is an independent prognostic factor in operable non-small-cell lung cancer.
Sienel W, Mecklenburg I, Dango S, Ehrhardt P, Kirschbaum A, Passlick B, Pantel K
CLIN CANCER RES. 2007;13(13):3840-3847.

Tumor cell dormancy: an NCI workshop report.
Vessella R, Pantel K, Mohla S
CANCER BIOL THER. 2007;6(9):1496-1504.

Microsatellite analysis in serum DNA as a diagnostic tool for distinction of patients with unknown pancreatic masses.
Wachowiak R, Kaifi J, Schwarzenbach H, Yekebas E, Merkert P, Schurr P, Hansen B, Reichelt U, Strate T, Pantel K, Izbicki J
DIAGN MOL PATHOL. 2007;16(3):174-178.

Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.
Wischnewski F, Friese O, Pantel K, Schwarzenbach H
MOL CANCER RES. 2007;5(7):749-759.

The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence
Janni W, Rack B, Schindlbeck C, Strobl B, Rjosk D, Braun S, Sommer H, Pantel K, Gerber B, Friese K
CANCER-AM CANCER SOC. 2005;103(5):884-91.

Sentinel Lymph Node Dissection and Micrometastasis Detection in Bone Marrow and Lymph Nodes: Molecular Oncology of Breast Cancer
Müller V, Kasimir-Bauer S, Pantel K
2004. Molecular Oncology of Breast Cancer. Ross J, Hortobagyi G (Hrsg.). Jones and Bartlett, 117-127.

Detection and characterization of circulating microsatellite-DNA in blood of patients with breast cancer
Schwarzenbach H, Müller V, Stahmann N, Pantel K
ANN NY ACAD SCI. 2004;1022:25-32.

Detection and characterisation of occult metastatic cells in bone marrow of breast cancer patients: Micrometastasis
Braun S, Müller V, Pantel K
2003. Micrometastasis. Pantel K (Hrsg.). Kluwer Academic Press, 47-66.

Comparative evaluation of urokinase-type plasminogen activator receptor expression in primary breast carcinomas and on metastatic tumor cells
Hemsen A, Riethdorf L, Brünner N, Berger J, Ebel S, Thomssen C, Jänicke F, Pantel K
INT J CANCER. 2003;107(6):903-9.

Clinical Relevance of Micrometastatic Disease in Patients with Solid Tumors
Muller V, Pantel K
AM J CANCER. 2003;2(2):77-86.

Correlation on serum HER-2/neu extracellular domain levels in metastatic breast cancer with the expression of HER-2/neu determined by immunohistochemistry in primary tumors
Witzel I, Thomssen C, Pantel K, Neumann R, Carney W, Loening T, Jaenicke F, Müller V
BREAST CANCER RES TR. 2003;82, Suppl. 1:S 143.

Letzte Aktualisierung aus dem FIS: 24.04.2025 - 00:33 Uhr

Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients
Bartkowiak K, Mohammadi P, Nissen P, Werner S, Agorku D, Andreas A, Geffken M, Peine S, Verpoort K, Deutsch T, Michel L, Schneeweiss A, Thewes V, Trumpp A, Hardt O, Müller V, Riethdorf S, Schlüter H, Pantel K
SCI REP-UK. 2025;15(1):3913.

Lessons (to be) learned from liquid biopsies: assessment of circulating cells and cell-free DNA in cancer and pregnancy-acquired microchimerism
Bergmann L, Afflerbach A, Yuan T, Pantel K, Smit D
SEMIN IMMUNOPATHOL. 2025;47(1):14.

Identification and characterization of tumor and stromal derived liquid biopsy analytes in pancreatic ductal adenocarcinoma
Götze J, Meißner K, Pereira-Veiga T, Belloum Y, Schneegans S, Kropidlowski J, Gorgulho J, Busch A, Honselmann K, Schönrock M, Putscher A, Peine S, Nitschke C, Simon R, Spindler V, Izbicki J, Hackert T, Bokemeyer C, Pantel K, Uzunoglu F, Sinn M, Wikman H
J EXP CLIN CANC RES. 2025;44(1):14.

Improved survival of advanced melanoma patients receiving immunotherapy with concomitant antithrombotic therapy - A multicenter study on 2419 patients from the prospective skin cancer registry ADOReg
Kött J, Zell T, Zimmermann N, Rünger A, Smit D, Abeck F, Geidel G, Hansen-Abeck I, Heidrich I, Weichenthal M, Ugurel S, Leiter U, Berking C, Gutzmer R, Schadendorf D, Zimmer L, Livingstone E, Wasielewski I, Mohr P, Meier F, Haferkamp S, Drexler K, Herbst R, Kellner I, Utikal J, Wohlfeil S, Pföhler C, Adam L, Meiss F, Möbes M, Welzel J, Schilling B, Ziller F, Kaatz M, Kreuter A, Sindrilaru A, Dippel E, Sachse M, Weishaupt C, Hüning S, Heinzerling L, Loquai C, Bauer A, Schneider S, Gebhardt C
EUR J CANCER. 2025;214:115159.

Bemcentinib as monotherapy and in combination with low-dose cytarabine in acute myeloid leukemia patients unfit for intensive chemotherapy: a phase 1b/2a trial
Loges S, Heuser M, Chromik J, Sutamtewagul G, Kapp-Schwoerer S, Crugnola M, Di Renzo N, Lemoli R, Mattei D, Fiedler W, Alvarado-Valero Y, Ben-Batalla I, Waizenegger J, Rieckmann L, Janning M, Collienne M, Imbusch C, Beumer N, Micklem D, H Nilsson L, Madeleine N, McCracken N, Oliva C, Gorcea-Carson C, Gjertsen B
NAT COMMUN. 2025;16(1):2846.

Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition
Melzer Y, Fergen N, Mess C, Stadler J, Geidel G, Schwietzer Y, Kött J, Pantel K, Schneider S, Utikal J, Wladykowski E, Vidal-Y-Sy S, Bauer A, Gebhardt C
TRANSL ONCOL. 2025;52:102224.

Breaking up clusters of circulating tumour cells to halt cancer spread
Smit D, Pantel K
NATURE. 2025;638(8050):329-330.

Incidental Findings of Maternal Cancer in Noninvasive Prenatal Testing through Cell-Free DNA Sequencing
Smit D, Pantel K
CLIN CHEM. 2025 [Epub ahead of print].

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model
Smit D, Pereira-Veiga T, Brauer H, Horn M, Nissen P, Mair T, Siebels B, Voß H, Zhuang R, Haider M, Loreth D, Iskhakova M, Lindemann B, Kött J, Cayrefourcq L, Wellbrock J, Schlüter H, Pantel K, Alix-Panabières C, Jücker M
MOL ONCOL. 2025 [Epub ahead of print].

Cancer-associated fibroblasts as a potential novel liquid biopsy marker in cancer patients
Weber F, Reese K, Pantel K, Smit D
J EXP CLIN CANC RES. 2025;44(1):.

Nanopore sequencing from formalin-fixed paraffin-embedded specimens for copy-number profiling and methylation-based CNS tumor classification
Afflerbach A, Albers A, Appelt A, Schweizer L, Paulus W, Bockmayr M, Schüller U, Thomas C
ACTA NEUROPATHOL. 2024;147(1):.

Two decades of advances in clinical oncology - lessons learned and future directions
Banerjee S, Booth C, Bruera E, Büchler M, Drilon A, Fry T, Ghobrial I, Gianni L, Jain R, Kroemer G, Llovet J, Long G, Pantel K, Pritchard-Jones K, Scher H, Tabernero J, Weichselbaum R, Weller M, Wu Y
NAT REV CLIN ONCOL. 2024;21(11):771-780.

Expression profiling by high-throughput sequencing reveals GADD45, SMAD7, EGR-1 and HOXA3 activation in Myostatin (MSTN) and GDF11 treated myoblasts
Braun P, Alawi M, Saygi C, Pantel K, Wagers A
GENET MOL BIOL. 2024;47(2):e20230304.

Thymic Atrophy and Immune Dysregulation in Infants with Complex Congenital Heart Disease
Bremer S, Boxnick A, Glau L, Biermann D, Joosse S, Thiele F, Billeb E, May J, Kolster M, Hackbusch R, Fortmann M, Kozlik-Feldmann R, Hübler M, Tolosa E, Sachweh J, Gieras A
J CLIN IMMUNOL. 2024;44(3):.

Circulating Tumor Cells: From Basic to Translational Research
Cortés-Hernández L, Eslami-S Z, Pantel K, Alix-Panabières C
CLIN CHEM. 2024;70(1):81-89.

Relationship of Ki-67 index in biopsies of metastatic breast cancer tissue and circulating tumor cells (CTCs) at the time of biopsy collection
Deutsch T, Fischer C, Riedel F, Haßdenteufel K, Michel L, Sütterlin M, Riethdorf S, Pantel K, Wallwiener M, Schneeweiss A, Stefanovic S
ARCH GYNECOL OBSTET. 2024;309(1):235-248.

Applications of Nanopore sequencing in precision cancer medicine
Dyshlovoy S, Paigin S, Afflerbach A, Lobermeyer A, Werner S, Schüller U, Bokemeyer C, Schuh A, Bergmann L, von Amsberg G, Joosse S
INT J CANCER. 2024;155(12):2129-2140.

Efficacy of Lapatinib in Patients with HER2-Negative Metastatic Breast Cancer and HER2-Positive Circulating Tumor Cells-The DETECT III Clinical Trial
Fehm T, Mueller V, Banys-Paluchowski M, Fasching P, Friedl T, Hartkopf A, Huober J, Loehberg C, Rack B, Riethdorf S, Schneeweiss A, Wallwiener D, Meier-Stiegen F, Krawczyk N, Jaeger B, Reinhardt F, Hoffmann O, Mueller L, Wimberger P, Ruckhaeberle E, Blohmer J, Cieslik J, Franken A, Niederacher D, Neubauer H, Pantel K, Janni W
CLIN CHEM. 2024;70(1):307-318.

Differential predictive value of tissue-specific PD-L1 expression scores in adjuvant immunotherapy of melanoma
Geidel G, Parnian N, Meß C, Schlepper N, Rünger A, Heidrich I, Hansen I, Smit D, Menz A, Pantel K, Schneider S, Kött J, Gebhardt C
J EUR ACAD DERMATOL. 2024;38(10):2017-2023.

Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, Mertens H, Węglarz A, Sander S, Chojnowski G, Wikman H, Ohlenschläger O, von Amsberg G, Pantel K, Wilmanns M
NAT COMMUN. 2024;15(1):.

Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy
Gorgulho J, Loosen S, Masood R, Giehren F, Pagani F, Buescher G, Kocheise L, Joerg V, Schmidt C, Schulze K, Roderburg C, Kinkel E, Fritzsche B, Wehmeyer S, Schmidt B, Kachel P, Rolling C, Götze J, Busch A, Sinn M, Pereira-Veiga T, Wikman H, Geffken M, Peine S, Matschl U, Altfeld M, Huber S, Lohse A, Beier F, Brümmendorf T, Bokemeyer C, Luedde T, von Felden J
J EXP CLIN CANC RES. 2024;43(1):298.

Liquid Biopsy – Ein neues diagnostisches Konzept in der Onkologie
Heidrich I, Roeper C, Rautmann C, Pantel K, Smit D
LARYNGO RHINO OTOL. 2024;103(1):40-46.

Detection of Multiple HPV Types in Liquid Biopsies of Cervical Neoplasia
Herbst J, Vohl V, Krajina M, Leffers M, Kropidlowski J, Prieske K, Jaeger A, Oliveira-Ferrer L, Schmalfeldt B, Goy Y, Burandt E, Pantel K, Vollmert C, Sartori A, Woelber L, Effenberger K, Wikman H
CLIN CHEM. 2024;70(1):285-296.

Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO)
Holz A, Obi N, Ahrens W, Berger K, Bohn B, Brenner H, Fischer B, Fricke J, Führer A, Gastell S, Greiser K, Harth V, Heise J, Holleczek B, Keil T, Klett-Tammen C, Leitzmann M, Lieb W, Meinke-Franze C, Michels K, Mikolajczyk R, Nimptsch K, Peters A, Pischon T, Riedel O, Schikowski T, Schipf S, Schmidt B, Schulze M, Stang A, Hellwig K, Riemann-Lorenz K, Heesen C, Becher H
BMC NEUROL. 2024;24(1):123.

Iodinated PSMA Ligands as XFI Tracers for Targeted Cell Imaging and Characterization of Nanoparticles
Kerpa S, Holzapfel M, Staufer T, Kuhrwahl R, Mutas M, Werner S, Schulze V, Nakielski P, Feliu N, Oetjen E, Haak J, Ziegler F, Buchin R, Han J, Parak W, Grüner F, Maison W
INT J MOL SCI. 2024;25(22):.

High Serum Levels of CCL20 Are Associated with Recurrence and Unfavorable Overall Survival in Advanced Melanoma Patients Receiving Immunotherapy
Kött J, Hoehne I, Heidrich I, Zimmermann N, Reese K, Zell T, Geidel G, Rünger A, Schneider S, Pantel K, Smit D, Gebhardt C
CANCERS. 2024;16(9):.

C-reactive protein flare predicts response to checkpoint inhibitor treatment in melanoma
Kött J, Zimmermann N, Zell T, Heidrich I, Geidel G, Rünger A, Smit D, Merkle M, Parnian N, Hansen I, Hoehne I, Abeck F, Torster L, Weichenthal M, Pantel K, Schneider S, Gebhardt C
J EUR ACAD DERMATOL. 2024;38(8):1575–1587.

Sentinel lymph node risk prognostication in primary cutaneous melanoma through tissue-based profiling, potentially redefining the need for sentinel lymph node biopsy
Kött J, Zimmermann N, Zell T, Rünger A, Heidrich I, Geidel G, Smit D, Hansen I, Abeck F, Schadendorf D, Eggermont A, Puig S, Hauschild A, Gebhardt C
EUR J CANCER. 2024;202:.

PIK3CA Hotspot Mutations in Saliva as a Diagnostic Marker in Oral Squamous Cell Carcinoma Patients
Krüger K, Grust A, Muallah D, Patenge A, Wikman H, Mesa M, Knust E, Sartori A, Smeets R, Kluwe L, Friedrich R, Burg S
ANTICANCER RES. 2024;44(6):2369-2376.

Limited prognostic role of routine serum markers (AP, CEA, LDH and NSE) in oligorecurrent prostate cancer patients undergoing PSMA-radioguided surgery
Mehring G, Steinbach C, Pose R, Knipper S, Koehler D, Werner S, Riethdorf S, von Amsberg G, Ambrosini F, Maurer T
WORLD J UROL. 2024;42(1):.

Centrosomal Protein 55 Regulates Chromosomal Instability in Cancer Cells by Controlling Microtubule Dynamics
Muhs S, Paraschiakos T, Schäfer P, Joosse S, Windhorst S
CELLS-BASEL. 2024;13(16):.

KRAS and GNAS mutations in cell-free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms-an observational pilot study
Nitschke C, Tölle M, Walter P, Meißner K, Goetz M, Kropidlowski J, Berger A, Izbicki J, Nickel F, Hackert T, Pantel K, Wikman H, Uzunoglu F
MOL ONCOL. 2024 [Epub ahead of print].

Hypoxia-Induced Adaptations of N-Glycomes and Proteomes in Breast Cancer Cells and Their Secreted Extracellular Vesicles
Peng B, Bartkowiak K, Song F, Nissen P, Schlüter H, Siebels B
INT J MOL SCI. 2024;25(18):.

Isolation of Single Circulating Tumor Cells Using VyCAP Puncher System
Pereira-Veiga T, Behrens B, Broekmaat J, Oomens L, Stevens M, Tibbe A, Stoecklein N, Muinelo-Romay L, Piñeiro R, Costa C
2024. Single Cell Analysis. Gužvić M (Hrsg.). 1. Aufl. New York: Humana Press, 65-70.

EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma
Piper A, Penney C, Holliday J, Tincknell G, Ma Y, Napaki S, Pantel K, Brungs D, Ranson M
INT J MOL SCI. 2024;25(10):.

Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary
Pouyiourou M, Bochtler T, Coith C, Wikman H, Kraft B, Hielscher T, Stenzinger A, Riethdorf S, Pantel K, Krämer A
CLIN CHEM. 2024;70(1):297-306.

Multibiomarker panels in liquid biopsy for early detection of pancreatic cancer - a comprehensive review
Reese K, Pantel K, Smit D
J EXP CLIN CANC RES. 2024;43(1):.

Circulating extracellular vesicles as biomarker for diagnosis, prognosis and monitoring in glioblastoma patients
Ricklefs F, Wollmann K, Salviano-Silva A, Drexler R, Maire C, Kaul M, Reimer R, Schüller U, Heinemann S, Kolbe K, Mummert T, Glatzel M, Peine S, Gempt J, Westphal M, Dührsen L, Lamszus K
NEURO-ONCOLOGY. 2024;26(7):1280-1291.

Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells
Rieckmann L, Spohn M, Ruff L, Agorku D, Becker L, Borchers A, Krause J, O'Reilly R, Hille J, Velthaus-Rusik J, Beumer N, Günther A, Willnow L, Imbusch C, Iglauer P, Simon R, Franzenburg S, Winter H, Thomas M, Bokemeyer C, Gagliani N, Krebs C, Sprick M, Hardt O, Riethdorf S, Trumpp A, Stoecklein N, Peine S, Rosenstiel P, Pantel K, Loges S, Janning M
MOL CANCER. 2024;23(1):93.

Circulating Tumor Cells and Thromboembolic Events in Patients with Glioblastoma
Rolling C, Mohme M, Bokemeyer C, Westphal M, Riethdorf S, Lamszus K, Pantel K, Klingler F, Langer F
HAMOSTASEOLOGIE. 2024 [Epub ahead of print].

Diagnosing intravascular B-cell lymphoma using nanopore sequencing of cell-free DNA from cerebrospinal fluid
Schmidt B, Afflerbach A, Ludewig P, Dirksen P, Paulsen F, Magnus T, Alawi M, Schüller U, Weisel K, Bokemeyer C, Christopeit M
ESMO OPEN. 2024;9(11):103974.

HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
Schneegans S, Löptien J, Mojzisch A, Loreth D, Kretz O, Raschdorf C, Hanssen A, Gocke A, Siebels B, Gunasekaran K, Ding Y, Oliveira-Ferrer L, Brylka L, Schinke T, Schlüter H, Paatero I, Voß H, Werner S, Pantel K, Wikman H
J EXP CLIN CANC RES. 2024;43(1):110.

Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma
Sementsov M, Ott L, Kött J, Sartori A, Lusque A, Degenhardt S, Segier B, Heidrich I, Volkmer B, Greinert R, Mohr P, Simon R, Stadler J, Irwin D, Koch C, Andreas A, Deitert B, Thewes V, Trumpp A, Schneeweiss A, Belloum Y, Peine S, Wikman H, Riethdorf S, Schneider S, Gebhardt C, Pantel K, Keller L
EMBO MOL MED. 2024;16(7):1560-1578.

Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells
Smit D, Brauer H, Horn S, Yigit G, Haider M, Pogenberg V, Schumacher U, Pantel K, Jücker M
CELL SIGNAL. 2024;121:.

Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension-to-Adherent Transition
Smit D, Hoffer K, Bettin B, Kriegs M, Cayrefourcq L, Schumacher U, Pantel K, Alix-Panabières C, Jücker M
CANCER MED-US. 2024;13(20):e70339.

Circulating tumor cells as liquid biopsy markers in cancer patients
Smit D, Pantel K
MOL ASPECTS MED. 2024;96:101258.

Clinical applications of circulating tumor cells in patients with solid tumors
Smit D, Schneegans-Murano S, Pantel K
CLIN EXP METASTAS. 2024;41(4):403-411.

Central nervous system metastases in advanced non-small cell lung cancer: A review of the therapeutic landscape
Weller M, Remon J, Rieken S, Vollmuth P, Ahn M, Minniti G, Le Rhun E, Westphal M, Brastianos P, Soo R, Kirkpatrick J, Goldberg S, Öhrling K, Hegi-Johnson F, Hendriks L
CANCER TREAT REV. 2024;130:102807.

Plasma ctDNA as a treatment response biomarker in metastatic cancers: evaluation by the RECIST working group
Wyatt A, Litière S, Bidard F, Cabel L, Dyrskjøt L, Karlovich C, Pantel K, Petrie J, Philip R, Andrews H, Vellanki P, Tolmeijer S, Villalobos Alberu X, Alfano C, Bogaerts J, Calvo E, Chen A, Toledo R, de Vries E, Seymour L, Laurie S, Garralda E
CLIN CANCER RES. 2024;30(22):5034-5041.

Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients
Abdo M, Belloum Y, Heigener D, Welker L, von Weihe S, Schmidt M, Heuer-Olewinski N, Watermann I, Szewczyk M, Kropidlowski J, Pereira-Veiga T, Elmas H, Perner S, Steurer S, Wikman H, Pantel K, Reck M
MOL ONCOL. 2023;17(5):737-746.

Detection and Isolation of Circulating Tumor Cells from Breast Cancer Patients Using CUB Domain-Containing Protein 1
Bartkowiak K, Mossahebi Mohammadi P, Gärtner S, Kwiatkowski M, Andreas A, Geffken M, Peine S, Verpoort K, Scholz U, Deutsch T, Michel L, Schneeweiss A, Thewes V, Trumpp A, Müller V, Riethdorf S, Schlüter H, Pantel K
J PROTEOME RES. 2023;22(4):1213-1230.

Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann L, Freytag V, Ahlers A, Maar H, Gosau T, Baranowsky A, Schmitz R, Pantel K, Schumacher U, Haider M, Lange T
BONE. 2023;171:116741.

Baseline CTC Count as a Predictor of Long-Term Outcomes in High-Risk Prostate Cancer
Cieślikowski W, Milecki P, Świerczewska M, Ida A, Kasperczak M, Jankowiak A, Nowicki M, Pantel K, Alix-Panabières C, Zabel M, Antczak A, Budna-Tukan J
J PERS MED. 2023;13(4):.

PSMA-heterogeneity in metastatic castration-resistant prostate cancer: Circulating tumor cells, metastatic tumor burden, and response to targeted radioligand therapy
Derlin T, Riethdorf S, Schumacher U, Lafos M, Peine S, Coith C, Ross T, Pantel K, Bengel F
PROSTATE. 2023;83(11):1076-1088.

The Role of TAM Receptors in Bone
Engelmann J, Ragipoglu D, Ben Batalla I, Loges S
INT J MOL SCI. 2023;25(1):.

Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value
Franken A, Kraemer A, Sicking A, Watolla M, Rivandi M, Yang L, Warfsmann J, Polzer B, Friedl T, Meier-Stiegen F, Stoecklein N, Dayan D, Riethdorf S, Mueller V, Pantel K, Koch A, Hartkopf A, Krawczyk N, Ruckhaeberle E, Niederacher D, Fehm T, Neubauer H
BRIT J CANCER. 2023;128(9):1742-1752.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors
Heidrich I, Deitert B, Werner S, Pantel K
CANCER METAST REV. 2023;42(1):161-182.

Liquid Biopsy  – Ein neues diagnostisches Konzept in der Onkologie
Heidrich I, Roeper C, Rautmann C, Pantel K, Smit D
DEUT MED WOCHENSCHR. 2023;148(10):597-604.

Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy
Hohmann N, Sprick M, Pohl M, Ahmed A, Burhenne J, Kirchner M, Le Cornet L, Kratzmann M, Hajda J, Stenzinger A, Steindorf K, Delorme S, Schlemmer H, Riethdorf S, van Schaik R, Pantel K, Siveke J, Seufferlein T, Jäger D, Haefeli W, Trumpp A, Springfeld C
CTS-CLIN TRANSL SCI. 2023;16(12):2483-2493.

Label Efficient Classification in Liquid Biopsy Data by Self-supervision
Husseini H, Nielsen M, Pantel K, Wikman H, Riethdorf S, Werner R
2023. Bildverarbeitung für die Medizin 2023. Deserno T, Handels H, Maier A, Maier-Hein K, Palm C, Tolxdorff T (Hrsg.). 1. Aufl. Springer Vieweg, 261-266.

EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma
Kocheise L, Schoenlein M, Behrends B, Joerg V, Casar C, Fründt T, Renné T, Heumann A, Li J, Huber S, Lohse A, Pantel K, Riethdorf S, Wege H, Schulze K, von Felden J
SCI REP-UK. 2023;13(1):20827.

Circulating tumour cells for early detection of clinically relevant cancer
Lawrence R, Watters M, Davies C, Pantel K, Lu Y
NAT REV CLIN ONCOL. 2023;20(7):487-500.

Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients
Leest P, Janning M, Rifaela N, Azpurua M, Kropidlowski J, Loges S, Lozano N, Sartori A, Irwin D, Lamy P, Hiltermann T, Groen H, Pantel K, Kempen L, Wikman H, Schuuring E
INT J MOL SCI. 2023;24(17):.

Five plus three for the pancreas
Löhr J, Pantel K
CLIN CANCER RES. 2023;29(8):1387-1389.

Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Walter P, Badbaran A, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Bardenhagen J, Stern L, Tintelnot J, Schönlein M, Sinn M, van der Leest P, Simon R, Heumann A, Izbicki J, Pantel K, Wikman H, Uzunoglu F
CLIN CHEM. 2023;69(3):295-307.

Basal-like mammary carcinomas stimulate cancer stem cell properties through AXL-signaling to induce chemotherapy resistance
Pantelaiou-Prokaki G, Reinhardt O, Georges N, Agorku D, Hardt O, Prokakis E, Mieczkowska I, Deppert W, Wegwitz F, Alves F
INT J CANCER. 2023;152(9):1916-1932.

First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
Paschold L, Stein A, Thiele B, Tintelnot J, Henkes S, Coith C, Schultheiß C, Pantel K, Riethdorf S, Binder M
J IMMUNOTHER CANCER. 2023;11(6):.

RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, Dullin C, Rehling P, Glatzel M, Pantel K, Wikman H, Johnsen S, Gallwas J, Wegwitz F
CELL DEATH DIS. 2023;14(9):641.

The role of the desmosomal protein desmocollin 2 in tumour progression in triple negative breast cancer patients
Reimer F, Bryan S, Legler K, Karn T, Eppenberger-Castori S, Matschke J, Pereira-Veiga T, Wikman H, Witzel I, Müller V, Schmalfeldt B, Milde-Langosch K, Schumacher U, Stürken C, Oliveira-Ferrer L
CANCER CELL INT. 2023;23(1):47.

Zirkulierende Tumorzellen
Reimers N, Pantel K
2023. Kompendium Internistische Onkologie. Schmoll H (Hrsg.). 5. Aufl. Berlin, Heidelberg: Springer, 1-7.

„Liquid biopsy“ – schon reif für Therapieentscheidungen?
Roeper C, Hoehne I, Schlepper N, Koch C, Pantel K, Smit D
best practice onkologie. 2023;18(5):194 - 202.

MicroRNAs and their implications in CD4+ T-cells, oligodendrocytes and dendritic cells in multiple sclerosis pathogenesis
Safari A, Madadi S, Schwarzenbach H, Soleimani M, Safari A, Ahmadi M, Soleimani M
CURR MOL MED. 2023;23(7):630 - 647.

Experimental in vitro, ex vivo and in vivo models in prostate cancer research
Sailer V, von Amsberg G, Duensing S, Kirfel J, Lieb V, Metzger E, Offermann A, Pantel K, Schuele R, Taubert H, Wach S, Perner S, Werner S, Aigner A
NAT REV UROL. 2023;20(3):158-178.

Prognostic value of von Willebrand factor levels in patients with metastatic melanoma treated by immune checkpoint inhibitors
Stadler J, Keller L, Mess C, Bauer A, Koett J, Geidel G, Heidrich I, Vidal-Y-Sy S, Andreas A, Stramaglia C, Sementsov M, Haberstroh W, Deitert B, Hoehne I, Reschke R, Haalck T, Pantel K, Gebhardt C, Schneider S
J IMMUNOTHER CANCER. 2023;11(5):.

Preclinical models to study patient-derived circulating tumor cells and metastasis
Suvilesh K, Manjunath Y, Pantel K, Kaifi J
TRENDS CANCER. 2023;9(4):355-371.

A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer
Thomsen L, Honoré A, Reisæter L, Almås B, Børretzen A, Helle S, Førde K, Kristoffersen E, Kaada S, Melve G, Haslerud T, Biermann M, Bigalke I, Kvalheim G, Azeem W, Olsen J, Gabriel B, Knappskog S, Halvorsen O, Akslen L, Bahn D, Pantel K, Riethdorf S, Ragde H, Gjertsen B, Øyan A, Kalland K, Beisland C
CANCER IMMUNOL IMMUN. 2023;72(7):2357-2373.

Association Between Obesity and Circulating Tumor Cells in Early Breast Cancer Patients
Tzschaschel M, Friedl T, Schochter F, Schütze S, Polasik A, Fehm T, Pantel K, Schindlbeck C, Schneeweiss A, Schreier J, Tesch H, Lorenz R, Aivazova-Fuchs V, Häberle L, Fasching P, Janni W, Rack B, Fink V
CLIN BREAST CANCER. 2023;23(6):e345-e353.

ctHPV-DNA-basierte Präzisionsonkologie für Patienten mit Oropharynxkarzinom – wo stehen wir?
Wuerdemann N, Joosse S, Klasen C, Prinz J, Demers I, George J, Speel E, Wagner S, Klußmann J
LARYNGO RHINO OTOL. 2023;102(10):728-734.

Liquid Biopsy to Catch the Epigenetic Changes in Endometrial Cancer
Alix-Panabières C, Pantel K
CLIN CHEM. 2022;68(6):745-747.

Activated Eosinophils Predict Longer Progression-Free Survival under Immune Checkpoint Inhibition in Melanoma
Ammann N, Schwietzer Y, Mess C, Stadler J, Geidel G, Kött J, Pantel K, Schneider S, Utikal J, Bauer A, Gebhardt C
CANCERS. 2022;14(22):.

Circulating Cellular Communication Network Factor 1 Protein as a Sensitive Liquid Biopsy Marker for Early Detection of Breast Cancer
Bartkowiak K, Heidrich I, Kwiatkowski M, Banys-Paluchowski M, Andreas A, Wurlitzer M, Geffken M, Voß H, Zeller T, Blankenberg S, Peine S, Joosse S, Müller V, Schlüter H, Oliveira-Ferrer L, Pantel K
CLIN CHEM. 2022;68(2):344-353.

Interplay between coagulation and inflammation in cancer: Limitations and therapeutic opportunities
Bauer A, Gorzelanny C, Gebhardt C, Pantel K, Schneider S
CANCER TREAT REV. 2022;102:.

Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer
Besler K, Węglarz A, Keller L, von Amsberg G, Bednarz-Knoll N, Offermann A, Stoupiec S, Eltze E, Semjonow A, Boettcher L, Schneegans S, Perner S, Hauch S, Todenhöfer T, Peine S, Pantel K, Wikman H, Werner S
CLIN CHEM. 2022;68(7):973-983.

Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells
Brylka L, Jähn-Rickert K, Baranowsky A, Neven M, Horn M, Yorgan T, Wikman H, Werner S, Lübke A, Amling M, Busse B, Pantel K, Schinke T
CANCERS. 2022;14(3):.

With one eye on the future
Caldas C, Rescigno M, Turajlic S, Madabhushi A, Zhang Z, Lito P, Brown C, Pantel K, Haanen J, Duma N
CANCER CELL. 2022;40(3):221-225.

Possible tumour cell reimplantation during curative endoscopic therapy of superficial Barrett's carcinoma
Ehlken H, Schmitz R, Riethdorf S, Riethdorf L, Krause J, Karstens K, Schrader J, Viol F, Giannou A, Sterlacci W, Vieth M, Clauditz T, Kähler C, Mann O, Izbicki J, Huber S, Pantel K, Rösch T
GUT. 2022;71(2):277-286.

Regulation of bone homeostasis by MERTK and TYRO3
Engelmann J, Zarrer J, Gensch V, Riecken K, Berenbrok N, Luu T, Beitzen-Heineke A, Vargas-Delgado M, Pantel K, Bokemeyer C, Bhamidipati S, Darwish I, Masuda E, Burstyn-Cohen T, Alberto E, Ghosh S, Rothlin C, Hesse E, Taipaleenmäki H, Ben Batalla I, Loges S
NAT COMMUN. 2022;13(1):.

Kardioonkologie – was leistet die MRT? : Inflammation, Fibrose, Outcome
Erley J, Beitzen-Heineke A, Tahir E
RADIOLOGIE. 2022;62(11):941-946.

Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade
Eslami-S Z, Cortés-Hernández L, Thomas F, Pantel K, Alix-Panabières C
BRIT J CANCER. 2022;127(5):800-810.

Circulating tumor cells as a preoperative risk marker for occult metastases in patients with resectable cholangiocarcinoma
Fründt T, von Felden J, Krause J, Heumann A, Li J, Riethdorf S, Pantel K, Huber S, Lohse A, Wege H, Schulze K
FRONT ONCOL. 2022;12:.

Emerging precision diagnostics in advanced cutaneous squamous cell carcinoma
Geidel G, Heidrich I, Kött J, Schneider S, Pantel K, Gebhardt C
NPJ PRECIS ONCOL. 2022;6(1):.

Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation
Gerratana L, Pierga J, Reuben J, Davis A, Wehbe F, Dirix L, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Garcia-Saenz J, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, Bonotto M, Fernandez de Lascoiti A, De Mattos-Arruda L, Ignatiadis M, Sandri M, Generali D, De Angelis C, Dawson S, Janni W, Carañana V, Riethdorf S, Solomayer E, Puglisi F, Giuliano M, Pantel K, Bidard F, Cristofanilli M
ONCOLOGIST. 2022;27(7):e561-e570.

Tumor-Stroma Interaction in PDAC as a New Approach for Liquid Biopsy and its Potential Clinical Implications
Götze J, Nitschke C, Uzunoglu F, Pantel K, Sinn M, Wikman H
FRONT CELL DEV BIOL. 2022;10:.

Liquid biopsy: blood-based analyses of circulating cell-free DNA in xenografts
Heidrich I, Pantel K
EMBO MOL MED. 2022;14(8):.

Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions
Herbst J, Pantel K, Effenberger K, Wikman H
BRIT J CANCER. 2022;127(8):1403-1410.

Decellularized In Vitro Capillaries for Studies of Metastatic Tendency and Selection of Treatment
Huttala O, Loreth D, Staff S, Tanner M, Wikman H, Ylikomi T
BIOMEDICINES. 2022;10(2):.

Circulating DNA and Liquid Biopsies in the Management of Patients with Cancer
Joosse S, Pantel K
CANCER RES. 2022;82(12):2213-2215.

Detection of Hypomethylation in Long-ctDNA
Joosse S, Pantel K
CLIN CHEM. 2022;68(9):1115-1117.

NIPA (Nuclear Interaction Partner of ALK) Is Crucial for Effective NPM-ALK Mediated Lymphomagenesis
Kreutmair S, Lippert L, Klingeberg C, Albers-Leischner C, Yacob S, Shlyakhto V, Mueller T, Mueller-Rudorf A, Yu C, Gorantla S, Miething C, Duyster J, Illert A
FRONT ONCOL. 2022;12:.

Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo
Lange T, Valentiner U, Wicklein D, Maar H, Labitzky V, Ahlers A, Starzonek S, Genduso S, Staffeldt L, Pahlow C, Dück A, Stürken C, Baranowsky A, Bauer A, Bulk E, Schwab A, Riecken K, Börnchen C, Kiefmann R, Abraham V, DeLisser H, Gemoll T, Habermann J, Block A, Pantel K, Schumacher U
MOL THER. 2022;30(4):1536-1552.

Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
Leffers M, Herbst J, Kropidlowski J, Prieske K, Bohnen A, Peine S, Jaeger A, Prieske K, Goy Y, Schmalfeldt B, Pantel K, Wölber L, Effenberger K, Wikman H
CANCERS. 2022;14(16):.

Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels
Leong S, Naxerova K, Keller L, Pantel K, Witte M
CLIN EXP METASTAS. 2022;39(1):159-179.

Circulating Tumor-Macrophage Fusion Cells and Circulating Tumor Cells Complement Non-Small-Cell Lung Cancer Screening in Patients With Suspicious Lung-RADS 4 Nodules
Manjunath Y, Suvilesh K, Mitchem J, Avella Patino D, Kimchi E, Staveley-O'Carroll K, Pantel K, Yi H, Li G, Harris P, Chaudhuri A, Kaifi J
JCO PRECIS ONCOL. 2022;6:.

Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Merkens L, Sailer V, Lessel D, Janzen E, Greimeier S, Kirfel J, Perner S, Pantel K, Werner S, von Amsberg G
J EXP CLIN CANC RES. 2022;41(1):.

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Monteiro C, Miarka L, Perea-García M, Priego N, García-Gómez P, Álvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, Fustero-Torre C, Graña-Castro O, Troulé K, Caleiras E, Tezanos P, Muela P, Cintado E, Trejo J, Sepúlveda J, González-León P, Jiménez-Roldán L, Moreno L, Esteban O, Pérez-Núñez Á, Hernández-Lain A, Mazarico Gallego J, Ferrer I, Suárez R, Garrido-Martín E, Paz-Ares L, Dalmasso C, Cohen-Jonathan Moyal E, Siegfried A, Hegarty A, Keelan S, Varešlija D, Young L, Mohme M, Goy Y, Wikman H, Fernández-Alén J, Blasco G, Alcázar L, Cabañuz C, Grivennikov S, Ianus A, Shemesh N, Faria C, Lee R, Lorigan P, Le Rhun E, Weller M, Soffietti R, Bertero L, Ricardi U, Bosch-Barrera J, Sais E, Teixidor E, Hernández-Martínez A, Calvo A, Aristu J, Martin S, Gonzalez A, Adler O, Erez N, Valiente M
NAT MED. 2022;28(4):752-765.

Liquid Biopsy-basierte Überwachung der BRCA1-Promoter Hypermethylierung als Therapieresistenz Marker in Brust- und Eierstockkrebs
Netkova-Heintzen M, Wankner M, Joosse S
GYN Praktische Gynäkologie. 2022;27(6):494-500.

Detection and Characterization of Estrogen Receptor α Expression of Circulating Tumor Cells as a Prognostic Marker
Ningsi R, Elazezy M, Stegat L, Laakmann E, Peine S, Riethdorf S, Müller V, Pantel K, Joosse S
CANCERS. 2022;14(11):.

Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Konczalla L, Kropidlowski J, Pereira-Veiga T, Scognamiglio P, Schönrock M, Sinn M, Tölle M, Izbicki J, Pantel K, Uzunoglu F, Wikman H
BIOMEDICINES. 2022;10(11):.

Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
Nitschke C, Markmann B, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Schlüter H, Kwiatkowski M, Sinn M, Izbicki J, Pantel K, Güngör C, Uzunoglu F, Wikman H
CANCERS. 2022;14(18):.

Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2
Novoyatleva T, Rai N, Kojonazarov B, Veeroju S, Ben-Batalla I, Caruso P, Shihan M, Presser N, Götz E, Lepper C, Herpel S, Manaud G, Perros F, Gall H, Ghofrani H, Weissmann N, Grimminger F, Wharton J, Wilkins M, Upton P, Loges S, Morrell N, Seeger W, Schermuly R
COMMUN BIOL. 2022;5(1):.

Metastatic Breast Cancer Recurrence after Bone Fractures
Obi N, Werner S, Thelen F, Becher H, Pantel K
CANCERS. 2022;14(3):.

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation
Pantel K, Alix-Panabières C
J IMMUNOTHER CANCER. 2022;10(12):.

ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group
Pascual J, Attard G, Bidard F, Curigliano G, De Mattos-Arruda L, Diehn M, Italiano A, Lindberg J, Merker J, Montagut C, Normanno N, Pantel K, Pentheroudakis G, Popat S, Reis-Filho J, Tie J, Seoane J, Tarazona N, Yoshino T, Turner N
ANN ONCOL. 2022;33(8):750-768.

Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance
Pereira-Veiga T, Schneegans S, Pantel K, Wikman H
CELL REP. 2022;40(9):.

Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
Piffko A, Asey B, Dührsen L, Ristow I, Salamon J, Wikman H, Maire C, Lamszus K, Westphal M, Sauvigny T, Mohme M
FRONT ONCOL. 2022;12:.

Liquid Biopsy in Diagnosis and Prognosis of Non-Metastatic Prostate Cancer
Rzhevskiy A, Kapitannikova A, Butnaru D, Shpot E, Joosse S, Zvyagin A, Ebrahimi Warkiani M
BIOMEDICINES. 2022;10(12):.

Characterization of immunologically detectable T-cell sensitization, Immunohistochemical detection of pro-inflammatory cytokines, and clinical parameters of patients after allogeneic intraoral bone grafting procedures: a prospective randomized controlled clinical trial in humans
Solakoglu Ö, Götz W, von Baehr V, Heydecke G, Pantel K, Schwarzenbach H
BMC ORAL HEALTH. 2022;22(1):.

A 3-year prospective randomized clinical trial of alveolar bone crest response and clinical parameters through 1, 2, and 3 years of clinical function of implants placed 4 months after alveolar ridge preservation using two different allogeneic bone-grafting materials
Solakoğlu Ö, Ofluoğlu D, Schwarzenbach H, Heydecke G, Reißmann D, Ergun S, Götz W
INT J IMPLANT DENT. 2022;8(1):.

Characterization of circulating molecules and activities in plasma of patients after allogeneic and autologous intraoral bone grafting procedures: a prospective randomized controlled clinical trial in humans
Solakoglu Ö, Steinbach B, Götz W, Heydecke G, Schwarzenbach H
BMC ORAL HEALTH. 2022;22(1):.

Current and future clinical applications of ctDNA in immuno-oncology
Stadler J, Belloum Y, Deitert B, Sementsov M, Heidrich I, Gebhardt C, Keller L, Pantel K
CANCER RES. 2022;82(3):349-358.

Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses
Suvilesh K, Nussbaum Y, Radhakrishnan V, Manjunath Y, Avella D, Staveley-O'Carroll K, Kimchi E, Chaudhuri A, Shyu C, Li G, Pantel K, Warren W, Mitchem J, Kaifi J
MOL CANCER. 2022;21(1):.

Neoadjuvant Chemotherapy of Patients with Early Breast Cancer Is Associated with Increased Detection of Disseminated Tumor Cells in the Bone Marrow
Volmer L, Koch A, Matovina S, Dannehl D, Weiss M, Welker G, Hahn M, Engler T, Wallwiener M, Walter C, Oberlechner E, Brucker S, Pantel K, Hartkopf A
CANCERS. 2022;14(3):.

Immunotherapy in Advanced Prostate Cancer-Light at the End of the Tunnel?
von Amsberg G, Alsdorf W, Karagiannis P, Coym A, Kaune M, Werner S, Graefen M, Bokemeyer C, Merkens L, Dyshlovoy S
INT J MOL SCI. 2022;23(5):.

Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis
Wang Y, Liu X, Obser T, Bauer A, Heyes M, Starzonek S, Zulal M, Opitz K, Ott L, Riethdorf S, Lange T, Pantel K, Bendas G, Schneider S, Kusche-Gullberg M, Gorzelanny C
MATRIX BIOL. 2022;111:76-94.

Clinical management and biology of tumor dormancy in breast cancer
Werner S, Heidrich I, Pantel K
SEMIN CANCER BIOL. 2022;78:49-62.

Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
Westphal M, Pantel K, Ricklefs F, Maire C, Riethdorf S, Mohme M, Wikman H, Lamszus K
NEURO-ONCOL ADV. 2022;4(Suppl 2):ii45-ii52.

Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation
Woo H, Kim S, Kang H, Lee S, Lee S, Kim J, Gurel O, Kim S, Roh H, Lee J, Park Y, Shin H, Shin Y, Lee S, Oh S, Kim Y, Chae J, Lee S, Hong M, Cho B, Lee E, Pantel K, Kim H, Kim M
THERANOSTICS. 2022;12(8):3676-3689.

Evaluation of the Hamburg-Glasgow Classification in Pancreatic Cancer: Preoperative Staging by Combining Disseminated Tumor Load and Systemic Inflammation
Abdalla T, Almanfalouti V, Effenberger K, Uzunoglu F, Ghadban T, Dupreé A, Izbicki J, Pantel K, Reeh M
CANCERS. 2021;13(23):.

Prognostic value of preoperative circulating tumor cells counts in patients with UICC stage I-IV colorectal cancer
Abdalla T, Meiners J, Riethdorf S, König A, Melling N, Gorges T, Karstens K, Izbicki J, Pantel K, Reeh M
PLOS ONE. 2021;16(6):e0252897.

Blood-based detection of lung cancer using cysteine-rich angiogenic inducer 61 (CYR61) as a circulating protein biomarker: a pilot study
Ac Kar L, Casjens S, Andreas A, Raiko I, Brüning T, Geffken M, Peine S, Kollmeier J, Johnen G, Bartkowiak K, Weber D, Pantel K
MOL ONCOL. 2021;15(11):2877-2890.

Liquid Biopsy: From Discovery to Clinical Application
Alix-Panabières C, Pantel K
CANCER DISCOV. 2021;11(4):858-873.

Liquid biopsy: from discovery to clinical implementation
Alix-Panabières C, Pantel K
MOL ONCOL. 2021;15(6):1617-1621.

ViBiBa: Virtual BioBanking for the DETECT multicenter trial program - decentralized storage and processing
Asperger H, Cieslik J, Alberter B, Köstler C, Polzer B, Müller V, Pantel K, Riethdorf S, Koch A, Hartkopf A, Wiesmüller L, Janni W, Schochter F, Franken A, Niederacher D, Fehm T, Neubauer H
TRANSL ONCOL. 2021;14(8):101132.

Sensitive Blood-Based Detection of Asbestos-Associated Diseases Using Cysteine-Rich Angiogenic Inducer 61 as Circulating Protein Biomarker
Bartkowiak K, Casjens S, Andreas A, Ačkar L, Joosse S, Raiko I, Brüning T, Geffken M, Peine S, Johnen G, Weber D, Pantel K
CLIN CHEM. 2021;67(2):363-373.

Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells
Bartkowiak K, Heidrich I, Kwiatkowski M, Gorges T, Andreas A, Geffken M, Verpoort K, Müller V, Schlüter H, Pantel K
CANCERS. 2021;13(3):.

AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms
Beitzen-Heineke A, Berenbrok N, Waizenegger J, Päsler S, Gensch V, Udonta F, Vargas-Delgado M, Engelmann J, Hoffmann F, Schafhausen P, von Amsberg G, Riecken K, Beumer N, Imbusch C, Lorens J, Fischer T, Pantel K, Bokemeyer C, Ben Batalla I, Loges S
HEMASPHERE. 2021;5(9):.

DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients
Bold I, Specht A, Droste C, Zielinski A, Meyer F, Clauditz T, Münscher A, Werner S, Rothkamm K, Petersen C, Borgmann K
CANCERS. 2021;13(6):.

BRCA1 promoter hypermethylation on circulating tumor DNA correlates with improved survival of patients with ovarian cancer
Elazezy M, Prieske K, Kluwe L, Oliveira-Ferrer L, Peine S, Müller V, Woelber L, Schmalfeldt B, Pantel K, Joosse S
MOL ONCOL. 2021;15(12):3615-3625.

Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer
Elazezy M, Schwentesius S, Stegat L, Wikman H, Werner S, Mansour W, Failla A, Peine S, Müller V, Thiery J, Ebrahimi Warkiani M, Pantel K, Joosse S
CANCERS. 2021;13(15):.

Diagnostic and Prognostic Value of miR-16, miR-146a, miR-192 and miR-221 in Exosomes of Hepatocellular Carcinoma and Liver Cirrhosis Patients
Fründt T, Krause L, Hussey E, Steinbach B, Köhler D, von Felden J, Schulze K, Lohse A, Wege H, Schwarzenbach H
CANCERS. 2021;13(10):2484.

Disseminated tumour cells from the bone marrow of early breast cancer patients: Results from an international pooled analysis
Hartkopf A, Brucker S, Taran F, Harbeck N, von Au A, Naume B, Pierga J, Hoffmann O, Beckmann M, Rydén L, Fehm T, Aft R, Solà M, Walter V, Rack B, Schuetz F, Borgen E, Ta M, Bittner A, Fasching P, Fernö M, Krawczyk N, Weilbaecher K, Margelí M, Hahn M, Jueckstock J, Domschke C, Bidard F, Kasimir-Bauer S, Schoenfisch B, Kurt A, Wallwiener M, Gebauer G, Klein C, Wallwiener D, Janni W, Pantel K
EUR J CANCER. 2021;154:128-137.

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as a Liquid Biopsy Marker in Colorectal Cancer
Heidrich I, Abdalla T, Reeh M, Pantel K
CANCERS. 2021;13(18):.

Liquid biopsies: Potential and challenges
Heidrich I, Ačkar L, Mossahebi Mohammadi P, Pantel K
INT J CANCER. 2021;148(3):528-545.

Novel approaches to target the microenvironment of bone metastasis
Hofbauer L, Bozec A, Rauner M, Jakob F, Perner S, Pantel K
NAT REV CLIN ONCOL. 2021;18(8):488-505.

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
Jacobsen H, Walendy-Gnirß K, Tekin-Bubenheim N, Kouassi N, Ben-Batalla I, Berenbrok N, Wolff M, Dos Reis V, Zickler M, Scholl L, Gries A, Jania H, Kloetgen A, Düsedau A, Pilnitz-Stolze G, Jeridi A, Yildirim A, Fuchs H, Gailus-Durner V, Stoeger C, de Angelis M, Manuylova T, Klingel K, Culley F, Behrends J, Loges S, Schneider B, Krauss-Etschmann S, Openshaw P, Gabriel G
NAT COMMUN. 2021;12(1):4957.

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Keller L, Belloum Y, Wikman H, Pantel K
BRIT J CANCER. 2021;124(2):345-358.

Possible Role of Circulating Tumour Cells for Prediction of Salvage Lymph Node Dissection Outcome in Patients with Early Prostate Cancer Recurrence
Knipper S, Riethdorf S, Werner S, Tilki D, Graefen M, Pantel K, Maurer T
EUR UROL OPEN SCI. 2021;34:55-58.

2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: identification of a new and potent inhibitor
Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski S, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter B, Diercks B, Guse A
BBA-MOL CELL RES. 2021;1868(6):118988.

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse S, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider S, Belczacka I, Volkmer B, Greinert R, Yaspo M, Harter P, Pantel K, Wikman H
INT J MOL SCI. 2021;22(13):.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Enumeration and Changes in Circulating Tumor Cells and Their Prognostic Value in Patients Undergoing Cytoreductive Radical Prostatectomy for Oligometastatic Prostate Cancer-Translational Research Results from the Prospective ProMPT trial
Mandel P, Huland H, Tiebel A, Haese A, Salomon G, Budäus L, Tilki D, Chun F, Heinzer H, Graefen M, Pantel K, Riethdorf S, Steuber T
EUR UROL FOCUS. 2021;7(1):55-62.

Infiltration of Immune Competent Cells into Primary Tumors and Their Surrounding Connective Tissues in Xenograft and Syngeneic Mouse Models
Metzen M, Bruns M, Deppert W, Schumacher U
INT J MOL SCI. 2021;22(8):4213.

P02.01 A strategy to personalize the use of radiation in patients with brain metastasis based on S100A9-mediated resistance
Miarka L, Monteiro C, Dalmasso C, Yebra N, Fustero-Torre C, Hegarty A, Keelan S, Goy Y, Mohme M, Caleiras E, Vareslija D, Young L, Soffietti R, Fernández-Alén J, Blasco G, Alcázar L, Sepúlveda J, Pérez A, Lain A, Siegfried A, Wikman H, Cohen-Jonathan Moyal E, Valiente M
NEURO-ONCOLOGY. 2021;23(Supplement_2):ii17-ii17.

Decreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments
Mieczkowska I, Pantelaiou-Prokaki G, Prokakis E, Schmidt G, Müller-Kirschbaum L, Werner M, Sen M, Velychko T, Jannasch K, Dullin C, Napp J, Pantel K, Wikman H, Wiese M, Kramm C, Alves F, Wegwitz F
CELL DEATH DIS. 2021;12(12):.

Prognostic relevance of the HER2 status of circulating tumor cells in metastatic breast cancer patients screened for participation in the DETECT study program
Müller V, Banys-Paluchowski M, Friedl T, Fasching P, Schneeweiss A, Hartkopf A, Wallwiener D, Rack B, Meier-Stiegen F, Huober J, Rübner M, Hoffmann O, Müller L, Janni W, Wimberger P, Jäger B, Pantel K, Riethdorf S, Harbeck N, Fehm T
ESMO OPEN. 2021;6(6):.

Detection of Circulating Tumor Cells (CTCs) in Patients with Testicular Germ Cell Tumors
Nastały P, Honecker F, Pantel K, Riethdorf S
Methods Mol Biol. 2021;2195:245-261.

Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID
Neves R, Ammerlaan W, Andree K, Bender S, Cayrefourcq L, Driemel C, Koch C, Luetke-Eversloh M, Oulhen M, Rossi E, Alix-Panabières C, Betsou F, Farace F, Riethdorf S, Schlange T, Wikman H, Zamarchi R, Pantel K, Terstappen L, Stoecklein N
CLIN CHEM. 2021;67(4):631-641.

The Long-Term Prognostic Significance of Circulating Tumor Cells in Ovarian Cancer-A Study of the OVCAD Consortium
Obermayr E, Reiner A, Brandt B, Braicu E, Reinthaller A, Loverix L, Concin N, Woelber L, Mahner S, Sehouli J, Vergote I, Zeillinger R
CANCERS. 2021;13(11):.

Analysis of tripartite motif (TRIM) family gene expression in prostate cancer bone metastases
Offermann A, Kang D, Watermann C, Weingart A, Hupe M, Saraji A, Stegmann-Frehse J, Kruper R, Schüle R, Pantel K, Taubert H, Duensing S, Culig Z, Aigner A, Klapper W, Jonigk D, Philipp Kühnel M, Merseburger A, Kirfel J, Sailer V, Perner S
CARCINOGENESIS. 2021;42(12):1475-1484.

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions
Pantano F, Croset M, Driouch K, Bednarz-Knoll N, Iuliani M, Ribelli G, Bonnelye E, Wikman H, Geraci S, Bonin F, Simonetti S, Vincenzi B, Hong S, Sousa S, Pantel K, Tonini G, Santini D, Clézardin P
ONCOGENE. 2021;40(7):1284-1299.

Liquid Biopsy: Blood-Based Analyses of ctDNA and CTCs
Pantel K
CLIN CHEM. 2021;67(11):1437-1439.

Longitudinal CTCs gene expression analysis on metastatic castration-resistant prostate cancer patients treated with docetaxel reveals new potential prognosis markers
Pereira-Veiga T, González-Conde M, León-Mateos L, Piñeiro-Cid R, Abuín C, Muinelo-Romay L, Martínez-Fernández M, Brea Iglesias J, García González J, Anido U, Aguín-Losada S, Cebey V, Costa C, López-López R
CLIN EXP METASTAS. 2021;38(2):239-251.

Transcriptome Analysis in Vulvar Squamous Cell Cancer
Prieske K, Alawi M, Jaeger A, Wankner M, Eylmann K, Reuter S, Lebok P, Burandt E, Blessin N, Schmalfeldt B, Prieske K, Joosse S, Woelber L
CANCERS. 2021;13(24):.

High Serum Levels of Wnt Signaling Antagonist Dickkopf-Related Protein 1 Are Associated with Impaired Overall Survival and Recurrence in Esophageal Cancer Patients
Ramirez J, Smit D, Viol F, Schrader J, Ghadban T, Pantel K, Izbicki J, Reeh M
CANCERS. 2021;13(19):.

Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain
Robador J, Feinauer M, Schneider S, Mayer F, Gorzelanny C, Sacharow A, Liu X, Berghoff A, Brehm M, Hirsch D, Stadler J, Vidal-Y-Si S, Wladykowski E, Asong M, Nowak K, Seiz-Rosenhagen M, Umansky V, Mess C, Pantel K, Winkler F, Bauer A
NEURO-ONCOL ADV. 2021;3(1):.

Functional Characterization of Circulating Tumor Cells (CTCs) from Metastatic ER+/HER2- Breast Cancer Reveals Dependence on HER2 and FOXM1 for Endocrine Therapy Resistance and Tumor Cell Survival: Implications for Treatment of ER+/HER2- Breast Cancer
Roßwag S, Cotarelo C, Pantel K, Riethdorf S, Sleeman J, Schmidt M, Thaler S
CANCERS. 2021;13(8):.

Exosomes in Immune Regulation
Schwarzenbach H, Gahan P
NON-CODING RNA. 2021;7(1):.

Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy
Smit D, Pantel K, Jücker M
BIOCHEM PHARMACOL. 2021;188:114589.

Diagnostik und Therapie von Tumoren mit NTRK-Genfusionen
Stenzinger A, van Tilburg C, Tabatabai G, Länger F, Graf N, Griesinger F, Heukamp L, Hummel M, Klingebiel T, Hettmer S, Vokuhl C, Merkelbach-Bruse S, Overkamp F, Reichardt P, Scheer M, Weichert W, Westphalen C, Bokemeyer C, Ivanyi P, Loges S, Schirmacher P, Wörmann B, Bielack S, Seufferlein T
PATHOLOGE. 2021;42(1):103-115.

A Comprehensive Molecular Analysis of in Vivo Isolated EpCAM-Positive Circulating Tumor Cells in Breast Cancer
Strati A, Zavridou M, Kallergi G, Politaki E, Kuske A, Gorges T, Riethdorf S, Joosse S, Koch C, Bohnen A, Mueller V, Koutsodontis G, Kontopodis E, Poulakaki N, Psyrri A, Mavroudis D, Georgoulias V, Pantel K, Lianidou E
CLIN CHEM. 2021;67(10):1395-1405.

The regulatory effect of hyaluronan on human mesenchymal stem cells' fate modulates their interaction with cancer cells in vitro
Vogeley C, Degistirici Ö, Twarock S, Wladarz J, Reiners O, Gorges T, Fischer J, Meisel R, Gorges K
SCI REP-UK. 2021;11(1):.

Circulating DNA and other biomarker for early diagnosis: Great potential, but challenges recognized
Babayan A, Reimers N, Pantel K
2020. World Cancer Report. Wild C, Weiderpass E, Stewart B (Hrsg.). 1. Aufl. Lyon: World Health Organization, 550 -556.

In Vitro Modeling of Reoxygenation Effects on mRNA and Protein Levels in Hypoxic Tumor Cells upon Entry into the Bloodstream
Bartkowiak K, Koch C, Gärtner S, Andreas A, Gorges T, Pantel K
CELLS-BASEL. 2020;9(5):.

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
Belloum Y, Janning M, Mohme M, Simon R, Kropidlowski J, Sartori A, Irwin D, Westphal M, Lamszus K, Loges S, Riethdorf S, Pantel K, Wikman H
CELLS-BASEL. 2020;9(11):.

Evaluation of PD-L1 expression on circulating tumor cells (CTCs) in patients with advanced urothelial carcinoma (UC)
Bergmann S, Coym A, Ott L, Soave A, Rink M, Janning M, Stoupiec M, Coith C, Peine S, von Amsberg G, Pantel K, Riethdorf S
ONCOIMMUNOLOGY. 2020;9(1):.

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms
Czech-Sioli M, Günther T, Therre M, Spohn M, Indenbirken D, Theiss J, Riethdorf S, Qi M, Alawi M, Wülbeck C, Fernandez-Cuesta I, Esmek F, Becker J, Grundhoff A, Fischer N
PLOS PATHOG. 2020;16(8):.

HER2-targeted therapy influences CTC status in metastatic breast cancer
Deutsch T, Riethdorf S, Fremd C, Feisst M, Nees J, Fischer C, Hartkopf A, Pantel K, Trumpp A, Schütz F, Schneeweiss A, Wallwiener M
BREAST CANCER RES TR. 2020;182(1):127-136.

Simultaneous Magnetic Particle Imaging and Navigation of large superparamagnetic nanoparticles in bifurcation flow experiments
Griese F, Knopp T, Grüttner C, Thieben F, Müller K, Loges S, Ludewig P, Gdaniec N
J MAGN MAGN MATER. 2020;2020(498):.

Rationale and Design of the Hamburg City Health Study
Jagodzinski A, Johansen C, Koch-Gromus U, Aarabi G, Adam G, Anders S, Augustin M, der Kellen R, Beikler T, Behrendt C, Betz C, Bokemeyer C, Borof K, Briken P, Busch C, Büchel C, Brassen S, Debus E, Eggers L, Fiehler J, Gallinat J, Gellißen S, Gerloff C, Girdauskas E, Gosau M, Graefen M, Härter M, Harth V, Heidemann C, Heydecke G, Huber T, Hussein Y, Kampf M, von dem Knesebeck O, Konnopka A, König H, Kromer R, Kubisch C, Kühn S, Loges S, Löwe B, Lund G, Meyer C, Nagel L, Nienhaus A, Pantel K, Petersen E, Püschel K, Reichenspurner H, Sauter G, Scherer M, Scherschel K, Schiffner U, Schnabel R, Schulz H, Smeets R, Sokalskis V, Spitzer M, Terschüren C, Thederan I, Thoma T, Thomalla G, Waschki B, Wegscheider K, Wenzel J, Wiese S, Zyriax B, Zeller T, Blankenberg S
EUR J EPIDEMIOL. 2020;35(2):169-181.

Tumor-Associated Release of Prostatic Cells into the Blood after Transrectal Ultrasound-Guided Biopsy in Patients with Histologically Confirmed Prostate Cancer
Joosse S, Beyer B, Gasch C, Nastały P, Kuske A, Isbarn H, Horst L, Hille C, Gorges T, Cayrefourcq L, Alix-Panabières C, Tennstedt P, Riethdorf S, Schlomm T, Pantel K
CLIN CHEM. 2020;66(1):161-168.

BRCA1 promoter methylation and clinical outcomes in ovarian cancer: an individual patient data meta-analysis
Kalachand R, Stordal B, Madden S, Chandler B, Cunningham J, Goode E, Ruscito I, Braicu E, Sehouli J, Ignatov A, Yu H, Katsaros D, Mills G, Lu K, Carey M, Timms K, Kupryjanczyk J, Rzepecka I, Podgorska A, McAlpine J, Swisher E, Bernards S, O'Riain C, O'Toole S, O'Leary J, Bowtell D, Thomas D, Prieske K, Joosse S, Woelber L, Chaudhry P, Häfner N, Runnebaum I, Hennessy B
JNCI-J NATL CANCER I. 2020;112(12):1190-1203.

Lymph Node and Bone Marrow Micrometastases Define the Prognosis of Patients with pN0 Esophageal Cancer
Karstens K, Ghadban T, Effenberger K, Sauter G, Pantel K, Izbicki J, Vashist Y, König A, Reeh M
CANCERS. 2020;12(3):588.

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity
Koch C, Kuske A, Joosse S, Yigit G, Sflomos G, Thaler S, Smit D, Werner S, Borgmann K, Gärtner S, Mossahebi Mohammadi P, Battista L, Cayrefourcq L, Altmüller J, Salinas-Riester G, Raithatha K, Zibat A, Goy Y, Ott L, Bartkowiak K, Tan T, Zhou Q, Speicher M, Müller V, Gorges T, Jücker M, Thiery J, Brisken C, Riethdorf S, Alix-Panabières C, Pantel K
EMBO MOL MED. 2020;12(9):.

Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
Lampignano R, Neumann M, Weber S, Kloten V, Herdean A, Voss T, Groelz D, Babayan A, Tibbesma M, Schlumpberger M, Chemi F, Rothwell D, Wikman H, Galizzi J, Bergheim I, Russnes H, Mussolin B, Bonin S, Voigt C, Musa H, Pinzani P, Lianidou E, Brady G, Speicher M, Pantel K, Betsou F, Schuuring E, Kubista M, Ammerlaan W, Sprenger-Haussels M, Schlange T, Heitzer E
CLIN CHEM. 2020;66(1):149-160.

Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer
Lange T, Samatov T, Galatenko V, Steffen P, von Kriegstein H, Spethmann T, Wicklein D, Maar H, Kupfernagel K, Labitzky V, Hanika S, Starzonek S, Ahlers A, Riecken K, Simon R, Polonski A, Sauter G, Schlomm T, Huland H, Johnsen S, Schlüter H, Tonevitsky A, Schumacher U
EUR J CANCER. 2020;137:93-107.

Author Correction: Intraoperative detection of circulating tumor cells in pulmonary venous blood during metastasectomy for colorectal lung metastases
Le U, Bronsert P, Picardo F, Riethdorf S, Haager B, Rylski B, Czerny M, Beyersdorf F, Wiesemann S, Pantel K, Passlick B, Kaifi J, Schmid S
SCI REP-UK. 2020;10(1):7633.

Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform
Liu H, Koch C, Haller A, Joosse S, Kumar R, Vellekoop M, Horst L, Keller L, Babayan A, Failla A, Jensen J, Peine S, Keplinger F, Fuchs H, Pantel K, Hirtz M
ADV BIOSYST. 2020;4(2):e1900162.

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer
Meyer F, Becker S, Classen S, Parplys A, Mansour W, Riepen B, Timm S, Ruebe C, Jasin M, Wikman H, Petersen C, Rothkamm K, Borgmann K
CELLS-BASEL. 2020;9(1):.

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Mohme M, Maire C, Schliffke S, Joosse S, Alawi M, Matschke J, Schüller U, Dierlamm J, Martens T, Pantel K, Riethdorf S, Lamszus K, Westphal M
ACTA NEUROPATHOL COM. 2020;8(1):.

ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg J, Loreth D, Brylka L, Werner S, Karbanova J, Gandrass M, Schneegans S, Besler K, Hamester F, Robador J, Bauer A, Werner Schneider S, Wrage M, Lamszus K, Matschke J, Vashist Y, Uzunoglu G, Steurer S, Horst A, Oliveira-Ferrer L, Glatzel M, Schinke T, Corbeil D, Pantel K, Maire C, Wikman H
NEURO-ONCOLOGY. 2020;22(7):955-966.

Genomic characterization of vulvar squamous cell carcinoma
Prieske K, Alawi M, Oliveira-Ferrer L, Jaeger A, Eylmann K, Burandt E, Schmalfeldt B, Joosse S, Woelber L
GYNECOL ONCOL. 2020;158(3):547-554.

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner
Rieckhoff J, Meyer F, Classen S, Zielinski A, Riepen B, Wikman H, Petersen C, Rothkamm K, Borgmann K, Parplys A
CANCERS. 2020;12(10):.

The Impact of Circulating Tumor Cells on Venous Thromboembolism and Cardiovascular Events in Bladder Cancer Patients Treated with Radical Cystectomy
Rink M, Riethdorf S, Yu H, Kölker M, Vetterlein M, Dahlem R, Fisch M, Pantel K, Soave A
J CLIN MED. 2020;9(11):.

Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients
Schneegans S, Lück L, Besler K, Bluhm L, Stadler J, Staub J, Greinert R, Volkmer B, Kubista M, Gebhardt C, Sartori A, Irwin D, Serkkola E, Af Hällström T, Lianidou E, Sprenger-Haussels M, Hussong M, Mohr P, Schneider S, Shaffer J, Pantel K, Wikman H
MOL ONCOL. 2020;14(5):1001-1015.

Predictive value of exosomes and their cargo in drug response/resistance of breast cancer patients
Schwarzenbach H, Gahan P
CANCER DRUG RESIST. 2020;3(1):63-82.

High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors
Smit D, Cayrefourcq L, Haider M, Hinz N, Pantel K, Alix-Panabières C, Jücker M
CELLS-BASEL. 2020;9(9):.

Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy
Soave A, Kluwe L, Yu H, Rink M, Gild P, Vetterlein M, Marks P, Sauter G, Fisch M, Meyer C, Ludwig T, Dahlem R, Minner S, Pantel K, Steinbach B, Schwarzenbach H
SCI REP-UK. 2020;10(1):21562.

The Lack of Evidence for an Association between Cancer Biomarker Conversion Patterns and CTC-Status in Patients with Metastatic Breast Cancer
Stefanovic S, Deutsch T, Riethdorf S, Fischer C, Hartkopf A, Sinn P, Feisst M, Pantel K, Golatta M, Brucker S, Sütterlin M, Schneeweiss A, Wallwiener M
INT J MOL SCI. 2020;21(6):.

Correction: Role of growth arrest-specific gene 6-mer axis in multiple myeloma
Waizenegger J, Ben-Batalla I, Weinhold N, Meissner T, Wroblewski M, Janning M, Riecken K, Binder M, Atanackovic D, Taipaleenmaeki H, Schewe D, Sawall S, Gensch V, Cubas-Cordova M, Seckinger A, Atanackovic D, Hesse E, Kröger N, Fehse B, Hose D, Klein B, Raab M, Pantel K, Bokemeyer C, Loges S
LEUKEMIA. 2020;34(9):2542.

Clinical Relevance of Circulating Tumor Cells in Esophageal Cancer Detected by a Combined MACS Enrichment Method
Woestemeier A, Harms-Effenberger K, Karstens K, Konczalla L, Ghadban T, Uzunoglu F, Izbicki J, Bockhorn M, Pantel K, Reeh M
CANCERS. 2020;12(3):718.

The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
Xie W, Miehe M, Laufer S, Johnsen S
CELL DEATH DIS. 2020;11(4):287.

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Aktas B, Fasching P, Hartkopf A, Janni W, Kasimir-Bauer S, Pantel K, Schön G, Rack B, Riethdorf S, Solomayer E, Fehm T, Müller V
SCI REP-UK. 2019;9(1):2318.

Sexual dimorphism in solid and hematological malignancies
Ben-Batalla I, Vargas-Delgado M, Meier L, Loges S
SEMIN IMMUNOPATHOL. 2019;41(2):251-263.

Analysis of Circulating Tumor Cells in Patients with Non-Metastatic High-Risk Prostate Cancer before and after Radiotherapy Using Three Different Enumeration Assays
Budna-Tukan J, Świerczewska M, Mazel M, Cieślikowski W, Ida A, Jankowiak A, Antczak A, Nowicki M, Pantel K, Azria D, Zabel M, Alix-Panabières C
CANCERS. 2019;11(6):.

In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy
Chen S, Tauber G, Langsenlehner T, Schmölzer L, Pötscher M, Riethdorf S, Kuske A, Leitinger G, Kashofer K, Czyż Z, Polzer B, Pantel K, Sedlmayr P, Kroneis T, El-Heliebi A
CANCERS. 2019;11(7):.

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
Cristofanilli M, Pierga J, Reuben J, Rademaker A, Davis A, Peeters D, Fehm T, Nolé F, Gisbert-Criado R, Mavroudis D, Grisanti S, Giuliano M, Garcia-Saenz J, Stebbing J, Caldas C, Gazzaniga P, Manso L, Zamarchi R, de Lascoiti A, De Mattos-Arruda L, Ignatiadis M, Cabel L, van Laere S, Meier-Stiegen F, Sandri M, Vidal-Martinez J, Politaki E, Consoli F, Generali D, Cappelletti M, Diaz-Rubio E, Krell J, Dawson S, Raimondi C, Rutten A, Janni W, Munzone E, Carañana V, Agelaki S, Almici C, Dirix L, Solomayer E, Zorzino L, Darrigues L, Reis-Filho J, Gerratana L, Michiels S, Bidard F, Pantel K
CRIT REV ONCOL HEMAT. 2019;134:39-45.

Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients
Gorges K, Wiltfang L, Gorges T, Sartori A, Hildebrandt L, Keller L, Volkmer B, Peine S, Babayan A, Moll I, Schneider S, Twarock S, Mohr P, Fischer J, Pantel K
CANCERS. 2019;11(11):1685.

Detection of Androgen Receptor Variant 7 (ARV7) mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer
Hille C, Gorges T, Riethdorf S, Mazel M, Steuber T, Amsberg G, König F, Peine S, Alix-Panabières C, Pantel K
CELLS-BASEL. 2019;8(9):.

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
Janning M, Kobus F, Babayan A, Wikman H, Velthaus J, Bergmann S, Schatz S, Falk M, Berger L, Böttcher L, Päsler S, Gorges T, O'Flaherty L, Hille C, Joosse S, Simon R, Tiemann M, Bokemeyer C, Reck M, Riethdorf S, Pantel K, Loges S
CANCERS. 2019;11(6):.

Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer
Jauch S, Riethdorf S, Sprick M, Schütz F, Schönfisch B, Brucker S, Deutsch T, Nees J, Saini M, Becker L, Burwinkel B, Sinn P, Marmé F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A
BREAST CANCER RES TR. 2019;173(1):155-165.

Biology and clinical relevance of EpCAM
Keller L, Werner S, Pantel K
CELL STRESS. 2019;3(6):165-180.

Prospective Comparison of the Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of a Single Patient's Cohort With Esophageal Cancer
Konczalla L, Ghadban T, Effenberger K, Wöstemeier A, Riethdorf S, Uzunoglu F, Izbicki J, Pantel K, Bockhorn M, Reeh M
ANN SURG. 2019;273(2):299-305.

Liquid Biopsies
Lianidou E, Pantel K
GENE CHROMOSOME CANC. 2019;58(4):219-232.

EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer
Lindsay C, Blackhall F, Carmel A, Fernandez-Gutierrez F, Gazzaniga P, Groen H, Hiltermann T, Krebs M, Loges S, López-López R, Muinelo-Romay L, Pantel K, Priest L, Riethdorf S, Rossi E, Terstappen L, Wikman H, Soria J, Farace F, Renehan A, Dive C, Besse B, Michiels S
EUR J CANCER. 2019;117:60-68.

ALDH1-positive intratumoral stromal cells indicate differentiated epithelial-like phenotype and good prognosis in prostate cancer
Nastały P, Filipska M, Morrissey C, Eltze E, Semjonow A, Brandt B, Pantel K, Bednarz-Knoll N
TRANSL RES. 2019;203:49-56.

Somatic aberrations of BRCA1 gene are associated with ALDH1, EGFR, and tumor progression in prostate cancer
Omari A, Nastały P, Stoupiec S, Bałabas A, Dąbrowska M, Bielińska B, Huss S, Pantel K, Semjonow A, Eltze E, Brandt B, Bednarz-Knoll N
INT J CANCER. 2019;144(3):607-614.

Recent advances in Circulating Nucleic Acids in oncology
Otandault A, Anker P, Al Amir Dache Z, Guillaumon V, Meddeb R, Pastor B, Pisareva E, Sanchez C, Tanos R, Tousch G, Schwarzenbach H, Thierry A
ANN ONCOL. 2019;30(3):374-384.

Liquid biopsy and minimal residual disease - latest advances and implications for cure
Pantel K, Alix-Panabières C
NAT REV CLIN ONCOL. 2019;16(7):409-424.

Circulating Tumor Cells in Prostate Cancer: From Discovery to Clinical Utility
Pantel K, Hille C, Scher H
CLIN CHEM. 2019;65(1):87-99.

Möglichkeiten und Grenzen von Liquid Biopsy
Pantel K, Reimers N
Osteoporose, Orthopädie &Rheuma aktuell. 2019;2019(4):.

Liquid biopsy: novel technologies and clinical applications
Reimers N, Pantel K
CLIN CHEM LAB MED. 2019;57(3):312-316.

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs F, Maire C, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland D, Flitsch J, Martens T, Schmidt N, Peine S, Breakefield X, Lawler S, Chiocca E, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K
J EXTRACELL VESICLES. 2019;8(1):1588555.

Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H
BREAST CANCER RES. 2019;21(1):101.

Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma
Riethdorf S, Hildebrandt L, Heinzerling L, Heitzer E, Fischer N, Bergmann S, Mauermann O, Waldispühl-Geigl J, Coith C, Schön G, Peine S, Schuler G, Speicher M, Moll I, Pantel K
CLIN CHEM. 2019;65(3):462-472.

The current role and future directions of circulating tumor cells and circulating tumor DNA in urothelial carcinoma of the bladder
Rink M, Schwarzenbach H, Riethdorf S, Soave A
WORLD J UROL. 2019;37(9):1785-1799.

The current role of circulating biomarkers in non-muscle invasive bladder cancer
Rink M, Schwarzenbach H, Vetterlein M, Riethdorf S, Soave A
TRANSL ANDROL UROL. 2019;8(1):61-75.

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.

Copy Number Variation Analysis on Cell-Free Serum DNA
Schwarzenbach H
2019. Cell-free DNA as Diagnostic Markers. Casadio V, Salvi S (Hrsg.). 1. Aufl. New York: Humana Press, 85-93.

Presence of Circulating Tumor Cells in High-Risk Early Breast Cancer During Follow-Up and Prognosis
Trapp E, Janni W, Schindlbeck C, Jückstock J, Andergassen U, de Gregorio A, Alunni-Fabbroni M, Tzschaschel M, Polasik A, Koch J, Friedl T, Fasching P, Haeberle L, Fehm T, Schneeweiss A, Beckmann M, Pantel K, Mueller V, Rack B, Scholz C
JNCI-J NATL CANCER I. 2019;111(4):380-387.

11th International Symposium on Minimal Residual Cancer (ISMRC): 3-5 May 2018, Montpellier, France
Alix-Panabières C, Pantel K
CLIN EXP METASTAS. 2018;35(3):87-90.

Abstracts from the 11th International Symposium on Minimal Residual Disease, 3-5 May 2018, Montpellier, France
Alix-Panabières C, Pantel K
CLIN EXP METASTAS. 2018;35(3):167-217.

Clinical utility of circulating non-coding RNAs - an update
Anfossi S, Babayan A, Pantel K, Calin G
NAT REV CLIN ONCOL. 2018;15(9):541-563.

Advances in liquid biopsy approaches for early detection and monitoring of cancer
Babayan A, Pantel K
GENOME MED. 2018;10(1):21.

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany
Bailey D, Pichler B, Gückel B, Antoch G, Barthel H, Bhujwalla Z, Biskup S, Biswal S, Bitzer M, Boellaard R, Braren R, Brendle C, Brindle K, Chiti A, la Fougère C, Gillies R, Goh V, Goyen M, Hacker M, Heukamp L, Knudsen G, Krackhardt A, Law I, Morris J, Nikolaou K, Nuyts J, Ordonez A, Pantel K, Quick H, Riklund K, Sabri O, Sattler B, Troost E, Zaiss M, Zender L, Beyer T
MOL IMAGING BIOL. 2018;20(1):4-20.

Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer
Banys-Paluchowski M, Fehm T, Janni W, Aktas B, Fasching P, Kasimir-Bauer S, Milde-Langosch K, Pantel K, Rack B, Riethdorf S, Solomayer E, Witzel I, Müller V
BMC CANCER. 2018;18(1):541.

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
Banys-Paluchowski M, Fehm T, Witzel I, Aktas B, Fasching P, Hartkopf A, Janni W, Kasimir-Bauer S, Pantel K, Schön G, Rack B, Riethdorf S, Solomayer E, Müller V
GEBURTSH FRAUENHEILK. 2018;78(11):1151.

The clinical relevance of serum vascular endothelial growth factor (VEGF) in correlation to circulating tumor cells and other serum biomarkers in patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Riethdorf S, Pantel K, Rack B, Janni W, Fasching P, Aktas B, Kasimir-Bauer S, Hartkopf A, Solomayer E, Fehm T, Müller V
BREAST CANCER RES TR. 2018;172(1):93-104.

Prevalence of circulating tumor cells in early breast cancer patients 2 and 5 years after adjuvant treatment
Bauer E, Schochter F, Widschwendter P, DeGregorio A, Andergassen U, Friedl T, Fasching P, Fehm T, Schneeweiss A, Beckmann M, Pantel K, Janni W, Rack B, Scholz C
BREAST CANCER RES TR. 2018;171(3):571-580.

Blockade of myeloid-derived suppressor cell expansion with all-trans retinoic acid increases the efficacy of anti-angiogenic therapy
Bauer R, Udonta F, Wroblewski M, Ben-Batalla I, Santos I, Taverna F, Kuhlencord M, Gensch V, Päsler S, Vinckier S, Brandner J, Pantel K, Bokemeyer C, Vogl T, Roth J, Carmeliet P, Loges S
CANCER RES. 2018;78(12):3220-3232.

Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib
Berger L, Janning M, Velthaus J, Ben-Batalla I, Schatz S, Falk M, Iglauer P, Simon R, Cao R, Forcato C, Manaresi N, Bramlett K, Buson G, Hanssen A, Tiemann M, Sauter G, Bokemeyer C, Riethdorf S, Reck M, Pantel K, Wikman H, Loges S
J THORAC ONCOL. 2018;13(12):e243-e246.

Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-Analysis: A Meta-analysis
Bidard F, Michiels S, Riethdorf S, Mueller V, Esserman L, Lucci A, Naume B, Horiguchi J, Gisbert-Criado R, Sleijfer S, Toi M, Garcia-Saenz J, Hartkopf A, Generali D, Rothé F, Smerage J, Muinelo-Romay L, Stebbing J, Viens P, Magbanua M, Hall C, Engebraaten O, Takata D, Vidal-Martínez J, Onstenk W, Fujisawa N, Diaz-Rubio E, Taran F, Cappelletti M, Ignatiadis M, Proudhon C, Wolf D, Bauldry J, Borgen E, Nagaoka R, Carañana V, Kraan J, Maestro M, Brucker S, Weber K, Reyal F, Amara D, Karhade M, Mathiesen R, Tokiniwa H, Llombart-Cussac A, Meddis A, Blanche P, d'Hollander K, Pantel K
JNCI-J NATL CANCER I. 2018;110(6):560-567.

Diagnosis, monitoring and prevention of exposure-related non-communicable diseases in the living and working environment DiMoPEx-project is designed to determine the impacts of environmental exposure on human health
Budnik L, Adam B, Albin M, Banelli B, Baur X, Belpoggi F, Bolognesi C, Broberg K, Gustavsson P, Göen T, Fischer A, Jarosinska D, Manservisi F, O'Kennedy R, Øvrevik J, Paunovic E, Ritz B, Scheepers P, Schlünssen V, Schwarzenbach H, Schwarze P, Sheils O, Sigsgaard T, Van Damme K, Casteleyn L
J OCCUP MED TOXICOL. 2018;13:6.

RAISEing VEGF-D's importance as predictive biomarker for ramucirumab in metastatic colorectal cancer patients
Carmeliet P, Li X, Treps L, Conradi L, Loges S
ANN ONCOL. 2018;29(3):527-529.

Circulating free DNA integrity and concentration as independent prognostic markers in metastatic breast cancer
Cheng J, Holland-Letz T, Wallwiener M, Surowy H, Cuk K, Schott S, Trumpp A, Pantel K, Sohn C, Schneeweiss A, Burwinkel B
BREAST CANCER RES TR. 2018;169(1):69-82.

Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization
Chen S, El-Heliebi A, Schmid J, Kashofer K, Czyż Z, Polzer B, Pantel K, Kroneis T, Sedlmayr P
JOVE-J VIS EXP. 2018;(135):e56394.

miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes
Croset M, Pantano F, Kan C, Bonnelye E, Descotes F, Alix-Panabières C, Lecellier C, Bachelier R, Allioli N, Hong S, Bartkowiak K, Pantel K, Clézardin P
CANCER RES. 2018;78(18):5259-5273.

Improved risk stratification by circulating tumor cell counts in pancreatic cancer
Effenberger K, Schroeder C, Hanssen A, Wolter S, Eulenburg C, Tachezy M, Gebauer F, Izbicki J, Pantel K, Bockhorn M
CLIN CANCER RES. 2018;24(12):2844-2850.

Techniques of using circulating tumor DNA as a liquid biopsy component in cancer management
Elazezy M, Joosse S
COMPUT STRUCT BIOTEC. 2018;16:370-378.

In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges T, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P
CLIN CHEM. 2018;64(3):536-546.

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells
Follain G, Osmani N, Azevedo A, Allio G, Mercier L, Karreman M, Solecki G, Garcia Leòn M, Lefebvre O, Fekonja N, Hille C, Chabannes V, Dollé G, Metivet T, Hovsepian F, Prudhomme C, Pichot A, Paul N, Carapito R, Bahram S, Ruthensteiner B, Kemmling A, Siemonsen S, Schneider T, Fiehler J, Glatzel M, Winkler F, Schwab Y, Pantel K, Harlepp S, Goetz J
DEV CELL. 2018;45(1):33-52.e12.

Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases
Gerstenberger W, Wrage M, Kettunen E, Pantel K, Anttila S, Steurer S, Wikman H
ANAL CELL PATHOL. 2018;2018:8651790.

Clinical relevance of size selection of circulating DNA
Grunt M, Hildebrand T, Schwarzenbach H
TRANSL CANCER RES. 2018;7(Suppl 2):S171-S184.

Metastasiertes kastrationsresistentes Prostatakarzinom: Neues zu Cabazitaxel unter Berücksichtigung der aktuellen Datenlage
Gschwend J, Albers P, Bögemann M, Goebell P, Heidenreich A, Klier J, König F, Machtens S, Pantel K, Thomas C
UROLOGE. 2018;57(1):34-39.

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen A, Riebensahm C, Mohme M, Joosse S, Velthaus J, Berger L, Bernreuther C, Glatzel M, Loges S, Lamszus K, Westphal M, Riethdorf S, Pantel K, Wikman H
CANCERS. 2018;10(12):E527.

Circulating tumour cells in prostate cancer
Hille C, Pantel K
NAT REV UROL. 2018;15(5):265-266.

Trastuzumab versus observation for HER2 non amplified early breast cancer with Circulating Tumor Cells (EORTC 90091-10093, BIG 1-12, Treat CTC): A randomized phase 2 trial
Ignatiadis M, Litière S, Rothe F, Riethdorf S, Proudhon C, Fehm T, Aalders K, Forstbauer H, Fasching P, Brain E, Vuylsteke P, Guardiola E, Lorenz R, Pantel K, Tryfonidis K, Janni W, Piccart M, Sotiriou C, Rack B, Pierga J
ANN ONCOL. 2018;29(8):1777-1783.

Anti-Angiogenics: Their Value in Lung Cancer Therapy
Janning M, Loges S
ONCOL RES TREAT. 2018;41(4):172-180.

Management immunvermittelter Nebenwirkungen - CME Fortbildung
Janning M, Loges S
Hautnah Dermatologie. 2018;34(1):38-46.

Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients
Joosse S, Souche F, Babayan A, Gasch C, Kerkhoven R, Ramos J, Fabre J, Riethdorf S, König A, Wikman H, Alix-Panabières C, Pantel K
CLIN CHEM. 2018;64(10):1505-1512.

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer
Lange T, Oh-Hohenhorst S, Joosse S, Pantel K, Hahn O, Gosau T, Dyshlovoy S, Wellbrock J, Feldhaus S, Maar H, Gehrcke R, Kluth M, Simon R, Schlomm T, Huland H, Schumacher U
SCI REP-UK. 2018;8:17535.

Intraoperative detection of circulating tumor cells in pulmonary venous blood during metastasectomy for colorectal lung metastases
Le U, Bronsert P, Picardo F, Riethdorf S, Haager B, Rylski B, Czerny M, Beyersdorf F, Wiesemann S, Pantel K, Passlick B, Kaifi J, Schmid S
SCI REP-UK. 2018;8(1):8751.

Personalisierte Krebstherapie 2018 - Fiktion oder Wirklichkeit?
Loges S, Bokemeyer C
InFo Onkologie. 2018;21 (S1):3-5.

Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients
Markou A, Lazaridou M, Paraskevopoulos P, Chen S, Świerczewska M, Budna J, Kuske A, Gorges T, Joosse S, Kroneis T, Zabel M, Sedlmayr P, Alix-Panabières C, Pantel K, Lianidou E
CLIN CHEM. 2018;64(2):297-306.

Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients
Ni Q, Stevic I, Pan C, Müller V, Oliviera-Ferrer L, Pantel K, Schwarzenbach H
SCI REP-UK. 2018;8:12974.

Exosomal microRNAs as tumor markers in epithelial ovarian cancer
Pan C, Stevic I, Müller V, Ni Q, Ferrer L, Pantel K, Schwarzenbach H
MOL ONCOL. 2018;12(11):1935-1948.

Disseminated breast tumour cells: biological and clinical meaning: biological and clinical meaning
Pantel K, Hayes D
NAT REV CLIN ONCOL. 2018;15(3):129-131.

Profiling circulating tumour cells and other biomarkers of invasive cancers
Poudineh M, Sargent E, Pantel K, Kelley S
NAT BIOMED ENG. 2018;2(2):72-84.

Aktuelles zur Liquid Biopsy
Reimers N, Hille C, Pantel K
InFo Onkologie. 2018;21(Suppl. 1):24-29.

Detection of microRNAs in circulating tumor cells
Riethdorf S
TRANSL CANCER RES. 2018;7 (Suppl 2):S197-S208.

Clinical applications of the CellSearch platform in cancer patients
Riethdorf S, O'Flaherty L, Hille C, Pantel K
ADV DRUG DELIVER REV. 2018;125:102-121.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

Inverse Perfusion Requirements of Supra- and Infratentorial Brain Metastases Formation
Schneider T, Kemmling A, Schroeder J, Pantel K, Glatzel M, Schoen G, Mohme M, Fiehler J, Gellißen S
FRONT NEUROL. 2018;9:391.

Endocrine Treatment with 2 Years of Tamoxifen versus 2 Years of Exemestane in Postmenopausal Patients with High-Risk Early Breast Cancer and Persisting Circulating Tumor Cells - First Results of the SUCCESS C Endocrine Treatment Sub-Study
Schochter F, Rack B, Tzschaschel M, Polasik A, Andergassen U, Trapp E, Alunni-Fabbroni M, Schneeweiss A, Müller V, Pantel K, Gade J, Lorenz R, Rezai M, Tesch H, Soeling U, Fehm T, Mahner S, Schindlbeck C, Lichtenegger W, Beckmann M, Fasching P, Janni W, Friedl T
ONCOL RES TREAT. 2018;41(3):93-98.

An inside view on liquid biopsies
Schwarzenbach H
TRANSL CANCER RES. 2018;7(Suppl 2):S99-S100.

Methods for quantification and characterization of microRNAs in cell-free plasma/serum, normal exosomes and tumor-derived exosomes
Schwarzenbach H
TRANSL CANCER RES. 2018;7(Suppl 2):S253-S263.

Commentary on "Detection and oncological effect of circulating tumor cells in patients with variant urothelial carcinoma histology treated with radical cystectomy."
Soave A, Riethdorf S, Dahlem R, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
UROL ONCOL-SEMIN ORI. 2018;36(7):347-348.

Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes
Soler A, Cayrefourcq L, Mazard T, Babayan A, Lamy P, Assou S, Assenat E, Pantel K, Alix-Panabières C
SCI REP-UK. 2018;8(1):15931.

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial
Stevic I, Müller V, Weber K, Fasching P, Karn T, Marmé F, Schem C, Stickeler E, Denkert C, van Mackelenbergh M, Salat C, Schneeweiss A, Pantel K, Loibl S, Untch M, Schwarzenbach H
BMC MED. 2018;16(1):179.

Die medikamentöse onkologische Therapie im Wandel - Aufbau von Strukturen zur Patientenversorgung
Velthaus J, Bokemeyer C, Loges S
InFo Onkologie. 2018;21(S1):10-18.

Absence of HER2 Expression of Circulating Tumor Cells in Patients with Non-Metastatic Esophageal Cancer
Woestemeier A, Ghadban T, Riethdorf S, Harms-Effenberger K, Konczalla L, Uzunoglu F, Izbicki J, Pantel K, Bockhorn M, Reeh M
ANTICANCER RES. 2018;38(10):5665-5669.

Correlation of Isotope Count With Sentinel Node Positivity in Vulvar Cancer
Wölber L, Joosse S, Grimm D, Mathey S, Mahner S, Burandt E, Klutmann S, Schmalfeldt B, Prieske K
INT J GYNECOL CANCER. 2018;28(7):1403-1409.

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells
Wroblewski M, Scheller-Wendorff M, Udonta F, Bauer R, Schlichting J, Zhao L, Ben Batalla I, Gensch V, Päsler S, Wu L, Wanior M, Taipaleenmäki H, Bolamperti S, Najafova Z, Pantel K, Bokemeyer C, Qi J, Hesse E, Knapp S, Johnsen S, Loges S
HAEMATOLOGICA. 2018;103(6):939-948.

Epithelial-mesenchymal plasticity in circulating tumor cells
Alix-Panabières C, Mader S, Pantel K
J MOL MED. 2017;95(2):133-142.

Biological Labels: Here comes the spaser
Alix-Panabières C, Pantel K
NAT MATER. 2017;16(8):790-791.

Characterization of Single Circulating Tumor Cells
Alix-Panabières C, Pantel K
FEBS LETT. 2017;591(15):2241 - 2250.

Detection of Circulating Plasma Cells in Multiple Myeloma
Alix-Panabières C, Pantel K
CLIN CHEM. 2017;63(12):1797-1798.

Plasma microRNA signature is associated with risk stratification in prostate cancer patients
Al-Qatati A, Akrong C, Stevic I, Pantel K, Awe J, Saranchuk J, Drachenberg D, Mai S, Schwarzenbach H
INT J CANCER. 2017;141(6):1231-1239.

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan A, Alawi M, Gormley M, Müller V, Wikman H, McMullin R, Smirnov D, Li W, Geffken M, Pantel K, Joosse S
ONCOTARGET. 2017;8(34):56066-56080.

Clinical Relevance of Serum HER2 and Circulating Tumor Cell Detection in Metastatic Breast Cancer Patients
Banys-Paluchowski M, Witzel I, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Pantel K, Fehm T, Müller V
ANTICANCER RES. 2017;37(6):3117-3128.

Evaluation of serum epidermal growth factor receptor (EGFR) in correlation to circulating tumor cells in patients with metastatic breast cancer
Banys-Paluchowski M, Witzel I, Riethdorf S, Rack B, Janni W, Fasching P, Solomayer E, Aktas B, Kasimir-Bauer S, Pantel K, Fehm T, Müller V
SCI REP-UK. 2017;7(1):Art. 17307.

Liquid Biopsies, What We Do Not Know (Yet)
Bardelli A, Pantel K
CANCER CELL. 2017;31(2):172-179.

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia
Ben Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus J, Rankin S, Clark R, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf T, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason G, Holyoake T, Loges S
CLIN CANCER RES. 2017;23(9):2289-2300.

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism
Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M
CANCER RES. 2017;77(5):1188-1199.

Immunotherapy of WAP-TNP mice with early stage mammary gland tumors
Bruns M, Deppert W
ONCOTARGET. 2017;8(40):67790-67804.

Letzte Aktualisierung aus dem FIS: 24.04.2025 - 00:33 Uhr